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Jessica L Cohen

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https://www.readbyqxmd.com/read/28511192/individual-variation-in-hunger-energy-intake-and-ghrelin-responses-to-acute-exercise
#1
James A King, Kevin Deighton, David R Broom, Lucy K Wasse, Jessica A Douglas, Stephen F Burns, Philip A Cordery, Emily S Petherick, Rachel L Batterham, Fernanda R Goltz, Alice E Thackray, Thomas Yates, David J Stensel
PURPOSE: This study aimed to characterize the immediate and extended effect of acute exercise on hunger, energy intake, and circulating acylated ghrelin concentrations using a large data set of homogenous experimental trials and to describe the variation in responses between individuals. METHODS: Data from 17 of our group's experimental crossover trials were aggregated yielding a total sample of 192 young, healthy males. In these studies, single bouts of moderate to high-intensity aerobic exercise (69% ± 5% V˙O2 peak; mean ± SD) were completed with detailed participant assessments occurring during and for several hours postexercise...
June 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28481642/micronutrient-therapy-for-violent-and-aggressive-male-youth-an-open-label-trial
#2
Jessica L Hambly, Kelly Francis, Sohil Khan, Kristen S Gibbons, William J Walsh, Brett Lambert, Chris Testa, Alison Haywood
OBJECTIVES: Pharmacotherapy for problematic aggressive and violent behavior disorders in male children and adolescents is associated with significant adverse events. Treatments with more acceptable risk-benefit ratios are critically needed. Micronutrient intervention will be investigated as an alternative to bridge the therapeutic gap in the management of these behaviors. METHODS: Males aged 4-14 who displayed ongoing violent and aggressive behaviors received micronutrient intervention containing alpha-tocopherol (vitamin E), ascorbic acid (vitamin C), biotin, chromium, pyridoxal-5-phosphate (P5P), pyridoxine (vitamins B6), selenium, and zinc, in a 16-week open-label trial...
May 8, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28335910/management-strategies-for-cln2-disease
#3
REVIEW
Ruth E Williams, Heather R Adams, Martin Blohm, Jessica L Cohen-Pfeffer, Emily de Los Reyes, Jonas Denecke, Kristen Drago, Charlie Fairhurst, Margie Frazier, Norberto Guelbert, Szilárd Kiss, Annamaria Kofler, John A Lawson, Lenora Lehwald, Mary-Anne Leung, Svetlana Mikhaylova, Jonathan W Mink, Miriam Nickel, Renée Shediac, Katherine Sims, Nicola Specchio, Meral Topcu, Ina von Löbbecke, Andrea West, Boris Zernikow, Angela Schulz
CLN2 disease (neuronal ceroid lipofuscinosis type 2) is a rare, autosomal recessive, pediatric-onset, rapidly progressive neurodegenerative lysosomal storage disorder caused by tripeptidyl peptidase 1 (TPP1) enzyme deficiency, and is characterized by language delay, seizures, rapid cognitive and motor decline, blindness, and early death. No management guidelines exist and there is a paucity of published disease-specific evidence to inform clinical practice, which currently draws upon experience from the field of childhood neurodisability...
April 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28285739/neuropsychiatric-comorbidities-in-adults-with-phenylketonuria-a-retrospective-cohort-study
#4
Deborah A Bilder, Joyce A Kobori, Jessica L Cohen-Pfeffer, Erin M Johnson, Elaina R Jurecki, Mitzie L Grant
Adults with phenylketonuria (PKU) may experience neurologic and psychiatric disorders, including intellectual disability, anxiety, depression, and neurocognitive dysfunction. Identifying the prevalence and prevalence ratios of these conditions will inform clinical treatment. This nested, case-controlled study used International Classification of Diseases, Ninth Revision (ICD-9) codes from the MarketScan® insurance claims databases from 2006 to 2012 and healthcare claims data for US-based employer and government-sponsored health plans...
March 6, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28270326/investigating-relationships-between-ptsd-symptom-clusters-within-virtual-reality-exposure-therapy-for-oef-oif-veterans
#5
Jessica L Maples-Keller, Matthew Price, Sheila Rauch, Maryrose Gerardi, Barbara O Rothbaum
Several cognitive behavioral therapeutic approaches have been demonstrated to be effective in reducing post-traumatic stress disorder (PTSD) symptoms (Foa, Keane, Friedman, & Cohen, 2008). The bulk of PTSD treatment research has relied on pre-post designs, which are limited in their ability to investigate the therapeutic process over time. The present study investigated the relations between PTSD symptom clusters using symptom assessment at pretreatment, midtreatment, and posttreatment using cross-lagged panel design over the course of Virtual Reality Exposure (VRE) treatment...
March 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28253315/introducing-malaria-rapid-diagnostic-tests-in-private-medicine-retail-outlets-a-systematic-literature-review
#6
Theodoor Visser, Katia Bruxvoort, Kathleen Maloney, Toby Leslie, Lawrence M Barat, Richard Allan, Evelyn K Ansah, Jennifer Anyanti, Ian Boulton, Siân E Clarke, Jessica L Cohen, Justin M Cohen, Andrea Cutherell, Caitlin Dolkart, Katie Eves, Günther Fink, Catherine Goodman, Eleanor Hutchinson, Sham Lal, Anthony Mbonye, Obinna Onwujekwe, Nora Petty, Julie Pontarollo, Stephen Poyer, David Schellenberg, Elizabeth Streat, Abigail Ward, Virginia Wiseman, Christopher J M Whitty, Shunmay Yeung, Jane Cunningham, Clare I R Chandler
BACKGROUND: Many patients with malaria-like symptoms seek treatment in private medicine retail outlets (PMR) that distribute malaria medicines but do not traditionally provide diagnostic services, potentially leading to overtreatment with antimalarial drugs. To achieve universal access to prompt parasite-based diagnosis, many malaria-endemic countries are considering scaling up malaria rapid diagnostic tests (RDTs) in these outlets, an intervention that may require legislative changes and major investments in supporting programs and infrastructures...
2017: PloS One
https://www.readbyqxmd.com/read/28236725/diagnostic-implications-of-review-of-systems-questionnaires-to-differentiate-epileptic-seizures-from-psychogenic-seizures
#7
Wesley T Kerr, Emily A Janio, Chelsea T Braesch, Justine M Le, Jessica M Hori, Akash B Patel, Sarah E Barritt, Norma L Gallardo, Janar Bauirjan, Andrea M Chau, Eric S Hwang, Emily C Davis, David Torres-Barba, Andrew Y Cho, Jerome Engel, Mark S Cohen, John M Stern
OBJECTIVE: Early and accurate diagnosis of patients with psychogenic nonepileptic seizures (PNES) leads to appropriate treatment and improves long-term seizure prognosis. However, this is complicated by the need to record seizures to make a definitive diagnosis. Suspicion for PNES can be raised through knowledge that patients with PNES have increased somatic sensitivity and report more positive complaints on review-of-systems questionnaires (RoSQs) than patients with epileptic seizures...
April 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28135187/the-association-of-marital-status-and-offers-of-employer-based-health-insurance-for-employed-women-aged-27-64-united-states-2014-2015
#8
Jessica L Simpson, Robin A Cohen
Data from the National Health Interview Survey •Among employed women aged 27-64, unmarried women (72.2%) were more likely than married women (69.3%) to have been offered health insurance by their employer. •Among employed married women aged 27-64, 16.8% were offered health insurance only through their spouse's employer. •Considering all offers of health insurance (through a woman's employer or her spouse's employer), employed married women aged 27-64 (86.1%) were more likely than employed unmarried women (72...
January 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/28089765/intracerebroventricular-delivery-as-a-safe-long-term-route-of-administration
#9
REVIEW
Jessica L Cohen-Pfeffer, Sridharan Gururangan, Thomas Lester, Daniel A Lim, Adam J Shaywitz, Manfred Westphal, Irene Slavc
Intrathecal delivery methods have been used for many decades to treat a broad range of central nervous system disorders. A literature review demonstrated that intracerebroventricular route is an established and well-tolerated method for prolonged central nervous system drug delivery in pediatric and adult populations. Intracerebroventricular devices were present in patients from one to 7156 days. The number of punctures per device ranged from 2 to 280. Noninfectious complication rates per patient (range, 1...
November 10, 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/28081302/education-and-support-needs-in-patients-with-head-and-neck-cancer-a-multi-institutional-survey
#10
Joe Jabbour, Chris Milross, Puma Sundaresan, Ardalan Ebrahimi, Heather L Shepherd, Haryana M Dhillon, Gary Morgan, Bruce Ashford, Muzib Abdul-Razak, Eva Wong, Michael Veness, Carsten E Palme, Cate Froggatt, Ruben Cohen, Rafael Ekmejian, Jessica Tay, David Roshan, Jonathan R Clark
BACKGROUND: Head and neck cancer (HNC) encompasses a diverse group of tumors, and thus providing appropriate and tailored information to patients before, during, and after treatment is a challenge. The objective of the current study was to characterize the experience and unmet needs of patients with HNC with regard to information and support provision. METHODS: A 28-question, cross-sectional survey was completed by patients treated for HNC at 1 of 4 institutions in New South Wales, Australia (Chris O'Brien Lifehouse and Liverpool, Westmead, and Wollongong hospitals)...
June 1, 2017: Cancer
https://www.readbyqxmd.com/read/28043901/mother-child-language-style-matching-predicts-children-s-and-mothers-emotion-reactivity
#11
Hannah F Rasmussen, Jessica L Borelli, Patricia A Smiley, Chloe Cohen, Ryan Cheuk Ming Cheung, Schuyler Fox, Matthew Marvin, Betsy Blackard
Co-regulation of behavior occurring within parent-child attachment relationships is thought to be the primary means through which children develop the capacity to regulate emotion, an ability that is protective across development. Existing research on parent-child co-regulation focuses predominantly on parent-infant dyads, and operationalizes co-regulation as the matching of facial expressions; however, matching can occur on other behaviors, including vocal tone, body movement, and language. Studies with young children find that greater matching is associated with children's lower emotion reactivity, but with unknown impacts on parents...
December 30, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27996898/the-legality-of-biometric-screening-of-professional-athletes
#12
Jessica L Roberts, I Glenn Cohen, Christopher R Deubert, Holly Fernandez Lynch
No abstract text is available yet for this article.
January 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/27974697/surrogate-in-vitro-activation-of-innate-immunity-synergizes-with-interleukin-7-to-unleash-rapid-antigen-driven-outgrowth-of-cd4-and-cd8-human-peripheral-blood-t-cells-naturally-recognizing-muc1-her2-neu-and-other-tumor-associated-antigens
#13
Latha B Pathangey, Dustin B McCurry, Sandra J Gendler, Ana L Dominguez, Jessica E Gorman, Girish Pathangey, Laurie A Mihalik, Yushe Dang, Mary L Disis, Peter A Cohen
Effective adoptive immunotherapy has proved elusive for many types of human cancer, often due to difficulties achieving robust expansion of natural tumor-specific T-cells from peripheral blood. We hypothesized that antigen-driven T-cell expansion might best be triggered in vitro by acute activation of innate immunity to mimic a life-threatening infection. Unfractionated peripheral blood mononuclear cells (PBMC) were subjected to a two-step culture, first synchronizing their exposure to exogenous antigens with aggressive surrogate activation of innate immunity, followed by γ-chain cytokine-modulated T-cell hyperexpansion...
February 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/27958883/glutaredoxin-1-deficiency-causes-fatty-liver-and-dyslipidemia-by-inhibiting-sirtuin-1
#14
Di Shao, Jingyan Han, Xiuyun Hou, Jessica Fry, Jessica B Behring, Francesca Seta, Michelle T Long, Hemant K Roy, Richard A Cohen, Reiko Matsui, Markus M Bachschmid
AIMS: Nonalcoholic fatty liver (NAFL) is a common liver disease associated with metabolic syndrome, obesity, and diabetes that is rising in prevalence worldwide. Various molecular perturbations of key regulators and enzymes in hepatic lipid metabolism cause NAFL. However, redox regulation through glutathione (GSH) adducts in NAFL remains largely elusive. Glutaredoxin-1 (Glrx) is a small thioltransferase that removes protein GSH adducts without having direct antioxidant properties. The liver contains abundant Glrx but its metabolic function is unknown...
February 16, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/27797661/a-case-series-on-the-effects-of-kripalu-yoga-for-generalized-anxiety-disorder
#15
Jessica R Morgan, Marlysa Sullivan, Akihiko Masuda, Erin Tully, Lindsey L Cohen, Page L Anderson
Generalized anxiety disorder (GAD) is a prevalent psychiatric disorder associated with substantial impairment and poor treatment response. Yoga influences processes that are linked to the maintenance of GAD including mindfulness, anxiety, and heart rate variability, but has yet to be evaluated among people with the disorder. The present study is a first step toward documenting the efficacy of yoga for reducing worry among people with GAD using a single-subject AB design case series and daily ratings of worry...
January 2016: International Journal of Yoga Therapy
https://www.readbyqxmd.com/read/27707828/fracture-in-the-elderly-multidisciplinary-rehabilitation-femur-a-phase-ii-randomised-feasibility-study-of-a-multidisciplinary-rehabilitation-package-following-hip-fracture
#16
Nefyn H Williams, Jessica L Roberts, Nafees Ud Din, Nicola Totton, Joanna M Charles, Claire A Hawkes, Val Morrison, Zoe Hoare, Michelle Williams, Aaron W Pritchard, Swapna Alexander, Andrew Lemmey, Robert T Woods, Catherine Sackley, Pip Logan, Rhiannon T Edwards, Clare Wilkinson
OBJECTIVE: To conduct a rigorous feasibility study for a future definitive parallel-group randomised controlled trial (RCT) and economic evaluation of an enhanced rehabilitation package for hip fracture. SETTING: Recruitment from 3 acute hospitals in North Wales. Intervention delivery in the community. PARTICIPANTS: Older adults (aged ≥65) who received surgical treatment for hip fracture, lived independently prior to fracture, had mental capacity (assessed by clinical team) and received rehabilitation in the North Wales area...
October 5, 2016: BMJ Open
https://www.readbyqxmd.com/read/27698471/anti-tubulin-drugs-conjugated-to-anti-erbb-antibodies-selectively-radiosensitize
#17
Stephen R Adams, Howard C Yang, Elamprakash N Savariar, Joe Aguilera, Jessica L Crisp, Karra A Jones, Michael A Whitney, Scott M Lippman, Ezra E W Cohen, Roger Y Tsien, Sunil J Advani
Tumour resistance to radiotherapy remains a barrier to improving cancer patient outcomes. To overcome radioresistance, certain drugs have been found to sensitize cells to ionizing radiation (IR). In theory, more potent radiosensitizing drugs should increase tumour kill and improve patient outcomes. In practice, clinical utility of potent radiosensitizing drugs is curtailed by off-target side effects. Here we report potent anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize to tumours based on surface receptor expression...
October 4, 2016: Nature Communications
https://www.readbyqxmd.com/read/27636116/genetic-and-environmental-associations-between-body-dissatisfaction-weight-preoccupation-and-binge-eating-evidence-for-a-common-factor-with-differential-loadings-across-symptom-type
#18
Shannon M O'Connor, Christopher R Beam, Xiaochen Luo, L Adelyn Cohen, Jessica L VanHuysse, Robert E Emery, Eric Turkheimer, Pamela K Keel, S Alexandra Burt, Michael Neale, Steven Boker, Kelly Klump
OBJECTIVE: Prior twin studies provide support for a single "common factor" that contributes genetic and environmental risk to a range of disordered eating symptoms. However, the common factor may be indexed less well by binge eating (BE) than other symptoms of eating disorders [i.e., body dissatisfaction (BD) and weight preoccupation (WP)]. We sought to explore the presence of a common factor and test whether loadings differed across three key symptoms (i.e., BE, BD, WP). METHOD: Disordered eating was assessed via self-report in 631 female twin pairs from the Michigan State University Twin Registry...
February 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/27604509/clinicians-experiences-with-the-fragile-x-clinical-and-research-consortium
#19
Jessica A Liu, Randi J Hagerman, Robert M Miller, Lisa T Craft, Brenda Finucane, Nicole Tartaglia, Elizabeth M Berry-Kravis, Stephanie L Sherman, Sharon A Kidd, Jeffrey Cohen
The objectives of the study were to assess the attitudes and experiences of clinicians involved in a consortium of clinics serving people with fragile X-associated disorders to gauge satisfaction with the consortium and its efforts to improve quality of life for patients and the community. An internet survey was sent to 26 fragile X (FX) clinic directors participating in the Fragile X Clinical and Research Consortium (FXCRC). Respondents were asked to complete 19 questions on consortium performance and outcomes relevant for their own clinic...
September 8, 2016: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/27521363/the-cervicovaginal-microbiota-and-its-associations-with-human-papillomavirus-detection-in-hiv-infected-and-hiv-uninfected-women
#20
Laura L Reimers, Supriya D Mehta, L Stewart Massad, Robert D Burk, Xianhong Xie, Jacques Ravel, Mardge H Cohen, Joel M Palefsky, Kathleen M Weber, Xiaonan Xue, Kathryn Anastos, Howard Minkoff, Jessica Atrio, Gypsyamber D'Souza, Qian Ye, Christine Colie, Christine P Zolnik, Gregory T Spear, Howard D Strickler
BACKGROUND:  Bacterial vaginosis (BV) is characterized by low abundance of Lactobacillus species, high pH, and immune cell infiltration and has been associated with an increased risk of human papillomavirus (HPV) infection. We molecularly assessed the cervicovaginal microbiota over time in human immunodeficiency virus (HIV)-infected and HIV-uninfected women to more comprehensively study the HPV-microbiota relationship, controlling for immune status. METHODS:  16S ribosomal RNA gene amplicon pyrosequencing and HPV DNA testing were conducted annually in serial cervicovaginal lavage specimens obtained over 8-10 years from African American women from Chicago, of whom 22 were HIV uninfected, 22 were HIV infected with a stable CD4(+) T-cell count of > 500 cells/mm(3), and 20 were HIV infected with progressive immunosuppression...
November 1, 2016: Journal of Infectious Diseases
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