keyword
https://read.qxmd.com/read/38350223/placental-energy-metabolism-evidence-for-a-placental-maternal-lactate-ketone-trade-in-the-human
#21
JOURNAL ARTICLE
Tore Henriksen, Muhammad U Sajjad, Guttorm Haugen, Trond M Michelsen
INTRODUCTION: Glucose from placenta is the predominant energy source for the fetus. Individual placentas exhibit a range of glucose handling from apparent net production to high consumption, presumably reflecting an ability of placenta to secure both own and fetal energy needs. A dependency of placenta on glucose as the main energy source could impede fetal supply. Placenta seems to release lactate to maternal side implying loss of energy. Whether placenta takes up ketones is unclear...
February 5, 2024: Placenta
https://read.qxmd.com/read/38325239/assessment-of-the-cerebroplacental-ratio-and-uterine-arteries-in-low-risk-pregnancies-in-early-labour-for-the-prediction-of-obstetric-and-neonatal-outcomes
#22
JOURNAL ARTICLE
Andrea Dall'Asta, Tiziana Frusca, Giuseppe Rizzo, Ruben Ramirez Zegarra, Christoph Lees, Francesc Figueras, Tullio Ghi
BACKGROUND: The evidence-based management of human labor includes the antepartum identification of patients at risk for intrapartum hypoxia. However, available evidence has shown that most of the hypoxic-related complications occur among pregnancies classified at low-risk for intrapartum hypoxia, thus suggesting that the current strategy to identify the pregnancies at risk for intrapartum fetal hypoxia has limited accuracy. OBJECTIVE: To evaluate the role of the combined assessment of the cerebroplacental ratio (CPR) and uterine arteries (UtA) Doppler in the prediction of obstetric intervention (OI) for suspected intrapartum fetal compromise (IFC) within a cohort of low-risk singleton term pregnancies in early labor...
February 5, 2024: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38323934/maternal-supplementation-of-curcumin-olive-oil-nanocomposite-improves-uteroplacental-blood-flow-placental-growth-and-antioxidant-capacity-in-goats
#23
JOURNAL ARTICLE
Hossam R El-Sherbiny, Haney Samir, Fady Sayed Youssef, Gehad G Mohamed, Sameh H Ismail, Khaled H El-Shahat, Amal M Aboelmaaty, Karima F Mahrous, Khalid M Al Syaad, Ahmed Ezzat Ahmed, Fatimah A Al-Saeed, Alduwish Manal Abduallah, Elshymaa A Abdelnaby
This experiment was designed to investigate the impact of curcumin-olive oil nanocomposite (CONC) supplementation on uteroplacental hemodynamics and ultrasonographic measurements as well as maternal oxidative status in midgestating goats. Twelve synchronized pregnant goats (85.58 ± 1.08 days of gestation; mean ± SD) were uniformly assigned to two groups (n = 6/group); the first group received daily oral supplementation of CONC (3 mg/kg body weight; nanocurcumin [NC] group) for 32 days, and the second group was offered physiological saline (control) following the NC group timeline...
February 7, 2024: Journal of Animal Physiology and Animal Nutrition
https://read.qxmd.com/read/38318428/non-invasive-evaluation-of-endometrial-microvessels-via-in-vivo-intrauterine-photoacoustic-endoscopy
#24
JOURNAL ARTICLE
Qingrong Xia, Shengmiao Lv, Haoxing Xu, Xiatian Wang, Zhihua Xie, Riqiang Lin, Jinke Zhang, Chengyou Shu, Zhiyi Chen, Xiaojing Gong
The endometrium microvessel system, responsible for supplying oxygen and nutrients to the embryo, holds significant importance in evaluating endometrial receptivity (ER). Visualizing this system directly can significantly enhance ER evaluation. Currently, clinical methods like Narrow-band hysteroscopy and Color Doppler ultrasound are commonly used for uterine blood vessel examination, but they have limitations in depth or resolution. Endoscopic Photoacoustic Imaging (PAE) has proven effective in visualizing microvessels in the digestive tract, while its adaptation to uterine imaging faces challenges due to the uterus's unique physiological characteristics...
April 2024: Photoacoustics
https://read.qxmd.com/read/38295969/ultrasound-and-magnetic-resonance-imaging-based-investigation-of-the-role-of-perfusion-and-oxygen-availability-in-menstrual-pain
#25
JOURNAL ARTICLE
Richard H Cockrum, Frank F Tu, Ola Kierzkowska, Nondas Leloudas, Prasad V Pottumarthi, Kevin M Hellman
BACKGROUND: The mechanisms responsible for menstrual pain are poorly understood. However, dynamic, noninvasive pelvic imaging of menstrual pain sufferers could aid in identifying therapeutic targets and testing novel treatments. OBJECTIVE: To study the mechanisms responsible for menstrual pain, we analyzed ultrasonographic and complementary functional magnetic resonance imaging parameters in dysmenorrhea sufferers and pain-free controls under multiple conditions...
January 29, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38292508/comparison-of-doppler-ultrasound-indices-of-uterine-artery-and-sub-endometrial-blood-supply-in-frozen-embryo-transfer-with-and-without-repeated-implantation-failure-a-cross-sectional-study
#26
JOURNAL ARTICLE
Fatemeh Bayati, Maryam Eftekhar, Nahid Homayoon, Haniyeh Fatehi
Background: Uterine blood supply has been identified as a potential factor in implantation failure. Objective: This study aimed to investigate Doppler indices in the uterine artery, including vascular flow and resistance, as well as the amount of sub-endometrial blood supply in women with a history of repeated implantation failure (RIF) compared to the non-RIF group. Materials and Methods: This cross-sectional study was conducted with 139 women candidates for frozen embryo transfer in Yazd Reproductive Sciences Institute, Yazd, Iran from February to July 2023...
November 2023: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://read.qxmd.com/read/38269478/serum-mirna-combined-with-transvaginal-color-doppler-ultrasound-diagnosis-clinical-research-on-cervical-cancer
#27
JOURNAL ARTICLE
Yan Wang, Jun Yang, Yin Wang
OBJECTIVES: To explore clinical value of miRNA-18a, miRNA-130a, miRNA-92a combined with transvaginal color Doppler ultrasound (TVCDS) in diagnosis of cervical cancer (CC). METHODS: Hundred patients with pathologically confirmed CC (CC group), 100 patients with cervical epithelial neoplasia (disease group), and 100 patients with benign uterine lesions (control group) were selected. TVCDS was performed, and the levels of serum miRNA-18a, miRNA-130a, and miRNA-92a were detected...
January 25, 2024: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://read.qxmd.com/read/38268215/renal-biomarkers-clinical-parameters-and-renal-doppler-velocimetry-in-bitches-with-cystic-endometrial-hyperplasia-pyometra-complex
#28
JOURNAL ARTICLE
Leticia Amanda Dos Santos Silva, Luiz Guilherme Corsi Trautwein, Myrian Megumy Tsunokawa Hidalgo, Ana Beatriz Marques de Almeida, Julia Rodrigues Greghi, Natália Ribeiro Sambatti, Vinícius Wagner Silva, Karina Keller Marques da Costa Flaiban, Maria Isabel Mello Martins
Cystic endometrial hyperplasia (CEH)-pyometra complex is the most common uterine infection in adult and elderly bitches and can cause renal dysfunction. The aim of this study was to measure and compare urinary creatinine, urea, symmetric dimethylarginine (SDMA), urinary protein-creatinine ratio (UPC), measurement of systolic blood pressure (SBP), and Doppler velocimetry of renal arteries in patients with CEH-pyometra complex before and after an average of 6 months of treatment, evaluating the possibility of the changes persisting...
January 2024: Reproduction in Domestic Animals
https://read.qxmd.com/read/38262266/effect-of-pyometra-on-vascularity-alterations-oxidative-stress-histopathology-and-inflammatory-molecules-in-feline
#29
JOURNAL ARTICLE
Elshymaa A Abdelnaby, Abdulrhman K Alhaider, Ibrahim M Ghoneim, Noha Y Salem, Eman S Ramadan, Haithem A Farghali, Marwa S Khattab, Naglaa A AbdElKader, Ibrahim A Emam
This study aimed to investigate blood flow, hemodynamical features by Doppler ultrasound, the oxidative stress biomarkers from serum samples, and histopathology from uterine tissue, in healthy queens and queens with pyometra. Twenty queens were categorized into two groups, according to signs, history, and ultrasound findings, as pyometra and control healthy queens. Doppler ultrasonography, total antioxidant capacity (TAC), malondialdehyde (MDA), albumin, bacteriological isolation, histopathology, and immunohistochemistry of tumor necrosis factor-alpha (TNF-α) and nuclear factor kappa B (NF-κB) P65 were performed...
January 22, 2024: Reproductive Biology
https://read.qxmd.com/read/38244830/first-trimester-risk-of-preeclampsia-and-rate-of-spontaneous-birth-in-patients-without-preeclampsia
#30
JOURNAL ARTICLE
Paolo I Cavoretto, Antonio Farina, Noemi Salmeri, Argyro Syngelaki, Min Yi Tan, Kypros H Nicolaides
BACKGROUND: First-trimester screening for preeclampsia (PE), by a combination of maternal risk factors and mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI) and placental growth factor (PlGF), as proposed by the Fetal Medicine Foundation (FMF) provides effective prediction of preterm PE. Placental dysfunction is a potential precursor of spontaneous birth. OBJECTIVE: The objective of this study is to examine whether the estimated risk of PE is associated with the gestational age at onset of spontaneous delivery in the absence of PE...
January 18, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38226112/early-prediction-of-hypertensive-diseases-of-pregnancy-by-using-combined-screening-methods-in-a-rural-population
#31
JOURNAL ARTICLE
Ruhida Razzak, Poonam V Shivkumar
INTRODUCTION: The most frequent medical issue during pregnancy is hypertension, which can complicate up to 10% to 15% of pregnancies worldwide. An estimated 14% of all maternal fatalities worldwide are thought to be caused by hypertensive disease of pregnancy, one of the main causes of maternal and fetal morbidity and mortality. Despite the fact that maternal mortality is substantially lower in high-income countries than in low- and middle-income countries, hypertension is still one of the leading causes of maternal death globally...
December 2023: Curēus
https://read.qxmd.com/read/38218510/umbilical-portal-systemic-venous-shunt-and-fetal-growth-restriction-an-inquiry-from-a-prospective-study
#32
JOURNAL ARTICLE
Shelly Czeiger, Tal Weissbach, Keren Zloto, Ariella Wiener, Omer Nir, Abeer Massarwa, Boaz Weisz, Michal Fishel Bartal, Rakefet Yoeli Ulman, Yossi Bart, Reuven Achiron, Zvi Kivilevitch, Shali Mazaki-Tovi, Eran Kassif
BACKGROUND: The investigation of the fetal umbilical-portal venous system is based on the premise that congenital anomalies of this system may be related to adverse perinatal outcomes. Several retrospective small studies have reported a well-established association between umbilical-portal-systemic venous shunts and fetal growth restriction. However, the prevalence of portosystemic shunts in the fetal growth restricted population is yet to be determined. OBJECTIVES: The aims of this study were: 1...
January 11, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38217113/an-investigation-of-endometrial-vascularity-in-normally-menstruating-women-and-those-in-other-physiological-states-using-3d-ultrasound-imaging
#33
JOURNAL ARTICLE
Ammar Ahmed Khan, Aisha Al-Motawa, Najeeb Halabi, Badreldeen Ahmed, Jeremie Arash Rafii, Justin C Konje
OBJECTIVES: This study aimed to determine the normal vasculature indices of the endometrium and to correlate them with those in various physiological states. METHODS: Women undergoing ultrasound at the Feto-Maternal Center, Qatar in 2020-2021 as part of their gynecologic evaluation were enrolled into the study. They were divided into those with normal menses and no additional pathology, those following spontaneous miscarriage, postpartum and menopausal. Three-dimensional (3D) evaluation of the endometrial vasculature was done and the parameters quantified included vascularization index (VI), flow index (FI), vascularization flow index (VFI), endometrial thickness, endometrial volume and uterine volume...
January 12, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38199820/application-value-of-ultrasound-elastography-for-screening-of-early-pregnancy-cervical-insufficiency-a-retrospective-case-control-study
#34
JOURNAL ARTICLE
Hua Jiang, Zhang Bo
OBJECTIVE: This study aimed to investigate changes in the cervical strain rate (SR), cervical length (CL), and uterine artery blood flow parameters during early pregnancy in women with cervical insufficiency and evaluate the clinical efficacy of these markers for screening of cervical insufficiency in early pregnancy. METHODS: This retrospective study in 60 pregnant women with cervical insufficiency and 100 normal pregnant women was conducted between September 2021 and January 2023 and measured ultrasound parameters of the cervix during early pregnancy...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38182901/serum-fatty-acid-binding-protein-4-and-doppler-of-uterine-artery-ultrasound-in-the-first-trimester-for-the-prediction-of-preeclampsia
#35
JOURNAL ARTICLE
Chaiyawut Paiboonborirak, Vorapong Phupong
The objective of this study was to determine the predictive value of serum fatty acid binding protein 4 (FABP4) combined with Doppler of the uterine artery in singleton pregnancy at gestational age (GA) 11-13+6 weeks for prediction of preeclampsia. A prospective observational study included singleton pregnant women at GA 11-13+6 weeks and was conducted at the Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, between December 2020 and April 2022. Serum FABP4 levels and Doppler of the uterine artery were performed...
January 5, 2024: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://read.qxmd.com/read/38161858/postabortal-bleeding-a-diagnostic-dilemma-resolved-as-arteriovenous-malformation-and-successfully-managed-with-uterine-artery-embolization
#36
Shreya Agrawal, Apoorva Dave, Samarth Shukla
Uterine arteriovenous malformations (AVM) are rare and may be missed in routine clinical practice, often concealing their existence until dire consequences emerge. This potentially lethal condition can manifest abruptly, with torrential postabortal bleeding, as a grim reminder of its risky nature. Here, we present a rare case of para 1, living 1, abortion 2, initially subjected to dilatation and evacuation due to a missed abortion at a peripheral healthcare facility, subsequently developing torrential bleeding despite all the conservative measures...
November 2023: Curēus
https://read.qxmd.com/read/38145554/prenatal-prediction-of-adverse-outcome-using-different-charts-and-definitions-of-fetal-growth-restriction
#37
JOURNAL ARTICLE
M Mascherpa, C Pegoire, A Meroni, M Minopoli, B Thilaganathan, A Frick, A Bhide
OBJECTIVE: Fetal growth assessment by ultrasound aims to identify small babies that are at higher risk of perinatal morbidity and mortality. The current study explores if the association between suboptimal fetal growth and adverse perinatal outcome varies with different definitions of fetal growth restriction and weight charts/standards. METHODS: This was a retrospective cohort study of 17261 singleton non-anomalous pregnancies from 24+0 weeks' gestation at a tertiary referral hospital...
December 25, 2023: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38143695/uterine-artery-doppler-indices-as-predictor-of-adverse-fetal-outcome-in-hypertensive-disorders-of-pregnancy-an-observational-study
#38
JOURNAL ARTICLE
Sakshi Duragkar, Kalyani S Mahajan, Deepika Dewani
Background Hypertensive disorders of pregnancy (HDP) pose significant risks to maternal and fetal health. The utility of Doppler indices in predicting adverse fetal outcomes in HDP patients remains an area of active research. This observational study aimed to assess the correlation between abnormal uterine artery Doppler indices and adverse fetal outcomes in HDP patients. Methods Over a two-year period, we enrolled 138 pregnant women with HDP beyond 28 weeks of gestation and singleton pregnancies. Detailed clinical assessments, laboratory investigations, and Doppler studies of the uterine artery were conducted...
November 2023: Curēus
https://read.qxmd.com/read/38137327/uterine-arteries-resistance-in-pregnant-women-with-gestational-diabetes-mellitus-diabetes-mellitus-type-1-diabetes-mellitus-type-2-and-uncomplicated-pregnancies
#39
JOURNAL ARTICLE
Christos Chatzakis, Makarios Eleftheriades, Eleftheria Demertzidou, Anna Eleftheriades, Nikolaos Koletsos, Lazaros Lavasidis, Athanasios Zikopoulos, Konstantinos Dinas, Alexandros Sotiriadis
BACKGROUND: The examination of the uterine arteries using Doppler in the first trimester of pregnancy serves as a valuable tool for evaluating the uteroplacental circulation. Diabetes mellitus is associated with altered placental implantation and pregnancy-related pathologies, such as preeclampsia. The aim of this study was to compare the uterine arteries' pulsatility indices (UtA PI) in women with diabetes mellitus type 1 (DM1), diabetes mellitus type 2 (DM2), gestational diabetes mellitus (GDM), and uncomplicated pregnancies...
November 21, 2023: Biomedicines
https://read.qxmd.com/read/38126224/placenta-acrreta-spectrum-first-trimester-2d-and-3d-ultrasound-and-magnetic-resonance-imaging-findings
#40
JOURNAL ARTICLE
Edward Araujo Júnior, João Victor Jacomele Caldas, Sue Yasaki Sun, Pedro Teixeira Castro, Jurandir Piassi Passos, Heron Werner
BACKGROUND: The term placenta accreta spectrum (PAS) is commonly used to describe abnormal trophoblastic invasion of the myometrium, serosa, or organs adjacent to the uterus. It is of great obstetric importance because of its high morbidity, risk of hemorrhage, admission to the intensive care unit, risk of hysterectomy, and high risk of iatrogenic pelvic lesions and even death. These risks are minimized when prenatal diagnosis is performed. Prenatal diagnosis of PAS is based on imaging findings suggestive of abnormal and pathologically adherent placentation, including placental lacunae (intraplacental sonolucent spaces), disruption of the bladder-uterine serosa interface, turbulent flow on color Doppler, and bridging vessels...
December 21, 2023: Journal of Clinical Ultrasound: JCU
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