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https://www.readbyqxmd.com/read/28710409/machine-learning-algorithms-for-risk-prediction-of-severe-hand-foot-mouth-disease-in-children
#1
Bin Zhang, Xiang Wan, Fu-Sheng Ouyang, Yu-Hao Dong, De-Hui Luo, Jing Liu, Long Liang, Wen-Bo Chen, Xiao-Ning Luo, Xiao-Kai Mo, Lu Zhang, Wen-Hui Huang, Shu-Fang Pei, Bao-Liang Guo, Chang-Hong Liang, Zhou-Yang Lian, Shui-Xing Zhang
The identification of indicators for severe HFMD is critical for early prevention and control of the disease. With this goal in mind, 185 severe and 345 mild HFMD cases were assessed. Patient demographics, clinical features, MRI findings, and laboratory test results were collected. Gradient boosting tree (GBT) was then used to determine the relative importance (RI) and interaction effects of the variables. Results indicated that elevated white blood cell (WBC) count > 15 × 10(9)/L (RI: 4(9).47, p < 0...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28705216/surgical-management-of-hawkins-type-iii-talar-neck-fracture-through-the-approach-of-medial-malleolar-osteotomy-and-mini-plate-for-fixation
#2
Hui Liu, Zhida Chen, Wenrong Zeng, Yuanfei Xiong, Yongzhi Lin, Huacheng Zhong, Jin Wu
BACKGROUND: Fractures of the talar neck are relatively uncommon yet current interventions suffer from a high incidence of complications and poor functional outcomes. In the present study, we report a surgical treatment of Hawkins type III talar neck fracture through the approach of medial malleolar osteotomy and mini-plate for fixation and discuss the therapeutic effects after long-term follow-up. METHODS: From January 2010 to January 2015, 21 patients with 22 fractures were treated using this approach within days of sustaining the injury...
July 14, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28704615/case-study-solitary-benign-schwannoma-of-the-foot-presenting-clinically-as-a-ganglion-cyst
#3
Peter Ly
An unusual case of solitary benign schwannoma of the foot is presented. Clinical exam, MRI, and intra operative findings all confirm suspicion of a ganglion cyst. After attempt aspiration failed to produce any aspirate, excisional biopsy was performed. Pathology report confirms schwannoma with H&E stain, and subsequently reaffirmed with positive S-100 protein stain. Even though schwannoma of the foot had been reported in literature, this was an unusual case as the lesion was presented as a superficial, ganglion cyst like lesion on the bottom of the foot...
July 13, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28700527/magnetic-resonance-imaging-in-psoriatic-arthritis-a-descriptive-study-of-indications-features-and-effect-on-treatment-change
#4
Hernán Maldonado-Ficco, Barry J Sheane, Arane Thavaneswaran, Vinod Chandran, Dafna D Gladman
OBJECTIVE: The aims of this study were to describe the indications for, and features of, axial/peripheral joint magnetic resonance imaging (MRI) in psoriatic arthritis (PsA) and to examine the influence of MRI findings on clinical practice. METHODS: All axial and peripheral (hand and/or foot) MRI scans on patients attending the Toronto PsA clinic l between 2003 and 2014 were included. Scan details were garnered from the radiologist's official report. A chart review was performed to determine if MRI findings contributed to a change of treatment...
July 11, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28681515/accuracy-of-open-magnetic-resonance-imaging-for-guiding-injection-of-the-equine-deep-digital-flexor-tendon-within-the-hoof
#5
Lauren M Groom, Nathaniel A White, M Norris Adams, Jennifer G Barrett
Lesions of the distal deep digital flexor tendon (DDFT) are frequently diagnosed using MRI in horses with foot pain. Intralesional injection of biologic therapeutics shows promise in tendon healing; however, accurate injection of distal deep digital flexor tendon lesions within the hoof is difficult. The aim of this experimental study was to evaluate accuracy of a technique for injection of the deep digital flexor tendon within the hoof using MRI-guidance, which could be performed in standing patients. We hypothesized that injection of the distal deep digital flexor tendon within the hoof could be accurately guided using open low-field MRI to target either the lateral or medial lobe at a specific location...
July 6, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28680701/finger-and-foot-tapping-as-alternative-outcomes-of-upper-and-lower-extremity-function-in-multiple-sclerosis
#6
Makoto Tanigawa, Jason Stein, John Park, Peter Kosa, Irene Cortese, Bibiana Bielekova
BACKGROUND: While magnetic resonance imaging contrast-enhancing lesions represent an excellent screening tool for disease-modifying treatments in relapsing-remitting multiple sclerosis (RRMS), this biomarker is insensitive for testing therapies against compartmentalized inflammation in progressive multiple sclerosis (MS). Therefore, alternative sensitive outcomes are needed. Using machine learning, clinician-acquired disability scales can be combined with timed measures of neurological functions such as walking speed (e...
January 2017: Multiple Sclerosis Journal—Experimental, Translational and Clinical
https://www.readbyqxmd.com/read/28661227/a-preliminary-study-of-patient-specific-mechanical-properties-of-diabetic-and-healthy-plantar-soft-tissue-from-gated-magnetic-resonance-imaging
#7
Evan D Williams, Michael J Stebbins, Peter R Cavanagh, David R Haynor, Baocheng Chu, Michael J Fassbind, Vara Isvilanonda, William R Ledoux
Foot loading rate, load magnitude, and the presence of diseases such as diabetes can all affect the mechanical properties of the plantar soft tissues of the human foot. The hydraulic plantar soft tissue reducer instrument was designed to gain insight into which variables are the most significant in determining these properties. It was used with gated magnetic resonance imaging to capture three-dimensional images of feet under dynamic loading conditions. Custom electronics controlled by LabVIEW software simultaneously recorded system pressure, which was then translated to applied force values based on calibration curves...
July 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28647522/functional-medium-term-results-after-autologous-matrix-induced-chondrogenesis-for-osteochondral-lesions-of-the-talus-a-5-year-prospective-cohort-study
#8
Oliver Gottschalk, Sebastian Altenberger, Sebastian Baumbach, Stefanie Kriegelstein, Florian Dreyer, Alexander Mehlhorn, Hubert Hörterer, Andreas Töpfer, Anke Röser, Markus Walther
Autologous matrix-induced chondrogenesis (AMIC) has gained popularity in the treatment of osteochondral lesions of the talus. Previous studies have presented promising short-term results for AMIC talar osteochondral lesion repair, a 1-step technique using a collagen type I/III bilayer matrix. The aim of the present study was to investigate the mid-term effects. The 5-year results of a prospective cohort study are presented. All patients underwent an open AMIC procedure for a talar osteochondral lesion. Data analysis included general demographic data, preoperative magnetic resonance imaging findings, intraoperative details, and German version of the Foot Function Index (FFI-D) scores preoperatively and at 1 and 5 years after surgery...
June 21, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28634696/prominent-midfoot-involvement-in-children-with-enthesitis-related-arthritis-category-of-juvenile-idiopathic-arthritis
#9
Sanat Phatak, Namita Mohindra, Abhishek Zanwar, Amita Aggarwal
Foot involvement is common in juvenile idiopathic arthritis (JIA) but is often unrecognized and difficult to treat. This study was done to assess clinical and radiological involvement of the feet and its impact on function in Indian children with enthesitis-related arthritis (ERA). We enrolled consecutive children with ERA with disease duration of less than 5 years. All patients underwent clinical examination of the feet and filled the juvenile arthritis foot index (JAFI) questionnaire. Ultrasound (US) of foot joints and entheses and extremity magnetic resonance imaging (MRI) scan of one foot were done...
June 20, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28633797/sponge-rubber-revealed-two-years-after-penetrating-injury-a%C3%A2-case%C3%A2-report
#10
Sandor Roth, Maja Zaninovic, Aron Roth
The present report illustrates a very rare case report of a foreign body granuloma of the foot associated with a 2-year period of a retained spongeous rubber foreign body after a penetrating injury. Because it appeared almost 2 years after the injury, the history of trauma was minimized, the foreign body had migrated from the plantar to the dorsal side of the foot, and the radiographic appearance resembled a malignant process, it was difficult to rule out the possibility of a malignant tumor. This case shows the weakness of magnetic resonance imaging in detecting spongeous rubber in the body...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28633794/glomus-tumor-in-the-tarsal-tunnel-a-case-report
#11
Azusa Yoneda, Kazuya Sugimoto, Naoki Tsukada, Kensuke Okamura, Shinji Isomoto, Norihiro Samoto, Yasuhito Tanaka
Glomus tumors are painful benign neoplasms. They commonly present in the hand and are mostly solitary lesions. We report a rare case of multiple glomus tumors in the lower leg. Moreover, 1 of the tumors was in the tarsal tunnel. Resection of the tumors resulted in the early diagnosis of glomus tumors and complete symptom relief. Because of its rarity, diagnosing an extradigital glomus tumor is difficult. Recognition of glomus tumors allows for an early diagnosis and resection, and preoperative magnetic resonance imaging helps in the detection of multiple lesions...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28633776/bioabsorbable-calcaneo-stop-implant-for-the-treatment-of-flexible-flatfoot-a-retrospective-cohort-study-at-a-minimum-follow-up-of-4%C3%A2-years
#12
Sandro Giannini, Matteo Cadossi, Antonio Mazzotti, Valentina Persiani, Giuseppe Tedesco, Matteo Romagnoli, Cesare Faldini
Arthroereisis of the subtalar joint is a common surgical technique in Europe for the management of flexible flatfoot in the pediatric population. In most cases, it is performed using a calcaneo-stop metallic screw. Despite the good clinical results, screw removal is always advised after 2 to 3 years. The use of a bioabsorbable screw might overcome the need for a second operation to remove a nonabsorbable device. We report the results of a biodegradable calcaneo-stop screw at a minimum of 4 years of follow-up...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28633773/magnetic-resonance-imaging-and-clinical-outcomes-of-laser-therapy-ultrasound-therapy-and-extracorporeal-shock-wave-therapy-for-treatment-of-plantar-fasciitis-a-randomized-controlled-trial
#13
Aslihan Ulusoy, Lale Cerrahoglu, Sebnem Orguc
We determined and compared the effectiveness of low-level laser therapy (LLLT), therapeutic ultrasound (US) therapy, and extracorporeal shock wave therapy (ESWT) using magnetic resonance imaging (MRI). We performed a randomized, prospective, comparative clinical study. A total of 60 patients with a diagnosis of chronic plantar fasciitis were divided randomly into 3 treatment groups: group 1 underwent 15 sessions of LLLT (8 J/cm(2); 830 nm); group 2 underwent 15 sessions of continuous US (1 mHz; 2 W/cm(2)); and group 3 underwent 3 sessions of ESWT (2000 shocks)...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28631141/cell-labeling-with-magneto-endosymbionts-and-the-dissection-of-the-subcellular-location-fate-and-host-cell-interactions
#14
Kayla R Lee, Abdul Wakeel, Papia Chakraborty, Chandler S Foote, Lauren Kajiura, Joyce C Barrozo, Andrea C Chan, Alexey V Bazarov, Ryan Spitler, Peter M Kutny, Jim M Denegre, Rob A Taft, Joachim Seemann, Bradley W Rice, Christopher H Contag, Brian K Rutt, Caleb B Bell
PURPOSE: The purposes of this study are to characterize magneto-endosymbiont (ME) labeling of mammalian cells and to discern the subcellular fate of these living contrast agents. MEs are novel magnetic resonance imaging (MRI) contrast agents that are being used for cell tracking studies. Understanding the fate of MEs in host cells is valuable for designing in vivo cell tracking experiments. PROCEDURES: The ME's surface epitopes, contrast-producing paramagnetic magnetosomal iron, and genome were studied using immunocytochemistry (ICC), Fe and MRI contrast measurements, and quantitative polymerase chain reaction (qPCR), respectively...
June 19, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28630831/unusual-presentation-of-mycetoma-of-the-foot-a-rare-case-report
#15
Amit Grover, Prashanth Nagaraj, Vinay M Joseph, Daksh Gadi
INTRODUCTION: Mycetoma is a chronic granulomatous infection. It is caused by actinomycetes or fungi. It is common in tropical countries and males. Predisposing conditions include malnutrition, poor hygiene, history of trauma, wounds on barefeet, and systemic infections. Eumycotic mycetoma commonly involves lower extremities whereas actinomycosis affects the cervicofacial, thoracic, and abdominal regions. Mycetoma presents with a chronic indurated ulcerated plague with swelling and yellowish discharge of sulfur granules...
January 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28629975/anatomical-and-functional-properties-of-the-foot-and-leg-representation-in-areas-3b-1-and-2-of-primary-somatosensory-cortex-in-humans-a-7t-fmri-study
#16
Michel Akselrod, Roberto Martuzzi, Andrea Serino, Wietske van der Zwaag, Roger Gassert, Olaf Blanke
Primary somatosensory cortex (S1) processes somatosensory information and is composed of multiple subregions. In particular, tactile information from the skin is encoded in three subregions, namely Brodmann areas (BAs) 3b, 1 and 2, with each area representing a complete map of the contralateral body. Although, much is known about the somatotopic organization of the hand in human S1, less research has been carried out regarding the somatotopic maps of the foot and leg in S1. Moreover, a latero-medial S1 organization along the superior part of the postcentral gyrus has been reported when moving from hip to toes, yet to date there is no study investigating leg/foot maps within the different subregions of S1...
June 16, 2017: NeuroImage
https://www.readbyqxmd.com/read/28616842/characterization-of-magneto-endosymbionts-as-mri-cell-labeling-and-tracking-agents
#17
Kimberly D Brewer, Ryan Spitler, Kayla R Lee, Andrea C Chan, Joyce C Barrozo, Abdul Wakeel, Chandler S Foote, Steven Machtaler, James Rioux, Juergen K Willmann, Papia Chakraborty, Bradley W Rice, Christopher H Contag, Caleb B Bell, Brian K Rutt
PURPOSE: Magneto-endosymbionts (MEs) show promise as living magnetic resonance imaging (MRI) contrast agents for in vivo cell tracking. Here we characterize the biomedical imaging properties of ME contrast agents, in vitro and in vivo. PROCEDURES: By adapting and engineering magnetotactic bacteria to the intracellular niche, we are creating magneto-endosymbionts (MEs) that offer advantages relative to passive iron-based contrast agents (superparamagnetic iron oxides, SPIOs) for cell tracking...
June 14, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28603855/stress-fractures-of-the-calcaneus-diagnosed-by-sonography-report-of-8-cases
#18
Stefano Bianchi, Dien Hung Luong
We present a retrospective review of 8 patients (6 women and 2 men, with an age range of 46-80 years; mean age, 60.2 years) in whom sonography was used to diagnose a calcaneal stress fracture. Sonography was performed because of a clinical suspicion of soft tissue injuries. Two patients were first assessed by standard radiography; for the remaining patients, sonography was the first imaging technique used. Patients were subsequently examined by magnetic resonance imaging, except for 1 patient in whom the diagnosis was made only on a clinical-sonographic correlation...
June 12, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28602429/unusual-presentation-of-foreign-body-granuloma-of-the-foot-after-sharp-injury-mimicking-a-malignant-lesion-a-case-report
#19
Narendran Pushpasekaran, Manoharan Muthulingam, Chandrasekaran Marimuthu, Rajan Babu, Naveen Kumar Rajapalani Kumar
Foot foreign body granulomas can mimic malignancies, especially when the history and unusual location pose a diagnostic dilemma. We report the case of a 33-year-old male with delayed-onset progressive swelling over the foot dorsum after a sharp injury through the plantar aspect of the foot. The unusual presentation and radiolucency warranted further radiologic evaluation, which revealed a benign foot swelling. An excision biopsy and histopathologic examination revealed a rubber body granuloma. No recurrence of the granuloma was noted during the 11-month follow-up period after removal of the offending agent...
June 8, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28600017/comparison-of-prenatal-and-postnatal-management-of-patients-with-myelomeningocele
#20
REVIEW
Sergio Cavalheiro, Marcos Devanir Silva da Costa, Antonio Fernandes Moron, Jeffrey Leonard
Myelomeningocele (MMC) is a costly lifetime disease with many comorbidities, including sensory and motor lower limb disability, bladder/bowel dysfunction, scoliosis, club foot, and hydrocephalus. MMC treatment options have changed over time because routine use of fetal ultrasonography and MRI has provided prenatal diagnosis and the potential for fetal surgery. There is still no consensus on how to treat the MMC diagnoses prenatally, mainly related to the infrastructure required to operate on pregnant patients...
July 2017: Neurosurgery Clinics of North America
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