keyword
MENU ▼
Read by QxMD icon Read
search

Black cumin

keyword
https://www.readbyqxmd.com/read/29223554/oral-administration-of-nigella-sativa-oil-and-thymoquinone-attenuates-long-term-cisplatin-treatment-induced-toxicity-and-oxidative-damage-in-rat-kidney
#1
Zeba Farooqui, Faaiza Shahid, Aijaz Ahmed Khan, Farah Khan
Cisplatin (CP) is an effective anti-cancer drug which causes remarkable toxicity to the kidney, particularly to proximal tubules, by generating reactive oxygen species. Nigella sativa (NS), commonly known as "black cumin" reduces the progression of various kidney disorders. Thymoquinone (TQ), the major bioactive constituent of NS seeds, has been credited for various pharmacological effects of NS. Since, a typical clinical CP dosing regimen involves CP administration in multiple cycles over a long time duration, hence the present study aimed to evaluate the renoprotective efficacy of NS oil and TQ against multiple dose CP treatment induced deleterious biochemical and histological alterations in rat kidney...
December 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29203114/a-simultaneous-screening-and-quantitative-method-for-the-multiresidue-analysis-of-pesticides-in-spices-using-ultra-high-performance-liquid-chromatography-high-resolution-orbitrap-mass-spectrometry
#2
Arnab Goon, Zareen Khan, Dasharath Oulkar, Raviraj Shinde, Suresh Gaikwad, Kaushik Banerjee
A novel screening and quantitation method is reported for non-target multiresidue analysis of pesticides using ultra-HPLC-quadrupole-Orbitrap mass spectrometry in spice matrices, including black pepper, cardamom, chili, coriander, cumin, and turmeric. The method involved sequential full-scan (resolution = 70,000), and variable data independent acquisition (vDIA) with nine consecutive fragmentation events (resolution = 17,500). Samples were extracted by the QuEChERS method. The introduction of an SPE-based clean-up step through hydrophilic-lipophilic-balance (HLB) cartridges proved advantageous in minimizing the false negatives...
November 29, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29200724/bioassay-guided-isolation-of-neuroprotective-fatty-acids-from-nigella-sativa-against-1-methyl-4-phenylpyridinium-induced-neurotoxicity
#3
Leila Hosseinzadeh, Hoda Monaghash, Farahnaz Ahmadi, Nastaran Ghiasvand, Yalda Shokoohinia
Objective: Parkinson's disease, a slowly progressive neurological disease, is associated with degeneration of the basal ganglia of the brain and a deficiency of the neurotransmitter dopamine. The main aspects of researches are the protection of normal neurons against degeneration. Fatty acids (FAs), the key structural elements of dietary lipids, are carboxylic straight chains and notable parameters in nutritional and industrial usefulness of a plant. Materials and Methods: Black cumin, a popular anti-inflammatory and antioxidant food seasoning, contains nonpolar constituents such as FAs which were extracted using hexane...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29196013/the-potential-of-herbs-and-spices-to-reduce-lipid-oxidation-during-heating-and-gastrointestinal-digestion-of-a-beef-product
#4
T Van Hecke, P L Ho, S Goethals, S De Smet
Here we tested the potential of ten culinary herbs (basil, oregano, rosemary and thyme) and spices (black pepper, cayenne pepper, cumin, curcuma, garlic and sweet paprika) to limit oxidation during cooking of a high-fat beef product, and during its subsequent in vitro gastrointestinal digestion. The herbs and spices were added separately at 0.5% and 1% (w/w), either during meat processing before heating of the product or after heating of the meat as a seasoning. Lipid oxidation was evaluated by malondialdehyde, 4-hydroxy-2-nonenal and hexanal quantification in the meat products and gastrointestinal digests...
December 2017: Food Research International
https://www.readbyqxmd.com/read/29178169/authentication-of-commercial-spices-based-on-the-similarities-between-gas-chromatographic-fingerprints
#5
Takaya Matsushita, JingJing Zhao, Noriyuki Igura, Mitsuya Shimoda
BACKGROUND: A simple and solvent-free method was developed for the authentication of commercial spices. The similarities between gas chromatographic fingerprints were measured using similarity indices and multivariate data analyses, as morphological differentiation between dried powders and small spice particles was challenging. The volatile compounds present in 11 spices (i.e., allspice, anise, black pepper, caraway, clove, coriander, cumin, dill, fennel, star anise, and white pepper) were extracted by headspace solid-phase microextraction, and analyzed by gas chromatography-mass spectrometry...
November 27, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29175783/total-antioxidant-capacity-of-commonly-used-fruits-vegetables-herbs-and-spices-of-pakistan
#6
Mobasher Ali Abid, Muhammad Ashfaq, Muhammad Junaid Hassan Sharif, Khalid Rauf, Wajahat Mahmood, Ikarmullah Khan, Ghulam Abbas
The current study was aimed at investigating the total antioxidant activity (TAC) of various fruits, vegetables, herbs and spices habitat in Pakistan. The ferric reducing ability of plasma (FRAP) assay was used to measure the TAC of various extracts (aqueous, ethanolic and aqueous-ethanolic). Following is the potency order for fruits (guava >strawberry >Pomegranate >apple >kinnow >melon >lemon >banana), vegetables (spinach >Cabbage (Purple) >Jalapeno >Radish >Brinjal >Bell Pepper >Lettuce >Carrot >Cabbage (White) >Onion >Potato >Tomato >Cucumber) and herbs/spices (clove >Rosemary >Thyme >Oregano >Cinnamon >Cumin >Kalonji >Paprika >Neem (Flower) >Fennel >Black Cardamom >Turmeric >Coriander >Ginger >Garlic)...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29172688/effect-of-nanoparticle-treatment-on-expression-of-a-key-gene-involved-in-thymoquinone-biosynthetic-pathway-in-nigella-sativa-l
#7
Mir Mohammad Hassan Kahila, Amin Mahdi Najy, Mahdi Rahaie, Mohammad Mir-Derikvand
Thymoquinone is the most important secondary metabolite in black Cumin, which has several pharmaceutical applications. In this study, effect of TiO2 and SiO2 nanoparticles as new elicitors, on expression of Geranyl diphosphate synthase gene (GPPS gene), as a key gene involved in thymoquione biosynthesis pathway was investigated in two Iranian accessions. Plants were treatment in the early flowering stage and after 24 h of 50 and 100 mg/L of each nanoparticle, separately. After RNA extraction, GPPS gene expression was analysed by qRT-PCR method...
November 27, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29079983/improving-growth-performance-and-health-status-of-meat-type-quail-by-supplementing-the-diet-with-black-cumin-cold-pressed-oil-as-a-natural-alternative-for-antibiotics
#8
Mohamed E Abd El-Hack, Samir A Mahgoub, Mohamed M A Hussein, Islam M Saadeldin
Using antibiotics in poultry diets as growth promoters was reported to have harmful effects on consumers, so the current study was done to monitor the impact of dietary supplementation of antimicrobial black cumin oil (BCO) on carcass traits, growth performance, biochemical components, and ileal microbial populations of growing Japanese quails. Three hundred growing Japanese quails were used with three different treatments (0, 0.50, and 1.0 g BCO/g diet). Birds fed diet supplemented with 0.5 g BCO/kg diet showed significant increase in body weight comparing with the control and other treatment group...
October 27, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29039041/evaluation-of-antioxidant-potential-of-essential-oils-of-some-commonly-used-indian-spices-in-in-vitro-models-and-in-food-supplements-enriched-with-omega-6-and-omega-3-fatty-acids
#9
Anwesa Bag, Rabi Ranjan Chattopadhyay
The aim of this study was to evaluate and compare the antioxidant potential of essential oils of some commonly used Indian spices (black pepper, cinnamon, clove, coriander and cumin) in various in vitro models and in food supplements enriched with omega-6 and omega-3 fatty acids. In vitro antioxidant potential was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging and Fe(2+) ion-chelating methods and lipid oxidation stabilisation potential was evaluated in bulk soybean oil-fish oil mixture and their oil-in-water emulsions using peroxide value (PV), p-anisidine value (p-AV) and total oxidation value as indicators of oxidation...
October 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29027705/effects-of-dietary-supplementation-of-spices-on-forage-degradability-ruminal-fermentation-in-vivo-digestibility-growth-performance-and-nitrogen-balance-in-black-bengal-goat
#10
M R Chowdhury, M M H Khan, S U Mahfuz, M A Baset
The objective of the study was to evaluate the effects of spices on forage utilization and nitrogen (N) emission using in vitro and in vivo approach. A 6 × 5 factorial triplicate arrangement was used to assess the in vitro degradability of rice straw with control (without spices) and individual (40 mg/g rice straw) spices (cumin, coriander, clove, black cumin, turmeric) at five different incubation times. In vitro dry matter (DM) and organic matter (OM) degradability of rice straw were highest in presence of spices except for clove...
October 13, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28988684/a-potent-nutraceutical-combination-of-cinnamomum-cassia-nigella-sativa-for-type-1-diabetes-mellitus
#11
Ginpreet Kaur, Mihir Invally, Mohammed Kamil Khan, Priyanka Jadhav
BACKGROUND: Nigella sativa (black cumin) and Cinnamomum cassia (Cinnamon) are an integral part of the Indian diet, and have also been sourced in the ayurveda, the traditional Indian system of medicine, for their medicinal properties. Both the herbs individually have been successfully evaluated for their preliminary antidiabetic potential. AIM: Herein, we dived deeper into antidiabetic properties of these herbs, by investigating the combinatorial effect of both herbs, on parameters of diabetes and further, as an adjunct to metformin therapy, for assessing the pharmacodynamics of herb-drug interaction in diabetes mellitus...
October 5, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28983249/therapeutic-potential-and-pharmaceutical-development-of-thymoquinone-a-multitargeted-molecule-of-natural-origin
#12
REVIEW
Sameer N Goyal, Chaitali P Prajapati, Prashant R Gore, Chandragouda R Patil, Umesh B Mahajan, Charu Sharma, Sandhya P Talla, Shreesh K Ojha
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known as black cumin or black seed and belongs to the family Ranunculaceae. A large number of studies have revealed that thymoquinone is the major active constituent in N. sativa oil this constituent is responsible for the majority of the pharmacological properties. The beneficial organoprotective activities of thymoquinone in experimental animal models of different human diseases are attributed to the potent anti-oxidant and anti-inflammatory properties...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28981375/prevalence-of-salmonella-in-11-spices-offered-for-sale-from-retail-establishments-and-in-imported-shipments-offered-for-entry-to-the-united-states
#13
Guodong Zhang, Lijun Hu, Régis Pouillot, Aparna Tatavarthy, Jane M Van Doren, Daria Kleinmeier, George C Ziobro, David Melka, Hua Wang, Eric W Brown, Errol Strain, Vincent K Bunning, Steven M Musser, Thomas S Hammack
The U.S. Food and Drug Administration conducted a survey to evaluate Salmonella prevalence and aerobic plate counts in packaged (dried) spices offered for sale at retail establishments in the United States. The study included 7,250 retail samples of 11 spice types that were collected during November 2013 to September 2014 and October 2014 to March 2015. No Salmonella-positive samples (based on analysis of 125 g) were found among retail samples of cumin seed (whole or ground), sesame seed (whole, not roasted or toasted, and not black), and white pepper (ground or cracked), for prevalence estimates of 0...
October 4, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28974821/formulation-characterization-and-antimicrobial-properties-of-black-cumin-essential-oil-nanoemulsions-stabilized-by-osa-starch
#14
Hafiz Rizwan Sharif, Shabbar Abbas, Hamid Majeed, Waseem Safdar, Muhammad Shamoon, Muhammad Aslam Khan, Muhammad Shoaib, Husnain Raza, Junaid Haider
Preparation of oil-in-water nanoemulsions has emerged as a subject of interest for the encapsulation of lipophilic functional ingredients to increase their stability and activity. In this study, black cumin essential oil nanoemulsions (BCO-NE) using different ratios of essential oil with canola and flax seed oils (ripening inhibitors) were formulated and stabilized with octenyl succinic anhydride (OSA) modified waxy maize starch. The nanoemulsions exhibited monomodal size distributions with mean droplet diameter below 200 nm and zeta potential above -30, indicating a strong electrostatic repulsion between the dispersed oil droplets...
September 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28938193/protective-effect-of-thymoquinone-against-diazinon-induced-hematotoxicity-genotoxicity-and-immunotoxicity-in-rats
#15
Gholam Hassan Danaei, Mohammad Karami
Several studies have shown that oxidative stress and cell damage can occur in the very early stages of diazinon (DZN) exposure. The present study was designed to determine the beneficial effect of thymoquinone (Thy), the main component of Nigella sativa (black seed or black cumin) against DZN immunotoxicity, hematotoxicity and genotoxicity in rats. In the present experimental study, 48 male Wistar rats were randomly divided into six groups, (eight per group) as follows: control (receiving corn oil as the DZN solvent), DZN (20mg/kg), Thy (10mg/kg), Thy (2...
September 7, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28917744/differentiation-of-cumin-seeds-using-a-metal-oxide-based-gas-sensor-array-in-tandem-with-chemometric-tools
#16
Mahdi Ghasemi-Varnamkhasti, Zahra Safari Amiri, Mojtaba Tohidi, Majid Dowlati, Seyed Saeid Mohtasebi, Adenilton C Silva, David D S Fernandes, Mário C U Araujo
Cumin is a plant of the Apiaceae family (umbelliferae) which has been used since ancient times as a medicinal plant and as a spice. The difference in the percentage of aromatic compounds in cumin obtained from different locations has led to differentiation of some species of cumin from other species. The quality and price of cumin vary according to the specie and may be an incentive for the adulteration of high value samples with low quality cultivars. An electronic nose simulates the human olfactory sense by using an array of sensors to distinguish complex smells...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28892789/thymoquinone-rich-fraction-nanoemulsion-tqrfne-decreases-a%C3%AE-40-and-a%C3%AE-42-levels-by-modulating-app-processing-up-regulating-ide-and-lrp1-and-down-regulating-bace1-and-rage-in-response-to-high-fat-cholesterol-diet-induced-rats
#17
Norsharina Ismail, Maznah Ismail, Nur Hanisah Azmi, Muhammad Firdaus Abu Bakar, Zhang Yida, Maizaton Atmadini Abdullah, Hamidon Basri
Though the causes of Alzheimer's disease (AD) are yet to be understood, much evidence has suggested that excessive amyloid-β (Aβ) accumulation due to abnormal amyloid-β precursor protein (APP) processing and Aβ metabolism are crucial processes towards AD pathogenesis. Hence, approaches aiming at APP processing and Aβ metabolism are currently being actively pursued for the management of AD. Studies suggest that high cholesterol and a high fat diet have harmful effects on cognitive function and may instigate the commencement of AD pathogenesis...
November 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28881699/thymoquinone-as-an-anticancer-molecule-from-basic-research-to-clinical-investigation
#18
REVIEW
Md Asaduzzaman Khan, Mousumi Tania, Shangyi Fu, Junjiang Fu
Thymoquinone is an anticancer phytochemical commonly found in black cumin. In this review, we discuss the potential of thymoquinone as anticancer molecule, its mechanism of action and future usage in clinical applications. Thymoquinone exhibits anticancer activity via numerous mechanisms of action, specifically by showing selective antioxidant and oxidant activity, interfering with DNA structure, affecting carcinogenic signaling molecules/pathways and immunomodulation. In vitro activity of thymoquinone has been further implicated in animal models of cancer; however, no clinical application has been proven yet...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28833158/plant-growth-promoting-bacteria-elevate-the-nutritional-and-functional-properties-of-black-cumin-and-flaxseed-fixed-oil
#19
Snežana Dimitrijević, Marija Pavlović, Svetolik Maksimovic, Mihajlo Ristić, Vladimir Filipović, Dušan Antonović, Suzana Dimitrijević-Branković
BACKGROUND: In order to study the influence of plant growth promoting bacteria (PGPB) belonging to the Streptomyces sp., Paenibacillus sp. and Hymenibacter sp, on fixed oil content of Flaxseed as well as Black cumin, a two years' field experiments were conducted. The PGPB was applied during seedtime of plants. The extraction of oil from seeds was performed with a CO2 supercritical extraction. RESULTS: The addition of PGPB significantly increase the content of C18:1 (from 16...
August 21, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28791082/protective-effect-of-nigella-sativa-oil-on-acoustic-trauma-induced-hearing-loss-in-rats
#20
Belde Culhaoglu, Selim S Erbek, Seyra Erbek, Evren Hizal
Acoustic trauma is a common reason for hearing loss. Different agents are used to prevent the harmful effect of acoustic trauma on hearing. The aim of this study was to evaluate the potential preventive effect of Nigella sativa (black cumin) oil in acoustic trauma. Our experimental study was conducted with 20 Sprague Downey female rats (mean age, 12 months; mean weight 250 g). All of the procedures were held under general anesthesia. Following otoscopic examinations, baseline-hearing thresholds were obtained using auditory brainstem responses (ABR)...
July 18, 2017: Audiology Research
keyword
keyword
76003
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"