keyword
MENU ▼
Read by QxMD icon Read
search

Stephanie L. Martin

keyword
https://www.readbyqxmd.com/read/29781669/trajectories-of-irregular-word-reading-ability-as-a-proxy-for-premorbid-intelligence-in-alzheimer-s-disease-mild-cognitive-impairment-and-healthy-aging-a-longitudinal-study
#1
Michael Weinborn, Romola S Bucks, Hamid R Sohrabi, Stephanie R Rainey-Smith, Belinda M Brown, Samantha L Gardener, Aleksandra Gozt, Daniel Christensen, Greg Savage, Simon M Laws, Kevin Taddei, Paul Maruff, Joanne S Robertson, Kathryn A Ellis, David Ames, Colin L Masters, Christopher C Rowe, Ralph N Martins
The ability to read irregularly spelled words is commonly used to estimate premorbid intelligence, as this ability has been thought to be resistant to early effects of neurodegenerative disorders. However, studies evaluating decline of this skill in Alzheimer's disease (AD) have produced conflicting results. Irregular word reading was assessed three times over 36 months in a large (N = 995) sample, including healthy control, AD, and Mild Cognitive Impairment (MCI) groups. At baseline, MCI and AD groups read correctly an average of 3...
May 21, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29778853/natural-history-of-diabetic-coronary-atherosclerosis-by-quantitative-measurement-of-serial-coronary-computed-tomographic-angiography-results-of-the-paradigm-study-progression-of-atherosclerotic-plaque-determined-by-computed-tomographic-angiography-imaging
#2
Ung Kim, Jonathon A Leipsic, Stephanie L Sellers, Michael Shao, Philipp Blanke, Martin Hadamitzky, Yong-Jin Kim, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J Budoff, Ilan Gottlieb, Byoung Kwon Lee, Eun Ju Chun, Filippo Cademartiri, Erica Maffei, Hugo Marques, Sanghoon Shin, Jung Hyun Choi, Renu Virmani, Habib Samady, Peter H Stone, Daniel S Berman, Jagat Narula, Leslee J Shaw, Jeroen J Bax, James K Min, Hyuk-Jae Chang
OBJECTIVES: This study aimed to determine the rate and extent of plaque progression (PP), changes in plaque features, and clinical predictors of PP in patients with diabetes mellitus (DM). BACKGROUND: The natural history of coronary PP in patients with DM is not well established. METHODS: A total of 1,602 patients (age 61.3 ± 9.0 years; 60.3% men; median scan interval 3.8 years) who underwent serial coronary computed tomography angiography over a period of at least 24 months were enrolled and analyzed from the PARADIGM (Progression of Atherosclerotic Plaque Determined by Computed Tomographic Angiography Imaging) trial...
May 11, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29758940/self-reported-physical-activity-is-associated-with-tau-burden-measured-by-positron-emission-tomography
#3
Belinda M Brown, Stephanie R Rainey-Smith, Vincent Dore, Jeremiah J Peiffer, Samantha C Burnham, Simon M Laws, Kevin Taddei, David Ames, Colin L Masters, Christopher C Rowe, Ralph N Martins, Victor L Villemagne
Numerous animal studies have reported exercise reduces the accumulation of Alzheimer's disease pathology, including amyloid-β (Aβ) and tau. Furthermore, we previously reported a relationship between higher levels of physical activity (PA) and lower brain Aβ burden in a human population. The recent advent of tau positron emission tomography (PET) tracers enables us to extend our investigations into the evaluation of the relationship between PA and brain tau burden. Utilizing data from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study, we have examined the cross-sectional relationship between habitual PA and PET-quantified tau burden...
May 11, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29756234/inhaling-xenon-ameliorates-l-dopa-induced-dyskinesia-in-experimental-parkinsonism
#4
Jérôme Baufreton, Tomislav Milekovic, Qin Li, Steve McGuire, Eduardo Martin Moraud, Grégory Porras, Shiqi Sun, Wai Kin D Ko, Marine Chazalon, Stéphanie Morin, Elisabeth Normand, Géraldine Farjot, Aude Milet, Jan Pype, Elsa Pioli, Gregoire Courtine, Baptiste Bessière, Erwan Bezard
Parkinson's disease motor symptoms are treated with levodopa, but long-term treatment leads to disabling dyskinesia. Altered synaptic transmission and maladaptive plasticity of corticostriatal glutamatergic projections play a critical role in the pathophysiology of dyskinesia. Because the noble gas xenon inhibits excitatory glutamatergic signaling, primarily through allosteric antagonism of the N-methyl-d-aspartate receptors, we aimed to test its putative antidyskinetic capabilities. We first studied the direct effect of xenon gas exposure on corticostriatal plasticity in a murine model of levodopa-induced dyskinesia We then studied the impact of xenon inhalation on behavioral dyskinetic manifestations in the gold-standard rat and primate models of PD and levodopa-induced dyskinesia...
May 14, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29746225/clinical-radiologic-pathologic-and-molecular-characteristics-of-long-term-survivors-of-diffuse-intrinsic-pontine-glioma-dipg-a-collaborative-report-from-the-international-and-european-society-for-pediatric-oncology-dipg-registries
#5
Lindsey M Hoffman, Sophie E M Veldhuijzen van Zanten, Niclas Colditz, Joshua Baugh, Brooklyn Chaney, Marion Hoffmann, Adam Lane, Christine Fuller, Lili Miles, Cynthia Hawkins, Ute Bartels, Eric Bouffet, Stewart Goldman, Sarah Leary, Nicholas K Foreman, Roger Packer, Katherine E Warren, Alberto Broniscer, Mark W Kieran, Jane Minturn, Melanie Comito, Emmett Broxson, Chie-Schin Shih, Soumen Khatua, Murali Chintagumpala, Anne Sophie Carret, Nancy Yanez Escorza, Timothy Hassall, David S Ziegler, Nicholas Gottardo, Hetal Dholaria, Renee Doughman, Martin Benesch, Rachid Drissi, Javad Nazarian, Nada Jabado, Nathalie Boddaert, Pascale Varlet, Géraldine Giraud, David Castel, Stephanie Puget, Chris Jones, Esther Hulleman, Piergiorgio Modena, Marzia Giagnacovo, Manila Antonelli, Torsten Pietsch, Gerrit H Gielen, David T W Jones, Dominik Sturm, Stefan M Pfister, Nicolas U Gerber, Michael A Grotzer, Elke Pfaff, André O von Bueren, Darren Hargrave, Guirish A Solanki, Filip Jadrijevic Cvrlje, Gertjan J L Kaspers, William P Vandertop, Jacques Grill, Simon Bailey, Veronica Biassoni, Maura Massimino, Raphaël Calmon, Esther Sanchez, Brigitte Bison, Monika Warmuth-Metz, James Leach, Blaise Jones, Dannis G van Vuurden, Christof M Kramm, Maryam Fouladi
Purpose Diffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median survival of < 1 year. The International and European Society for Pediatric Oncology DIPG Registries collaborated to compare clinical, radiologic, and histomolecular characteristics between short-term survivors (STSs) and long-term survivors (LTSs). Materials and Methods Data abstracted from registry databases included patients from North America, Australia, Germany, Austria, Switzerland, the Netherlands, Italy, France, the United Kingdom, and Croatia...
May 10, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29746190/criterion-a-of-the-ampd-in-hitop
#6
Thomas A Widiger, Bo Bach, Michael Chmielewski, Lee Anna Clark, Colin DeYoung, Christopher J Hopwood, Roman Kotov, Robert F Krueger, Joshua D Miller, Leslie C Morey, Stephanie N Mullins-Sweatt, Christopher J Patrick, Aaron L Pincus, Douglas B Samuel, Martin Sellbom, Susan C South, Jennifer L Tackett, David Watson, Mark H Waugh, Aidan G C Wright, Johannes Zimmermann, R Michael Bagby, David C Cicero, Christopher C Conway, Barbara De Clercq, Anna R Docherty, Nicholas R Eaton, Kelsie T Forbush, J D Haltigan, Masha Y Ivanova, Robert D Latzman, Donald R Lynam, Kristian E Markon, Ulrich Reininghaus, Katherine M Thomas
The categorical model of personality disorder classification in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (5th ed. [DSM-5]; American Psychiatric Association, 2013 ) is highly and fundamentally problematic. Proposed for DSM-5 and provided within Section III (for Emerging Measures and Models) was the Alternative Model of Personality Disorder (AMPD) classification, consisting of Criterion A (self-interpersonal deficits) and Criterion B (maladaptive personality traits)...
May 10, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29722093/geophagic-earths-consumed-by-women-in-western-kenya-contain-dangerous-levels-of-lead-arsenic-and-iron
#7
Joshua D Miller, Shalean M Collins, Moshood Omotayo, Stephanie L Martin, Katherine L Dickin, Sera L Young
OBJECTIVES: Geophagy is commonly reported by pregnant women and children, yet its causes and consequences remain poorly understood. Therefore, we sought to determine if geophagy could contribute micronutrients and/or be a source of heavy metal exposure by examining the elemental composition of earths consumed in Kakamega, Kenya. METHODS: Ten samples of earths commonly consumed during pregnancy were collected by study enumerators and analyzed using inductively coupled plasma-atomic emission spectroscopy...
May 3, 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29713129/nonalcoholic-steatohepatitis-severity-is-defined-by-a-failure-in-compensatory-antioxidant-capacity-in-the-setting-of-mitochondrial-dysfunction
#8
Michelle L Boland, Stephanie Oldham, Brandon B Boland, Sarah Will, Jean-Martin Lapointe, Silvia Guionaud, Christopher J Rhodes, James L Trevaskis
AIM: To comprehensively evaluate mitochondrial (dys) function in preclinical models of nonalcoholic steatohepatitis (NASH). METHODS: We utilized two readily available mouse models of nonalcoholic fatty liver disease (NAFLD) with or without progressive fibrosis: Lepob /Lepob ( ob/ob ) and FATZO mice on high trans -fat, high fructose and high cholesterol (AMLN) diet. Presence of NASH was assessed using immunohistochemical and pathological techniques, and gene expression profiling...
April 28, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29700475/genome-wide-association-analyses-identify-44-risk-variants-and-refine-the-genetic-architecture-of-major-depression
#9
Naomi R Wray, Stephan Ripke, Manuel Mattheisen, Maciej Trzaskowski, Enda M Byrne, Abdel Abdellaoui, Mark J Adams, Esben Agerbo, Tracy M Air, Till M F Andlauer, Silviu-Alin Bacanu, Marie Bækvad-Hansen, Aartjan F T Beekman, Tim B Bigdeli, Elisabeth B Binder, Douglas R H Blackwood, Julien Bryois, Henriette N Buttenschøn, Jonas Bybjerg-Grauholm, Na Cai, Enrique Castelao, Jane Hvarregaard Christensen, Toni-Kim Clarke, Jonathan I R Coleman, Lucía Colodro-Conde, Baptiste Couvy-Duchesne, Nick Craddock, Gregory E Crawford, Cheynna A Crowley, Hassan S Dashti, Gail Davies, Ian J Deary, Franziska Degenhardt, Eske M Derks, Nese Direk, Conor V Dolan, Erin C Dunn, Thalia C Eley, Nicholas Eriksson, Valentina Escott-Price, Farnush Hassan Farhadi Kiadeh, Hilary K Finucane, Andreas J Forstner, Josef Frank, Héléna A Gaspar, Michael Gill, Paola Giusti-Rodríguez, Fernando S Goes, Scott D Gordon, Jakob Grove, Lynsey S Hall, Eilis Hannon, Christine Søholm Hansen, Thomas F Hansen, Stefan Herms, Ian B Hickie, Per Hoffmann, Georg Homuth, Carsten Horn, Jouke-Jan Hottenga, David M Hougaard, Ming Hu, Craig L Hyde, Marcus Ising, Rick Jansen, Fulai Jin, Eric Jorgenson, James A Knowles, Isaac S Kohane, Julia Kraft, Warren W Kretzschmar, Jesper Krogh, Zoltán Kutalik, Jacqueline M Lane, Yihan Li, Yun Li, Penelope A Lind, Xiaoxiao Liu, Leina Lu, Donald J MacIntyre, Dean F MacKinnon, Robert M Maier, Wolfgang Maier, Jonathan Marchini, Hamdi Mbarek, Patrick McGrath, Peter McGuffin, Sarah E Medland, Divya Mehta, Christel M Middeldorp, Evelin Mihailov, Yuri Milaneschi, Lili Milani, Jonathan Mill, Francis M Mondimore, Grant W Montgomery, Sara Mostafavi, Niamh Mullins, Matthias Nauck, Bernard Ng, Michel G Nivard, Dale R Nyholt, Paul F O'Reilly, Hogni Oskarsson, Michael J Owen, Jodie N Painter, Carsten Bøcker Pedersen, Marianne Giørtz Pedersen, Roseann E Peterson, Erik Pettersson, Wouter J Peyrot, Giorgio Pistis, Danielle Posthuma, Shaun M Purcell, Jorge A Quiroz, Per Qvist, John P Rice, Brien P Riley, Margarita Rivera, Saira Saeed Mirza, Richa Saxena, Robert Schoevers, Eva C Schulte, Ling Shen, Jianxin Shi, Stanley I Shyn, Engilbert Sigurdsson, Grant B C Sinnamon, Johannes H Smit, Daniel J Smith, Hreinn Stefansson, Stacy Steinberg, Craig A Stockmeier, Fabian Streit, Jana Strohmaier, Katherine E Tansey, Henning Teismann, Alexander Teumer, Wesley Thompson, Pippa A Thomson, Thorgeir E Thorgeirsson, Chao Tian, Matthew Traylor, Jens Treutlein, Vassily Trubetskoy, André G Uitterlinden, Daniel Umbricht, Sandra Van der Auwera, Albert M van Hemert, Alexander Viktorin, Peter M Visscher, Yunpeng Wang, Bradley T Webb, Shantel Marie Weinsheimer, Jürgen Wellmann, Gonneke Willemsen, Stephanie H Witt, Yang Wu, Hualin S Xi, Jian Yang, Futao Zhang, Volker Arolt, Bernhard T Baune, Klaus Berger, Dorret I Boomsma, Sven Cichon, Udo Dannlowski, E C J de Geus, J Raymond DePaulo, Enrico Domenici, Katharina Domschke, Tõnu Esko, Hans J Grabe, Steven P Hamilton, Caroline Hayward, Andrew C Heath, David A Hinds, Kenneth S Kendler, Stefan Kloiber, Glyn Lewis, Qingqin S Li, Susanne Lucae, Pamela F A Madden, Patrik K Magnusson, Nicholas G Martin, Andrew M McIntosh, Andres Metspalu, Ole Mors, Preben Bo Mortensen, Bertram Müller-Myhsok, Merete Nordentoft, Markus M Nöthen, Michael C O'Donovan, Sara A Paciga, Nancy L Pedersen, Brenda W J H Penninx, Roy H Perlis, David J Porteous, James B Potash, Martin Preisig, Marcella Rietschel, Catherine Schaefer, Thomas G Schulze, Jordan W Smoller, Kari Stefansson, Henning Tiemeier, Rudolf Uher, Henry Völzke, Myrna M Weissman, Thomas Werge, Ashley R Winslow, Cathryn M Lewis, Douglas F Levinson, Gerome Breen, Anders D Børglum, Patrick F Sullivan
Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide association meta-analysis based in 135,458 cases and 344,901 controls and identified 44 independent and significant loci. The genetic findings were associated with clinical features of major depression and implicated brain regions exhibiting anatomical differences in cases. Targets of antidepressant medications and genes involved in gene splicing were enriched for smaller association signal...
April 26, 2018: Nature Genetics
https://www.readbyqxmd.com/read/29690278/remarkable-fly-diptera-diversity-in-a-patch-of-costa-rican-cloud-forest-why-inventory-is-a-vital-science
#10
Art Borkent, Brian V Brown, Peter H Adler, Dalton de Souza Amorim, Kevin Barber, Daniel Bickel, Stephanie Boucher, Scott E Brooks, John Burger, Z L Burington, Renato S Capellari, Daniel N R Costa, Jeffrey M Cumming, Greg Curler, Carl W Dick, J H Epler, Eric Fisher, Stephen D Gaimari, Jon Gelhaus, David A Grimaldi, John Hash, Martin Hauser, Heikki Hippa, Sergio IbÁÑez-Bernal, Mathias Jaschhof, Elena P Kameneva, Peter H Kerr, Valery Korneyev, Cheslavo A Korytkowski, Giar-Ann Kung, Gunnar Mikalsen Kvifte, Owen Lonsdale, Stephen A Marshall, Wayne N Mathis, Verner Michelsen, Stefan Naglis, Allen L Norrbom, Steven Paiero, Thomas Pape, Alessandre Pereira-Colavite, Marc Pollet, Sabrina Rochefort, Alessandra Rung, Justin B Runyon, Jade Savage, Vera C Silva, Bradley J Sinclair, Jeffrey H Skevington, John O Iii Stireman, John Swann, Pekka Vilkamaa, Terry Wheeler, Terry Whitworth, Maria Wong, D Monty Wood, Norman Woodley, Tiffany Yau, Thomas J Zavortink, Manuel A Zumbado
Study of all flies (Diptera) collected for one year from a four-hectare (150 x 266 meter) patch of cloud forest at 1,600 meters above sea level at Zurquí de Moravia, San José Province, Costa Rica (hereafter referred to as Zurquí), revealed an astounding 4,332 species. This amounts to more than half the number of named species of flies for all of Central America. Specimens were collected with two Malaise traps running continuously and with a wide array of supplementary collecting methods for three days of each month...
March 27, 2018: Zootaxa
https://www.readbyqxmd.com/read/29674744/author-correction-genome-wide-analysis-of-multi-and-extensively-drug-resistant-mycobacterium-tuberculosis
#11
Francesc Coll, Jody Phelan, Grant A Hill-Cawthorne, Mridul B Nair, Kim Mallard, Shahjahan Ali, Abdallah M Abdallah, Saad Alghamdi, Mona Alsomali, Abdallah O Ahmed, Stephanie Portelli, Yaa Oppong, Adriana Alves, Theolis Barbosa Bessa, Susana Campino, Maxine Caws, Anirvan Chatterjee, Amelia C Crampin, Keertan Dheda, Nicholas Furnham, Judith R Glynn, Louis Grandjean, Dang Minh Ha, Rumina Hasan, Zahra Hasan, Martin L Hibberd, Moses Joloba, Edward C Jones-López, Tomoshige Matsumoto, Anabela Miranda, David J Moore, Nora Mocillo, Stefan Panaiotov, Julian Parkhill, Carlos Penha, João Perdigão, Isabel Portugal, Zineb Rchiad, Jaime Robledo, Patricia Sheen, Nashwa Talaat Shesha, Frik A Sirgel, Christophe Sola, Erivelton Oliveira Sousa, Elizabeth M Streicher, Paul Van Helden, Miguel Viveiros, Robert M Warren, Ruth McNerney, Arnab Pain, Taane G Clark
In the version of this article initially published, the URL listed for TubercuList was incorrect. The correct URL is https://mycobrowser.epfl.ch/. The error has been corrected in the HTML and PDF versions of the article.
April 19, 2018: Nature Genetics
https://www.readbyqxmd.com/read/29669892/wing-scale-ultrastructure-underlying-convergent-and-divergent-iridescent-colours-in-mimetic-heliconius-butterflies
#12
Andrew J Parnell, James E Bradford, Emma V Curran, Adam L Washington, Gracie Adams, Melanie N Brien, Stephanie L Burg, Carlos Morochz, J Patrick A Fairclough, Pete Vukusic, Simon J Martin, Scott Doak, Nicola J Nadeau
Iridescence is an optical phenomenon whereby colour changes with the illumination and viewing angle. It can be produced by thin film interference or diffraction. Iridescent optical structures are fairly common in nature, but relatively little is known about their production or evolution. Here we describe the structures responsible for producing blue-green iridescent colour in Heliconius butterflies. Overall the wing scale structures of iridescent and non-iridescent Heliconius species are very similar, both having longitudinal ridges joined by cross-ribs...
April 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29669811/linker-engineering-in-anti-tag-72-antibody-fragments-optimizes-biophysical-properties-serum-half-life-and-high-specificity-tumor-imaging
#13
Nicholas E Long, Brandon J Sullivan, Haiming Ding, Stephanie R Doll, Michael A Ryan, Charles L Hitchcock, Edward W Martin, Krishan Kumar, Michael F Tweedle, Thomas J Magliery
Antibody (Ab) fragments have great clinical potential as cancer therapeutics and diagnostics. Their small size allows for fast clearance from blood, low immunoreactivity, better tumor penetration, and simpler engineering and production. The smallest fragment derived from a full-length IgG that retains binding to its antigen, the single-chain variable fragment (scFV), is engineered by fusing the variable light and variable heavy domains with a peptide linker. Along with switching the domain orientation, altering the length and amino acid sequence of the linker can significantly affect scFV binding, stability, quaternary structure, and other biophysical properties...
April 18, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29659601/in-vitro-assessment-of-cytotoxic-activities-of-lachesis-muta-muta-snake-venom
#14
Stephanie Stransky, Fernanda Costal-Oliveira, Letícia Lopes-de-Souza, Clara Guerra-Duarte, Carlos Chávez-Olórtegui, Vania Maria Martin Braga
Envenomation by the bushmaster snake Lachesis muta muta is considered severe, characterized by local effects including necrosis, the main cause of permanent disability. However, cellular mechanisms related to cell death and tissue destruction, triggered by snake venoms, are poorly explored. The purpose of this study was to investigate the cytotoxic effect caused by L. m. muta venom in normal human keratinocytes and to identify the cellular processes involved in in cellulo envenomation. In order to investigate venom effect on different cell types, Alamar Blue assay was performed to quantify levels of cellular metabolism as a readout of cell viability...
April 16, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29656508/the-3-rd-world-conference-on-kisspeptin-kisspeptin-2017-brain-and-beyond-unresolved-questions-challenges-and-future-directions-for-the-field
#15
REVIEW
Michael N Lehman, Lique M Coolen, Robert A Steiner, Genevieve Neal-Perry, Luhong Wang, Suzanne M Moenter, Aleisha M Moore, Robert L Goodman, Shel Hwa-Yeo, Stephanie L Padilla, Alexander S Kauffman, James Garcia, Martin J Kelly, Jenny Clarkson, Sally Radovick, Andy V Babwah, Silvia Leon, Manuel Tena-Sempere, Alex Comninos, Stephanie Seminara, Waljit S Dhillo, Jon Levine, Ei Terasawa, Ariel Negron, Allan E Herbison
The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond" was held March 30-31 at the Rosen Centre Hotel in Orlando, Florida, providing an international forum for multidisciplinary scientists to meet and share cutting-edge research on kisspeptin biology and its relevance to human health and disease. The meeting built upon previous world conferences focused on the role of kisspeptin and associated peptides in the control of gonadotropin-releasing hormone (GnRH) secretion and reproduction...
April 14, 2018: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29653316/clinical-variability-and-onset-age-modifiers-in-an-extended-belgian-grn-founder-family
#16
Eline Wauters, Sara Van Mossevelde, Kristel Sleegers, Julie van der Zee, Sebastiaan Engelborghs, Anne Sieben, Rik Vandenberghe, Stéphanie Philtjens, Marleen Van den Broeck, Karin Peeters, Ivy Cuijt, Wouter De Coster, Tim Van Langenhove, Patrick Santens, Adrian Ivanoiu, Patrick Cras, Jan L De Bleecker, Jan Versijpt, Roeland Crols, Nina De Klippel, Jean-Jacques Martin, Peter P De Deyn, Marc Cruts, Christine Van Broeckhoven
We previously reported a granulin (GRN) null mutation, originating from a common founder, in multiple Belgian families with frontotemporal dementia. Here, we used data of a 10-year follow-up study to describe in detail the clinical heterogeneity observed in this extended founder pedigree. We identified 85 patients and 40 unaffected mutation carriers, belonging to 29 branches of the founder pedigree. Most patients (74.4%) were diagnosed with frontotemporal dementia, while others had a clinical diagnosis of unspecified dementia, Alzheimer's dementia or Parkinson's disease...
March 10, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29642769/themes-of-healing-and-posttraumatic-growth-in-women-survivors-narratives-of-intimate-partner-violence
#17
Cassandra D'Amore, Stephanie L Martin, Karen Wood, Carolyn Brooks
Research on the effects of intimate partner violence (IPV) on women demonstrates the significant physical, emotional, psychological, and spiritual consequences of this form of interpersonal trauma. It is well documented that experiencing IPV can have devastating consequences to women's physical and mental health, overall well-being, and quality of life, as well as that of their children's. However, a small, predominantly qualitative body of research exists on women's experience of and capacity for healing from the effects of IPV, but more research is needed to advance theory and practice in this important area...
April 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29617911/ontrack-development-and-feasibility-of-a-smartphone-app-designed-to-predict-and-prevent-dietary-lapses
#18
Evan M Forman, Stephanie P Goldstein, Fenqing Zhang, Brittney C Evans, Stephanie M Manasse, Meghan L Butryn, Adrienne S Juarascio, Pramod Abichandani, Gerald J Martin, Gary D Foster
Given that the overarching goal of weight loss programs is to remain adherent to a dietary prescription, specific moments of nonadherence known as "dietary lapses" can threaten weight control via the excess energy intake they represent and by provoking future lapses. Just-in-time adaptive interventions could be particularly useful in preventing dietary lapses because they use real-time data to generate interventions that are tailored and delivered at a moment computed to be of high risk for a lapse...
March 29, 2018: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/29602821/a-prospective-comparison-of-18-f-sodium-fluoride-pet-ct-and-psma-targeted-18-f-dcfbc-pet-ct-in-metastatic-prostate-cancer
#19
Stephanie A Harmon, Ethan Bergvall, Esther Mena, Joanna H Shih, Stephen Adler, Yolanda McKinney, Sherif Mehralivand, Deborah E Citrin, Anna Couvillon, Ravi Madan, James Gulley, Ronnie C Mease, Paula M Jacobs, Martin G Pomper, Baris Turkbey, Peter L Choyke, M Liza Lindenberg
Purpose: The purpose of this study was to compare the diagnostic performance of 18 F-DCFBC positron emission tomography/computed tomography (PET/CT), a first generation 18 F-labelled prostate-specific membrane antigen (PSMA)-targeted agent, and 18 F-NaF PET/CT, a sensitive marker of osteoblastic activity, in a prospective cohort of patients with metastatic prostate cancer. Methods: Twenty-eight prostate cancer patients with metastatic disease on conventional imaging prospectively received up to four PET/CT scans...
March 30, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29580662/duration-of-living-kidney-transplant-donor-evaluations-findings-from-2-multicenter-cohort-studies
#20
Steven Habbous, Jennifer Arnold, Mehmet A Begen, Neil Boudville, Matthew Cooper, Christine Dipchand, Stephanie N Dixon, Liane S Feldman, Dariusz Goździk, Martin Karpinski, Scott Klarenbach, Greg A Knoll, Ngan N Lam, Krista L Lentine, Charmaine Lok, Eric McArthur, Susan McKenzie, Matthew Miller, Mauricio Monroy-Cuadros, Chris Nguan, G V Ramesh Prasad, Sebastian Przech, Sisira Sarma, Dorry L Segev, Leroy Storsley, Amit X Garg
BACKGROUND: A prolonged living kidney donor evaluation may result in worse outcomes for transplant recipients. Better knowledge of the duration of this process may help inform future donors and identify opportunities for improvement. STUDY DESIGN: 1 prospective and 1 retrospective cohort study. SETTING & PARTICIPANTS: At 16 Canadian and Australian transplantation centers (prospective cohort) and 5 Ontario transplantation centers (retrospective cohort), we assessed the duration of living kidney donor evaluation and explored donor, recipient, and transplantation factors associated with longer evaluation times...
March 24, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
keyword
keyword
75863
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"