keyword
MENU ▼
Read by QxMD icon Read
search

hypothyroidism subclinical treatment

keyword
https://www.readbyqxmd.com/read/28853052/thyroid-diseases-and-bone-health
#1
REVIEW
G R Williams, J H D Bassett
Thyroid hormones are essential for skeletal development and are important regulators of bone maintenance in adults. Childhood hypothyroidism causes delayed skeletal development, retarded linear growth and impaired bone mineral accrual. Epiphyseal dysgenesis is evidenced by classic features of stippled epiphyses on X-ray. In severe cases, post-natal growth arrest results in a complex skeletal dysplasia. Thyroid hormone replacement stimulates catch-up growth and bone maturation, but recovery may be incomplete dependent on the duration and severity of hypothyroidism prior to treatment...
August 29, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28829155/efficacy-and-safety-of-ashwagandha-root-extract-in-subclinical-hypothyroid-patients-a-double-blind-randomized-placebo-controlled-trial
#2
Ashok Kumar Sharma, Indraneel Basu, Siddarth Singh
BACKGROUND: Subclinical hypothyroidism, a thyroid disorder without obvious symptoms of thyroid deficiency, occurs in 3%-8% of the global population. Ashwagandha [Withania somnifera (L.) Dunal], a traditional medicine in Ayurveda, is often prescribed for thyroid dysfunctions. OBJECTIVE: This pilot study was designed to evaluate the efficacy and safety of ashwagandha root extract in subclinical hypothyroid patients. DESIGN, SETTING, AND PARTICIPANTS: A prospective, randomized, double-blind, single-center placebo-controlled study was performed at Sudbhawana Hospital, Varanasi, India between May 2016 and September 2016...
August 22, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28767416/effect-of-subclinical-hypothyroidism-on-the-skeletal-system-and-improvement-with-short-term-thyroxine-therapy
#3
Cuixia Gao, Yu Wang, Tingting Li, Jing Huang, Limin Tian
The purpose of the study was to observe changes in the skeletal system of rats with subclinical hypothyroidism (SCH) and to determine whether L-thyroxine (L-T4) administration suppresses those changes. Sixty male Wistar rats were randomly divided into control, SCH, and SCH+T4 groups. SCH was induced in rats by administration of methimazole (MMI), and rats in the SCH+T4 group were treated with L-T4 after 45 days of MMI administration. The SCH group had higher thyroid-stimulating hormone (TSH) level than the control and SCH+T4 groups...
July 26, 2017: Oncotarget
https://www.readbyqxmd.com/read/28754607/reversal-of-nocturnal-non-dipping-of-blood-pressure-after-levothyroxine-therapy-in-patients-with-subclinical-hypothyroidism
#4
Mannmath Nath, Balram Gupta, Madhukar Rai, Surya K Singh
AIMS: To study the loss of diurnal variation in blood pressure in normotensive patients with Subclinical/overt hypothyroidism and effect of Levothyroxine (L-T4) treatment. MATERIALS AND METHODS: In this interventional study Eighty patients between 17- 50 years with newly detected OH and SCH (74 women and 6 men) and nine euthyroid subjects (all men) with blood pressure <140/90 were recruited. All patients underwent 24h ambulatory blood pressure monitoring (ABPM) using ABPM machine before and after treatment with L-T4...
July 20, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28740582/hypothyroidism-and-the-heart
#5
Maja Udovcic, Raul Herrera Pena, Bhargavi Patham, Laila Tabatabai, Abhishek Kansara
Hypothyroidism is a commonly encountered clinical condition with variable prevalence. It has profound effects on cardiac function that can impact cardiac contractility, vascular resistance, blood pressure, and heart rhythm. With this review, we aim to describe the effects of hypothyroidism and subclinical hypothyroidism on the heart. Additionally, we attempt to briefly describe how hypothyroid treatment affects cardiovascular parameters.
April 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/28724185/myo-inositol-plus-selenium-supplementation-restores-euthyroid-state-in-hashimoto-s-patients-with-subclinical-hypothyroidism
#6
M Nordio, S Basciani
OBJECTIVE: Clinical evidence suggests that oral supplementation with myo-inositol (MI) and selenium (Se) is useful in the treatment of autoimmune thyroiditis. The purpose of this study was to highlight the positive response of Hashimoto's patients with subclinical hypothyroidism (SH) treated with MI and Se (MI-Se) in restoring a normal thyroid function. PATIENTS AND METHODS: A total of 168 patients with Hashimoto's thyroiditis (HT) having Thyroid Stimulating Hormone (TSH) levels between 3 and 6 µIU/ml were randomized into 2 groups: one receiving MI-Se and the other one Se alone...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28724175/myo-inositol-and-selenium-reduce-the-risk-of-developing-overt-hypothyroidism-in-patients-with-autoimmune-thyroiditis
#7
S M Ferrari, P Fallahi, F Di Bari, R Vita, S Benvenga, A Antonelli
OBJECTIVE: The beneficial effects obtained by myo-inositol in association with seleno-methionine in patients affected by subclinical hypothyroidism have been recently demonstrated. Here, we evaluate the immune-modulating effect of myo-inositol in association with seleno-methionine in patients with euthyroid autoimmune thyroiditis (AT). PATIENTS AND METHODS: Twenty-one consecutive Caucasian patients with newly diagnosed euthyroid chronic AT were evaluated. All subjects were treated with myo-inositol in association with selenium (600 mg/83 mg) tablets, twice per day, for six months...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28716808/second-trimester-levothyroxine-treatment-for-subclinical-hypothyroidism-or-hypothyroxinaemia-of-pregnancy-does-not-improve-cognitive-outcomes-of-children
#8
Alex Stagnaro-Green
No abstract text is available yet for this article.
August 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28683860/latent-hypothyroidism-in-adults
#9
Jeannine Schübel, Joachim Feldkamp, Antje Bergmann, Wolfgang Drossard, Karen Voigt
BACKGROUND: The prevalence of latent/subclinical hypothyroidism is between 3% and 10%, according to epidemiologic studies that have been carried out in the USA, the United Kingdom, and Denmark. As persons with latent hypo - thyroidism are often asymptomatic, the diagnosis is often made incidentally in routine laboratory testing. METHODS: This review is based on a selective search in PubMed for publications on the diagnosis and treatment of latent hypothyroidism...
June 23, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28674524/psoriasis-psoriatic-arthritis-and-thyroid-autoimmunity
#10
REVIEW
Ilaria Ruffilli, Francesca Ragusa, Salvatore Benvenga, Roberto Vita, Alessandro Antonelli, Poupak Fallahi, Silvia Martina Ferrari
Psoriasis (PsO) is a chronic relapsing/remitting autoimmune skin disease, associated with an increased risk of other autoimmune disorders. Psoriatic arthritis (PsA) is a chronic inflammatory arthritis occurring approximately in 30% of PsO patients. Sporadic cases of association between PsO and autoimmune thyroid disorders (AITDs) have been reported. However, two different recent studies did not find any association between them. In patients with PsO and PsA, an association with AITD has been shown by most of the studies in adults, but not in the juvenile form...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28638825/thyroid-dysfunction-in-non-interferon-treated-hepatitis-c-patients-residing-in-hepatitis-endemic-area
#11
Nayab Batool, Shan Elahi, Nazish Saleem, Abrar Ashraf
BACKGROUND: Association of thyroid dysfunction (TD) with interferon treatment of HCV is well known to clinicians. However, a few studies have highlighted the role of hepatitis C virus per se in the development of TD. The aim of this study was to know the prevalence of TD in non-interferon treated HCV infected patients referred for thyroid function testing. PATIENTS AND METHODS: Among 557 ELISA-positive HCV patients 446 (341 females, 105 males) were selected for this study...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28617535/research-on-the-protective-effects-of-antioxidants-on-metabolic-syndrome-induced-by-thyroid-dysfunction
#12
Y Chen, Z Zhou, X-X Li, T Wang
OBJECTIVE: This paper researches on the protective effects of antioxidants on metabolic syndrome induced by thyroid dysfunction. While the role of Lipoic acid (LA), Resveratrol (R) and Quercetin (Q) are recognized, the mechanisms for their ameliorative effects are partially understood. Therefore, the objective of this study was to determine the prevalence of MS among university workers and to examine the relationship with thyroid function and mechanisms for protective effects of LA, Resveratrol and Quercetin on the heart, kidneys and lungs...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28615186/subclinical-hypothyroidism-in-paediatric-population-treated-with-levothyroxine-a-real-world-study-on-2001-2014-italian-administrative-data
#13
Nella Augusta Greggio, Elisa Rossi, Silvia Calabria, Alice Meneghin, Joaquin Gutierrez de Rubalcava, Carlo Piccinni, Antonella Pedrini
OBJECTIVE: To estimate the prevalence of subclinical hypothyroidism (SH) among children, by using levothyroxine low dosage as disease proxy, and to describe prescription pattern. DESIGN: An historical cohort study was performed through administrative databases of 12 Italian Local Health Units covering 3,079,141 inhabitants. A cohort of children (aged 0-13 years) was selected in the period 2001-2014. A subgroup of new users (aged 0-9 years) was identified and followed up for 5 years...
August 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28609832/pembrolizumab-induced-thyroiditis-comprehensive-clinical-review-and-insights-into-underlying-involved-mechanisms
#14
Danae A Delivanis, Michael P Gustafson, Svetlana Bornschlegl, Michele M Merten, Lisa Kottschade, Sarah Withers, Allan B Dietz, Mabel Ryder
Context: Thyroid immune-related adverse events (irAEs) in patients treated with programmed death receptor-1 (PD-1) blockade are increasingly recognized as one of the most common adverse effects. Our aim was to determine the incidence and examine the potential mechanisms of anti-PD-1-induced thyroid irAEs. Design: Single-center, retrospective cohort study. Patients and Measurements: We studied 93 patients with advanced cancer (ages 24 to 82 years; 60% males) who received at least one infusion of pembrolizumab...
August 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28590917/serum-levels-of-nitrite-nitrate-lipid-profile-and-fasting-plasma-glucose-and-their-associations-in-subclinical-hypothyroid-women-before-and-after-a-two-month-treatment-by-levothyroxine
#15
Mohammad Mostakhdem Hashemi, Elahe Kosari, Azad Reza Mansourian, Abdoljalal Marjani
BACKGROUND: Subclinical hypothyroidism (sHT) is a condition defined by elevated TSH values with normal levels of free thyroid hormones. Altered metabolic status is one of the consequences of sHT which can affect serum levels of FPG, lipid profile, and nitric oxide which propounds cardiovascular consequences per se. The aim of this study was to determine the possible effects of sHT on nitrite/nitrate levels, as a marker of endothelial performance. MATERIALS AND METHODS: 50 females were enrolled in this study, 25 women as control group and 25 women as case group (evaluated two times: before and after levothyroxine therapy)...
June 1, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28566564/effect-of-thyroxin-treatment-on-carotid-intima-media-thickness-cimt-reduction-in-patients-with-subclinical-hypothyroidism-sch-a-meta-analysis-of-clinical-trials
#16
Muhammad Aziz, Yugandhar Kandimalla, Archana Machavarapu, Anshul Saxena, Sankalp Das, Adnan Younus, Michelle Nguyen, Rehan Malik, Dixitha Anugula, Muhammad A Latif, Choudhry Humayun, Idrees M Khan, Ali Adus, Aisha Rasool, Emir Veledar, Khurram Nasir
AIM: Research shows that subclinical hypothyroidism (SCH) is related to an increased carotid intima-media thickness (CIMT), a surrogate marker of subclinical cardiovascular disease (CVD). It is controversial whether or not SCH should be treated to reduce CVD morbidity and mortality. This meta-analysis aimed to determine whether SCH is associated with an increase in CIMT as compared to Euthyroidism (EU) and whether thyroxin (T4) treatment in SCH can reverse the change in CIMT. METHODS: Two independent reviewers conducted an extensive database research up to December 2016...
July 1, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28566447/management-of-endocrine-disease-l-thyroxine-replacement-therapy-in-the-frail-elderly-a-challenge-in-clinical-practice
#17
REVIEW
R M Ruggeri, F Trimarchi, B Biondi
The number of elderly people, mostly aged over 85 years (the 'oldest old'), is increasing worldwide. As a consequence, accompanying morbidity and disability have been increasing, and frailty, defined as an age-related condition of decline of physiological reserves and vulnerability, represents an emerging problem. Caring for older frail people may represent a challenge, since the elderly differ significantly from younger adults in terms of comorbidity, polypharmacy, pharmacokinetics and greater vulnerability to adverse drug reactions...
October 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28561265/mild-tsh-resistance-clinical-and-hormonal-features-in-childhood-and-adulthood
#18
Maria Cristina Vigone, Marianna Di Frenna, Fabiana Guizzardi, Giulia Gelmini, Tiziana de Filippis, Stefano Mora, Silvana Caiulo, Micol Sonnino, Marco Bonomi, Luca Persani, Giovanna Weber
OBJECTIVE: Mutations in TSH receptor (TSHR) are associated with TSH resistance, a genetic defect characterized by a heterogeneous phenotype ranging from severe hypothyroidism to subclinical hypothyroidism (SCH). We assessed the clinical and hormonal pattern of TSHR variants in a series of pediatric patients, and the long-term outcome of growth, biochemical measurements of metabolism, and neuropsychological functions in TSHR mutations carriers. DESIGN: Observational, retrospective study...
May 31, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28545515/outcome-of-in-vitro-fertilization-in-women-with-subclinical-hypothyroidism
#19
YunYing Cai, LanPing Zhong, Jie Guan, RuiJin Guo, Ben Niu, YanPing Ma, Heng Su
BACKGROUND: Previous studies examining associations between subclinical hypothyroidism (SCH) with in vitro fertilization (IVF) outcome indicate some benefits of levothyroxine (LT4) treatment. But IVF outcomes in treated SCH women whose serum Thyroid Stimulating Hormone (TSH) concentration did and did not exceed 2.5 mIU/L before the IVF cycle has not been studied thoroughly. METHODS: In this study, we performed a prospective cohort study with 270 treated subclinical hypothyroidism patients undergoing their first IVF retrieval cycle at a single cite...
May 25, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/28540785/single-session-high-intensity-focussed-ablation-hifu-versus-open-cervical-hemithyroidectomy-for-benign-thyroid-nodule-analysis-on-early-efficacy-safety-and-voice-quality
#20
Brian H H Lang, Carlos K H Wong, Estella P M Ma
BACKGROUND: High intensity focussed ultrasound (HIFU) is a promising non-surgical treatment for symptomatic benign thyroid nodule. We aimed to compare early efficacy, safety and voice quality between HIFU ablation and open thyroidectomy. METHODS: Consecutive patients who underwent single-session HIFU ablation or a hemithyroidectomy for symptomatic benign thyroid nodule were included. The 6-month extent of nodule shrinkage, symptom improvement score, thyroid function, hospital stay and cost were compared between the two procedures...
March 24, 2017: International Journal of Hyperthermia
keyword
keyword
75769
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"