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https://www.readbyqxmd.com/read/29041194/highly-efficient-machining-of-non-circular-freeform-optics-using-fast-tool-servo-assisted-ultra-precision-turning
#1
Zexiao Li, Fengzhou Fang, Xiaodong Zhang, Xianlei Liu, Huimin Gao
Freeform optics has been regarded as the next generation of the optical components, especially those with non-circular apertures are playing an increasingly significant role in scanning field and specialized optical system. However, there still exist challenges to machine non-circular optical freeform surface. This paper is focused on highly efficiently generating freeform surfaces with optical surface quality by ultra-precision turning using a fast tool servo (FTS). A systematic strategy of machining smooth freeform surfaces with rectangular aperture is proposed in this paper...
October 16, 2017: Optics Express
https://www.readbyqxmd.com/read/29041118/broadband-fourier-transform-spectrometer-enabling-modal-subset-identification-in-fabry-p%C3%A3-rot-based-astrocombs
#2
Jake M Charsley, Richard A McCracken, Lauren Reid, Derryck T Reid
A multi-GHz frequency comb (astrocomb) is typically realized by filtering modes of a sub-GHz frequency comb (source comb) in a Fabry-Pérot etalon, which can lead to ambiguities in determining which subset of source comb modes has been filtered. Here we demonstrate a broadband Fourier-transform spectrometer (FTS) with a resolving power of R = 430,000 at 550 nm, and apply it to the identification of comb subsets from a filtered 1‑GHz supercontinuum. After apodization the FTS demonstrated an instrument line shape width of 1...
August 7, 2017: Optics Express
https://www.readbyqxmd.com/read/29032676/following-the-molecular-mechanism-of-decarbonylation-of-unsaturated-cyclic-ketones-using-bonding-evolution-theory-coupled-with-nci-analysis
#3
Ehsan Zahedi, Samaneh Shaabani, Abolfazl Shiroudi
The synergetic use of bonding evolution theory (BET) and non-covalent interaction (NCI) analysis allows to obtain new insight into the bond breaking/forming processes and electron redistribution along the reaction path to understand the molecular mechanism of a reaction and recognize regions of strong and weak electron pairing. This viewpoint has been considered for cheletropic extrusion of CO from unsaturated cyclic ketones cyclohepta-3,5-dien-1-one CHD, cyclopent-3-en-1-one CPE and bicyclo[2.2.1]hept-2-en-7-one BCH by using hybrid functional MPWB1K in conjugation with aug-cc-pVTZ basis set...
October 15, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29021972/evaluating-factors-for-prophylactic-feeding-tube-placement-in-gastroesophageal-cancer-patients-undergoing-chemoradiotherapy
#4
Vivek Verma, Pamela K Allen, Steven H Lin
PURPOSE: Though better studied in head/neck cancers, there are currently no studies on timing of feeding tube (FT) placement in patients with gastroesophageal cancer. This study sought to discern characteristics of patients who used versus did not use a prophylactic FT (pFT), and also analyzed factors associated with placement of FTs during chemoradiotherapy (CRT). METHODS/MATERIALS: From 1998 to 2013, 1,329 patients underwent neoadjuvant CRT, of which 323 received an FT...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28992213/repression-of-terminal-flower1-primarily-mediates-floral-induction-in-pear-pyrus-pyrifolia-nakai-concomitant-with-change-in-gene-expression-of-plant-hormone-related-genes-and-transcription-factors
#5
Songling Bai, Pham Anh Tuan, Takanori Saito, Akiko Ito, Benjamin Ewa Ubi, Yusuke Ban, Takaya Moriguchi
Floral induction is an important event in the annual growth cycle of perennial fruit trees. For pear, this event directly affects fruit production in the following year. The flower buds in many species are induced by FLOWERING LOCUS T (FT), whose effect is repressed by the meristem-expressed gene TERMINAL FLOWER1 (TFL1). In this study, we investigated the functions of pear FT and TFL1 genes during floral development. Expression of pear FTs (PpFT1a and PpFT2a) in reproductive meristems was not obviously induced prior to floral initiation, while expression of TFL1s (PpTFL1-1a and PpTFL1-2a) rapidly decreased...
September 7, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28959218/maternal-sensitivity-buffers-the-association-between-slc6a4-methylation-and-socio-emotional-stress-response-in-3-month-old-full-term-but-not-very-preterm-infants
#6
Livio Provenzi, Monica Fumagalli, Roberto Giorda, Francesco Morandi, Ida Sirgiovanni, Uberto Pozzoli, Fabio Mosca, Renato Borgatti, Rosario Montirosso
BACKGROUND: Very preterm (VPT) infants are hospitalized in Neonatal Intensive Care Units (NICUs) and are exposed to life-saving procedures eliciting pain-related stress. Recent research documented that pain-related stress might result in birth-to-discharge increased methylation of serotonin transporter gene (SLC6A4) in VPT infants, leading to poorer stress regulation at 3 months of age in VPT infants compared to their full-term (FT) counterparts. Maternal sensitivity is thought to support infants' stress response, but its role in moderating the effects of altered SLC6A4 methylation is unknown...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28949259/peripherally-inserted-central-catheters-dependency-of-radiation-exposure-from-puncture-site-and-level-of-training
#7
Martin Jonczyk, Bernhard Gebauer, Dirk Schnapauff, Roman Rotzinger, Bernd Hamm, Federico Collettini
Background Several interventional procedures show a dependency on fluoroscopy times (FT) and level of training. Furthermore, FT and dose area products (DAP) vary depending on access site and target vessel for chest port implantations, but not for other thoracic interventions such as percutaneous coronary interventions. Purpose To evaluate the influence of the combination of venous access site and level of training on FTs and DAPs during peripherally inserted central catheters (PICC) implantations in a large cohort of patients...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28939742/integrated-analysis-reveals-tubal-and-ovarian-originated-serous-ovarian-cancer-and-predicts-differential-therapeutic-responses
#8
Dapeng Hao, Jingjing Li, Shanshan Jia, Yuan Meng, Li Wang, Chao Zhang, Li-Jun Di
PURPOSE: The relative importance of fallopian tube (FT) compared to ovarian surface epithelium (OSE) in the genesis of serous type of ovarian cancer (SOC) is still unsettled. Here, we followed an integrated approach to study the tissue origin of SOC, as well as its association with clinical outcome and response to therapeutic drugs. EXPERIMENTAL DESIGN: A collection of transcriptome data of 80 FTs, 89 OSEs and 2,668 SOCs was systematically analyzed to determine the characteristic of FT-like and OSE-like tumors...
September 22, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28932707/neisseria-gonorrhoeae-challenge-increases-matrix-metalloproteinase-8-expression-in-fallopian-tube-explants
#9
Natalia E Juica, Paula I Rodas, Paula Solar, Paula Borda, Renato Vargas, Cristobal Muñoz, Rodolfo Paredes, Myron Christodoulides, Luis A Velasquez
Background:Neisseria gonorrhoeae (Ngo) is the etiological agent of gonorrhea, a sexually transmitted infection that initially infects the female lower genital tract. In untreated women, the bacteria can ascend to the upper genital reproductive tract and infect the fallopian tube (FTs), which is associated with salpingitis and can lead to impaired FT function and infertility. The extracellular matrix (ECM) plays an important role in cell migration and differentiation in the female genital tract, and some pathogens modify the ECM to establish successful infections...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28892505/frailty-is-associated-with-objectively-assessed-sedentary-behaviour-patterns-in-older-adults-evidence-from-the-toledo-study-for-healthy-aging-tsha
#10
Borja Del Pozo-Cruz, Asier Mañas, María Martín-García, Jorge Marín-Puyalto, Francisco J García-García, Leocadio Rodriguez-Mañas, Amelia Guadalupe-Grau, Ignacio Ara
OBJECTIVE: The aim of this study was to examine the association of sedentary behaviour patterns with frailty in older people. SETTING: Clinical setting. DESIGN: Cross-sectional, observational study. PARTICIPANTS AND MEASUREMENTS: A triaxial accelerometer was used in a subsample from the Toledo Study for Healthy Aging (519 participants, 67-97 years) to assess several sedentary behaviour patterns including sedentary time per day, the number and duration (min) of breaks in sedentary time per day, and the proportion of the day spent in sedentary bouts of 10 minutes or more...
2017: PloS One
https://www.readbyqxmd.com/read/28892473/a-multi-center-field-study-of-two-point-of-care-tests-for-circulating-wuchereria-bancrofti-antigenemia-in-africa
#11
MULTICENTER STUDY
Cédric B Chesnais, Naomi-Pitchouna Awaca-Uvon, Fatoma K Bolay, Michel Boussinesq, Peter U Fischer, Lincoln Gankpala, Aboulaye Meite, François Missamou, Sébastien D Pion, Gary J Weil
BACKGROUND: The Global Programme to Eliminate Lymphatic Filariasis uses point-of-care tests for circulating filarial antigenemia (CFA) to map endemic areas and for monitoring and evaluating the success of mass drug administration (MDA) programs. We compared the performance of the reference BinaxNOW Filariasis card test (ICT, introduced in 1997) with the Alere Filariasis Test Strip (FTS, introduced in 2013) in 5 endemic study sites in Africa. METHODOLOGY: The tests were compared prior to MDA in two study sites (Congo and Côte d'Ivoire) and in three sites that had received MDA (DRC and 2 sites in Liberia)...
September 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28873677/effect-of-the-phytate-and-hydrogen-peroxide-chemical-modifications-on-the-physicochemical-and-functional-properties-of-wheat-starch
#12
Fusheng Sun, Jiannan Liu, Xiyan Liu, Yuesheng Wang, Kexiu Li, Junli Chang, Guangxiao Yang, Guangyuan He
To investigate the characteristics of chemically modified wheat starch, such as oxidized (OWS), cross-linked (CLWS) and dual-modified wheat starches, cross-linked oxidized (COWS) and oxidized cross-linked (OCWS) wheat starches were obtained by 12% hydrogen peroxide (H2O2) and 2% sodium phytate treatments, respectively. After modifications of wheat starch by cross-linking and oxidization, it was determined that native wheat starch was effectively modified with respect to the structure and physicochemical characteristics, as detected by Fourier transform infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC), Rapid Visco Analyzer (RVA), scanning electron microscopy (SEM) and X-ray diffraction (XRD)...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28870159/obstetric-professionals-perceptions-of-non-invasive-prenatal-testing-for-down-syndrome-clinical-usefulness-compared-with-existing-tests-and-ethical-implications
#13
Olivia Miu Yung Ngan, Huso Yi, Samuel Yeung Shan Wong, Daljit Sahota, Shenaz Ahmed
BACKGROUND: While non-invasive prenatal testing (NIPT) for fetal aneuploidy is commercially available in many countries, little is known about how obstetric professionals in non-Western populations perceive the clinical usefulness of NIPT in comparison with existing first-trimester combined screening (FTS) for Down syndrome (DS) or invasive prenatal diagnosis (IPD), or perceptions of their ethical concerns arising from the use of NIPT. METHODS: A cross-sectional survey among 327 obstetric professionals (237 midwives, 90 obstetricians) in Hong Kong...
September 5, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28865209/impact-of-production-technology-on-morphological-lesions-in-the-gills-of-commercial-rainbow-trout-oncorhynchus-mykiss-walbaum-1792
#14
E Strzyżewska-Worotyńska, J Szarek, I Babińska, D Gulda
The most popular rainbow trout (Oncorhynchus mykiss, Walbaum 1792) production technologies include both an extensive method with the flow through system (FTS) and an intensive method with the recirculating aquaculture system (RAS). Their impact on the fish was evaluated with a morphological assessment of the gills, as these are organs susceptible to environmental changes. Trout of 350 - 500 g body mass were caught for trial in spring and autumn, with 36 fish originating from 3 fish farms with the FTS system and an equal number from 3 RAS fish farms (n = 6)...
March 1, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28855545/influence-of-oxalate-ligand-functionalization-on-co-zsm-5-activity-in-fischer-tropsch-synthesis-and-hydrodeoxygenation-of-oleic-acid-into-hydrocarbon-fuels
#15
Olumide Bolarinwa Ayodele
Achieving high degree of active metal dispersions at the highest possible metal loading and high reducibility of the metal remains a challenge in Fischer Tropsch synthesis (FTS) as well as in hydrogeoxygenation (HDO).This study therefore reports the influence of oxalic acid (OxA) functionalization on the metal dispersion, reducibility and activity of Co supported ZSM-5 catalyst in FTS and HDO of oleic acid into paraffin biofuel. The Brunauer-Emmett-Teller (BET) results showed that cobalt oxalate supported ZSM-5 catalyst (CoOx/ZSM-5) synthesized from the incorporation of freshly prepared cobalt oxalate complex into ZSM-5 displayed increase in surface area, pore volume and average pore size while the nonfunctionalized cobalt supported on ZSM-5 (Co/ZSM-5) catalyst showed reduction in those properties...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28854920/fibroma-of-tendon-sheath-around-large-joints-clinical-characteristics-and-literature-review
#16
Kayo Suzuki, Taketoshi Yasuda, Shun Suzawa, Kenta Watanabe, Masahiko Kanamori, Tomoatsu Kimura
BACKGROUND: Fibroma of tendon sheath (FTS) is a benign tumor arising from the synovium of the tendon sheath that occurs mostly around small joints such as the fingers, hands, and wrist. However, FTS rarely arises around a large joint (knee, shoulder, elbow, and ankle) with intra-articular or extra-articular involvement. The clinical characteristics of FTS arising around a large joint are unclear. An additional 3 cases of FTS arising around a large joint are presented. Furthermore, the published cases and the present cases are reviewed with respect to their clinical characteristics and imaging and histopathology findings...
August 30, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28808081/%C3%A2-eluxadoline-for-ibs-d
#17
(no author information available yet)
Irritable bowel syndrome (IBS) is a chronic relapsing gastrointestinal problem characterised by intestinal pain and associated alterations of defecation and/or bowel habit (constipation: IBS-C or diarrhoea: IBS-D).(1,2) Opioid receptors in the gut have a role in gastrointestinal motility, secretion and sensation.(3) Τ Eluxadoline (Truberzi-Allergan) is a locally acting, mixed opioid receptor agonist/antagonist licensed for the treatment of IBS-D in adults.(4) Here, we consider the evidence for eluxadoline and how it fts with current management strategies for IBS-D...
August 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28798972/diagnostic-precision-of-triage-algorithms-for-mass-casualty-incidents-english-version
#18
A R Heller, N Salvador, M Frank, J Schiffner, R Kipke, C Kleber
BACKGROUND: Regarding survival and quality of life recent mass casualty incidents again emphasize the importance of early identification of the correct degree of injury/illness to enable prioritization of treatment amongst patients and their transportation to an appropriate hospital. The present study investigated existing triage algorithms in terms of sensitivity (SE) and specificity (SP) as well as its process duration in a relevant emergency patient cohort. METHODS: In this study 500 consecutive air rescue missions were evaluated by means of standardized patient records...
August 10, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28736556/ras-signaling-inhibitors-attenuate-disease-in-adjuvant-induced-arthritis-via-targeting-pathogenic-antigen-specific-th17-type-cells
#19
Morad Zayoud, Victoria Marcu-Malina, Einav Vax, Jasmine Jacob-Hirsch, Galit Elad-Sfadia, Iris Barshack, Yoel Kloog, Itamar Goldstein
The Ras family of GTPases plays an important role in signaling nodes downstream to T cell receptor and CD28 activation, potentially lowering the threshold for T-cell receptor activation by autoantigens. Somatic mutation in NRAS or KRAS may cause a rare autoimmune disorder coupled with abnormal expansion of lymphocytes. T cells from rheumatoid arthritis (RA) patients show excessive activation of Ras/MEK/ERK pathway. The small molecule farnesylthiosalicylic acid (FTS) interferes with the interaction between Ras GTPases and their prenyl-binding chaperones to inhibit proper plasma membrane localization...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28736427/ultrasonographic-features-of-the-normal-filum-terminale
#20
Myoungae Kwon, Bo-Kyung Je, Doran Hong, Byung Min Choi
Purpose: The filum terminale (FT) is a fibrous band that connects the conus medullaris to the posterior body of the coccyx. Considering the advances of ultrasonography (US) technology and improvements in the resolution of US images, we aimed to re-establish the US features of the normal FT in infants younger than 6 months of age. Methods: We retrospectively reviewed 30 spinal US scans, stored as video clips. The internal structure of the FT and the marginal echogenicity of the FT were assessed, and transverse and longitudinal US were compared...
June 8, 2017: Ultrasonography
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