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https://www.readbyqxmd.com/read/27910996/speckle-tracking-echocardiography-predicts-early-subclinical-anthracycline-cardiotoxicity-in-patients-with-breast-cancer
#1
Qi Tang, Yan Jiang, Yali Xu, Hongmei Xia
PURPOSE: This study aimed to assess the early changes of left ventricular (LV) and right ventricular (RV) mechanics associated with anthracycline treatment for breast cancer and to determine whether two-dimensional speckle tracking echocardiography (2D-STE) analysis could predict chemotherapy-induced cardiotoxicity. BACKGROUND: Anthracycline generates progressive LV dysfunction associated with a poor prognosis. Early detection of minor change of myocardial mechanics is thus important...
December 2, 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27909859/sofa-score-and-left-ventricular-systolic-function-as-predictors-of-short-term-outcome-in-patients-with-sepsis
#2
Francesca Innocenti, Vittorio Palmieri, Aurelia Guzzo, Valerio Teodoro Stefanone, Chiara Donnini, Riccardo Pini
In a group of septic patients, we assess the short-term prognostic value of LV systolic performance, evaluated through conventional left ventricular ejection fraction (LVEF) and left ventricular global longitudinal strain (LV GLS). One hundred forty-seven patients with sepsis were recruited; LVEF by planimetry and peak GLS by 2D speckle tracking could be assessed within 24 h. The study population was stratified according to SOFA tertiles assessed at the time of the echocardiogram (G1: SOFA score <5; G2: SOFA score 5-7; G3: SOFA score >7)...
December 1, 2016: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/27908646/left-ventricular-function-in-healthy-term-neonates-during-the-transitional-period
#3
Amish Jain, Afif F El-Khuffash, Bart C W Kuipers, Adel Mohamed, Kim A Connelly, Patrick J McNamara, Robert P Jankov, Luc Mertens
OBJECTIVES: To evaluate whether incorporating conventional, tissue Doppler imaging and speckle tracking echocardiography are reliable and can characterize changes in left ventricular (LV) function properly in healthy neonates in the early transitional newborn period. STUDY DESIGN: A prospective observational study was conducted in 50 healthy term neonates with a mean ± SD gestational age and birth weight of 39.3 ± 1.2 weeks and 3.5 ± 0.44 kg, respectively...
November 28, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27898434/the-continuing-challenge-of-evaluating-diastolic-function-by-echocardiography-in-children-developing-concepts-and-newer-modalities
#4
Wadi Mawad, Mark K Friedberg
PURPOSE OF REVIEW: Assessment of diastolic function by echocardiography is challenging but important. Left ventricular filling has been more extensively studied than the right ventricle, and predominantly in adult populations. Although multiple parameters exist to assess diastolic function, they all have limitations, including load and heart rate dependency, which make assessment of diastolic function particularly challenging. The purpose of this article is to review evolving concepts and modalities for echo assessment of diastolic function in children...
January 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/27890871/chagas-disease-in-mexico-report-of-14-cases-of-chagasic-cardiomyopathy-in-children
#5
Paz María Salazar-Schettino, Margarita Cabrera-Bravo, Clara Vazquez-Antona, Edgar Zenteno, Mariana De Alba-Alvarado, Elia Torres Gutierrez, Yolanda Guevara Gomez, María Gabriela Perera-Salazar, Guadalupe Garcia de la Torre, Martha Irene Bucio-Torres
Chagas disease is a parasitic infection mainly found in Latin America; it is transmitted by a triatomine, also known as assassin bug or kissing bug. In humans, the parasite causes mostly cardiac disorders. Two-thirds of the Mexican territory are regarded as risk areas for vector transmission of Trypanosoma cruzi, the causal agent. The parasite can be found as a blood-borne trypomastigote or as an intracellular amastigote. The progression and severity of lesions could be due to frequent reinfections or to infection by highly virulent strains...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27889554/familial-dilated-cardiomyopathy-a-multidisciplinary-entity-from-basic-screening-to-novel-circulating-biomarkers
#6
REVIEW
D de Gonzalo-Calvo, M Quezada, O Campuzano, A Perez-Serra, J Broncano, R Ayala, M Ramos, V Llorente-Cortes, S Blasco-Turrión, F J Morales, P Gonzalez, R Brugada, A Mangas, R Toro
Idiopathic dilated cardiomyopathy has become one of the most prevalent inherited cardiomyopathies over the past decades. Genetic screening of first-degree relatives has revealed that 30-50% of the cases have a familial origin. Similar to other heart diseases, familial dilated cardiomyopathy is characterized by a high genetic heterogeneity that complicates family studies. Cli'nical screening, 12-lead electrocardiogram and transthoracic echocardiogram are recommended for patients and first-degree family members...
November 8, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27885496/descending-aortic-mechanics-and-atrial-fibrillation-a-two-dimensional-speckle-tracking-transesophageal-echocardiography-study
#7
Rogério Teixeira, Ricardo Monteiro, Paulo Dinis, Maria José Santos, Ana Botelho, Nuno Quintal, Nuno Cardim, Lino Gonçalves
Vascular mechanics assessed with two-dimensional speckle tracking echocardiography (2D-STE) could be used as a new imaging surrogate of vascular stiffening. The CHA2DS2-VASc score is considered accurate as an estimate of stroke risk in non-valvular AF, although many potential stroke risk factors have not been included in this scoring method. The purpose of this research is to study the feasibility of evaluating vascular mechanics at the descending aorta in non-valvular AF patients using transesophageal 2D-STE and to analyze the association between descending aortic mechanics and stroke...
November 24, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27885494/comparison-of-arterial-stiffness-compliance-in-the-ascending-aorta-and-common-carotid-artery-in-healthy-subjects-and-its-impact-on-left-ventricular-structure-and-function
#8
Olga Vriz, Julien Magne, Caterina Driussi, Gabriele Brosolo, Francesco Ferrara, Paolo Palatini, Victor Aboyans, Eduardo Bossone
Arterial stiffness and compliance parameters from two adjacent elastic arteries [aorta and common carotid artery (CCA)] were compared and their relationship with left ventricular (LV) structure and function and clinical parameters was assessed. 584 healthy subjects were prospectively enrolled [mean age 47.8 ± 18.4 years, range 16-94; 318 (54.4%) men]. They underwent comprehensive transthoracic echocardiography; M-mode diameters were measured at the level of the ascending aorta in systole and diastole and by echo-tracking at the level of the left CCA...
November 24, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27862239/quantitative-echocardiographic-measures-in-the-assessment-of-single-ventricle-function-post-fontan-incorporation-into-routine-clinical-practice
#9
Rodrigo Rios, Salil Ginde, David Saudek, Rohit S Loomba, Jessica Stelter, Peter Frommelt
BACKGROUND: Quantitative echocardiographic measurements of single ventricular (SV) function have not been incorporated into routine clinical practice. METHODS: A clinical protocol, which included quantitative measurements of SV deformation (global circumferential and longitudinal strain and strain rate), standard deviation of time to peak systolic strain, myocardial performance index (MPI), dP/dT from an atrioventricular valve regurgitant jet, and superior mesenteric artery resistance index, was instituted for all patients with a history of Fontan procedure undergoing echocardiography...
November 16, 2016: Echocardiography
https://www.readbyqxmd.com/read/27861208/left-ventricular-myocardial-fibrosis-atrophy-and-impaired-contractility-in-patients-with-pulmonary-arterial-hypertension-and-a-preserved-left-ventricular-function-a-cardiac-magnetic-resonance-study
#10
Rami Homsi, Julian A Luetkens, Dirk Skowasch, Carmen Pizarro, Alois M Sprinkart, Juergen Gieseke, Julia Meyer Zur Heide Gen Meyer-Arend, Hans H Schild, Claas P Naehle
PURPOSE: Using a cardiac magnetic resonance (CMR) approach we investigated left ventricular (LV) myocardial changes associated with pulmonary arterial hypertension (PAH) by strain analysis and mapping techniques. MATERIALS AND METHODS: Seventeen patients with PAH (9 men; mean age, 64.2±13.6 y) and 20 controls (10 men, 63.2±10.5 y) were examined using CMR at 1.5 T. Native LV T1-relaxation times (T1) and extracellular volume fraction (ECV) were assessed using a MOLLI sequence, T2-relaxation times (T2) by means of a gradient spin-echo sequence, and LV longitudinal strain (LVS) and right ventricular (RV) longitudinal strain (RVS) by means of CMR feature tracking...
November 16, 2016: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/27858918/global-longitudinal-strain-predicts-incident-atrial-fibrillation-and-stroke-occurrence-after-acute-myocardial-infarction
#11
Flemming Javier Olsen, Sune Pedersen, Jan Skov Jensen, Tor Biering-Sørensen
Patients with acute myocardial infarction are at increased risk of developing atrial fibrillation. We aimed to evaluate whether speckle tracking echocardiography improves risk stratification for atrial fibrillation in these patients.The study comprised of 373 patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention. Patients had an echocardiogram performed at a median of 2 days after their STEMI. The echocardiograms consisted of conventional measurements and myocardial strain analysis by speckle tracking from 3 apical projections...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27858175/an-information-based-machine-learning-approach-to-elasticity-imaging
#12
Cameron Hoerig, Jamshid Ghaboussi, Michael F Insana
An information-based technique is described for applications in mechanical property imaging of soft biological media under quasi-static loads. We adapted the Autoprogressive method that was originally developed for civil engineering applications for this purpose. The Autoprogressive method is a computational technique that combines knowledge of object shape and a sparse distribution of force and displacement measurements with finite-element analyses and artificial neural networks to estimate a complete set of stress and strain vectors...
November 18, 2016: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/27848162/characterizing-the-spectrum-of-right-ventricular-remodelling-in-response-to-chronic-training
#13
Marta Sitges, Beatriz Merino, Constatine Butakoff, Maria Sanz de la Garza, Carles Paré, Silvia Montserrat, Barbara Vidal, Manel Azqueta, Georgia Sarquella, Josep Antoni Gutierrez, Ramon Canal, Josep Brugada, Bart H Bijnens
The significance and spectrum of reduced right ventricular (RV) deformation, reported in endurance athletes, is unclear. To comprehensively analyze the cardiac performance at rest of athletes, especially focusing on integrating RV size and deformation to unravel the underlying triggers of this ventricular remodelling. Hundred professional male athletes and 50 sedentary healthy males of similar age were prospectively studied. Conventional echocardiographic parameters of all four chambers were obtained, as well as 2D echo-derived strain (2DSE) in the left (LV) and in the RV free wall with separate additional analysis of the RV basal and apical segments...
November 15, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27845956/the-association-of-night-time-systolic-blood-pressure-with-ultrasound-markers-of-subclinical-cardiac-and-vascular-disease
#14
Anne Marie O'Flynn, Emily Ho, Eamon Dolan, Ronan J Curtin, Patricia M Kearney
INTRODUCTION: The aim of this study was to examine the association of night-time systolic blood pressure (BP) with subclinical cardiac dysfunction measured by global longitudinal strain (GLS) and subclinical vascular damage measured by carotid intima-media thickness (CIMT) and carotid plaques. METHODS: GLS was measured by speckle-tracking analysis of echocardiogram images. CIMT was measured at the distal 1 cm of the common carotid artery. The presence of carotid plaques was recorded...
November 11, 2016: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/27824609/prospective-validation-of-right-ventricular-role-in-primary-graft-dysfunction-after-lung-transplantation
#15
Purificación Pérez-Terán, Oriol Roca, José Rodríguez-Palomares, Juan C Ruiz-Rodríguez, Ana Zapatero, Joaquim Gea, Joaquim Serra, Arturo Evangelista, Joan R Masclans
Primary graft dysfunction is a significant cause of lung transplant morbidity and mortality, but its underlying mechanisms are not completely understood. The aims of the present study were: 1) to confirm that right ventricular function is a risk factor for severe primary graft dysfunction; and 2) to propose a clinical model for predicting the development of severe primary graft dysfunction.A prospective cohort study was performed over 14 months. The primary outcome was development of primary graft dysfunction grade 3...
December 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/27807020/miliary-tuberculosis-in-an-immunocompetent-male-with-a-fatal-outcome
#16
Louise Dunphy, Elizabeth Keating, T Parke
A man aged 33 years, born in Nepal, but resident in the UK for 7 years presented to the emergency department with a 4-day history of general malaise, fever (temperature 38.6°C) and a non-productive cough. His medical history was unremarkable and no high-risk behaviour was identified. Clinical examination confirmed decreased air entry bilaterally with bibasal crackles. He was tachycardic, with a heart rate of 120 bpm. Further investigation with a 12-lead ECG confirmed supraventricular tachycardia (SVT) which was terminated with vagal manoeuvres...
November 2, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27793158/clinical-and-echocardiographic-predictors-of-mortality-in-acute-pulmonary-embolism
#17
Talal Dahhan, Irfan Siddiqui, Victor F Tapson, Eric J Velazquez, Stephanie Sun, Clemontina A Davenport, Zainab Samad, Sudarshan Rajagopal
PURPOSE: The aim of this study was to evaluate the utility of adding quantitative assessments of cardiac function from echocardiography to clinical factors in predicting the outcome of patients with acute pulmonary embolism (PE). METHODS: Patients with a diagnosis of acute PE, based on a positive ventilation perfusion scan or computed tomography (CT) chest angiogram, were identified using the Duke University Hospital Database. Of these, 69 had echocardiograms within 24-48 h of the diagnosis that were suitable for offline analysis...
October 28, 2016: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/27782943/preoperative-three-dimensional-strain-imaging-identifies-reduction-in-left-ventricular-function-and-predicts-outcomes-after-cardiac-surgery
#18
Kimberly Howard-Quijano, Ali Salem, Charles Barkulis, Einat Mazor, Jennifer C Scovotti, Jonathan K Ho, Richard J Shemin, Tristan Grogan, David Elashoff, Aman Mahajan
BACKGROUND: Echocardiography-based speckle-tracking strain imaging is an emerging modality to assess left ventricular function. The aim of this study was to investigate the change in left ventricular systolic function after cardiac surgery with 3-dimensional (3D) speckle-tracking strain imaging and to determine whether preoperative 3D strain is an independent predictor of acute and long-term clinical outcomes after aortic valve, mitral valve, and coronary artery bypass grafting operations...
October 24, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27754006/js-ish-esh-2-update-on-the-detection-and-follow-up-of-early-hypertensive-heart-disease
#19
Enrico Agabiti Rosei
Current Hypertension Guidelines emphasize the importance of assessing the presence of preclinical organ damage. In fact, an extensive evaluation of organ damage may increase the number of patients classified at high CV risk and therefore strongly influence the clinical management of patients. Hypertensive heart disease remains to date the form of organ damage for which there is the greatest amount of evidence of a strong independent prognostic significance. In the presence of a chronic pressure overload, a parallel addition of sarcomers takes place with an increase in myocyte width, which in turn increases left ventricular wall thickness; myocyte hypertrophy is also associated with apoptosis, collagen deposition and ventricular fibrosis with an impairment of coronary hemodynamics as well, thus profoundly influencing functional properties of the left (and right) ventricle...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27739163/interpreting-measurements-of-cardiac-function-using-vendor-independent-speckle-tracking-echocardiography-in-children-a-prospective-blinded-comparison-with-catheter-derived-measurements
#20
Suma P Goudar, G Hamilton Baker, Shahryar M Chowdhury, Kimberly J Reid, Girish Shirali, Mark A Scheurer
BACKGROUND: Adult studies demonstrate that echocardiographic measurements of cardiac function using speckle tracking correlate with invasive measurements, but such data in the pediatric population are sparse. Our aim was to compare speckle-derived measures of cardiac function to measurements routinely obtained by cardiac catheterization in children. METHODS: Echocardiograms were performed on the day of cardiac catheterization. Using Tomtec 2D Cardiac Performance Analysis, longitudinal strain (LS), longitudinal strain rate (LSR), early diastolic LSR, and ejection fraction (EF) for the right and left ventricle (RV and LV) were calculated via speckle tracking...
October 14, 2016: Echocardiography
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