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https://www.readbyqxmd.com/read/29034411/impact-of-corneal-donor-lens-status-on-two-year-course-and-outcome-of-descemet-membrane-endothelial-keratoplasty-dmek
#1
Friederike Schaub, Layla Pohl, Philip Enders, Werner Adler, Björn O Bachmann, Claus Cursiefen, Ludwig M Heindl
PURPOSE: Our purpose was to investigate the impact of lens status of corneal donors on the two-year course and clinical outcome of Descemet membrane endothelial keratoplasty (DMEK). METHODS: In 181 DMEK surgeries, 136 phakic and 45 pseudophakic donor corneas were grafted. In this retrospective audit we compared the lens status of corneal donors regarding the outcome measures best spectacle-corrected visual acuity (BSCVA), central corneal thickness (CCT), and endothelial cell density (ECD) at 1, 3, 6, 12, and 24 months, as well as intra- and postoperative complication rates and graft detachment rates requiring re-bubbling...
October 15, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29034157/endoscope-assisted-vitrectomy-in-the-management-of-retinal-detachment-with-corneal-opacity
#2
Yu-Fang Huang, Chia-Jen Chang
A 51-year-old male who had suffered from right eye rhegmatogenous retinal detachment with proliferative vitreoretinopathy received surgical treatments which included the following procedures: lens extraction, scleral buckle, vitrectomy, membrane peeling, photocoagulation, and silicone oil injection. The presenting visual acuity of the right eye was light perception. Slit-lamp examination revealed corneal opacity without a visible fundus. B-scan ultrasonography revealed retinal detachment. Endoscope-assisted vitrectomy was then performed in December 2014...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032414/influence-of-lasek-on-schi%C3%A3-tz-goldmann-and-dynamic-contour-tonometry
#3
Marco Sales-Sanz, Esther Arranz-Marquez, Carolina Arruabarrena, Miguel A Teus
PURPOSE: Our purpose was to assess the effect of LASEK surgery on ocular rigidity and to compare its effect on intraocular pressure (IOP) readings with Goldmann applanation tonometry (GAT), Schiøtz indentation tonometry (ST) and dynamic contour tonometry (DCT). METHODS: Prospective, observational, single-masked cohort study. One eye per patient from 31 consecutive subjects who underwent LASEK refractive surgery to correct myopia, as well as from 108 non-operated myopic patients, were included...
October 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29032195/global-causes-of-blindness-and-distance-vision-impairment-1990-2020-a-systematic-review-and-meta-analysis
#4
Seth R Flaxman, Rupert R A Bourne, Serge Resnikoff, Peter Ackland, Tasanee Braithwaite, Maria V Cicinelli, Aditi Das, Jost B Jonas, Jill Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Alex Silvester, Gretchen A Stevens, Nina Tahhan, Tien Y Wong, Hugh R Taylor
BACKGROUND: Contemporary data for causes of vision impairment and blindness form an important basis of recommendations in public health policies. Refreshment of the Global Vision Database with recently published data sources permitted modelling of cause of vision loss data from 1990 to 2015, further disaggregation by cause, and forecasts to 2020. METHODS: In this systematic review and meta-analysis, we analysed published and unpublished population-based data for the causes of vision impairment and blindness from 1980 to 2014...
October 10, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/29032110/use-of-donors-predisposed-by-corneal-collagen-cross-linking-in-penetrating-keratoplasty-for-treating-the-patients-with-keratoconus
#5
Ting Huang, Ruifen Ye, Chen Ouyang, Chao Hou, Yunwei Hu, Qianni Wu
PURPOSE: To investigate whether use of donors predisposed by corneal collagen cross-linking (CXL) reduced myopic refractive errors for keratoconic eyes after penetrating keratoplasty (PK). DESIGN: Randomized controlled trial. METHODS: One hundred sixteen eyes of 116 patients with keratoconus from Zhongshan Ophthalmic Center were enrolled. Using stratified block randomization, eligible eyes were assigned to CXL graft group (Group1) or conventional graft group (Group2)...
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29030303/electrospun-formulations-of-bevacizumab-for-sustained-release-in-the-eye
#6
Ukrit Angkawinitwong, Sahar Awwad, Peng T Khaw, Steve Brocchini, Gareth R Williams
Medicines based on vascular endothelial growth factor (VEGF) neutralising antibodies such as bevacizumab have revolutionized the treatment of age related macular degeneration (AMD), a common blinding disease, and have great potential in preventing scarring after surgery or accelerating the healing of corneal injuries. However, at present, frequent invasive injections are required to deliver these antibodies. Such administration is uncomfortable for patients and expensive for health service providers. Much effort is thus focused on developing dosage forms that can be administered less frequently...
October 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29022296/efficacy-and-safety-of-intracameral-bevacizumab-for-treatment-of-neovascular-glaucoma
#7
Jun Young Ha, Mi Sun Sung, Sang Woo Park
PURPOSE: To evaluate the long-term efficacy and safety of intracameral bevacizumab in patients with neovascular glaucoma. METHODS: This retrospective study included 26 eyes of 26 neovascular glaucoma patients who received intracameral bevacizumab injection between January 2013 and May 2015, and were followed-up for at least 1 year. All patients were treated with topical and/or systemic intraocular pressure (IOP)-lowering medications, intracameral bevacizumab, and panretinal photocoagulation (PRP)...
August 26, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/29018764/scleral-buckling-induced-ocular-parameter-changes-in-different-age-group-patients-of-rhegmatogenous-retinal-detachment
#8
Ashish Bedarkar, Ratnesh Ranjan, Perwez Khan, Ramesh Chandra Gupta, Rajnath Kushwaha, Shalini Mohan
PURPOSE: This study was aimed to evaluate the difference in the ocular parameter changes following scleral buckling (SB) for rhegmatogenous retinal detachment (RRD) in different age group patients. MATERIALS AND METHODS: This prospective study included 26 eyes of 26 patients who underwent SB for uncomplicated RRD. The patients were divided into three age groups: 16-30 years (Group I), 31-45 years (Group II), and 46-60 years (Group III). Axial length (AL), anterior chamber depth (ACD), and corneal curvatures were measured preoperatively and postoperatively at 1 week, 1 month, and 3-month...
April 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29018756/descemet-s-stripping-automated-endothelial-keratoplasty-for-symptomatic-thioridazine-deposits-in-the-cornea
#9
Masoumeh Mohebbi, Hassan Hashemi, Alireza Mahmoudi, Pasha Anvari
The aim of this study was to use Descemet's Stripping-automated Endothelial Keratoplasty (DSAEK) as a novel treatment to remove thioridazine corneal deposits. A 53-year-old female presented with a 3-month history of visual loss and glare. She had been taking thioridazine (100 mg/day for 1 year) for a psychiatric disorder. Dense yellowish-brown deposits had developed in the posterior stroma. Thioridazine was discontinued, and she was switched to fluoxetine. One year after discontinuation of thioridazine, her symptoms and signs did not resolve...
January 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/28993355/bilateral-fungal-keratitis-with-ring-infiltrates-a-rare-scenario
#10
Manthan Hasmukhbhai Chaniyara, Amar Pujari, Jayanand Urkude, Namrata Sharma
A 12-year-old boy presented to the emergency department with chief complaints of pain, redness, discharge and diminution of vision in both eyes over the previous 20 days. There was no history of preceding trauma, contact lens use, any eye drop usage or ocular surgery. Systemic history was not significant. Presenting uncorrected visual acuity in his right eye was counting fingers at 1 m and 20/200 in the left eye, with accurate projection of rays in both eyes. Slit lamp biomicroscopy showed the presence of bilateral diffuse conjunctival congestion, corneal ring infiltrates and epithelial defect with corneal oedema...
October 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28993070/the-effect-of-soft-contact-lens-thickness-in-visual-function-after-intracorneal-ring-segments-surgery
#11
G Carracedo, J Canales, P Gonzalez, A Rechionni, C Carpena-Torres, J Carballo-Álvarez
OBJECTIVE: To study the influence of soft contact lens (SCL) central thickness and material in keratoconus on visual function after intracorneal ring segment (ICRS) surgery. METHODS: A pilot, experimental, prospective, cross-sectional and double-blind study was performed. Fourteen keratoconus patients with age range of 34.75±9.22years (7 males and 7 females) with ICRS implanted were involved in the study. Two different SCL materials [Hioxifilcon A (G-5X/p-GMA/HEMA) and Lucifilcon A (silicone-hydrogel)] with four different central thicknesses (0...
October 6, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28991853/simulated-keratometry-versus-total-corneal-power-by-ray-tracing-a-comparison-in-prediction-accuracy-of-intraocular-lens-power
#12
Giacomo Savini, Kenneth J Hoffer, Domenico Schiano Lomoriello, Pietro Ducoli
PURPOSE: To investigate the relationship between corneal powers measured by simulated keratometry (Sim-K) and ray tracing and understand whether their difference influences intraocular lens (IOL) power calculation. METHODS: In a first sample of healthy eyes, corneal curvature was measured using a rotating Scheimpflug camera (Sirius, CSO). Sim-K was obtained from anterior corneal curvature using the 1.3375 keratometric index. Ray tracing was performed through both corneal surfaces to calculate the total corneal power (TCP)...
November 2017: Cornea
https://www.readbyqxmd.com/read/28991852/preparation-and-biomechanical-properties-of-an-acellular-porcine-corneal-stroma
#13
Qing Li, Hongmei Wang, Zhenye Dai, Yichen Cao, Chuanyu Jin
PURPOSE: To construct an acellular porcine corneal stroma (aPCS) as a human corneal stroma alternative and to further explore its biomechanical properties. METHODS: A combination of DNA-RNA enzymes and ultrasound technology was used to strip the native porcine corneal cells. The microstructure of aPCS was observed by H&E staining, DAPI staining, and α-Gal tests. The mechanical properties were detected by a tension machine. Cytotoxicity of aPCS was measured by the MTT assay...
November 2017: Cornea
https://www.readbyqxmd.com/read/28991621/central-island-formation-after-cataract-surgery-in-a-laser-in%C3%A2-situ-keratomileusis-eye-new-etiology
#14
Sylvain El-Khoury, Youssef Abdelmassih, George Cherfan, Johnny M Khoury
We report a case of central corneal steepness formation after cataract surgery in a post-laser in situ keratomileusis (LASIK) eye. A 51-year-old woman with traumatic cataract and a history of myopic LASIK surgery had uneventful phacoemulsification cataract surgery. Postoperatively, the corneal topography difference map showed a central island formation of 2.1 diopters (D) compared with the preoperative level, which correlated with a clinical myopic shift of 2.00 D from the targeted emmetropia. At 4 months, most of the central island had resolved spontaneously...
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28991620/new-perspectives-on-the-detection-and-progression-of-keratoconus
#15
REVIEW
Antonio Martínez-Abad, David P Piñero
Laser refractive surgery has increased markedly in recent years, making the detection of corneal abnormalities extremely relevant. For this reason, an accurate diagnosis of clinical or subclinical keratoconus is critical. Corneal topography is the primary diagnostic tool for keratoconus detection, and pachymetry data and corneal aberrations are also commonly used. Recently, tomographic measurements using optical coherence tomography and corneal biomechanical indices have been used. In incipient and subclinical keratoconus, the use of a single parameter as a diagnostic factor is not sufficiently accurate...
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28991610/intraocular-lens-power-calculation-for-eyes-with-high-and-low-average-keratometry-readings-comparison-between-various-formulas
#16
Olga Reitblat, Adi Levy, Guy Kleinmann, Tsahi T Lerman, Ehud I Assia
PURPOSE: To compare the accuracy of intraocular lens power prediction for eyes with average keratometry (K) readings greater than 46.00 diopters (D) and lower than 42.00 D. SETTING: Ein-Tal Eye Center, Tel-Aviv, Israel. DESIGN: Retrospective case series. METHODS: Eyes having cataract extraction surgery with steep and flat preoperative corneal curvatures determined with the Lenstar-LS900 device were enrolled. Refractive prediction errors for the Barrett Universal II, Haigis, Hill-RBF, Hoffer-Q, Holladay 1, Holladay 2, Olsen, and SRK/T formulas were compared...
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28991349/surgical-outcome-of-congenital-cataract-in-eyes-with-microcornea
#17
Jyoti Matalia, Sheetal Shirke, K Bhujang Shetty, Himanshu Matalia
PURPOSE: To report the intraoperative and postoperative outcomes of congenital cataract surgery in eyes with microcornea. METHODS: In this retrospective, interventional, comparative case series, the authors reviewed 47 eyes of 26 children with microcornea and congenital cataract (21 bilateral and 5 unilateral) who underwent lens aspiration with primary posterior capsulectomy and anterior vitrectomy between 2008 and 2014 with a minimum follow-up period of 6 months...
October 9, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28991340/comparison-of-corneal-endothelial-cell-loss-between-two-femtosecond-laser-platforms-and-standard-phacoemulsification
#18
Zaina Al-Mohtaseb, Xu He, Nilufer Yesilirmak, Daniel Waren, Kendall E Donaldson
PURPOSE: To analyze and compare the changes in endothelial cell density (ECD) and cumulative dissipated energy (CDE) in patients having cataract surgery with two different femtosecond laser platforms and standard phacoemulsification. METHODS: This prospective non-randomized comparative study included patients scheduled to undergo cataract extraction using femtosecond laser-assisted cataract surgery (FLACS) (60 eyes) or standard phacoemulsification (60 eyes) between September 2013 and March 2016...
October 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28991338/age-related-changes-in-corneal-astigmatism
#19
Xu Shao, Kai-Jing Zhou, An-Peng Pan, Xue-Ying Cheng, He-Xie Cai, Jin-Hai Huang, A-Yong Yu
PURPOSE: To analyze the changes in corneal astigmatism as a function of age and develop a novel model to estimate corneal astigmatic change according to age. METHODS: This was a cross-sectional study of right eyes of 3,769 individuals. Total corneal astigmatism, keratometric astigmatism, anterior corneal astigmatism, and posterior corneal astigmatism were measured by a Scheimpflug tomographer. Smoothing fitting curves of polar values of corneal astigmatism as a function of age were drawn and average changes in corneal astigmatism at different ages were calculated...
October 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28991337/accuracy-of-a-new-swept-source-optical-coherence-tomography-biometer-for-iol-power-calculation-and-comparison-to-iolmaster
#20
Giacomo Savini, Kenneth J Hoffer, H John Shammas, Jaime Aramberri, Jinhai Huang, Piero Barboni
PURPOSE: To investigate the accuracy of the measurements provided by a new optical biometer (OA-2000, Tomey Corporation, Nagoya, Japan) for calculating the intraocular lens (IOL) power and to compare the refractive outcomes to those obtained with the IOLMaster 500 (Carl Zeiss Meditec, Jena, Germany). METHODS: In this interventional multicenter study, consecutive patients having cataract surgery were enrolled. Only the IOL model used in the largest sample of patients was selected and the eyes implanted with that IOL were subsequently analyzed...
October 1, 2017: Journal of Refractive Surgery
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