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https://www.readbyqxmd.com/read/28522948/evaluation-of-xpert-mtb-rif-assay-performance-in-the-diagnosis-of-abdominal-tuberculosis
#1
Suraj Kumar, Sawan Bopanna, Saurabh Kedia, Pratap Mouli, Rajan Dhingra, Rajesh Padhan, Mikashmi Kohli, Jigyasa Chaubey, Rohini Sharma, Prasenjit Das, S Dattagupta, Govind Makharia, S K Sharma, Vineet Ahuja
BACKGROUND/AIMS: The use of genetic probes for the diagnosis of pulmonary tuberculosis (TB) has been well described. However, the role of these assays in the diagnosis of intestinal tuberculosis is unclear. We therefore assessed the diagnostic utility of the Xpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) assay, and estimated the prevalence of multidrug-resistant (MDR) TB in the Indian population. METHODS: Of 99 patients recruited, 37 had intestinal TB; two control groups comprised 43 with Crohn's disease (CD) and 19 with irritable bowel syndrome...
April 2017: Intestinal Research
https://www.readbyqxmd.com/read/28522943/accuracy-of-computed-tomographic-features-in-differentiating-intestinal-tuberculosis-from-crohn-s-disease-a-systematic-review-with-meta-analysis
#2
REVIEW
Saurabh Kedia, Raju Sharma, Vishnubhatla Sreenivas, Kumble Seetharama Madhusudhan, Vishal Sharma, Sawan Bopanna, Venigalla Pratap Mouli, Rajan Dhingra, Dawesh Prakash Yadav, Govind Makharia, Vineet Ahuja
Abdominal computed tomography (CT) can noninvasively image the entire gastrointestinal tract and assess extraintestinal features that are important in differentiating Crohn's disease (CD) and intestinal tuberculosis (ITB). The present meta-analysis pooled the results of all studies on the role of CT abdomen in differentiating between CD and ITB. We searched PubMed and Embase for all publications in English that analyzed the features differentiating between CD and ITB on abdominal CT. The features included comb sign, necrotic lymph nodes, asymmetric bowel wall thickening, skip lesions, fibrofatty proliferation, mural stratification, ileocaecal area, long segment, and left colonic involvements...
April 2017: Intestinal Research
https://www.readbyqxmd.com/read/28521786/role-of-routine-abdominal-ultrasonography-in-intensified-tuberculosis-case-finding-algorithms-at-hiv-clinics-in-high-tb-burden-settings
#3
Sonam Spalgais, Upasna Agarwal, Rohit Sarin, Devesh Chauhan, Anita Yadav, Anand Jaiswal
BACKGROUND: High proportion of TB in people living with HIV (PLHIV) is undiagnosed. Due to this active TB case finding is recommended for HIV clinics in high TB burden countries. Presently sputum examination and chest radiography are frontline tests recommended for HIV infected TB presumptives. Abdominal TB which occurs frequently in PLHIV may be missed even by existing programmatic intensified case finding protocols. This study evaluated the routine use of ultrasonography (USG) for active case finding of abdominal TB in HIV clinics...
May 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28506074/primary-peripancreatic-lymph-node-tuberculosis-as-a-differential-diagnosis-of-pancreatic-neoplasia
#4
Nuria García Del Olmo, Andrea Boscà Robledo, Rafael Penalba Palmí, Elena Añón Iranzo, Javier Aguiló Lucía
Primary peripancreatic lymph node tuberculosis is an exceptional entity in immunocompetent patients, but its incidence is increasing in developed countries in recent years due to increasing immigration. It usually presents as a pancreatic mass and is misdiagnosed as pancreatic neoplasia in most cases, with the diagnosis of tuberculosis occurring after surgery. We report the case of a 38 year old Pakistani man with abdominal pain of several months duration, who was initially diagnosed with a pancreatic neoplasm after detecting a mass in the pancreatic isthmus by computed tomography (CT) and abdominal magnetic resonance imaging (MRI)...
May 16, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28506054/-penile-tuberculosis-a-case-report
#5
Takahiro Imanaka, Hironori Nomura, Go Tsujimura, Yoko Ko, Takanori Kinjyo, Iwao Yoshioka, Shingo Takada, Yoko Yahata, Tetsu Mizutani
A 66-year-old man presented with a chief complaint of glans penis pain, induration, and discharge of pus. He was prescribed a course of antibiotics, but the condition persisted despite treatment. Thus, we differrentially diagnosed the patient with penile tuberculosis and pyoderma gangrenosum, and performed a biopsy of the penis. The biopsy result was thickening of the horny layer epidermis with only a foreign body granuloma composed of inflammatory cells, and did not lead to a definitive diagnosis. Thoraca-abdominal computed tomography revealed axillary lymphadenopathy with necrosis...
April 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28500120/the-clinical-conundrum-of-diagnosing-and-treating-systemic-sarcoidosis-in-a-high-tb-burden-area
#6
Krishnadas Thulasidoss, Lavanya Asokan, Piyush Chandra, Pravinkumar Rejliwal
A 53-year-old woman from Southern India presented with weight loss, anorexia, fever and asthenia. Whole body positron emission tomography/computed tomography (PET-CT) showed fluorodeoxyglucose-avid mediastinal and abdominal lymphadenopathy with hepatic, splenic, parotid and lacrimal glandular inflammations. Endoscopic ultrasound-guided fine needle aspiration of subcarinal lymph node showed non-caseating granulomas. Initial serum ACE level was elevated but with normal calcium. Despite the suspicion of sarcoidosis, a trial of antituberculosis therapy was started empirically due to similar presentations of disseminated tuberculosis (TB) in this high endemic area...
May 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28489844/penetrating-gastric-ulcer-as-a-manifestation-of-multisystemic-tuberculosis
#7
Jorge Espinoza-Ríos, Eduar Bravo Paredes, José Pinto Valdivia, Julissa Guevara, Jorge Huerta-Mercado, Martín Tagle Arróspide, Alejandro Bussalleu Rivera
We present the case of a 30-year old female with a history of abdominal pain, fever, poor oral tolerance and weight loss for 6 months. An abdominal CT scan showed marked gastric dilatation due to extrinsic compression from lymphadenopathies around the second portion of the duodenum. The upper endoscopy revealed the presence of a penetrating gastric ulcer in the greater curvature. Biopsies of the lesions showed hystiocytes with granulomatous features and Acid Fast Bacilli (AFB) positive, and the cultures grew Mycobacterium tuberculosis sensitive to Isonazid and Rifampin...
January 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28489769/retroperitoneal-metastatic-poorly-differentiated-carcinoma-with-%C3%AE-human-chorionic-gonadotropin-secretion-presenting-as-a-psoas-abscess-a-case-report-and-review-of-the-literature
#8
Bingjin Wang, Weifang Liu, Zengwu Shao, Xianlin Zeng
RATIONALE: Psoas abscesses generally arise from a contiguous intra-abdominal or pelvic infectious process or hematogenous spreading of bacteria. The serum β-human chorionic gonadotropin has been used to detect normal or ectopic pregnancy. It also can be utilized in following up carcinomas. PATIENT CONCERNS: Here, we reported a case of a 47-year-old woman who presented with a left psoas mass presumptively diagnosed as an abscess secondary to lumbar tuberculosis In addition, the patient had abnormal increase of β-human chorionic gonadotropin...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28489674/differentiation-between-crohn-s-disease-and-intestinal-tuberculosis-in-children
#9
Sumit Kumar Singh, Anshu Srivastava, Niraj Kumari, Ujjal Poddar, Surender Kumar Yachha, Chandra Mani Pandey
OBJECTIVES: To study clinical, endoscopic, radiologic and histopathological features helpful in differentiating Crohn's disease (CD) from intestinal tuberculosis (ITB) in children. METHODS: Patients diagnosed to have CD or ITB based on standard recommended criteria were enrolled. Children with inflammatory bowel disease unclassified or suspected ITB or CD with incomplete work-up or lost to follow-up were excluded. The clinical and laboratory (radiology, endoscopy and histology) details of children were analyzed...
May 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28473931/hematochezia-an-uncommon-presentation-of-colonic-tuberculosis
#10
Fares Ayoub, Vikas Khullar, Harry Powers, Angela Pham, Shehla Islam, Amitabh Suman
Abdominal tuberculosis (TB) is an uncommon entity in the United States. Colonic TB is reported in 2-3% of patients with abdominal TB. It is frequently misdiagnosed as Crohn's disease or carcinoma of the colon due to their shared clinical, radiographic, and endoscopic presentations. We present a case of a 72-year-old male with colonic tuberculosis presenting as hematochezia. Our patient presented with shortness of breath and weight loss. Chest X-ray demonstrated ill-defined bilateral parenchymal opacities in the perihilar, mid, and lower lung zones...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/28458310/peripancreatic-tuberculous-lymphadenitis-diagnosed-via-endoscopic-ultrasound-guided-fine-needle-aspiration-and-polymerase-chain-reaction
#11
Jun Arai, Katsuya Kitamura, Akira Yamamiya, Yu Ishii, Tomohiro Nomoto, Tadashi Honma, Hiroo Ishida, Eisuke Shiozawa, Masafumi Takimoto, Hitoshi Yoshida
We performed endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) on a patient presenting with an asymptomatic peripancreatic mass-like lesion. The aspiration cytologic finding was class II. On positron emission tomography-computed tomography (PET-CT), there were hot spots in the left supra-clavicular lymph node and the peripancreatic lesion. A whole biopsy of the left supra-clavicular lymph node revealed tuberculous lymphadenitis. Polymerase chain reaction (PCR) using tissue obtained via EUS-FNA showed that the peripancreatic mass-like lesion was also positive for tuberculosis...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28435232/self-reported-adherence-and-associated-factors-to-isoniazid-preventive-therapy-for-latent-tuberculosis-among-people-living-with-hiv-aids-at-health-centers-in-gondar-town-north-west-ethiopia
#12
Asnakew Achaw Ayele, Seyfe Asrade Atnafie, Demis Driba Balcha, Asegedech Tsegaw Weredekal, Birhanu Alemayehu Woldegiorgis, Mulgeta Melaku Wotte, Begashaw Melaku Gebresillasie
PURPOSE: This study aimed to assess self-reported adherence and associated factors to isoniazid preventive therapy (IPT) for latent tuberculosis among people living with HIV/AIDS (PLWHA) at health centers in Gondar town, North West Ethiopia. PATIENTS AND METHODS: An institution-based prospective cross-sectional study was conducted from March 10 to June 11, 2016. A total of 154 eligible participants were included in the study, using the simple random sampling method, from the available four health centers and one teaching referral hospital that provided antiretroviral therapy (ART) for HIV/AIDS patients...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28410698/spontaneous-chylothorax-revealing-a-mediastinal-and-abdominal-lymph-node-tuberculosis
#13
Jihen Ben Amar, Haifa Zaibi, Besma Dahri, Hichem Aouina
Chylothorax is a rare manifestation of tuberculosis. We report a case of spontaneous chylothorax due to tuberculosis. A 62-year-old woman was admitted with fever, chest pain and dyspnea. Chest and abdominal computed tomography revealed a fluid collection with necrotic mediastinal and abdominal lymph nodes. Biopsy of lymph nodes by mediastinoscopy. The patient was treated with anti-tuberculosis medication. He is clinically improved and his pleural effusion also completely resolved.
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28410692/treatment-outcome-of-extrapulmonary-tuberculosis-under-revised-national-tuberculosis-control-programme
#14
J J Cherian, I Lobo, A Sukhlecha, U Chawan, N A Kshirsagar, B L Nair, L Sawardekar
BACKGROUND: Extrapulmonary tuberculosis (EPTB) constitutes 15-20% of tuberculosis cases in India. Earlier studies have evaluated treatment outcomes of EPTB with little information on outcomes of individual site of EPTB. AIMS: The objective was to study the outcome of Directly Observed Treatment Short course (DOTS) treatment of EPTB in different organ systems under Revised National Tuberculosis Control Programme. METHODS: Multi-centric retrospectives record review was carried out in three states in India...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28403237/evidence-of-neurofibromatosis-type-1-in-a-multi-morbid-inca-child-mummy-a-paleoradiological-investigation-using-computed-tomography
#15
Stephanie Panzer, Holger Wittig, Stephanie Zesch, Wilfried Rosendahl, Sandra Blache, Magdalena Müller-Gerbl, Gerhard Hotz
OBJECTIVE: In this study, an Inca bundle was examined using computed tomography (CT). The primary aim was to determine the preservation status of bony and soft tissues, the sex, the age at the time of death, possible indicators for disease or even the cause of death, as well as the kind of mummification. A secondary aim was to obtain a brief overview of the wrapping in order to gain additional information on the cultural background. MATERIALS AND METHODS: The bundle belongs to the Museum of Cultures in Basel, Switzerland, and was bought in Munich, Germany, in 1921...
2017: PloS One
https://www.readbyqxmd.com/read/28394836/18f-fdg-pet-ct-of-tuberculosis-meningitis-and-carotid-pseudoaneurysm
#16
Kasturi Rangan, Mudalsha Ravina, Nitin Yadav, Ajay Singh Suraj, Sanjay Gambhir
A 26-year-old woman presented with a headache, left-sided weakness of the body, and pulsatile swelling above the sternal notch. She was treated for abdominal tuberculosis in the past, two years later she developed miliary tuberculosis and was put on modified regimen of antitubercular drugs in view of drug induced hepatitis. Ultrasound neck revealed saccular aneurysm measuring 4 x 3 cm, located in between common carotid arteries with an eccentric thrombus. MRI brain revealed multiple tuberculoma with thick basal meningeal enhancement...
June 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28377878/miliary-tuberculosis-in-a-patient-with-tuberculous-mycotic-aneurysm-of-the-abdominal-aorta-case-report-and-review-of-the-literature
#17
Katerina Manika, Christoforos Efthymiou, Georgios Damianidis, Elisavet Zioga, Eleni Papadaki, Kalliopi Lagoudi, Ioannis Kioumis
The combination of miliary tuberculosis and tuberculous mycotic aneurysm has been described in the literature. We present the case of an 84-year-old man who was diagnosed with a mycotic aneurysm of the abdominal aorta and an adjacent soft tissue mass, after a 3- month history of fever. The patient underwent endovascular restoration of the aneurysm and was treated with broad-spectrum antibiotics. One and a half months later the fever relapsed and the chest CT scan revealed findings consistent with miliary tuberculosis and opacities of both upper lobes not present before, while the abdominal CT scan revealed an increase in the size of the para-aortic mass...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28360466/rare-cause-of-paradoxical-worsening-of-pleural-effusion-in-a-patient-with-tuberculosis
#18
Paramasivan Duraikannan, S Saheer, T Balamugesh, D J Christopher
A 33-year-old patient, Known case of chronic kidney disease on maintenance dialysis presented with complaints of low-grade fever and weight loss of 2 months duration. Computed tomography (CT) revealed bilateral mild pleural effusion with significant mediastinal and abdominal adenopathy. CT-guided fine-needle aspiration cytology of abdominal lymph nodes and bone marrow culture was suggestive of tuberculosis. The patient was started on four drug anti-tubercular therapy, post 6 weeks of initiation he developed new onset fever and chest X-ray revealed moderate right pleural effusion...
March 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28357123/adverse-reactions-to-fluoroquinolones-in-the-nigerian-population-an-audit-of-reports-submitted-to-the-national-pharmacovigilance-centre-from-2004-to-2016
#19
Ibrahim A Oreagba, Kazeem A Oshikoya, Comfort Ogar, Abiodun O Adefurin, Ali Ibrahim, Olufunsho Awodele, Yetunde Oni
Adverse drug reactions (ADRs) recorded in national pharmacovigilance databases in developed countries have been analyzed. However, adverse reactions to fluoroquinolones were observed globally despite their wide use and safety concerns. We provided information on the pattern of adverse reactions to fluoroquinolones reported spontaneously to the National Pharmacovigilance Centre (NPC), Nigeria. ADRs to fluoroquinolones reported to the NPC, over a period of 12 years, were analyzed. Evaluation was done for annual reports, age and gender of patients, type of reporter, suspected fluoroquinolones and adverse reactions, onset and outcome of ADRs, and causality...
April 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28357060/visceral-scalloping-on-abdominal-computed-tomography-due-to-abdominal-tuberculosis
#20
Vishal Sharma, Anmol Bhatia, Sarthak Malik, Navjeet Singh, Surinder S Rana
OBJECTIVE: Scalloping of visceral organs is described in pseudomyxoma peritonei, malignant ascites, among other conditions, but not tuberculosis. METHODS: We report findings from a retrospective study of patients with abdominal tuberculosis who had visceral scalloping on abdominal computed tomography (CT). Diagnosis of abdominal tuberculosis was made on the basis of combination of clinical, biochemical, radiological and microbiological criteria. The clinical data, hematological and biochemical parameters, and findings of chest X-ray, CT, Mantoux test, and HIV serology were recorded...
January 2017: Therapeutic Advances in Infectious Disease
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