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"Oxygen uptake kinetics"

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https://www.readbyqxmd.com/read/29689123/the-role-of-onium-salts-in-the-pro-oxidant-effect-of-gold-nanoparticles-in-lipophilic-environments
#1
Andrea Baschieri, Benedetta Del Secco, Nelsi Zaccheroni, Luca Valgimigli, Riccardo Amorati
Metal nanoparticles are reported to be toxic due to free radical generation at their surface. Relatively inert thiol-capped gold nanoparticles (AuNPs) have been reported to induce radical formation in the presence of hydroperoxides, which would conflict with their potential use as inert scaffolds for the design of novel nano-antioxidants. With the aim of clarifying this aspect, we investigated the pro-oxidant activity of dodecanethiol-capped AuNPs (~5 nm), prepared via the Brust-Schiffrin synthesis, by oxygen-uptake kinetic studies...
April 24, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29662455/fitness-level-and-not-aging-per-se-determines-the-oxygen-uptake-kinetics-response
#2
Mitchell A George, Kaitlin M McLay, Patricia K Doyle-Baker, Raylene A Reimer, Juan M Murias
Although aging has been associated to slower [Formula: see text]O2 kinetics, some evidence indicates that fitness status and not aging per se might modulate this response. The main goal of this study was to examine the [Formula: see text]O2 , deoxygenated hemoglobin+myoglobin (deoxy-[Hb+Mb]) kinetics, and the NIRS-derived vascular reperfusion responses in older compared to young men of different training levels (i.e., inactive, recreationally active, and endurance trained). Ten young inactive [YI; 26 ± 5 yrs...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29541131/oxygen-delivery-is-not-a-limiting-factor-during-post-exercise-recovery-in-healthy-young-adults
#3
Robert T Mankowski, Victor M Niemeijer, Jasper P Jansen, Lotte Spraakman, Henk J Stam, Stephan F E Praet
Purpose: It is still equivocal whether oxygen uptake recovery kinetics are limited by oxygen delivery and can be improved by supplementary oxygen. The present study aimed to investigate whether measurements of muscle and pulmonary oxygen uptake kinetics can be used to assess oxygen delivery limitations in healthy subjects. Methods: Sixteen healthy young adults performed three sub-maximal exercise tests (6 min at 40% Wmax ) under hypoxic (14%O2 ), normoxic (21%O2 ) and hyperoxic (35%O2 ) conditions on separate days in randomized order...
June 2017: Journal of Exercise Science and Fitness
https://www.readbyqxmd.com/read/29517834/properties-of-the-vastus-lateralis-muscle-in-relation-to-age-and-physiological-function-in-master-cyclists-aged-55-79-years
#4
Ross D Pollock, Katie A O'Brien, Lorna J Daniels, Kathrine B Nielsen, Anthea Rowlerson, Niharika A Duggal, Norman R Lazarus, Janet M Lord, Andrew Philp, Stephen D R Harridge
In this study, results are reported from the analyses of vastus lateralis muscle biopsy samples obtained from a subset (n = 90) of 125 previously phenotyped, highly active male and female cyclists aged 55-79 years in regard to age. We then subsequently attempted to uncover associations between the findings in muscle and in vivo physiological functions. Muscle fibre type and composition (ATPase histochemistry), size (morphometry), capillary density (immunohistochemistry) and mitochondrial protein content (Western blot) in relation to age were determined in the biopsy specimens...
April 2018: Aging Cell
https://www.readbyqxmd.com/read/29394491/impact-of-l-citrulline-supplementation-on-oxygen-uptake-kinetics-during-walking
#5
John Ashley, Youngdeok Kim, Joaquin U Gonzales
Supplementation with L-citrulline (Cit) has been shown to improve muscle oxygenation and oxygen uptake (VO2) kinetics during moderate-to-high intensity cycling in young men. The aim of this study was to test the hypothesis whether Cit would improve VO2 kinetics during walking in older and young adults. In a randomized, double-blind study, 26 (15 women, 11 men) adults between the ages of 20-35y (n = 15) and 64-86y (n = 11) completed 7 day periods of taking placebo and L-citrulline (6 g/day) in a crossover manner...
February 2, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29279000/oxygen-uptake-on-kinetics-during-six-minute-walk-test-predicts-short-term-outcomes-after-off-pump-coronary-artery-bypass-surgery
#6
Isadora Salvador Rocco, Marcela Viceconte, Hayanne Osiro Pauletti, Bruna Caroline Matos-Garcia, Natasha Oliveira Marcondi, Caroline Bublitz, Douglas William Bolzan, Rita Simone Lopes Moreira, Michel Silva Reis, Nelson Américo Hossne, Walter José Gomes, Ross Arena, Solange Guizilini
PURPOSE: We aimed to investigate the ability of oxygen uptake kinetics to predict short-term outcomes after off-pump coronary artery bypass grafting. METHODS: Fifty-two patients aged 60.9 ± 7.8 years waiting for off-pump coronary artery bypass surgery were evaluated. The 6-min walk test distance was performed pre-operatively, while simultaneously using a portable cardiopulmonary testing device. The transition of oxygen uptake kinetics from rest to exercise was recorded to calculate oxygen uptake kinetics fitting a monoexponential regression model...
December 26, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29250707/non-invasive-estimation-of-muscle-oxygen-uptake-kinetics-with-pseudorandom-binary-sequence-and-step-exercise-responses
#7
Uwe Drescher, R Schmale, J Koschate, L Thieschäfer, T Schiffer, S Schneider, U Hoffmann
PURPOSE: The aim of the study was to test for significant differences in non-invasively estimated muscle oxygen uptake ([Formula: see text]) kinetics, assessed by a square-wave exercise protocol (STEP) as well as by a time series approach with pseudorandom binary sequence (PRBS) work rate (WR) changes. METHODS: Seventeen healthy and active individuals (10 women, 7 men; 23 ± 2 years old; height 175 ± 11 cm; body mass 73 ± 14 kg [mean ± SD]) completed five repetitions of WR transitions from 30 to 80 W for the STEP approach and two sequences of pseudorandom binary WR changes between 30 and 80 W for the PRBS approach...
February 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29074573/reply-to-francescato-et-al-interpreting-the-averaging-methods-to-estimate-oxygen-uptake-kinetics-parameters
#8
Alan P Benson, T Scott Bowen, Carrie Ferguson, Scott R Murgatroyd, Harry B Rossiter
No abstract text is available yet for this article.
October 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29024783/oxygen-uptake-kinetics-following-six-weeks-of-interval-and-continuous-endurance-exercise-training-an-explorative-pilot-study
#9
U Drescher, T Schefter, J Koschate, T Schiffer, K Brixius, S Schneider, U Hoffmann
PURPOSE: The aim of the study was to compare the responses of pulmonary (V˙O2pulm) and muscle (V˙O2musc) oxygen uptake kinetics before (PRE) and after (POST) six weeks of endurance exercise training. METHODS: Nine untrained individuals performed pseudo-random binary sequences work rate changes between 30W and 80W at PRE and POST training intervention. Heart rate (HR) and V˙O2pulm were measured beat-to-beat and breath-by-breath, respectively. V˙O2musc was estimated applying the approach of Hoffmann et al...
October 9, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28919863/oxygen-uptake-kinetics-is-slower-in-swimming-than-arm-cranking-and-cycling-during-heavy-intensity
#10
Ana Sousa, Fabio Borrani, Ferran A Rodríguez, Grégoire P Millet
Oxygen uptake ([Formula: see text]) kinetics has been reported to be influenced by the activity mode. However, only few studies have compared [Formula: see text]O2 kinetics between activities in the same subjects in which they were equally trained. Therefore, this study compared the [Formula: see text]O2 kinetics response to swimming, arm cranking, and cycling within the same group of subjects within the heavy exercise intensity domain. Ten trained male triathletes (age 23.2 ± 4.5 years; height 180.8 ± 8...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28750180/association-between-inspiratory-muscle-weakness-and-slowed-oxygen-uptake-kinetics-in-patients-with-chronic-obstructive-pulmonary-disease
#11
Andiara Wolpat, Francisco V Lima, Fabiola M Silva, Micheli Tochetto, Andressa de Freitas, Tatiane Grandi, Leonardo Rodrigues, Verônica Paiva, Gerson Cipriano, Adriana M Chiappa, Julio Zago, Gaspar R Chiappa
Patients with chronic obstructive pulmonary disease (COPD) may have poor inspiratory muscle function, which reduces minute and alveolar ventilation, leading to increased hypoxemia and slow pulmonary oxygen uptake kinetics. However, little is known about the effect of inspiratory muscle weakness (IMW) on oxygen uptake kinetics in patients with COPD. Thus, we tested the hypothesis that COPD patients with IMW have slowed oxygen uptake kinetics. An observational study was conducted that included COPD patients with moderate to severe airflow limitation and a history of intolerance to exercise...
December 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28627041/prior-exercise-speeds-pulmonary-oxygen-uptake-kinetics-and-increases-critical-power-during-supine-but-not-upright-cycling
#12
Richie P Goulding, Denise M Roche, Simon Marwood
What is the central question of this study? Critical power (CP) represents the highest work rate for which a metabolic steady state is attainable. The physiological determinants of CP are unclear, but research suggests that CP might be related to the time constant of phase II oxygen uptake kinetics (τV̇O2). What is the main finding and its importance? We provide the first evidence that τV̇O2 is mechanistically related to CP. A reduction of τV̇O2 in the supine position was observed alongside a concomitant increase in CP...
June 19, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28561192/heart-rate-and-oxygen-uptake-kinetics-in-type-2-diabetes-patients-a-pilot-study-on-the-influence-of-cardiovascular-medication-on-regulatory-processes
#13
RANDOMIZED CONTROLLED TRIAL
Jessica Koschate, Uwe Drescher, Klaus Baum, Christian Brinkmann, Thorsten Schiffer, Joachim Latsch, Klara Brixius, Uwe Hoffmann
The aim of this pilot study was to investigate whether there are differences in heart rate and oxygen uptake kinetics in type 2 diabetes patients, considering their cardiovascular medication. It was hypothesized that cardiovascular medication would affect heart rate and oxygen uptake kinetics and that this could be detected using a standardized exercise test. 18 subjects were tested for maximal oxygen uptake. Kinetics were measured in a single test session with standardized, randomized moderate-intensity work rate changes...
May 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28530476/time-trials-versus-time-to-exhaustion-tests-effects-on-critical-power-w-and-oxygen-uptake-kinetics
#14
Bettina Karsten, Jonathan Baker, Fernando Naclerio, Andreas Klose, Antonino Bianco, Alfred Nimmerichter
PURPOSE: To investigate single-day time-to-exhaustion (TTE) and time-trial (TT) -based laboratory tests values of critical power (CP), W prime (W'), and respective oxygen-uptake-kinetic responses. METHODS: Twelve cyclists performed a maximal ramp test followed by 3 TTE and 3 TT efforts interspersed by 60 min recovery between efforts. Oxygen uptake ( V ˙ O 2 ) was measured during all trials. The mean response time was calculated as a description of the overall [Formula: see text]-kinetic response from the onset to 2 min of exercise...
February 1, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28450551/data-collection-handling-and-fitting-strategies-to-optimize-accuracy-and-precision-of-oxygen-uptake-kinetics-estimation-from-breath-by-breath-measurements
#15
Alan P Benson, T Scott Bowen, Carrie Ferguson, Scott R Murgatroyd, Harry B Rossiter
Phase 2 pulmonary oxygen uptake kinetics (ϕ2 τVO2P) reflect muscle oxygen consumption dynamics and are sensitive to changes in state of training or health. This study identified an unbiased method for data collection, handling and fitting to optimize VO2P kinetics estimation. A validated computational model of VO2P kinetics and a Monte Carlo approach simulated 2 x 10(5) moderate intensity transitions using a distribution of metabolic and circulatory parameters spanning normal health. Effects of averaging (interpolation, binning, stacking or separate fitting of up to 10 transitions) and fitting procedures (bi-exponential fitting, or ϕ2 isolation by time removal, statistical or derivative methods followed by mono-exponential fitting) on accuracy and precision of ϕ2 τVO2P estimation were assessed...
April 27, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28357580/the-relationship-between-oxygen-uptake-kinetics-and-neuromuscular-fatigue-in-high-intensity-cycling-exercise
#16
John Temesi, Felipe Mattioni Maturana, Arthur Peyrard, Tatiane Piucco, Juan M Murias, Guillaume Y Millet
PURPOSE: In theory, a slow oxygen uptake ([Formula: see text]) kinetics leads to a greater accumulation of anaerobic by-products, which can, in turn, induce more neuromuscular fatigue. However, the existence of this relationship has never been tested. METHODS: After two sessions to measure peak [Formula: see text], peak power output (POpeak), and [Formula: see text] kinetics responses in the unfatigued state (τ [Formula: see text] MOD), 10 healthy young adults performed a 6-min cycling bout at 80% POpeak (INT6-min)...
May 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28274780/analysis-of-heart-rate-and-oxygen-uptake-kinetics-studied-by-two-different-pseudo-random-binary-sequence-work-rate-amplitudes
#17
U Drescher, J Koschate, T Schiffer, S Schneider, U Hoffmann
PURPOSE: The aim of the study was to compare the kinetics responses of heart rate (HR), pulmonary (V˙O2 pulm) and predicted muscular (V˙O2 musc) oxygen uptake between two different pseudo-random binary sequence (PRBS) work rate (WR) amplitudes both below anaerobic threshold. METHODS: Eight healthy individuals performed two PRBS WR protocols implying changes between 30W and 80W and between 30W and 110W. HR and V˙O2 pulm were measured beat-to-beat and breath-by-breath, respectively...
June 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28245246/oxygen-uptake-kinetics-and-energy-system-s-contribution-around-maximal-lactate-steady-state-swimming-intensity
#18
Jailton Gregório Pelarigo, Leandro Machado, Ricardo Jorge Fernandes, Camila Coelho Greco, João Paulo Vilas-Boas
The purpose of this study was to examine the oxygen uptake ([Formula: see text]) kinetics and the energy systems' contribution at 97.5, 100 and 102.5% of the maximal lactate steady state (MLSS) swimming intensity. Ten elite female swimmers performed three-to-five 30 min submaximal constant swimming bouts at imposed paces for the determination of the swimming velocity (v) at 100%MLSS based on a 7 x 200 m intermittent incremental protocol until voluntary exhaustion to find the v associated at the individual anaerobic threshold...
2017: PloS One
https://www.readbyqxmd.com/read/28239356/sex-and-exercise-intensity-do-not-influence-oxygen-uptake-kinetics-in-submaximal-swimming
#19
Joana F Reis, Gregoire P Millet, Paula M Bruno, Veronica Vleck, Francisco B Alves
The aim of this study was to compare the oxygen uptake ([Formula: see text]) kinetics in front crawl between male and female swimmers at moderate and heavy intensity. We hypothesized that the time constant for the primary phase [Formula: see text] kinetics was faster in men than in women, for both intensities. Nineteen well trained swimmers (8 females mean ± SD; age 17.9 ± 3.5 years; mass 55.2 ± 3.6 kg; height 1.66 ± 0.05 m and 11 male 21.9 ± 2.8 years; 78.2 ± 11.1 kg; 1.81 ± 0.08 m) performed a discontinuous maximal incremental test and two 600-m square wave transitions for both moderate and heavy intensities to determine the [Formula: see text] kinetics parameters using mono- and bi-exponential models, respectively...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28215595/gas-exchange-kinetics-following-concentric-eccentric-isokinetic-arm-and-leg-exercise
#20
U Drescher, S Mookerjee, A Steegmanns, A Knicker, U Hoffmann
PURPOSE: To evaluate the effects of exercise velocity (60, 150, 240deg∙s-1 ) and muscle mass (arm vs leg) on changes in gas exchange and arterio-venous oxygen content difference (avDO2 ) following high-intensity concentric-eccentric isokinetic exercise. METHODS: Fourteen subjects (26.9±3.1years) performed a 3×20-repetition isokinetic exercise protocol. Recovery beat-to-beat cardiac output (CO) and breath-by-breath gas exchange were recorded to determine post-exercise half-time (t1/2 ) for oxygen uptake (V˙O2 pulm), carbon dioxide output (V˙CO2 pulm), and ventilation (V˙E )...
June 2017: Respiratory Physiology & Neurobiology
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