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https://www.readbyqxmd.com/read/29786499/scheffersomyces-stambukii-f-a-sp-nov-a-d-xylose-fermenting-species-isolated-from-rotting-wood
#1
Mariana R Lopes, Thiago M Batista, Glória R Franco, Lucas R Ribeiro, Ana R O Santos, Carolina Furtado, Rennan G Moreira, Aristóteles Goes-Neto, Marcos J S Vital, Luiz H Rosa, Marc-André Lachance, Carlos A Rosa
Two isolates representing a new species of Scheffersomyces were isolated from rotting wood samples collected in an Amazonian forest ecosystem in Brazil. Analysis of the sequences of the D1/D2 domains showed that this new species is phylogenetically related to Scheffersomyces NYMU 15730, a species without a formal description, and the two are in an early emerging position with respect to the xylose-fermenting subclade containing Scheffersomyces titanus and Scheffersomyces stipitis. Phylogenomic analyses using 474 orthologous genes placed the new species in an intermediary position between Scheffersomyces species and the larger genus Spathaspora and the Candida albicans/Lodderomyces clade...
May 22, 2018: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29779965/wheat-seed-transcriptome-reveals-genes-controlling-key-traits-for-human-preference-and-crop-adaptation
#2
REVIEW
Robert J Henry, Agnelo Furtado, Parimalan Rangan
Analysis of the transcriptome of the developing wheat grain has associated expression of genes with traits involving production (e.g. yield) and quality (e.g. bread quality). Photosynthesis in the grain may be important in retaining carbon that would be lost in respiration during grain filling and may contribute to yield in the late stages of seed formation under warm and dry environments. A small number of genes have been identified as having been selected by humans to optimize the performance of wheat for foods such as bread...
May 17, 2018: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/29770233/metastasis-to-paranasal-sinuses-from-carcinoma-of-prostate-report-of-a-case-and-review-of-the-literature
#3
Elio Bittar Barbosa, Evaldo César Macau Furtado Ferreira, Fernanda Viviane Mariano, Albina Messias de Almeida Milani Altemani, Emerson Taro Inoue Sakuma, Eulalia Sakano
Metastasis from distant primary tumors is extremely rare in the paranasal sinuses with few hundred cases in the literature. Metastatic carcinoma of the prostate is even rarer, despite being one of the most common tumors, with only 24 cases published. In this article, we report a case of a 58-year-old male presenting with epistaxis and nasal obstruction as initial symptoms of a metastatic prostate carcinoma in the ethmoid cells and maxillary sinus.
2018: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/29769727/microbial-signals-drive-pre-leukaemic-myeloproliferation-in-a-tet2-deficient-host
#4
Marlies Meisel, Reinhard Hinterleitner, Alain Pacis, Li Chen, Zachary M Earley, Toufic Mayassi, Joseph F Pierre, Jordan D Ernest, Heather J Galipeau, Nikolaus Thuille, Romain Bouziat, Manuel Buscarlet, Daina L Ringus, Yitang Wang, Ye Li, Vu Dinh, Sangman M Kim, Benjamin D McDonald, Matthew A Zurenski, Mark W Musch, Glaucia C Furtado, Sergio A Lira, Gottfried Baier, Eugene B Chang, A Murat Eren, Christopher R Weber, Lambert Busque, Lucy A Godley, Elena F Verdú, Luis B Barreiro, Bana Jabri
Somatic mutations in tet methylcytosine dioxygenase 2 (TET2), which encodes an epigenetic modifier enzyme, drive the development of haematopoietic malignancies1-7 . In both humans and mice, TET2 deficiency leads to increased self-renewal of haematopoietic stem cells with a net developmental bias towards the myeloid lineage1,4,8,9 . However, pre-leukaemic myeloproliferation (PMP) occurs in only a fraction of Tet2-/- mice8,9 and humans with TET2 mutations1,3,5-7 , suggesting that extrinsic non-cell-autonomous factors are required for disease onset...
May 16, 2018: Nature
https://www.readbyqxmd.com/read/29753828/physiological-ultrastructural-biochemical-and-molecular-responses-of-young-cocoa-plants-to-the-toxicity-of-cr-iii-in-soil
#5
Junea Leandro do Nascimento, Alex-Alan Furtado de Almeida, Joedson P Barroso, Pedro A O Mangabeira, Dário Ahnert, Artur G R Sousa, José Vitor S Silva, Virupax C Baligar
The objective of this study was to evaluate Cr toxicity in young plants of the CCN 51 Theobroma cacao genotype at different concentrations of Cr3+ in the soil (0, 100, 200, 400 and 600 mg kg-1 ) through physiological, ultrastructural, antioxidant and molecular changes. Doses of 400 and 600 mg Cr3+ kg-1 soil severely affected foliar gas exchange, promoted by damages in photosynthetic machinery evidenced by the decrease in CO2 fixation. Decreased expression of psbA and psbO genes, changes in enzymatic activity and lipid peroxidation also affected leaf gas exchange...
May 10, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29753711/chloroplast-phylogeny-of-aa-genome-rice-species
#6
Ali Mohammad Moner, Agnelo Furtado, Robert J Henry
Whole chloroplast genome sequence analysis of 58 wild and domesticated rice samples was used to investigate their phylogeny providing more detail on the biogeography of the major groups of wild A genome rices globally. An optimized chloroplast assembly method was developed and applied to extracting high quality whole chloroplast genome sequences from shot gun whole DNA sequencing data. Forty complete high quality chloroplast genome sequences were assembled (including; temperate japonica, tropical japonica and aus)...
May 10, 2018: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29750153/health-related-quality-of-life-in-pulmonary-hypertension-and-its-clinical-correlates-a-cross-sectional-study
#7
Abílio Reis, Mário Santos, Margarida Vicente, Inês Furtado, Célia Cruz, Alzira Melo, Luísa Carvalho, Fabienne Gonçalves, Pedro Sa-Couto, Luís Almeida
Background: Health-related quality of life (HRQoL) impairment is common in pulmonary hypertension (PH), but its clinical predictors are not well established. This study aims to characterize the HRQoL of patients with pulmonary arterial hypertension (PAH) and other precapillary forms of PH (pcPH) and to explore its clinical correlates. Materials and Methods: A cross-sectional, observational study of patients with documented PAH and other forms of pcPH. Patients completed two patient-reported outcome measures (PROM): Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and Nottingham Health Profile (NHP)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29746364/management-and-outcome-of-pediatric-patients-with-transient-small-bowel-small-bowel-intussusception
#8
Jennifer E Melvin, Noel S Zuckerbraun, Chijindu R Nworgu, Kevin P Mollen, Andre D Furtado, Mioara D Manole
OBJECTIVE: The aim of this study was to assess the management and outcomes of healthy pediatric patients diagnosed radiologically with transient and benign small bowel-small bowel intussusception (SB-SBI). METHODS: Retrospective cohort study of healthy patients 0 to 18 years of age who presented to a children's hospital emergency department from January 1, 2005, to June 30, 2015, and had transient and benign SB-SBI characterized by spontaneous resolution (ie, transient), diameter of less than 2...
May 5, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29742232/can-low-fusing-glass-application-affect-the-marginal-misfit-and-bond-strength-of-y-tzp-crowns
#9
Monize Carelli Felipe Antunes, Jean Soares Miranda, Ronaldo Luís Almeida de Carvalho, Rodrigo Furtado de Carvalho, Estevão Tomomitsu Kimpara, Rodrigo Othávio de Assunção E Souza, Fabíola Pessôa Pereira Leite
To evaluate the effect of different surface treatments on the marginal misfit and retentive strength between Y-TZP crowns and an epoxy resin. Forty (40) epoxy resin (G10) abutments (height: 5mm, conicity: 60, finish line: large chamfer) with equal dimensions were milled and included in polyurethane to simulate the periodontal ligament. Next, 40 Y-TZP crowns (thickness: 1mm) were milled (Cerec in Lab) and randomly divided into four groups (n=10) according to the surface treatment: GS(glaze spray), GP(glaze powder/liquid), P(zirconia primer) and RS(tribochemical silica coating)...
2018: Brazilian Oral Research
https://www.readbyqxmd.com/read/29740101/tissue-distribution-and-cell-tropism-of-brucella-canis-in-naturally-infected-canine-foetuses-and-neonates
#10
Tayse Domingues de Souza, Tatiane Furtado de Carvalho, Juliana Pinto da Silva Mol, João Vítor Menezes Lopes, Monique Ferreira Silva, Tatiane Alves da Paixão, Renato Lima Santos
Brucella canis infection is an underdiagnosed zoonotic disease. Knowledge about perinatal brucellosis in dogs is extremely limited, although foetuses and neonates are under risk of infection due to vertical transmission. In this study, immunohistochemistry was used to determine tissue distribution and cell tropism of B. canis in canine foetuses and neonates. Diagnosis of B. canis in tissues of naturally infected pups was based on PCR and sequencing of amplicons, bacterial isolation, and immunohistochemistry, whose specificity was confirmed by laser capture microdissection...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29737321/resection-of-a-giant-nonparasitic-splenic-cyst-by-minilaparoscopy
#11
Gustavo Lopes de Carvalho, Gustavo Henrique Belarmino de Góes, Raimundo Hugo Matias Furtado, Raquel Nogueir Cordeiro, Marianna de Castro Araújo Lessa
A female patient, 20 years old, with a history of a progressive increase in abdominal volume on the left side, starting 3 years ago, with no associated symptoms and no history of trauma. Ultrasonography and a computed tomography scan of the abdomen were performed, which revealed a large splenomegaly, and a partial minilaparoscopic splenectomy was indicated. We opted for unroofing of the cyst, and the procedure was uneventful, with a total surgical time of 47 min. The patient progressed clinically well, without abdominal pain, being discharged on the 2nd post-operative day...
May 4, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29734573/hyperbaric-oxygen-therapy-as-treatment-for-bilateral-arm-compartment-syndrome-after-crossfit-case-report-and-literature-review
#12
Adriano Fernando Mendes, José da Mota Neto, Erica Maciel Heringer, Leandro Furtado de Simoni, Diego Demolinari Pires, Pedro José Labronici
Introduction: CrossFit is a physical fitness program characterized by high-intensity workouts that can be associated with serious injury. Acute compartment syndrome in the upper limbs is a rare occurrence. It may occur after intense physical exercise, and its usual treatment is surgical. Hyperbaric oxygen therapy is a treatment described as adjunctive in cases of compartmental syndrome. Presentation: We describe the case of a CrossFit practitioner who, after intense training, developed progressive symptoms of rhabdomyolysis and acute bilateral arm compartment syndrome, who was successfully treated with hyperbaric oxygen therapy and required no fasciotomy as surgical treatment...
March 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29734405/effects-of-cryolipolysis-on-abdominal-adiposity-of-women
#13
P F Meyer, A C G Furtado, S F T Morais, L G de Araujo Neto, R M Valentim da Silva, R Marcel, M L Medeiros, C A Maciel de Queiroz
  BACKGROUND: The cryolipolysis is on the spotlight as a non-invasive method which reduces fat layer thickness with no damage to surrounding tissues. OBJECTIVE: This study aims to verify the effectiveness of cryolipolysis in the reduction of localized adiposity in women. MATERIALS AND METHODS: This is an experimental study, without a control group, with pre- and post- treatment evaluation through a single application on the lower abdominal area. SETTING: Research conducted in the period from July to December 2015 at the University Potiguar...
September 2017: Cryo Letters
https://www.readbyqxmd.com/read/29729499/examining-predictors-of-help-seeking-behaviours-in-patients-with-mood-and-anxiety-symptoms
#14
A Fine, K Nasiri, K Fotinos, L Anand, M Furtado, R S Armata, K Badali, J Mincer, M Mincer, I Epstein, C Cameron, A Guthrie, S Cook, B Laidlaw, T Sternat, M A Katzman
Relatively little is known about individual characteristics that factor into the decision to seek help for mood and anxiety symptoms. The current study was undertaken in order to examine factors that predict the likelihood of seeking help for mood and anxiety symptoms amongst a clinical population. Patients (N = 278) referred to a tertiary care clinic in Toronto, Canada were asked about their help-seeking behaviours (HSB) through initial intake assessments and self-administered questionnaires, including the Beck Anxiety Inventory, Anxiety Sensitivity Index, Intolerance of Uncertainty Scale, and Beck Depression Inventory-II...
April 24, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29721304/diversity-and-evolution-of-rice-progenitors-in-australia
#15
Ali M Moner, Agnelo Furtado, Ian Chivers, Glen Fox, Darren Crayn, Robert J Henry
In the thousands of years of rice domestication in Asia, many useful genes have been lost from the gene pool. Wild rice is a key source of diversity for domesticated rice. Genome sequencing has suggested that the wild rice populations in northern Australia may include novel taxa, within the AA genome group of close (interfertile) wild relatives of domesticated rice that have evolved independently due to geographic separation and been isolated from the loss of diversity associated with gene flow from the large populations of domesticated rice in Asia...
April 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29713995/full-protection-against-soman-induced-seizures-and-brain-damage-by-ly293558-and-caramiphen-combination-treatment-in-adult-rats
#16
James P Apland, Vassiliki Aroniadou-Anderjaska, Taiza H Figueiredo, Marcio De Araujo Furtado, Maria F M Braga
Acute exposure to nerve agents induces status epilepticus (SE), which causes brain damage or death. LY293558, an antagonist of AMPA and GluK1 kainate receptors is a very effective anticonvulsant and neuroprotectant against soman; however, some neuronal damage is still present after treatment of soman-exposed rats with LY293558. Here, we have tested whether combining LY293558 with an NMDA receptor antagonist can eliminate the residual damage. For this purpose, we chose caramiphen (CRM), an antimuscarinic compound with NMDA receptor antagonistic properties...
April 30, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29713294/characteristics-and-pathways-of-long-stay-patients-in-high-and-medium-secure-settings-in-england-a-secondary-publication-from-a-large-mixed-methods-study
#17
Birgit A Völlm, Rachel Edworthy, Nick Huband, Emily Talbot, Shazmin Majid, Jessica Holley, Vivek Furtado, Tim Weaver, Ruth McDonald, Conor Duggan
Background: Many patients experience extended stays within forensic care, but the characteristics of long-stay patients are poorly understood. Aims: To describe the characteristics of long-stay patients in high and medium secure settings in England. Method: Detailed file reviews provided clinical, offending and risk data for a large representative sample of 401 forensic patients from 2 of the 3 high secure settings and from 23 of the 57 medium secure settings in England on 1 April 2013. The threshold for long-stay status was defined as 5 years in medium secure care or 10 years in high secure care, or 15 years in a combination of high and medium secure settings...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29709373/rosette-forming-glioneural-tumor-in-the-tectal-plate-endoscopic-diagnosis-and-conservative-management
#18
D Kitumba, R Reinas, R Santos, A Furtado, L Mascarenhas, M Resende
We present the case of a 29 year-old male with a tumor involving the mesencephalic tectum with associated hydrocephalus. Third ventriculocisternostomy was performed along with endoscopic biopsy; this provided adequate sampling of the tumor and enabled diagnosis of rosette-forming glioneural tumor (RGNT). The patient was followed for 48 months without progression of the disease. We review the features of the previous eight cases described in the literature and discuss the advantages of a minimally invasive approach and conservative management...
April 27, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29698836/system-for-informatics-in-the-molecular-pathology-laboratory-simpl-an-open-source-end-to-end-solution-for-next-generation-sequencing-clinical-data-management
#19
Wenjun Kang, Sabah Kadri, Rutika Puranik, Michelle N Wurst, Sushant A Patil, Ibro Mujacic, Sonia Benhamed, Nifang Niu, Chao Jie Zhen, Bekim Ameti, Bradley C Long, Filipo Galbo, David Montes, Crystal Iracheta, Venessa L Gamboa, Daisy Lopez, Michael Yourshaw, Carolyn A Lawrence, Dara L Aisner, Carrie Fitzpatrick, Megan E McNerney, Y Lynn Wang, Jorge Andrade, Samuel L Volchenboum, Larissa V Furtado, Lauren L Ritterhouse, Jeremy P Segal
Next-generation sequencing (NGS) diagnostic assays are increasingly becoming the standard of care in oncology practice. As the scale of an NGS laboratory grows, management of these assays requires organizing large amounts of information, including patient data, laboratory processes, genomic data, as well as variant interpretation and reporting. Although several Laboratory Information Systems (LIS) and/or Laboratory Information Management Systems (LIMS) are commercially available, they may not meet all of the needs of a given laboratory, in addition to being frequently cost prohibitive...
April 23, 2018: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/29693261/fecal-glucocorticoid-metabolites-and-assay-validation-stress-response-evaluation-in-captive-brown-howler-monkeys-alouatta-clamitans
#20
Thais Eleonora Madeira Buti, Tatiana Kugelmeier, Gisela Sobral, Priscila Viau Furtado, Dafne do Valle Dutra de Andrade Neves, Claudio Alvarenga de Oliveira
BACKGROUND: The advent of non-invasive methods provides a powerful alternative to stress studies as the use of stressful handling techniques is no longer needed. However, many factors influence hormone metabolism such as sex, diet, and metabolic rate. Thus, validation should be species- and matrix-specific. METHODS: To assess stress response in brown howler monkeys Alouatta clamitans, we adopted an ACTH challenge test and parallelism to provide physiological and laboratorial validation...
April 25, 2018: Journal of Medical Primatology
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