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Transient tachypnea of newborn

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https://www.readbyqxmd.com/read/27843177/structural-cardiac-lesions-in-transient-tachypnea-of-the-newborn
#1
Shankar Narayan, R Ananthakrishnan, Gurpreet Kaur
BACKGROUND: Transient tachypnea of the newborn (TTN) is considered a benign disorder. Given its self-limiting nature, few studies have looked for associated pathology. This study explores the association of TTN with structural cardiac lesions. METHODS: Over a six-month period, all inborn term and late preterm neonates with TTN (without predisposing factors) underwent 2D echocardiography within the first ten days of life, after tachypnea had subsided. Equal number of neonates born during the same period, matched for birth weight, gestational age, sex, and mode of delivery but without tachypnea, also underwent echocardiography before ten days of life...
October 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/27733360/antenatal-corticosteroids-for-maturity-of-term-or-near-term-fetuses-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#2
Gabriele Saccone, Vincenzo Berghella
OBJECTIVE:  To evaluate the effectiveness of antenatal corticosteroids given at ≥34 weeks' gestation. DESIGN:  Systematic review with meta-analysis. DATA SOURCES:  Electronic databases were searched from their inception to February 2016. ELIGIBILITY CRITERIA FOR STUDY SELECTION:  Randomized clinical trials comparing antenatal corticosteroids with placebo or no treatment in women with a singleton pregnancy at ≥34 weeks' gestation...
October 12, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27717357/perfusion-index-assessment-during-transition-period-of-newborns-an-observational-study
#3
Sezin Unal, Ebru Ergenekon, Selma Aktas, Serdar Beken, Nilgun Altuntas, Ebru Kazanci, Ferit Kulali, Ibrahim M Hirfanoglu, Esra Onal, Canan Turkyilmaz, Esin Koc, Yildiz Atalay
BACKGROUND: Perfusion index (PI) is becoming a part of clinical practice in neonatology to monitor peripheral perfusion noninvasively. Hemodynamic and respiratory changes occur in newborns during the transition period after birth in which peripheral perfusion may be affected. Tachypnea is a frequent symptom during this period. While some tachypneic newborns get well in less than 6 h and diagnosed as "delayed transition", others get admitted to intensive care unit which transient tachypnea of newborn (TTN) being the most common diagnosis among them...
October 7, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27659026/hypothyroxinemia-and-risk-for-transient-tachypnea-of-newborn
#4
Irena Ulanovsky, Tatiana Smolkin, Shlomo Almashanu, Tanya Mashiach, Imad R Makhoul
Transient tachypnea of newborn is associated with hypothyroxinemia in animals via decreased stimulation of beta-adrenergic receptors and Na-K-ATPase activity. In 26 549 term neonates, serum total thyroxine <14 ug/dL, male sex, and elective cesarean delivery were significantly associated with greater risk for transient tachypnea of newborn.
September 19, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27650628/pregnancy-outcome-after-false-diagnosis-of-fetal-growth-restriction
#5
Rinat Gabbay-Benziv, Amir Aviram, Eran Hadar, Rony Chen, Ron Bardin, Arnon Wiznitzer, Yariv Yogev
OBJECTIVES: To evaluate pregnancy outcome following false diagnosis of fetal growth restriction (FGR). METHODS: Retrospective analysis of all singleton term deliveries of appropriately grown fetuses (10-90th weight percentiles) in a single medical center (2007-2014). Elective cesarean-section, diabetes, and hypertension were excluded. Cohort was stratified based on third trimester sonographic estimated-fetal-weight (≥32 weeks). Women with false diagnosis FGR (<10th percentile) were compared with the rest (control)...
September 21, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27642489/neonatal-respiratory-distress-in-a-reference-neonatal-unit-in-cameroon-an-analysis-of-prevalence-predictors-etiologies-and-outcomes
#6
Joel Noutakdie Tochie, Simeon-Pierre Choukem, Regina Ndasi Langmia, Esther Barla, Paul Koki-Ndombo
INTRODUCTION: Neonatal respiratory distress (NRD) is a main cause of neonatal morbidity and mortality in developing countries. Early detection of its risk factors and early treatment of its etiologies are major challenges. However, few studies in developing countries have provided data needed to tackle it. We aimed to determine the prevalence, predictors, etiologies and outcome of NRD in a tertiary health care centre of Cameroon. METHODS: We analyzed the hospital files of all newborns admitted to the Neonatal unit of Douala General Hospital from 1(st) January 2011 to 28(th) February 2013...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27607482/persistent-grunting-respirations-after-birth
#7
Gustavo M Rocha, Filipa S Flor-DE-Lima, Hercília A Guimaraes
BACKGROUND: Grunting respirations occurring in the first hours of life is a frequent nonspecific clinical sign. Our objective was to assess the clinical significance of grunting lasting over two hours of birth in term and near term newborns. +0 METHODS: A five years retrospective study of all newborns >35 weeks of gestational age admitted for grunting to a level III NICU. RESULTS: Prolongued grunting occurred in 1.2% of the delivered newborns. Data on 151 grunter newborns and 302 controls were reviewed...
September 8, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27464019/maternal-super-obesity-and-neonatal-morbidity-after-term-cesarean-delivery
#8
Marcela C Smid, Catherine J Vladutiu, Sarah K Dotters-Katz, Tracy A Manuck, Kim A Boggess, David M Stamilio
Objective To estimate the association between maternal super obesity (body mass index [BMI] ≥ 50 kg/m(2)) and neonatal morbidity among neonates born via cesarean delivery (CD). Methods Retrospective cohort of singleton neonates delivered via CD ≥ 37 weeks in the Maternal-Fetal Medicine Unit Cesarean Registry. Maternal BMI at delivery was stratified as 18.5 to 29.9 kg/m(2), 30 to 39.9 kg/m(2), 40 to 49.9 kg/m(2), and ≥ 50 kg/m(2). Primary outcomes included acute (5-minute Apgar score < 5, cardiopulmonary resuscitation and ventilator support < 24 hours, neonatal injury, and/or transient tachypnea of the newborn) and severe (grade 3 or 4 intraventricular hemorrhage, necrotizing enterocolitis, seizure, respiratory distress syndrome, hypoxic ischemic encephalopathy, meconium aspiration, ventilator support ≥ 2 days, sepsis and/or neonatal death) neonatal morbidity...
October 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27342043/antenatal-corticosteroids-beyond-34-weeks-gestation-what%C3%A2-do%C3%A2-we%C3%A2-do%C3%A2-now
#9
REVIEW
Beena D Kamath-Rayne, Paul J Rozance, Robert L Goldenberg, Alan H Jobe
The practice of antenatal corticosteroid administration in pregnancies of 24-34 weeks of gestation that are at risk of preterm delivery was adopted over 20 years after the first randomized clinical trial in humans. It is biologically plausible that antenatal corticosteroid in pregnancies beyond 34 weeks of gestation would reduce rates of respiratory morbidity and neonatal intensive care admission. Mostly guided by the results of a large multicenter randomized trial of antenatal corticosteroid in late preterm infants, the Antenatal Late Preterm Steroids Trial, the American Congress of Obstetricians and Gynecologists has released a practice advisory that the "administration of betamethasone may be considered in women with a singleton pregnancy between 34 0/7 and 36 6/7 weeks of gestation at imminent risk of preterm birth within 7 days...
October 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27336017/the-effects-of-inhaled-%C3%AE-adrenergic-agonists-in-transient-tachypnea-of-the-newborn
#10
Esengul Keleş, Arzu Gebeşçe, Mehmet Demirdöven, Hamza Yazgan, Bülent Baştürk, Alparslan Tonbul
Aim. To investigate the efficacy of an inhaled β-adrenergic agonists in transient tachypnea of the newborn (TTN). Method. We retrospectively analyzed a cohort of 51 term infants (Group 1) and 37 term infants (Group 2) monitored in the newborn intensive care unit diagnosed with TTN. Infants in Group 1 received humidified oxygen alone, and infants in Group 2 were administered the inhaled β-2 agonist plus humidified oxygen. Results. TTN clinical respiratory assessment, respiratory rate, oxygen saturation values, need for supplemental oxygen therapy, blood gas PH, PO2, and duration of hospitalization were significantly improved in infants in Group 2 as compared with infants in Group 1 (P < ...
2016: Global Pediatric Health
https://www.readbyqxmd.com/read/27225963/the-fetal-circulation-pathophysiology-of-hypoxemic-respiratory-failure-and-pulmonary-hypertension-in-neonates-and-the-role-of-oxygen-therapy
#11
REVIEW
S Lakshminrusimha, O D Saugstad
Neonatal hypoxemic respiratory failure (HRF), a deficiency of oxygenation associated with insufficient ventilation, can occur due to a variety of etiologies. HRF can result when pulmonary vascular resistance (PVR) fails to decrease at birth, leading to persistent pulmonary hypertension of newborn (PPHN), or as a result of various lung disorders including congenital abnormalities such as diaphragmatic hernia, and disorders of transition such as respiratory distress syndrome, transient tachypnea of newborn and perinatal asphyxia...
June 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27225520/obstetric-outcomes-of-isolated-oligohydramnios-during-early-term-full-term-and-late-term-periods-and-determination-of-optimal-timing-of-delivery
#12
Ertugrul Karahanoglu, Funda Akpinar, Erhan Demirdag, Neslihan Yerebasmaz, Tugba Ensari, Aysegul Akyol, Dilek Ulubas Isik, Serdar Yalvac
AIM: Our aim was to evaluate the obstetric outcomes of isolated oligohydramnios during the early-term, full-term, and late-term periods, and to determine the optimal timing of delivery. METHODS: A retrospective study was performed at a tertiary center. Isolated oligohydramnios cases were divided into early-term, full-term, and late-term groups. Evaluated outcomes were fetal birthweight, 5-min Apgar score < 7, meconium-stained amniotic fluid, neonatal intensive care unit admission, transient tachypnea of newborn (TTN), requirement of ventilator, newborn jaundice, mode of delivery, induction of labor, and undiagnosed small-for-gestational-age fetus before delivery...
September 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27220313/lung-ultrasound-as-a-predictor-of-mechanical-ventilation-in-neonates-older-than-32-weeks
#13
Javier Rodríguez-Fanjul, Carla Balcells, Victoria Aldecoa-Bilbao, Julio Moreno, Martín Iriondo
BACKGROUND: The prognosis of neonatal respiratory distress may be difficult to estimate at admission. Lung ultrasound is a useful diagnostic tool that is quick, requires little training, and is radiation free. OBJECTIVE: This study aims to analyze whether early lung ultrasound can predict respiratory failure. METHODS: From January to December 2014, lung ultrasound was performed on neonates admitted with breathing difficulties if they were older than 32 weeks and not intubated...
2016: Neonatology
https://www.readbyqxmd.com/read/27211231/epinephrine-for-transient-tachypnea-of-the-newborn
#14
REVIEW
Luca Moresco, Maria Grazia Calevo, Federica Baldi, Amnon Cohen, Matteo Bruschettini
BACKGROUND: Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress. Transient tachypnea typically appears within the first two hours of life in term and late preterm newborns. Although transient tachypnea of the newborn is usually a self limited condition, it is associated with wheezing syndromes in late childhood. The rationale for the use of epinephrine (adrenaline) for transient tachypnea of the newborn is based on studies showing that β-agonists can accelerate the rate of alveolar fluid clearance...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27210618/salbutamol-for-transient-tachypnea-of-the-newborn
#15
REVIEW
Luca Moresco, Matteo Bruschettini, Amnon Cohen, Alberto Gaiero, Maria Grazia Calevo
BACKGROUND: Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress. Transient tachypnea typically appears within the first two hours of life in term and late preterm newborns. Although transient tachypnea of the newborn is usually a self limited condition, it is associated with wheezing syndromes in late childhood. The rationale for the use of salbutamol (albuterol) for transient tachypnea of the newborn is based on studies showing that β-agonists can accelerate the rate of alveolar fluid clearance...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27089397/respiratory-morbidity-in-twins-by-birth-order-gestational-age-and-mode-of-delivery
#16
Katja Bricelj, Natasa Tul, Mateja Lasic, Andreja Trojner Bregar, Ivan Verdenik, Miha Lucovnik, Isaac Blickstein
OBJECTIVE: To evaluate the relationship between respiratory morbidity in twins by gestational age, birth order and mode of delivery. METHODS: All twin deliveries at <37 weeks, registered in a national database, in the period 2003-2012 were classified into four gestational age groups: 33-36, 30-32, 28-29, and <28 weeks. Outcome variables included transient tachypnea of the newborn (TTN), respiratory distress syndrome (RDS) and need for assisted ventilation...
April 18, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27077685/respiratory-morbidity-in-late-preterm-infants
#17
Claudia Correia, Gustavo Rocha, Filipa Flor-DE-Lima, Hercília Guimarães
BACKGROUND: Late preterm delivery (74% of all preterm births) increases the incidence of respiratory pathology, namely respiratory distress syndrome (RDS), transient tachypnea of the newborn (TTN) and the need of ventilator support when compared to term delivery. The aim is to evaluate the respiratory morbimortality in late preterm infants and the risk factors associated with RDS and TTN. METHODS: Descriptive retrospective study of all newborns of 34+0 to 36+6 weeks of gestational age, born at our centre between September 1, 2012 and August 31, 2015...
April 14, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27057773/timing-of-medically-indicated-delivery-in-diabetic-pregnancies-a-perspective-on-current-evidence-based-recommendations
#18
Oscar A Viteri, Jenifer Dinis, Tania Roman, Baha M Sibai
Diabetes complicates 6 to 7% of all pregnancies in the United States. Poor glycemic control is associated with multiple immediate and long-term adverse effects on both the mother and fetus. Although uniformity exists in the antenatal management of this disease, there is a paucity of evidence-based studies upon which to dictate the optimal time of delivery among affected women. The potential risks of delayed neonatal pulmonary maturation including respiratory distress syndrome and transient tachypnea of the newborn associated with early delivery must be balanced with the increased incidence of fetal demise, overgrowth, and birth injury related to diabetes in late gestations...
July 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27052752/neonatal-respiratory-morbidity-in-late-preterm-births-in-pregnancies-with-and-without-gestational-diabetes-mellitus
#19
Katja Bricelj, Natasa Tul, Miha Lucovnik, Lilijana Kronhauser-Cerar, Lili Steblovnik, Ivan Verdenik, Isaac Blickstein
OBJECTIVE: To evaluate neonatal respiratory morbidity in infants born late-preterm to mothers with or without gestational diabetes mellitus (GDM). METHODS: Analysis of a population-based cohort of all live-born singletons, born at 34 0/7 to 36 6/7 weeks to mothers with and without GDM, focusing on transient tachypnea of the newborn (TTN) and respiratory distress syndrome (RDS). RESULTS: The study group comprised 363 (4.7%) singletons born to mothers with GDM and the controls were 7400 born to mothers without GDM...
April 7, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27002271/antenatal-corticosteroids-in-the-late-preterm-period-a-prospective-cohort-study
#20
M K Ramadan, G Hussein, W Saheb, M Rajab, F G Mirza
OBJECTIVE: The study objective was to examine the effect of antenatal corticosteroids on the incidence of short-term neonatal morbidities in singletons born during the late preterm period. STUDY DESIGN: This was a prospective cohort study of singleton gestations at risk of imminent delivery between 34 0/7 and 36 6/7 weeks. Short-term neonatal morbidities were compared between the corticosteroid exposed and non-exposed groups. The rates of Neonatal Morbidity Composite and Any Adverse Neonatal Morbidity were then compared between the two groups...
2016: Journal of Neonatal-perinatal Medicine
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