Rei Takeda, Kazuya Takahashi, Andreas Kronbichler, Daiichiro Akiyama, Shunichiro Hanai, Yoshiaki Kobayashi, Ayako Matsuki, Takeshi Umibe, Chisaki Ito, Toyohiko Sugimoto, Takao Sugiyama, Shun Yoshida, Yasuhide Nishio, Ikuo Nukui, Ayumu Nakashima, Hanae Wakabayashi, Katsuhiko Asanuma, Shunsuke Furuta, Hiroshi Nakajima, Daiki Nakagomi
INTRODUCTION: Glomerulonephritis is frequent in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and crucial to disease outcomes. We conducted a detailed assessment of renal pathology in Japanese patients with AAV, and developed a new score that would predict renal outcome. METHODS: Two hundred twenty-one patients who were diagnosed with AAV and underwent a kidney biopsy were enrolled. Data on glomerular, tubular, interstitial, and vascular lesions from kidney biopsies were analyzed; the 3 established classification and prognostic scoring systems (Berden Classification, Mayo Clinic/RPS Chronicity Score [MCCS], and ANCA Renal Risk Score [ARRS]) were validated...
March 2024: KI Reports