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https://www.readbyqxmd.com/read/28628490/comparison-of-efficacy-of-difluprednate-0-05-and-loteprednol-gel-0-5-after-cataract-surgery
#1
Bryan Abessi, Lauren Brooksby, Robert L Schultze
PURPOSE: To compare the outcomes and complications of topical difluprednate 0.05% and loteprednol gel 0.5% after routine cataract surgery. METHODS: Subjects received either difluprednate emulsion 0.05% (n=30 eyes) or loteprednol gel 0.5% (n=30 eyes) after routine cataract surgery. Topical steroid drops were initiated 3 days before cataract surgery and continued for 2 weeks postoperatively. Anterior chamber (AC) cell grade, corneal edema, corneal pachymetry, visual acuity, ocular surface quality (Oxford scale), and intraocular pressure (IOP) were evaluated at 1 day, 1 week, and 1 month postoperatively...
June 16, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28626416/multiquadrant-subtenon-triamcinolone-injection-for-acute-corneal-graft-rejection-a-case-report
#2
Sunali Goyal, Sami H Uwaydat
BACKGROUND: We report a case of reversal of an acute corneal graft rejection following multiquadrant subtenon triamcinolone injection. CASE PRESENTATION: A 19-year-old woman who had acute corneal graft rejection failed to show resolution of the graft rejection after standard treatment with systemic, intravenous, and topical steroids. The graft rejection, however, responded to injection of triamcinolone in multiple subtenon quadrants. CONCLUSIONS: For corneal graft rejection, multiquadrant subtenon triamcinolone injections may be a safe adjunct to systemic treatment...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28617448/diminishing-effectiveness-of-long-term-maintenance-topical-steroid-therapy-in-ppi-non-responsive-eosinophilic-esophagitis
#3
Swathi Eluri, Thomas M Runge, Jason Hansen, Bharati Kochar, Craig C Reed, Benjamin S Robey, John T Woosley, Nicholas J Shaheen, Evan S Dellon
OBJECTIVES: While topical corticosteroids are first-line therapy for eosinophilic esophagitis (EoE), the data regarding long-term effectiveness are lacking. We aimed to determine long-term histologic and endoscopic outcomes of maintenance therapy in EoE steroid responders. METHODS: We performed a retrospective study of adults with EoE at UNC Hospitals who had initial histologic response (<15 eos/hpf) after 8 weeks of topical steroids, and maintained on therapy...
June 15, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/28615961/the-role-of-novel-biomarkers-in-childhood-idiopathic-nephrotic-syndrome-a-narrative-review-of-published-evidence
#4
REVIEW
Samuel N Uwaezuoke
Two histological subtypes of idiopathic nephrotic syndrome are commonly recognized in children, namely minimal change nephropathy and focal segmental glomerulosclerosis. Children with minimal change nephropathy (the majority of whom are steroid-sensitive) and focal segmental glomerulosclerosis (the majority of whom are steroid-resistant) require early identification in order to ensure appropriate therapeutic intervention and better outcome. Although renal biopsy and histology remain the ideal diagnostic steps to identify these histological subtypes, reports indicate that serum and urinary biomarkers are now being utilized in the investigation of childhood idiopathic nephrotic syndrome...
2017: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/28611969/anastomotic-strictures-after-esophageal-atresia-repair-incidence-investigations-and-management-including-treatment-of-refractory-and-recurrent-strictures
#5
REVIEW
Renato Tambucci, Giulia Angelino, Paola De Angelis, Filippo Torroni, Tamara Caldaro, Valerio Balassone, Anna Chiara Contini, Erminia Romeo, Francesca Rea, Simona Faraci, Giovanni Federici di Abriola, Luigi Dall'Oglio
Improved surgical techniques, as well as preoperative and postoperative care, have dramatically changed survival of children with esophageal atresia (EA) over the last decades. Nowadays, we are increasingly seeing EA patients experiencing significant short- and long-term gastrointestinal morbidities. Anastomotic stricture (AS) is the most common complication following operative repair. An esophageal stricture is defined as an intrinsic luminal narrowing in a clinically symptomatic patient, but no symptoms are sensitive or specific enough to diagnose an AS...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28611647/pediatric-bilateral-blue-laser-pointer-induced-maculopathy
#6
Joseph Raevis, Eric Shrier
BACKGROUND: We report the first case of pediatric bilateral blue laser pointer maculopathy with complete resolution of visual symptoms. CASE: A 12-year-old boy presented with bilateral decreased visual acuity and central scotomata after blue laser pointer exposure. He was treated with a Medrol Dosepak and topical nonsteroidal anti-inflammatory drug (NSAID), with gradual visual acuity improved from 20/40 OU to 20/20 OU over 22 weeks, but with persistent evidence of outer retinal layer disruption from the external limiting membrane to the interdigitation zone...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28608048/six-food-elimination-diet-and-topical-steroids-are-effective-for-eosinophilic-esophagitis-a-meta-regression
#7
Cary C Cotton, Swathi Eluri, W Asher Wolf, Evan S Dellon
BACKGROUND: Topical corticosteroids or six-food elimination diet is recommended as initial therapy for eosinophilic esophagitis (EoE). AIMS: We aimed to summarize published manuscripts that report outcomes of these therapies for EoE. METHODS: We performed a systematic review in MEDLINE, Web of Science, and Embase of published manuscripts describing topical fluticasone, topical budesonide, and six-food elimination diet as therapies for EoE...
June 12, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28598005/higher-concentrations-of-dithranol-appear-to-induce-hair-growth-even-in-severe-alopecia-areata
#8
M R Ngwanya, N A Gray, F Gumedze, A Ndyenga, N P Khumalo
Alopecia areata (AA) is the commonest autoimmune cause of non-scarring alopecia. Topical treatments including corticosteroids and irritants maybe beneficial. Studies report variable hair regrowth with dithranol (anthralin) but all used low concentrations (0.1-1.25%) and inconsistent measurements of AA severity. We report retrospective data (2005-2014) of 102 patients who had failed ultra-potent topical steroids and were referred to a specialist hair clinic for treatment with dithranol up to 3%. The severity of alopecia areata tool was used and participants graded as mild (<25%), moderate (>25 to 75%), and severe (>75%) hair loss...
June 9, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28597020/pemphigus-vulgaris-persistently-localized-to-the-nose-with-local-and-systemic-response-to-topical-steroids
#9
Connie Zhang, Ilana Goldscheider, Thomas Ruzicka, Miklós Sárdy
No abstract text is available yet for this article.
June 9, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28588813/severe-dermatitis-might-be-caused-by-a-cross-reaction-between-nickel-and-palladium-and-dental-amalgam-resolved-following-removal-of-dental-restorations
#10
Yoshiro Fujii
This report demonstrates a case of atopic dermatitis that was unresponsive to topical steroid therapy. This clinical report highlights the fact that metals used in dental treatment, such as mercury, as well as cross-reactions between nickel and palladium, may cause systemic hypersensitivity or toxicity.
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28587382/effect-of-vbc-1814-7j-a-poly-phytocompound-on-a-non-infectious-model-of-pharyngitis
#11
Junji Uemura, Ravinder Nagpal, Nicola Zerbinati, Birbal Singh, Massimiliano Marcellino, Dheeraj Mohania, Francesco Marotta, Fang He, Antonio Ayala, Yasuhiro Kasugai, Roberto Catanzaro
Pharyngitis presents as an inflammation of the oropharynx, and clinical examination often shows evidence of nasopharyngitis. In numerous cases the condition occurs as a self-limiting illness of non-infectious aetiology, whose clinical management remains a matter for debate given the inappropriateness of antibiotics, the reported worsening following steroid use and the recent discouragement of the use of Chinese herbal medicine. The aim of the present study was thus to test VBC-1814/7J, a poly-phytocompound with known anti-inflammatory and immune-response enhancing properties, in an experimental model of non-infectious pharyngitis...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28586504/removal-of-persistent-cellular-deposits-after-foldable-iris-fixated-phakic-iol-implantation
#12
Marilia Lordello Passos, Ramon Coral Ghanem, Vinícius Coral Ghanem
PURPOSE: To report a case of severe recurrent cellular deposits after Artiflex intraocular lens (Ophtec B. V., Groningen, The Netherlands) implantation. METHODS: Case report. RESULTS: A 25-year-old woman underwent uneventful Artiflex intraocular lens implantation in both eyes. After 3 months, severe cellular deposits were seen in the posterior surface of the lens in one eye. Topical steroids were administered, with temporary improvement. Four months later, the deposits recurred and did not respond to topical steroids...
June 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28584755/misuse-of-topical-corticosteroids-over-face-a-clinical-study
#13
Kajal Manchanda, Sandip Mohanty, Pallavi C Rohatgi
INTRODUCTION: Topical corticosteroids (TCS) have been widely used in various dermatological diseases. However, because of inadvertent use, TCS misuse has become a common problem faced by dermatologists in various parts of the world. Prolonged use over the face can cause various side effects such as steroid rosacea, acneiform eruptions, and hypertrichosis. AIM: To study the effects of TCS misuse and analyze various factors promoting its use on face. MATERIALS AND METHODS: A total of 100 patients presenting with various facial dermatoses following the misuse of TCS on the face were studied...
May 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28584222/paederus-dermatitis
#14
REVIEW
Kaliaperumal Karthikeyan, Annapurna Kumar
Paederus dermatitis is an irritant dermatitis caused by pederin, a toxin produced by the rove beetle (Paederus). The disease occurs worldwide, but it is often not recognized as a history of contact with the insect is frequently absent. It is commonly seen in the rainy season. Crushing the insect releases pederin, resulting in the characteristic linear lesions with a burning sensation that heal with hyperpigmentation. Treatment comprises immediate washing of the area to eliminate the toxin and topical application of a topical steroid-antibiotic combination...
July 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/28574002/management-of-a-rare-presentation-of-vogt-koyanagi-harada-disease-in-human-immunodeficiency-virus-acquired-immunodeficiency-disease-syndrome-patient
#15
D Priya, S Sudharshan, Jyotirmay Biswas
Vogt-Koyanagi-Harada (VKH), a multisystem autoimmune bilateral panuveitis with systemic manifestations, is uncommon in immunocompromised patients such as human immunodeficiency virus (HIV)/acquired immunodeficiency disease syndrome (AIDS). We report a rare presentation of VKH in a 45-year-old HIV-positive female on highly active antiretroviral therapy (HAART) who presented with a history of recurrent panuveitis. A diagnosis of probable VKH was made based on ocular and systemic signs and symptoms. She was treated with topical and systemic steroids with close monitoring of CD4 counts and viral loads...
May 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28573998/corneal-ulcer-due-to-a-rare-pleosporalean-member-of-the-genus-bipolaris-following-cow-tail-injury-to-the-eye-a-case-report-and-review-of-literature
#16
H Vijaya Pai, Esha Jamal, Prakash Peralam Yegneswaran
Aspergillus and Fusarium are the most common fungi causing mycotic keratitis. Injury to the eye with vegetable matter, cow tail injury, long-term use of topical steroids are some of the risk factors for mycotic keratitis. There are few case reports of keratitis caused by Bipolaris. The human pathogenic species in the genus are Bipolaris spicifera, Bipolaris hawaiiensis, Bipolaris papendorfii, and Bipolaris australiensis. Most commonly reported keratitis is caused by B. hawaiiensis, followed by B. spicifera...
May 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28571255/effect-of-diclofenac-mouthwash-on-postoperative-pain-after-periodontal-surgery
#17
Ashank Mishra, Jyotsna Amalakara, Haritha Avula, Krishnajaneya Reddy
INTRODUCTION: Non-Steroidal AntiInflammatory Drugs (NSAIDs) are widely used drugs for the management of pain. Oral administration of NSAIDs has various adverse events like gastrointestinal alterations - nausea, dyspepsia and gastrointestinal bleeding, hepatotoxicity and blood dyscrasias. As orally given NSAIDs are associated with systemic side effects, it is preferred to alleviate pain and inflammation using topical medication. Thus, recently the focus has been on the development of topical administration of NSAIDs in the form of gels, toothpastes and rinses...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28571174/comparison-of-steroid-and-itraconazole-for-prevention-of-recurrence-in-allergic-fungal-rhinosinusitis-a-randomized-controlled-trial
#18
Moirangthem Rojita, Swagatika Samal, Pradeep Pradhan, V P Venkatachalam
INTRODUCTION: Allergic Fungal Rhinosinusitis (AFRS) is due to the continuous exposure of fungal antigens to an atopic individual. Medical treatment following the surgery is the standard protocol often practiced for the treatment of AFRS. Steroid (systemic/topical) has been considered as the standard medical treatment for the control of the disease in AFRS although most of the patients show recurrence with long term follow up. Instead, antifungals (itraconazole) can be tried to decrease the recurrence rate which acts by inhibiting the fungal growth in the postoperative period...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28566911/intense-pulsed-light-and-q-switched-1-064-nm-neodymium-doped-yttrium-aluminum-garnet-laser-treatment-for-the-scarring-lesion-of-discoid-lupus-erythematosus
#19
Yun Sun Byun, Jee Hee Son, Yong Se Cho, Bo Young Chung, Hee Jin Cho, Chun Wook Park, Hye One Kim
Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus that can cause permanent scarring. Treatment of DLE includes protection from sunlight and artificial sources of ultraviolet light, as well as systemic and topical medications. The first-line standard therapies are antimalarials and topical steroids. Other systemic therapies include systemic steroid, azathioprine, dapsone, and immunosuppressive agents. Topical tacrolimus and pimecrolimus have also been evaluated. Recent studies reported that several treatments, including pulsed dye laser, CO2 laser, intense pulsed light (IPL), and 1,064-nm long-pulse neodymium-doped yttrium aluminum (Nd:YAG) have been used for the cosmetic treatment of DLE...
June 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28562545/sumatriptan-induced-angle-closure-glaucoma-a-case-report
#20
Cherng-Ru Hsu, Yi-Hao Chen, Ming-Cheng Tai, Da-Wen Lu
RATIONALE: Drug-induced bilateral angle-closure glaucoma is a rare event and should be treated correctly and promptly to prevent visual loss. PATIENT CONCERNS: We report a rare case of sumatriptan-induced bilateral angle-closure glaucoma in a young woman with migraine, and explore the possible mechanism. DIAGNOSES: We describe the clinical outcome of a patient with sumatriptan-induced bilateral angle-closure glaucoma. The patient presented with bilateral acute elevation of intraocular pressure (IOP) and myopic shift...
June 2017: Medicine (Baltimore)
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