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https://www.readbyqxmd.com/read/28628670/combining-ability-heritability-and-genotypic-relations-of-different-physiological-traits-in-cacao-hybrids
#1
Allan Silva Pereira, Alex-Alan Furtado de Almeida, Márcia Christina da Silva Branco, Marcio Gilberto Cardoso Costa, Dario Ahnert
Selecting parents and evaluating progenies is a very important step in breeding programs and involves approaches such as understanding the initial stages of growth and characterizing the variability among genotypes for different parameters, such as physiological, growth, biomass partitioning and nutrient translocation to the aerial part. In these cases, facilitating tools can be used to understand the involved gene dynamics, such as diallel crosses and genetic and phenotypic correlations. Our main hypothesis is that the contrasting phenotypes of these parental genotypes of cocoa used are due to genetic factors, and progenies derived from crosses of these parental genotypes are useful for breeding programs related to plant architecture, physiological parameters and translocation of mineral nutrients...
2017: PloS One
https://www.readbyqxmd.com/read/28614756/photosynthetic-antioxidative-molecular-and-ultrastructural-responses-of-young-cacao-plants-to-cd-toxicity-in-the-soil
#2
Romária Pereira de Araújo, Alex-Alan Furtado de Almeida, Lidiane Silva Pereira, Pedro A O Mangabeira, José Olimpio Souza, Carlos P Pirovani, Dário Ahnert, Virupax C Baligar
Cadmium (Cd) is a highly toxic metal for plants, even at low concentrations in the soil. The annual production of world cocoa beans is approximately 4 million tons. Most of these fermented and dried beans are used in the manufacture of chocolate. Recent work has shown that the concentration of Cd in these beans has exceeded the critical level (0.6mgkg(-1) DM). The objective of this study was to evaluate the toxicity of Cd in young plants of CCN 51 cacao genotype grown in soil with different concentrations of Cd (0, 0...
June 10, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28611166/cytomegalovirus-duodenitis-in-immunocompetent-patients-what-else-should-we-look-for
#3
Dalila Costa, Dália Fernandes, Antónia Furtado, Andre Santa Cruz
Cytomegalovirus (CMV) infection is a well-recognised complication of immunodeficiency, although the burden of CMV disease in immunocompetent adults is still unknown. We present the case of a 54-year-old male patient admitted due to severe diarrhoea, epigastric pain and fever. Initial diagnostic workup revealed pericardial and pleural effusion, enlarged abdominal lymph nodes and mild elevation of liver enzymes. CMV serology was IgM positive, and upper endoscopy revealed proximal enteritis. Histology and immunohistochemistry of duodenal samples confirmed CMV disease...
June 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28607556/factors-affecting-the-periapical-status-of-root-filled-canals-a-cross-sectional-study-at-the-undergraduate-level
#4
George Moreira Costa, Suelleng Maria Santos Soares, Paula Cristina Pelli Paiva, Flaviana Dornela Verli, Patrícia Furtado Gonçalves, Sangela Maria da Silva Pereira, Rudys Rodolfo De Jesus Tavarez, Janir Alves Soares, Etevaldo Matos Maia Filho
OBJECTIVE: The aim was to evaluate the influence of multiple factors on the periapical status of endodontically treated (ET) teeth. METHODS: The patients were clinically and radiographically reevaluated after root canal therapy. The quality of the root-filled canals, coronal restorations, intraradicular posts, dental caries, and periodontal parameters were associated with the teeth's periapical status. RESULTS: The 122 patients provided 154 ET teeth; 97...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28606528/molecular-structures-and-properties-of-starches-of-australian-wild-rice
#5
Tiparat Tikapunya, Wei Zou, Wenwen Yu, Prudence O Powell, Glen P Fox, Agnelo Furtado, Robert J Henry, Robert G Gilbert
Australian wild rices have significant genetic differences from domesticated rices, which might provide rices with different starch molecular structure and thus different functional properties. Molecular structure, gelatinization properties, and pasting behaviours of starch of three Australian wild rices (Oryza australiensis, taxa A (O. rufipogon like) and taxa B (O. meridionalis like)) were determined and compared to domesticated indica and japonica rice. These had higher amylose content, more shorter amylose chains and fewer short amylopectin chains, resulted in a high gelatinization temperature in these wild rices...
September 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28596802/nursing-diagnoses-in-adult-elderly-patients-undergoing-outpatient-antineoplastic-chemotherapy-a-review
#6
REVIEW
Rafael Tavares Jomar, Rebeca Anselmo Furtado Gomes, Dayana Carvalho Leite, Helena Ferraz Gomes, Ellen Marcia Peres, Eugenio Fuentes Perez Junior
OBJECTIVE: To search in the scientific literature for nursing diagnoses identified in adult/elderly patients undergoing antineoplastic chemotherapy in an outpatient setting. METHODS: Review of studies published in Portuguese, English, or Spanish which were searched in five electronic databases in March 2016, using the descriptors nursing process, nursing diagnosis, neoplasms, drug therapy and hospital outpatient clinic. RESULTS: In the four studies selected for review, 40 nursing diagnoses were identified, namely unbalanced nutrition, less than body requirements, risk of deficient fluid volume, diarrhoea, fatigue, impaired home maintenance, deficient knowledge, disturbed body image, interrupted family processes, ineffective sexuality pattern, anxiety, powerlessness, fear, readiness for enhanced religiosity, risk of infection, impaired dentition, risk of impaired skin integrity, acute pain, and nausea...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28594461/evaluation-of-a-composite-gel-alanine-phantom-on-an-end-to-end-test-to-treat-multiple-brain-metastases-by-a-single-isocenter-vmat-technique
#7
Juliana Fernandes Pavoni, Wellington Furtado Pimenta Neves, Matheus Antonio da Silveira, Cecília Maria Kalil Haddad, Oswaldo Baffa
PURPOSE: This work aims to evaluate the application of a cylindrical phantom made of dosimetric gel containing alanine pellets distributed inside the gel volume during an end-to-end test of a single isocenter VMAT for simultaneous treatment of multiple brain metastases. The evaluation is based on the comparison of the results obtained with the composite phantom with the treatment planning system (TPS) dose distribution validated by using the clinical conventional quality control with point and planar dose measurements...
June 8, 2017: Medical Physics
https://www.readbyqxmd.com/read/28589027/developing-a-globally-applicable-evidence-informed-competency-framework-to-support-capacity-strengthening-in-clinical-research
#8
Amélie Julé, Tamzin Furtado, Liam Boggs, Francois van Loggerenberg, Victoria Ewing, Manhaz Vahedi, Pascal Launois, Trudie Lang
Capacity development for clinical research is held back by a lack of recognition for the skills acquired through involvement in clinical trials and in other varied types of global health research studies. Although some competency frameworks and associated recognised career pathways exist for different clinical research roles, they mostly apply to a single role or study setting. Our experience supports the need for an integrated approach, looking at the many roles in parallel and at all types of clinical research beyond trials...
March 2017: BMJ Global Health
https://www.readbyqxmd.com/read/28581151/gas-phase-fragmentation-of-protonated-piplartine-and-its-fungal-metabolites-using-tandem-mass-spectrometry-and-computational-chemistry
#9
E A da Silva-Junior, C R Paludo, D R Gouvea, M J Kato, N A J C Furtado, N P Lopes, R Vessecchi, M T Pupo
Piplartine, an alkaloid produced by plants in the genus Piper, displays promising anticancer activity. Understanding the gas-phase fragmentation of piplartine by electrospray ionization tandem mass spectrometry can be a useful tool to characterize biotransformed compounds produced by in vitro and in vivo metabolism studies. As part of our efforts to understand natural product fragmentation in electrospray ionization tandem mass spectrometry, the gas-phase fragmentation of piplartine and its two metabolites 3,4-dihydropiplartine and 8,9-dihydropiplartine, produced by the endophytic fungus Penicillium crustosum VR4 biotransformation were systematically investigated...
June 5, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28560893/physical-fitness-and-frailty-syndrome-in-institutionalized-older-women
#10
Guilherme Furtado, Miguel Patrício, Marisa Loureiro, Ana Maria Teixeira, José Pedro Ferreira
Associations between frailty and physical-functional fitness (PFF) indicators in frail women over 65 years of age remain largely unexplored. This study analyzed the relationship between frailty syndrome (FS) and PFF indicators and assessed how the latter might predict the former. Participants were 119 elderly women (81.96 ± 7.89 years) recruited from four social and healthcare centers. PFF was assessed through muscle strength tests of upper and lower limbs, endurance, agility-dynamic balance, flexibility, and body composition...
January 1, 2017: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/28560845/spinocerebellar-ataxia-type-10-common-haplotype-and-disease-progression-rate-in-peru-and-brazil
#11
T C Gheno, G V Furtado, J A M Saute, K C Donis, A M V Fontanari, V E Emmel, J L Pedroso, O Barsottini, C Godeiro-Junior, H van der Linden, E Ternes Pereira, V P Cintra, W Marques, R M de Castilhos, I Alonso, J Sequeiros, M Cornejo-Olivas, P Mazzetti, V B Leotti, L B Jardim, M L Saraiva-Pereira
BACKGROUND AND PURPOSE: Spinocerebellar ataxia type 10 is a neurodegenerative disorder that is due to an expanded ATTCT repeat tract in the ATXN10 gene. Our aim was to describe clinical characteristics and intragenic haplotypes of patients with spinocerebellar ataxia type 10 from Brazil and Peru. METHODS: Expanded alleles were detected by repeat-primed polymerase chain reaction. Disease progression was measured by the Scale for the Assessment and Rating of Ataxia, and the Neurological Examination Score for Spinocerebellar Ataxias when possible...
May 31, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28558076/functional-effects-of-hyperthyroidism-on-cardiac-papillary-muscle-in-rats
#12
Fabricio Furtado Vieira, Robson Ruiz Olivoto, Priscyla Oliveira da Silva, Julio Cesar Francisco, Rosalvo Tadeu Hochmuller Fogaça
BACKGROUND: Hyperthyroidism is currently recognized to affect the cardiovascular system, leading to a series of molecular and functional changes. However, little is known about the functional influence of hyperthyroidism in the regulation of cytoplasmic calcium and on the sodium/calcium exchanger (NCX) in the cardiac muscle. OBJECTIVES: To evaluate the functional changes in papillary muscles isolated from animals with induced hyperthyroidism. METHODS: We divided 36 Wistar rats into a group of controls and another of animals with hyperthyroidism induced by intraperitoneal T3 injection...
December 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28553114/ravuconazole-self-emulsifying-delivery-system-in-vitro-activity-against-trypanosoma-cruzi-amastigotes-and-in-vivo-toxicity
#13
Pollyanna Álvaro Spósito, Ana Lia Mazzeti, Caroline de Oliveira Faria, Julio A Urbina, Gwenaelle Pound-Lana, Maria Terezinha Bahia, Vanessa Furtado Mosqueira
Self-emulsifying drug delivery systems (SEDDSs) are lipid-based anhydrous formulations composed of an isotropic mixture of oil, surfactant, and cosurfactants usually presented in gelatin capsules. Ravuconazole (Biopharmaceutics Classification System [BCS] Class II) is a poorly water-soluble drug, and a SEDDS type IIIA was designed to deliver it in a predissolved state, improving dissolution in gastrointestinal fluids. After emulsification, the droplets had mean hydrodynamic diameters <250 nm, zeta potential values in the range of -45 mV to -57 mV, and showed no signs of ravuconazole precipitation...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28551725/colorectal-cancer-molecular-profiling-from-ihc-to-ngs-in-search-of-optimal-algorithm
#14
Larissa V Furtado, Wade S Samowitz
Advances in defining the mutational landscape of colorectal cancer (CRC) over the past decades have revolutionized the molecular understanding and clinical testing algorithms for this disease. Mutation testing is standard of care for the work-up of CRCs. This review focuses on the current indications and strategies for molecular testing in CRC and discusses the potential changes in CRC testing approach associated with the emerging clinical application of genomic-based technologies.
May 27, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28549322/high-throughput-continuous-production-of-liposomes-using-hydrodynamic-flow-focusing-microfluidic-devices
#15
Mariano Michelon, Davi Rocha Bernardes Oliveira, Guilherme de Figueiredo Furtado, Lucimara Gaziola de la Torre, Rosiane Lopes Cunha
The microfluidic hydrodynamic flow-focusing is a simple technique for nanoscale liposome formation that provides several advantages compared to the traditional manufacturing techniques. This work aimed to perform a systematic study of the liposome formation using planar microfluidic devices with different channel aspect-ratios, as an alternative to enhance the throughput of liposome synthesis. In general, liposomes with a low polydispersity and a precise control of the size were successfully produced from alteration of the flow rate ratio and channel aspect-ratio...
May 11, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28544246/liver-transplantation-for-colo-rectal-liver-metastasis-survival-without-recurrence-can-be-achieved
#16
Christian Toso, Hugo Pinto Marques, Axel Andres, Francisco Castro Sousa, René Adam, Antonio Kalil, Pierre-Alain Clavien, Emanuel Furtado, Eduardo Barroso, Henri Bismuth
No abstract text is available yet for this article.
May 22, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28532419/a-survey-of-the-complex-transcriptome-from-the-highly-polyploid-sugarcane-genome-using-full-length-isoform-sequencing-and-de-novo-assembly-from-short-read-sequencing
#17
Nam V Hoang, Agnelo Furtado, Patrick J Mason, Annelie Marquardt, Lakshmi Kasirajan, Prathima P Thirugnanasambandam, Frederik C Botha, Robert J Henry
BACKGROUND: Despite the economic importance of sugarcane in sugar and bioenergy production, there is not yet a reference genome available. Most of the sugarcane transcriptomic studies have been based on Saccharum officinarum gene indices (SoGI), expressed sequence tags (ESTs) and de novo assembled transcript contigs from short-reads; hence knowledge of the sugarcane transcriptome is limited in relation to transcript length and number of transcript isoforms. RESULTS: The sugarcane transcriptome was sequenced using PacBio isoform sequencing (Iso-Seq) of a pooled RNA sample derived from leaf, internode and root tissues, of different developmental stages, from 22 varieties, to explore the potential for capturing full-length transcript isoforms...
May 22, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28523408/genetics-and-epigenetics-of-varicocele-pathophysiology-an-overview
#18
REVIEW
Viviane Paiva Santana, Cristiana Libardi Miranda-Furtado, Flavia Gaona de Oliveira-Gennaro, Rosana Maria Dos Reis
Varicocele is found in approximately 20% of adults and adolescents and in 19-41% of men seeking treatment for infertility. It is associated with a decrease in sperm count as well as sperm motility and morphology. The currently accepted description of the pathophysiology of varicocele does not explain all its clinical manifestations; therefore, other factors such as genetic and epigenetic changes, associated with the environment, might be involved in causing infertility and decrease in sperm quality. It has been reported that the varicocele-induced deterioration of testicular function is progressive and interferes with fertility; hence, early and efficient assessment of the genetic manifestations in patients would be important for developing future medical interventions...
May 18, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28522704/draft-genome-sequence-of-metschnikowia-australis-strain-ufmg-cm-y6158-an-extremophile-marine-yeast-endemic-to-antarctica
#19
Thiago M Batista, Heron O Hilário, Rennan G Moreira, Carolina Furtado, Valéria M Godinho, Luiz H Rosa, Glória R Franco, Carlos A Rosa
Here we report the draft genome sequence of Metschnikowia australis strain UFMG-CM-Y6158, a yeast endemic to Antarctica. We isolated the strain from the marine seaweed Acrosiphonia arcta (Chlorophyta). The genome is 14.3 Mb long and contains 4,442 predicted protein-coding genes.
May 18, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28520887/apolipoprotein-c-iii-and-high-density-lipoprotein-subspecies-defined-by-apolipoprotein-c-iii-in-relation-to-diabetes-risk
#20
Sarah A Aroner, Ming Yang, Junlong Li, Jeremy D Furtado, Frank M Sacks, Anne Tjønneland, Kim Overvad, Tianxi Cai, Majken K Jensen
Apolipoprotein C-III (apoC-III) is a potential novel biomarker that may play an important role in the pathogenesis of diabetes, particularly when present on high-density lipoprotein (HDL). In a case-cohort design among 3,101 non-cases and 434 incident diabetes cases occurring before 2007 in the Danish Diet, Cancer, and Health study, we examined associations of baseline (1993-1997) plasma concentrations of apoC-III and subspecies of HDL defined by the presence or absence of apoC-III with risk of diabetes using Cox regression...
May 18, 2017: American Journal of Epidemiology
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