Athina Papadopoulou, Armanda Pfister, Charidimos Tsagkas, Laura Gaetano, Shaumiya Sellathurai, Marcus D'Souza, Nuria Cerdá-Fuertes, Konstantin Gugleta, Maxime Descoteaux, Mallar M Chakravarty, Peter Fuhr, Ludwig Kappos, Cristina Granziera, Stefano Magon, Till Sprenger, Martin Hardmeier
OBJECTIVE: To explore associations of the main component (P100) of visual evoked potentials (VEP) to pre- and postchiasmatic damage in multiple sclerosis (MS). METHODS: 31 patients (median EDSS: 2.5), 13 with previous optic neuritis (ON), and 31 healthy controls had VEP, optical coherence tomography and magnetic resonance imaging. We tested associations of P100-latency to the peripapillary retinal nerve fiber layer (pRNFL), ganglion cell/inner plexiform layers (GCIPL), lateral geniculate nucleus volume (LGN), white matter lesions of the optic radiations (OR-WML), fractional anisotropy of non-lesional optic radiations (NAOR-FA), and to the mean thickness of primary visual cortex (V1)...
February 20, 2024: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology