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Oct coregistration

Mieke T J Bus, Paul Cernohorsky, Daniel M de Bruin, Sybren L Meijer, Geert J Streekstra, Dirk J Faber, Guido M Kamphuis, Patricia J Zondervan, Marcel van Herk, Maria P Laguna Pes, Maik J Grundeken, Martin J Brandt, Theo M de Reijke, Jean J M C H de la Rosette, Ton G van Leeuwen
Minimal invasive endoscopic treatment for upper urinary tract urothelial carcinoma (UUT-UC) is advocated in patients with low-risk disease and limited tumor volume. Diagnostic ureterorenoscopy combined with biopsy is the diagnostic standard. This study aims to evaluate two alternative diagnostic techniques for UUT-UC: optical coherence tomography (OCT) and endoluminal ultrasound (ELUS). Following nephroureterectomy, OCT, ELUS, and computed tomography (CT) were performed of the complete nephroureterectomy specimen...
January 2018: Journal of Medical Imaging
Ang Li, Jiang You, Congwu Du, Yingtian Pan
Angiogenesis is recognized as a crucial component of many neurovascular diseases such as stroke, carcinogenesis, and neurotoxicity of abused drug. The ability to track angiogenesis will facilitate a better understanding of disease progression and assessment of therapeutical effects. Optical coherence angiography (OCTA) is a promising tool to assess 3D microvascular networks due to its micron-level resolution, high sensitivity, and relatively large field of view. However, quantitative OCTA image analysis for characterization of microvascular network changes, including accurately tracking the progression of angiogenesis, remains a challenge...
December 1, 2017: Biomedical Optics Express
David M Leistner, Matthias Riedel, Lisa Steinbeck, Barbara E Stähli, Georg M Fröhlich, Alexander Lauten, Carsten Skurk, Hans-Christian Mochmann, Laura Lübking, Ursula Rauch-Kröhnert, Renate B Schnabel, Dirk Westermann, Stefan Blankenberg, Ulf Landmesser
AIMS: Intracoronary optical coherence tomography (OCT) imaging allows for high-resolution characterization of coronary lesions. Difficulties in matching cross-sectional OCT-images with angiographic lesion localization may limit optimal clinical utilization. We sought to prospectively assess the impact of a novel system of real-time OCT coregistration with angiography (ACR) on physician decision-making during percutaneous coronary interventions (PCI). METHODS AND RESULTS: Strategy for PCI (stent - length, - diameter, - strategy, landing zone) and PCI-optimization (stent-malappostion, -underexpansion, edge-dissections, geographical mismatch) was prospectively assessed in 50 patients with 58 coronary lesions after (I) angiography, (II) OCT imaging, and (III) ACR...
September 20, 2017: Catheterization and Cardiovascular Interventions
Joël Lefebvre, Alexandre Castonguay, Philippe Pouliot, Maxime Descoteaux, Frédéric Lesage
An automated massive histology setup combined with an optical coherence tomography (OCT) microscope was used to image a total of [Formula: see text] whole mouse brains. Each acquisition generated a dataset of thousands of OCT volumetric tiles at a sampling resolution of [Formula: see text]. This paper describes techniques for reconstruction and segmentation of the sliced brains. In addition to the measured OCT optical reflectivity, a single scattering photon model was used to compute the attenuation coefficients within each tissue slice...
October 2017: Neurophotonics
Ryan N Vogel, Christopher S Langlo, Drew Scoles, Joseph Carroll, David V Weinberg, Judy E Kim
Purpose: We improved our understanding of central serous chorioretinopathy (CSC), we performed an analysis of noninvasive, high-resolution retinal imaging in patients with active and resolved CSC. Methods: Adaptive optics scanning light ophthalmoscopy (AOSLO) and spectral-domain optical coherence tomography (SD-OCT) were performed on five subjects with CSC. A custom AOSLO system was used to simultaneously collect confocal and split-detector images. Spectral domain-OCT volume scans were used to create en face views of various retinal layers, which then were compared to montaged AOSLO images after coregistration...
January 1, 2017: Investigative Ophthalmology & Visual Science
Christoph Lutter, Hiroyoshi Mori, Kazuyuki Yahagi, Elena Ladich, Michael Joner, Robert Kutys, David Fowler, Maria Romero, Jagat Narula, Renu Virmani, Aloke V Finn
OBJECTIVES: The aim of this study was to identify histological features that correlate with terms commonly used to describe optical coherence tomographic (OCT) and optical frequency-domain imaging (OFDI) images of stented vessels, by means of a histopathological validation study using stented human coronary arteries. BACKGROUND: OCT imaging and OFDI are used to evaluate vascular responses to stent implantation. Descriptive terms such as "peristrut low attenuation" and "heterogeneous" have been used to describe neointimal characteristics that may have clinical relevance...
December 26, 2016: JACC. Cardiovascular Interventions
Nariaki Yoshimine, Yasushi Shimada, Junji Tagami, Alireza Sadr
PURPOSE: To investigate the effects of placement technique and adhesive material on adaptation of composites before and after light curing. MATERIALS AND METHODS: Cylindrical cavities (3 mm diameter, 1.7 mm depth) in extracted human molars were restored in 6 groups (n=5) using 2 adhesives--two-step self-etching Clearfil SE Bond 2 (SE2) and all-in-one Clearfil Tri-S Bond Plus (TSP) (Kuraray Noritake Dental)--and 2 composites--Estelite Sigma Quick (ESQ) and Estelite Flow Quick (FLQ) (Tokuyama Dental)--placed with three different techniques: ESQ bulk placed, FLQ lining followed by ESQ and FLQ bulk placed...
August 2015: Journal of Adhesive Dentistry
Berrend G Muller, Daniel M de Bruin, Willemien van den Bos, Martin J Brandt, Juliette F Velu, Mieke T J Bus, Dirk J Faber, Dilara Savci, Patricia J Zondervan, Theo M de Reijke, Pilar Laguna Pes, Jean de la Rosette, Ton G van Leeuwen
The objective of this study is to demonstrate the feasibility of needle-based optical coherence tomography (OCT) and functional analysis of OCT data along the full pullback trajectory of the OCT measurement in the prostate, correlated with pathology. OCT images were recorded using a commercially available C7-XR™ OCT Intravascular Imaging System interfaced to a C7 Dragonfly™ intravascular 0.9-mm-diameter imaging probe. A computer program was constructed for automated image attenuation analysis. First, calibration of the OCT system for both the point spread function and the system roll-off was achieved by measurement of the OCT signal attenuation from an extremely weakly scattering medium (Intralipid® 0...
July 2015: Journal of Medical Imaging
Stylianos A Pyxaras, Shengxian Tu, Emanuele Barbato, Johan H C Reiber, William Wijns
No abstract text is available yet for this article.
July 2013: JACC. Cardiovascular Interventions
Caroline Malle, Tomohisa Tada, Kristin Steigerwald, Giovanni J Ughi, Tibor Schuster, Masataka Nakano, Steffen Massberg, Johannes Jehle, Giulio Guagliumi, Adnan Kastrati, Renu Virmani, Robert A Byrne, Michael Joner
OBJECTIVE: To validate optical coherence tomography (OCT) imaging for assessment of vascular healing in a preclinical animal model and human autopsy cases and to translate the findings to the assessment of vascular healing after drug-eluting stent implantation in clinical practice. APPROACH AND RESULTS: Drug-eluting and bare metal stents were imaged 28 and 42 days after implantation in atherosclerotic rabbits using OCT and simultaneously evaluated by histology. After coregistration with histology, gray-scale signal intensity (GSI) was measured for identified mature or immature neointimal tissue...
June 2013: Arteriosclerosis, Thrombosis, and Vascular Biology
Eva Lenassi, Eric Troeger, Robert Wilke, Adnan Tufail, Marko Hawlina, Glen Jeffery, Andrew R Webster
PURPOSE: To assess whether laser treatment to the retinal pigment epithelium anterior to drusen in eyes of patients with EFEMP1-related maculopathy affects visual acuity, deposit volume, and retinal sensitivity. DESIGN: Prospective, interventional case series. METHODS: In 11 patients with autosomal dominant drusen and confirmed disease-causing EFEMP1 mutation, the worse-seeing eye was treated with Argon green laser (10 to 15 laser spots; 200-μm spot size, 0...
January 2013: American Journal of Ophthalmology
Francisco A Folgar, Jessica H Chow, Sina Farsiu, Wai T Wong, Stefanie G Schuman, Rachelle V O'Connell, Katrina P Winter, Emily Y Chew, Thomas S Hwang, Sunil K Srivastava, Molly W Harrington, Traci E Clemons, Cynthia A Toth
PURPOSE: Macular hyperpigmentation is associated with progression from intermediate to advanced age-related macular degeneration (AMD). The purpose of this study was to accurately correlate hyperpigmentary changes with spectral domain optical coherence tomography (SDOCT) hyperreflective foci in eyes with non-advanced AMD. METHODS: A prospective cross-sectional analysis of 314 eyes (314 subjects) with intermediate AMD was performed in the multicenter Age-Related Eye Disease Study 2 (AREDS2) Ancillary SDOCT Study to correlate hyperpigmentary changes on color fundus photographs (CFP) with abnormal morphology on SDOCT...
2012: Investigative Ophthalmology & Visual Science
Eva Lenassi, Eric Troeger, Robert Wilke, Marko Hawlina
PURPOSE: To assess the correlation between retinal morphology and function in patients with retinitis pigmentosa (RP) using spectral domain optical coherence tomography (SD-OCT), fundus autofluorescence imaging (FAF), and fundus-related perimetry and to use coregistration of data sets to achieve high-resolution structure-function correlation of human macula. METHODS: Twelve patients with RP and hyperautofluorescent parafoveal ring in FAF imaging were tested. Ophthalmological examination, static and kinetic fundus-related perimetry, and SD-OCT were performed...
January 2012: Investigative Ophthalmology & Visual Science
Fabian Kiessling, Daniel Razansky, Frauke Alves
PURPOSE: This article reviews and discusses different options for visualizing the microarchitecture of vessels ex vivo and in vivo with respect to reliability, practicability and availability. RESULTS AND DISCUSSION: The investigation of angiogenesis by standard histological methods, like microvessel density counts, is limited since the three-dimensional (3-D) architecture and the functionality of vessels cannot be considered properly. Coregistration of immunostained images of vessels may be performed but is time consuming and often not sufficiently accurate...
August 2010: European Journal of Nuclear Medicine and Molecular Imaging
Hamid R Djalilian, James Ridgway, Majestic Tam, Ali Sepehr, Zhongping Chen, Brian J F Wong
OBJECTIVE: Optical coherence tomography (OCT) is a diagnostic imaging modality that combines low coherence light with interferometry to produce high-resolution cross-sectional images of living tissues. Using this technology, we have imaged in vivo the human tympanic membrane (TM) in the office clinic setting and characterized TM microstructure in normal and pathologic conditions. STUDY DESIGN: Prospective clinical trial. MATERIALS AND METHODS: The normal and diseased TMs in 10 adult subjects were examined...
December 2008: Otology & Neurotology
S H Dresel, M P Kung, X F Huang, K Plössl, C Hou, S K Meegalla, G Patselas, M Mu, J R Saffer, H F Kung
UNLABELLED: The central nervous system dopamine transporters (DATs) and dopamine D2/D3 receptors are implicated in a variety of neurological disorders. Both sites are also targets for drug treatment. With the successful development of [99mTc]TRODAT-1, single-isotope imaging studies using this ligand for DAT imaging can be complemented by additional use of 123I-labeled D2/D3 receptor ligand co-injected to assess both pre- and postsynaptic sites of the dopaminergic system simultaneously...
April 1999: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
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