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https://www.readbyqxmd.com/read/25603124/autonomic-predominant-multiple-system-atrophy-in-the-context-of-parkinsonian-and-cerebellar-variants
#1
Ruchika Tandon, Sunil Pradhan
OBJECTIVES: Autonomic dysfunction is often a late feature of multiple system atrophy (MSA). Based on early features, MSAp (Parkinsonian) and MSAc (cerebellar) variants are known. We studied the severity of autonomic dysfunction at first examination in MSA patient that may have relevance in its early diagnosis. METHODS: Clinical (including autonomic), radiological and lab features of 53 MSA patients were analyzed in the context of MSAp (16 patients) and MSAc (37 patients)...
March 2015: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/25546249/exploring-diversity-in-socioeconomic-inequalities-in-health-among-rural-dwelling-canadians
#2
Bonnie Janzen, Chandima Karunanayake, Punam Pahwa, Roland Dyck, Donna Rennie, Josh Lawson, William Pickett, Rhonda Bryce, Louise Hagel, Guangming Zhao, James Dosman
PURPOSE: To describe the patterning of socioeconomic inequalities in health among rural dwelling women and men in a Canadian province, exploring diversity in associations by measure of socioeconomic position, health outcome, and demographic characteristics. METHODS: Baseline data from the Saskatchewan Rural Health Study was used, an ongoing prospective cohort study examining the health of rural people in Saskatchewan, Canada. Of the 11,004 eligible addresses, responses to mailed questionnaires were obtained from 4,624 (42%) households, representing 8,261 women and men...
2015: Journal of Rural Health
https://www.readbyqxmd.com/read/25380624/effect-of-negative-emotions-evoked-by-light-noise-and-taste-on-trigeminal-thermal-sensitivity
#3
Guangju Yang, Lene Baad-Hansen, Kelun Wang, Qiu-Fei Xie, Peter Svensson
BACKGROUND: Patients with migraine often have impaired somatosensory function and experience headache attacks triggered by exogenous stimulus, such as light, sound or taste. This study aimed to assess the influence of three controlled conditioning stimuli (visual, auditory and gustatory stimuli and combined stimuli) on affective state and thermal sensitivity in healthy human participants. METHODS: All participants attended four experimental sessions with visual, auditory and gustatory conditioning stimuli and combination of all stimuli, in a randomized sequence...
2014: Journal of Headache and Pain
https://www.readbyqxmd.com/read/24643467/interaction-between-selenium-and-mercury-in-biological-samples-of-pakistani-myocardial-infarction-patients-at-different-stages-as-related-to-controls
#4
Hassan Imran Afridi, Tasneem Gul Kazi, Farah Naz Talpur, Atif Kazi, Sadaf Sadia Arain, Salma Aslam Arain, Kapil Dev Brahman, Abdul Haleem Panhwar, Naeemullah
It has been speculated that trace elements may a play role in the pathogenesis of heart diseases. In the present study, we aimed to assess the levels of selenium (Se) and mercury (Hg) in biological samples (whole blood, urine, and scalp hair) of myocardial infarction (MI) patients of both genders (age range 45-60 years) at the first, second, and third heart attack (n = 130), hospitalized in a cardiac ward of a civil hospital of Hyderabad City (Pakistan). For comparison, healthy age-matched referent subjects (n = 61) of both genders were also selected...
May 2014: Biological Trace Element Research
https://www.readbyqxmd.com/read/24466684/-kidney-transplants-from-donors-burdened-metabolic-acidosis-in-the-course-of-poisoning-with-methanol-and-carbon-monoxide
#5
Zbigniew Kołaciński, Agnieszka Skrzypek-Mikulska, Ewelina Pitrus, Józef Matych, Renata Winnicka, Sylwia Czyzewska, Anna Krakowiak
The question of obtaining organs from donors who died of methanol poisoning has been discussed in the medical literature for many years. The results of such transplants published so far are very optimistic. However, the possibility of permanent and significant injury to transplanted organs caused by poisons or its metabolites raises serious concerns regarding the procedure. The long-term effects of intensive treatment of poisoning need to be considered as well. Metabolic acidosis and high blood osmolality are agents with recognized damaging potential impairing organ function at cellular level...
2013: Przegla̧d Lekarski
https://www.readbyqxmd.com/read/23740196/predictors-of-1-year-mortality-in-patients-with-contemporary-guideline-adherent-therapy-after-acute-myocardial-infarction-results-from-the-omega-study
#6
Spyridon Liosis, Timm Bauer, Rudolf Schiele, Helmut Gohlke, Martin Gottwik, Hugo Katus, Georg Sabin, Ralf Zahn, Steffen Schneider, Bernhard Rauch, Jochen Senges, Uwe Zeymer
BACKGROUND: Predictors of long-term mortality after discharge after acute myocardial infarction (AMI) are well characterized. However, these established risk factors are based on data almost exclusively derived from older studies without consistent use of revascularization therapy and adjunctive therapy with statins, platelet inhibitors, beta-blockers and ACE inhibitors/ARBs. We therefore sought to investigate predictors of 1-year mortality in survivors of AMI treated with contemporary guideline-adherent therapy...
September 2013: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/23462524/temperature-myocardial-infarction-and-mortality-effect-modification-by-individual-and-area-level-characteristics
#7
Jaime Madrigano, Murray A Mittleman, Andrea Baccarelli, Robert Goldberg, Steven Melly, Stephanie von Klot, Joel Schwartz
BACKGROUND: Although several studies have examined associations between temperature and cardiovascular-disease-related mortality, fewer have investigated the association between temperature and the development of acute myocardial infarction (MI). Moreover, little is known about who is most susceptible to the effects of temperature. METHODS: We analyzed data from the Worcester Heart Attack Study, a community-wide investigation of acute MI in residents of the Worcester (MA) metropolitan area...
May 2013: Epidemiology
https://www.readbyqxmd.com/read/23270259/-a-case-of-postural-orthostatic-tachycardia-syndrome-pots-with-difficulties-in-differentiation-from-hypoglycemic-attack
#8
Akira Kurozumi, Yosuke Okada, Keiko Nishida, Sunao Yamamoto, Hiroko Mori, Tadashi Arao, Yoshiya Tanaka
A 49-year-old man was referred to our clinic for suspected hypoglycemic symptoms of palpitation, cold sweat, faintness and sinking feeling at movement since 43 years old. The 75 g oral glucose tolerance test showed a decrease in plasma glucose to 56 mg/dl at five hours, but this was not associated with clear hypoglycemic symptoms, and normal plasma glucose level recovered naturally after the test. At 48-hour fasting test, plasma glucose dropped to under 50 mg/dl, but the patient didn't feel hypoglycemia symptom and plasma glucose recovered naturally, but the patient developed cold sweat and hyperventilation after returning to his own room after the test...
December 1, 2012: Journal of UOEH
https://www.readbyqxmd.com/read/23025034/i-am-a-heart-attack-survivor-who-takes-medication-for-hypertension-and-high-cholesterol-both-of-which-seem-to-be-managed-well-i-often-hear-about-the-dangers-of-overdoing-it-in-cold-weather-such-as-too-much-snow-shoveling-but-i-wonder-about-what-precautions
#9
https://www.readbyqxmd.com/read/22899531/protective-effect-of-hypothermia-on-brain-potassium-homeostasis-during-repetitive-anoxia-in-drosophila-melanogaster
#10
Esteban C Rodríguez, R Meldrum Robertson
Oxygen deprivation in nervous tissue depolarizes cell membranes, increasing extracellular potassium concentration ([K(+)](o)). Thus, [K(+)](o) can be used to assess neural failure. The effect of temperature (17, 23 or 29°C) on the maintenance of brain [K(+)](o) homeostasis in male Drosophila melanogaster (w1118) individuals was assessed during repeated anoxic comas induced by N(2) gas. Brain [K(+)](o) was continuously monitored using K(+)-sensitive microelectrodes while body temperature was changed using a thermoelectric cooler (TEC)...
December 1, 2012: Journal of Experimental Biology
https://www.readbyqxmd.com/read/22791002/aortic-valve-replacement-to-a-patient-with-high-titer-of-cold-agglutinin
#11
Rei Kansaku, Kenji Kuwaki, Atsushi Amano, Hirotaka Inaba, Keiichi Tambara, Taira Yamamoto, Naoki Sakakibara
A 60-year-old man was admitted to our hospital because of aortic stenosis with a peak pressure gradient of 61 mmHg, moderate aortic regurgitation, and a dilatation of the ascending aorta of 50 mm in diameter, which had grown 5 mm in 2 years. Because of severe aortic stenosis with a bicuspid valve and fast progression of the ascending aorta in size, replacements of both the aortic valve and the ascending aorta were planned.He had experienced severe acute renal failure with hemolysis because of cold agglutinin one year before the operation...
2012: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/22480655/-mild-stress-as-a-means-to-modulate-aging-from-fly-to-human
#12
REVIEW
Éric Le Bourg
Hormesis is the phenomenon by which adaptive responses to low doses of otherwise harmful conditions improve the functional ability of organisms. Some mild stresses have beneficial effects on longevity, aging and resistance to strong stresses (heat or cold shocks, infection) in Drosophila flies. Studies on rodents are indeed scarce but mild stress seems to be effective in humans because, for instance, patients suffering from angina have a higher survival when confronted with a heart attack. A few studies, in less tragic situations however, suggest that mild stress could have positive effects in elderly people...
March 2012: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/21267037/cardiovascular-effects-of-spinal-cord-stimulation-in-hypertensive-patients
#13
David M Schultz, Xiaohong Zhou, Ashish Singal, Shailesh Musley
BACKGROUND: Several animal and clinical studies have shown that thoracic spinal cord stimulation (SCS) may decrease mean arterial pressure (MAP). A previous study in normotensive participants demonstrated a small reduction in MAP during SCS at the T5-T6 spinal level. It has also been demonstrated that chronic SCS at the subthreshold stimulation level significantly improved angina attacks and 6-minute hall walk distance in drug refractory angina patients. OBJECTIVES: To determine if thoracic SCS at 2 different stimulation strengths would decrease blood pressure (BP) and heart rate (HR) during baseline conditions and during activation of the sympathetic system by the cold pressor test (CPT)...
January 2011: Pain Physician
https://www.readbyqxmd.com/read/21062469/perceptions-of-personal-health-risks-by-medical-and-non-medical-workers-in-a-university-medical-center-a-survey-study
#14
Tita Alissa Listyowardojo, Raoul E Nap, Addie Johnson
BACKGROUND: Health care workers (HCWs) are faced with many work-related choices which may depend on how they perceive risk, such as whether or not to comply with safety regulations. Little research has investigated risk perception in medical workers in comparison with non-medical workers and the extent to which risk perception differs in these groups. The current study thus investigates risk perception of medical and non-medical workers to inform and complement future research on safety compliance...
2010: BMC Public Health
https://www.readbyqxmd.com/read/20589961/by-the-way-doctor-when-i-attempt-to-go-into-the-outdoor-pool-at-my-beach-club-i-gasp-for-breath-get-dizzy-and-light-headed-and-have-to-get-out-several-years-ago-i-read-an-article-that-some-people-who-are-very-sensitive-to-cold-water-may-sustain-a-heart-attack
#15
https://www.readbyqxmd.com/read/20572404/combined-spinal-general-anesthesia-with-postoperative-femoral-nerve-block-for-total-knee-replacement-in-a-patient-with-familial-hyperkalemic-periodic-paralysis-a-case-report
#16
Maria C Barker
Familial hyperkalemic periodic paralysis (HYPP) is a rare genetic disorder in which the sodium channels in skeletal muscle cells have altered structure and function. Small elevations in serum potassium lead to inactivation of sodium channels, causing episodic weakness or paralysis. Exposure to cold, anesthesia, fasting, emotional stress, potassium ingestion, and rest after exercise can stimulate an attack. This case report describes a 65-year-old man with HYPP who was admitted for a right total knee arthroplasty...
June 2010: AANA Journal
https://www.readbyqxmd.com/read/20442827/occupational-lifestyle-diseases-an-emerging-issue
#17
Mukesh Sharma, P K Majumdar
Lifestyle diseases characterize those diseases whose occurrence is primarily based on the daily habits of people and are a result of an inappropriate relationship of people with their environment. The main factors contributing to lifestyle diseases include bad food habits, physical inactivity, wrong body posture, and disturbed biological clock. A report, jointly prepared by the World Health Organization (WHO) and the World Economic Forum, says India will incur an accumulated loss of $236.6 billion by 2015 on account of unhealthy lifestyles and faulty diet...
December 2009: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/20186674/functional-vascular-diseases-raynaud-s-syndrome-acrocyanosis-and-erythromelalgia
#18
REVIEW
H Heidrich
Raynauds syndrome, acrocyanosis and erythromelalgia are functional vascular diseases that differ with respect to prevalence, clinical picture, therapy, prognosis, and impairment of quality of life. Raynauds syndrome occurs in 5 to 20 % of the population in Europe, is observed four times more often in women than in men and appears first at the age of 40 (3 to 80), on the average. Raynauds attacks are characterized by a paroxysmal white-blue-red or just white and blue discoloration of the fingers and toes; the attacks are induced by cold or stress, usually, cease after no more than some minutes (average 23 min...
February 2010: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/20143684/-sole-guardian-s-death-as-a-cause-of-his-handicapped-mother-s-death-a-case-report
#19
Anna Niemcunowicz-Janica, Iwona Ptaszyńska-Sarosiek, Jerzy Janica, Zofia Wardaszka, Magdalena Okłota, Witold Pepiński
Finding more than one body in the place of residence brings suspicion of poisoning or action of a third party. The authors present a case of two bodies--a handicapped mother and her son--found in their own house. The son was last seen by their neighbours three days before the bodies were revealed. There was a stove in the house which was cold with no signs of penetration. No indication of a third party action was found on the corpses. The autopsy on the son revealed a heart attack with subsequent rupture and tamponade which resulted in death...
2007: Annales Academiae Medicae Stetinensis
https://www.readbyqxmd.com/read/19822448/severe-respiratory-phenotype-caused-by-a-de-novo-arg528gly-mutation-in-the-cacna1s-gene-in-a-patient-with-hypokalemic-periodic-paralysis
#20
Tae-Hwan Kil, June-Bum Kim
Hypokalemic periodic paralysis (HOKPP) is a rare disorder characterized by episodic muscle weakness with hypokalemia. Mutations in the CACNA1S gene, which encodes the alpha 1-subunit of the skeletal muscle L-type voltage-dependent calcium channel, have been reported to be mainly responsible for HOKPP. The paralytic attacks generally spare the respiratory muscles and the heart. Here, we report the case of a 16-year-old boy who presented with frequent respiratory insufficiency during the severe attacks. Mutational analysis revealed a heterozygous c...
May 2010: European Journal of Paediatric Neurology: EJPN
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