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https://www.readbyqxmd.com/read/29036995/-association-of-alcohol-use-and-incidence-of-type-2-diabetes-mellitus-in-the-middle-aged-and-elderly-male-population-a-prospective-cohort-study
#1
Y Z Zhang, Y Q Yu, Y Yuan, M A He, T C Wu
Objective: To investigate the association between alcohol use and incidence of type 2 diabetes mellitus (T2DM) in the middle-aged and elderly male population. Methods: All participants were from Dongfeng-Tongji cohort, 27 009 retired employees from Dongfeng Motor Corporation in Hubei Province were enrolled in the Dongfeng-Tongji cohort baseline survey in 2008. In baseline study, information of alcohol use and other covariates were collected by semi-structured questionnaire and all participants completed physical examination including the test of fasting glucose and blood lipid levels...
October 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29033312/higher-serum-albumin-was-related-with-diabetes-incidence-and-the-impact-of-bmi-changes-based-on-cohort-study-of-18-384-chinese-male-elderly
#2
Miao Liu, Jingping Tang, Jing Zeng, Yao He
AIMS: Albumin (ALB) was a useful marker of nutrition and general health status. However, the conclusion about the association between ALB and diabetes was inconsistent, and little information was known about the elderly. METHODS: A cohort study based on 18,384 army cadres was conducted Beijing, from 2009 to 2013. RESULTS: The mean age of the total 18,384 participants was 71±14years, and the mean ALB concentration was 44.33±3.94g/L at baseline...
September 6, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29030131/effects-of-diabetes-mellitus-and-systemic-arterial-hypertension-on-elderly-patients-hearing
#3
Laurie Penha Rolim, Alessandra Giannella Samelli, Renata Rodrigues Moreira, Carla Gentile Matas, Itamar de Souza Santos, Isabela Martins Bensenor, Paulo Andrade Lotufo
INTRODUCTION: Chronic diseases can act as an accelerating factor in the auditory system degeneration. Studies on the association between presbycusis and diabetes mellitus and systemic arterial hypertension have shown controversial conclusions. OBJECTIVE: To compare the initial audiometry (A1) with a subsequent audiometry (A2) performed after a 3 to 4-year interval in a population of elderly patients with diabetes mellitus and/or systemic arterial hypertension, to verify whether hearing loss in these groups is more accelerated when compared to controls without these clinical conditions...
September 21, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29028677/are-people-with-a-history-of-disease-more-susceptible-to-a-short-term-exposure-to-asian-dust-a-case-crossover-study-among-the-elderly-in-japan
#4
Saori Kashima, Takashi Yorifuji, Etsuji Suzuki
BACKGROUND: Factors influencing the susceptibility of the elderly to the adverse health effects of short-term exposure to desert dust have yet to be explored. We aimed to identify the disease histories that increase the susceptibility of the elderly to disease onset induced by dust events. METHODS: We used a time-stratified case-crossover design using data on 17,874 elderly residents (≥65 years) of Okayama, Japan, who were transported to hospital emergency rooms because of cardiovascular and respiratory diseases between 2006 and 2010...
October 2017: Epidemiology
https://www.readbyqxmd.com/read/29028277/associations-between-daily-cooking-duration-and-the-prevalence-of-diabetes-and-pre-diabetes-in-a-middle-aged-and-elderly-chinese-population-a-cross-sectional-study
#5
Fei Wang, Jing Wang, Yaru Li, Xu Han, Hua Hu, Caizheng Yu, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Weihong Chen, Yuan Liang, Huan Guo, Xiaomin Zhang, Handong Yang, Tangchun Wu, Meian He
Experimental and epidemiological studies indicated that ambient air pollution was positively associated with diabetes. Few studies investigated the associations between household air pollution, for example, daily cooking duration and diabetes or prediabetes. We conducted a cross-sectional study to investigate the associations of daily cooking duration with the prevalence of diabetes and prediabetes among a middle-aged and elderly population. A total of 26,089 individuals (11,250 males and 14,839 females) derived from the Dongfeng-Tongji cohort study were included...
October 13, 2017: Indoor Air
https://www.readbyqxmd.com/read/29026833/primary-prevention-of-cardiovascular-disease-in-older-adults-in-china
#6
REVIEW
Jian Yong, Dong Lin, Xue-Rui Tan
Over the past two decades, the percentage of Chinese who is 60 years or older has increased from 5.2% in 1995 to 10.5% in 2015. Approximately 16% of the population in China was 60 years old and above in 2015. Since 1990, cardiovascular disease (CVD) has been the leading cause of death in China. Cardiovascular medications of older adults are usually more complicated than younger age groups due to polypharmacy, the presence of comorbidities and more susceptible to treatment-related adverse outcomes. Therefore, effective primary prevention of CVD for older adults is important in sustaining the health of older adults and reducing the burden of the healthcare system...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29026759/quality-of-life-among-elderly-population-residing-in-urban-field-practice-area-of-a-tertiary-care-institute-of-ahmedabad-city-gujarat
#7
Venu R Shah, Donald S Christian, Arpit C Prajapati, Mansi M Patel, K N Sonaliya
INTRODUCTION: Overall improvement in the living standards of country's population is leading to longer life expectancy. To emphasize the medical and psychological difficulties faced by geriatric people is essential to know status of their quality of life (QOL). METHODOLOGY: A community-based cross-sectional study was carried out at urban field practice area of one of the teaching institutes of Ahmedabad, Gujarat. Considering the prevalence of about 7.5% of 60 years and above people sample size of 250 was calculated...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29026148/exclusive-and-combined-use-of-statins-and-aspirin-and-the-risk-of-pancreatic-cancer-a-case-control-study
#8
Livia Archibugi, Matteo Piciucchi, Serena Stigliano, Roberto Valente, Giulia Zerboni, Viola Barucca, Michele Milella, Patrick Maisonneuve, Gianfranco Delle Fave, Gabriele Capurso
Data on the association between aspirin and statin use and Pancreatic Ductal AdenoCarcinoma (PDAC) risk are conflicting. These drugs are often co-prescribed, but no studies evaluated the potential combined or confounding effect of the two at the same time. We aimed to investigate the association between aspirin and statin exclusive and combined use and PDAC occurrence. Data on environmental factors, family and medical history were screened in a case-control study. PDAC cases were matched to controls for age and gender...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29025285/safety-and-efficacy-of-canagliflozin-in-elderly-patients-with-type-2-diabetes-mellitus-a-1-year-post-marketing-surveillance-in-japan
#9
Maki Goda, Tomoko Yamakura, Kazuyo Sasaki, Takumi Tajima, Makoto Ueno
Objective To evaluate the safety and efficacy of canagliflozin in elderly patients with type 2 diabetes mellitus (T2DM) in clinical settings. Methods We conducted a 1-year post-marketing surveillance (PMS) of canagliflozin in almost all the elderly patients (≥65 years old) with T2DM who began taking canagliflozin during the first 3 months after its launch in Japan. The main outcomes included the incidences of adverse drug reactions (ADRs), serious ADRs and the changes of laboratory tests as well as efficacy variables...
October 13, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29023983/age-vascular-health-and-alzheimer-s-disease-biomarkers-in-an-elderly-sample
#10
Prashanthi Vemuri, Timothy G Lesnick, Scott A Przybelski, David S Knopman, Val J Lowe, Jonathan Graff-Radford, Rosebud O Roberts, Michelle M Mielke, Mary M Machulda, Ronald C Petersen, Clifford R Jack
OBJECTIVE: To investigate the associations between age, vascular health, and Alzheimer's disease (AD) imaging biomarkers in an elderly sample. METHODS: We identified 430 individuals along the cognitive continuum aged>60 years with amyloid-PET, Tau-PET, and MRI scans from the population-based Mayo Clinic Study of Aging. A subset of 329 individuals had FDG-PET. We ascertained presently existing cardiovascular and metabolic conditions (CMC) from healthcare records and used the summation of presence/absence of hypertension, hyperlipidemia, cardiac-arrhythmias, coronary artery disease, congestive heart failure, diabetes mellitus, and stroke as a surrogate for vascular health...
October 10, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29023744/the-relationship-of-oral-health-with-general-health-and-ncds-a-brief-review
#11
Christof Dörfer, Christoph Benz, Jun Aida, Guillaume Campard
Oral health is closely related to systemic health. Periodontitis, a chronic inflammatory disease which is highly prevalent worldwide, interacts with a variety of noncommunicable diseases (NCDs). It is a risk factor in the complex pathogenesis of diabetes mellitus and cardiovascular disease and plays a role in the development of endocarditis and recurrent pneumonia in elderly people. However, the available data may be interpreted in different ways, and more and better-designed studies are still needed to answer relevant questions about the causal role of periodontitis in NCDs...
September 2017: International Dental Journal
https://www.readbyqxmd.com/read/29022298/patient-awareness-of-cataract-and-age-related-macular-degeneration-among-the-korean-elderly-a-population-based-study
#12
Hankil Lee, Yong Jung Jang, Hyung Keun Lee, Hye Young Kang
PURPOSE: Age-related eye disease is often considered part of natural aging. Lack of awareness of eye conditions can result in missed treatment. We investigated the rates of awareness of cataract and age-related macular degeneration, the most common age-related eye-diseases, and the associated factors among elderly Koreans. METHODS: We identified 7,403 study subjects (≥40 years old) with cataract or age-related macular degeneration based on ophthalmic examination results during the 5th Korean National Health and Nutrition Examination Survey conducted between 2010 and 2012...
August 26, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/29019063/statin-prescribing-in-the-elderly-special-considerations
#13
REVIEW
M Leya, N J Stone
PURPOSE OF REVIEW: Our aim was to examine the current evidence behind prescribing statins to individuals over 65 years of age with emphasis on those older than 75. Individuals over 75 years of age may often have multiple comorbidities and take many medications. Additionally, they are often underrepresented in randomized controlled trials (RCTs) of statins in older populations. While results of RCTs demonstrate the benefit of statin therapy in both primary and secondary prevention patients, clinicians must more carefully consider adverse effects and drug-drug interactions before prescribing statin therapy as well as determining the intensity in older individuals...
October 11, 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29018146/anca-and-iga-glomerulonephritis-all-in-one-prognosis-and-complications
#14
Pitchaphon Nissaisorakarn, Vivette D'Agati, Kisra Anis, Belinda Jim
We present the case of a 75-year-old Hispanic woman with known stage 3 chronic kidney disease, long-standing hypertension and type 2 diabetes mellitus who presented with right-sided abdominal pain and acute kidney injury, nephrotic range proteinuria with positive antimyeloperoxidase antibody. A renal biopsy revealed IgA nephropathy with superimposed pauci-immune antineutrophilic cytoplasmic antibody (ANCA)-associated crescentic glomerulonephritis. The patient was treated with pulse intravenous methylprednisolone, cyclophosphamide and plasmapheresis...
October 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29018129/neuroimaging-correlates-of-cerebral-microbleeds-the-aric-study-atherosclerosis-risk-in-communities
#15
Jonathan Graff-Radford, Jeannette Simino, Kejal Kantarci, Thomas H Mosley, Michael E Griswold, B Gwen Windham, A Richey Sharrett, Marilyn S Albert, Rebecca F Gottesman, Clifford R Jack, Prashanthi Vemuri, David S Knopman
BACKGROUND AND PURPOSE: Cerebral microbleed (CMB) location (deep versus strictly lobar) may elucidate underlying pathology with deep CMBs being more associated with hypertensive vascular disease and lobar CMBs being more associated with cerebral amyloid angiopathy. The objective of this study was to determine whether neuroimaging signs of vascular disease and Alzheimer pathology are associated with different types of CMBs. METHODS: Among 1677 nondemented ARIC (Atherosclerosis Risk in Communities) participants (mean age=76±5 years; 40% men; 26% black) with 3-Tesla MRI scans at the fifth examination (2011-2013), we fit multinomial logistic regression models to quantify relationships of brain volumes (Alzheimer disease signature regions, total gray matter, frontal gray matter, and white matter hyperintensity volumes), infarct frequencies (lacunar, nonlacunar, and total), and apolipoprotein E(number of ε4 alleles) with CMB location (none, deep/mixed, or strictly lobar CMBs)...
October 10, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28994646/envisioning-eye-care-from-a-rural-perspective-a-photovoice-project-from-india
#16
Padmaja Kumari Rani, Rajita Kasoju, Venkatiah Komara, Raju Kothapalli, Devichandar Choudary, Jyothi Korani, Jachin D Williams, Clifton M Schor, Nance Wilson
Background To understand barriers and promoters for accessing eye care by rural communities, we used a modified approach to Photovoice, a community-based participatory action research approach Methods Community members took photographs and wrote or spoke stories based upon a series of questions intended to facilitate deeper thinking. Fifteen rural paramedical team members who were affiliated with the rural network of L V Prasad Eye Institute, and 60 people from four villages reported barriers and promoters for eye care access for 20 villages Results Important barriers for accessing eye care included the following: no caretaker at home for grandchildren except for the grandparent(s), alcoholism, uncontrolled blood pressure, inadequate diabetes management, lack of escort for blind people and elders, affordability, and inadequate clinic staffing during summer season when farming villagers were available...
January 1, 2017: International Quarterly of Community Health Education
https://www.readbyqxmd.com/read/28993578/characterizations-of-oral-microbiota-in-elderly-nursing-home-residents-with-diabetes
#17
Taiji Ogawa, Mariko Honda-Ogawa, Kazunori Ikebe, Yumiko Notomi, Yoshiko Iwamoto, Itsuki Shirobayashi, Seiko Hata, Masahito Kibi, Shizuko Masayasu, Satoshi Sasaki, Shigetada Kawabata, Yoshinobu Maeda
Over 700 bacterial species have been detected in the oral cavity. Several studies have suggested that periodontitis is associated with systemic disorders such as diabetes mellitus, indicating a key role for oral microbiota in human health. However, the relationship between oral microbiota and diabetes has not been well clarified. Therefore, we conducted microbiome analysis of saliva samples obtained from 15 elderly residents (3 with type 2 diabetes mellitus [DM] and 12 without diabetes [non-DM]) at three different nursing homes, as well as 9 young healthy controls (HC)...
October 6, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28993003/the-fasting-serum-triglyceride-levels-of-elderly-population-with-different-progression-stages-of-diabetes-mellitus-in-china
#18
Yi-Xiong Gao, Qingqing Man, Shanshan Jia, Yuqian Li, Lixiang Li, Jian Zhang
AIMS: This cross-sectional study aimed to investigate triglyceride level among Chinese elderly population with different diabetic progressions and related factors of triglyceride. METHODS: Study participants (≥65years) were recruited from a nationwide cross-sectional surveillance and were divided into four subgroups according to diabetic progression. Their information was obtained via questionnaire and physical examination. Their lipids in fasting serum samples were analyzed...
August 26, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28992666/-an-increase-in-cases-of-bladder-tamponade-due-to-cystitis-among-elderly-women-and-clinical-background-factors
#19
Kazunari Tsuchihashi, Yuki Makino, Masahiro Emura, Kazutaka Kida, Yosuke Shimizu, Sojun Kanamaru, Ryo Iguchi, Tetsuya Noguchi, Miharu Sasaki, Noriyuki Ito
Bladder tamponade is thought to be caused mainly by bladder cancer or radiation cystitis. However, in women, it may often be caused by cystitis in clinical settings. This has not been noted in previous reports of bladder tamponade in Japan. Thus, we retrospectively analyzed the clinical features of 83 male and 41 female patients with bladder tamponade. Seventy-four patients were treated at Nishi-Kobe Medical Center between April 2005 and March 2015, and 50 were treated at Shizuoka City Shizuoka Hospital between November 2008 and March 2015...
September 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28992236/bedroom-light-exposure-at-night-and-the-incidence-of-depressive-symptoms-a-longitudinal-study-of-the-heijo-kyo-cohort
#20
Kenji Obayashi, Keigo Saeki, Norio Kurumatani
Previous studies have indicated that minimal exposure to light-at-night increases depression risk, even at 5 lux, in nocturnal and diurnal mammals. Although such low level light-at-night may be effective for human circadian physiology, the association between exposure to light-at-night and depressive symptoms remains uncertain. Bedroom light intensity was measured objectively and depressive symptoms were assessed between 2010-2014 in Nara, Japan. Of 863 participants (mean age, 71.5 years) who did not have depressive symptoms at baseline, 73 participants reported development of depressive symptoms during follow-up (median, 24 months)...
July 31, 2017: American Journal of Epidemiology
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