Eman Abdulfatah, Noah A Brown, Matthew S Davenport, Zachery R Reichert, Sandra I Camelo-Piragua, Amer Heider, Tao Huang, Ulka N Vaishampayan, Stephanie L Skala, Jeffrey S Montgomery, Arul M Chinnaiyan, Samuel Kaffenberger, Pushpinder Bawa, Lina Shao, Rohit Mehra
Extragonadal germ cell tumors (EGCTs) are rare, representing <5% of all germ cell tumors (GCTs). Whilst EGCTs share morphological and immunohistochemical features with their gonadal counterparts, they tend to be more aggressive and are frequently associated with secondary somatic malignancies. The aim of our study was to evaluate the clinical, morphological and immunohistochemical features, and to analyze tumors for chromosomal abnormalities of 12p, in addition to any novel genetic alterations, in a series of EGCTs...
April 30, 2024: Human Pathology