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Olga Husson, Johan Denollet, Nicole P M Ezendam, Floortje Mols
PURPOSE: There is a paucity of research into the relationship between personality and health behaviors among cancer survivors. The aim of this study was to investigate whether Type D personality and its two constituent components, negative affectivity (NA) and social inhibition (SI), are associated with health behaviors, quality of life (QoL) and mental distress among colorectal cancer (CRC) survivors. METHODS: Population-based study among 2620 CRC patients diagnosed between 2000-2009 who completed measures of personality (DS14), health behaviors, QoL (EORTC QLQ-C30) and mental distress (HADS)...
October 17, 2016: Journal of Psychosocial Oncology
Luca Lombardo, Enrico Sacchi, Maria Larosa, Francesco Mollica, Valentina Mazzanti, Giorgio Alfredo Spedicato, Giuseppe Siciliani
BACKGROUND: The aim of this study is to evaluate the mechanical properties of the screws used for rapid expansion of the upper jaw. METHODS: Ten types of expansion screw were assessed, seven with four arms: Lancer Philosophy 1, Dentaurum Hyrax Click Medium, Forestadent Anatomic Expander type "S", Forestadent Anatomic Expander type "S" for narrow palates, Forestadent Memory, Leone A 2620-10 with telescopic guide, and Leone A 0630-10 with orthogonal arms; and three with two arms: Dentaurum Variety S...
December 2016: Progress in Orthodontics
Anat Gafter-Gvili, Ronit Gurion, Pia Raanani, Ofer Shpilberg, Liat Vidal
Data in the literature are lacking regarding the infection-related adverse events of bendamustine-containing regimens. Therefore, we aimed to assess this risk. We conducted a systematic review and meta-analysis of all randomized controlled trials including bendamustine-containing regimens and those administered for any lymphoproliferative disorder or plasma cell dyscrasia compared with any other regimens. A comprehensive search was conducted until December 2015. Two reviewers appraised the quality of trials and extracted data...
October 13, 2016: Hematological Oncology
Xin Liu, Weirong Chen, Hongye Zhang, Wei Zhang, Lisheng Liu, Xingyu Wang
OBJECTIVE: HASH(0x42dcb00) OBJECTIVE: Alcohol consumption has an important effect on coronary atherosclerotic heart disease (CAD). Acetaldehyde dehydrogenase 2 (ALDH2) is a key enzyme in alcohol metabolism. A G-to-A missense mutation of ALDH2 gene, rs671, which causes a Glu > Lys (504) substitution, was performed to detect the association with CAD and other relative diseases, but the results were not conclusive. The purpose of the present study was to determine whether this locus confers significant susceptibility to myocardial infarction and stroke in a Chinese population...
September 2016: Journal of Hypertension
Ayşe Başak Altaş, Fatma Bayrakdar, Gülay Korukluoğlu
Influenza surveillance provides data about the characteristics of influenza activity, types, sub-types and antigenic properties of the influenza viruses in circulation in a region. Surveillance also provides for the preparation against potential influenza pandemics with the identification of the genetic properties of viruses and the mutant strains that could pose a threat. In this study, data in the scope of national influenza surveillance carried out by National Influenza Center, Turkey for five consecutive influenza seasons between 2010-2015, following the A(H1N1)pdm09 virus pandemic, have been presented and evaluated...
July 2016: Mikrobiyoloji Bülteni
Xiaoyuan Zhu, Ying Wang, Honghai Zhu, Weihua Lou
CONCLUSION: HPV + HNSCC patients have improved Overall Survival (OS), Disease Specific Survival (DSS), Disease Free Survival (DFS), and Progression Free Survival (PFS). The radiotherapy treatment can't improve the Survival of the HPV-negative HNSCC patients. OBJECTIVE: To investigate the role of Human papillomavirus in head and neck cancer and the impact on radiotherapy outcome. METHODS: A search in PubMed and Chinese CNKI (2000-2015) was performed...
July 29, 2016: Acta Oto-laryngologica
Haidong Lan, Yuandong Chan, Kai Xu, Bertil Schmidt, Shaoliang Peng, Weiguo Liu
BACKGROUND: Computing alignments between two or more sequences are common operations frequently performed in computational molecular biology. The continuing growth of biological sequence databases establishes the need for their efficient parallel implementation on modern accelerators. RESULTS: This paper presents new approaches to high performance biological sequence database scanning with the Smith-Waterman algorithm and the first stage of progressive multiple sequence alignment based on the ClustalW heuristic on a Xeon Phi-based compute cluster...
2016: BMC Bioinformatics
Thomas Yvert, Hirofumi Zempo, Naoki Kikuchi, Eri Miyamoto-Mikami, Guan Wang, Haruka Murakami, Hisashi Naito, Motohiko Miyachi, Yannis Pitsiladis, Noriyuki Fuku
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Teun Aalbers, Li Qin, Maria Ae Baars, Annet de Lange, Roy Pc Kessels, Marcel Gm Olde Rikkert
BACKGROUND: Our labor force is aging, but aged workers are not yet coached on how to stay cognitively fit for the job. OBJECTIVE: In this study, we tested whether a self-motivated, complex eHealth intervention could improve multiple health-related behaviors that are associated with cognitive aging among working Dutch adults. METHODS: This quasi-experimental prospective study with a pre-post design was conducted with employees of Dutch medium to large companies...
2016: Journal of Medical Internet Research
Xing Liu, Yanli Xu, Qian Meng, Qingqing Zheng, Jianhong Wu, Chen Wang, Weiping Jia, Daniel Figeys, Ying Chang, Hu Zhou
Colorectal cancer (CRC) is one of the most common types of malignant tumor worldwide. Currently, although many researchers have been devoting themselves in CRC studies, the process of locating biomarkers for CRC early diagnosis and prognostic is still very slow. Using a centrifugal proteomic reactor-based proteomic analysis of minute amount of colonic biopsies by enteroscopy sampling, 2620 protein groups were quantified between cancer mucosa and adjacent normal colorectal mucosa. Of which, 403 protein groups were differentially expressed with statistic significance between cancer and normal tissues, including 195 up-regulated and 208 down-regulated proteins in cancer tissues...
August 5, 2016: Biochemical and Biophysical Research Communications
Yue Niu, Ling Zhang, Xing Bi, Shuai Yuan, Peng Chen
PURPOSE: To detect the expression of vitronectin (VTN) in the tissues and blood serum of prostate cancer (PCa) patients, and evaluate its clinical significance and to evaluate the significance of the combined assay of VTN and prostate specific antigens (PSA) in PCa diagnosis. MATERIALS AND METHODS: To detect the expression of VTN as a potential marker for PCa diagnosis and prognosis, immunohistochemistry was performed on the tissues of 32 patients with metastatic PCa (PCaM), 34 patients with PCa without metastasis (PCa), and 41 patients with benign prostatic hyperplasia (BPH)...
January 2016: Urology Journal
Robert C Amland, Jason J Lyons, Tracy L Greene, James M Haley
OBJECTIVE: To examine the diagnostic accuracy of a two-stage clinical decision support system for early recognition and stratification of patients with sepsis. DESIGN: Observational cohort study employing a two-stage sepsis clinical decision support to recognise and stratify patients with sepsis. The stage one component was comprised of a cloud-based clinical decision support with 24/7 surveillance to detect patients at risk of sepsis. The cloud-based clinical decision support delivered notifications to the patients' designated nurse, who then electronically contacted a provider...
October 2015: JRSM Open
Manuela Jaindl, Gerhard Oberleitner, Georg Endler, Christiane Thallinger, Florian M Kovar
BACKGROUND: Bite wounds are among the commonest types of trauma to which man is the subject. They account for 5 % of the total traumatic wounds evaluated in the emergency department (ED) and approximately 1 % of all the ED visits. Early estimation of infection risk, adequate antibiotic therapy and if indicated surgical treatment are the cornerstones of successful cure of bite wounds. METHODS: A total of 5248 consecutive trauma patients were collected prospectively and analysed retrospectively over a period of 15 years in this study at a level I trauma centre, Department of Trauma Surgery, Medical University of Vienna, Austria...
May 2016: Wiener Klinische Wochenschrift
Rebecca Wyatt, Alistair J K Williams
Type 1 diabetes (T1D) is a chronic inflammatory disease, caused by the immune mediated destruction of insulin-producing β-cells in the islets of the pancreas (Ziegler and Nepom, Immunity 32(4):468-478, 2010). Semiquantitative assays with high specificity and sensitivity for T1D are now available to detect antibodies to the four major islet autoantigens: glutamate decarboxylase (GADA) (Baekkeskov et al., Nature 347(6289):151-156, 1990), the protein tyrosine phosphatase-like proteins IA-2 (IA-2A) and IA-2β (Notkins et al...
2016: Methods in Molecular Biology
Marc-Antoine Allard, Antonio Sa Cunha, Brice Gayet, René Adam, Diane Goere, Philippe Bachellier, Daniel Azoulay, Ahmet Ayav, Francis Navarro, Patrick Pessaux
OBJECTIVE: To compare early and long-term outcomes in patients undergoing resection for colorectal liver metastases (CLM) by either a laparoscopic (LA) or an open (OA) approach. BACKGROUND: The LA is still a matter of debate regarding the surgical management of CLM. METHODS: Data of all patients from 32 French surgical centers who underwent liver resection for CLM from January 2006 to December 2013 were collected. Aiming to obtain 2 well-balanced cohorts for available variables influencing early outcome and survival, the LA group was matched 1:1 with the OA group by using a propensity score (PS)-based method...
November 2015: Annals of Surgery
Micaela M Esquivel, George Molina, Tarsicio Uribe-Leitz, Stuart R Lipsitz, John Rose, Stephen W Bickler, Atul A Gawande, Alex B Haynes, Thomas G Weiser
BACKGROUND: The global volume of surgery in 2012 is estimated at 312·9 million operations per year, but rates of surgery vary substantially. Maternal health advocates proposed minimum caesarean delivery rates for benchmarking and to improve perinatal outcomes; however, this has not been done for surgery because the association between rates of surgical care provision as a whole and population health outcomes have not been well described. We use available data to estimate minimum rates of surgery that are associated with important health indicators...
April 27, 2015: Lancet
Jocelyn Alexandria Carter, Laura S Carr, Jacqueline Collins, Joanne Doyle Petrongolo, Kathryn Hall, Jane Murray, Jessica Smith, Lee Ann Tata
SETTING: Massachusetts General Hospital embarked on a 4-year project to reduce readmissions in a high volume general medicine unit (November 2009 to September 2013). OBJECTIVE: To reduce 30-day readmissions to 10% through improved care coordination. DESIGN: As a before-after study, a total of 7586 patients admitted to the medicine unit during the intervention period included 2620 inpatients meeting high risk for readmission criteria. Of those, 2620 patients received nursing interventions and 539 patients received pharmacy interventions...
July 2015: BMJ Innovations
Masami Hamada, Yoshinari Yasuda, Sawako Kato, Hiroki Arafuka, Motomitsu Goto, Mutsuharu Hayashi, Etsuko Kajita, Shoichi Maruyama
BACKGROUND: Poor physical ability and skeletal muscle wasting are common in chronic kidney disease (CKD) patients, who may experience a decline in daily activity and, in turn, increased mortality. The purpose of this study was to evaluate the effectiveness and safety of modest exercise in patients with stable CKD. METHODS: Forty-seven CKD patients were enrolled in a 6-month group program for aerobic and resistance exercise by self-training. Parameters of physical function and clinical laboratory markers, including renal function, were measured...
April 2016: Clinical and Experimental Nephrology
Iris M van Hagen, Jolien W Roos-Hesselink, Titia P E Ruys, Waltraut M Merz, Sorel Goland, Harald Gabriel, Malgorzata Lelonek, Olga Trojnarska, Wael Abdulrahman Al Mahmeed, Hajnalka Olga Balint, Zeinab Ashour, Helmut Baumgartner, Eric Boersma, Mark R Johnson, Roger Hall
BACKGROUND: Pregnant women with a mechanical heart valve (MHV) are at a heightened risk of a thrombotic event, and their absolute need for adequate anticoagulation puts them at considerable risk of bleeding and, with some anticoagulants, fetotoxicity. METHODS AND RESULTS: Within the prospective, observational, contemporary, worldwide Registry of Pregnancy and Cardiac disease (ROPAC), we describe the pregnancy outcome of 212 patients with an MHV. We compare them with 134 patients with a tissue heart valve and 2620 other patients without a prosthetic valve...
July 14, 2015: Circulation
Long Yan, Feng Xie, Jiongjiong Lu, Qingqiang Ni, Changying Shi, Caixi Tang, Jiamei Yang
BACKGROUND: Ascites is the most common complication of cirrhosis. It may lead to the consequence of poor prognosis and the deterioration of quality of life. Asopressin V2 receptor antagonists is a kind of vaptans, and it has been proved to be effective in hyponatremia patients. We conducted a meta-analysis about treatment of vaptans in cirrhosis patients with ascites. METHODS: Following our selection criteria, we collected a total of 14 studies containing 16 randomized controlled trials (2620 patients) from a series of database about the treatment with vaptans for cirrhosis with ascites patients...
2015: BMC Gastroenterology
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