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"Near infrared spectroscopy"

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https://www.readbyqxmd.com/read/28330736/hyperspectral-imaging-using-near-infrared-spectroscopy-to-monitor-coat-thickness-uniformity-in-the-manufacture-of-a-transdermal-drug-delivery-system
#1
Naresh Pavurala, Xiaoming Xu, Yellela S R Krishnaiah
Hyperspectral imaging using near infrared spectroscopy (NIRS) integrates spectroscopy and conventional imaging to obtain both spectral and spatial information of materials. The non-invasive and rapid nature of hyperspectral imaging using NIRS makes it a valuable process analytical technology (PAT) tool for in-process monitoring and control of the manufacturing process for transdermal drug delivery systems (TDS). The focus of this investigation was to develop and validate the use of Near Infra-red (NIR) hyperspectral imaging to monitor coat thickness uniformity, a critical quality attribute (CQA) for TDS...
March 19, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28329240/effect-of-breathing-oxygen-enriched-air-on-exercise-performance-in-patients-with-precapillary-pulmonary-hypertension-randomized-sham-controlled-cross-over-trial
#2
Silvia Ulrich, Elisabeth D Hasler, Stéphanie Saxer, Michael Furian, Séverine Müller-Mottet, Stephan Keusch, Konrad E Bloch
Aims: The purpose of the current trial was to test the hypothesis that breathing oxygen-enriched air increases exercise performance of patients with pulmonary arterial or chronic thrombo-embolic pulmonary hypertension (PAH/CTEPH) and to investigate involved mechanisms. Methods and results: Twenty-two patients with PAH/CTEPH, eight women, means ± SD 61 ± 14 years, resting mPAP 35 ± 9mmHg, PaO2 ambient air >7.3 kPa, underwent four bicycle ergospirometries to exhaustion on different days, while breathing oxygen-enriched (FiO2 0...
March 11, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28328980/early-biomarkers-of-brain-injury-and-cerebral-hypo-and-hyperoxia-in-the-safeboosc-ii-trial
#3
Anne M Plomgaard, Thomas Alderliesten, Topun Austin, Frank van Bel, Manon Benders, Olivier Claris, Eugene Dempsey, Monica Fumagalli, Christian Gluud, Cornelia Hagmann, Simon Hyttel-Sorensen, Petra Lemmers, Wim van Oeveren, Adelina Pellicer, Tue H Petersen, Gerhard Pichler, Per Winkel, Gorm Greisen
BACKGROUND: The randomized clinical trial, SafeBoosC II, examined the effect of monitoring of cerebral oxygenation by near-infrared spectroscopy combined with a guideline on treatment when cerebral oxygenation was out of the target range. Data on cerebral oxygenation was collected in both the intervention and the control group. The primary outcome was the reduction in the burden of cerebral hypo- and hyperoxia between the two groups. In this study we describe the associations between the burden of cerebral hypo- and hyperoxia, regardless of allocation to intervention or control group, and the biomarkers of brain injury from birth till term equivalent age that was collected as secondary and explorative outcomes in the SafeBoosC II trial...
2017: PloS One
https://www.readbyqxmd.com/read/28327077/regional-muscle-tissue-saturation-is-an-indicator-of-global-inadequate-circulation-during-cardiopulmonary-bypass-a-randomized-porcine-study-using-muscle-intestinal-and-brain-tissue-metabolomics
#4
Sisse Anette Thomassen, Benedict Kjærgaard, Preben Sørensen, Jan Jesper Andreasen, Anders Larsson, Bodil Steen Rasmussen
BACKGROUND: Muscle tissue saturation (StO2) measured with near-infrared spectroscopy has generally been considered a measurement of the tissue microcirculatory condition. However, we hypothesized that StO2 could be more regarded as a fast and reliable measure of global than of regional circulatory adequacy and tested this with muscle, intestinal and brain metabolomics at normal and two levels of low cardiopulmonary bypass blood flow rates in a porcine model. METHODS: Twelve 80 kg pigs were connected to normothermic cardiopulmonary bypass with a blood flow of 60 mL/kg/min for one hour, reduced randomly to 47...
April 2017: Perfusion
https://www.readbyqxmd.com/read/28326623/neurophysiological-assessment-of-acute-pain-in-infants-a-scoping-review-of-research-methods
#5
REVIEW
B Benoit, R Martin-Misener, A Newman, M Latimer, M Campbell-Yeo
A systematic scoping search to describe the neurophysiological methods used in infant acute pain assessment research was conducted. Of the 2411 abstracts screened, 19 articles were retained. Nine studies utilized near infrared spectroscopy (NIRS), two utilized functional magnetic resonance imaging (fMRI), and eight utilized electroencephalography (EEG). There was methodological variability in studies utilizing NIRS, whereas EEG and fMRI studies reported consistent methods. Of the eight EEG studies, six identified a nociceptive specific event-related potential...
March 22, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28324790/a-new-approach-to-estimating-the-evoked-hemodynamic-response-applied-to-dual-channel-functional-near-infrared-spectroscopy
#6
Reza Arefi Shirvan, Seyed Kamaledin Setarehdan, Ali Motie Nasrabadi
BACKGROUND: Brain activity can be measured non-invasively by means of functional near-infrared spectroscopy (fNIRS) which records hemodynamics of the brain tissue. Sensitivity of fNIRS to the brain activity is however being affected by natural physiological brain hemodynamics (systemic interferences). Functional hemodynamic signal extraction from physiological interferences still remains a challenging task. NEW METHOD: This paper presents a novel effective algorithm for real-time physiological interference reduction and recovery of the evoked brain activity using a dual channel fNIRS system...
March 18, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28324168/the-effect-of-eccentric-exercise-with-blood-flow-restriction-on-neuromuscular-activation-microvascular-oxygenation-and-the-repeated-bout-effect
#7
Jakob D Lauver, Trent E Cayot, Timothy Rotarius, Barry W Scheuermann
PURPOSE: To examine the effect of low-intensity eccentric contractions with and without blood flow restriction (BFR) on microvascular oxygenation, neuromuscular activation, and the repeated bout effect (RBE). METHODS: Participants were randomly assigned to either low-intensity (LI), low-intensity with BFR (LI-BFR), or a control (CON) group. Participants in LI and LI-BFR performed a preconditioning bout of low-intensity eccentric exercise prior to about of maximal eccentric exercise...
March 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28323801/predicting-acute-compartment-syndrome-pacs-the-role-of-continuous-monitoring
#8
Andrew H Schmidt, Michael J Bosse, Katherine P Frey, Robert V OʼToole, Daniel J Stinner, Daniel O Scharfstein, Vadim Zipunnikov, Ellen J MacKenzie
The diagnosis of acute compartment syndrome (ACS) is a common clinical challenge among patients who sustain high-energy orthopaedic trauma, largely because no validated criteria exist to reliably define the presence of the condition. In the absence of validated diagnostic standards, concern for the potential clinical and medicolegal impact of a missed compartment syndrome may result in the potential overuse of fasciotomy in "at-risk" patients. The goal of the Predicting Acute Compartment Syndrome Study was to develop a decision rule for predicting the likelihood of ACS that would reduce unnecessary fasciotomies while guarding against potentially missed ACS...
April 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28321639/brain-oxygenation-declines-in-elite-kenyan-runners-during-a-maximal-interval-training-session
#9
Jordan Santos-Concejero, F Billaut, L Grobler, J Oliván, T D Noakes, R Tucker
PURPOSE: The purpose of this study was to characterise the cerebral oxygenation (Cox) response during a high-intensity interval training session in Kenyan runners, and to examine any relationship with running performance. METHODS: 15 Kenyan runners completed a 5-km time trial (TT) and a Fatigue Training Test on a treadmill (repeated running bouts of 1-km at a pace 5% faster than their mean 5-km TT pace with a 30-s recovery until exhaustion). Changes in Cox were monitored via near-infrared spectroscopy through concentration changes in oxy- and deoxy-haemoglobin (Δ[O2Hb] and Δ[HHb]), tissue oxygenation index (TOI), and total hemoglobin index (nTHI)...
March 20, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28319185/real-time-monitoring-of-human-blood-brain-barrier-disruption
#10
Vesa Kiviniemi, Vesa Korhonen, Jukka Kortelainen, Seppo Rytky, Tuija Keinänen, Timo Tuovinen, Matti Isokangas, Eila Sonkajärvi, Topi Siniluoto, Juha Nikkinen, Seppo Alahuhta, Osmo Tervonen, Taina Turpeenniemi-Hujanen, Teemu Myllylä, Outi Kuittinen, Juha Voipio
Chemotherapy aided by opening of the blood-brain barrier with intra-arterial infusion of hyperosmolar mannitol improves the outcome in primary central nervous system lymphoma. Proper opening of the blood-brain barrier is crucial for the treatment, yet there are no means available for its real-time monitoring. The intact blood-brain barrier maintains a mV-level electrical potential difference between blood and brain tissue, giving rise to a measurable electrical signal at the scalp. Therefore, we used direct-current electroencephalography (DC-EEG) to characterize the spatiotemporal behavior of scalp-recorded slow electrical signals during blood-brain barrier opening...
2017: PloS One
https://www.readbyqxmd.com/read/28303659/invasive-characterization-of-atherosclerotic-plaque-in-patients-with-peripheral-arterial-disease-using-near-infrared-spectroscopy-intravascular-ultrasound
#11
Amr E Abbas, Sibin K Zacharias, James A Goldstein, Ivan D Hanson, Robert D Safian
OBJECTIVES: We describe the characteristics of atherosclerotic plaque in patients with peripheral arterial disease (PAD) using near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) BACKGROUND: Imaging and autopsy studies have described atherosclerotic plaque in different vascular beds, including varying degrees of lipid, fibrosis, and calcification. Recently, NIRS has been validated as an accurate method for detecting lipid-core plaque (LCP) in the coronary circulation. Invasive evaluation of plaque composition using NIRS-IVUS has not been reported in different peripheral arterial circulations...
March 17, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28303219/new-sensor-technologies-in-quality-evaluation-of-chinese-materia-medica-2010-2015
#12
REVIEW
Xiaosu Miao, Qingyu Cui, Honghui Wu, Yanjiang Qiao, Yanfei Zheng, Zhisheng Wu
New sensor technologies play an important role in quality evaluation of Chinese materia medica (CMM) and include near-infrared spectroscopy, chemical imaging, electronic nose and electronic tongue. This review on quality evaluation of CMM and the application of the new sensors in this assessment is based on studies from 2010 to 2015, with prospects and opportunities for future research.
March 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28302943/cerebral-hemodynamics-and-metabolism-during-cardiac-arrest-and-cardiopulmonary-resuscitation-using-hyperspectral-near-infrared-spectroscopy
#13
Reyhaneh Nosrati, Steve Lin, Andrew Ramadeen, Dena Monjazebi, Paul Dorian, Vladislav Toronov
BACKGROUND: Maintaining cerebral oxygen delivery and metabolism during cardiac arrest (CA) through resuscitation is essential to improve the survival rate while avoiding brain injury. The effect of CA and cardiopulmonary resuscitation (CPR) on cerebral and muscle oxygen delivery and metabolism is not clearly quantified.Methods and Results:A novel hyperspectral near-infrared spectroscopy (hNIRS) technique was developed and evaluated to measure cerebral oxygen delivery and aerobic metabolism during ventricular fibrillation (VF) CA and CPR in 14 pigs...
March 10, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28302079/near-infrared-spectroscopy-as-a-predictor-of-clinical-deterioration-a-case-report-of-two-infants-with-duct-dependent-congenital-heart-disease
#14
Mirthe J Mebius, Gideon J du Marchie Sarvaas, Diana W Wolthuis, Beatrijs Bartelds, Martin C J Kneyber, Arend F Bos, Elisabeth M W Kooi
BACKGROUND: Some infants with congenital heart disease are at risk of in-hospital cardiac arrest. To better foresee cardiac arrest in infants with congenital heart disease, it might be useful to continuously assess end-organ perfusion. Near-infrared spectroscopy is a non-invasive method to continuously assess multisite regional tissue oxygen saturation. CASE PRESENTATION: We report on two infants with duct-dependent congenital heart disease who demonstrated a gradual change in cerebral and/or renal tissue oxygen saturation before cardiopulmonary resuscitation was required...
March 16, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28301444/hemodynamic-and-cardiorespiratory-predictors-of-sport-rock-climbing-performance
#15
Simon Fryer, David Giles, Inmaculada Garrido Palomino, Alejandro de la O Puerta, Vanesa España Romero
Rock climbing performance has been suggested to involve a notable contribution from the aerobic metabolism. Previously it has been shown that forearm oxygenation kinetics can be used to distinguish ability groups and predict red-point sport climbing performance. Currently it is not known if forearm oxygenation kinetics, or a sport specific assessment of cardiorespiratory fitness best predicts sport rock climbing performance. The aim of the study was to determine whether forearm oxidative capacity index, maximal de-oxygenation (Δ score) during a treadwall V[Combining Dot Above]O[SUBSCRIPT TWO]peak test, treadwall V[Combining Dot Above]O[SUBSCRIPT TWO]peak, or running V[Combining Dot Above]O[SUBSCRIPT TWO]max best predicts self-reported sport climbing performance...
March 13, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28301015/influence-of-photoinitiator-system-on-physical-chemical-properties-of-experimental-self-adhesive-composites
#16
Marcus Vinicius Loureiro Bertolo, Rita de Cássia Martins Moraes, Carmem Pfeifer, Vinícius Esteves Salgado, Ana Rosa Costa Correr, Luis Felipe J Schneider
The aim of this study was to determine the influence of photoinitiator systems on physical-chemical properties of flowable composites. Conventional (CFC), composed by bisphenol-glycidyl dimethacrylate (BisGMA)+triethyleneglycol dimethacrylate (TEGDMA), and self-adhesive (SAFC), composed by BisGMA+TEDGMA+bis{2-(methacryloyloxy) ethyl} phosphate (2MP), flowable composites were developed. Five photoinitiator systems were tested: camphorquinone (CQ), ethyl-4-dimethylaminobenzoate (EDMAB), diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide (TPO), phenylbis (2,4,6-trimethylbenzoyl)phosphine oxide (BAPO), CQ+EDMAB+TPO and CQ+EDMAB+BAPO...
January 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28295013/impact-of-familial-loading-on-prefrontal-activation-in-major-psychiatric-disorders-a-near-infrared-spectroscopy-nirs-study
#17
Kazutaka Ohi, Takamitsu Shimada, Hiroaki Kihara, Toshiki Yasuyama, Kazuyuki Sawai, Yukihisa Matsuda, Kazuaki Oshima, Hiroaki Okubo, Yusuke Nitta, Takashi Uehara, Yasuhiro Kawasaki
Family history (FH) is predictive of the development of major psychiatric disorders (PSY). Familial psychiatric disorders are largely a consequence of genetic factors and typically exhibit more severe impairments. Decreased prefrontal activity during verbal fluency testing (VFT) may constitute an intermediate phenotype for PSY. We investigated whether familial PSY were associated with a greater severity of prefrontal dysfunction in accordance with genetic loading. We measured prefrontal activity during VFT using near-infrared spectroscopy (NIRS) in patients with schizophrenia (SCZ, n = 45), major depressive disorder (MDD, n = 26) or bipolar disorder (BIP, n = 22) and healthy controls (HC, n = 51)...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28294282/transient-increase-in-systemic-interferences-in-the-superficial-layer-and-its-influence-on-event-related-motor-tasks-a-functional-near-infrared-spectroscopy-study
#18
Isao Nambu, Takuya Ozawa, Takanori Sato, Takatsugu Aihara, Yusuke Fujiwara, Yohei Otaka, Rieko Osu, Jun Izawa, Yasuhiro Wada
No abstract text is available yet for this article.
March 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28293809/a-mesenteric-traction-syndrome-affects-near-infrared-spectroscopy-evaluated-cerebral-oxygenation-because-skin-blood-flow-increases
#19
Niels D Olesen, Henrik Sørensen, Rikard Ambrus, Lars B Svendsen, Anton Lund, Niels H Secher
During abdominal surgery manipulation of internal organs may induce a "mesenteric traction syndrome" (MTS) including a triad of flushing, hypotension, and tachycardia that lasts for about 30 min. We evaluated whether MTS affects near-infrared spectroscopy (NIRS) assessed frontal lobe oxygenation (ScO2) by an increase in forehead skin blood flow (SkBF). The study intended to include 10 patients who developed MTS during pancreaticoduodenectomy and 22 patients were enrolled (age 61 ± 8 years; mean ± SD)...
March 14, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28293062/near-infrared-spectroscopy-reveals-abnormal-hemodynamics-in-the-left-dorsolateral-prefrontal-cortex-of-menopausal-depression-patients
#20
Xiang-Yun Ma, Yong-Jun Wang, Bo Xu, Kun Feng, Gao-Xiang Sun, Xiao-Qian Zhang, Xiao-Min Liu, Chen-Yu Shen, Xia-Jin Ren, Jing-Jing Sun, Po-Zi Liu
Background/Objective. Menopausal depression (MD) is characterized by depressive symptoms along with hormonal fluctuations. We investigate brain function alteration between major depressive disorder (MDD) and MD. Methods. The difference in oxygenated hemoglobin (Oxy-Hb) for the prefrontal cortex (PFC) was compared retrospectively among 90 females presented with 30 MDD, 30 MD, and 30 healthy controls (HCs) using verbal fluency task (VFT) with near-infrared spectroscopy (NIRS). Results. We observed a significant difference in Oxy-Hb alteration in the left dorsolateral PFC (DLPFC) using VFT with NIRS (channel 18, P = 0...
2017: Disease Markers
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