Read by QxMD icon Read


Michael Mazzeffi, Srikar Jonna, Natalia Blanco, Orestes Mavrothalassitis, Obi Odekwu, Magali Fontaine, Peter Rock, Kenichi Tanaka, Kerri Thom
BACKGROUND: Kidney transplant patients are frequently anemic and at risk for red blood cell (RBC) transfusion. Previous studies suggest that pre-transplant RBC transfusion may improve kidney transplant outcomes; however, RBC transfusion is also associated with infection. The purpose of our study was to characterize the relationships between intraoperative RBC transfusion, delayed graft function (DGF), postoperative surgical site infection (SSI), and sepsis. METHODS: Analysis was performed on a historical cohort of adult kidney transplant patients from a single medical center during a two-year period...
March 20, 2018: Journal of Anesthesia
Kathrin Thöne, Anja Rudolph, Nadia Obi, Jenny Chang-Claude, Dieter Flesch-Janys
PURPOSE: Recent cohort studies demonstrated better overall survival (OS) or breast cancer-specific survival (BCS) for breast-conserving therapy (BCT) followed by radiation (RT) compared to mastectomy alone (MT). This is the first observational study in which adjustments for a comprehensive set of prognostic factors, adjuvant therapies, mode of detection, and comorbidities were possible to investigate OS, BCS, as well as recurrence risk of patients undergoing BCT + RT, MT + RT, or MT...
March 19, 2018: Breast Cancer Research and Treatment
Masashi Sakuma, Takahisa Nasuno, Shichiro Abe, Syotaro Obi, Shigeru Toyoda, Isao Taguchi, Ryoichi Sohma, Ken-Ichi Inoue, Setsu Nishino, Koichi Node, Guiherme Attizzani, Hiram Bezerra, Marco Costa, Daniel Simon, Teruo Inoue
Background: Bone marrow-derived progenitor cells likely contribute to both endothelial- and smooth muscle cell-dependent healing responses in stent-injured vessel sites. This study aimed to assess mobilization of progenitor cells and vessel healing after zotarolimus-eluting (ZES) and everolimus-eluting (EES) stents. Methods and results: In 63 patients undergoing coronary stent implantation, we measured circulating CD34 + CD133 + CD45low cells and serum levels of biomarkers relevant to stem cell mobilization...
March 2018: IJC Heart & Vasculature
Vijay Kodadhala, Jennifer Obi, Priscilla Wessly, Alem Mehari, R F Gillum
BACKGROUND: Asthma mortality based on the underlying cause of death (UCOD) underestimates disease burden. OBJECTIVE: Therefore, in this study, asthma mortality in the US 1999-2015 was analyzed, as well as the pattern of reporting of asthma and its co-morbidities in death certificates, using multiple-cause of death (MCOD) records. METHODS: All 156,517 death certificates with any mention of asthma were analyzed for 1999-2015. Asthma was defined by ICD-10 code J45 based either on the UCOD or MCOD...
March 13, 2018: Annals of Allergy, Asthma & Immunology
K Obi Reddy, C Uma Maheswari, M S Dhlamini, B M Mothudi, V P Kommula, Jinming Zhang, Jun Zhang, A Varada Rajulu
With increasing awareness of protecting the environment, the demand for renewable and environmental materials is increasing. In this work, the cellulose single fibers (CSFs) were extracted from the African native Napier grass fibers (NGFs) by chemical process. NGFs and CSFs were characterized for their chemical composition, structure, morphology, crystallinity and thermal properties using, chemical analysis, FTIR, 13C CP/MAS NMR, SEM, XRD and TGA techniques. The resulted CSFs had higher α-cellulose content, crystallinity and thermal stability than the pristine NGFs...
May 15, 2018: Carbohydrate Polymers
Wei Ling Lau, Yoshitsugu Obi, Kamyar Kalantar-Zadeh
Secondary hyperparathyroidism develops in CKD due to a combination of vitamin D deficiency, hypocalcemia, and hyperphosphatemia, and it exists in nearly all patients at the time of dialysis initiation. There is insufficient data on whether to prefer vitamin D analogs compared with calcimimetics, but the available evidence suggests advantages with combination therapy. Calcium derangements, patient adherence, side effects, and cost limit the use of these agents. When parathyroid hormone level persists >800 pg/ml for >6 months, despite exhaustive medical interventions, monoclonal proliferation with nodular hyperplasia is likely present along with decreased expression of vitamin D and calcium-sensing receptors...
March 9, 2018: Clinical Journal of the American Society of Nephrology: CJASN
I E Obi, A N Charles-Okoli, C C Agunwa, B I Omotowo, A C Ndu, O R Agwu-Umahi
Context: Learning in the medical school of the study university is still by the traditional face-to-face approach with minimal e-communication. Aim: This paper assesses student's perspectives of E-learning readiness, its predictors and presents a model for assessing them. Settings and Design: A descriptive cross-sectional study of medical students. Subjects and Methods: By proportional quota sampling 284 students responded to a semi-structured self-administered questionnaire adapted from literature...
March 2018: Nigerian Journal of Clinical Practice
Sheryl Tulin-Silver, Chrystal Obi, Nishita Kothary, Matthew Lungren
PURPOSE: The aim of the study was to compare safety and efficacy of transjugular liver biopsy (TJLB) and percutaneous liver biopsy (PLB) with tract embolization in pediatric patients with liver disease. MATERIALS AND METHODS: TJLB and PLB between December 2009 and October 2015 were retrospectively reviewed. Primary endpoints were adequate sampling and complication rate. Patient age, weight, coagulation factors, ascites, blood transfusions, adequacy of biopsy sample, number of biopsy samples, and complications were compared...
March 5, 2018: Journal of Pediatric Gastroenterology and Nutrition
Mima Uegomori, Yuko Haraguchi, Takeshi Obi, Kozo Takase
We analyzed the gizzards, and grits retained in the gizzards of 41 cranes that migrated to the Izumi Plain during the winter of 2015/2016 and died there, either due to accident or disease. These included 31 Hooded Cranes (Grus monacha) and 10 White-naped Cranes (G. vipio). We determined body weight, gizzard weight, total grit weight and number per gizzard, and size, shape, and surface roundness of the grits. Average gizzard weights were 92.4 g for Hooded Cranes and 97.1 g for White-naped Cranes, and gizzard weight positively correlated with body weight in both species...
March 5, 2018: Journal of Veterinary Medical Science
Tayibe Bal, Yusuf Onlen
BACKGROUND AND STUDY AIMS: Occult hepatitis B infection (OBI) is known to be mostly prevalent in chronic hepatitis C (CHC) patients and OBI reactivation might be life-threatening in patients undergoing interferon (IFN)-free direct acting antiviral (DAA) therapy. As previous studies have revealed a relationship between OBI and non-response to IFN-based antiviral therapy, the aim of the current study was to determine if there was a higher prevalence of OBI in IFN non-responders than responders...
March 1, 2018: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
Margaret Smith, Glenn Wakam, Thomas Wakefield, Andrea Obi
Anticoagulation pharmacy has been dramatically altered with US Food and Drug Administration (FDA) approval of 5 direct oral anticoagulants, 1 novel reversal agent and, a second designated for fast-track approval. Trial data surrounding current trends in anticoagulant choice for VTE, reversal, and bridging are constantly redefining practice. Extended therapy for unprovoked VTE has expanded to include low-dose direct oral anticoagulants, aspirin, and the use of the HERDOO2 system to identify women who can stop anticoagulant therapy without increased risk of recurrent VTE...
April 2018: Surgical Clinics of North America
Andrew Kimball, Matthew Schaller, Amrita Joshi, Frank Davis, Aaron denDekker, Anna Boniakowski, Jennifer Bermick, Andrea Obi, Bethany Moore, Peter K Henke, Steve L Kunkel, Katherine A Gallagher
OBJECTIVE: Wound monocyte-derived macrophage plasticity controls the initiation and resolution of inflammation that is critical for proper healing, however, in diabetes mellitus, the resolution of inflammation fails to occur. In diabetic wounds, the kinetics of blood monocyte recruitment and the mechanisms that control in vivo monocyte/macrophage differentiation remain unknown. APPROACH AND RESULTS: Here, we characterized the kinetics and function of Ly6CHi [Lin- (CD3- CD19- NK1...
March 1, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
Rajiv Saran, Bruce Robinson, Kevin C Abbott, Lawrence Y C Agodoa, Nicole Bhave, Jennifer Bragg-Gresham, Rajesh Balkrishnan, Xue Dietrich, Ashley Eckard, Paul W Eggers, Abduzhappar Gaipov, Daniel Gillen, Debbie Gipson, Susan M Hailpern, Yoshio N Hall, Yun Han, Kevin He, William Herman, Michael Heung, Richard A Hirth, David Hutton, Steven J Jacobsen, Yan Jin, Kamyar Kalantar-Zadeh, Alissa Kapke, Csaba P Kovesdy, Danielle Lavallee, Janet Leslie, Keith McCullough, Zubin Modi, Miklos Z Molnar, Maria Montez-Rath, Hamid Moradi, Hal Morgenstern, Purna Mukhopadhyay, Brahmajee Nallamothu, Danh V Nguyen, Keith C Norris, Ann M O'Hare, Yoshitsugu Obi, Christina Park, Jeffrey Pearson, Ronald Pisoni, Praveen K Potukuchi, Panduranga Rao, Kaitlyn Repeck, Connie M Rhee, Jillian Schrager, Douglas E Schaubel, David T Selewski, Sally F Shaw, Jiaxiao M Shi, Monica Shieu, John J Sim, Melissa Soohoo, Diane Steffick, Elani Streja, Keiichi Sumida, Manjula K Tamura, Anca Tilea, Lan Tong, Dongyu Wang, Mia Wang, Kenneth J Woodside, Xin Xin, Maggie Yin, Amy S You, Hui Zhou, Vahakn Shahinian
No abstract text is available yet for this article.
March 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Zahra Tajik, Farah Bokharaei-Salim, Saied Ghorbani, Hossein Keyvani, Maryam Esghaei, Seyed Hamidreza Monavari, Angila Ataei-Pirkooh, Saba Garshasbi, Tahereh Donyavi, Atousa Fakhim
The presence of hepatitis B virus (HBV) DNA in the absence of traceable hepatitis B surface antigen (HBsAg) in the plasma specimen of patients is defined as occult HBV infection (OBI). This study aimed to detect HBV-DNA in the plasma and peripheral blood mononuclear cells (PBMCs) of Iranian HBsAg negative patients with human immunodeficiency virus (HIV) infection. This cross-sectional study was conducted on 172 patients with HIV infection from September 2015 to August 2017. The patients were tested for serological parameters (HBsAg, HBcAb, HBeAg and HBeAb) against HBV infection...
February 23, 2018: Archives of Virology
J Obis, M Satue, R Alarcia, L E Pablo, E Garcia-Martin
Parkinson's disease (PD) is a neurodegenerative process that affects 7.5 million people around the world. Since 2004, several studies have demonstrated changes in various retinal layers in PD using optical coherence tomography (OCT). However, there are some discrepancies in the results of those studies. Some of them have correlated retinal thickness with the severity or duration of the disease, demonstrating that OCT measurements may be an innocuous and easy biomarker for PD progression. Other studies have demonstrated visual dysfunctions since early phases of the disease...
February 14, 2018: Archivos de la Sociedad Española de Oftalmología
Carla de Castro Sant' Anna, Marcella Kelly Costa de Almeida, Patrícia Ferreira, Roseane Gomes de Oliveira, Anna Rafaella Ferreira Baraúna, Evonnildo Costa Gonçalvez, Andrea Marinho da Silva, Carolina de Souza Pereira, Luisa Carício Martins
In the present study, we evaluated the prevalence of occult hepatitis B (OBI) in a population from the Brazilian Amazon region, identify circulating genotypes and mutations in the S gene. 181 patients with negative serology for HBsAg and anti-HBs and positive serology for anti-HBc participated in the study. Detection of viral DNA, genotyping by sequencing and analysis of nucleotide sequences to detect possible mutations were performed. HBV DNA was detected in 14.36% of the patients. Genotyping revealed genotype A in 88...
February 15, 2018: Journal of Medical Virology
Naoko Obi, Tetsuya Fukuda, Noboru Nakayama, John Ervin, Yasuhiko Bando, Toshihide Nishimura, Satoru Nagatoishi, Kouhei Tsumoto, Takeshi Kawamura
RATIONALE: Drug discovery studies invariably require qualitative and quantitative analyses of target compounds at every stage of drug discovery. We have developed a system combining molecular interaction analysis and mass spectrometry (LC-MS) using the principle of nano pore optical interferometry (nPOI) called molecular interaction kinetics-mass spectrometry (MIK-MS). Since nPOI has high binding capacity, the bond-dissociated compound can be directly detected using LC-MS. In this study, we use carbonic anhydrase (CA) II as a ligand and apply six small compounds as analytes and report the affinity analysis using MIK-MS...
February 14, 2018: Rapid Communications in Mass Spectrometry: RCM
Mohammed Al Sheikh, Nick Simson, Obinna Obi-Njoku, Ahmed Qteishat
A previously healthy 61-year-old Caucasian woman presented to the emergency department after collapsing at home with associated abdominal pain radiating to her back. An urgent CT angiogram was requested to rule out a ruptured aortic aneurysm. This showed a large 21 cm fat-containing lesion arising from the mid-pole of the left kidney, with an adjacent 4 cm perirenal haematoma. An initial diagnosis of a ruptured angiomyolipoma was made. Her haemoglobin was 105 g/L, with a creatinine of 104 mmol/L and an eGFR of 47 mL/min...
February 8, 2018: BMJ Case Reports
Yuri Hatazawa, Yoshihiko Yano, Rina Okada, Toshihito Tanahashi, Hiroki Hayashi, Hirotaka Hirano, Akihiro Minami, Yuki Kawano, Motofumi Tanaka, Takumi Fukumoto, Yoshiki Murakami, Masaru Yoshida, Yoshitake Hayashi
Background: Hepatocellular carcinoma (HCC) can develop in patients who are negative for the hepatitis B surface antigen (HBsAg) in serum but positive for hepatitis B virus (HBV) DNA in the liver, referred to as occult HBV infection (OBI). Previous reports showed that HBV variants in OBI-related HCC are different from those in HBsAg-positive HCC. In the present study, HBV quasispecies based on the pre-S/S gene in OBI-related HCC patients were examined by high throughput sequencing and compared with those in HBsAg-positive HCC...
2018: Infectious Agents and Cancer
Mireille Conrad, Grégory Bolard, Marie Nowak, Berardino De Bari, Wendy Jeanneret-Sozzi, Jean Bourhis, Jean-François Germond, François Bochud, Raphaël Moeckli
PURPOSE: Image guided radiotherapy (IGRT) improves patient positioning for treatment delivery at the cost of an additional dose. This work aimed to calculate the effective dose (as an indicator of dose) for head & neck (H&N) and breast IGRT treatments by implementing dose calculation models to determine the dose distributions. METHODS: The kV dose-models were created for the IGRT systems of Elekta Synergy (XVI) and Varian Clinac (OBI) linear accelerators within Philips Pinnacle TPS...
February 6, 2018: Zeitschrift Für Medizinische Physik
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"