Read by QxMD icon Read


Paul E Wischmeyer, Michelle M McMoon, Nathan H Waldron, Elizabeth J Dye
BACKGROUND: Enteral feeding via feeding tube (FT) provides essential nutrition support to critically ill patients or those who cannot intake adequate nutrition via the oral route. Unfortunately, 1%-2% of FTs placed blindly at bedside enter the airway undetected (as confirmed by x-ray), where they could result in adverse events. Misplaced FTs can cause complications including pneumothorax, vocal cord injury, bronchopleural fistula, pneumonia, and death. X-ray is typically performed to confirm FT placement before feeding, but may delay nutrition intake, may not universally identify misplacement, and adds cost and radiation exposure...
June 20, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Miguel-Ángel Gómez, Simcha Avugos, Miguel-Ángel Oñoro, Alberto Lorenzo, Michael Bar-Eli
It has been previously observed that basketball free-throw (FT) shooting efficiency decreases towards the end of the game. The aim of the current study was to explore possible determinants for this distinctive pattern during close games (point differential of equal or under 2 points during the final minute of the game). A sample of shots attempted by 92 players in the Spanish professional basketball league (ACB) was collected. Several personal (age, experience, playing position and career FT percentage) and contextual (team ability, competition stage, game location, seconds remaining and score differential) variables were considered for the analysis of the data...
June 2018: Journal of Human Kinetics
Jee-Eun Jang, Hwang-Phill Kim, Sae-Won Han, Hoon Jang, Si-Hyun Lee, Sang-Hyun Song, Duhee Bang, Tae-You Kim
Purpose: This study was designed to identify novel fusion transcripts (FTs) and their functional significance in colorectal cancer lines. Materials and Methods: We performed paired-end RNA sequencing of 28 colorectal cancer (CRC) cell lines. FT candidates were identified using TopHat-fusion, ChimeraScan, and FusionMap tools and further experimental validation was conducted through reverse transcription-polymerase chain reaction and Sanger sequencing. FT was depleted in human CRC line and the effects on cell proliferation, cell migration, and cell invasion were analyzed...
June 14, 2018: Cancer Research and Treatment: Official Journal of Korean Cancer Association
Katerina Soulantica, Justine Harmel, Laurent Peres, Marta Estrader, Adrien Berliet, Sylvie Maury, Antoine Fécant, Bruno Chaudret, Philippe Serp
The possibility to control the structural characteristics of the active phase of supported catalysts offers the opportunity to improve catalyst performance, especially in structure sensitive catalytic reactions. In parallel, heat management is of critical importance for the catalytic performance in highly endo- or exothermic reactions. The Fisher-Tropsch synthesis (FTS) is a structure sensitive exothermic reaction, which enables catalytic transformation of syngas to high quality liquid fuels. We have elaborated monolithic cobalt based heterogeneous catalysts through a wet chemistry approach that allows control over nanocrystal shape and crystallographic phase, while at the same time enables heat management...
June 12, 2018: Angewandte Chemie
Leslie A Parker, Jessica H Withers, Elizabeth Talaga
BACKGROUND: Oral-nasogastric feeding tubes (FTs) are often malpositioned, placing infants at risk for complications. Confusion exists regarding the accuracy of methods to determine FT insertion length and verify gastric FT placement, and it is unknown whether evidence-based methods are used by neonatal nurses. PURPOSE: To compare individual and unit-based neonatal nursing practices regarding methods used to determine FT insertion length and verify gastric FT placement...
June 8, 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Jingjing Sun, Lingyi Sun, Jianchun Li, Jieni Xu, Zhuoya Wan, Zubin Ouyang, Lei Liang, Song Li, Dexing Zeng
Multifunctional nanoplatforms offering simultaneous imaging and therapeutic functions have been recognized as a highly promising strategy for personalized nanomedicine. In this work, we synthesized a farnesylthiosalicylate (FTS, a nontoxic Ras antagonist) based triblock copolymer POEG-b-PVBA-b-PFTS (POVF) composed of a poly(oligo(ethylene glycol) methacrylate) (POEG) hydrophilic block, a poly(FTS) hydrophobic block, and a poly(4-vinylbenzyl azide) (PVBA) middle block. The POVF polymer itself was active in inhibiting the tumor growth in vitro and in vivo...
June 6, 2018: Acta Biomaterialia
Jiwon Yu, Jonghyeok Shin, Myoungseo Park, Emine Seydametova, Sang-Min Jung, Jin-Ho Seo, Dae-Hyuk Kweon
Fucosyllactoses (FLs), present in human breast milk, have been reported to benefit human health immensely. Especially, 3-fucosyllactose (3-FL) has numerous benefits associated with a healthy gut ecosystem. Metabolic engineering of microorganisms is thought to be currently the only option to provide an economically feasible route for large-scale production of 3-FL. However, engineering principles for α-1,3-fucosyltransferases (1,3-FTs) are not well-known, resulting in the lower productivity of 3-FL than that of 2'-fucosyllactose (2'-FL), although both 2'-FL and 3-FL follow a common pathway to produce GDP-L-fucose...
June 2, 2018: Metabolic Engineering
Jill Wenderott, Peter F Green
The role of self-assembled monolayers (SAMs), trichloro (1H, 1H, 2H, 2H-perfluorooctyl) (FTS) and octadecyltrichlorosilane (OTS), deposited on indium tin oxide (ITO) substrates, on electronic properties of the poly(3-hexylthiophene) (P3HT)/SAM/ITO system is reported. SAMs, well known for modifying the surface energies of materials, are also known to modify the work functions (WFs) of semiconductors. Unsurprisingly, differences between the band bending behaviors of P3HT/ITO, P3HT/OTS/ITO, and P3HT/FTS/ITO systems were observed, since the SAMs modify the WF of ITO...
May 30, 2018: ACS Applied Materials & Interfaces
Nathaniel Dziuba, Joanne Hardy, Paul A Lindahl
Blood contains a poorly characterized pool of labile iron called non-transferrin-bound iron (NTBI). In patients with iron-overload diseases such as hemochromatosis, NTBI accumulates in the liver, heart, and other organs. This material is probably nonproteinaceous and low molecular mass (LMM). However, the number, concentration, mass, and chemical composition of NTBI species remain unknown despite decades of effort. Here, solutions of plasma from humans, pigs, horses, and mice were passed through a 10 kDa cutoff membrane, affording flow-through solutions (FTSs) containing ∼1 μM iron...
May 29, 2018: Metallomics: Integrated Biometal Science
Gonzalo de la Iglesia, André Walter, Fernando de la Iglesia, Heinz Winsauer, Andreu Puigdollers
INTRODUCTION: The force applied to the teeth by fixed orthopaedic expanders has previously been studied, but not the force applied to the orthodontic mini-implant (OMI) used to expand the maxilla with Hyrax hybrid expanders (HHE). OBJECTIVE: The aim of this article was to evaluate the clinical safety of the components (OMI, abutment and double wire arms) of three different force-transmitting systems (FTS) for conducting orthopaedic maxillary expansion: Jeil Medical & Tiger Dental™, Microdent™ and Ortholox™...
January 2018: Dental Press Journal of Orthodontics
Balmatee Bidassie, William Gunnar, Leigh Starr, George Van Buskirk, Lisa Warner, Clifford Anckaitis, Angela Howard
Purpose During years 2014-2016, Veterans Health Administration National Surgery Office conducted a surgical flow improvement initiative (SFII) to assist low-performing surgery programs to improve their operating room efficiency (ORE). The initiative was co-sponsored by VHA National Surgery Office and VHA Office of Systems Redesign and Improvement. The paper aims to discuss this issue. Design/methodology/approach An SFII algorithm, based on first-time-start (FTS), cancellation rate (CR), lag time (LT) and OR utilization, assigned an ORE performance Level (1-low to 4-high) to each VA Medical Center (VAMC)...
May 14, 2018: International Journal of Health Care Quality Assurance
Zhichao Huang, Lu Yi, Zhaohui Zhong, Liang Zhu, Hongqing Zhao, Yijian Li, Yeqi Nian, Peng Xu, Yinhuai Wang
Fast-track surgery (FTS), which includes a series of evidence-based adjustments, is expected to reduce complications, relieve surgical stress reaction, accelerate recovery, and shorten hospitalization, as well as improve safety. The aim of this study was to critically evaluate the safety and effectiveness of FTS in Chinese prostate cancer (Pca) patients who underwent robot-assisted laparoscopic prostatectomy (RALP). A retrospective analysis was performed on 73 consecutive Chinese Pca patients who underwent RALP and who were divided into two groups: conventional surgery (CS) and FTS...
May 22, 2018: Scientific Reports
Ragnhild I Vestrum, Kari J K Attramadal, Per Winge, Keshuai Li, Yngvar Olsen, Atle M Bones, Olav Vadstein, Ingrid Bakke
We have previously shown that K-selection and microbial stability in the rearing water increases survival and growth of Atlantic cod ( Gadus morhua ) larvae, and that recirculating aquaculture systems (RAS) are compatible with this. Here, we have assessed how water treatment influenced the larval microbiota and host responses at the gene expression level. Cod larvae were reared with two different rearing water systems: a RAS and a flow-through system (FTS). The water microbiota was examined using a 16S rDNA PCR/DGGE strategy...
2018: Frontiers in Microbiology
Andrew T Strong, Hana Fayazzadeh, Gautam Sharma, Kevin El-Hayek, Matthew Kroh, John Rodriguez
BACKGROUND: Revisional bariatric surgery (RBS) is associated with higher complication rates compared with primary bariatric surgery. Feeding tubes (FTs), including gastrostomy and jejunostomy tubes placed during RBS, may serve as a safety net to provide nutrition when oral intake is contraindicated or limited; however, FTs in this setting have not been well investigated. OBJECTIVES: This study aims to determine complications, use, and duration of FTs placed during RBS...
March 9, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Yi-Chun Lin, Siobhan Mullan, David C J Main
Lameness is one of the most serious economic and welfare issues in the dairy industry. Early detection of lameness can be difficult, but provision of early treatment is crucial. Previous studies have used infrared thermography to show that increased foot temperature (FT) is associated with lameness and foot lesions. However, poor accuracy has limited the management application potential. This study analysed ambient-temperature (AT)-adjusted foot-surface temperatures and temperature differences between the hind feet of individual cows to enhance lameness detection...
April 29, 2018: Veterinary Medicine and Science
Meriç Özcan, Behzad Sardari
In this study, experimental demonstration of a static Fourier transform spectrometer (static-FTS), based on division of the spectrum into multiple narrowband signals, is presented. The bandpass sampling technique used in this novel spectrometer solves the Nyquist sampling rate limitations and enables recording of wideband spectrum in high resolution. The proposed spectrometer not only has the potential of operating in a wide spectral range, but also has a resolution potential better than 2 cm-1 .
January 1, 2018: Applied Spectroscopy
Monique Ameyo Dorkenoo, Rachel Bronzan, Degninou Yehadji, Mawèke Tchalim, Kossi Yakpa, Santrao Etassoli, Poukpessi Adjeloh, Issaka Maman, Yao Sodahlon
BACKGROUND: Togo is a country previously endemic for lymphatic filariasis (LF). In 2010, following nine years of mass drug administration (MDA) for LF, the country established a post-treatment surveillance (PTS) system. We present here the results of these PTS activities, carried out from 2010 to 2015, as well as the findings of follow-up investigations in 2016 to confirm the absence of infection in previously infected individuals. METHODS: The routine surveillance established in 2010 consisted of a network of 47 laboratories, which searched for Wuchereria bancrofti microfilaria on nocturnal blood smears collected for malaria diagnosis and an additional network of 20 peripheral health facilities, which collected dried blood spots and tested them for Og4C3 antigen...
April 16, 2018: Parasites & Vectors
Nandini Mondal, Brad Dykstra, Jungmin Lee, David J Ashline, Vernon N Reinhold, Derrick J Rossi, Robert Sackstein
In humans, six α(1,3)-fucosyltransferases (α(1,3)-FTs: FT3/FT4/FT5/FT6/FT7/FT9) reportedly fucosylate terminal lactosaminyl glycans yielding Lewis-X (LeX ; CD15) and/or sialyl Lewis-X (sLeX ; CD15s), structures that play key functions in cell migration, development, and immunity. Prior studies analyzing α(1,3)-FT specificities utilized either purified and/or recombinant enzymes to modify synthetic substrates under nonphysiological reaction conditions or molecular biology approaches wherein α(1,3)-FTs were expressed in mammalian cell lines, notably excluding investigations using primary human cells...
May 11, 2018: Journal of Biological Chemistry
Nienke H van Dokkum, Marlou L A de Kroon, Arend F Bos, Sijmen A Reijneveld, Jorien M Kerstjens
BACKGROUND: Little is known on the motor development of moderately preterm born (MPT) children, in comparison with early preterm born (EPT) children and fullterm born (FT), for children with normal motor outcomes at school entry. AIMS: To compare attainment rates of gross motor milestones reached between ages 1-24 months for MPT, EPT, and FT children, all with normal development upon school entry. STUDY DESIGN: Prospective cohort study. SUBJECTS: We included 1247 preterm (PT) children (gestational age [GA] 24...
April 2018: Early Human Development
Ya Wang, Tingting Chen, Zihao Yuan, Yajie Zhang, Baofeng Zhang, Liandong Zhao, Ling Chen
Statins by reducing farnesyl-pyrophosphate or farnesyl transferase inhibitors have been demonstrated to enhance spatial memory and long-term potentiation (LTP). The objective of this study was to investigate effects of the synthetic Ras inhibitor S-trans, trans-farnesylthiosalicylic acid (FTS) on spatial cognitive function in adult mice, synaptic plasticity in hippocampal CA1 regions, and NMDA receptor (NMDAr) activity of pyramidal cells. Here, we show that administering FTS (5 mg/kg, i.p.) enhanced spatial cognitive performance, as assessed via Morris water maze and Y-maze tests...
March 22, 2018: Neuropharmacology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"