keyword
MENU ▼
Read by QxMD icon Read
search

neural mobilization

keyword
https://www.readbyqxmd.com/read/29775810/a-validated-uplc-ms-ms-method-for-the-quantitation-of-an-unstable-peptide-monocyte-locomotion-inhibitory-factor-mlif-in-human-plasma-and-its-application-to-a-pharmacokinetic-study
#1
Xuemei Liu, Pei Hu, Yongsheng Wang, Xizhu Wang, Jinghua Huang, Jin Li, Cheng Li, Hongyun Wang, Ji Jiang
Monocyte locomotion inhibitory factor (MLIF, Met-Gln-Cys-Asn-Ser), a pentapeptide with anti-inflammatory activity, was developed for neural protection in acute ischemic stroke. Determination of MLIF in human plasma samples is of great importance for pharmacokinetic evaluation in clinical studies. A reliable and sensitive method based on ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) was established for the measurement of MLIF in human plasma. Instability of peptide in matrix was the primary challenge in method development, which was properly resolved by addition of acidification reagents like sulfuric acid...
April 10, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29772518/brain-state-before-a-memory-probe-and-associative-retrieval-in-older-adults
#2
Jiangyi Xia, Giulia Galli, Leun J Otten
Older individuals' difficulty in remembering events from a particular time and place may be explained by changes in retrieval-related control processes. We investigated how aging affects neural activity leading up to a retrieval probe and how such activity relates to later performance. Electrical brain activity was recorded while healthy younger and older humans memorized visual word pairs consisting of an object word (e.g., doll) preceded by a location word (e.g., garden). Only object words were presented during the memory test, the task being to decide whether an object had been presented earlier and, if so, what location had been paired with it...
April 12, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29765462/development-of-a-new-intelligent-joystick-for-people-with-reduced-mobility
#3
Makrem Mrabet, Yassine Rabhi, Farhat Fnaiech
Despite the diversity of electric wheelchairs, many people with physical limitations and seniors have difficulty using their standard joystick. As a result, they cannot meet their needs or ensure safe travel. Recent assistive technologies can help to give them autonomy and independence. This work deals with the real-time implementation of an artificial intelligence device to overcome these problems. Following a review of the literature from previous work, we present the methodology and process for implementing our intelligent control system on an electric wheelchair...
2018: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/29758979/developmental-screening-tool-accuracy-and-feasibility-of-non-invasive-anaemia-estimation
#4
Raja Muthalagu, Vijayan Thulasi Bai, Doreen Gracias, Sheila John
Anaemia is predicted as one of the serious communal health issue in the world. The deficiency exists most common among children and women. A substantial issue prevails in providing quality healthcare services to rural communities, which remains a challenge to health service providers throughout the world. Traditionally physician and health workers recognized anaemia from certain clinical findings, such as pallor of the conjunctivae, nail beds, lips, tongue, and oral mucosa. Confirmation of anaemic condition through physical examination of Dorsum of a tongue or lower bulbar conjunctiva is a subjective analysis...
April 30, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29754802/intracellular-calcium-mobilization-is-required-for-sonic-hedgehog-signaling
#5
Dana Klatt Shaw, Derrick Gunther, Michael J Jurynec, Alexis A Chagovetz, Erin Ritchie, David Jonah Grunwald
Graded Shh signaling across fields of precursor cells coordinates patterns of gene expression, differentiation, and morphogenetic behavior as precursors form complex structures, such as the nervous system, the limbs, and craniofacial skeleton. Here we discover that intracellular calcium mobilization, a process tightly controlled and readily modulated, regulates the level of Shh-dependent gene expression in responding cells and affects the development of all Shh-dependent cell types in the zebrafish embryo. Reduced expression or modified activity of ryanodine receptor (RyR) intracellular calcium release channels shifted the allocation of Shh-dependent cell fates in the somitic muscle and neural tube...
May 8, 2018: Developmental Cell
https://www.readbyqxmd.com/read/29749639/the-homeodomain-transcription-factor-prox1-is-a-direct-target-of-soxc-proteins-during-developmental-vertebrate-neurogenesis
#6
Anne Jacob, Hannah M Wüst, Johannes M Thalhammer, Franziska Fröb, Melanie Küspert, Simone Reiprich, Elli-Anna Balta, D Chichung Lie, Michael Wegner, Elisabeth Sock
The high-mobility-group-domain containing SoxC transcription factors Sox4 and Sox11 are expressed and required in the vertebrate central nervous system in neuronal precursors and neuroblasts. To identify genes that are widely regulated by SoxC proteins during vertebrate neurogenesis we generated expression profiles from developing mouse brain and chicken neural tube with reduced SoxC expression and found the transcription factor Prox1 strongly downregulated under both conditions. This led us to hypothesize that Prox1 expression depends on SoxC proteins in the developing central nervous system of mouse and chicken...
May 11, 2018: Journal of Neurochemistry
https://www.readbyqxmd.com/read/29749381/effect-of-bmi1-over-expression-on-gene-expression-in-adult-and-embryonic-murine-neural-stem-cells
#7
Mythily Ganapathi, Nathan C Boles, Carol Charniga, Steven Lotz, Melissa Campbell, Sally Temple, Randall H Morse
The ability of isolated neural stem cells (NSCs) to proliferate as neurospheres is indicative of their competence as stem cells, and depends critically on the polycomb group (PcG) member Bmi1: knockdown of Bmi1 results in defective proliferation and self-renewal of isolated NSCs, whereas overexpression of Bmi1 enhances these properties. Here we report genome-wide changes in gene expression in embryonic and adult NSCs (eNSCs and aNSCs) caused by overexpression of Bmi1. We find that genes whose expression is altered by perturbations in Bmi1 levels in NSCs are mostly distinct from those affected in other multipotent stem/progenitor cells, such as those from liver and lung, aside from a small core of common targets that is enriched for genes associated with cell migration and mobility...
May 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29748521/self-tuning-method-for-increased-obstacle-detection-reliability-based-on-internet-of-things-lidar-sensor-models
#8
Fernando Castaño, Gerardo Beruvides, Alberto Villalonga, Rodolfo E Haber
On-chip LiDAR sensors for vehicle collision avoidance are a rapidly expanding area of research and development. The assessment of reliable obstacle detection using data collected by LiDAR sensors has become a key issue that the scientific community is actively exploring. The design of a self-tuning methodology and its implementation are presented in this paper, to maximize the reliability of LiDAR sensors network for obstacle detection in the 'Internet of Things' (IoT) mobility scenarios. The Webots Automobile 3D simulation tool for emulating sensor interaction in complex driving environments is selected in order to achieve that objective...
May 10, 2018: Sensors
https://www.readbyqxmd.com/read/29748495/irisdensenet-robust-iris-segmentation-using-densely-connected-fully-convolutional-networks-in-the-images-by-visible-light-and-near-infrared-light-camera-sensors
#9
Muhammad Arsalan, Rizwan Ali Naqvi, Dong Seop Kim, Phong Ha Nguyen, Muhammad Owais, Kang Ryoung Park
The recent advancements in computer vision have opened new horizons for deploying biometric recognition algorithms in mobile and handheld devices. Similarly, iris recognition is now much needed in unconstraint scenarios with accuracy. These environments make the acquired iris image exhibit occlusion, low resolution, blur, unusual glint, ghost effect, and off-angles. The prevailing segmentation algorithms cannot cope with these constraints. In addition, owing to the unavailability of near-infrared (NIR) light, iris recognition in visible light environment makes the iris segmentation challenging with the noise of visible light...
May 10, 2018: Sensors
https://www.readbyqxmd.com/read/29742719/cauda-equina-syndrome-following-an-uneventful-spinal-anesthesia-in-a-patient-undergoing-drainage-of-the-bartholin-abscess-a-case-report
#10
Waldo Merino-Urrutia, Milca Villagrán-Schmidt, Priscilla Ulloa-Vásquez, Rubén Carrasco-Moyano, Alberto Uribe, Nicoleta Stoicea, Sergio D Bergese
RATIONALE: Neuraxial anesthesia is a commonly used type of regional anesthesia. Cauda equina syndrome is an unusual and severe complication of neuraxial anesthesia, and is caused by damage to the sacral roots of the neural canal. We present a case of cauda equina syndrome following spinal anesthesia in a patient who underwent Bartholin abscess drainage. PATIENT CONCERNS: A 23-year old female scheduled to undergo surgical drainage of Bartholin abscess. Spinal anesthesia was performed with bupivacaine and fentanyl...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29741265/-walking-through-the-sensory-cognitive-and-temporal-degradations-of-healthy-aging
#11
REVIEW
Nadia Paraskevoudi, Fuat Balcı, Argiro Vatakis
As we age, there is a wide range of changes in motor, sensory, cognitive, and temporal processing due to alterations in the functioning of the central nervous and musculoskeletal systems. Specifically, aging is associated with degradations in gait; altered processing of the individual sensory systems; modifications in executive control, memory, and attention; and changes in temporal processing. These age-related alterations are often inter-related and have been suggested to result from shared neural substrates...
May 9, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29732993/endothelial-progenitor-cells-as-molecular-targets-in-vascular-senescence-and-repair
#12
Divya Rana, Saurabh Sharma
Endothelial progenitor cells are circulating blood cells derived from various sources like bone marrow, spleen, umbilical cord, liver, kidney and other sources that play a vital role in the regeneration of endothelial lining of blood vessels and wound repair. There are two types of EPCs, early EPCs and late EPCs. EPCs are believed to originate from hematopoietic stem cells and mesenchymal stem cells. The mobilization of progenitor cells from bone marrow to the peripheral circulation is highly regulated under both normal physiological conditions and stress...
May 1, 2018: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29720239/a-subset-of-mobilized-human-hematopoietic-stem-cells-express-germ-layer-lineage-genes-which-can-be-modulated-by-culture-conditions
#13
Tapas Makar, Vamshi K Nimmagadda, Poornachander R Guda, Brian Hampton, Weiliang Huang, Maureen A Kane, Paul S Fishman, Bernard Pessac, Christopher T Bever, David Trisler
BACKGROUND: Adult bone marrow contains stem cells that replenish the myeloid and lymphoid lineages. A subset of human and mouse CD34+ bone marrow stem cells can be propagated in culture to autonomously express embryonic stem cell genes and embryonic germ layer lineage genes. The current study was undertaken to determine whether these CD34+ stem cells could be obtained from human blood, whether gene expression could be modulated by culture conditions and whether the cells produce insulin...
May 2, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29688217/a-mobile-brain-body-imaging-dataset-recorded-during-treadmill-walking-with-a-brain-computer-interface
#14
Yongtian He, Trieu Phat Luu, Kevin Nathan, Sho Nakagome, Jose L Contreras-Vidal
We present a mobile brain-body imaging (MoBI) dataset acquired during treadmill walking in a brain-computer interface (BCI) task. The data were collected from eight healthy subjects, each having three identical trials. Each trial consisted of three conditions: standing, treadmill walking, and treadmill walking with a closed-loop BCI. During the BCI condition, subjects used their brain activity to control a virtual avatar on a screen to walk in real-time. Robust procedures were designed to record lower limb joint angles (bilateral hip, knee, and ankle) using goniometers synchronized with 60-channel scalp electroencephalography (EEG)...
April 24, 2018: Scientific Data
https://www.readbyqxmd.com/read/29684712/high-salt-intake-enhances-swim-stress-induced-pvn-vasopressin-cell-activation-and-active-stress-coping
#15
N C Mitchell, T L Gilman, L C Daws, G M Toney
PURPOSE: Stress contributes to many psychiatric disorders; however, responsivity to stressors can vary depending on previous or current stress exposure. Relatively innocuous heterotypic (differing in type) stressors can summate to result in exaggerated neuronal and behavioral responses. Here we investigated the ability of prior high dietary sodium chloride (salt) intake, a dehydrating osmotic stressor, to enhance neuronal and behavioral responses of mice to an acute psychogenic swim stress (SS)...
April 6, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29673171/litenet-lightweight-neural-network-for-detecting-arrhythmias-at-resource-constrained-mobile-devices
#16
Ziyang He, Xiaoqing Zhang, Yangjie Cao, Zhi Liu, Bo Zhang, Xiaoyan Wang
By running applications and services closer to the user, edge processing provides many advantages, such as short response time and reduced network traffic. Deep-learning based algorithms provide significantly better performances than traditional algorithms in many fields but demand more resources, such as higher computational power and more memory. Hence, designing deep learning algorithms that are more suitable for resource-constrained mobile devices is vital. In this paper, we build a lightweight neural network, termed LiteNet which uses a deep learning algorithm design to diagnose arrhythmias, as an example to show how we design deep learning schemes for resource-constrained mobile devices...
April 17, 2018: Sensors
https://www.readbyqxmd.com/read/29670573/gait-asymmetry-in-people-with-parkinson-s-disease-is-linked-to-reduced-integrity-of-callosal-sensorimotor-regions
#17
Brett W Fling, Carolin Curtze, Fay B Horak
Background: Individuals with Parkinson's disease (PD) often manifest significant temporal and spatial asymmetries of the lower extremities during gait, which significantly contribute to mobility impairments. While the neural mechanisms underlying mobility asymmetries within this population remain poorly understood, recent evidence points to altered microstructural integrity of white matter fiber tracts within the corpus callosum as potentially playing a substantial role. Objectives: The purpose of this study was to quantify spatial and temporal gait asymmetries as well as transcallosal microstructural integrity of white matter fiber tracts connecting the primary and secondary sensorimotor cortices in people with PD and age-matched control participants...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29670503/mobile-phone-chips-reduce-increases-in-eeg-brain-activity-induced-by-mobile-phone-emitted-electromagnetic-fields
#18
Diana Henz, Wolfgang I Schöllhorn, Burkhard Poeggeler
Recent neurophysiological studies indicate that exposure to electromagnetic fields (EMFs) generated by mobile phone radiation can exert effects on brain activity. One technical solution to reduce effects of EMFs in mobile phone use is provided in mobile phone chips that are applied to mobile phones or attached to their surfaces. To date, there are no systematical studies on the effects of mobile phone chip application on brain activity and the underlying neural mechanisms. The present study investigated whether mobile phone chips that are applied to mobile phones reduce effects of EMFs emitted by mobile phone radiation on electroencephalographic (EEG) brain activity in a laboratory study...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29650593/human-neural-stem-cell-extracellular-vesicles-improve-recovery-in-a-porcine-model-of-ischemic-stroke
#19
Robin L Webb, Erin E Kaiser, Brian J Jurgielewicz, Samantha Spellicy, Shelley L Scoville, Tyler A Thompson, Raymond L Swetenburg, David C Hess, Franklin D West, Steven L Stice
BACKGROUND AND PURPOSE: Recent work from our group suggests that human neural stem cell-derived extracellular vesicle (NSC EV) treatment improves both tissue and sensorimotor function in a preclinical thromboembolic mouse model of stroke. In this study, NSC EVs were evaluated in a pig ischemic stroke model, where clinically relevant end points were used to assess recovery in a more translational large animal model. METHODS: Ischemic stroke was induced by permanent middle cerebral artery occlusion (MCAO), and either NSC EV or PBS treatment was administered intravenously at 2, 14, and 24 hours post-MCAO...
April 12, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29629431/rstensorflow-gpu-enabled-tensorflow-for-deep-learning-on-commodity-android-devices
#20
Moustafa Alzantot, Yingnan Wang, Zhengshuang Ren, Mani B Srivastava
Mobile devices have become an essential part of our daily lives. By virtue of both their increasing computing power and the recent progress made in AI, mobile devices evolved to act as intelligent assistants in many tasks rather than a mere way of making phone calls. However, popular and commonly used tools and frameworks for machine intelligence are still lacking the ability to make proper use of the available heterogeneous computing resources on mobile devices. In this paper, we study the benefits of utilizing the heterogeneous (CPU and GPU) computing resources available on commodity android devices while running deep learning models...
June 2017: MobiSys ...: the ... International Conference on Mobile Systems, Applications and Services. International Conference on Mobile Systems, Applications, and Services
keyword
keyword
75761
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"