keyword
https://read.qxmd.com/read/38525841/rapid-formation-of-aortoesophageal-fistula-complicated-by-mycotic-thoracic-aortic-aneurysm-secondary-to-infective-endocarditis
#1
JOURNAL ARTICLE
Maki Setake, Yasuhiro Uechi, Yuzuru Kinjo, Masaru Miyazato, Noriya Nakachi, Ryosaku Tomiyama, Namio Higa, Akira Hokama
A 73-year-old man was admitted with four weeks of intermittent fever. He had a history of total aortic arch replacement for aortic arch aneurysm four years prior. CT scans showed no abnormalities before admission. Repeated blood cultures yielded Streptococcus anginosus and Prevotella melaninogenica, suggesting infective endocarditis (IE). Transesophageal echocardiography revealed a vegetation on the aortic valve, confirming IE. He suddenly presented with massive hematemesis and hypotension. Endoscopy revealed an elevated lesion with a laceration but no active bleeding in the esophagus...
March 25, 2024: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/38523954/management-of-acute-saddle-pulmonary-embolism-in-pregnancy-following-fetal-surgery
#2
Patrick J Connell, Leonardo A Marquez Roa, Jorge Araujo-Duran, Monica Cheriyan, Sabry Ayad
A 33-year-old gravidity three parity three (G3P3) woman at 34 weeks of pregnancy underwent fetal surgery to repair an open lumbosacral myelomeningocele at 22 weeks gestation and experienced preterm premature rupture of membranes as a result. She developed a saddle pulmonary embolus with signs of right heart strain while on prolonged bed rest. She was treated emergently with aspiration thrombectomy and suprarenal inferior vena cava (IVC) filter placement, followed by an uncomplicated cesarean delivery thereafter...
February 2024: Curēus
https://read.qxmd.com/read/38520890/massive-intracerebral-hemorrhage-following-methamphetamine-poisoning-in-a-man-a-case-report
#3
Elham Sadat Banimostafavi, Amirmasoud Taheri, Abdollah Malakian, Zakaria Zakariaei
INTRODUCTION AND IMPORTANCE: Methamphetamine (MAP) is a highly addictive stimulant known to have detrimental effects on the brain and various physiological systems, including an elevation in heart rate and blood pressure. Additionally, MAP use has been linked to the development of intracerebral hemorrhage (ICH), a serious and potentially fatal condition that is notably prevalent among young individuals. CASE PRESENTATION: We present the case of a 42-year-old man who suffered a massive ICH due to hypertension resulting from MAP poisoning...
March 14, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38518467/two-cases-of-dieulafoy-s-lesion-in-unusual-sites-a-rare-case-reports-of-gastrointestinal-bleeding
#4
Abdelkrim Zazour, Chifaa Belkhayat, Amal Bennani, Mohamed Bouziane, Ghizlane Kharrasse, Zahi Ismaili
INTRODUCTION: Dieulafoy's lesion (DL) is a vascular malformation that can lead to massive gastrointestinal bleeding. It's usually found in the stomach. However, DL's occurrence in atypical sites such as the small bowel and colon is exceptionally rare, posing significant management challenges. CASE PRESENTATION: In this report, we present two cases of DL occurring in uncommon sites, each managed with distinct approaches. Case 1 is a 50-year-old man admitted to the emergency department due to massive GI bleeding and hemodynamic instability...
March 19, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38514067/a-rare-autopsy-case-of-aggressive-combined-hepatocellular-cholangiocarcinoma-in-59-year-old-female
#5
JOURNAL ARTICLE
Ahmed A Ahmed, Brandon Gehris, Michelle McDonald, Suhair Al Salihi, L Maximilian Buja
Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a liver tumor with features of both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). It consists of intermingled malignant biliary and hepatic tissue and thus a distinct entity, rather than two separate coexisting malignancies. A 59-year-old female with a history of hepatitis C and cirrhosis presented with abdominal pain and altered mental status. She developed hematemesis, and despite extensive interventions, she expired one day after her initial presentation...
January 2024: Annals of Clinical and Laboratory Science
https://read.qxmd.com/read/38511721/increased-platelet-to-red-blood-cell-transfusion-ratio-associated-with-acute-kidney-injury-in-children-with-life-threatening-bleeding
#6
JOURNAL ARTICLE
Rachel Vaizer, Christine M Leeper, Liling Lu, Cassandra D Josephson, Julie C Leonard, Joshua B Brown, Philip C Spinella
INTRODUCTION: Transfusion may increase the risk of organ failure through immunomodulatory effects. The primary objective of this study was to assess for patient or transfusion-related factors that are independently associated with the risk of acute kidney injury (AKI) and acute respiratory distress syndrome (ARDS) in a cohort of children with life-threatening bleeding from all etiologies. METHODS: In a secondary analysis of the prospective observational massive transfusion in children (MATIC) study, multivariable logistic regression was performed in an adjusted analysis to determine if blood product ratios or deficits were independently associated with AKI or ARDS in children with life-threatening bleeding...
March 21, 2024: Transfusion
https://read.qxmd.com/read/38505594/anesthetic-managements-morbidities-and-mortalities-in-retroperitoneal-sarcoma-patients-experiencing-perioperative-massive-blood-transfusion
#7
JOURNAL ARTICLE
Jun Wang, Jun Chen, Kunpeng Liu, Hua Zhang, Yue Wei, Libin Suo, Shuang Lan, Yanzhen Wang, Chenghua Luo, Lan Yao
OBJECTIVE: Given high risks of major bleeding during retroperitoneal sarcoma(RPS) surgeries, severe complications and deaths are common to see perioperatively. Thus, effective anesthetic management is the key point to ensuring the safety of patients. This study aimed to introduce anesthesia management and mortalities in RPS patients receiving massive blood transfusions during surgeries. METHODS: Records of RPS surgeries under general anesthesia from January 2016 through December 2021 were retrospectively retrieved from our database...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38501231/survey-of-policies-at-us-hospitals-on-the-selection-of-rhd-type-of-low-titer-o-whole-blood-for-use-in-trauma-resuscitation
#8
JOURNAL ARTICLE
Skye Clayton, Christine M Leeper, Mark H Yazer, Philip C Spinella
BACKGROUND: Low-titer group O whole blood (LTOWB) use is increasing due to data suggesting improved outcomes and safety. One barrier to use is low availability of RhD-negative LTOWB. This survey examined US hospital policies regarding the selection of RhD type of blood products in bleeding emergencies. STUDY DESIGN AND METHODS: A web-based survey of blood bank directors was conducted to determine their hospital's RhD-type selection policies for blood issued for massive bleeding...
March 19, 2024: Transfusion
https://read.qxmd.com/read/38500639/elective-surgery-for-liver-injury-and-misinserted-tube-into-the-inferior-vena-cava-associated-with-chest-tube-replacement-a-case-report
#9
Hiroshi Homma, Kenichiro Uchibori, Fumimasa Kobori, Kentaro Kawai, Kazunari Azuma, Shoji Suzuki, Kotaro Uchida, Jun Oda
BACKGROUND: Several reports on organ injury and death due to incorrect chest tube insertion exist; however, reports on the chest tube penetrating the liver and reaching the inferior vena cava are limited. CASE PRESENTATION: A 79-year-old man presented with a clamped tube because of massive bleeding from the tube following right chest tube replacement in the hospital of origin. The tube entered the inferior vena cava from the hepatic parenchyma via the right hepatic vein and was removed 15 h later because his hemodynamics stabilized...
2024: Acute Medicine & Surgery
https://read.qxmd.com/read/38497862/preoperative-bmi-and-hb-levels-are-important-predictors-of-massive-bleeding-in-liver-transplant-patients
#10
JOURNAL ARTICLE
K-D Chen, W Chen, B Hu, Z-S Zhao
OBJECTIVE: This study aims to compare intraoperative bleeding during liver transplant procedures and analyze the predictive role of preoperative laboratory indicators in significant intraoperative bleeding. PATIENTS AND METHODS: A retrospective analysis was conducted on 271 cases of allogeneic liver transplant patients from January 2018 to June 2023. Patients were categorized into the massive bleeding (MB) group and the non-massive bleeding (non-MB) group based on the occurrence of significant intraoperative bleeding...
March 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38496787/uterine-vascular-abnormalities-linked-to-pregnancy-complications-color-and-power-doppler-assisted-transvaginal-ultrasound-evaluation
#11
JOURNAL ARTICLE
Ashraf Talaat Youssef
AIM: Abnormal uterine vascular pattern can be observed during transvaginal ultrasound examination used for investigating post-abortion bleeding and secondary postpartum hemorrhage. The purpose of this series of cases was to evaluate almost all the rare causes of uterine vascular abnormalities linked to pregnancy complications, and determine how to arrive at the diagnosis to optimize patient management, which is crucial for preventing life-threatening massive vaginal bleeding. MATERIAL AND METHODS: Retrospective observational case series study including 20 women with postpartum or post-abortion vaginal bleeding who were found to have an abnormal uterine vascular pattern during a transvaginal color duplex assessment...
February 2024: Journal of Ultrasonography
https://read.qxmd.com/read/38495915/what-else-should-hemostatic-materials-do-beyond-hemostasis-a-review
#12
REVIEW
Xinran Yang, Xiudan Wang, Xing Gao, Xiaoqin Guo, Shike Hou, Jie Shi, Qi Lv
Massive blood loss due to injury is the leading cause of prehospital deaths in disasters and emergencies. Hemostatic materials are used to realize rapid hemostasis and protect patients from death. Researchers have designed and developed a variety of hemostatic materials. However, in addition to their hemostatic effect, hemostatic materials must be endowed with additional functions to meet the practical application requirements in different scenarios. Here, strategies for modifications of hemostatic materials for use in different application scenarios are listed: effective positioning at the site of deep and narrow wounds to stop bleeding, resistance to high blood pressure and wound movement to maintain wound formation, rapid and easy removal from the wound without affecting further treatment after hemostasis is completed, and continued function when retained in the wound as a dressing (such as antibacterial, antiadhesion, tissue repair, etc...
April 2024: Materials today. Bio
https://read.qxmd.com/read/38494729/an-autopsy-case-of-fulminant-myocarditis-with-massive-left-ventricular-calcification
#13
JOURNAL ARTICLE
Satsuki Yagi-Nakajima, Masanobu Miura, Shun Sawada, Takahiro Funaki, Kumi Uchimura, Kai Susukita, Tsubasa Hatakeyama, Yuta Kagaya, Hiroki Saito, Kenjiro Sato, Masanori Kanazawa, Masateru Kondo, Hideaki Endo, Hiroshi Yaegashi, Akihiro Nakamura
Myocardial calcification in myocarditis is rare and may be linked to poor outcomes. We herein report a case of fulminant myocarditis with massive myocardial calcification and its pathological outcomes at autopsy. A 49-year-old man experienced chest pain and was diagnosed with acute myocarditis. His cardiac function did not recover despite mechanical circulatory support in combination with V-A extracorporeal membrane oxygenation and IMPELLA CP® . He eventually developed sepsis and gastrointestinal bleeding and died on day 27...
2024: Internal Medicine
https://read.qxmd.com/read/38493157/the-localization-origin-and-impact-of-platelets-in-the-tumor-microenvironment-are-tumor-type-dependent
#14
JOURNAL ARTICLE
Ophélie Le Chapelain, Soumaya Jadoui, Angèle Gros, Samir Barbaria, Keltouma Benmeziane, Véronique Ollivier, Sébastien Dupont, Mialitiana Solo Nomenjanahary, Sabrina Mavouna, Jasmina Rogozarski, Marie-Anne Mawhin, Giuseppina Caligiuri, Sandrine Delbosc, Françoise Porteu, Bernhard Nieswandt, Pierre H Mangin, Yacine Boulaftali, Benoit Ho-Tin-Noé
BACKGROUND: How platelets interact with and influence the tumor microenvironment (TME) remains poorly characterized. METHODS: We compared the presence and participation of platelets in the TME of two tumors characterized by highly different TME, PyMT AT-3 mammary tumors and B16F1 melanoma. RESULTS: We show that whereas firmly adherent platelets continuously line tumor vessels of both AT-3 and B16F1 tumors, abundant extravascular stromal clusters of platelets from thrombopoietin-independent origin were present only in AT-3 mammary tumors...
March 16, 2024: Journal of Experimental & Clinical Cancer Research: CR
https://read.qxmd.com/read/38490704/congenital-brain-tumour-in-a-neonate-a-therapeutic-challenge
#15
JOURNAL ARTICLE
Praneetha Mude, Monalisa Pradhan, Anuj Tiwari, Tapas Kanti Parida, Manoj Kumar Nayak, Arun Kumar Sekar, Suvendu Purkait, Usha Devi
A term neonate with history of ventriculomegaly in the fetal period was diagnosed with a central nervous system tumour after radiological investigations. It was confirmed as an immature teratoma after histopathological examination. He underwent left frontal craniotomy with tumour excision. Intraoperatively, massive haemorrhage (venous bleed) occurred due to the high vascularity of the tumour and led to haemodynamic instability. A massive transfusion protocol was initiated. Despite multiple transfusions and shock management, he succumbed at 2 weeks of life...
March 15, 2024: BMJ Case Reports
https://read.qxmd.com/read/38483820/tranexamic-acid-safeguarding-children-with-craniosynostosis-from-bleeding-a-review-article
#16
REVIEW
Khildan Miftahul Firdaus, Lucky Andriyanto, Adil Jihad Muhammad, Tatang Bisri
Craniosynostosis is a congenital condition characterized by the premature closure of one or more sutures in the skull after birth, often necessitating urgent surgical intervention. Nevertheless, cranial vault reconstruction surgery can cause rapid and massive blood loss. This procedure requires a blood transfusion, which entails potential hazards. In addition, the hemostatic system in children differs significantly from that in adults, resulting in increased bleeding during surgical procedures. We conducted a comprehensive literature review in the PubMed, Scopus, and Web of Science databases, referring to their inception for studies on the use of tranexamic acid in pediatric craniosynostosis surgery...
March 14, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38479844/post-renal-acute-kidney-injury-complicated-by-urinary-tract-obstruction-due-to-massive-blood-clots-and-severe-thrombocytopenia-in-a-patient-with-systemic-lupus-erythematosus-a-case-report
#17
JOURNAL ARTICLE
Yuya Fujita, Shuzo Sato, Shuhei Yoshida, Tomoyuki Asano, Haruki Matsumoto, Jumpei Temmoku, Naoki Matsuoka, Hiroshi Ohkawara, Norshalena Shakespear, Kiyoshi Migita
Systemic lupus erythematosus (SLE) is often seen with antiphospholipid antibody syndrome (APS), and these conditions may occur concurrently with severe immune thrombocytopenia and even acute kidney injury (AKI); however, post-renal AKI due to bleeding is uncommon. Here, we describe a case of post-renal AKI and anuria in a patient with SLE and APS, which were attributable to urinary tract obstruction due to massive blood clots caused by secondary immune thrombocytopenia. A 50-year-old Japanese woman was admitted to our hospital with anuria, abdominal tenderness, purpura in the trunk and in both legs, and severe thrombocytopenia...
March 14, 2024: Modern rheumatology case reports
https://read.qxmd.com/read/38479825/case-of-giant-juvenile-angiofibroma-resected-by-external-incision-with-temporary-double-balloon-occlusion-of-the-internal-carotid-artery-by-intraoperative-endovascular-treatment
#18
JOURNAL ARTICLE
Mayuka Maeda-Anezaki, Kazuhiro Omura, Ryosuke Mori, Katsuhiro Ishida
We report the first case of a juvenile nasal angiofibroma (JNA) fed by multiple arteries from the internal carotid artery (ICA), removed without complications by temporarily blocking the ICA with two balloons. An early adolescent with JNA underwent preoperative embolisation of feeding arteries arising from the external carotid artery (ECA) (University of Pittsburgh Medical Centre classification IV). Endoscopic resection was attempted once but discontinued due to massive bleeding (7000 mL). 17 months later, the JNA had grown to fill both nasal cavities...
March 13, 2024: BMJ Case Reports
https://read.qxmd.com/read/38477567/carbonized-cellulose-aerogel-derived-from-waste-pomelo-peel-for-rapid-hemostasis-of-trauma-induced-bleeding
#19
JOURNAL ARTICLE
Wenbing Wan, Yang Feng, Jiang Tan, Huiping Zeng, Rafeek Khan Jalaludeen, Xiaoxi Zeng, Bin Zheng, Jingchun Song, Xiyue Zhang, Shixuan Chen, Jingye Pan
Uncontrollable massive bleeding caused by trauma will cause the patient to lose a large amount of blood and drop body temperature quickly, resulting in hemorrhagic shock. This study aims to develop a hemostatic product for hemorrhage management. In this study, waste pomelo peel as raw material is chosen. It underwent processes of carbonization, purification, and freeze-drying. The obtained carbonized pomelo peel (CPP) is hydrophilic and exhibits a porous structure (nearly 80% porosity). The water/blood absorption ratio is significantly faster than the commercial Gelfoam and has a similar water/blood absorption capacity...
March 13, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38469798/massive-esophageal-perforation-managed-with-a-covered-esophageal-stent
#20
JOURNAL ARTICLE
Jonathan Acosta-Contento, Carlos Ortiz-Moyano, Alma Keco-Huerga
Esophageal stents have become an emergent, effective treatment for esophageal perforation, whether spontaneous or iatrogenic. We report a case of iatrogenic perforation secondary to malposition of a Sengstaken-Blakemore balloon (SBB), which was inserted to control acute variceal bleeding. SBB currently has very limited indications in the management of variceal bleeding given the ongoing advances in endoscopic techniques, and its use is not exempt from complications such as the one reported herein.
March 12, 2024: Revista Española de Enfermedades Digestivas
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