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Black cumin

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https://www.readbyqxmd.com/read/29882119/evaluation-of-arsenic-cadmium-nickel-and-lead-in-common-spices-in-pakistan
#1
Jameel Ahmed Baig, Saba Bhatti, Tasneem Gul Kazi, Hassan Imran Afridi
The quantitative assessments and daily intake of arsenic (As), cadmium (Cd), nickel (Ni) and lead (Pb) were conducted in the 26 common spices collected from the market of Hyderabad, Pakistan. Conventional acid digestion procedure was applied for dissolution of common spices and the contents of toxic elemental were determined by graphite furnace atomic absorption spectrometry. The conventional acid digestion method was validated by certified reference materials and standard addition. A wide variability was observed in the levels of toxic elements in common spices...
June 7, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29879835/growth-carcass-traits-cecal-microbial-counts-and-blood-chemistry-of-meat-type-quail-fed-diets-supplemented-with-humic-acid-and-black-cumin-seeds
#2
Muhammad Arif, Abdur Rehman, Mohamed Ezzat Abd El-Hack, Muhammad Saeed, Fateh Khan, Muhammad Akhtar, Ayman A Swelum, Islam M Saadeldin, Abdullah N Alowaimer
Objective: The present study attempted to determine an alternative to antibiotics in poultry feeding. Methods: A total of 520 seven-day-old quail chicks were randomly allotted to eight treatment groups in a completely randomized design to evaluate the effect of different levels of humic acid (HA) and black cumin (BC) seed on growth, carcass traits, gut microbes, and blood chemistry of growing quails. Treatment groups were: (1) T1: control diet; (2) T2: basal diet + 5 g BC; (3) T3: basal diet + 0...
May 31, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29864536/physicochemical-properties-of-water-soluble-polysaccharides-from-black-cumin-seeds
#3
Ines Trigui, Héla Yaich, Assaâd Sila, Salma Cheikh-Rouhou, Ali Bougatef, Christophe Blecker, Hamadi Attia, M A Ayadi
In the present work, water-soluble polysaccharides were isolated from black cumin seeds. Polysaccharides were characterized by their carbohydrate composition, molecular weight, thermal stability and by FTIR, NMR spectroscopy and X-ray diffraction. The surface, the functional and the antioxidant properties of black cumin water-soluble polysaccharides (BCWSP) were also investigated. BCWSP consisted mainly of galacturonic acid (30.20%), glucuronic acid (17.66%) and neutral sugar (22.99%). BCWSP was composed of high peak molecular weight...
June 1, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29751576/thymoquinone-suppresses-irf-3-mediated-expression-of-type-i-interferons-via-suppression-of-tbk1
#4
Nur Aziz, Young-Jin Son, Jae Youl Cho
Interferon regulatory factor (IRF)-3 is known to have a critical role in viral and bacterial innate immune responses by regulating the production of type I interferon (IFN). Thymoquinone (TQ) is a compound derived from black cumin ( Nigella sativa L.) and is known to regulate immune responses by affecting transcription factors associated with inflammation, including nuclear factor-κB (NF-κB) and activator protein-1 (AP-1). However, the role of TQ in the IRF-3 signaling pathway has not been elucidated...
May 3, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29725229/some-properties-of-fresh-and-ripened-traditional-akcakatik-cheese
#5
Şimşek Bedia, Tuncer Yasin
Akcakatik cheese (yogurt cheese) is produced by drying strained yogurt with or without adding cloves or black cumin. The main objective of this study was to detect the properties of both fresh and ripened Akcakatik cheeses and to compare them. For this purpose the biogenic amine content, volatile flavor compounds, protein degradation level, chemical properties and some microbiological properties of 15 Akcakatik cheese samples were investigated. Titratable acidity, total dry matter, NaCl, total nitrogen, water soluble nitrogen, ripened index, histamine, diacetyl and acetaldehyde levels were found to be higher in ripened cheese samples than in fresh cheese samples...
February 2018: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/29705470/investigation-of-the-effect-of-black-cumin-oil-on-pain-in-osteoarthritis-geriatric-individuals
#6
Halil Ibrahim Tuna, Burcu Babadag, Ayse Ozkaraman, Guler Balci Alparslan
PURPOSE: This study has been carried out to investigate the analgesic effect of black cumin oil on individuals with knee pain. METHOD: The experimental group (n = 30) and control group (n = 30) have been randomly selected. The control group patients have continued their routine prescription. For the experimental group, black cumin oil has been applied by rubbing to their knees 3 times a week for 1 month. FINDINGS: As a result of the study, the mean VAS values of the patients in the experimental group has changed to 7...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29705440/the-association-between-quality-of-life-and-complementary-and-alternative-medicine-use-in-patients-with-diabetes-mellitus
#7
Ali Candar, Hakan Demirci, Ayse Karalar Baran, Yakup Akpınar
AIM: In the current study, we aimed to evaluate the relationship between life quality and use of complementary and alternative medicine (CAM) in patients with diabetes mellitus. METHODS: The Audit of Diabetes-Dependent Quality of Life (ADDQOL-19) scale was applied to 453 diabetic patients. Socio-demographic characteristics of the patients and their CAM usage were recorded. RESULTS: The rate of CAM use among diabetic patients was 46.1%. The most preferred practices were herbal medicine, including black cumin (26...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29657429/isolation-and-identification-of-bacteria-causing-mastitis-in-small-ruminants-and-their-susceptibility-to-antibiotics-honey-essential-oils-and-plant-extracts
#8
Abeer Mostafa Abdalhamed, Gamil Sayed Gamil Zeedan, Hala Abdoula Ahmed Abou Zeina
Aim: The present work aims to isolate and identify bacteria that cause mastitis in small ruminants and evaluates the antibacterial activity of some antibiotics, honey, essential oils, and plant extracts. Materials and Methods: A total of 289 milk samples were collected from udder secretions of sheep (n=189) and goat (n=100) from El-Fayoum, Beni-Suef, and Giza governorates. Screening subclinical mastitis (SCM) was done using California Mastitis Test (CMT); identification of the isolates was achieved using Gram's staining, hemolytic pattern, colony morphology, and biochemical tests using Analytical Profile Index...
March 2018: Veterinary World
https://www.readbyqxmd.com/read/29656006/par-4-dependent-p53-up-regulation-plays-a-critical-role-in-thymoquinone-induced-cellular-senescence-in-human-malignant-glioma-cells
#9
Karthikeyan Subburayan, Faisal Thayyullathil, Siraj Pallichankandy, Anees Rahman, Sehamuddin Galadari
Thymoquinone (TQ), the predominant bioactive constituent present in black cumin (Nigella sativa), exerts tumor suppressive activity against a wide variety of cancer cells. Cellular senescence, characterized by stable and long term loss of proliferative capacity, acts as a potent tumor suppressive mechanism. Here, we provide evidence for the first time that TQ suppresses growth of glioma cells by potentially inducing the expression of prostate apoptosis response-4 (Par-4) tumor suppressor protein. In turn, TQ-induced Par-4 expression triggers cellular senescence, as evidenced by increasing cellular size, β-galactosidase staining, G1 phase arrest, and increased expression of senescence markers such as p53, p21, Rb, and decreased expression of lamin B1, cyclin E and cyclin depended kinase-2 (CDK-2)...
July 10, 2018: Cancer Letters
https://www.readbyqxmd.com/read/29648463/protective-effect-of-thymoquinone-the-main-component-of-nigella-sativa-against-diazinon-cardio-toxicity-in-rats
#10
Gholam Hassan Danaei, Bahram Memar, Ramin Ataee, Mohammad Karami
Several studies have shown that oxidative stress and cell damage can occur at very early stages of diazinon (DZN) exposure. The present study was designed to determine the beneficial effect of thymoquinone (Thy), the main component of Nigella sativa (black seed or black cumin), against DZN cardio-toxicity in rats. In the present experimental study, 48 male Wistar rats were randomly divided into six groups: control (corn oil gavages), DZN gavages (20 mg/kg/day), Thy gavages (10 mg/kg/day) and Thy + DVN gavages (2...
April 12, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29616559/urinary-bladder-stone-passing-using-a-persian-herbal-recipe
#11
Ayda Hosseinkhani, Fatemeh Tabatabaei, Maryam Mosaffa-Jahromi, Mehdi Pasalar
OBJECTIVE: The intrauterine device (IUD) is a popular contraceptive instrument with reported complications. IUD migration to the urinary bladder, a rare genitourinary tricky situation, may cause stone formation and result in urinary system sequels such as a stone formation and a recurrent infection. CASE REPORT: This is a case report of IUD migration to the urinary bladder, mineralization, and subsequent complications. We report the case of a 35-year-old woman with a copper IUD nidus stone in her urinary bladder...
January 2018: Journal of evidence-based integrative medicine
https://www.readbyqxmd.com/read/29606771/effect-of-black-cumin-oil-on-the-oxidative-stability-and-sensory-characteristics-of-mayonnaise
#12
Necla Ozdemir, Meryem Nur Kantekin-Erdogan, Tuba Tat, Aziz Tekin
Mayonnaise is one of the most commonly used sauces all over the world but it is vulnerable to oxidation because of its high oil content. Using natural antioxidants instead of synthetic ones is a popular and promising topic in the food industry. The aim of this study was to increase the oxidative stability of mayonnaise using cold-pressed black cumin oil (BCO), which has high antioxidant activity due to its phenolic content. Four different mayonnaise formulations were used: Mayo-Control, Mayo-5% BCO, Mayo-10% BCO, and Mayo-20% BCO, which refer to a 0 (control), 5, 10, and 20% BCO replacement of total sunflower oil content, respectively...
April 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29606758/some-microbiological-physicochemical-and-ripening-properties-of-erzincan-tulum-cheese-produced-with-added-black-cumin-nigella-sativa-l
#13
Yusuf Çakır, Songül Çakmakçı
The effects of black cumin (BC) at 0, 1 or 2% in Erzincan Tulum cheese (Tulum cheese) on its microbiological, chemical and proteolysis properties during ripening were investigated. The addition of BC caused an increase in the dry matter, protein, ash, total nitrogen (TN), water-soluble nitrogen (WSN) (% of TN) (ripening index), 5% phosphotungstic acid soluble nitrogen (PTA-SN) (% of TN), and 12% trichloroacetic acid soluble nitrogen (TCA-SN) (% of TN) concentrations compared to BC-free (control) cheese. Additionally, the addition of BC caused a decrease in coliforms, yeasts & moulds, fat-in-dry matter (FDM), pH, and acidity...
April 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29604618/an-open-prospective-pilot-study-of-a-herbal-combination-relief-as-a-supportive-dietetic-measure-during-alcohol-withdrawal
#14
Kenza Mansoor, Fadi Qadan, Andreas Hinum, Caroline Schneider, Klaus Hechenbichler, Mathias Schmidt, Georg Linsinger, Khalid Matalka
OBJECTIVE: A herbal combination (saffron extract, passion flower herb extract, cocoa seed extract, radish extract and black cumin extract) called "Relief" was designed as a supportive therapy of alcohol withdrawal syndrome (AWS). This combination was based on the scientific evidence of each constituent effect on AWS-like symptoms. In addition, our preclinical studies have shown the effectiveness of Relief on AWS detoxification. The rationale of the study was to document whether the oral intake of the designed content of Relief could have a positive effect on the course of alcohol detoxification by reducing some of the AWS in hospitalized patients...
March 27, 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29587770/powdered-black-cumin-seeds-strongly-improves-serum-lipids-atherogenic-index-of-plasma-and-modulates-anthropometric-features-in-patients-with-hashimoto-s-thyroiditis
#15
Mahdieh Abbasalizad Farhangi, Parvin Dehghan, Siroos Tajmiri
BACKGROUND: Hashimoto's thyroiditis is associated with serious alterations in serum lipids and glucose homeostasis. The aims of the current study were to evaluate the effect of powdered Nigella sativa on serum lipids, glucose homeostasis and anthropometric variables in patients with Hashimoto's thyroiditis. METHODS: Forty patients with Hashimoto's thyroiditis, aged between 22 and 50 years old, participated in the trial and were randomly allocated into two groups of intervention and control receiving powdered Nigella sativa or placebo daily for 8 weeks...
March 27, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29518971/dietary-plants-for-the-prevention-and-management-of-kidney-stones-preclinical-and-clinical-evidence-and-molecular-mechanisms
#16
REVIEW
Mina Cheraghi Nirumand, Marziyeh Hajialyani, Roja Rahimi, Mohammad Hosein Farzaei, Stéphane Zingue, Seyed Mohammad Nabavi, Anupam Bishayee
Kidney stones are one of the oldest known and common diseases in the urinary tract system. Various human studies have suggested that diets with a higher intake of vegetables and fruits play a role in the prevention of kidney stones. In this review, we have provided an overview of these dietary plants, their main chemical constituents, and their possible mechanisms of action. Camellia sinensis (green tea), Rubus idaeus (raspberry), Rubia cordifolia (common madder), Petroselinum crispum (parsley), Punica granatum (pomegranate), Pistacia lentiscus (mastic), Solanum xanthocarpum (yellow-fruit nightshade), Urtica dioica (stinging nettle), Dolichos biflorus ( horse gram ), Ammi visnaga (khella), Nigella sativa (black-cumin), Hibiscus sabdariffa (roselle), and Origanum vulgare (oregano) have received considerable interest based on scientific evidence...
March 7, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29493013/carcass-characteristics-chemical-and-fatty-acid-composition-and-oxidative-stability-of-meat-from-broiler-chickens-fed-black-cumin-nigella-sativa-seeds
#17
P Kumar, A K Patra, G P Mandal, B C Debnath
A study was conducted to investigate the dietary supplementation of black cumin seeds (BCS) on carcass characteristics, chemical and fatty acid (FA) composition and antioxidant properties of thigh and breast meat of broiler chickens at 42 days of age. Three hundred sixty 1-day-old broiler chickens were allocated to five dietary treatment groups (each group containing eight replicate pens with each pen containing nine broiler chickens): basal diet (control; CON), CON + 0.05 g/kg of bacitracin methylene disalicylate (AB), CON + 5 g/kg of BCS (low dose of BCS), CON + 10 g/kg of BCS (medium dose of BCS) and CON + 20 g/kg of BCS (high dose of BCS)...
June 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29455727/enhancement-of-gut-permeation-of-amoxicillin-with-nigella-sativa-seed-extract-and-its-phytochemical-screening
#18
Babar Ali, Mohammad Ali, Saima Amin, Showkat R Mir
The seeds of Nigella sativa Linn. (Ranunculaceae), commonly known as Black cumin, are predominantly used as carminative, antispasmodic, and stimulant. The main objective of the present study was to evaluate the effect of N. sativa seed extract on the permeation of co-infused amoxicillin across the gut wall. The methanolic extract of N. sativa improved intestinal permeability of amoxicillin in in-vitro experiments in a dose-dependent manner. Two new glycosides, decanyl nigelloic acid diglucoside [n-decanyl-3-aldehydic-4-methoxy-5-hydroxy benzoate-5-β-D-glucofuranosyl (2→1)-β-D-glucopyranosyl-(2→1)-β-D-glucopyranoside]] and nigelabdienoyl triglucoside [homo-labd-5, 9(11)-dien-16-onyl-β-D-glucopyranosyl (2→1)-β-D-glucopyranosyl (2→1)-β-D-glucopyranoside], along with seven known fatty acid glycerides/esters, were isolated from the gut permeation enhancing extract...
February 2018: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/29433684/short-and-long-term-modulation-of-tissue-minerals-concentrations-following-oral-administration-of-black-cumin-nigella-sativa-l-seed-oil-to-laboratory-rats
#19
Irum Basheer, Irfan Zia Qureshi
BACKGROUND: Nigella sativa, or commonly called black cumin is a small herb of family Ranunculaceae is a well-known medicinal plant but its effects on tissue mineral concentrations of animal bodies is unknown. PURPOSE: To study the effect of oral administration of fixed oil of black cumin seeds on tissues mineral content using laboratory rats as experimental model. STUDY DESIGN: Experimental animals were exposed to two oral doses of seed oil (60 and 120 ml kg-1 body weight)...
January 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29403626/a-review-of-effective-herbal-medicines-in-controlling-menopausal-symptoms
#20
REVIEW
Rahele Kargozar, Hoda Azizi, Roshanak Salari
Background: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. Objective: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms...
November 2017: Electronic Physician
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