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Meriç Özcan, Behzad Sardari
In this study, experimental demonstration of a static Fourier transform spectrometer (static-FTS), based on division of the spectrum into multiple narrowband signals, is presented. The bandpass sampling technique used in this novel spectrometer solves the Nyquist sampling rate limitations and enables recording of wideband spectrum in high resolution. The proposed spectrometer not only has the potential of operating in a wide spectral range, but also has a resolution potential better than 2 cm-1 .
January 1, 2018: Applied Spectroscopy
Monique Ameyo Dorkenoo, Rachel Bronzan, Degninou Yehadji, Mawèke Tchalim, Kossi Yakpa, Santrao Etassoli, Poukpessi Adjeloh, Issaka Maman, Yao Sodahlon
BACKGROUND: Togo is a country previously endemic for lymphatic filariasis (LF). In 2010, following nine years of mass drug administration (MDA) for LF, the country established a post-treatment surveillance (PTS) system. We present here the results of these PTS activities, carried out from 2010 to 2015, as well as the findings of follow-up investigations in 2016 to confirm the absence of infection in previously infected individuals. METHODS: The routine surveillance established in 2010 consisted of a network of 47 laboratories, which searched for Wuchereria bancrofti microfilaria on nocturnal blood smears collected for malaria diagnosis and an additional network of 20 peripheral health facilities, which collected dried blood spots and tested them for Og4C3 antigen...
April 16, 2018: Parasites & Vectors
Nandini Mondal, Brad Dykstra, Jungmin Lee, David Ashline, Vernon N Reinhold, Derrick J Rossi, Robert Sackstein
In humans, six α(1,3)-fucosyltransferases (α(1,3)-FTs: FT3/FT4/FT5/FT6/FT7/FT9) reportedly fucosylate terminal lactosaminyl glycans yielding Lewis X (LeX ; CD15) and/or sialyl Lewis X (sLeX ; CD15s), structures that play key functions in cell migration, development, and immunity. Prior studies analyzing α(1,3)-FT-specificities utilized either purified and/or recombinant enzymes to modify synthetic substrates under non-physiological reaction conditions or molecular biology approaches wherein α(1,3)-FTs were expressed in mammalian cell lines, notably excluding investigations using primary human cells...
March 28, 2018: Journal of Biological Chemistry
Nienke H van Dokkum, Marlou L A de Kroon, Arend F Bos, Sijmen A Reijneveld, Jorien M Kerstjens
BACKGROUND: Little is known on the motor development of moderately preterm born (MPT) children, in comparison with early preterm born (EPT) children and fullterm born (FT), for children with normal motor outcomes at school entry. AIMS: To compare attainment rates of gross motor milestones reached between ages 1-24 months for MPT, EPT, and FT children, all with normal development upon school entry. STUDY DESIGN: Prospective cohort study. SUBJECTS: We included 1247 preterm (PT) children (gestational age [GA] 24...
March 23, 2018: Early Human Development
Ya Wang, Tingting Chen, Zihao Yuan, Yajie Zhang, Baofeng Zhang, Liandong Zhao, Ling Chen
Statins by reducing farnesyl-pyrophosphate or farnesyl transferase inhibitors have been demonstrated to enhance spatial memory and long-term potentiation (LTP). The objective of this study was to investigate effects of the synthetic Ras inhibitor S-trans, trans-farnesylthiosalicylic acid (FTS) on spatial cognitive function in adult mice, synaptic plasticity in hippocampal CA1 regions, and NMDA receptor (NMDAr) activity of pyramidal cells. Here, we show that administering FTS (5 mg/kg, i.p.) enhanced spatial cognitive performance, as assessed via Morris water maze and Y-maze tests...
March 22, 2018: Neuropharmacology
Pedro Teixeira Castro, Ana Paula Pinho Matos, Osvaldo Luiz Aranda, Edson Marchiori, Haimon Diniz Lopes Alves, Alessandra Silveira Machado, Ricardo Tadeu Lopes, Heron Werner, Edward Araujo Júnior
OBJECTIVE: The aim of this study was to provide a three-dimensional (3D) microscopic reconstruction of morphological modifications of the fallopian tube (FT) following surgical sterilization (including tuboperitoneal fistula) and ectopic pregnancy (EP) using confocal microtomography (micro-CT). METHODS: Six specimens of FT from elective and emergency surgeries were selected: three remnants of the FT (RFT) from surgical sterilization, including one presenting tuboperitoneal fistula, and three FTs with EP...
March 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
Yaron Caspi, Cees Dekker
Cell division in most prokaryotes is mediated by the well-studied fts genes, with FtsZ as the principal player. In many archaeal species, however, division is orchestrated differently. The Crenarchaeota phylum of archaea features the action of the three proteins, CdvABC. This Cdv system is a unique and less-well-studied division mechanism that merits closer inspection. In vivo , the three Cdv proteins form a composite band that contracts concomitantly with the septum formation. Of the three Cdv proteins, CdvA is the first to be recruited to the division site, while CdvB and CdvC are thought to participate in the active part of the Cdv division machinery...
2018: Frontiers in Microbiology
Yongrui Liu
Objective : To investigate the clinical effect of fast track surgery (FTS) in perioperative nursing of colorectal cancer surgery. Background : In recent years, many complicated surgery began to develop in the direction of low invasion and short hospital time, which provides an unprecedented opportunity for the development of fast track surgery (FTS). Methods : According to different nursing measures, 156 cases of colorectal cancer patients treated in our hospital were divided into FTS nursing group (86 cases) and traditional nursing group (70 cases)...
December 2017: Saudi Journal of Biological Sciences
Fiammetta Monacelli, Alessio Signori, Matteo Prefumo, Chiara Giannotti, Alessio Nencioni, Emanuele Romairone, Stefano Scabini, Patrizio Odetti
Background/Aims: Postoperative delirium (POD) is more frequent in elderly patients undergoing major cancer surgery. The interplay between individual clinical vulnerability and a series of perioperative factors seems to play a relevant role. Surgery is the first-line treatment option for cancer, and fast-track surgery (FTS) has been documented to decrease postoperative complications. The study sought to assess, after comprehensive geriatric assessment (CGA) and frailty stratification (Rockwood 40 items index), which perioperative parameters were predictive of POD development in elderly patients undergoing FTS for colorectal cancer...
January 2018: Dementia and Geriatric Cognitive Disorders Extra
Martijn Wehrens, Dmitry Ershov, Rutger Rozendaal, Noreen Walker, Daniel Schultz, Roy Kishony, Petra Anne Levin, Sander J Tans
Our understanding of bacterial cell size control is based mainly on stress-free growth conditions in the laboratory [1-10]. In the real world, however, bacteria are routinely faced with stresses that produce long filamentous cell morphologies [11-28]. Escherichia coli is observed to filament in response to DNA damage [22-25], antibiotic treatment [11-14, 28], host immune systems [15, 16], temperature [17], starvation [20], and more [18, 19, 21], conditions which are relevant to clinical settings and food preservation [26]...
February 22, 2018: Current Biology: CB
James R Lyons, Ehsan Gharib-Nezhad, Thomas R Ayres
Measurements by the Genesis mission have shown that solar wind oxygen is depleted in the rare isotopes,17 O and18 O, by approximately 80 and 100‰, respectively, relative to Earth's oceans, with inferred photospheric values of about -60‰ for both isotopes. Direct astronomical measurements of CO absorption lines in the solar photosphere have previously yielded a wide range of O isotope ratios. Here, we reanalyze the line strengths for high-temperature rovibrational transitions in photospheric CO from ATMOS FTS data, and obtain an18 O depletion of δ18 O = -50 ± 11‰ (1σ)...
March 2, 2018: Nature Communications
Feng Jiao, Xiulian Pan, Ke Gong, Yuxiang Chen, Gen Li, Xinhe Bao
Syngas conversion via Fischer-Tropsch synthesis (FTS) is characterized by a wide distribution of hydrocarbon products ranging from one to a few ten carbon atoms. We report here that selectivity can be effectively steered toward ethylene employing the oxide-zeolite (OX-ZEO) catalyst concept with ZnCrOx-mordenite (MOR). The selectivity of ethylene alone reaches as high as 73% at 26% CO conversion, in stark contrast to a maximum 30% predicted for C₂ hydrocarbons by the Anderson-Schultz-Flory (ASF) model in FTS...
March 2, 2018: Angewandte Chemie
Jan P Falkenhagen, Lise Maisonneuve, Pasi P Paalanen, Nathalie Coste, Nicolas Malicki, Bert M Weckhuysen
Co-Fe-Mn/γ-Al2 O3 Fischer-Tropsch synthesis (FTS) catalysts were synthesized, characterized and tested for CO hydrogenation, mimicking end-of-life-tire (ELT)-derived syngas. It was found that an increase of C2 -C4 olefin selectivities to 49 % could be reached for 5 wt % Co, 5 wt % Fe, 2.5 wt % Mn/γ-Al2 O3 with Na at ambient pressure. Furthermore, by using a 5 wt % Co, 5 wt % Fe, 2.5 wt % Mn, 1.2 wt % Na, 0.03 wt % S/γ-Al2 O3 catalyst the selectivity towards the fractions of C5+ and CH4 could be reduced, whereas the selectivity towards the fraction of C4 olefins could be improved to 12...
March 1, 2018: Chemistry: a European Journal
Shangyuan Jiang, Rong Z Gan
The incudostapedial joint (ISJ) is a synovial joint connecting the incus and stapes in the middle ear. Mechanical properties of the ISJ directly affect sound transmission from the tympanic membrane to the cochlea. However, how ISJ properties change with frequency has not been investigated. In this paper, we report the dynamic properties of the human ISJ measured in eight samples using a dynamic mechanical analyzer (DMA) for frequencies from 1 to 80 Hz at three temperatures of 5, 25 and 37 °C. The frequency-temperature superposition (FTS) principle was used to extrapolate the results to 8 kHz...
February 22, 2018: Medical Engineering & Physics
Pavla Stojkova, Petra Spidlova, Juraj Lenco, Helena Rehulkova, Lucie Kratka, Jiri Stulik
The nucleoid-associated HU proteins are small abundant DNA-binding proteins in bacterial cell which play an important role in the initiation of DNA replication, cell division, SOS response, control of gene expression and recombination. HU proteins bind to double stranded DNA non-specifically, but they exhibit high affinity to abnormal DNA structures as four-way junctions, gaps or nicks, which are generated during DNA damage. In many pathogens HU proteins regulate expression of genes involved in metabolism and virulence...
February 23, 2018: Virulence
Cynthia A Stifter, Kameron J Moding
OBJECTIVES: Greater weight gain in infancy is a risk factor for childhood obesity. The present study examined the interaction between infant temperament and parent use of food to soothe infant distress (FTS) as predictors of weight gain across the first 2 years of life. SUBJECTS/METHODS: A total of 160 mother-infant dyads were recruited into a longitudinal study. Infant temperament was assessed by parents through a questionnaire (surgency, negativity) and by observer ratings (surgency, irritability) during a laboratory visit when infants were 6 months old...
January 30, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Mario C M M Souza, Andrew Grieco, Newton C Frateschi, Yeshaiahu Fainman
Miniaturized integrated spectrometers will have unprecedented impact on applications ranging from unmanned aerial vehicles to mobile phones, and silicon photonics promises to deliver compact, cost-effective devices. Mirroring its ubiquitous free-space counterpart, a silicon photonics-based Fourier transform spectrometer (Si-FTS) can bring broadband operation and fine resolution to the chip scale. Here we present the modeling and experimental demonstration of a thermally tuned Si-FTS accounting for dispersion, thermo-optic non-linearity, and thermal expansion...
February 14, 2018: Nature Communications
Mohamed Abbas, Juan Zhang, Ke Lin, Jiangang Chen
In this study, Fe3O4 nanocubes (NCs) decorated on RGO nanosheets (NSs) structures were successfully synthesized through an innovative and environmentally-friendly rapid sonochemical method. More importantly, iron(II) sulfate heptahydrate and GO were employed as precursors and water as reaction medium, meanwhile, NaOH within the generated free radicals from the high intensity ultrasound were sufficient as reducing and base agent in our clean synthesis. Moreover, the hydrothermal method as a conventional approach was employed to synthesize the same catalysts for the comparison with the ultrasonocation technique...
April 2018: Ultrasonics Sonochemistry
Maximilian K G Ehrhardt, Suzanne L Warring, Monica L Gerth
Identifying the ligands sensed by chemoreceptors remains challenging, in part because current screening methods are low-throughput, costly, and/or time-consuming. In contrast, fluorescence thermal shift (FTS) assays provide a fast and inexpensive approach to chemoreceptor-ligand screening. In FTS assays, the temperature at which a protein denatures is measured by monitoring the fluorescence of a dye with affinity for hydrophobic regions of the protein, which are exposed as the protein unfolds. A detectable increase (or "shift") in the melting temperature (T m ) of the protein in the presence of a potential ligand indicates binding...
2018: Methods in Molecular Biology
Yoram A Weil, Feras Qawasmi, Meir Liebergall, Rami Mosheiff, Amal Khoury
BACKGROUND: Femoral neck fractures (FNF) are becoming increasingly common as population ages. Nondisplaced fractures are commonly treated by cancellous, parallel placed, partially threaded cannulated screws (PTS). This allows controlled fracture impaction. However, sliding implants can lead to femoral neck shortening (FNS) that has been shown to be correlated with reduced quality of life and impaired gait pattern. Recently, in our institution we have changed the fixation of FNF to fully threaded screws (FTS) with or without an additional partially threaded screw in order to minimize this phenomenon...
February 9, 2018: Archives of Orthopaedic and Trauma Surgery
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