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D M Burger, M W L van der Cruijsen, R Schim van der Loeff
This issue of the Dutch Journal of Medicine (NTvG) features a review article by Van der Veen et al. on safe administration of medicines in hospitals. This topic is part of an increased focus on patient safety that started at the beginning of the 21st century, following publication of the renowned report 'To err is human'. Now, almost 20 years later, we are a little disappointed that there is still no set of interventions that can be implemented to guarantee safe administration of medicines in hospitals. Why ever not? In this commentary we discuss the main limitations of the interventions that have been studied, but also describe what we think can already be implemented without further research...
2017: Nederlands Tijdschrift Voor Geneeskunde
D M Burger
- In a previous issue, a case report was presented in the Dutch Journal of Medicine (NTvG) of a patient who had variable clozapine levels after switching from regular cigarettes to an e-cigarette and vice versa.- Besides clozapine there are a number of other agents with a narrow therapeutic range where pharmacokinetics can be influenced by smoking.- This review describes the mechanisms of smoking-induced influence on the pharmacokinetics of medicines, and guidance will be provided regarding which medicines must be monitored more closely when patients change their smoking habits...
2017: Nederlands Tijdschrift Voor Geneeskunde
N H Chavannes
In a systematic review in the Dutch Journal of Medicine (NTvG), Dallinga et al. look for an answer to the societally relevant question of whether mobile apps are proven to lead to a more active and healthy lifestyle. Decision makers in healthcare have high expectations of eHealth, a field where scientific evidence sometimes seems overruled merely by the opinions of self-declared 'futurists'. Commonly, eHealth is propelled forward as the solution to the lack of manpower in healthcare, given the expected rise of chronic disease...
2016: Nederlands Tijdschrift Voor Geneeskunde
Timo C Bolt
Over the past half century, medicine has evolved into 'informational medicine'. Physicians today no longer necessarily have to possess specialist knowledge, but have to know how to access this knowledge. This means that it is important that they do not just 'grab' for loose bits of information, but systematically and judiciously search for relevant knowledge. Medical-historical insights could be helpful, alongside critical-appraisal skills. Medical knowledge has a certain structure that has developed historically under the influence of assumptions (some implicit), presuppositions and social forces and interests...
2016: Nederlands Tijdschrift Voor Geneeskunde
Gerrit-Jan Liefers, Esther Bastiaannet
In this issue of the Dutch Journal of Medicine (NTvG), Saadatmand and colleagues report the results of a large retrospective study on breast cancer patients in the Netherlands. One of their conclusions is that breast-conserving therapy results in better survival compared to breast amputation. Here we argue that retrospective studies are not designed to draw any conclusions with regard to outcome. Confounding by indication is the main reason why differences in outcome may not be causally connected in the context of retrospective data...
2016: Nederlands Tijdschrift Voor Geneeskunde
Marcel Verheij, Neil K Aaronson
The paper by Kunneman and colleagues published in the Dutch Journal of Medicine (NTvG) touches upon a timely and important health care issue: shared decision-making. The study focused on the adequacy of the information given to patients by their treating radiation oncologists before undergoing preoperative radiotherapy for rectal cancer. The main conclusion of this study is that there is a wide variation in the quantity and quality of the information given regarding the advantages and disadvantages of this treatment...
2015: Nederlands Tijdschrift Voor Geneeskunde
Bob Siegerink, Olaf M Dekkers, Frits R Rosendaal
Learning to conduct good research demands a considerable investment in terms of time from a young investigator but this is sometimes difficult to achieve alongside studying or training. In 1989, the Dutch Journal of Medicine (NTvG) printed a 'recipe' for conducting a clinical research training project, which made some recommendations for the successful completion of such a project even with limited time and resources. This article reviews these three recommendations and adds another two. The final recommendations are: limit the research question, conduct a pilot study, write the article before you collect the data, streamline the research process and be accountable...
2015: Nederlands Tijdschrift Voor Geneeskunde
Yolanda van der Graaf, Joost Zaat
Keeping up with the latest developments is not easy, but neither is reading articles on research. There are too many medical journals that contain information that is irrelevant to clinical practice. From this mass of articles you have to decide which are important for your own clinical practice and which are not. Most articles naturally fall into the latter category as spectacular findings with important consequences for medical practice do not occur every week. The most important thing in a research article is the research question...
2015: Nederlands Tijdschrift Voor Geneeskunde
Theo A Boer
A survey published in the Dutch Journal of Medicine (NTvG) shows that doctors asked to assess the suffering of patients making a request for euthanasia may give very different opinions. In this paper, I argue that this stems from the subjective character of the term 'unbearable' and that differences are bound to occur even more frequently in 'borderline' cases, such as those presented here. In my opinion, such differences do not justify a plea to abandon the assessment of unbearable suffering altogether. Rather, differences in assessment may serve as indications that the boundaries of the Dutch law on euthanasia and physician-assisted suicide are within sight...
2015: Nederlands Tijdschrift Voor Geneeskunde
Marcel T Adriaanse, Pieter van Eijsden, Peter W de Leeuw
E-learning is a popular method of continuous medical education (CME) which is becoming increasingly available to doctors. A specific form of E-learning is an online knowledge test accompanying a journal article. CME accreditation points can be obtained by reading an article and then answering test questions on it. This is a user-friendly form of CME which an increasing number of journals are offering as a service to their readers. The Dutch Journal of Medicine (NTvG) has been offering accredited tests to its readers since 2011...
2014: Nederlands Tijdschrift Voor Geneeskunde
Margo J Trappenburg
Dutch Journal of Medicine (NTVG) Lecture 2013: Organized solidarity in a welfare state is impersonal, restricted and based on enlightened self-interest. Critics of the welfare state argue that it is obsolete and we should aim for a society based on individual participation. They believe that people now prefer individualized care, that it is no longer possible to set boundaries and that too much altruism is required from those with higher incomes. In this year's NTvG lecture Margo Trappenburg contended that this criticism is unjust...
2013: Nederlands Tijdschrift Voor Geneeskunde
M H T M Haerkens, E C T H Tan, E Lely
This is a commentary on the article entitled 'Dutch military casualties of the war in Afghanistan - Quality of life and level of participation after rehabilitation' by de Kruijff and colleagues, published in the Dutch Journal of Medicine (Nederlands Tijdschrift voor Geneeskunde, NTvG). The article addresses a very relevant issue: the impact of war injuries on a wounded soldier's recovery, quality of life and level of participation after rehabilitation. The choice was made to compare soldiers wounded during their mission in Uruzgan with the Dutch general trauma population by means of the 'Injury Severity Score' (ISS) and the 'Abbreviated Injury Scale' (AIS) score...
2012: Nederlands Tijdschrift Voor Geneeskunde
G Kenter, S Wijma
In light of the 125th anniversary of the Dutch Society of Obstetrics and Gynaecology (NVOG), the Netherlands Journal of Medicine (NTvG) will publish a series of articles over the coming months. The articles will cover various topics from the specialty areas of gynaecology and obstetrics. We hope that these articles will inspire you, so that, in another 25 years, we can report again on positive developments of our specialty for patients, doctors and the community.
2012: Nederlands Tijdschrift Voor Geneeskunde
Tanja G M Vrijkotte, Marieke L A de Hoog, Manon van Eijsden
Recently, the guideline for prevention, screening and intervention in respect of overweight in children for the Youth Health Care practice has been published in an abbreviated form in NTvG. Childhood overweight is an important public health problem that requires preventive actions from early age onwards, especially in immigrant groups. Although this guideline provides a basis for (preventive) actions within Youth Health Care, the author argues that a community based approach including specific prevention and intervention strategies for ethnic groups is needed for successful implementation...
2012: Nederlands Tijdschrift Voor Geneeskunde
Annelies E van Eeden, Rachel E J Roach, Nynke Halbesma, Friedo W Dekker
OBJECTIVE: To determine and compare the foundation of claims in drug-promoting advertisements in a Dutch journal for physicians and a Dutch journal for pharmacists. DESIGN: A cross-sectional study. METHOD: We included all the drug-promoting advertisements referring to a randomized controlled trial (RCT) we could find on Medline from 2 volumes of the Dutch Journal of Medicine (Nederlands Tijdschrift voor Geneeskunde; NTvG) and the (also Dutch) Pharmaceutical Weekly (Pharmaceutisch Weekblad; PW)...
2012: Nederlands Tijdschrift Voor Geneeskunde
Eline L M Op de Coul, Susan Hahné, Yolanda W M van Weert, Petra Oomen, Colette Smit, Kitty P B van der Ploeg, Daan W Notermans, Kees Boer, Marianne A B van der Sande
BACKGROUND: A screening programme for pregnant women has been in place since the 1950s in the Netherlands. In 2004 universal HIV screening according to opting out was implemented. Here, we describe the evaluation of the effectiveness of antenatal screening in the Netherlands for 2006-2008 for HIV, hepatitis B virus (HBV) and syphilis in preventing mother-to-child transmission, by using various data sources. METHODS: The results of antenatal screening (2006-2008) were compared with data from pregnant women and newborns from other data sources...
2011: BMC Infectious Diseases
T O H de Jongh, J O M Zaat
This article is the introduction to a new series in the Nederlands Tijdschrift voor Geneeskunde about the value of physical examination. Associated with this series, on the website ( there are chapters of the new textbook on physical examination and films about carrying out physical examinations. Although physical examination is an essential part of the diagnostic process, often little attention is paid to the correct execution of the examination and there is insufficient knowledge of the value of the findings...
2010: Nederlands Tijdschrift Voor Geneeskunde
(no author information available yet)
Podcasts become increasingly available for many biomedical journals. Since the beginning of this year the Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine) has been uploading podcasts on a weekly basis. With this the journal offer its readers audio summaries and interviews with authors for free (
June 21, 2008: Nederlands Tijdschrift Voor Geneeskunde
P W de Leeuw
The editor in chief, J. van Gijn, has retired. His main emphasis on the generalist capacities of the physician and on meticulous anamnesis and thorough physical examination is as relevant as ever. However a new challenge is unfolding: how to serve the modern physician who was brought up with digital information and the Internet revolution, with relevant, independent, and objective medical information. The web presence of this journal ( will be brought up to the level of the demanding modern physician...
January 5, 2008: Nederlands Tijdschrift Voor Geneeskunde
H E Menke, R J B Wille, W R Faber, T Pieters
OBJECTIVE: To determine the Dutch contributions to the formulation of the concept that leprosy is an infectious disease. DESIGN: Literature study. METHOD: A search for relevant publications was made in the Nederlands Tijdschrift voor Geneeskunde (Dutch journal of Medicine; NTvG) and the Geneeskundig Tijdschrift voor Nederlandsch-Indië (Medical Journal of the Dutch Indies; GTNI) with the aid of the search terms 'lepra [leprosy]', 'lepra Arabum [Arab leprosy]', 'melaatsheid [leprosy]' and 'elephantiasis Graecorum [Greek elephantiasis]'...
April 7, 2007: Nederlands Tijdschrift Voor Geneeskunde
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