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https://www.readbyqxmd.com/read/28403873/weight-change-during-chemotherapy-in-breast-cancer-patients-a-meta-analysis
#1
M M G A van den Berg, R M Winkels, J Th C M de Kruif, H W M van Laarhoven, M Visser, J H M de Vries, Y C de Vries, E Kampman
BACKGROUND: Weight gain during chemotherapy in women with breast cancer is commonly reported. However, there are important differences between studies that examined weight change during chemotherapy; e.g. type of chemotherapy, menopausal status, time between body weight measurements and sample size. The purpose of this meta-analysis was to quantify changes in body weight during chemotherapy for women with breast cancer, taking these differences into account. METHODS: We identified relevant studies using PubMed, Scopus and Embase databases...
April 12, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28392045/low-prevalence-of-zoonotic-babesia-in-small-mammals-and-ixodes-ricinus-in-brittany-france
#2
M Jouglin, G Perez, A Butet, L Malandrin, S Bastian
In order to evaluate the zoonotic risk due to Babesia spp., especially B. microti, we investigated their presence in 597 individuals of five small mammal species and in 2620 questing nymphs of Ixodes ricinus in rural landscapes of Western France (Brittany). Small mammals (rodents and shrews) are indeed suspected to be reservoir hosts for B. microti, and the tick I. ricinus is the vector of the three main zoonotic species in Europe, i.e. B. divergens, B. venatorum and B. microti. Only one bank vole carried B...
March 25, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28291735/cd4-cd8-ratio-comparison-between-cohorts-of-hiv-positive-asians-and-caucasians-upon-commencement-of-antiretroviral-therapy
#3
Kathy Petoumenos, Jun Yong Choi, Jennifer Hoy, Sasisopin Kiertiburanakul, Oon Tek Ng, Mark Boyd, Reena Rajasuriar, Matthew Law
BACKGROUND: In the era of effective antiretroviral treatment (ART) CD4:CD8 ratio is proposed as a potential marker for HIV-positive (HIV+) patients at increased risk for non-AIDS comorbidities. The current study aims to compare CD4:CD8 ratio between Asian and Caucasian HIV+ patients. METHODS: HIV+ patients from the Australian HIV Observational Database (AHOD) and the TREAT Asia HIV Observational Database (TAHOD) meeting specific criteria were included. In these analyses Asian and Caucasian status were defined by cohort...
March 14, 2017: Antiviral Therapy
https://www.readbyqxmd.com/read/28163942/further-evidence-that-the-cftr-variant-c-2620-6t-c-is-benign
#4
Violet I Wallerstein, Robert Wallerstein
The c.2620-6T>C variant in the CFTR gene is a rare variant about which little is known. We present an asymptomatic adult who has this variant as well as the well described delta F508 pathogenic variant in transpresentation. This patient provides additional evidence that this is a benign polymorphism.
2017: Case Reports in Genetics
https://www.readbyqxmd.com/read/28150119/second-generation-versus-first-generation-drug-eluting-stents-in-patients-with-and-without-diabetes-mellitus-pooled-analysis-from-the-reset-and-next-trials
#5
Kenji Nakatsuma, Hiroki Shiomi, Masahiro Natsuaki, Takeshi Morimoto, Keiichi Igarashi, Kazushige Kadota, Toshiya Muramatsu, Kengo Tanabe, Yoshihiro Morino, Takashi Akasaka, Yoshihisa Nakagawa, Ken Kozuma, Takeshi Kimura
The impact of second-generation drug-eluting stent (G2-DES) implantations compared with first-generation drug-eluting stents (G1-DES) implantations on long-term clinical outcomes after percutaneous coronary intervention in patients with and without diabetes mellitus (DM) has not yet been adequately assessed. This pooled analysis compared 3-year clinical outcomes between G1- and G2-DES according to the presence or absence of DM, using individual patient-level data from the RESET and NEXT trials. Among 6431 patients, G1-DES and G2-DES were used in 713 and 2211 patients, respectively, in the DM stratum, and 887 and 2620 patients, respectively, in the non-DM stratum...
February 1, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28097361/folic-acid-supplementation-for-the-prevention-of-neural-tube-defects-an-updated-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#6
REVIEW
Meera Viswanathan, Katherine A Treiman, Julia Kish-Doto, Jennifer C Middleton, Emmanuel J L Coker-Schwimmer, Wanda K Nicholson
Importance: Neural tube defects are among the most common congenital anomalies in the United States. Periconceptional folic acid supplementation is a primary care-relevant preventive intervention. Objective: To review the evidence on folic acid supplementation for preventing neural tube defects to inform the US Preventive Services Task Force for an updated Recommendation Statement. Data Sources: MEDLINE, Cochrane Library, EMBASE, and trial registries through January 28, 2016, with ongoing surveillance through November 11, 2016; references; experts...
January 10, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28060067/patients-with-dry-eye-disease-and-low-subbasal-nerve-density-are-at-high-risk-for-accelerated-corneal-endothelial-cell-loss
#7
Ahmad Kheirkhah, Vannarut Satitpitakul, Pedram Hamrah, Reza Dana
PURPOSE: To evaluate changes in corneal endothelial cell density over time in patients with dry eye disease (DED) and to correlate endothelial cell loss with corneal subbasal nerve density. METHODS: This retrospective study included 40 eyes of 20 patients with DED. Laser in vivo confocal microscopy had been performed in the central cornea of both eyes at an initial visit and repeated after a mean follow-up of 33.2 ± 10.2 months. The densities of corneal endothelial cells and subbasal nerves were measured in both visits and compared with 13 eyes of 13 normal age-matched controls...
February 2017: Cornea
https://www.readbyqxmd.com/read/28040058/cystic-fibrosis-transmembrane-conductance-regulator-cftr-gene-mutations-in-north-egyptian-population-implications-for-the-genetic-diagnosis-in-egypt
#8
A El-Seedy, M C Pasquet, H Shafiek, T Morsi, A Kitzis, V Ladevèze
Cystic fibrosis (CF) occurrence in Arab populations is not common and still remains underidentified. Furthermore, the lack of disease awareness and diagnosis facilities have mislead the identification of cystic fibrosis for decades. The knowledge about cystic fibrosis (CF) in Egypt is very limited, and a few reports have drawn attention to the existence of CF or CFTR-related disorders (CFTR-RDs) in the Egyptian population. Therefore a comprehensive genetic analysis of the CFTR gene was realized in patients of North Egypt...
November 30, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/27924517/prostate-volume-growth-rate-changes-over-time-results-from-men-18-to-92-years-old-in-a-longitudinal-community-based-study
#9
Si-Hui Li, Qun-Fang Yang, Pei-Yuan Zuo, Yu-Wei Liu, Yu-Hua Liao, Cheng-Yun Liu
Previous investigations have shown that changes in total prostate volume (TPV) are highly variable among aging men, and a considerable proportion of aging men have a stable or decreasing prostate size. Although there is an abundance of literature describing prostatic enlargement in association with benign prostatic hyperplasia, less is known about the appropriate age cut-off points for TPV growth rate. In this community-based cohort study, TPV was examined once a year in men who had consecutive health checkup, during a follow-up of 4 years...
December 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27911268/texture-analysis-of-intermediate-advanced-hepatocellular-carcinoma-prognosis-and-patients-selection-of-transcatheter-arterial-chemoembolization-and-sorafenib
#10
Sirui Fu, Shuting Chen, Changhong Liang, Zaiyi Liu, Yanjie Zhu, Yong Li, Ligong Lu
Transcatheter arterial chemoembolization (TACE) and sorafenib combination treatment for unselected hepatocellular carcinoma (HCC) is controversial. We explored the potential of texture analysis for appropriate patient selection. There were 261 HCCs included (TACE group: n = 197; TACE plus sorafenib (TACE+Sorafenib) group n = 64). We applied a Gabor filter and wavelet transform with 3 band-width responses (filter 0, 1.0, and 1.5) to portal-phase computed tomography (CT) images of the TACE group. Twenty-one textural parameters per filter were extracted from the region of interests delineated around tumor outline...
November 29, 2016: Oncotarget
https://www.readbyqxmd.com/read/27869854/experimental-investigation-on-supercontinuum-generation-by-single-dual-and-triple-wavelength-pumping-in-a-silica-photonic-crystal-fiber
#11
Weiqing Gao, Qiang Xu, Xue Li, Wei Zhang, Jigang Hu, Yuan Li, Xiangdong Chen, Zijun Yuan, Meisong Liao, Tonglei Cheng, Xiaojie Xue, Takenobu Suzuki, Yasutake Ohishi
We investigate the supercontinuum (SC) generation in an 1 cm long silica photonic crystal fiber (PCF) pumped by the pulse sources with single, dual, and triple wavelengths, respectively. The silica PCF has two zero-dispersion wavelengths at 900 and 2620 nm, respectively. When pumped by a single wavelength, the SC spectral range covers about 1000 nm. When pumped by dual and triple wavelengths, the SC spectral range covers wider than 2000 nm. Both the SC spectral range and the flatness are improved obviously when pumped by triple wavelengths...
November 20, 2016: Applied Optics
https://www.readbyqxmd.com/read/27811567/patients-with-dry-eye-disease-and-low-subbasal-nerve-density-are-at-high-risk-for-accelerated-corneal-endothelial-cell-loss
#12
Ahmad Kheirkhah, Vannarut Satitpitakul, Pedram Hamrah, Reza Dana
PURPOSE: To evaluate changes in corneal endothelial cell density over time in patients with dry eye disease (DED) and to correlate endothelial cell loss with corneal subbasal nerve density. METHODS: This retrospective study included 40 eyes of 20 patients with DED. Laser in vivo confocal microscopy had been performed in the central cornea of both eyes at an initial visit and repeated after a mean follow-up of 33.2 ± 10.2 months. The densities of corneal endothelial cells and subbasal nerves were measured in both visits and compared with 13 eyes of 13 normal age-matched controls...
November 2, 2016: Cornea
https://www.readbyqxmd.com/read/27807730/longitudinal-radiographic-behavior-of-accessory-navicular-in-pediatric-patients
#13
Derrick M Knapik, Sahejmeet S Guraya, Keegan T Conry, Daniel R Cooperman, Raymond W Liu
BACKGROUND: An accessory navicular is generally asymptomatic and discovered incidentally on radiographs. The natural history of an accessory navicular in the pediatric population is largely undescribed. METHODS: The medical charts of 261 pediatric subjects undergoing 2620 annual unilateral radiographs of the foot and ankle (age range 0.25-7 years at enrollment) were reviewed. Radiographs were examined to determine the incidence of accessory navicular, with focus on the age at appearance and, if present, the age at fusion...
December 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27759187/proportion-of-patients-with-hypertension-resolution-following-adrenalectomy-for-primary-aldosteronism-a-systematic-review-and-meta-analysis
#14
Jamie L Benham, Maysoon Eldoma, Bushra Khokhar, Derek J Roberts, Doreen M Rabi, Gregory A Kline
Unilateral primary aldosteronism (PA) is often treated with adrenalectomy, but hypertension resolution rates are variable. A valid estimate of the postoperative normotension rate is necessary to inform the utility of PA testing and treatment. The authors searched MEDLINE In-Process & Other Non-Indexed Citations, Embase, and Cochrane Central Register of Controlled Trials. Prospective adult cohort studies with surgically treated PA that reported resolution of hypertension without the aid of medications were included...
December 2016: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/27754203/apsh-yi-02-the-polymorphism-in-aldehyde-dehydrogenase-2-aldh2-gene-is-associated-with-myocardial-infarction-and-stroke-in-a-chinese-population
#15
Xin Liu, Weirong Chen, Hongye Zhang, Wei Zhang, Lisheng Liu, Xingyu Wang
OBJECTIVE: Objective: Alcohol consumption has an important effect on coronary atherosclerotic heart disease (CAD). Acetaldehyde dehydrogenase 2 (ALDH2) is a key enzyme in alcohol metabolism. A G-to-A missense mutation of ALDH2 gene, rs671, which causes a Glu > Lys (504) substitution, was performed to detect the association with CAD and other relative diseases, but the results were not conclusive. The purpose of the present study was to determine whether this locus confers significant susceptibility to myocardial infarction and stroke in a Chinese population...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27749155/personality-health-behaviors-and-quality-of-life-among-colorectal-cancer-survivors-results-from-the-profiles-registry
#16
Olga Husson, Johan Denollet, Nicole P M Ezendam, Floortje Mols
PURPOSE: There is a paucity of research looking into the relationship between personality and health behaviors among cancer survivors. The aim of this study was to investigate whether Type D personality and its two constituent components, negative affectivity (NA) and social inhibition (SI), are associated with health behaviors, quality of life (QoL), and mental distress among colorectal cancer (CRC) survivors. METHODS: A population-based study was conducted among 2,620 CRC patients diagnosed between 2000 and 2009, who completed measures of personality (DS14), health behaviors, QoL (EORTC QLQ-C30), and mental distress (hospital anxiety and depression scale)...
January 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/27747528/evaluation-of-the-stiffness-characteristics-of-rapid-palatal-expander-screws
#17
Luca Lombardo, Enrico Sacchi, Maria Larosa, Francesco Mollica, Valentina Mazzanti, Giorgio Alfredo Spedicato, Giuseppe Siciliani
BACKGROUND: The aim of this study is to evaluate the mechanical properties of the screws used for rapid expansion of the upper jaw. METHODS: Ten types of expansion screw were assessed, seven with four arms: Lancer Philosophy 1, Dentaurum Hyrax Click Medium, Forestadent Anatomic Expander type "S", Forestadent Anatomic Expander type "S" for narrow palates, Forestadent Memory, Leone A 2620-10 with telescopic guide, and Leone A 0630-10 with orthogonal arms; and three with two arms: Dentaurum Variety S...
December 2016: Progress in Orthodontics
https://www.readbyqxmd.com/read/27734524/bendamustine-associated-infections-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#18
Anat Gafter-Gvili, Ronit Gurion, Pia Raanani, Ofer Shpilberg, Liat Vidal
Data in the literature are lacking regarding the infection-related adverse events of bendamustine-containing regimens. Therefore, we aimed to assess this risk. We conducted a systematic review and meta-analysis of all randomized controlled trials including bendamustine-containing regimens and those administered for any lymphoproliferative disorder or plasma cell dyscrasia compared with any other regimens. A comprehensive search was conducted until December 2015. Two reviewers appraised the quality of trials and extracted data...
October 13, 2016: Hematological Oncology
https://www.readbyqxmd.com/read/27643160/apsh-yi-02-the-polymorphism-in-aldehyde-dehydrogenase-2-aldh2-gene-is-associated-with-myocardial-infarction-and-stroke-in-a-chinese-population
#19
Xin Liu, Weirong Chen, Hongye Zhang, Wei Zhang, Lisheng Liu, Xingyu Wang
OBJECTIVE: HASH(0x32911e8) OBJECTIVE: Alcohol consumption has an important effect on coronary atherosclerotic heart disease (CAD). Acetaldehyde dehydrogenase 2 (ALDH2) is a key enzyme in alcohol metabolism. A G-to-A missense mutation of ALDH2 gene, rs671, which causes a Glu > Lys (504) substitution, was performed to detect the association with CAD and other relative diseases, but the results were not conclusive. The purpose of the present study was to determine whether this locus confers significant susceptibility to myocardial infarction and stroke in a Chinese population...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27525396/-influenza-surveillance-in-five-consecutive-seasons-during-post-pandemic-period-results-from-national-influenza-center-turkey
#20
Ayşe Başak Altaş, Fatma Bayrakdar, Gülay Korukluoğlu
Influenza surveillance provides data about the characteristics of influenza activity, types, sub-types and antigenic properties of the influenza viruses in circulation in a region. Surveillance also provides for the preparation against potential influenza pandemics with the identification of the genetic properties of viruses and the mutant strains that could pose a threat. In this study, data in the scope of national influenza surveillance carried out by National Influenza Center, Turkey for five consecutive influenza seasons between 2010-2015, following the A(H1N1)pdm09 virus pandemic, have been presented and evaluated...
July 2016: Mikrobiyoloji Bülteni
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