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https://www.readbyqxmd.com/read/28216325/universal-influenza-virus-vaccines-and-therapeutic-antibodies
#1
REVIEW
Raffael Nachbagauer, Florian Krammer
BACKGROUND: Current influenza virus vaccines are effective when well matched to the circulating strains. Unfortunately, antigenic drift and the high diversity of potential emerging zoonotic and pandemic viruses make it difficult to select the right strains for vaccine production. This problem causes vaccine mismatches which lead to sharp drops in vaccine effectiveness and long response times in case of novel pandemic viruses. AIMS: To provide an overview of universal influenza virus vaccines and therapeutic antibodies in pre-clinical and clinical development...
February 12, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28215188/high-school-cardiac-emergency-response-plans-and-sudden-cardiac-death-in-the-young
#2
Michelle J White, Emefah C Loccoh, Monica M Goble, Sunkyung Yu, Folafoluwa O Odetola, Mark W Russell
: Introduction Sudden cardiac death (SCD) is responsible for 5%-10% of all deaths among children 5-19 years-of-age. The incidence of SCD in youth in Michigan (USA) and nationwide is higher in racial/ethnic minorities and in certain geographic areas. School cardiac emergency response plans (CERPs) increase survival after cardiac arrest. However, school cardiac emergency preparedness remains variable. Studying population-level factors associated with school cardiac emergency preparedness and incidence of SCD in the young may improve understanding of disparities in the incidence of SCD...
February 20, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28214468/difficulties-experienced-by-veterinarians-when-communicating-about-emerging-zoonotic-risks-with-animal-owners-the-case-of-hendra-virus
#3
Diana H Mendez, Petra Büttner, Jenny Kelly, Madeleine Nowak, Rick Speare Posthumously
BACKGROUND: Communication skills are essential for veterinarians who need to discuss animal health related matters with their clients. When dealing with an emerging zoonosis, such as Hendra virus (HeV), veterinarians also have a legal responsibility to inform their clients about the associated risks to human health. Here we report on part of a mixed methods study that examined the preparedness of, and difficulties experienced by, veterinarians communicating about HeV-related risks with their clients...
February 18, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28210860/a-heat-vulnerability-index-to-improve-urban-public-health-management-in-san-juan-puerto-rico
#4
Pablo Méndez-Lázaro, Frank E Muller-Karger, Daniel Otis, Matthew J McCarthy, Ernesto Rodríguez
Increased frequency and length of high heat episodes are leading to more cardiovascular issues and asthmatic responses among the population of San Juan, the capital of the island of Puerto Rico, USA. An urban heat island effect, which leads to foci of higher temperatures in some urban areas, can raise heat-related mortality. The objective of this research is to map the risk of high temperature in particular locations by creating heat maps of the city of San Juan. The heat vulnerability index (HVI) maps were developed using images collected by satellite-based remote sensing combined with census data...
February 17, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28198759/how-specialty-certification-influences-professional-practice
#5
Sharon Vanairsdale
Certified Nurses Day (March 19) honors nurses worldwide who contribute to better patient outcomes through board certification in their specialty. In this month's Magnet® Perspectives column, Sharon Vanairsdale, MS, APRN, ACNS-BC, NP-C, CEN, program director for Emory University Hospital's Serious Communicable Diseases Unit, discusses the value of certification, what it means to her professional practice, and how it helps to champion her work. Ms Vanairsdale is triple certified as a certified emergency nurse, an adult clinical nurse specialist, and an adult nurse practitioner...
March 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28192440/helicopter-emergency-medical-services-in-major-incident-management-a-national-norwegian-cross-sectional-survey
#6
Anne Siri Johnsen, Stephen J M Sollid, Trond Vigerust, Morten Jystad, Marius Rehn
OBJECTIVE: Helicopter Emergency Medical Services (HEMS) aim to bring a highly specialised crew to the scene of major incidents for triage, treatment and transport. We aim to describe experiences made by HEMS in Norway in the management of major incidents. DESIGN: Doctors, rescue paramedics and pilots working in Norwegian HEMS and Search and Rescue Helicopters (SAR) January 1st 2015 were invited to a cross-sectional study on experiences, preparedness and training in major incident management...
2017: PloS One
https://www.readbyqxmd.com/read/28192418/defining-the-antibody-cross-reactome-directed-against-the-influenza-virus-surface-glycoproteins
#7
Raffael Nachbagauer, Angela Choi, Ariana Hirsh, Irina Margine, Sayaka Iida, Aldo Barrera, Marcela Ferres, Randy A Albrecht, Adolfo García-Sastre, Nicole M Bouvier, Kimihito Ito, Rafael A Medina, Peter Palese, Florian Krammer
Infection with influenza virus induces antibodies to the viral surface glycoproteins hemagglutinin and neuraminidase, and these responses can be broadly protective. To assess the breadth and magnitude of antibody responses, we sequentially infected mice, guinea pigs and ferrets with divergent H1N1 or H3N2 subtypes of influenza virus. We measured antibody responses by ELISA of an extensive panel of recombinant glycoproteins representing the viral diversity in nature. Guinea pigs developed high titers of broadly cross-reactive antibodies; mice and ferrets exhibited narrower humoral responses...
February 13, 2017: Nature Immunology
https://www.readbyqxmd.com/read/28192055/a-community-checklist-for-health-sector-resilience-informed-by-hurricane-sandy
#8
Eric S Toner, Meghan McGinty, Monica Schoch-Spana, Dale A Rose, Matthew Watson, Erin Echols, Eric G Carbone
This is a checklist of actions for healthcare, public health, nongovernmental organizations, and private entities to use to strengthen the resilience of their community's health sector to disasters. It is informed by the experience of Hurricane Sandy in New York and New Jersey and analyzed in the context of findings from other recent natural disasters in the United States. The health sector is defined very broadly, including-in addition to hospitals, emergency medical services (EMS), and public health agencies-healthcare providers, outpatient clinics, long-term care facilities, home health providers, behavioral health providers, and correctional health services...
January 2017: Health Security
https://www.readbyqxmd.com/read/28185994/motivational-interviewing-to-improve-self-care-in-heart-failure-patients-motivate-hf-study-protocol-of-a-three-arm-multicenter-randomized-controlled-trial
#9
Ercole Vellone, Marco Paturzo, Fabio D'Agostino, Antonio Petruzzo, Stefano Masci, Davide Ausili, Paola Rebora, Rosaria Alvaro, Barbara Riegel
AIMS: Heart Failure (HF) self-care improves patient outcomes but trials designed to improve HF self-care have shown inconsistent results. Interventions may be more effective in improving self-care if they mobilize support from providers, promote self-efficacy, increase understanding of HF, increase the family involvement, and are individualized. All of these elements are emphasized in motivational interviewing (MI); few trials have been conducted using MI in HF patients and rarely have caregivers been involved in MI interventions...
February 7, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28182860/corrigendum
#10
(no author information available yet)
Wizner, K., Stradtman, L., Novak, D., and Shaffer, R. (2016). Prevalence of respiratory protective devices in U.S. healthcare facilities: implications for emergency preparedness. Workplace Health & Safety, 64(8):359-368. (Original DOI: 10.1177/2165079916657108 ).
February 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28182514/assessment-of-impact-and-recovery-needs-in-communities-affected-by-the-elk-river-chemical-spill-west-virginia-april-2014
#11
Sherry L Burrer, Ethan Fechter-Leggett, Tesfaye Bayleyegn, Miguella Mark-Carew, Carrie Thomas, Danae Bixler, Rebecca S Noe, Joy Hsu, Loretta Haddy, Amy Wolkin
OBJECTIVES: In January 2014, 4-methylcyclohexanemethanol spilled into the Elk River near Charleston, West Virginia, contaminating the water supply for about 120 000 households. The West Virginia American Water Company (WVAWC) issued a "do not use" water order for 9 counties. After the order was lifted (10 days after the spill), the communities' use of public water systems, information sources, alternative sources of water, and perceived impact of the spill on households were unclear to public health officials...
January 1, 2017: Public Health Reports
https://www.readbyqxmd.com/read/28179044/translating-battlefield-practices-to-disaster-health
#12
Kandra Strauss-Riggs, Kevin Yeskey, Aubrey Miller, Stacey Arnesen, Craig Goolsby
We review aspects of the recently released National Academies of Sciences, Engineering, and Medicine report A National Trauma Care System: Integrating Military and Civilian Trauma Systems to Achieve Zero Preventable Deaths After Injury most relevant to disaster health, particularly the concepts of focused empiricism and building a learning health system. The article references battlefield success utilizing these concepts and the emerging Disaster Research Response Program. We call upon disaster health researchers to apply the report's recommendations to their work...
February 9, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28179007/global-research-trends-of-world-health-organization-s-top-eight-emerging-pathogens
#13
Waleed M Sweileh
BACKGROUND: On December 8(th), 2015, World Health Organization published a priority list of eight pathogens expected to cause severe outbreaks in the near future. To better understand global research trends and characteristics of publications on these emerging pathogens, we carried out this bibliometric study hoping to contribute to global awareness and preparedness toward this topic. METHOD: Scopus database was searched for the following pathogens/infectious diseases: Ebola, Marburg, Lassa, Rift valley, Crimean-Congo, Nipah, Middle Eastern Respiratory Syndrome (MERS), and Severe Respiratory Acute Syndrome (SARS)...
February 8, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28178398/delphi-survey-of-clinical-nursing-and-midwifery-research-priorities-in-the-eastern-mediterranean-region
#14
Carolyn Sun, Jennifer Dohrn, Arwa Oweis, Huda Abu-Saad Huijer, Fathieh Abu-Moghli, Hania Dawani, Cheherezade Ghazi, Elaine Larson
PURPOSE: As the shortage of nurses and midwives is expected to worsen in the Eastern Mediterranean region concomitantly with a growing focus on achievement of universal health coverage, nurses and midwives are expected to fill major gaps in health care. Hence, the need for a solid evidence base for nursing practice and a clear direction for clinical nursing research are paramount. Therefore, a Delphi survey was conducted to determine clinical (research focused on patient outcomes) nursing and midwifery priorities for research within this region...
February 8, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28166176/applying-instructional-design-strategies-and-behavior-theory-to-household-disaster-preparedness-training
#15
Tracy N Thomas, Robyn K Sobelson, Corinne J Wigington, Alyson L Davis, Victoria H Harp, Michelle Leander-Griffith, Joan P Cioffi
CONTEXT: Interventions and media campaigns promoting household disaster preparedness have produced mixed results in affecting behaviors. In large part, this is due to the limited application of instructional design strategies and behavior theory, such as the Transtheoretical Model (TTM). This study describes the development and evaluation of Ready CDC, an intervention designed to increase household disaster preparedness among the Centers for Disease Control and Prevention (CDC) workforce...
February 3, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28159162/pandemic-and-avian-influenza-a-viruses-in-humans-epidemiology-virology-clinical-characteristics-and-treatment-strategy
#16
REVIEW
Hui Li, Bin Cao
The intermittent outbreak of pandemic influenza and emergence of novel avian influenza A virus is worldwide threat. Although most patients present with mild symptoms, some deteriorate to severe pneumonia and even death. Great progress in the understanding of the mechanism of disease pathogenesis and a series of vaccines has been promoted worldwide; however, incidence, morbidity, and mortality remains high. To step up vigilance and improve pandemic preparedness, this article elucidates the virology, epidemiology, pathogenesis, clinical characteristics, and treatment of human infections by influenza A viruses, with an emphasis on the influenza A(H1N1)pdm09, H5N1, and H7N9 subtypes...
March 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/28159021/ebola-outbreak-preparedness-planning-a-qualitative-study-of-clinicians-experiences
#17
J Broom, A Broom, V Bowden
OBJECTIVES: The 2014-15 Ebola outbreak in West Africa highlighted the challenges many hospitals face when preparing for the potential emergence of highly contagious diseases. This study examined the experiences of frontline health care professionals in an Australian hospital during the outbreak, with a focus on participant views on information, training and preparedness, to inform future outbreak preparedness planning. STUDY DESIGN: Semi-structured interviews were conducted with 21 healthcare professionals involved in Ebola preparedness planning, at a hospital in Australia...
February 2017: Public Health
https://www.readbyqxmd.com/read/28153680/facilitating-emergency-hospital-evacuation-through-uniform-discharge-criteria
#18
Sandra Keret, Meital Nahari, Ofer Merin, Limor Aharonson-Daniel, Sara Goldberg, Bruria Adini
BACKGROUND: Though hospitals' operational continuity is crucial, full institutional evacuation may at times be unavoidable. The study's objective was to establish criteria for discharge of patients during complete emergency evacuation and compare scope of patients suitable for discharge pre/post implementation of criteria. BASIC PROCEDURES: Standards for patient discharge during an evacuation were developed based on literature and disaster managers. The standards were reviewed in a two-round Delphi process...
December 31, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28153060/how-to-choose-using-the-delphi-method-to-develop-consensus-triggers-and-indicators-for-disaster-response
#19
Rebecca Lis, Vicki Sakata, Onora Lien
OBJECTIVE: To identify key decisions along the continuum of care (conventional, contingency, and crisis) and the critical triggers and data elements used to inform those decisions concerning public health and health care response during an emergency. METHODS: A classic Delphi method, a consensus-building survey technique, was used with clinicians around Washington State to identify regional triggers and indicators. Additionally, using a modified Delphi method, we combined a workshop and single-round survey with panelists from public health (state and local) and health care coalitions to identify consensus state-level triggers and indicators...
February 3, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28148338/psychological-correlates-of-civilian-preparedness-for-conflicts
#20
Moran Bodas, Maya Siman-Tov, Shulamith Kreitler, Kobi Peleg
OBJECTIVES: Preparedness for emergencies and disasters is imperative for public resilience. Previous studies have revealed low levels of civilian preparedness for conflicts. Classic behavioral models prove inapt in describing preparedness patterns in victimized populations chronically exposed to this threat. In an effort to expand this perspective, we hypothesized that other psychological constructs are correlated with preparedness. METHODS: A cross-sectional, Internet-based study was performed in Israel in early 2016...
February 2, 2017: Disaster Medicine and Public Health Preparedness
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