keyword
https://read.qxmd.com/read/38707619/depression-among-refugee-youth-in-an-outpatient-healthcare-center-prevalence-and-associated-factors
#1
JOURNAL ARTICLE
Lea Schumacher, Jette Echterhoff, Areej Zindler, Dana Barthel
BACKGROUND: Due to armed conflict and other crises, many children worldwide have to flee their home country and are, consequently, at a high risk for mental health problems. OBJECTIVE: As the majority of previous research on refugee minors focused on post-traumatic stress disorder (PTSD), we aimed to assess the prevalence and risk factors for depression in a clinical sample of refugee youth. METHODS: Data were collected during the standard diagnostic process in an outpatient refugee clinic in Germany...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38705779/predicting-dsm-5-ptsd-symptomatology-6-months-to-2-years-after-burn-the-role-of-early-psychological-risk-factors
#2
JOURNAL ARTICLE
Yi-Jen Su
BACKGROUND: Major burn injuries may have long-term mental health consequences, such as posttraumatic stress disorder (PTSD). This study extended prior work to investigate DSM-5 PTSD symptoms at 6 months, 1 year, and 2 years post-burn as well as the contribution of two sets of early psychological risk factors to DSM-5 PTSD symptoms: Established PTSD risk factors (prior adjustment problems, past trauma, perception of life threat, peritraumatic emotions and dissociation) and theory-derived cognitive factors (negative appraisals of the trauma and its sequelae, memory disorganization, trauma-related rumination, and thought suppression)...
April 26, 2024: Burns
https://read.qxmd.com/read/38701878/association-of-anhedonia-with-brain-derived-neurotrophic-factor-and-interleukin-10-in-major-depressive-disorder
#3
JOURNAL ARTICLE
Lirong Fu, Juanjuan Ren, Xiaoxia Lei, Yewei Wang, Xiaochang Chen, Rong Zhang, Qingyi Li, Xinyue Teng, Chaoyue Guo, Zenan Wu, Lingfang Yu, Dandan Wang, Yan Chen, Jinmei Qin, Aihua Yuan, Chen Zhang
BACKGROUND: Anhedonia, a core symptom of major depressive disorder (MDD), manifests in two forms: anticipatory and consummatory, reflecting a diminished capacity to anticipate or enjoy pleasurable activities. Prior studies suggest that brain-derived neurotrophic factor (BDNF) and interleukin-10 (IL-10) may play key roles in the emergence of anhedonia in MDD. The specific relationships between these biomarkers and the two forms of anhedonia remain unclear. This study investigated the potential links between BDNF, IL-10, and both forms of anhedonia in MDD patients...
May 1, 2024: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://read.qxmd.com/read/38699891/association-of-clinical-variables-and-thyroid-stimulating-hormone-with-psychotic-symptoms-in-patients-with-first-episode-and-drug-na%C3%A3-ve-major-depressive-disorder-with-elevated-fasting-blood-glucose-preliminary-exploratory-study-with-a-large-sample
#4
JOURNAL ARTICLE
Qian Yang, Qianjin Wang, Pu Peng, Tieqiao Liu, Xiangyang Zhang
BACKGROUND: Psychotic symptoms and elevated fasting blood glucose (FBG) are frequently observed in people with major depressive disorder (MDD), but there is a lack of research into this relationship within this cohort. AIMS: This study aimed to preliminarily explore the prevalence of psychotic symptoms and their predictors among patients with MDD and elevated FBG. METHOD: This study enrolled 1718 patients with first-episode and drug-naïve (FEDN) MDD...
May 3, 2024: BJPsych Open
https://read.qxmd.com/read/38694997/predictors-of-functional-impairment-in-bipolar-disorder-results-from-13-cohorts-from-seven-countries-by-the-global-bipolar-cohort-collaborative
#5
JOURNAL ARTICLE
Katherine E Burdick, Caitlin E Millett, Anastasia K Yocum, Cara M Altimus, Ole A Andreassen, Valerie Aubin, Raoul Belzeaux, Michael Berk, Joanna M Biernacka, Hilary P Blumberg, Anthony J Cleare, Claudia Diaz-Byrd, Caroline Dubertret, Bruno Etain, Lisa T Eyler, Brent P Forester, Janice M Fullerton, Mark A Frye, Sébastien Gard, Ophelia Godin, Emmanuel Haffen, Federica Klaus, Trine Vik Lagerberg, Marion Leboyer, Anabel Martinez-Aran, Susan McElroy, Philip B Mitchell, Emilie Olie, Phebe Olorunfemi, Christine Passerieux, Amy T Peters, Daniel L Pham, Mircea Polosan, Julia R Potter, Martha Sajatovic, Ludovic Samalin, Raymund Schwan, Megan Shanahan, Brisa Solé, Rebecca Strawbridge, Amanda L Stuart, Ivan Torres, Torrill Ueland, Eduard Vieta, Lana J Williams, Anna L Wrobel, Lakshmi N Yatham, Allan H Young, Andrew A Nierenberg, Melvin G McInnis
OBJECTIVES: Persistent functional impairment is common in bipolar disorder (BD) and is influenced by a number of demographic, clinical, and cognitive features. The goal of this project was to estimate and compare the influence of key factors on community function in multiple cohorts of well-characterized samples of individuals with BD. METHODS: Thirteen cohorts from 7 countries included n = 5882 individuals with BD across multiple sites. The statistical approach consisted of a systematic uniform application of analyses across sites...
October 2023: Focus: Journal of Life Long Learning in Psychiatry
https://read.qxmd.com/read/38687740/dietary-diversity-and-other-predictors-of-low-birth-weight-in-gurage-zone-ethiopia-prospective-study
#6
JOURNAL ARTICLE
Teshome Gensa Geta, Samson Gebremedhin, Saad Ahmed Abdiwali, Akinyinka O Omigbodun
BACKGROUND: Low birth weight (LBW) is a major public health problem in Ethiopia. Dietary diversity is a key indicator of maternal dietary adequacy that may affect birth weight but little is known about their relationship. Hence, this study aimed to assess the association of suboptimal maternal dietary diversity during pregnancy and low birth weight in Gurage Zone, Ethiopia. METHODS: The prospective study was conducted among 1062 pregnant women enrolled consecutively in between 16 to 20 gestational weeks and followed until delivery...
2024: PloS One
https://read.qxmd.com/read/38670606/screening-for-those-at-risk-for-anxiety-and-depression-warranting-further-clinical-evaluation-among-patients-presenting-to-breast-services-a-single-centre-cross-sectional-study
#7
JOURNAL ARTICLE
Sakina Husain, Shilpa Rao, Sridhar Suresh, Kevin Victor Albert Jesudoss, Balamurali Krishna, Jeffrey Pradeep Raj
OBJECTIVES: Studies show that anxiety and depression are widespread across patients presenting to outpatient services for medical illnesses. We expect similar or even higher prevalence in patients with breast complaints owing to the relevance of breasts in terms of sexuality, identity and confidence. Thus, this study was proposed to estimate the prevalence and identify risk factors for being at risk for anxiety and depression in patients seeking breast services. DESIGN: Descriptive, cross-sectional study...
April 25, 2024: BMJ Open
https://read.qxmd.com/read/38666648/effects-of-chronic-pain-diagnoses-on-the-antidepressant-efficacy-of-transcranial-magnetic-stimulation
#8
JOURNAL ARTICLE
Houtan Totonchi Afshar, Joel N Fishbein, Erica J Martinez, Gage M Chu, Mohammad A Shenasa, Dhakshin Ramanathan, Matthew S Herbert
OBJECTIVE: Major depressive disorder (MDD) and chronic pain are highly comorbid and bidirectionally related. Repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex is effective in treating MDD, but additional research is needed to determine if chronic pain interferes with rTMS for MDD. METHODS: Participants were 124 veterans (Mage = 49.14, SD = 13.83) scheduled for 30 sessions of rTMS across six weeks. Depression severity was monitored weekly using the Patient Health Questionnaire-9...
April 26, 2024: Psychosomatic Medicine
https://read.qxmd.com/read/38665721/micrornas-as-diagnostic-biomarkers-and-predictors-of-antidepressant-response-in-major-depressive-disorder-a-systematic-review
#9
REVIEW
Beatriz A Carneiro, Lívia N Franco Guerreiro-Costa, Daniel Lins-Silva, Daniela Faria Guimaraes, Lucca S Souza, Gustavo C Leal, Ana Teresa Caliman-Fontes, Graziele Beanes, Ryan Dos S Costa, Lucas C Quarantini
Despite the hardships of major depressive disorder (MDD), biomarkers for the diagnosis and pharmacological management of this condition are lacking. MicroRNAs are epigenetic mechanisms that could provide promising MDD biomarkers. Our aim was to summarize the findings and provide validation for the selection and use of specific microRNAs as biomarkers in the diagnosis and treatment of MDD. A systematic review was conducted using the PubMed/Medline, Cochrane, PsycINFO, Embase, and LILACS databases from March 2022 to November 2023, with clusters of terms based on "microRNA" and "antidepressant"...
March 2024: Curēus
https://read.qxmd.com/read/38663556/improving-usual-care-outcomes-in-major-depression-in-youth-by-targeting-memory-specificity-a-randomized-controlled-trial-of-adjunct-computerized-memory-specificity-training-c-mest
#10
JOURNAL ARTICLE
David John Hallford, David W Austin, Keisuke Takano, Joesph J Yeow, Danielle Rusanov, Matthew Fuller-Tyszkiewicz, Filip Raes
OBJECTIVE: Extending on previous findings that computerized MeST (c-MeST) improves memory specificity and depressive symptoms in Major Depressive Disorder (MDD) in adults, this study aimed to assess the effects of c-MeST in youth with MDD on memory specificity and depression in addition to other treatment. METHODS: Participants aged 15-25 (N = 359, 76 % female; M age = 19.2, SD = 3.1), receiving predominantly psychological therapy or counseling (85 %) and/or antidepressants (52 %) were randomized to usual care and c-MeST or usual care...
April 23, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38663555/daily-stress-reactivity-and-risk-appraisal-mediates-childhood-parental-abuse-predicting-adulthood-psychopathology-severity-an-18-year-longitudinal-mediation-analysis
#11
JOURNAL ARTICLE
Nur Hani Zainal, Chui Pin Soh, Natalia Van Doren
Identifying mechanisms of childhood abuse-adulthood psychopathology relations could facilitate preventive efforts, but most prior studies used cross-sectional or two-wave designs and did not test the effects of childhood maternal and paternal abuse separately. Our 18-year three-wave study thus determined if Wave 2 daily stress reactivity and risk appraisal severity mediated Wave 1 retrospectively-reported childhood maternal and paternal abuse on Wave 3 generalized anxiety disorder (GAD), major depressive disorder (MDD), panic disorder (PD), alcohol (AUD), and substance use disorder (SUD) self-rated symptom severity...
April 23, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38658936/relationship-between-cognitive-function-and-functional-outcomes-in-remitted-major-depression
#12
JOURNAL ARTICLE
Ruiqing Luo, Ningdan Fan, Yikai Dou, Yu Wang, Min Wang, Xiao Yang, Xiaohong Ma
BACKGROUND: Few studies have focused on functional impairment in depressed patients during symptomatic remission. The exact relationship between cognitive performance and functional outcomes of patients with Major depressive disorder (MDD) remains unclear. METHODS: Participants diagnosed with MDD were included and interviewed at both baseline and follow-up. Cognitive function was assessed during acute episodes using the Cambridge Neuropsychological Test Automated Battery (CANTAB), which targeted attention (Rapid Visual Processing - RVP), visual memory (Pattern Recognition Memory - PRM), and executive function (Intra-Extra Dimensional Set Shift - IED)...
April 24, 2024: BMC Psychiatry
https://read.qxmd.com/read/38657767/effects-of-anhedonia-on-health-related-quality-of-life-and-functional-outcomes-in-major-depressive-disorder-a-systematic-review-and-meta-analysis
#13
REVIEW
Sabrina Wong, Gia Han Le, Lee Phan, Taeho Greg Rhee, Roger Ho, Shakila Meshkat, Kayla M Teopiz, Angela T H Kwan, Rodrigo B Mansur, Joshua D Rosenblat, Roger S McIntyre
BACKGROUND: Major depressive disorder (MDD) is a heterogeneous group of mood disorders. A prominent symptom domain is anhedonia narrowly defined as a loss of interest and ability to experience pleasure. Anhedonia is associated with depressive symptom severity, MDD prognosis, and suicidality. We perform a systematic review and meta-analysis of extant literature investigating the effects of anhedonia on health-related quality of life (HRQoL) and functional outcomes in persons with MDD. METHODS: A literature search was conducted on PubMed, OVID databases, and SCOPUS for published articles from inception to November 2023, reporting on anhedonia and patient-reported outcomes in persons with MDD...
April 22, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38656607/lifetime-prevalence-comorbidities-and-sociodemographic-predictors-of-post-traumatic-stress-disorder-ptsd-the-national-epidemiology-of-iranian-children-and-adolescents-psychiatric-disorders-ircap
#14
JOURNAL ARTICLE
Zahra Hooshyari, Mohammad Reza Mohammadi, Maryam Salmanian, Nastaran Ahmadi, Ali Khaleghi, Amir Garakani
OBJECTIVE: The aims of this study were to (a) evaluate the lifetime prevalence of post-traumatic stress disorder (PTSD) according to sociodemographic characteristics, (b) determine sociodemographic factors associated with PTSD, (c) estimate the lifetime prevalence rates of comorbidities by age and gender, and (d) assess the proportion of traumatic events in the non-PTSD sample and the PTSD sample, according to gender. METHODS: The data used for the present study were obtained from the IRCAP study which was a cross-sectional, community-based study on 29,250 children and adolescents aged 6-18 years from all provinces of Iran, which was done using multistage cluster sampling...
April 24, 2024: European Child & Adolescent Psychiatry
https://read.qxmd.com/read/38655856/operational-definitions-of-poly-victimization-a-scoping-review
#15
REVIEW
Christin M Ogle, Caroline Harmon-Darrow, Lisa Fedina, Darlene Nichols, Carrie F Mulford, Bethany L Backes
Throughout the last two decades, research on poly-victimization (PV) has evolved from examinations of a core set of past-year victimization types in youth samples to investigations of a broad range of victimization types experienced during variable time intervals in diverse samples of varying ages. As the concept of PV expands, greater clarity regarding the definition and measurement of PV is needed to advance understanding of its risk and protective factors as well as its associated outcomes. This scoping review aimed to (a) identify approaches used to operationally define and measure PV across studies and (b) synthesize empirical findings concerning risk factors and outcomes associated with PV...
April 24, 2024: Trauma, Violence & Abuse
https://read.qxmd.com/read/38650309/leveraging-dna-methylation-to-predict-treatment-response-in-major-depressive-disorder-a-critical-review
#16
REVIEW
Jan Dahrendorff, Glenn Currier, Monica Uddin
Major depressive disorder (MDD) is a debilitating and prevalent mental disorder with a high disease burden. Despite a wide array of different treatment options, many patients do not respond to initial treatment attempts. Selection of the most appropriate treatment remains a significant clinical challenge in psychiatry, highlighting the need for the development of biomarkers with predictive utility. Recently, the epigenetic modification DNA methylation (DNAm) has emerged to be of great interest as a potential predictor of MDD treatment outcomes...
April 22, 2024: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://read.qxmd.com/read/38638745/factors-affecting-upper-limb-fracture-opioid-requirements
#17
JOURNAL ARTICLE
James Zhang, Florence Bradshaw, Michal Duchniewicz, Fernanda W Fernandes, Rahul Geetala, Matjia Krkovic
Introduction Understanding the different opioid pain relief requirements between patients with upper limb fractures can be useful in forming specific evidence-based guidelines and balancing patient-clinician prescribing discussions with opioid stewardship. We investigated the predictors for opioid requirements in upper limb fractures. Methods We retrospectively investigated all upper limb fractures from the shoulder to the wrist treated at a major trauma center from January 2015 to January 2022. The data collected consisted of fracture location, demographics, comorbidities, and management options...
March 2024: Curēus
https://read.qxmd.com/read/38636108/evaluating-the-prevalence-and-risk-factors-for-depression-in-patients-with-temporal-lobe-epilepsy-with-hippocampal-sclerosis-a-cross-sectional-multicenter-study
#18
JOURNAL ARTICLE
Bandar N Aljafen, Ruwa Alneseyan, Taim Muayqil, Mashael O Alkhateeb, Mubarak M Aldosari, Aya Alsermani, Lujain Alnakhli, Renad Althomali, Razan Alnami, Ruba Alqahtani, Lama Ibrahim, Fawzi Babtain
BACKGROUND: Epilepsy frequently accompanies Major Depressive Disorder (MDD). Notably, people with temporal lobe epilepsy and hippocampal sclerosis may face an increased susceptibility to MDD, as evidence indicates the involvement of the limbic system in the development of emotional symptoms. OBJECTIVES: To determine the prevalence and predictors of depression in temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) and compare them to those of other epilepsy types...
April 17, 2024: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38634682/prevalence-and-predictors-of-minimum-acceptable-diet-mad-feeding-among-tribal-children-aged-6-23-months-in-india
#19
JOURNAL ARTICLE
Manas Ranjan Pradhan, Daisy Saikia, Sourav Mondal, Prasanna Kumar Mudi
Minimum acceptable diet (MAD) that combines minimum dietary diversity (MDD) and minimum meal frequency (MMF) is one of the eight core indicators for assessing infant and young child feeding (IYCF) practices for children aged 6-23 months. With low MAD, young children and infants are more susceptible to undernutrition. The study assesses the prevalence and predictors of MAD among tribal children aged 6-23 months in India. Descriptive, bivariate, and multivariate analyzes were performed on data from 6326 tribal children of the National Family Health Survey (2019-21)...
April 18, 2024: Biodemography and Social Biology
https://read.qxmd.com/read/38630744/teenage-blues-predictors-of-depression-among-adolescents-in-nigeria
#20
JOURNAL ARTICLE
Adefunke DadeMatthews, Chukwuemeka Nzeakah, Lucky Onofa, Oluwagbemiga DadeMatthews, Temitope Ogundare
BACKGROUND: Depressive disorders, with a prevalence of 15-21%, are among the most common disorders in children and adolescents, and increases the risk of suicide, the second leading cause of death in children aged 10 to 19. AIM: To determine the prevalence and correlates of depressive disorders among senior students attending secondary schools in Abeokuta. METHOD: The study was conducted in five schools randomly selected from a representative sample and was carried out in 2 phases...
2024: PloS One
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