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Corneal surgery

Ayhan Saglik, Hakim Celik
PURPOSE: To compare the accuracy of the anterior corneal simulated keratometry (SimK) and the Holladay equivalent keratometry reading (EKR) provided by a Scheimpflug camera (Pentacam HR) with the keratometry (K) provided by a Placido system (T-Cone topography) in keratoconus and control eyes. METHODS: This prospective study included 40 consecutive patients with keratoconus and 40 voluntary participants with no ocular complaints. Any patients with corneal scar, corneal trauma, history of corneal surgery or contact lens usage were excluded from the study...
June 22, 2018: International Ophthalmology
Yichen Wang, Priyha Mahesh, Yan Wang, Samuel G Novo, Mahbubul H Shihan, Brielle Hayward-Piatkovskyi, Melinda K Duncan
The appropriate spatial and temporal regulation of canonical Wnt signaling is vital for eye development. However, the literature often conflicts on the distribution of canonical Wnt signaling in the eye. Here, using a sensitive mouse transgenic reporter line, we report a detailed re-evaluation of the spatiotemporal dynamics of canonical Wnt signaling in the developing eye. Canonical Wnt activity was dynamic in the optic vesicle and later in the retina, while it was absent from the ectodermal precursors of the lens and corneal epithelium...
June 19, 2018: Experimental Eye Research
Yang Liu, YingNan Zhang, Qingfeng Liang, Chao Yan, Li Wang, Jing Zhang, ZhiQiang Pan
BACKGROUND: In current non-human primate models, full-thickness porcine grafts could not achieve long-term survival without using potent systemic immunosuppressors. Moreover, the thickness disparity in xeno-PKP proved to be hard to manipulate and may cause several complications which also could prevent the grafts from long survival. Considering the advantages of Descemet's stripping automated endothelial keratoplasty (DSAEK) derived from its ultrathin graft and lower rejection rate, we hypothesize xeno-DSAEK may overcome these imperfections in xeno-PKP...
June 22, 2018: Xenotransplantation
Jonathan Aboshiha, Mark N A Jones, Cathy L Hopkinson, Daniel F P Larkin
Importance: An increasing proportion of corneal transplant procedures are undertaken for replacement of a failed previous graft. The proportion of lamellar transplant procedures has significantly increased. There are limited large-scale reports on regraft procedures that may help guide surgeons and patients in their choice of surgery. Objective: To examine the corneal transplant replacement survival rates for the 3 main indications and types of regraft surgery. Design, Setting, and Participants: This national transplant registry study examined surgery and follow-up data on all corneal transplants performed in the United Kingdom from April 1, 1999, through March 31, 2016...
June 21, 2018: JAMA Ophthalmology
Piyush Kohli, Sudesh Kumar Arya, Amit Raj, Uma Handa
AIM: To evaluate the signs and symptoms of dry eye after phacoemulsification; effects on the status of ocular surface using impression cytology; and associated risk factors. METHODS: Prospective study included 50 eyes (50 patients) with no dry eye signs or symptoms, who underwent clear corneal phacoemulsification for senile cataract. Dry eye indices used included Ocular Surface Disease Index scoring, Schirmer I test, tear break up time, tear meniscus height, corneal fluorescein staining, lissamine green staining and goblet cell density (GCD) with the help of impression cytology...
June 20, 2018: International Ophthalmology
Sotaro Mori, Mari Sakamoto, Takuji Kurimoto, Akiyasu Kanamori, Kaori Ueda, Yukako Inoue, Yuko Yamada, Makoto Nakamura
PURPOSE: The purpose of this study was to evaluate the surgical success of sulcus fixation of Baerveldt glaucoma implant (BGIs) in special reference to corneal damage. METHODS: This observational prospective cohort study included 24 patients who underwent a median of 3.0 previous intraocular surgeries and sulcus fixation of BGIs for the first time. The intraocular pressure (IOP), the number of ocular hypotensives used, corneal endothelial cell density (ECD), and logMAR-converted best-corrected visual acuity (VA) of each patient were measured preoperatively and postoperatively until 12 months after surgery...
June 20, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Catherine P Creuzot-Garcher, Anne Sophie Mariet, Eric Benzenine, Vincent Daien, Jean-François Korobelnik, Alain M Bron, Catherine Quantin
PURPOSE: To assess the incidence of acute postoperative endophthalmitis (POE) after cataract surgery combined with corneal, glaucoma or vitreoretinal surgical procedures from 2005 to 2014 in France. METHODS: In this cohort study, acute POE occurring within 6 weeks after surgery was identified by means of billing codes recorded in a national database in patients operated for cataract extraction with phacoemulsification, or corneal, glaucoma or vitreoretinal surgical procedures, either combined or stand-alone...
June 20, 2018: British Journal of Ophthalmology
Nicolas Cesário Pereira, Evandro Ribeiro Diniz, Ramon Coral Ghanem, Ruy Cunha Filho, Tatiana Moura Prazeres, Walton Nose, Adriana Dos Santos Forseto
PURPOSE: This report describes the use of Descemet membrane endothelial keratoplasty for the management of endothelial decompensation after multifocal intraocular lens implantation. METHODS: In this retrospective study, we reviewed and assessed the surgical outcomes of 9 patients (9 eyes) who underwent Descemet membrane endothelial keratoplasty after multifocal intraocular lens implantation. RESULTS: Corneal edema occurred due to Fuchs endothelial corneal dystrophy (n=3), pseudophakic bullous keratopathy (n=3), Descemet's membrane detachment (n=2), and toxic anterior segment syndrome (n=1)...
June 2018: Arquivos Brasileiros de Oftalmologia
Francisco Bandeira, Merce Morral, Daniel Elies, Sergio Eguiza, Spyridoula Souki, Felicidad Manero, Jose L Güell
Synopsis: Transitional toric intraocular lens (IOL) was developed to improve refractive outcomes in cataract surgery. We report refractive, vectorial outcomes, and stability of spherical equivalent over 12 months after implantation of this IOL. Purpose: To evaluate visual and refractive outcomes of a transitional conic toric intraocular lens (IOL) (Precizon® ) for the correction of corneal astigmatism in patients undergoing cataract surgery. Setting: The Ocular Microsurgery Institute (IMO), a private practice in Barcelona, Spain...
2018: Clinical Ophthalmology
Mark A P Fajgenbaum, Nick Kopsachilis, Emma J Hollick
PURPOSE: To report surgical outcomes and endothelial cell density (ECD) trends up to 2 years post-operatively in the first cohort of eyes undergoing Descemet's membrane endothelial keratoplasty (DMEK) for low-to-moderate risk indications at our UK centre. Tight corneal sutures were used to ensure high intraoperative pressure from intracameral air for 10-min and to maintain a good post-operative air fill. Outcomes were compared to a prior series at our unit of similar eyes having Descemet's stripping endothelial keratoplasty (DSEK)...
June 19, 2018: Eye
Alfonso Vasquez-Perez, Francesco Matarazzo, Niraj Mandal, Stephen Tuft
PURPOSE: To describe a case of acute glaucoma after cyanoacrylate gluing for a non-traumatic central corneal perforation. METHODS: A 55-year-old woman with history of rheumatoid arthritis and severe dry eye presented to emergency with a right central corneal perforation. She was treated successfully with the use cyanoacrylate glue patch but iridocorneal adhesions remained. The next day she presented with ocular pain, headaches and vomiting. On examination she had shallow anterior chamber with no aqueous leakage but her intraocular pressure was 56▒mm Hg measured with rebound tonometry...
June 18, 2018: Journal of Glaucoma
A Chiche, L Trinh, C Baudouin, A Denoyer
Refractive surgery is a field in constant evolution. In recent years, a new procedure has appeared under the name SMILE (SMall Incision Lenticule Extraction). This technique, carried out solely with a femtosecond laser, should make it possible to better preserve corneal innervation and biomechanics. After a detailed review of the technique itself, we then focus on the scientific evidence for the safety and efficacy of SMILE and its current indications. Advantages of SMILE will be discussed in comparison to the conventional techniques, particularly concerning dry eye and the risk of corneal ectasia related to LASIK...
June 15, 2018: Journal Français D'ophtalmologie
Ivey L Thornton, Brian K McMains, Michael E Snyder
PURPOSE: To report the safety and efficacy of single-port pars plana anterior vitrectomy. SETTING: Cincinnati Eye Institute, Cincinnati, Ohio, USA. DESIGN: Retrospective case series. METHODS: Eyes that had anterior vitrectomy from September 2010 to June 2016 were electronically identified. Charts were reviewed for demographics, history of ocular trauma, underlying ocular or systemic comorbidity, surgical indications, outcomes, and postoperative complications...
June 13, 2018: Journal of Cataract and Refractive Surgery
Loizos C Siakallis, Jimmy M Uddin, Katherine A Miszkiel
INTRODUCTION: Thyroid eye disease (TED), is a term referring to the extrathyroidal manifestation of Grave's disease, a disorder which is currently the most common cause of hyperthyroidism and is characterised by underlying autoimmunity.The pathogenic course of the disease can be broadly classified into two stages, an early inflammatory and a late fibrotic stage. These stages are reflected in clinical severity and activity classifications, such as Clinical Activity Score and Class 0: No signs or symptoms, 1: Only signs, no symptoms (e...
June 13, 2018: Ophthalmic Plastic and Reconstructive Surgery
Yibing Zhang, Yuan Hu, Xiaodong Li, Xiaoru Shi, Feihong Xu, Hui Jia
The aim of the present study was to investigate the role of the limbal stem cells in corneal epithelial homeostasis in patients with peripheral corneal disease who received corneal transplantation surgery. This retrospective study enrolled 85 patients (85 eyes) with peripheral corneal lesion who underwent corneal transplantation at Department of Ophthalmology in First Hospital of Jilin University, Jilin, China. All patients during each follow-up period were examined for best corrected visual acuity, corneal reconstruction (assessed by slit-lamp biomicroscopy), anterior segment optical coherence tomography, and confocal microscopy...
June 2018: Experimental and Therapeutic Medicine
Tao Guo, Peng Gao, Li Fang, Li Guo, Yuchen Fan, Changgen Liu
The present prospective clinical observational study aimed to evaluate the efficacy of Toric intraocular lenses (IOL) to achieve rotational stability and astigmatism correction in eyes with high myopia. A total of 27 consecutive cataract patients (39 eyes) with pre-existing corneal astigmatism (1.5-3.5 D) were divided into two groups according to their refractive status: One group of 18 eyes with high myopia -(12.5-6.0 D) and another group consisting of 21 eyes with emmetropia or low myopia (-3.0-0.0 D). All eyes underwent cataract phacoemulsification surgeries by the same surgeon, with the implantation of an AcrySof® Toric IOL at the pre-designed degree...
June 2018: Experimental and Therapeutic Medicine
Gian Marco Tosi, Tommaso Bacci, Antonio Tarantello, Gianluca Martone, Claudio Traversi, Davide Marigliani, Gabriele Cevenini, Gianni Virgili
PURPOSE: To assess corneal subbasal nerve density (SBND) and corneal sensitivity (CS) after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) without intraoperative 360-degree laser treatment using contact or noncontact panoramic viewing systems. METHODS: This is a prospective study of 34 eyes affected by RRD, which underwent PPV using contact (18 eyes) and noncontact (16 eyes) panoramic viewing systems; 12 eyes which underwent scleral buckling, and 17 eyes which underwent cataract surgery...
June 7, 2018: Cornea
Sayan Basu, Ritu Nagpal, Juan Carlos Serna-Ojeda, Swapnil Bhalekar, Bhupesh Bagga, Virender Sangwan
PURPOSE: To describe the anatomical and functional outcomes of the novel LVP keratoprosthesis (Kpro), developed as an alternative to the modified osteo-odonto keratoprosthesis (MOOKP), in eyes with end-stage corneal blindness where conventional corneal surgeries are contraindicated. METHODS: This prospective case series included 58 eyes of 56 patients (12 children and 44 adults) with severe bilateral keratopathy and completely dry, dermalised ocular surfaces who underwent unilateral LVP Kpro implantation from 2012 to 2016...
June 11, 2018: British Journal of Ophthalmology
Alfredo Amigó, Paula Martinez-Sorribes, Margarita Recuerda
We present a series of 5 consecutive cases in which a small-aperture corneal inlay (Kamra ACI7000PDT) was uneventfully implanted in a corneal pocket created at a depth between 200 μm and 250 μm. Three months after surgery, all patients had good visual results, normal corneal surfaces, and adequate stromal healing. Between 6 months and 19 months after surgery, visually significant refractive changes appeared in the form of a hyperopic shift in 4 cases and a myopic shift in 1 case. Topical steroids were ineffective...
May 2018: Journal of Cataract and Refractive Surgery
Kendall Donaldson, Luis Fernández-Vega-Cueto, Richard Davidson, Deepinder Dhaliwal, Rex Hamilton, Mitchell Jackson, Larry Patterson, Karl Stonecipher
As cataract surgery has evolved into lens-based refractive surgery, expectations for refractive outcomes continue to increase. During the past decade, advancements in technology have provided new ways to measure the cornea in preparation for cataract surgery. The increasing ability to accurately estimate corneal power allows determination of the most precise intraocular lens (IOL) for each patient. New equipment measures the anterior and posterior corneal surfaces to most accurately estimate corneal power and corneal aberrations...
May 2018: Journal of Cataract and Refractive Surgery
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