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Celiac disease hypothyroid

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https://www.readbyqxmd.com/read/29373441/the-impact-of-thyroid-autoimmunity-on-thyroid-function-in-12-year-old-children-with-celiac-disease
#1
Fredrik Norström, Maria van der Pals, Anna Myléus, Solveig Hammarroth, Lotta Högberg, Anders Isaksson, Anneli Ivarsson, Annelie Carlsson
OBJECTIVES: Celiac disease (CD) is associated with thyroid autoimmunity and other autoimmune diseases. However, data are lacking regarding the relationship between thyroid autoimmunity and thyroid function, especially in regard to CD. Our aim was to investigate the impact of thyroid autoimmunity on thyroid function in 12-year-old children with CD compared to their healthy peers. METHODS: A case-referent study was conducted as part of a CD screening of 12-year-olds...
January 25, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29315154/characteristics-and-comorbidities-of-inpatients-without-celiac-disease-on-a-gluten-free-diet
#2
John W Blackett, Meghana Shamsunder, Norelle R Reilly, Peter H R Green, Benjamin Lebwohl
OBJECTIVES: Despite the increasing popularity of gluten-free diet (GFD), the demographic characteristics and medical features of patients without celiac disease on this diet have not been extensively investigated.We aimed to characterize the medical conditions and demographic backgrounds of hospitalized patients without celiac disease who adhere to a GFD, to further understand their reasons for gluten avoidance. MATERIALS AND METHODS: We performed an observational cohort study on all inpatients at Columbia University Medical Center on a GFD in 2011-2016, excluding those with celiac disease, compared with age-matched and sex-matched inpatients on a regular diet...
January 8, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29127609/gender-based-differences-in-a-population-based-cohort-with-celiac-disease-more-alike-than-unalike
#3
Claire L Jansson-Knodell, Katherine S King, Joseph J Larson, Carol T Van Dyke, Joseph A Murray, Alberto Rubio-Tapia
BACKGROUND: There is a gap in research focused on gender-based differences in non-referral populations with celiac disease. AIMS: The aim of this study was to estimate those differences in a unique population-based cohort of patients with celiac disease with respect to (1) presenting symptoms, (2) associated autoimmune disorders, and (3) survival. METHODS: Clinical data were systematically abstracted from the electronic medical record of a population-based incident cohort of patients with celiac disease...
November 10, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28695483/diagnosis-and-management-of-treatment-refractory-hypothyroidism-an-expert-consensus-report
#4
REVIEW
M Centanni, S Benvenga, I Sachmechi
There is a frequently encountered subset of hypothyroid patients who are refractory to standard thyroid hormone replacement treatment and require unexpectedly high doses of levothyroxine. In addition to clinical situations where hypothyroid patients are non-compliant, or where there is the possibility of excipient-induced disease exacerbation (gluten/celiac disease), therapeutic failure may be due to impaired absorption of the administered drug. The common approach to managing patients with unusual thyroxine needs is to escalate the dose of levothyroxine until targeted TSH levels are achieved...
December 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28634534/etiological-factors-of-short-stature-in-children-and-adolescents-experience-at-a-tertiary-care-hospital-in-egypt
#5
Almontaser Hussein, Hekma Farghaly, Eman Askar, Kotb Metwalley, Khaled Saad, Asmaa Zahran, Hisham A Othman
BACKGROUND: Accurate anthropometric measurements and critical analysis of growth data allow the clinician to promptly recognize children with short stature. The aim of this study was to determine the frequency of etiological factors causing short stature among children referred to the pediatric endocrinology clinic of Assiut University Children's Hospital, the main tertiary care center in Upper Egypt. METHODS: We conducted this descriptive observational study from May 2012 to December 2015, to analyze 637 children (boys 354, girls 283) with short stature...
May 2017: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28574011/coexistence-of-celiac-disease-type-1-diabetes-mellitus-in-children
#6
Preeti Singh, Anju Seth, Praveen Kumar, Sushma Sajjan
BACKGROUND & OBJECTIVES: Type 1 diabetes mellitus (T1DM) and celiac disease (CD) tend to co-exist due to similar underlying genetic predisposition. Failure to recognize CD in patients with T1DM predisposes them to complications. The present study was aimed to assess children with T1DM for the presence of CD. METHODS: This was a retrospective analysis of the records of children with T1DM attending paediatric endocrinology clinic at a tertiary care hospital in north India from January 2006 to May 2014...
January 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28457528/disease-associations-with-isolated-elevations-of-each-of-the-four-igg-subclasses
#7
Sarah Engelhart, Robert J Glynn, Peter H Schur
PURPOSE: Immunoglobulin G4-related disease (IgG4-RD) is a relatively newly defined disease entity that refers to a group of immune-mediated disorders that have certain histopathologic, serologic, and clinical features in common. IgG4-RD is often associated with elevated serum IgG4. The discovery of IgG4-RD highlights the scarcity of literature examining elevations in other IgG subclasses and their potential associations to disease. In this retrospective chart review study, we aim to address that gap, by exploring disease associations in patients with isolated IgG subclass elevations...
October 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28400547/anemia-in-thyroid-diseases
#8
Ewelina Szczepanek-Parulska, Aleksandra Hernik, Marek Ruchała
Anemia is a frequent, although often underestimated, clinical condition accompanying thyroid diseases. Despite the fact that anemia and thyroid dysfunction often occur simultaneously, the causative relationship between the disorders remains ambiguous. Thyroid hormones stimulate the proliferation of erythrocyte precursors both directly and via erythropoietin production enhancement, while iron-deficient anemia negatively influences thyroid hormone status. Thus, different forms of anemia might develop in the course of thyroid dysfunction...
May 31, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28315909/a-concise-review-of-hashimoto-thyroiditis-ht-and-the-importance-of-iodine-selenium-vitamin-d-and-gluten-on-the-autoimmunity-and-dietary-management-of-ht-patients-points-that-need-more-investigation
#9
REVIEW
Michael I Liontiris, Elias E Mazokopakis
Hashimoto's thyroiditis (HT) is a chronic autoimmune thyroid disease caused by an interaction between genetic factors and environmental conditions, both of which are yet to be fully understood. The management of HT depends on its clinical manifestations, commonly including diffuse or nodular goiter with euthyroidism, subclinical hypothyroidism and permanent hypothyroidism. However, in most cases of patients with HT, lifelong levothyroxine substitution is required. The additional role of diet for the management of HT is usually overlooked...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28298278/pediatric-celiac-disease-follow-up-in-the-spotlight
#10
REVIEW
Francesco Valitutti, Chiara Maria Trovato, Monica Montuori, Salvatore Cucchiara
The follow-up of celiac disease (CD) is challenging due to the scarcity of published data and the lack of standardized evidence-based protocols. The worldwide frequency and methods of CD follow-up appear to be heavily influenced by expert opinions of the individual physicians who assess children with CD. The aim of this review was to summarize the available studies on CD follow-up in children. We conducted a literature search with the use of PubMed, Medline, and Embase (from 1900 to 15 December 2016) for terms relevant to this review, including CD, follow-up, dietary adherence or dietary compliance, nutrition, comorbidities, complications, and quality of life...
March 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28276835/autoimmune-gastritis-relationships-with-anemia-and-helicobacter-pylori-status
#11
Vincenzo Villanacci, Giovanni Casella, Francesco Lanzarotto, Camillo Di Bella, Angelo Sidoni, Moris Cadei, Tiziana Salviato, Maria Pina Dore, Gabrio Bassotti
BACKGROUND: Autoimmune gastritis (AIG) is a gastric pathologic condition affecting the mucosa of the fundus and the body and eventually leading to hypo-achlorhydria. AIMS: We report our clinical and pathological experience with AIG. METHODS: Data from patients with a diagnosis of AIG seen in the period January 2002-December 2012 were retrieved. Only patients with complete sets of biopsies were analyzed. RESULTS: Data from 138 patients were available for analysis...
June 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27916669/prevalence-and-morbidity-of-undiagnosed-celiac-disease-from-a%C3%A2-community-based-study
#12
Rok Seon Choung, Scott A Larson, Shahryar Khaleghi, Alberto Rubio-Tapia, Inna G Ovsyannikova, Katherine S King, Joseph J Larson, Brian D Lahr, Gregory A Poland, Michael J Camilleri, Joseph A Murray
BACKGROUND & AIMS: Little is known about the prevalence and burden of undiagnosed celiac disease in individuals younger than age 50. We determined the prevalence and morbidity of undiagnosed celiac disease in individuals younger than age 50 in a community. METHODS: We tested sera from 31,255 residents of Olmsted County, Minnesota (<50 y), without a prior diagnosis of celiac disease assay using an assay for IgA against tissue transglutaminase; in subjects with positive test results, celiac disease was confirmed using an assay for endomysial IgA...
March 2017: Gastroenterology
https://www.readbyqxmd.com/read/27845544/clinical-spectrum-of-celiac-disease-in-children-in-sistan-and-baluchestan-province
#13
Touran Shahraki, Ivor D Hill
BACKGROUND: The clinical manifestations of celiac disease (CD) have changed in the past decades. There are currently little data describing the initial clinical manifestations of CD in children in Iran. This study describes the initial presentation of children with suspected CD from a geographically defined region in Iran. METHOD: Medical records of children seen in 2007 - 2015 from Sistan and Baluchestan province, Iran, with suspected CD were reviewed. After obtaining TTG-IgA and IgA, subjects were divided into three groups according to presenting symptoms: GI, non-GI, and asymptomatic group...
November 2016: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/27784959/endocrine-manifestations-in-celiac-disease
#14
REVIEW
Hugh James Freeman
Celiac disease (CD) is an autoimmune small intestinal mucosal disorder that often presents with diarrhea, malabsorption and weight loss. Often, one or more associated endocrine disorders may be associated with CD. For this review, methods involved an extensive review of published English-language materials. In children and adolescents, prospective studies have demonstrated a significant relationship to insulin-dependent or type 1 diabetes, whereas in adults, autoimmune forms of thyroid disease, particularly hypothyroidism, may commonly co-exist...
October 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27489467/celiac-disease-in-children-and-adolescents-with-hashimoto-thyroiditis
#15
Hale Tuhan, Sakine Işık, Ayhan Abacı, Erdem Şimşek, Ahmet Anık, Özden Anal, Ece Böber
AIM: The aim of this study was to evaluate clinical and laboratory findings and determine the prevalence of celiac disease (CD) in children with Hashimoto thyroiditis (HT). MATERIAL AND METHODS: The data of a total of 80 patients with positive anti-thyroid antibodies who were aged between 6 and 17.9 years were retrospectively studied. Age, gender, complaints at the time of presentation, family history of thyroid disorders, clinical and laboratory findings were recorded...
June 2016: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/27429649/overweight-among-children-and-adolescent-with-type-i-diabetes-mellitus-prevalence-and-associated-factors
#16
Verônica Medeiros da Costa, Patricia de Carvalho Padilha, Géssica Castor Fontes de Lima, Aline Alves Ferreira, Jorge Luiz Luescher, Luciana Porto, Wilza Arantes Ferreira Peres
OBJECTIVES: Describe the overweight frequency (overweight and obesity) and identify the factors associated with this in children and adolescents with type 1 diabetes mellitus (T1DM) treated at a University Children's Hospital in Rio de Janeiro. METHODS: This is an analytical cross-sectional study, which included patients diagnosed with T1DM who had complete anthropometric data (weight and height) and excluded those using drugs with effect on weight gain, genetic syndromes, celiac disease, hypothyroidism, renal failure and other chronic diseases, and pregnant women...
2016: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/27423071/evaluation-of-therapeutics-management-patterns-and-glycemic-control-of-pediatric-type-1-diabetes-mellitus-patients-in-turkey-a-nationwide-cross-sectional-study
#17
Şükrü Hatun, Hüseyin Demirbilek, Şükran Darcan, Ayşegül Yüksel, Cigdem Binay, Damla Gökşen Şimşek, Cengiz Kara, Ergun Çetinkaya, Tolga Ünüvar, Ahmet Uçaktürk, Filiz Tütüncüler, Yaşar Cesur, Ruveyde Bundak, Halil Sağlam, Enver Şimşek, Abdullah Bereket
AIMS: To evaluate the management strategies, glycemic control and complications of pediatric type 1 diabetes mellitus (T1DM) patients in Turkey. METHODS: Study included 498 patients with T1DM between the ages 1-18. Data provided from patients' hospital files were recorded on standard case report forms by applicant clinicians within the 3months of data collection period between October 2012 and July 2013. RESULTS: Mean age of patients was 11...
September 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/27366039/is-pancreatic-exocrine-insufficiency-in-celiac-disease-related-to-structural-alterations-in-pancreatic-parenchyma
#18
Surinder S Rana, Arvind Dambalkar, Puneet Chhabra, Ravi Sharma, Ritambhra Nada, Vishal Sharma, Satyavati Rana, Deepak K Bhasin
BACKGROUND: Although exocrine pancreatic insufficiency (EPI) has been reported in a number of patients with celiac disease (CD), it is not clear if this is primarily a functional or a structural defect. We studied pancreatic structural abnormalities by endoscopic ultrasound (EUS) in adult CD patients with EPI. METHODS: Pancreatic exocrine function was prospectively assessed in 36 recently diagnosed CD patients (mean age: 29.8 years) by measuring fecal elastase. Pancreatic structural changes were assessed in CD patients with EPI by EUS and elastography...
July 2016: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/27348318/the-severity-of-symptoms-related-to-irritable-bowel-syndrome-is-a-risk-factor-for-the-misclassification-of-significant-organic-disease
#19
Dan Carter, Marc Beer-Gabel, Estela Derazne, Dorit Tzur, Eytan Bardan
BACKGROUND AND AIMS: The diagnosis of irritable bowel syndrome (IBS) is based mainly on clinical evaluation. The reported incidence of misclassification of significant organic diseases in previously diagnosed IBS patients differs between studies. The aim of this study was to examine the incidence and risk factors for the misclassification of significant organic disease [colon cancer, inflammatory bowel disease (IBD), Celiac disease, and thyroid dysfunction] in a cohort of young patients with symptoms attributed to IBS...
June 24, 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27256300/prevalence-of-celiac-disease-in-patients-with-autoimmune-thyroid-disease-a-meta-analysis
#20
Abhik Roy, Monika Laszkowska, Johan Sundström, Benjamin Lebwohl, Peter H R Green, Olle Kämpe, Jonas F Ludvigsson
BACKGROUND: Several screening studies have indicated an increased prevalence of celiac disease (CD) among individuals with autoimmune thyroid disease (ATD), but estimates have varied substantially. OBJECTIVE: The aim of this study was to examine the prevalence of CD in patients with ATD. METHOD: A systematic review was conducted of articles published in PubMed Medline or EMBASE until September 2015. Non-English papers with English-language abstracts were also included, as were research abstracts without full text available when relevant data were included in the abstract...
July 2016: Thyroid: Official Journal of the American Thyroid Association
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