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https://www.readbyqxmd.com/read/29134658/-best-practice-for-extracorporeal-photopheresis-in-acute-and-chronic-graft-versus-host-disease-by-societa-italiana-di-emaferesi-and-manipolazione-cellulare-and-gruppo-italiano-trapianto-midollo-osseo-a-national-survey-to-ascertain-its-degree-of-application
#1
Luca Pierelli, Alberto Bosi, Attilio Olivieri
BACKGROUND: A recent "best practice" promoted and published by Gruppo Italiano Trapianto Midollo Osseo (GITMO) and Societa' Italiana di Emaferesi and Manipolazione Cellulare (SIDEM) on the use of extracorporeal photopheresis (ECP) in acute and chronic graft-versus-host disease (GVHD) has been tested for the degree of agreement and application among Italian transplant centers. STUDY DESIGN AND METHODS: Twenty-four Italian centers coordinating a pair number of transplant programs completed the Web-based survey within the fixed deadline, representing approximately 52% of those centers that have a GITMO-accredited allogeneic transplant program that routinely uses ECP in GVHD...
November 13, 2017: Transfusion
https://www.readbyqxmd.com/read/29124710/ultraviolet-irradiation-of-blood-the-cure-that-time-forgot
#2
Michael R Hamblin
Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases including septicemia, pneumonia, tuberculosis, arthritis, asthma and even poliomyelitis. The early studies were carried out by several physicians in USA and published in the American Journal of Surgery. However with the development of antibiotics, UBI use declined and it has now been called "the cure that time forgot". Later studies were mostly performed by Russian workers and in other Eastern countries and the modern view in Western countries is that UBI remains highly controversial...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29121973/in-vitro-investigations-on-extracellular-proteins-secreted-by-aphanomyces-invadans-the-causative-agent-of-epizootic-ulcerative-syndrome
#3
Muhammad Majeed, Gokhlesh Kumar, Sarah Schlosser, Mansour El-Matbouli, Mona Saleh
BACKGROUND: Proteases produced by many microorganisms, including oomycetes, are crucial for their growth and development. They may also play a critical role in disease manifestation. Epizootic ulcerative syndrome is one of the most destructive fish diseases known. It is caused by the oomycete Aphanomyces invadans and leads to mass mortalities of cultured and wild fish in many countries. The areas of concern are Australia, China, Japan, South and Southeast Asian countries and the USA. Extracellular proteases produced by this oomycete are believed to trigger EUS pathogenesis in fish...
November 9, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29118976/impact-of-hormonal-modulation-at-proestrus-on-ovarian-responses-and-uterine-gene-expression-of-suckled-anestrous-beef-cows
#4
Manoel Francisco de Sá Filho, Angela Maria Gonella-Diaza, Mariana Sponchiado, Marcio Ferreira Mendanha, Guilherme Pugliesi, Roney Dos Santos Ramos, Sónia Cristina da Silva Andrade, Gustavo Gasparin, Luiz Lehmann Coutinho, Marcelo Demarchi Goissis, Fernando Silveira Mesquita, Pietro Sampaio Baruselli, Mario Binelli
Background: This study evaluated the impact of hormonal modulation at the onset of proestrus on ovarian response and uterine gene expression of beef cows. Methods: A total of 172 anestrous beef cows were assigned to one of four groups according to the treatment with estradiol cypionate (ECP) and/or equine chorionic gonadotropin (eCG) [CON (n = 43), ECP (n = 43), eCG (n = 44) and ECP + eCG (n = 42)]. Results: ECP-treated cows (ECP and ECP + eCG groups) presented greater occurrence of estrus (44...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29118079/experiences-of-the-kansas-extended-care-permit-providers-a-descriptive-study
#5
Paige M McEvoy, Christopher J Van Ness, Melanie L Simmer-Beck, Bonnie G Branson, Kathy Hunt, Cynthia C Gadbury-Amyot
Purpose: A total of 40 states to date have expanded the role of dental hygienists with the goal of improving access to basic oral health services for underserved populations. In Kansas, legislative changes have resulted in the Extended Care Permit (ECP) designation. The purpose of this study is to describe the experiences of registered dental hygienists in Kansas holding ECP certificates (ECP RDH) as of July of 2014.Methods: Secondary data analysis was performed utilizing data collected from a survey conducted in 2014 by Oral Health Kansas...
August 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29117764/counseling-and-in-advance-provision-of-levonorgestrel-emergency-contraceptive-pills-decrease-the-rate-of-unplanned-pregnancy-during-breastfeeding-a-randomized-controlled-trial
#6
Omar M Shaaban, Ahmed M Abbas, Hanaa R Mahmoud, Entsar M Yones, Shaimaa G Hassen, Mahmoud S Zakherah
OBJECTIVE: To evaluate the effect of counseling and in-advance provision of levonorgestrel emergency contraceptive pills (LNG-ECPs) during postpartum counseling on the incidence of occurrence of unplanned pregnancy during breastfeeding. MATERIALS AND METHODS: The current study is an open-label, parallel, randomized controlled trial carried out in a university hospital in Egypt. All women who delivered and planning to birth-space and breastfeed for at least 1 year were approached for participation during postpartum hospital stay...
November 8, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29105506/genome-based-analysis-of-virulence-determinants-of-a-serratia-marcescens-strain-from-soft-tissues-following-a-snake-bite
#7
Yao-Ting Huang, Jan-Fang Cheng, Yi-Ting Liu, Yan-Chiao Mao, Meng-San Wu, Po-Yu Liu
AIM: Serratia marcescens wound infection after snakebite is often associated with aggressive presentations. However, the virulence determinants remain understudied. MATERIALS & METHODS: Whole-genome sequencing was performed on S. marcescens VGH107, an isolate from wound infection secondary to Trimeresurus mucrosquamatus bite. Comparative genomics approach coupled with multivirulent-locus sequencing typing was applied to systematically predict potential virulence factors...
November 6, 2017: Future Microbiology
https://www.readbyqxmd.com/read/29097224/pharmacy-access-to-ulipristal-acetate-in-major-cities-throughout-the-united-states
#8
Maryssa Shigesato, Jennifer Elia, Mary Tschann, Holly Bullock, Eric Hurwitz, Yan Yan Wu, Jennifer Salcedo
OBJECTIVE: Ulipristal acetate (UPA) is a prescription emergency contraceptive pill (ECP). Despite the potential for UPA to reduce the risk of unintended pregnancies, a recent study in Hawaii demonstrated less than 3% of pharmacies stocked UPA and less than 23% reported the ability to order it. The primary outcome of our study was to assess the availability of UPA in a sample of large cities nationwide. STUDY DESIGN: We conducted a telephone-based secret shopper study of 533 retail pharmacies sampled proportionally from ten large cities in five geographic regions across the US...
October 30, 2017: Contraception
https://www.readbyqxmd.com/read/29086097/an-exploratory-study-of-bdnf-and-oxidative-stress-marker-alterations-in-subacute-and-chronic-stroke-patients-affected-by-neuropathic-pain
#9
Mariacristina Siotto, Irene Aprile, Ilaria Simonelli, Costanza Pazzaglia, Mariacarla Ventriglia, Massimo Santoro, Isabella Imbimbo, Rosanna Squitti, Luca Padua
Patients affected by stroke, particularly subacute stroke patients, often complain of neuropathic pain (NP), which may severely impair their quality of life. The aim of this exploratory study was to characterize NP and to investigate whether there is a correlation between NP and serum brain-derived neurotrophic factor (BDNF) and serum markers of oxidative stress. We enrolled 50 patients divided in subacute (< 90 days from stroke onset) and chronic (> 90 and 180 < days from stroke onset). The Barthel Index, Deambulation Index, and Short Form 36 were used to assess the patients' degree of disability and quality of life...
October 30, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29077182/phacoemulsification-plus-endoscopic-cyclophotocoagulation-versus-phacoemulsification-alone-in-primary-open-angle-glaucoma
#10
Francisco Pérez Bartolomé, Ian A Rodrigues, Saurabh Goyal, Edward Bloch, Wei S Lim, Pouya Alaghband, Jose Guajardo, Stephanie Jones, Kin S Lim
PURPOSE: To examine the efficacy and safety of combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) compared to phacoemulsification alone in patients with primary open-angle glaucoma (POAG). METHODS: We performed a retrospective notes review of 99 consecutive clinical records of patients with POAG from 2 London eye departments. A total of 69 patients who underwent phaco-ECP and 30 sex- and age-matched control patients who underwent cataract surgery alone were included...
October 25, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29069115/the-enhanced-care-program-impact-of-a-care-transition-program-on-30-day-hospital-readmissions-for-patients-discharged-from-an-acute-care-facility-to-skilled-nursing-facilities
#11
Bradley T Rosen, Ronald J Halbert, Kelley Hart, Marcio A Diniz, Sharon Isonaka, Jeanne T Black
BACKGROUND: Increased acuity of skilled nursing facility (SNF) patients challenges the current system of care for these patients. OBJECTIVE: Evaluate the impact on 30-day readmissions of a program designed to enhance the care of patients discharged from an acute care facility to SNFs. DESIGN: An observational, retrospective cohort analysis of 30-day hospital readmissions for patients discharged to 8 SNFs between January 1, 2014, and June 30, 2015...
October 4, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29066479/eosinophil-cationic-protein-in-patients-with-differentiated-thyroid-cancer-treated-with-radioactive-iodine-131
#12
Snezana Zivancevic-Simonovic, Olgica Mihaljevic, Irena Kostic, Nevenka Ilic, Dusan Mihajlovic, Dragan Vasiljevic, Ljiljana Mijatovic-Teodorovic, Svetlana Miletic-Drakulic, Miodrag Colic
Published data indicate the involvement of eosinophil granulocytes and eosinophil cationic protein (ECP) in tumor defense. The aim of this study was to analyze serum ECP concentrations in patients with differentiated thyroid cancer (DTC) before, 3 days and 7 days after radioactive iodine (131-I) therapy. Association of ECP concentrations with histological type of tumor, stage of disease and/or levels of selected T-helper 2 (Th2) cytokines was examined. The study population included 17 DTC patients and 10 control subjects...
September 2017: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29062318/evaluation-of-recombinant-attenuated-salmonella-vaccine-strains-for-broad-protection-against-extraintestinal-pathogenic-escherichia-coli
#13
Jacob T Maddux, Zachary R Stromberg, Roy Curtiss Iii, Melha Mellata
Antibiotic-resistant bacterial infections are difficult to treat, producing a burden on healthcare and the economy. Extraintestinal pathogenic Escherichia coli (ExPEC) strains frequently carry antibiotic resistance genes, cause infections outside of the intestine, and are causative agents of hospital-acquired infections. Developing a prevention strategy against this pathogen is challenging due to its antibiotic resistance and antigenic diversity. E. coli common pilus (ECP) is frequently found in ExPEC strains and may serve as a common antigen to induce protection against several ExPEC serotypes...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29050663/vitamin-d-deficiency-induces-eosinophil-spontaneous-activation
#14
Huiying Lu, Rui-Di Xie, Ritian Lin, Cuicui Zhang, Xiao-Jun Xiao, Lin-Jing Li, Zhi-Qiang Liu, Li-Tao Yang, Bai-Sui Feng, Zhan-Ju Liu, Ping-Chang Yang
Eosinophils (Eo) play a critical role in immunity and immune inflammation. The maintenance of Eo homeostasis is not fully understood yet. Vitamin D (VitD) is involved in the regulation of a large number of biochemical reactions. This study tests a hypothesis that VitD receptor (VDR) contributes to the homeostasis of Eos. In this study, EoL-1 cells (an Eo cell line) were cultured in the presence or absence of calcitriol. The Eo-mediators, including major basic protein (MBP), Eo peroxidase (EPX), Eo cationic protein (ECP) and Eo-derived neurotoxin (EDN), were assessed in the culture supernatant and in EoL-1 cells...
October 12, 2017: Cellular Immunology
https://www.readbyqxmd.com/read/29046095/surgical-placement-of-rectus-sheath-catheters-in-a-cadaveric-cystectomy-model
#15
Ecp Chedgy, G Lowe, R Tang, C Krebs, A Sawka, H Vaghadia, M E Gleave, A I So
Introduction Surgically inserted rectus sheath catheters (RSCs) are used increasingly for analgesia after cystectomy and other abdominal surgery. Currently, there is little information on the optimal positioning of RSCs to allow maximal spread of local anaesthetic. This study sought to assess the spread of dye injected via RSCs and to highlight the extent of its coverage in a fresh unembalmed cadaveric cystectomy model in order to confirm the nerve endings that are likely to be anaesthetised with RSCs. Methods Four cadavers underwent lower midline incision with limited bladder mobilisation...
October 19, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29046070/placenta-previa-without-morbidly-adherent-placenta-comparison-of-characteristics-and-outcomes-between-planned-and-emergent-deliveries-in-a-tertiary-centre
#16
Hadi Erfani, Elias Kassir, Karin A Fox, Steven L Clark, Niloofar Karbasian, Bahram Salmanian, Amir A Shamshirsaz, Jimmy Espinoza, Ahmed A Nassr, Catherine S Eppes, Michael A Belfort, Alireza A Shamshirsaz
OBJECTIVE: To compare patient outcomes between planned and emergent cesarean deliveries for placenta previa without morbidly adherent placenta. STUDY DESIGN: All patients with confirmed, persistent placenta previa (without morbidly adherent placentation) who underwent the surgery between January 2010 and April 2016 were included in this retrospective study. Primary outcome was composite maternal morbidity defined as the presence of at least one of the following: death, red blood cell (RBC) transfusion, hysterectomy, reoperation, hospital stay > 7 days, ureteral injury, bowel injury or cystotomy...
October 18, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29040259/introduction-of-various-allergenic-foods-during-infancy-reduces-risk-of-ige-sensitization-at-12-months-of-age-a-birth-cohort-study
#17
Man-Chin Hua, Tsung-Chieh Yao, Chien-Chang Chen, Ming-Han Tsai, Sui-Ling Liao, Shen-Hao Lai, Chih-Yung Chiu, Kuan-Wen Su, Kuo-Wei Yeh, Jing-Long Huang
BackgroundIn this study, we aimed to determine whether introducing various allergenic foods during infancy is associated with IgE sensitization at 12 months of age.MethodsDetailed information on feeding practices regarding six possible allergenic foods (fruits, egg white, egg yolk, fish, shellfish, and peanuts) was obtained by administering age-specific questionnaires to parents of infants at ages 6 and 12 months. Fecal secretory IgA (sIgA), fecal eosinophil cationic protein (ECP), and serum levels of total IgE and IgE specific to 20 foods, and IgE specific to 20 inhalant allergens were also quantified at 12 months of age...
November 2017: Pediatric Research
https://www.readbyqxmd.com/read/29025546/effusive-constrictive-pericarditis
#18
REVIEW
William R Miranda, Jae K Oh
Effusive-constrictive pericarditis (ECP) corresponds to the coexistence of a hemodynamically significant pericardial effusion and decreased pericardial compliance. The hallmark of ECP is the persistence of elevated right atrial pressure postpericardiocentesis. The prevalence of ECP seems higher in tuberculous pericarditis and lower in idiopathic cases. The diagnosis of ECP is traditionally based on invasive hemodynamics but the presence of echocardiographic features of constrictive pericarditis post-pericardiocentesisis can also identify ECP...
November 2017: Cardiology Clinics
https://www.readbyqxmd.com/read/29019937/a-critical-appraisal-of-extracorporeal-photopheresis-as-a-treatment-modality-for-acute-and-chronic-graft-versus-host-disease
#19
REVIEW
Hind Rafei, Mohamed A Kharfan-Dabaja, Taiga Nishihori
Although significant advances have been made in the biologic understanding of graft-versus-host disease (GVHD) and its treatment options, GVHD remains the single most challenging obstacle to the success of allogeneic hematopoietic cell transplantation (HCT) due to high risk of disabling morbidity and mortality. Extracorporeal photopheresis (ECP) has promising effects in controlling steroid-refractory GVHD, both acute and chronic, and it has been studied extensively. Its putative immunomodulatory mechanisms, while not immunosuppressive, position ECP as an attractive treatment strategy for GVHD patients who are already receiving global immunosuppression...
October 11, 2017: Biomedicines
https://www.readbyqxmd.com/read/28990165/framingham-based-cardiovascular-risk-estimates-among-people-with-episodic-migraine-in-the-us-population-results-from-the-american-migraine-prevalence-and-prevention-ampp-study
#20
Richard B Lipton, Michael L Reed, Tobias Kurth, Kristina M Fanning, Dawn C Buse
BACKGROUND: Cardiovascular (CV) events, conditions, and procedures (ECPs) are common in persons with migraine and are a contraindication to triptan and ergot use. In a prior study, we estimated that there are 2.6 million American adults with episodic migraine (EM) who have had CV ECPs. However, the prior analysis did not assess persons with migraine without CV ECPs who are at high risk for a first cardiovascular disease (CVD) event. OBJECTIVES: To use the Framingham nonlaboratory CVD events risk equation to estimate the number of individuals with EM who are at elevated risk for a first CVD event in the next 10 years using data from the American Migraine Prevalence and Prevention Study, and then to extrapolate the findings to the US population to estimate the scope of people with EM for whom triptan and ergot therapies may be problematic...
October 9, 2017: Headache
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