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hemostasis and surgery

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https://www.readbyqxmd.com/read/29453623/a-novel-suction-coagulation-integrated-probe-for-achieving-better-hemostasis-development-and-clinical-use
#1
Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Hirofumi Yamamoto, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki, Kiyokazu Nakajima
PURPOSES: Modern electrosurgical tools have a specific coagulation mode called "soft coagulation". However, soft coagulation has not been widely accepted for surgical operations. To optimize the soft coagulation environment, we developed a novel suction device integrated with an electrosurgical probe, called the "Suction ball coagulator" (SBC). In this study, we aimed to optimize the SBC design with a prototyping process involving a bench test and preclinical study; then, we aimed to demonstrate the feasibility, safety, and potential effectiveness of the SBC for laparoscopic surgery in clinical settings...
February 17, 2018: Surgery Today
https://www.readbyqxmd.com/read/29452284/-micro-endoscopic-vs-pure-endoscopic-surgery-for-spinal-intra-dural-mass-lesions-a-comparative-study-and-review
#2
Sivashanmugam Dhandapani, Madhivanan Karthigeyan
BACKGROUND: Endoscopy is increasingly being used for minimal invasiveness and panoramic visualization, with unclear efficacy and safety among spinal intradural lesions. OBJECTIVE: To compare micro-endoscopic and pure-endoscopic surgery for spinal intradural lesions. METHODS: Spinal intradural lesions operated by us using endoscopic/access ports were categorized 'micro-endoscopic' (predominant microscope use), or 'pure-endoscopic' (standalone endoscopy) surgery, and studied with respect to clinico-radiological features, techniques, peri-operative course, histopathology, clinical and radiological outcome at minimum of 3 months...
February 13, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29442539/platelets-in-wound-healing-and-regenerative-medicine
#3
Julia Etulain
Although platelets are widely recognized as having a critical role in primary hemostasis and thrombosis, increasing experimental and clinical evidence identifies these enucleated cells as relevant modulators of other physiopathological processes including inflammation and tissue regeneration. These phenomena are mediated through the release of growth factors, cytokines, and extracellular matrix modulators that sequentially promote (i) revascularization of damaged tissue through the induction of migration, proliferation, differentiation, and stabilization of endothelial cells in new blood vessels; (ii) restoration of damaged connective tissue through migration, proliferation, and activation of fibroblasts; and (iii) proliferation and differentiation of mesenchymal stem cells into tissue-specific cell types...
February 14, 2018: Platelets
https://www.readbyqxmd.com/read/29438459/dietary-supplements-with-antiplatelet-activity-a-solution-for-everyone
#4
Beata Olas
Dietary supplements can have beneficial effects on a number of risk factors for cardiovascular diseases, and interest in the use of nonpharmacologic nutraceutical-based treatments for cardiovascular disorders is growing. The aim of this review is to present the role of dietary supplements with antiplatelet activity in the prophylaxis and treatment of cardiovascular disorders. In addition, this paper describes their effects on another very important element of hemostasis-blood coagulation. However, because controlled human clinical experiments are too limited to clearly identify the antiplatelet and anticoagulant properties of dietary supplements, used alone or in combination with classical antiplatelet therapy (e...
January 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29429776/interventional-treatment-experience-in-multiple-injury-with-major-abdominal-or-pelvic-injuries-160-cases-analysis
#5
Tian-Xi Zhang, Mei Han, Peng Ye, Quan Hu, Jia-Lin Li, Ling Yin, An-Yong Yu
PURPOSE: To observe the therapeutic effect of interventional embolization and haemorrhage control in multiple trauma patients with a major abdominal or pelvic injury. METHODS: Data of 160 multiple trauma patients with a major abdominal or pelvic injury were retrospectively analyzed. They were admitted into the Department of Emergency of the First Affiliated Hospital of Zunyi Medical College from October 2013 to April 2016. Eighty-seven patients who received emergent intervention for embolization and haemorrhage control were set as group A, including 72 males and 15 females, with an average age of (39...
January 31, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29427752/diagnosis-and-treatment-efficacy-of-digital-subtraction-angiography-and-transcatheter-arterial-embolization-in-post-pancreatectomy-hemorrhage-a-single-center-retrospective-cohort-study
#6
Yuan Fang, Xu Han, Lingxiao Liu, Wenhui Lou
BACKGROUND: To evaluate the diagnostic and treatment efficacy of digital subtraction angiography (DSA), transcatheter arterial embolization (TAE) in post-pancreatectomy hemorrhage (PPH). MATERIALS AND METHODS: This is a single-center retrospective cohort study. Clinicopathological data of 23 patients with PPH from August 2009 to November 2016 were collected. We observed (1) DSA procedures and hemorrhagic sites (2) TAE: successful rate and complications (3) Follow-up...
February 7, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29416788/improved-anti-tumor-efficacy-via-combination-of-oxaliplatin-and-fibrin-glue-in-colorectal-cancer
#7
Yuzhu Hu, Ting Yu, Xiaoxiao Liu, Yihong He, Lihong Deng, Jiajuan Guo, Yuanqi Hua, Ting Luo, Xiang Gao
Colorectal cancer is very common worldwide and advanced colorectal cancer exhibited very poor clinical outcome. Oxaliplatin (OXP) is one of the principal chemotherapeutic agents in colorectal cancer treatment presenting impressive anti-tumor ability, limited by adverse effect in clinical practice. Fibrin glue (FG) is a biocompatible formulation made of fibrinogen and thrombin, extensively used in surgery for hemostasis, tissue adhesion and sealing. In this study, FG was innovatively applied as OXP delivery system and results showed enhanced anti-tumor performance in subcutaneous model and abdominal metastasis model of murine colorectal cancer compared with that of OXP used alone...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29411561/a-case-of-intraoperative-anaphylaxis-caused-by-bovine-derived-thrombin
#8
Hye Jung Park, Kyung Soo Suk, Jung Won Park
Intraoperative bovine-derived topical thrombin is still widely used for hemostasis during surgery. A 38-year-old woman with chronic spontaneous urticaria was referred to the orthopedic surgery department for herniated disk and myelopathy. During the first stage of operation, bovine-derived thrombin powder soaked in Gelfoam was used as a hemostatic aid. After 30 minutes, the patient developed anaphylactic shock with systemic skin rash and angioedema. Repeated intravenous bolus and infusion of vasopressor were carried out, and her blood pressure normalized...
March 2018: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/29403324/pharmacokinetics-based-clinical-management-of-acquired-von-willebrand-syndrome-a-case-report
#9
Candice M Baldeo, Candido E Rivera, Han W Tun, Prakash Vishnu
von Willebrand disease (VWD) is a common bleeding disorder caused by defective or low levels of von Willebrand factor (VWF). Although most cases of VWD are caused by genetic mutations, some are acquired due to various disease states. In managing VWD, the aim is to normalize plasma levels of both VWF and factor VIII (FVIII), as this aids in hemostasis. Desmopressin usually corrects VWF level in type 1 VWD by inducing the release of endogenous VWF. In cases where desmopressin is ineffective or cannot be used, transfusion of virally inactivated, plasma-derived VWF/FVIII concentrate or infusion of recombinant VWF (Vonvendi) is indicated...
2018: Journal of Blood Medicine
https://www.readbyqxmd.com/read/29402157/alternative-approaches-to-surgical-hemostasis-in-patients-with-morbidly-adherent-placenta-undergoing-fertility-sparing-surgery
#10
Roman G Shmakov, Aleksandr A Vinitskiy, Vladimir D Chuprinin, Ekaterina L Yarotskaya, Gennady T Sukhikh
AIM: To evaluate the efficacy of different methods of surgical hemostasis, including the ligation of internal iliac arteries (IIA), temporary occlusion of the common iliac artery (CIA) and combined compression hemostasis, during cesarean section in patients with morbidly adherent placenta (MAP). MATERIALS AND METHODS: The study included 54 patients with MAP. All patients underwent cesarean section with application of surgical hemostasis techniques. In Group 1 (n = 15), ligation of IIA was performed, in Group 2 (n = 18) extravasal temporary occlusion of CIA, and in Group 3 (n = 21) combined compression hemostasis was applied...
February 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29394560/-a-case-of-infectious-pseudoaneurysm-that-developed-after-surgery-for-local-recurrence-of-rectal-cancer
#11
Motonari Ohashi, Masahiro Iwama, Shojirokazunori Ikenaga, Makoto Yokoyama
In February 2011, a male patient in his 60's underwent a low anterior resection and lateral lymph node dissection for lower rectal cancer. Due to large intestinal obstruction from local recurrence, an abdominoperineal resection was performed 5 years 8 months after his first surgery. Inflammation of the pelvic dead space persisted, requiring drainage after the surgery. Although bloody discharge was observed on the 12th and 30th postoperative day, the source of bleeding was not identified on contrast-enhanced CT...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29383310/total-endoscopic-approach-in-glomus-tympanicum-surgery
#12
Ahmad Daneshi, Alimohamad Asghari, Saleh Mohebbi, Mohammad Farhadi, Farhad Farahani, Mohammad Mohseni
Introduction: Glomus tympanicum (GT) is a benign primary tumor of the middle ear. The evolution of endoscopic ear surgery has allowed for an alternative approach to managing this vascular tumor. The purpose of this study was to evaluate an endoscopic approach in GT surgery, and also to investigate its applicability and feasibility. Materials and Methods: Prospectively, 13 class I and II patients, according to the Glasscock-Jackson glomus classification, were candidates for management via a transcanal endoscopic approach...
November 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29381543/first-safety-and-performance-evaluation-of-t45k-a-self-assembling-peptide-barrier-hemostatic-device-after-skin-lesion-excision
#13
George Rahmani, Jayne Prats, Terrence Norchi, Steven Kates, Veronica McInerney, Jack Woods, Jack Kelly
BACKGROUND: The self-assembling peptide barrier T45K (SAPB-T45K) is an oligopeptide that rapidly forms a biocompatible hemostatic barrier when applied to wounds. OBJECTIVE: Evaluate safety and performance of SAPB-T45K in cutaneous surgery. MATERIALS AND METHODS: In this single-blind study, after sequential shave excision of 2 lesions, wounds were randomized (intrapatient) to SAPB-T45K or control treatment. Safety was assessed at treatment, Day 7, and Day 30...
January 29, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29374918/-comparison-of-hysteroscopy-and-curettage-in-incomplete-pregnancy-with-cesarean-scar-pregnancy
#14
L Zhao, H Yang, B R Ma, Z H Yin
Objectives: To evaluate the value of hysteroscopy in the diagnosis and treatment of cesarean scar pregnancy (CSP) incomplete abortion. Methods: A total of 42 patients with incomplete cesarean circumcision from January 2014 to March 2017 were retrospectively analyzed.Twenty-one patients underwent bilateral uterine artery embolization.Twenty patients underwent hysteroscopy Electrocardiose resection of pregnancy tissue and coagulation hemostasis, the control group of 22 patients underwent conventional uterine artery embolization surgery...
January 16, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29352439/single-incision-laparoscopic-transgastric-underrunning-and-closure-of-cameron-ulcers-in-acute-gastrointestinal-bleeding
#15
Chun Han Nigel Tan, Guowei Kim, Jimmy So, Asim Shabbir
INTRODUCTION: Endoscopic therapy remains the cornerstone of hemostasis for gastrointestinal bleeding. In situations where hemostasis cannot be achieved via endoscopic or radiological methods, surgery is necessary. Traditional open surgery for bleeding gastric ulcers can be very morbid and unsuitable especially in hemodynamically unstable patients in extremis. We describe a minimally invasive, transgastric approach for underrunning and closure of Cameron ulcers. METHODS: Our patient is a 75-year-old Chinese lady, who presented to the emergency department with fresh melena...
January 19, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29351677/use-of-risk-model-for-assessment-of-residents-perception-of-complexity-of-surgical-steps-example-of-modular-component-steps-of-lumbar-spinal-fusion-surgery
#16
Jeffrey S Raskin, Jesse J Liu, Katherine Holste, Sarah Brown, Fran Hardaway, Priscilla Pang, Ahmed M Raslan
BACKGROUND: Quality improvement projects increasingly emphasize standardization of surgical work flow to optimize operative room efficiency. Removing special cause variability resulting from nonsurgical waste is an obvious target; however, resident surgical education must be maintained, even in the setting of process improvement. OBJECTIVE: To describe the impact of resident-identified "risky" or "uncomfortable" procedural steps on operative time during transforaminal lumbar interbody fusion (TLIF)...
February 1, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29337125/facilitating-hemostasis-after-proximal-aortic-surgery-results-of-the-protect-trial
#17
Ali Khoynezhad, Jacob DelaRosa, Marc R Moon, William T Brinkman, Richard B Thompson, Nimesh D Desai, S Chris Malaisrie, Leonard N Girardi, Joseph E Bavaria, T Brett Reece
BACKGROUND: This study intended to evaluate the safety and hemostatic efficacy of a novel vascular sealant (Tridyne™ , Neomend, Inc., Irvine, CA) compared to an accepted adjunctive hemostatic agent applied to aortotomy and sutures lines in cardiovascular surgery. METHODS: Subjects undergoing aortic valve replacement, ascending aortic replacement and/or aortic root replacement were randomized 2:1 to Tridyne™ (n =107) or Gelfoam®+ (Gelfoam®+, Baxter Healthcare Corp...
January 11, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29332723/a-method-using-simple-stitches-around-the-safety-margin-for-hemostasis-in-scalp-surgery
#18
Ival Peres Rosa, Sergio Henrique Hirata, Mauro Yoshiaki Enokihara, Caroline Benevides Farkas, Anamaria da Silva Facina
No abstract text is available yet for this article.
February 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29321420/validity-of-the-pre-endoscopic-scoring-systems-for-the-prediction-of-the-failure-of-endoscopic-hemostasis-in-bleeding-gastroduodenal-peptic-ulcers
#19
Chikara Iino, Tadashi Shimoyama, Takasato Igarashi, Tomoyuki Aihara, Kentaro Ishii, Jyuichi Sakamoto, Hiroshi Tono, Shinsaku Fukuda
Background and Aim Although several pre-endoscopic scoring systems have been used to predict the mortality or the need for intervention for upper gastrointestinal bleeding, their usefulness to predict the failure of endoscopic hemostasis in bleeding gastroduodenal peptic ulcers has not yet been fully investigated. In this study, we evaluated the usefulness of the Glasgow-Blatchford score (GBS), the clinical Rockall score (CRS), and the AIMS65 score in predicting the failure of endoscopic hemostasis in patients with bleeding gastroduodenal peptic ulcers...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29319638/anomalous-sphenoid-diploe-vein-case-report-highlighting-the-value-of-careful-ct-evaluation-prior-to-decompression-surgery
#20
Michael Rafaelof, Hamzah Mustak, Daniel B Rootman
Lateral bony decompression may offer several biomechanical advantages and has become a commonly used surgical approach. Preoperative imaging plays a key role in surgical planning by providing information about the locoregional anatomy. The marrow space of the greater wing of the sphenoid is a focal point of the decompression surgery based on the volume that it occupies. Several vessels pass through the sphenoid bone, but most are small caliber vessels. The authors describe a case of an uncommon anatomical variant of the cranial diploic venous system in which the anterior transverse diploic vessel traverses the marrow space of the sphenoid...
January 9, 2018: Ophthalmic Plastic and Reconstructive Surgery
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