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https://www.readbyqxmd.com/read/28324142/a-phase-ii-study-of-partial-and-subtotal-thymectomy-for-thymoma-jart02
#1
Motoki Yano, Yoshitaka Fujii, Junji Yoshida, Tomoki Utsumi, Hiroyuki Shiono, Motoshi Takao, Masayuki Tanahashi, Yushi Saito
BACKGROUND: We believe the merit of preservation of a part of the thymus following surgery for thymoma. We evaluated the efficacy of partial or subtotal thymectomy for early-stage thymoma in the prospective study. METHODS: The Japanese Association for Research on the Thymus conducted a multiple institutional study of thymectomy for thymoma localized in the thymus without total thymectomy. Patients without autoimmune disease who had an anterior mediastinal tumor that had been clinically diagnosed as an early-stage thymoma were enrolled in the study...
March 21, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28323733/linear-endobronchial-ultrasound-guided-insertion-of-a-fiducial-marker-a-new-tool-for-tracking-central-lesions
#2
Alessio Casutt, Angela Koutsokera, Nicolas Peguret, Alban Lovis
Stereotactic body radiotherapy (SBRT) is an effective method for the treatment of localized primary lung tumors. Cyberknife, a highly accurate SBRT technique, follows the target during respiratory cycles using a metallic fiducial marker (FM) previously inserted into the lesion. Various methods have been described for the placement of an FM in peripheral pulmonary lesions; however, none of these is appropriate for mediastinal or hilar tumors. The placement of FMs in central lesions to achieve accurate SBRT is particularly relevant due to their higher mobility during respiratory and cardiac cycles...
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28314970/-is-surgical-treatment-ever-indicated-in-metastatic-renal-cell-carcinoma-and-if-so-based-on-which-scientific-rationale
#3
M Burger
BACKGROUND: Metastasis is a common event in renal cell carcinoma. Surgical resection of metastases may be feasible in two scenarios: aiming at palliation, which may be feasible due to reduced radiosensitivity of renal cell cancer, and aiming at prolonging survival, which may be feasible given the rather good prognosis of some patterns of metastasis. OBJECTIVE: This review intends to reflect on current evidence for surgical resection of metastases in both scenarios...
March 17, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28306215/primary-mediastinal-and-retroperitoneal-malignant-germ-cell-tumors-in-children-and-adolescents-results-of-the-tgm95-trial-a-study-of-the-french-society-of-pediatric-oncology-soci%C3%A3-t%C3%A3-fran%C3%A3-aise-des-cancers-de-l-enfant
#4
Hélène Sudour-Bonnange, Cécile Faure-Conter, Hélène Martelli, Frederic Hameury, Brice Fresneau, Daniel Orbach, Cécile Vérité
PURPOSE: To examine the clinical presentation, treatment and results in children and adolescents with primary mediastinal (PM) and retroperitoneal (RP) germ cell tumors (GCTs). METHODS: The TGM95 trial for malignant GCTs was conducted in France between 1995 and 2005 to evaluate a strategy adapted to prognostic factors with cisplatin-based chemotherapy and surgical management. We reviewed patients with TGCTs at PM and RP sites. RESULTS: Among 239 patients, there were 16 patients with PM and 5 with RP tumors, which represent 9% of all patients, highlighting the rarity of these extragonadal locations...
March 17, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28302232/giant-ganglioneuroma-in-a-5-year-child
#5
Fazal Wahab Khan, Saulat Hasnain Fatimi, Hamza Abdur Rahim Khan
We report a 5-year boy presenting with pain in the lower chest and upper abdomen. On evaluation with computed tomography scan of the chest, he was found to have a large 16 x 14 cm posterior mediastinal mass compressing the inferior vena cava and liver, and shifting the heart to the opposite side. Tumor was approached via right postero-lateral thoracotomy and dissected off from esophagus, heart, inferior vena cava and lungs. The entire tumor was resected without any complications. Postoperative course was unremarkable...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28294675/-tumor-of-posterior-mediastinum-rare-case-of-extramedullar-myelolipoma
#6
Tamás Zombori, Noémi Tóth, József Furák, Zsolt Berényi, László Tiszlavicz
CASE REPORT: A 71-year-old male with acute exacerbation of chronic bronchitis was treated in summer of 2015. The CT scan has revealed a mass on the right side of 11th thoracic vertebra in the adipose tissue with a sharp edge towards the lung and containing a small amount of contrast agent. The radiologist recommended histological sampling of the mass. The tumor was removed by Video-Assisted Thoracic Surgery (VATS) in August of 2015. The patient was discharged on the fifth postoperative day without complication...
March 2017: Magyar Sebészet
https://www.readbyqxmd.com/read/28293535/inflammatory-choroidal-neovascular-membrane-after-healed-tuberculous-choroidal-granuloma
#7
Sikander A K Lodhi, Khadija Saifuddin, Santhosh Devulapally
Objective: To present a case of choroidal granuloma masquerading as intraocular tumor that healed on anti-tuberculous treatment but led to the development of inflammatory choroidal neovascular membrane (CNVM). Method: A 42-year-old female patient with past history of hysterectomy presented with diminution of vision in the right eye. Fundus examination in the right eye showed a yellowish white choroidal mass with associated bullous retinal detachment superotemporal to fovea. Left eye fundus was normal. Fundus flourescein angiography showed early and late hyperflourescence with late pooling in serous detachments...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28293012/-synchronous-triple-primary-lung-adenocarcinomas-one-of-which-showing-a-thin-walled-cavity-nodule-report-of-a-case
#8
Takefumi Doi, Toshihiko Sakamoto
A 74-year-old woman was referred to our hospital to investigate a right apical segment (S1)nodule which was increasing gradually. Chest computed tomography (CT) scan showed three lesions in right S1, posterior segment(S2) and superior segment(S6). S6 lesion was a thin-walled cavity enlarging gradually with same appearance. The S1 nodule was diagnosed as adenocarcinoma by CT guided biopsy. Since the possibility of lung cancer couldn't be denied for S6 lesion, right upper lobectomy and S6 segmentectomy with mediastinal lymph node dissection was performed...
March 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28292994/-a-recurrent-case-of-thymic-adenocarcinoma-effectively-treated-with-s-1-over-a-long-term-period
#9
Munehisa Takata, Isao Matsumoto, Yusuke Tanaka, Daisuke Saito, Shuhei Yoshida, Seiichi Kakegawa, Masaya Tamura, Hirofumi Takemura, Hiroko Ikeda
A 61-year-old woman with an abnormal radiograph shadow in her anterior mediastinum was admitted to our hospital and underwent an extended thymectomy. The pathological diagnosis of the tumor was a non-papillary adenocarcinoma of the thymus in pathological stage IV b using the Masaoka classification owing to mediastinal lymph node metastasis. We found parasternal lymph node metastases 5 months after her first operation, and subsequently, she underwent surgery and adjuvant radiotherapy. We found systemic lymph node metastases and metastatic lesions in distant organs, including her lungs, brain, and kidney 27 months after her first operation...
March 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28291005/the-correlation-between-pre-treatment-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-parameters-and-clinical-prognostic-factors-in-pediatric-hodgkin-lymphoma
#10
Ebru Tatcı, İnci Uslu Biner, Suna Emir, Hikmet Gülşah Tanyıldız, Özlem Özmen, Engin Alagöz, Atila Gökçek, Gürses Şahin
OBJECTIVE: To compare standardized uptake values (SUV) derived from pre-treatment (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging and clinical prognostic factors in pediatric patients with Hodgkin lymphoma (HL). METHODS: Pre-treatment FDG PET/CT findings of 28 children with HL were evaluated in this retrospective study. Metabolic tumor volume (MTV), SUVmax normalized by weight (SUVweight), lean body mass (SUVlbm), body surface area (SUVbsa) and plasma glucose levels of tumors (SUVglucose) were calculated using pre-treatment FDG PET/CT scan images...
February 5, 2017: Molecular Imaging and Radionuclide Therapy
https://www.readbyqxmd.com/read/28288537/exit-procedure-for-fetal-mediastinal-teratoma-with-large-pericardial-effusion-a-case-report-with-review-of-literature
#11
Arpit Agarwal, Eliot Rosenkranz, Salih Yasin, Sethuraman Swaminathan
BACKGROUND: Large mediastinal teratomas in the fetus are rare and can present with direct compression of intrathoracic structures as well as pericardial and pleural effusions. Mediastinal fetal teratoma may be detected as a mass in the chest during a routine prenatal ultrasound. Because of the pressure on mediastinal structures it may result in non-immune fetal hydrops and polyhydramnios. The development of hydrops may lead to fetal demise. Timely obstetric and surgical removal is important to improve survival in this patient population...
March 13, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28267977/indications-for-adjuvant-mediastinal-radiotherapy-in-surgically-resected-small-cell-lung-cancer
#12
Elliot Wakeam, Meredith Giuliani, Natasha B Leighl, Samuel R G Finlayson, Thomas K Varghese, Gail E Darling
BACKGROUND: Adjuvant mediastinal radiotherapy (AMR) is used after surgical resection for patients with small cell lung cancer (SCLC), but data guiding its use are scant. We sought to examine whether AMR was associated with an improvement in survival for resected SCLC patients and to define subpopulations who should be selected for AMR. METHODS: Patients undergoing lobectomy, pneumonectomy, and sublobar resection for SCLC were identified in the National Cancer Database (2004 to 2013)...
March 3, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28266295/simultaneous-total-esophagectomy-and-anterior-mediastinal-tracheostomy-for-recurrent-laryngeal-cancer-extended-to-the-superior-mediastinum
#13
Marius Fodor, Marcel Cosgarea, Lucian Fodor
Recurrent laryngeal cancer has an incidence of 25-50% and a 23-35% fiveyear survival rate. Surgery is the best treatment in order to control local recurrence. Herein, we present our surgical strategy for a patient with a history of modified radical laryngectomy for laryngeal cancer and with recurrent tumor at the cervical tracheostomy site extended to the thoracic trachea and esophagus. The wide resection included the sternal manubrium, the upper thoracic trachea, the entire esophagus and the upper mediastinal lymph nodes...
January 2017: Chirurgia
https://www.readbyqxmd.com/read/28265216/right-thoracoabdominal-approach-for-retrocardiac-paraganglioma-resection
#14
Carlos A Hinojosa, Hugo Laparra-Escareno, Javier E Anaya-Ayala, Rene Lizola, Adriana Torres-Machorro, Armando Gamboa-Domínguez
Paragangliomas are rare extra-adrenal tumors of sympathetic or parasympathetic paraganglia origin; of these, mediastinal paragangliomas are 2% of all cases. We present the case of a 21-year-old woman with uncontrolled arterial hypertension who had a functioning 6.5 × 6.2-cm retrocardiac paraganglioma firmly attached to the pericardium. The patient underwent tumor resection via a right thoracoabdominal incision; this surgical approach enabled adequate exposure for complete resection without institution of cardiopulmonary bypass or need for cardiac reconstruction or autotransplantation...
February 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28263419/transoral-ultrasonic-surgery-of-pharyngolaryngeal-giant-hemangioma-after-ethylene-vinyl-alcohol-copolymer-onyx-embolization
#15
Meritxell Valls-Mateus, Luis San Román, Juan Macho, Alfons Nadal, Manuel Bernal-Sprekelsen, Isabel Vilaseca
BACKGROUND: Cervico-mediastinal hemangiomas in adulthood are rare and slow-growing vascular tumors. The optimal treatment for giant hemangiomas is controversial. In asymptomatic cases, clinical observation is generally recommended. METHODS: We report the transoral resection of a pharyngolaryngeal hemangioma (diameters of 44 × 56 × 39 mm) with tracheal involvement and mediastinal extension. Clinically, the patient had throat foreign body sensation, severe dyspnea and stridor...
March 6, 2017: Head & Neck
https://www.readbyqxmd.com/read/28256438/size-measurement-and-t-staging-of-lung-adenocarcinomas-manifesting-as-solid-nodules-%C3%A2-30%C3%A2-mm-on-ct-radiology-pathology-correlation
#16
Benedikt H Heidinger, Kevin R Anderson, Eoin M Moriarty, Daniel B Costa, Sidhu P Gangadharan, Paul A VanderLaan, Alexander A Bankier
RATIONALE AND OBJECTIVES: This study aimed to compare long-axis diameter to average computed tomography (CT) diameter measurements of lung adenocarcinomas manifesting as solid lung nodules ≤30 mm on CT, as referenced to pathologic measurements, and to determine the impact of the two CT measurement approaches on tumor (T)-staging of nodules. MATERIALS AND METHODS: This institutional review board-approved study included all 274 radiologic solid adenocarcinomas resected at our institution over 10 years...
February 27, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28256095/effect-of-visceral-pleural-invasion-on-the-prognosis-of-patients-with-lymph-node-negative-non-small-cell-lung-cancer
#17
Dan Tian, Yuquan Pei, Qingfeng Zheng, Jianzhi Zhang, Shaolei Li, Xing Wang, Dongmei Lin, Yue Yang
BACKGROUND: Visceral pleural invasion (VPI) is an adverse prognostic factor in non-small cell lung cancer (NSCLC); however, its effect in relation to tumor size remains under debate. To better understand the prognostic impact and potential consequences for staging, we examined correlations between VPI and clinicopathologic characteristics in patients with NSCLC, particularly those with lymph node negative NSCLC. METHODS: We retrospectively analyzed 813 cases of radically resected NSCLC treated in our institution between December 2005 and December 2011...
March 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28248868/epithelioid-hemangioendothelioma-of-right-innominate-vein-mimics-a-teratoma-a-case-report
#18
Qi Wan, Jiaxuan Zhou, Yudong Yu, Qingyu Sun, Yingying Bao, Qiang Lei, Qiao Zou, Yingshi Deng, Xinchun Li
RATIONAL: Epithelioid hemangioendothelioma (EHE) is a rare neoplasm commonly known to arise from the soft tissue, lung, and liver. EHE arising from right innominate vein (RIV) has scarcely been reported in English literature. PATIENT CONCERNS: Herein, we present a rare case of EHE of RIV in a 51-year-old woman with right-lower chest pain for 4 days. Computed tomography of the chest revealed a spherical mass with calcification and fatty foci located in the anterior mediastinum, thus a presumptive diagnosis of teratoma was made...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28242989/detection-of-thymoma-on-99mtc-mibi-scintigraphy-revisiting-the-past
#19
Girish Kumar Parida, Shambo Guha Roy, Anshul Sharma, Chetan D Patel
Although thymoma is a rare tumor, it is the most common anterior mediastinal tumor, usually affecting the adults in their fifth and sixth decade. We present a case of 68-year-old man with history of myocardial infarction, who presented to the cardiology OPD with recent onset of exertional dyspnea. On 99mTc MIBI myocardial perfusion SPECT, there was an extra cardiac accumulation of radiotracer in the anterior mediastinum just above the heart, which later was diagnosed as thymoma on histopathology.
January 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28242092/-cutaneous-involvement-in-t-lymphoblastic-lymphoma
#20
C Nascimbeni, S Chantepie, C Brugiere, F Comoz, V Salaun, L Verneuil
BACKGROUND: Lymphoblastic lymphoma (LBL) is a rare form of non-Hodgkin's lymphoma (NHL). Cutaneous LBL is seen in less than 20% of patients. PATIENTS AND METHODS: Herein, we report the case of a 66-year-old male patient without any previous disease history of note and who was presenting a gradually spreading tumoral lesion of the scalp, several purplish macules and nodules on the trunk, and a single spinal adenopathy. A thoracic-abdominal-pelvic CT scan performed for acute renal failure, revealed extensive infiltration of retroperitoneal tissue...
February 24, 2017: Annales de Dermatologie et de Vénéréologie
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