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https://www.readbyqxmd.com/read/28621798/the-relationship-of-serum-adipokines-with-malnutrition-inflammation-score-in-hemodialysis
#1
Elham Alipoor, Ahmad Esmaillzadeh, Mitra Mahdavi-Mazdeh, Mehdi Yaseri, Narges Sadat Zahed, Mohammad Javad Hosseinzadeh-Attar
BACKGROUND: Protein-energy wasting is a prevalent disorder in hemodialysis. Zinc-α2-glycoprotein (ZAG) and adipose triglyceride lipase (ATGL) are novel adipokines with recognized lipolytic effects and proposed role in metabolic homeostasis. This study was conducted to investigate the association of ZAG and ATGL concentrations with malnutrition inflammation score (MIS) and metabolic profile of patients with hemodialysis. MATERIALS AND METHODS: Eighty-eight patients under regular hemodialysis divided based on MIS to normal to mild wasting (NMW; n=35) or moderate wasting (MW; n=53) groups...
June 16, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28618229/staggered-linear-assembly-of-spherical-cap-colloids
#2
Yogesh Shelke, Manigandan Sabapathy, Ethayaraja Mani
Linear assembly of colloidal particles is of fundamental interest in visualizing polymer dynamics and living organisms. We have developed a fluid-fluid interface based method to synthesize spherical-cap polymeric latex particles. These particles are shown to spontaneously self-assemble in zig-zag arrangement. The linear assembly is induced due to the shape anisotropy (one side is curved and the other side is nearly-flat) and heterogeneous charge distribution on the particle surfaces. The necessities of these conditions are justified within the framework of DLVO theory...
June 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28615706/channel-branching-and-zigzagging-in-negative-cloud-to-ground-lightning
#3
Rubin Jiang, Xiushu Qie, Hongbo Zhang, Mingyuan Liu, Zhuling Sun, Gaopeng Lu, Zhichao Wang, Yu Wang
A fundamental question in lightning flash concerns why the discharge channel propagates in a zig-zag manner and produces extensive branches. Here we report the optical observation of two negative cloud-to-ground lightning discharges with very high temporal resolution of 180,000 frames per second, which shows in detail the dependence of channel branching and tortuous behavior on the stepping process of the leader development. It is found that the clustered space leaders formed in parallel ahead of the channel tip during an individual step process...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28576733/neuronal-zinc-%C3%AE-2-glycoprotein-is-decreased-in-temporal-lobe-epilepsy-in-patients-and-rats
#4
Ying Liu, Teng Wang, Xi Liu, Xin Wei, Tao Xu, Maojia Yin, Xueying Ding, Lijuan Mo, Lifen Chen
Zinc-α2-glycoprotein (ZAG) is a 42-kDa protein encoded by the AZGP1 gene that is known as a lipid mobilizing factor and is highly homologous to major histocompatibility complex class I family molecules. Recently, transcriptomic research has shown that AZGP1 expression is reduced in the brain tissue of epilepsy patients. However, the cellular distribution and biological role of ZAG in the brain and epilepsy are unclear. Patients with refractory temporal lobe epilepsy (TLE) and brain trauma were included in this study, and pentylenetetrazole (PTZ)-kindled rats were also used...
May 31, 2017: Neuroscience
https://www.readbyqxmd.com/read/28562544/endoscopic-management-of-massive-mercury-ingestion-a-case-report
#5
Levente Zag, Gábor Berkes, Irma F Takács, Attila Szepes, István Szabó
RATIONALE: Ingestion of a massive amount of metallic mercury was thought to be harmless until the last century. After that, in a number of cases, mercury ingestion has been associated with appendicitis, impaired liver function, memory deficits, aspiration leading to pneumonitis and acute renal failure. Treatment includes gastric lavage, giving laxatives and chelating agents, but rapid removal of metallic mercury with gastroscopy has not been used. PATIENT CONCERNS: An 18-year-old man was admitted to our emergency department after drinking 1000 g of metallic mercury as a suicide attempt...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28559427/effects-of-altered-sagittal-trunk-orientation-on-kinetic-pattern-in-able-bodied-walking-on-uneven-ground
#6
Soran Aminiaghdam, Christian Rode
Studies of disturbed human locomotion often focus on the dynamics of the gait when either posture, movement or surface is perturbed. Yet, the interaction effects of variation of trunk posture and ground level on kinetic behaviour of able-bodied gait have not been explored. For twelve participants we investigated the kinetic behaviour as well as velocity and contact time across four steps including an unperturbed step on level ground, pre-perturbation, perturbation (10 cm drop) and post-perturbation steps while walking with normal speed with four postures: regular erect, with 30°, 50° and maximal sagittal trunk flexion (70°)...
May 30, 2017: Biology Open
https://www.readbyqxmd.com/read/28550764/mechanical-properties-of-crossed-lamellar-structures-in-biological-shells-a-review
#7
REVIEW
X W Li, H M Ji, W Yang, G P Zhang, D L Chen
The self-fabrication of materials in nature offers an alternate and powerful solution towards the grand challenge of designing advanced structural materials, where strength and toughness are always mutually exclusive. Crossed-lamellar structures are the most common microstructures in mollusks that are composed of aragonites and a small amount of organic materials. Such a distinctive composite structure has a fracture toughness being much higher than that of pure carbonate mineral. These structures exhibiting complex hierarchical microarchitectures that span several sub-level lamellae from microscale down to nanoscale, can be grouped into two types, i...
May 17, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28549690/albumin-binding-domain-from-streptococcus-zooepidemicus-protein-zag-as-a-novel-strategy-to-improve-the-half-life-of-therapeutic-proteins
#8
Cátia Cantante, Sara Lourenço, Maurício Morais, João Leandro, Lurdes Gano, Nuno Silva, Paula Leandro, Mónica Serrano, Adriano O Henriques, Ana Andre, Catarina Cunha-Santos, Carlos Fontes, João D G Correia, Frederico Aires-da-Silva, Joao Goncalves
Recombinant antibody fragments belong to the promising class of biopharmaceuticals with high potential for future therapeutic applications. However, due to their small size they are rapidly cleared from circulation. Binding to serum proteins can be an effective approach to improve pharmacokinetic properties of short half-life molecules. Herein, we have investigated the Zag albumin-binding domain (ABD) derived from Streptococcus zooepidemicus as a novel strategy to improve the pharmacokinetic properties of therapeutic molecules...
May 24, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28520181/encapsulation-and-polymerization-of-white-phosphorus-inside-single-wall-carbon-nanotubes
#9
Martin Hart, Edward R White, Ji Chen, Catriona M McGilvery, Chris J Pickard, Angelos Michaelides, Andrea Sella, Milo S P Shaffer, Christoph G Salzmann
Elemental phosphorus displays an impressive number of allotropes with highly diverse chemical and physical properties. White phosphorus has now been filled into single-wall carbon nanotubes (SWCNTs) from the liquid and thereby stabilized against the highly exothermic reaction with atmospheric oxygen. The encapsulated tetraphosphorus molecules were visualized with transmission electron microscopy, but found to convert readily into chain structures inside the SWCNT "nanoreactors". The energies of the possible chain structures were determined computationally, highlighting a delicate balance between the extent of polymerization and the SWCNT diameter...
May 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28474608/compressive-strain-induced-enhancement-in-thermoelectric-power-factor-in-monolayer-mos2-nanosheet
#10
Dimple, Nityasagar Jena, Abir De Sarkar
Strain and temperature induced tunability in the thermoelectric properties in monolayer MoS2 (ML-MoS2) has been demonstrated using density functional theory coupled to semi-classical Boltzmann transport theory. Compressive strain, in general and uniaxial compressive strain (along the zig-zag direction), in particular, is found to be most effective in enhancing the thermoelectric power factor, owing to the higher electronic mobility and its sensitivity to lattice compression along this direction. Variation in the Seebeck coefficient and electronic band gap with strain is found to follow the Goldsmid-Sharp relation...
June 7, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28441236/the-new-mirus-system-for-short-term-sedation-in-postsurgical-icu-patients
#11
Stefano Romagnoli, Cosimo Chelazzi, Gianluca Villa, Giovanni Zagli, Francesco Benvenuti, Paola Mancinelli, Giulio Arcangeli, Stefano Dugheri, Alessandro Bonari, Lorenzo Tofani, Andrea Belardinelli, A Raffaele De Gaudio
OBJECTIVES: To evaluate the feasibility and safety of the MIRUS system (Pall International, Sarl, Fribourg, Switzerland) for sedation with sevoflurane for postsurgical ICU patients and to evaluate atmospheric pollution during sedation. DESIGN: Prospective interventional study. SETTING: Surgical ICU. February 2016 to December 2016. PATIENTS: Postsurgical patients requiring ICU admission, mechanical ventilation, and sedation...
April 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28440767/zinc-alpha-2-glycoprotein-is-overproduced-in-cushing-s-syndrome
#12
Xavier Escoté, Gloria B Aranda, Mireia Mora, Gregori Casals, Joaquim Enseñat, Oscar Vidal, Yaiza Esteban, Irene Halperin, Felicia A Hanzu
INTRODUCTION: Cushing syndrome (CS), an endogenous hypercortisolemic condition with increased cardiometabolic morbidity, leads to development of abdominal obesity, insulin resistance, diabetes and proatherogenic dyslipidemia. Zinc alpha-2 glycoprotein (ZAG) is a recently characterized lipolytic adipokine implicated in regulation of adipose tissue metabolism and fat distribution. In vitro and animal studies suggest that glucocorticoids interact with ZAG secretion and action. To assess the relationship between ZAG and glucocorticoids in a human model of hypercortisolism, circulating ZAG levels were tested in patients with CS and its counterpart controls...
January 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/28425473/2d-dige-as-a-strategy-to-identify-serum-biomarkers-in-mexican-patients-with-type-2-diabetes-with-different-body-mass-index
#13
Erik E Gómez-Cardona, Eric E Hernández-Domínguez, Aída J Velarde-Salcedo, Alberto-Barrera- Pacheco, Agustín Diaz-Gois, Antonio De León-Rodríguez, Ana P Barba de la Rosa
Obesity and type 2 diabetes(T2D) are the most prevalent and serious metabolic diseases affecting people worldwide. However racial and ethnic disparities seems to be a risk factor for their development. Mexico has been named as one of the largest populations with the highest prevalence of diabetes and obesity. The aim of this study was to identify novel T2D-associated proteins in Mexican patients. Blood samples were collected from 62 Mexican patients with T2D and they were grouped according to their body mass index(BMI)...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28370109/studies-on-effect-of-temperature-and-time-on-textural-and-rheological-properties-of-starch-isolated-from-traditional-rice-cultivars-of-kashmir-india
#14
Farhan M Bhat, Charanjit S Riar
In the present study, the effect of storage temperature and time on the textural and rheological properties of starch gels from seven different rice cultivars having higher amylose content than the hybrid rice varieties were evaluated. Water solubility and swelling power increased with every 10C increase in temperature due to granule swelling and solubilization of starch wherein the maximum solubility was found in starch of Koshkari rice cultivar (0.721 to 13.50) and swelling power in starch of Zag rice cultivar (3...
April 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28367566/anomalously-high-na-and-low-li-mobility-in-intercalated-na2ti6o13
#15
Chen Ling, Ruigang Zhang
We report an anomalous diffusion behavior in intercalated Na2Ti6O13. Using first-principles calculations, the direct migration of inserted Na(+) along the tunnel direction is predicted to have a barrier of 0.24-0.44 eV, while the migration of inserted Li(+) along the tunnel direction has a barrier of 0.86-1.15 eV. Although Li(+) can also diffuse along a zig-zag path in the tunnel, the barrier of 0.86-0.99 eV is still much higher than that for Na(+). Our results surprisingly lead to the conclusion that the diffusion of larger Na(+) is 4-8 orders of magnitude faster than Li(+) in the same host lattice, and explain the experimentally observed exceptional rate capability of Na2Ti6O13 as the Na-ion battery anode...
April 12, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28352283/serum-zag-levels-were-associated-with-egfr-mild-decrease-in-t2dm-patients-with-diabetic-nephropathy
#16
Lingling Xu, Weihong Yu, Meng Niu, Caixia Zheng, Bin Qu, Yan Li, Jing Wang, Ping Huang, O Wang, Fengying Gong
Objective. To investigate the changes of serum zinc-α2-glycoprotein (ZAG) in type 2 diabetes mellitus (T2DM) with eGFR mild decrease. Subjects and Methods. A total of 438 T2DM patients (61.3 ± 4.0 y) were recruited and the demographic, anthropometric, and biochemical parameters were all collected. Serum ZAG levels were determined by commercially available ELISA kits. Results. The proportion of T2DM patients with the high tertile ZAG levels was 11.9% higher in patients with mildly decreased estimated glomerular filtration rate (eGFR) (<90 mL/min/1...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28343061/automated-diabetic-macular-edema-dme-grading-system-using-dwt-dct-features-and-maculopathy-index
#17
U Rajendra Acharya, Muthu Rama Krishnan Mookiah, Joel E W Koh, Jen Hong Tan, Sulatha V Bhandary, A Krishna Rao, Yuki Hagiwara, Chua Kuang Chua, Augustinus Laude
The cause of diabetic macular edema (DME) is due to prolonged and uncontrolled diabetes mellitus (DM) which affects the vision of diabetic subjects. DME is graded based on the exudate location from the macula. It is clinically diagnosed using fundus images which is tedious and time-consuming. Regular eye screening and subsequent treatment may prevent the vision loss. Hence, in this work, a hybrid system based on Radon transform (RT), discrete wavelet transform (DWT) and discrete cosine transform (DCT) are proposed for an automated detection of DME...
March 19, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28317986/experimental-and-theoretical-evidence-for-the-ferromagnetic-edge-in-wse2-nanosheets
#18
Lei Tao, Fanchen Meng, Shudong Zhao, Yongli Song, Jianxin Yu, Xianjie Wang, Zhiguo Liu, Yi Wang, Bingsheng Li, Yang Wang, Yu Sui
Bulk TMDCs are diamagnetic materials; however, two-dimensional TMDCs exhibit spin polarized edge states, which results in a coupling between the unsaturated transition metal and chalcogenide atoms at the edges. The magnetism in two-dimensional TMDCs broadens their applications in spintronic and multi-functional devices. Herein, by combining macro/micro-magnetic experimental measurements and density functional theory (DFT) calculations, we demonstrate that among five possible edge-terminated WSe2 nanosheets only two types have a magnetic ground state, corresponding to the 100% Se edge terminated and 50% Se edge terminated nanosheets, respectively...
March 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28317202/cooperative-magnetism-in-crystalline-n-aryl-substituted-verdazyl-radicals-first-principles-predictions-and-experimental-results
#19
Steffen Eusterwiemann, Thomas Dresselhaus, Carsten Doerenkamp, Oliver Janka, Oliver Niehaus, Anja Massolle, Constantin G Daniliuc, Hellmut Eckert, Rainer Pöttgen, Johannes Neugebauer, Armido Studer
We report on a series of eight diaryl-6-oxo-verdazyl radicals containing a tert-butyl group at the C(3) position with regard to their crystal structure and magnetic properties by means of magnetic susceptibility measurements in combination with quantum chemical calculations using a first-principles bottom-up approach. The latter method allows for a qualitative prediction and detailed analysis of the correlation between the solid-state architecture and magnetic properties. Although the perturbation in the molecular structure by varying the substituent on the N-aryl ring may appear small, the effects upon the structural parameters controlling intermolecular magnetic coupling interactions are strong, resulting in a wide spectrum of cooperative magnetic behavior...
May 2, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28278439/a-case-of-single-incision-laparoscopic-surgery-for-a-bleeding-meckel-s-diverticulum-diagnosed-pre-operatively-by-double-balloon-endoscopy
#20
Toshio Shiraishi, Tetsuro Tominaga, Takashi Nonaka, Kouki Wakata, Masaki Kunizaki, Shuichi Tobinaga, Yorihisa Sumida, Shigekazu Hidaka, Naoe Kinoshita, Terumitsu Sawai, Takeshi Nagayasu
INTRODUCTION:  Meckel's diverticulum (MD) is a congenital true diverticulum that is residual yolk duct tissue, and some cases with complications require surgery. It has been reported that laparoscopic surgery is effective for patients with an MD. PRESENTATION OF CASE: A 79-year-old man with melena visited our hospital. Upper gastrointestinal series and colonoscopy showed no bleeding lesion. Double-balloon endoscopy was then performed to examine the small intestine...
February 22, 2017: International Journal of Surgery Case Reports
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