Ruosu Pan, Chen Ye, Zhimeng Zhang, William Robert Kwapong, Ruilin Wang, Kun Lu, Lanhua Liao, Yuying Yan, Tang Yang, Le Cao, Shuai Jiang, Xuening Zhang, Junfeng Liu, Wendan Tao, Bo Wu
AIMS: Cerebrovascular lesions in the primary visual cortex, the lateral geniculate nucleus, and the optic tract have been associated with retinal neurodegeneration via the retrograde degeneration (RD) mechanism. We aimed to use optical coherence tomography (OCT) to assess the effects of the strategic single subcortical infarction (SSI) location on retinal neurodegeneration and its longitudinal impacts. METHODS: Patients with SSI were enrolled and stratified by lesion location on cerebral MRI into the thalamic infarction group and extra-thalamic infarction group...
November 29, 2023: CNS Neuroscience & Therapeutics