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https://www.readbyqxmd.com/read/28723993/healthcare-and-development-a-dialog-with-the-thinking-of-celso-furtado
#1
Laís Silveira Costa, Ligia Bahia, Patrícia Seixas da Costa Braga
Understanding that conditions of health are dependent on more general nationwide factors relating to the level of development means admitting that 'sectorization' of health service is something that tends to limit the formation of knowledge. It also points to the importance of investigating the relationship between health and development, including issues about the processes that feed the persistence of the polarization between modernization and exclusion which has been a history of Brazil's contemporary development...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28723992/social-inequalities-in-the-face-of-scientific-and-technological-development-an-antinomy-or-an-historic-problem
#2
Guilherme Costa Delgado
This paper aims to conduct a conceptual analysis of the relationship between scientific and technical progress and social equality, or the reduction of inequalities. We examine this relationship by drawing on three theoretical perspectives: 1) ethical economics, championed by classical economic thinkers and centered on utilitarian self-interest, 2) Mainstream theories of economic development espousing the endogenous link between labor productivity growth and technical progress, 3) the critique of theories of economic development that emerged in the second half of the twentieth century, including Celso Furtado's critique of the theory of underdevelopment, emphasizing the prevalence of egalitarian tendencies, and ecological economics, which suggest alternative paths to those set by "classical" theories of development...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28710436/epithelial-derived-il-33-promotes-intestinal-tumorigenesis-in-apc-min-mice
#3
Zhengxiang He, Lili Chen, Fabricio O Souto, Claudia Canasto-Chibuque, Gerold Bongers, Madhura Deshpande, Noam Harpaz, Huaibin M Ko, Kevin Kelley, Glaucia C Furtado, Sergio A Lira
Increased expression of Interleukin (IL)-33 has been detected in intestinal samples of patients with ulcerative colitis, a condition associated with increased risk for colon cancer, but its role in the development of colorectal cancer has yet to be fully examined. Here, we investigated the role of epithelial expressed IL-33 during development of intestinal tumors. IL-33 expression was detected in epithelial cells in colorectal cancer specimens and in the Apc (Min/+) mice. To better understand the role of epithelial-derived IL-33 in the intestinal tumorigenesis, we generated transgenic mice expressing IL-33 in intestinal epithelial cells (V33 mice)...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28690085/comparison-of-cone-beam-computed-tomography-and-digital-intraoral-radiography-performance-in-the-detection-of-artificially-induced-recurrent-caries-like-lesions
#4
Saulo Leonardo Sousa Melo, Manuella Dias Furtado Belem, Lucia Trazzi Prieto, Cinthia Pereira Machado Tabchoury, Francisco Haiter-Neto
OBJECTIVES: The aim of this study was to compare the performance of cone beam computed tomography (CBCT) and digital radiography in the detection of artificial recurrent caries-like lesions under amalgam and composite fillings. STUDY DESIGN: The study included class II cavities in 30 molars that had been filled with amalgam. Fifteen of those molars had the restoration-enamel interface artificially demineralized. Phantoms were prepared, and CBCT images were acquired with 2 units in 3 voxel sizes (K9000, 0...
May 11, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28684550/frutapin-a-lectin-from-artocarpus-incisa-breadfruit-cloning-expression-and-molecular-insights
#5
Felipe Domingos Sousa, Bruno Bezerra da Silva, Gilvan Pessoa Furtado, Igor de Sa Carneiro, Marina Duarte Pinto Lobo, Yiwei Guan, Jingxu Guo, Alun R Coker, Marcos Roberto Lourenzoni, Maria Izabel Florindo Guedes, James S Owen, David J Abraham, Ana Cristina de Oliveira Monteiro-Moreira, Renato de Azevedo Moreira
Artocarpus incisa (breadfruit) seeds contain three different lectins (Frutalin, Frutapin and Frutackin) with distinct carbohydrate specificities. The most abundant lectin is Frutalin, an α-D-galactose-specific carbohydrate-binding glycoprotein with antitumour properties and potential for tumour biomarker discovery as already reported. Frutapin (FTP) is the second most abundant, but proved difficult to purify with very low yields and contamination with Frutalin frustrating its characterization. Here, we report for the first time high-level production and isolation of biologically-active recombinant FTP in E...
July 6, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28678900/clinical-care-of-nursing-reasoned-in-parse-contribution-in-the-transcendence-process-of-cardiac-transplantation
#6
Lia Bezerra Furtado Barros, Lúcia de Fátima da Silva, Maria Vilani Cavalcante Guedes, Vera Lúcia Mendes de Paula Pessoa
Objetivo: To identify how the clinical and educational nursing care based on the Theory of Human Becoming can contribute to the transcendence process of heart transplant patients in pursuit of good living. Method: Research-intervention developed with four heart transplant patients linked to a reference transplant hospital in Ceara. Data was collected through interviews in 2014 and analyzed using Parse's theoretical framework and pertinent literature. Resultados: Transplant patients revealed they gave living in such condition an ambiguous meaning, showing satisfaction and dissatisfaction...
June 29, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28677421/molecular-detection-of-viral-agents-in-free-ranging-and-captive-neotropical-felids-in-brazil
#7
Mariana Malzoni Furtado, Sueli Akemi Taniwaki, Iracema Nunes de Barros, Paulo Eduardo Brandão, José Luiz Catão-Dias, Sandra Cavalcanti, Laury Cullen, Claudia Filoni, Anah Tereza de Almeida Jácomo, Rodrigo Silva Pinto Jorge, Nairléia Dos Santos Silva, Leandro Silveira, José Soares Ferreira Neto
We describe molecular testing for felid alphaherpesvirus 1 (FHV-1), carnivore protoparvovirus 1 (CPPV-1), feline calicivirus (FCV), alphacoronavirus 1 (feline coronavirus [FCoV]), feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and canine distemper virus (CDV) in whole blood samples of 109 free-ranging and 68 captive neotropical felids from Brazil. Samples from 2 jaguars ( Panthera onca) and 1 oncilla ( Leopardus tigrinus) were positive for FHV-1; 2 jaguars, 1 puma ( Puma concolor), and 1 jaguarundi ( Herpairulus yagouaroundi) tested positive for CPPV-1; and 1 puma was positive for FIV...
July 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28668400/idiopathic-pulmonary-fibrosis-in-the-era-of-antifibrotic-therapy-searching-for-new-opportunities-grounded-in-evidence
#8
C Robalo-Cordeiro, P Campos, L Carvalho, A Borba, S Clemente, S Freitas, S Furtado, J M Jesus, C Leal, A Marques, N Melo, C Souto-Moura, S Neves, V Sousa, A Santos, A Morais
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease that up to now has been associated with a poor prognosis. However, the results of the INPULSIS and ASCEND trials and the approval of nintedanib and pirfenidone have marked the beginning of a new era for IPF patients. Questions remain, however. Should these drugs be used earlier? What effect will they have on more severe disease? Will their effects last beyond the trial period? This manuscript is the outcome of a multidisciplinary meeting between pulmonology, radiology, and pathology clinicians on the use of antifibrotic agents in IPF...
June 28, 2017: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/28667553/properties-and-immune-function-of-cardiac-fibroblasts
#9
Milena B Furtado, Muneer Hasham
This chapter will discuss the role of cardiac fibroblasts as a target of various immunological inputs as well as an immunomodulatory hub of the heart through interaction with immune cell types and chemokine or cytokine signaling. While the purpose of this chapter is to explore the immunomodulatory properties of cardiac fibroblasts, it is important to note that cardiac fibroblasts are not a homogeneous cell type, but have a unique embryological origin and molecular identity. Specific properties of cardiac fibroblasts may influence the way they interact with the heart microenvironment to promote healthy homeostatic function or respond to pathological insults...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28666877/microbial-analysis-of-root-canal-and-periradicular-lesion-associated-to-teeth-with-endodontic-failure
#10
R S Pereira, V A A Rodrigues, W T Furtado, S Gueiros, G S Pereira, M J Avila-Campos
The quantification of ten microorganisms at the root ends and in the surrounding periradicular lesions was performed. Thirty 3 mm samples root ends and 30 samples of the surrounding chronic periapical infection were collected during apical microsurgery. Samples were triturated, and the bacterial DNA was obtained. The bacterial quantification was performed by using the SYBR Green system. At least one microorganism was detected in all patients. In both the root end and periapical samples, Fusobacterium nucleatum (71...
June 27, 2017: Anaerobe
https://www.readbyqxmd.com/read/28659812/strength-training-decreases-inflammation-and-increases-cognition-and-physical-fitness-in-older-women-with-cognitive-impairment
#11
Matheus U Chupel, Fábio Direito, Guilherme E Furtado, Luciéle G Minuzzi, Filipa M Pedrosa, Juan C Colado, José P Ferreira, Edith Filaire, Ana M Teixeira
Introduction: Cognitive impairment that affects older adults is commonly associated with an inflammatory imbalance, resulting in decreased physical fitness. Exercise has been pointed to mitigate immunosenescence and cognitive impairment associated with aging, while increase in physical fitness. However, few studies explored the relationship between changes in cytokine concentration and improvement on cognition due to elastic band strength training. The aim of this study was to investigate the effects of strength training on pro-and anti-inflammatory cytokines, hematological markers and physical fitness of older women with cognitive impairment...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28658346/effects-of-energetic-restriction-diet-on-butyrylcholinesterase-in-obese-women-from-southern-brazil-a-longitudinal-study
#12
Willian Dos Santos, Luciane Viater Tureck, Louise Farah Saliba, Caroline Schovanz Schenknecht, Débora Scaraboto, Ricardo Lehtonen R Souza, Lupe Furtado-Alle
Objective: Butyrylcholinesterase (BChE) activity has been associated with obesity, lipid concentrations, and CHE2 locus phenotypes. This, the aim of this study was to evaluate the effects of an energetic restriction diet intervention on anthropometrical and biochemical variables and on absolute and relative BChE activity in CHE2 C5+ and CHE2 C5- individuals. Subjects and methods: One hundred eleven premenopausal obese women from Southern Brazil participated in an energetic restriction diet intervention (deficit of 2500 kJ/day) for 8 weeks...
June 26, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28658344/substernal-goiter-and-laryngopharyngeal-reflux
#13
Mariana Gonçalves Rodrigues, Vergilius José Furtado de Araujo, Leandro Luongo de Matos, Flávio Carneiro Hojaij, Cesar Augusto Simões, Vergilius José Furtado de Araujo, Daniel Marin Ramos, Renata Lorencetti Mahmoud, Letícia de Moraes Mosca, Gustavo Borges Manta, Erivelto Martinho Volpi Lenine Garcia Brandão, Claudio Roberto Cernea
Objective: This study aims to compare the prevalence of laryngopharyngeal reflux signs between two groups of patients undergoing thyroidectomy for voluminous goiter: substernal goiters and voluminous cervical goiter without thoracic extension. Subjects and methods: A retrospective case-control study was performed with data retrieved of the charts of the patients submitted to thyroidectomies occurred at a tertiary care center (Head and Neck Surgery Department, University of São Paulo Medical School) between 2010 and 2014...
June 26, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28658335/invasive-ductal-carcinoma-relationship-between-pathological-characteristics-and-the-presence-of-axillary-metastasis-in-220-cases
#14
Ranniere Gurgel Furtado DE Aquino, Paulo Henrique Diógenes Vasques, Diane Isabelle Magno Cavalcante, Ayane Layne DE Sousa Oliveira, Bruno Masato Kitagawa DE Oliveira, Luiz Gonzaga Porto Pinheiro
Objective: to analyze the relation of anatomopathological features and axillary involvement in cases of invasive ductal carcinoma. Methods: this is a cross-sectional study of 220 breast cancer patients submitted to radical mastectomy or quadrantectomy with axilar emptying, from the Mastology Service of the Assis Chateaubriand Maternity School, Ceará, Brazil. We submitted the tumors to histological processing and determined the histological (HG), tubular (TG) and nuclear (NG) grades, and the mitotic index (MI) by the classification of Scarff-Bloom-Richadson, verified the presence of angiolymphatic invasion (AI) and measured the largest tumor diameter (TD)...
March 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28649245/camelid-single-domain-antibodies-as-an-alternative-to-overcome-challenges-related-to-the-prevention-detection-and-control-of-neglected-tropical-diseases
#15
REVIEW
Carla F C Fernandes, Soraya Dos S Pereira, Marcos B Luiz, Juliana P Zuliani, Gilvan P Furtado, Rodrigo G Stabeli
Due mainly to properties such as high affinity and antigen specificity, antibodies have become important tools for biomedical research, diagnosis, and treatment of several human diseases. When the objective is to administer them for therapy, strategies are used to reduce the heterologous protein immunogenicity and to improve pharmacokinetic and pharmacodynamic characteristics. Size minimization contributes to ameliorate these characteristics, while preserving the antigen-antibody interaction site. Since the discovery that camelids produce functional antibodies devoid of light chains, studies have proposed the use of single domains for biosensors, monitoring and treatment of tumors, therapies for inflammatory and neurodegenerative diseases, drug delivery, or passive immunotherapy...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28646377/efficacy-of-an-education-course-delivered-to-community-health-workers-in-diabetes-control-a-randomized-clinical-trial
#16
Camila Furtado de Souza, Mériane Boeira Dalzochio, Alessandra Teixeira Netto Zucatti, Rosana De Nale, Marília Tavares de Almeida, Jorge Luiz Gross, Cristiane Bauermann Leitão
BACKGROUND: Community health workers are community members who provide education and care for patients for a broad range of health issues, including diabetes mellitus. However, few community health workers are trained for diabetes education and little is known about the effectiveness of their interventions. The aim of this study is to evaluate the effect of a diabetes education program delivered to community health workers in improving the metabolic control of patients with type 2 diabetes mellitus...
August 2017: Endocrine
https://www.readbyqxmd.com/read/28641954/interventional-rheumatology-the-competence-of-brazilian-rheumatologists
#17
Aline Teixeira de Landa, Jamil Natour, Rita Nely Vilar Furtado
OBJECTIVES: Describe Brazilian rheumatologists's competence in interventional rheumatology; assess the association between this ability and demographic and training variables. METHODS: A cross-sectional study with 500 Brazilian rheumatologists. Participants were assessed by self-administered questionnaire consisting of demographics, training, practice in office and knowledge in interventional rheumatology data. RESULTS: 463 participants had their data analyzed...
June 19, 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28638180/in-situ-cytokine-expression-and-morphometric-evaluation-of-total-collagen-and-collagens-type-i-and-type-iii-in-keloid-scars
#18
Isabela Rios da Silva, Luciana Colombo Rodrigues da Cunha Tiveron, Marcos Vinicius da Silva, Alberto Borges Peixoto, Carla Aparecida Xavier Carneiro, M A Dos Reis, Pedro Carvalho Furtado, Bárbara Rocha Rodrigues, Virmondes Rodrigues, Denise Bertulucci Rocha Rodrigues
Keloids are characterized by excessive collagen deposition and growth beyond the edges of the initial injury, and cytokines may be related to their formation. The objective of this study was to evaluate the collagen fibers, analyze in situ expression of cytokines in keloid lesions, and compare to the control group. Results showed that there was a predominance of women and nonwhite and direct black ancestry. Keloid showed a significant increase in total and type III collagen. Significantly, the expression of mRNA for TGF-β in keloid was increased, the expressions of IFN-γ, IFN-γR1, and IL-10 were lower, and IFN-γR1 and TNF-α had no statistical difference...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28628670/combining-ability-heritability-and-genotypic-relations-of-different-physiological-traits-in-cacao-hybrids
#19
Allan Silva Pereira, Alex-Alan Furtado de Almeida, Márcia Christina da Silva Branco, Marcio Gilberto Cardoso Costa, Dario Ahnert
Selecting parents and evaluating progenies is a very important step in breeding programs and involves approaches such as understanding the initial stages of growth and characterizing the variability among genotypes for different parameters, such as physiological, growth, biomass partitioning and nutrient translocation to the aerial part. In these cases, facilitating tools can be used to understand the involved gene dynamics, such as diallel crosses and genetic and phenotypic correlations. Our main hypothesis is that the contrasting phenotypes of these parental genotypes of cocoa used are due to genetic factors, and progenies derived from crosses of these parental genotypes are useful for breeding programs related to plant architecture, physiological parameters and translocation of mineral nutrients...
2017: PloS One
https://www.readbyqxmd.com/read/28614756/photosynthetic-antioxidative-molecular-and-ultrastructural-responses-of-young-cacao-plants-to-cd-toxicity-in-the-soil
#20
Romária Pereira de Araújo, Alex-Alan Furtado de Almeida, Lidiane Silva Pereira, Pedro A O Mangabeira, José Olimpio Souza, Carlos P Pirovani, Dário Ahnert, Virupax C Baligar
Cadmium (Cd) is a highly toxic metal for plants, even at low concentrations in the soil. The annual production of world cocoa beans is approximately 4 million tons. Most of these fermented and dried beans are used in the manufacture of chocolate. Recent work has shown that the concentration of Cd in these beans has exceeded the critical level (0.6mgkg(-1) DM). The objective of this study was to evaluate the toxicity of Cd in young plants of CCN 51 cacao genotype grown in soil with different concentrations of Cd (0, 0...
June 10, 2017: Ecotoxicology and Environmental Safety
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