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https://www.readbyqxmd.com/read/28816548/dietary-supplementation-with-virgin-coconut-oil-improves-lipid-profile-and-hepatic-antioxidant-status-and-has-potential-benefits-on-cardiovascular-risk-indices-in-normal-rats
#1
Ademola C Famurewa, Chima A Ekeleme-Egedigwe, Sophia C Nwali, Ngozi N Agbo, Joy N Obi, Goodness C Ezechukwu
Research findings that suggest beneficial health effects of dietary supplementation with virgin coconut oil (VCO) are limited in the published literature. This study investigated the in vivo effects of a 5-week VCO-supplemented diet on lipid profile, hepatic antioxidant status, hepatorenal function, and cardiovascular risk indices in normal rats. Rats were randomly divided into 3 groups: 1 control and 2 treatment groups (10% and 15% VCO-supplemented diets) for 5 weeks. Serum and homogenate samples were used to analyze lipid profile, hepatorenal function markers, hepatic activities of antioxidant enzymes, and malondialdehyde level...
August 17, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28812910/orbital-cancer-a-second-cancer-in-exenterated-patients
#2
Ebube E Obi, David Saunders, Joyce Burns, Ragavan Sampath
No abstract text is available yet for this article.
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28804513/noncirrhotic-hepatocellular-carcinoma-etiology-and-occult-hepatitis-b-virus-infection-in-a-hepatitis-b-virus-endemic-area
#3
Chang Woo Shim, Joong-Won Park, So Hee Kim, Jin Sook Kim, Bo Hyun Kim, Sung Hoon Kim, Eun Kyung Hong
BACKGROUND: Although hepatocellular carcinoma (HCC) usually develops in cirrhotic livers, a minority of cases occur in noncirrhotic livers (NCLs). We investigated etiology, clinicopathological features, and occult hepatitis B virus (HBV) infection (OBI) in patients with NCL HCC in an HBV-endemic area. METHODS: A total of 710 patients who underwent resection or transplantation for HCC at the National Cancer Center (NCC), Korea, were enrolled. HCC and fibrosis stage were diagnosed pathologically...
July 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28769648/demersal-and-pelagic-species-of-fish-and-squid-from-the-patagonian-shelf
#4
Elena Beatríz Eder, María Rosa Marin, Mirtha Noemí Lewis
The dataset contains 2007 records of occurrence of 39 species of fish and 2 species of squid distributed on the Patagonian continental shelf and slope. This dataset describes a new and revised version of the original data published through OBIS with individual morphometrics. Specimens are representative of pelagic, demersal, demersal-pelagic, demersal-benthic and benthic habits and they were collected by commercial fishing vessels in autumn (May-June, 2001, 51 catches), winter (July-August, 2001, 38 catches) and summer (January-February, 2002, 112 catches)...
2017: ZooKeys
https://www.readbyqxmd.com/read/28760689/comprehensive-discovery-of-non-coding-rnas-in-acute-myeloid-leukemia-cell-transcriptomes
#5
Jin Zhang, Malachi Griffith, Christopher A Miller, Obi L Griffith, David H Spencer, Jason R Walker, Vincent Magrini, Sean D McGrath, Amy Ly, Nichole M Helton, Maria Trissal, Daniel C Link, Ha X Dang, David E Larson, Shashikant Kulkarni, Matthew G Cordes, Catrina C Fronick, Robert S Fulton, Jeffery M Klco, Elaine R Mardis, Timothy J Ley, Richard K Wilson, Christopher A Maher
To comprehensively detect diverse and novel RNA species, we compared deep small RNA and RNA sequencing (RNA-seq) methods applied to a primary acute myeloid leukemia (AML) sample. We were able to discover previously unannotated small RNAs using deep sequencing of a library method employing broader insert size selection. We analyzed the long non-coding RNA (lncRNA) landscape in AML by comparing deep sequencing from multiple RNA-seq library construction methods for the sample we studied, then integrating RNA-seq data from 179 AML cases...
July 28, 2017: Experimental Hematology
https://www.readbyqxmd.com/read/28760001/association-of-obesity-with-healthcare-utilization-and-costs-in-a-medicare-population
#6
Brandon T Suehs, Pravin Kamble, Joanna Huang, Mette Hammer, Jonathan Bouchard, Mary E Costantino, Andrew Renda
OBJECTIVES: To examine the association of obesity on healthcare resource utilization and costs in a Medicare population. METHODS: This study was a retrospective cohort study using Humana Medicare Advantage (MA) claims data. Body mass index (BMI) was assessed using ICD-9-CM status codes (V85 hierarchy) that have been validated in the data source to classify patients into BMI categories: Normal (N), Overweight (Ow), Obese class I (ObI), Obese class II (ObII), and Obese class III (ObIII)...
August 1, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28757526/morphologically-abnormal-beaks-observed-in-chickens-that-were-beak-trimmed-at-young-ages
#7
Yuki Yamauchi, Shu Yoshida, Hiroyuki Matsuyama, Takeshi Obi, Kozo Takase
A survey of beak morphological abnormalities was performed on 6,201 chickens (egg-laying hens and chickens for meat production belonging to 25 flocks) brought to a poultry processing plant. The observed abnormalities varied among flocks with occurrence rates ranging from 0.48 to 46.67%. The occurrence was high in flocks subjected to beak trimming and varied significantly according to chicken breed, with the highest rates of abnormalities in a certain chicken breed. The most widely observed abnormalities were: 1) uneven growth of the upper and lower mandibles, mostly with elongation of the lower mandible (accounting for 64...
July 31, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28753964/the-limpopo-non-metropolitan-drinking-water-supplier-response-to-a-diagnostic-tool-for-technical-compliance
#8
Avhashoni D Nefale, Ilunga Kamika, Chikwelu L Obi, Maggy Nb Momba
Water services providers should supply water that is fit for human consumption, taking into account multi-barrier approaches and technical aspects such as design aspects, operation monitoring, final water quality compliance monitoring, plant monitoring practices, maintenance, and risk management practices. Against this background, this study focused on applying the diagnostic tool for technical compliance as well as assessing the compliance of water treatment plants with management norms. Six plants in the Vhembe District Municipality were selected; the Vondo, Malamulele, Mutshedzi, and Mutale plants (conventional), and the Dzingahe and Tshedza package plants...
July 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28748890/prevalence-of-hepatitis-b-core-antibodies-with-negative-hepatitis-b-surface-antigen-in-dialysis-and-chronic-kidney-disease-patients
#9
Nauman Tarif, Muhammad Mohsin Riaz, Omer Sabir, Rizwan Akhter, Kashif Rafique, Nabiha Rizvi
Occult hepatitis B infection (OBI) is a potential cause of infection transmission in patients with chronic kidney disease (CKD) and dialysis-dependant patients. It is liable to be missed since the marker for OBI, hepatitis B core antibody (HBcAb), is not done routinely. We carried out a study to assess the prevalence of OBI in CKD Stage II-V or requiring renal replacement therapy. It was a cross-sectional study carried out at Fatima Memorial Hospital, Lahore, from May 2104 to May 2015. A total of 188 patients were included in this study, 124 were dialysis dependent and 64 had acute or CKD Stage II-V...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28747700/association-of-pre-operative-estimated-gfr-on-post-operative-pulmonary-complications-in-laparoscopic-surgeries
#10
Akihiro Shimomura, Yoshitsugu Obi, Reza Fazl Alizadeh, Shiri Li, Ninh T Nguyen, Michael J Stamos, Kamyar Kalantar-Zadeh, Hirohito Ichii
Despite a large body of evidence showing the pandemic of chronic kidney disease, the impact of pre-operative kidney function on the risk of post-operative pulmonary complications (PPCs) is not well known. We used multivariable logistic regression analyses with 3-level hierarchical adjustments to identify the association of pre-operative estimated glomerular filtration rate (eGFR) with PPCs in laparoscopic surgeries. Among 452,213 patients between 2005 and 2013 in the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) Database, a total of 3,727 patients (0...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28705716/occult-hepatitis-b-virus-infection-in-greek-patients-with-congenital-bleeding-disorders
#11
Agoritsa Varaklioti, Anna Kouramba, Panagiota Ioannidou, Olga Katsarou
Occult Hepatitis B Infection (OBI) is a form of chronic HBV infection characterized by low level HBV DNA, without detectable HBV surface antigen (HBsAg). OBI is frequently associated with the presence of anti-HBc and in some cases also with anti-HBs. Patients, who formerly received non-inactivated factor concentrates, can potentially be considered at high risk for OBI, especially since these patients usually are HIV or HCV co-infected. This study aimed to assess the prevalence of occult HBV infection in Greek patients with hereditary bleeding disorders...
July 10, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28704813/serum-ferritin-variations-and-mortality-in-incident-hemodialysis-patients
#12
Taehee Kim, Elani Streja, Melissa Soohoo, Connie M Rhee, Rieko Eriguchi, Tae Woo Kim, Tae Ik Chang, Yoshitsugu Obi, Csaba P Kovesdy, Kamyar Kalantar-Zadeh
BACKGROUND: Higher serum ferritin levels may be influenced by iron use and inflammation, and are associated with higher mortality in hemodialysis (HD) patients. We hypothesized that a major rise in serum ferritin is associated with a higher risk of mortality, irrespective of baseline serum ferritin in incident HD patients. METHODS: In a cohort of 93,979 incident HD patients between 2007 and 2011, we examined the association of change in serum ferritin from the baseline patient quarter (first 91 days from dialysis start) to the subsequent quarter with mortality...
July 14, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28704074/quantifying-the-relative-importance-to-patients-of-avoiding-symptoms-and-outcomes-of-heart-failure
#13
A Brett Hauber, Engels N Obi, Mark A Price, Diane Whalley, Chun-Lan Chang
OBJECTIVE: To evaluate heart failure (HF) patients' disease knowledge and preferences for avoiding different disease outcomes. METHODS: An online survey was administered to 400 individuals with a self-reported diagnosis of HF to elicit relative importance weights (RIWs) for avoiding 11 potential HF symptoms and outcomes using best-worst scaling. The survey also included questions about individuals' HF knowledge, and demographic and disease-experience characteristics...
July 13, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28686707/molecular-characterization-of-occult-hepatitis-b-virus-infection-in-patients-with-end-stage-liver-disease-in-colombia
#14
Julio Cesar Rendon, Fabian Cortes-Mancera, Juan Carlos Restrepo-Gutierrez, Sergio Hoyos, Maria-Cristina Navas
BACKGROUND: Hepatitis B virus (HBV) occult infection (OBI) is a risk factor to be taken into account in transfusion, hemodialysis and organ transplantation. The aim of this study was to identify and characterize at the molecular level OBI cases in patients with end-stage liver disease. METHODS: Sixty-six liver samples were obtained from patients with diagnosis of end-stage liver disease submitted to liver transplantation in Medellin (North West, Colombia). Samples obtained from patients who were negative for the surface antigen of HBV (n = 50) were tested for viral DNA detection by nested PCR for ORFs S, C, and X and confirmed by Southern-Blot...
2017: PloS One
https://www.readbyqxmd.com/read/28676058/chemical-constituents-antibacterial-and-antioxidant-properties-of-the-essential-oil-flower-of-tagetes-minuta-grown-in-cala-community-eastern-cape-south-africa
#15
Aboi Igwaran, Benson Chucks Iweriebor, Sunday Ofuzim Okoh, Uchechukwu Uchechukwu Nwodo, Larry Chikwelu Obi, Anthony Ifeanyi Okoh
BACKGROUND: Tagetes minuta has a long record of human use for the treatment of stomach and intestinal diseases. Most drugs used for diseases treatment are less efficacious with side effects and this brought the search for new treatment regimens mainly from medicinal plants. METHOD: The essential oil (EO) was extracted by Clevenger's-type apparatus and its chemical composition, antioxidant and antibacterial properties were determined by GC-MS, spectrophotometric and broth dilution methods respectively...
July 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28673499/occult-hepatitis-b-infection-and-transfusion-transmission-risk
#16
D Candotti, L Boizeau, S Laperche
Advances in serology and viral nucleic acid testing (NAT) over the last decades significantly reduced the risk of transfusion-transmitted hepatitis B virus (HBV). The combination of HBsAg testing and NAT efficiently prevents the majority of HBV transmission. However, a specific residual risk remains associated with extremely low viral DNA levels in blood donors with occult HBV infection (OBI) that are intermittently or not detectable even by highly sensitive individual donation (ID) NAT. Studies have reported HBV transfusion-transmission with blood components from donors with OBI that contained low amount of viruses (<200 virions)...
June 30, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28668951/the-relationship-between-age-common-bile-duct-diameter-and-diagnostic-probability-in-suspected-choledocholithiasis
#17
Efstathios Karamanos, Kenji Inaba, Regan J Berg, Shelby Resnick, Obi Okoye, Sophoclis Alexopoulos, Konstantinos Chouliaras, Demetrios Demetriades
BACKGROUND: Aging has been associated with increasing common bile duct (CBD) diameter and reported as independently predictive of the likelihood of choledocolithiasis. These associations are controversial with uncertain diagnostic utility in patients presenting with symptomatic disease. The current study examined the relationship between age, CBD size, and the diagnostic probability of choledocolithiasis. METHODS: Symptomatic patients undergoing evaluation for suspected choledocolithiasis from January 2008 to February 2011 were reviewed...
July 1, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28658511/occult-hepatitis-b-virus-infection-in-immunized-children-born-to-carrier-mothers
#18
Koji Yokoyama, Hideki Kumagai, Masaharu Takahashi, Shigeo Nagashima, Hiroaki Okamoto, Takanori Yamagata
BACKGROUND: The prevalence of occult hepatitis B virus (HBV) infection (OBI) in children who develop the infection via mother-to-child transmission (MTCT) despite immunoprophylaxis remains controversial and is still unknown in Japan. The aim of this study was to determine the OBI prevalence among such children in Japan and identify the genomic mutations that might be associated with the pathogenesis of OBI in children. METHODS: The data on 158 children born to HBV carrier mothers and who received complete passive-active immunoprophylaxis after birth 2002-2014 were reviewed...
June 28, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28656932/patterns-of-gestational-weight-gain-and-its-association-with-birthweight-in-nigeria
#19
C I Onwuka, E O Ugwu, H E Onah, S N Obi, C I Onwuka, I E Menuba, I I Okafor
BACKGROUND: Despite the increasing global importance of gestational weight gain (GWG) and its impact on birthweight, little is known about the patterns of GWG in African populations. OBJECTIVES: To determine the pattern of GWG and its association with birthweight in Nigeria. METHODS: It was a longitudinal study of 200 pregnant women receiving antenatal care at two tertiary hospitals in Enugu, south eastern Nigeria. The women were consecutively recruited at <14 weeks gestation and their body mass indexes recorded upon recruitment...
June 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28641751/fetal-imaging-and-therapy-for-cdh-current-status
#20
Titilayo Oluyomi-Obi, Tim Van Mieghem, Greg Ryan
In congenital diaphragmatic hernia (CDH), herniation of the abdominal organs into the fetal chest causes pulmonary hypoplasia and pulmonary hypertension, the main causes of neonatal mortality. As antenatal ultrasound screening improves, the risk of postnatal death can now be better predicted, allowing for the identification of fetuses that might most benefit from a prenatal intervention. Fetoscopic tracheal occlusion is being evaluated in a large international randomized controlled trial. We present the antenatal imaging approaches that can help identify fetuses that might benefit from antenatal therapy, and review the evolution of fetal surgery for CDH to date...
June 2017: Seminars in Pediatric Surgery
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