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https://www.readbyqxmd.com/read/28343061/automated-diabetic-macular-edema-dme-grading-system-using-dwt-dct-features-and-maculopathy-index
#1
U Rajendra Acharya, Muthu Rama Krishnan Mookiah, Joel E W Koh, Jen Hong Tan, Sulatha V Bhandary, A Krishna Rao, Yuki Hagiwara, Chua Kuang Chua, Augustinus Laude
The cause of diabetic macular edema (DME) is due to prolonged and uncontrolled diabetes mellitus (DM) which affects the vision of diabetic subjects. DME is graded based on the exudate location from the macula. It is clinically diagnosed using fundus images which is tedious and time-consuming. Regular eye screening and subsequent treatment may prevent the vision loss. Hence, in this work, a hybrid system based on Radon transform (RT), discrete wavelet transform (DWT) and discrete cosine transform (DCT) are proposed for an automated detection of DME...
March 19, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28317986/experimental-and-theoretical-evidence-for-the-ferromagnetic-edge-in-wse2-nanosheets
#2
Lei Tao, Fanchen Meng, Shudong Zhao, Yongli Song, Jianxin Yu, Xianjie Wang, Zhiguo Liu, Yi Wang, Bingsheng Li, Yang Wang, Yu Sui
Bulk TMDCs are diamagnetic materials; however, two-dimensional TMDCs exhibit spin polarized edge states, which results in a coupling between the unsaturated transition metal and chalcogenide atoms at the edges. The magnetism in two-dimensional TMDCs broadens their applications in spintronic and multi-functional devices. Herein, by combining macro/micro-magnetic experimental measurements and density functional theory (DFT) calculations, we demonstrate that among five possible edge-terminated WSe2 nanosheets only two types have a magnetic ground state, corresponding to the 100% Se edge terminated and 50% Se edge terminated nanosheets, respectively...
March 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28317202/cooperative-magnetism-in-crystalline-n-aryl-substituted-verdazyl-radicals-first-principles-predictions-and-experimental-results
#3
Steffen Eusterwiemann, Thomas Dresselhaus, Carsten Doerenkamp, Oliver Janka, Oliver Niehaus, Anja Massolle, Constantin Daniliuc, Hellmut Eckert, Rainer Pöttgen, Johannes Neugebauer, Armido Studer
We report on a series of eight diaryl-6-oxo-verdazyl radicals containing a tert-butyl group at the C(3) position regarding their crystal structure and magnetic properties by means of magnetic susceptibility measurements in combination with quantum chemical calculations using the first-principles bottom-up approach. The latter method allows for a qualitative prediction and detailed analysis of the correlation between solid state architecture and magnetic properties. Although the perturbation in the molecular structure by varying the substituent of the N-aryl-ring may appear small, the effects upon the structural parameters controlling intermolecular magnetic coupling interactions are strong, resulting in a wide spectrum of cooperative magnetic behavior...
March 20, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28278439/a-case-of-single-incision-laparoscopic-surgery-for-a-bleeding-meckel-s-diverticulum-diagnosed-pre-operatively-by-double-balloon-endoscopy
#4
Toshio Shiraishi, Tetsuro Tominaga, Takashi Nonaka, Kouki Wakata, Masaki Kunizaki, Shuichi Tobinaga, Yorihisa Sumida, Shigekazu Hidaka, Naoe Kinoshita, Terumitsu Sawai, Takeshi Nagayasu
INTRODUCTION:  Meckel's diverticulum (MD) is a congenital true diverticulum that is residual yolk duct tissue, and some cases with complications require surgery. It has been reported that laparoscopic surgery is effective for patients with an MD. PRESENTATION OF CASE: A 79-year-old man with melena visited our hospital. Upper gastrointestinal series and colonoscopy showed no bleeding lesion. Double-balloon endoscopy was then performed to examine the small intestine...
February 22, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28276656/a-dimeric-bis-melamine-substituted-bispidine-for-efficient-transmembrane-h-cl-cotransport
#5
Sopan Valiba Shinde, Pinaki Talukdar
A 3,7-diazabicyclo[3.3.1]nonane linking to two melamines is a unique transmembrane H(+) /Cl(-) carrier. In the solid state, the V-shaped compound forms a HCl-bound zig-zag network through cooperative protonation and hydrogen bond interactions. In the lipid membrane, the receptor forms a dimeric self-assembly involving multiple H(+) and Cl(-) leading to the efficient transport of the acid. The pH-dependent Cl(-) efflux observed for the compound was rationalized based on a gradual protonation model that confers an active transmembrane carrier at physiological pH...
March 9, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28262871/from-single-atoms-to-self-assembled-quantum-single-atomic-nanowires-noble-metal-atoms-on-black-phosphorene-monolayers
#6
X J Zhao, Wen-Wen Shan, Hao He, Xinlian Xue, Z X Guo, S F Li
Transition metal (TM) nanostructures, such as one dimensional (1D) nanowires with/without substrates, usually possess drastically different properties from their bulk counterparts, due to their distinct stacking and electronic confinement. Correspondingly, it is of great importance to establish the dominant driving force in forming 1D single-metal-atom-wires (SMAWs). Here, with first-principles calculations, taking the black phosphorene (BP) monolayer as a prototype 2D substrate, we investigate the energetic and kinetic properties of all the 5d-TM atoms on the 2D substrate to reveal the mechanism of formation of SMAWs...
March 6, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28249176/identification-of-potential-serum-biomarkers-in-pigs-at-early-stage-after-lipopolysaccharide-injection
#7
Chao Yin, Weifeng Liu, Zhiqing Liu, Yanping Huang, Le Ci, Ruqian Zhao, Xiaojing Yang
The identification of useful biological indicators to monitor the body response before the presentation of clinical diseases has practical value in livestock production. To identify potential biomarkers in pigs at the early stage during inflammation, 12 pigs were intramuscularly injected with 2mL of Lipopolysaccharide (LPS, 15μg/kg BW) or saline. Serum protein expression profiles were detected with two-dimensional electrophoresis (2-DE) and matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) techniques...
February 17, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28207795/organ-dysfunction-during-continuous-veno-venous-high-cut-off-hemodialysis-in-patients-with-septic-acute-kidney-injury-a-prospective-observational-study
#8
Gianluca Villa, Cosimo Chelazzi, Elena Morettini, Lucia Zamidei, Serafina Valente, A Lucia Caldini, Giovanni Zagli, A Raffaele De Gaudio, Stefano Romagnoli
BACKGROUND: Continuous veno-venous hemodialysis with high cut-off membranes (HCO-CVVHD) removes inflammatory mediators involved in organ dysfunction during sepsis. The aim of the present study was to assess the variations in SOFA score and identify early predictors of short-term mortality in a cohort of patients with septic shock, treated with HCO-CVVHD for acute kidney injury (AKI). METHODS: An observational prospective multicenter cohort study was conducted in four mixed medical-surgical ICUs...
2017: PloS One
https://www.readbyqxmd.com/read/28206753/charge-density-wave-in-the-new-polymorphs-of-re2ru3ge5-re-pr-sm-dy
#9
Daniel E Bugaris, Christos D Malliakas, Fei Han, Nicholas P Calta, Mihai Sturza, Matthew J Krogstad, Raymond Osborn, Stephan Rosenkranz, Jacob P C Ruff, Giancarlo Trimarchi, Sergey L Bud'ko, Mahalingam Balasubramanian, Duck Young Chung, Mercouri G Kanatzidis
A new polymorph of the RE2Ru3Ge5 (RE = Pr, Sm, Dy) compounds has been grown as single crystals via an indium flux. These compounds crystallize in tetragonal space group P4/mnc with the Sc2Fe3Si5-type structure, having lattice parameters a = 11.020(2) Å and c = 5.853(1) Å for RE = Pr, a = 10.982(2) Å and c = 5.777(1) Å for RE = Sm, and a = 10.927(2) Å and c = 5.697(1) Å for RE = Dy. These materials exhibit a structural transition at low temperature, which is attributed to an apparent charge density wave (CDW)...
March 8, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28198600/relationship-between-field-tests-and-match-running-performance-in-high-level-young-brazilian-soccer-players
#10
Rodrigo Aquino, Luiz H Palucci Vieira, Lucas de Paula Oliveira, Luiz G Cruz Goncalves, Paulo R Pereira Santiago
BACKGROUND: The main aim of this study was to analyse the relationship between field tests and match running performance using computational tracking technology in high-level young Brazilian soccer players. METHODS: Twenty-five young male Brazilian soccer players participated in this study (U-15, n = 13; U-17, n = 12). In the same week the players were submitted to field tests and actual matches. The field tests were: Maximum Speed (10m-30m), Zig-Zag, Running-based Anaerobic Sprint Test, and Yo-Yo Intermittent Recovery Test level 1...
February 14, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28198379/large-positive-in-plane-magnetoresistance-induced-by-localized-states-at-nanodomain-boundaries-in-graphene
#11
Han-Chun Wu, Alexander N Chaika, Ming-Chien Hsu, Tsung-Wei Huang, Mourad Abid, Mohamed Abid, Victor Yu Aristov, Olga V Molodtsova, Sergey V Babenkov, Yuran Niu, Barry E Murphy, Sergey A Krasnikov, Olaf Lübben, Huajun Liu, Byong Sun Chun, Yahya T Janabi, Sergei N Molotkov, Igor V Shvets, Alexander I Lichtenstein, Mikhail I Katsnelson, Ching-Ray Chang
Graphene supports long spin lifetimes and long diffusion lengths at room temperature, making it highly promising for spintronics. However, making graphene magnetic remains a principal challenge despite the many proposed solutions. Among these, graphene with zig-zag edges and ripples are the most promising candidates, as zig-zag edges are predicted to host spin-polarized electronic states, and spin-orbit coupling can be induced by ripples. Here we investigate the magnetoresistance of graphene grown on technologically relevant SiC/Si(001) wafers, where inherent nanodomain boundaries sandwich zig-zag structures between adjacent ripples of large curvature...
February 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28195288/slip-divergence-of-water-flow-in-graphene-nanochannels-the-role-of-chirality
#12
Enrique Wagemann, Elton Oyarzua, Jens H Walther, Harvey A Zambrano
Graphene has attracted considerable attention due to its characteristics as a 2D material and its fascinating properties, providing a potential building block for nanofabrication. In nanochannels the solid-liquid interface plays a non-negligible role in determining the fluid dynamics. Therefore, for an optimal design of nanofluidic devices, a comprehensive understanding of the slippage in a water flow confined between graphene walls is important. In nanoconfinement, experimental and computational studies have found the slip length to increase nonlinearly when the shear rate is larger than a critical value...
February 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28179428/breaking-confinement-unconventional-peptide-presentation-by-major-histocompatibility-mhc-class-i-allele-hla-a-02-01
#13
Soumya G Remesh, Massimo Andreatta, Ge Ying, Thomas Kaever, Morten Nielsen, Curtis McMurtrey, William Hildebrand, Bjoern Peters, Dirk M Zajonc
Peptide antigen-presentation by Major Histocompatibility Class (MHC) I proteins initiates CD8+ T cell mediated immunity against pathogens and cancers. MHC I molecules typically bind peptides with nine amino acids in length with both ends tucked inside the major A and F binding pocket. It has been known for a while that longer peptides can also bind by either bulging out of the groove in the middle of the peptide or by binding in a zig-zag fashion inside the groove. In a recent study, we identified an alternative binding conformation of naturally occurring peptides from Toxoplasma gondii bound by HLA-A*02:01...
February 8, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28135276/binding-of-dna-bending-non-histone-proteins-destabilizes-regular-30-nm-chromatin-structure
#14
Gaurav Bajpai, Ishutesh Jain, Mandar M Inamdar, Dibyendu Das, Ranjith Padinhateeri
Why most of the in vivo experiments do not find the 30-nm chromatin fiber, well studied in vitro, is a puzzle. Two basic physical inputs that are crucial for understanding the structure of the 30-nm fiber are the stiffness of the linker DNA and the relative orientations of the DNA entering/exiting nucleosomes. Based on these inputs we simulate chromatin structure and show that the presence of non-histone proteins, which bind and locally bend linker DNA, destroys any regular higher order structures (e.g., zig-zag)...
January 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/27989540/assessing-postoperative-acute-kidney-injury-in-high-risk-patients-undergoing-major-abdominal-surgery-author-s-reply
#15
Stefano Romagnoli, Giovanni Zagli, Zaccaria Ricci
No abstract text is available yet for this article.
February 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/27982256/effect-of-curcumin-on-visfatin-and-zinc-%C3%AE-2-glycoprotein-in-a-rat-model-of-non-alcoholic-fatty-liver-disease
#16
Changping Li, Juehong Li, Yun Chen, Xiaolin Zhong, Min Kang
PURPOSE: To investigate the effect of curcumin on visfatin and zinc-α2-glycoprotein (ZAG) expression levels in rats with non-alcoholic fatty liver disease (NAFLD). METHODS: Fifty-six male rats were randomly divided into a control group (n=16) and model group (n=40) and were fed on a normal diet or a high-fat diet, respectively. Equal volumes of sodium carboxymethyl cellulose (CMC) were intragastrically administered to the control group for 4 weeks. At the end of the 12th week, visfatin and ZAG protein expression levels were examined by immunohistochemistry...
November 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27968777/noninvasive-epicardial-and-endocardial-electrocardiographic-imaging-of-scar-related-ventricular-tachycardia
#17
Linwei Wang, Omar A Gharbia, B Milan Horáček, John L Sapp
BACKGROUND: The majority of life-threatening ventricular tachycardias (VTs) are sustained by heterogeneous scar substrates with narrow strands of surviving tissue. An effective treatment for scar-related VT is to modify the underlying scar substrate by catheter ablation. If activation sequence and entrainment mapping can be performed during sustained VT, the exit and isthmus of the circuit can often be identified. However, with invasive catheter mapping, only monomorphic VT that is hemodynamically stable can be mapped in this manner...
November 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27924127/ssr-based-genetic-diversity-of-pigmented-and-aromatic-rice-oryza-sativa-l-genotypes-of-the-western-himalayan-region-of-india
#18
Humaira Ashraf, Amjad M Husaini, M Ashraf Bhat, G A Parray, Salim Khan, Nazir A Ganai
A set of 24 of SSR markers were used to estimate the genetic diversity in 16 rice genotypes found in Western Himalayas of Kashmir and Himachal Pradesh, India. The level of polymorphism among the genotypes of rice was evaluated from the number of alleles and PIC value for each of the 24 SSR loci. A total of 68 alleles were detected across the 16 genotypes through the use of these 24 SSR markers The number of alleles per locus generated varied from 2 (RM 338, RM 452, RM 171) to 6 (RM 585, RM 249, RM 481, RM 162)...
October 2016: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/27916958/catalytic-performance-of-a-new-1d-cu-ii-coordination-polymer-cu-no%C3%A2-h%C3%A2-o-htae-4-4-bpy-for-knoevenagel-condensation
#19
Edurne S Larrea, Roberto Fernández de Luis, María I Arriortua
The {Cu(NO₃)(H₂O)}(HTae)(4,4'-Bpy) (H₂Tae = 1,1,2,2-tetraacetylethane, 4,4'-Bpy = 4,4'-Dipyridyl) 1D coordination polymer has been obtained by slow evaporation. The crystal structure consists of parallel and oblique {Cu(HTae)(4,4'-Bpy)} zig-zag metal-organic chains stacked along the [100] crystallographic direction. Copper(II) ions are in octahedral coordination environment linked to two nitrogen atoms of two bridging 4,4'-Bpy and to two oxygen atoms of one HTae molecule in the equatorial plane. The occupation of the axial positions varies from one copper atom to another, with different combinations of water molecules and nitrate anions, giving rise to a commensurate super-structure...
December 1, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27886218/revisiting-the-fear-of-snakes-in-children-the-role-of-aposematic-signalling
#20
Jérémie Souchet, Fabien Aubret
Why humans fear snakes is an old, yet unresolved debate. Its innate origin from evolutionary causes is debated against the powerful influence early experience, culture, media and religion may have on people's aversion to snakes. Here we show that the aversion to snakes in human beings may have been mistaken for an aversion to aposematic signals that are commonly displayed by snakes. A total of 635 children were asked to rate single item images as "nice" or "mean". Snakes, pets and smiley emoticon items were not rated as "mean" unless they displayed subtle aposematic signals in the form of triangular (rather than round) shapes...
November 25, 2016: Scientific Reports
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