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https://www.readbyqxmd.com/read/28922126/functional-contour-following-via-haptic-perception-and-reinforcement-learning
#1
Randall B Hellman, Cem Tekin, Mihaela van der Schaar, Veronica J Santos
Many tasks involve the fine manipulation of objects despite limited visual feedback. In such scenarios, tactile and proprioceptive feedback can be leveraged for task completion. We present an approach for real-time haptic perception and decision-making for a haptics-driven, functional contour-following task: the closure of a ziplock bag. This task is challenging for robots because the bag is deformable, transparent, and visually occluded by artificial fingertip sensors that are also compliant. A deep neural net classifier was trained to estimate the state of a zipper within a robot's pinch grasp...
September 18, 2017: IEEE Transactions on Haptics
https://www.readbyqxmd.com/read/28921549/%C3%AE-flucs-brighter-photinus-pyralis-firefly-luciferases-identified-by-surveying-consecutive-single-amino-acid-deletion-mutations-in-a-thermostable-variant
#2
Lisa M Halliwell, Amit P Jathoul, Jack P Bate, Harley L Worthy, James C Anderson, Dafydd D Jones, James A H Murray
The bright bioluminescence catalysed by Photinus pyralis firefly luciferase (Fluc) enables a vast array of life science research such as bioimaging in live animals and sensitive in vitro diagnostics. The effectiveness of such applications is improved using engineered enzymes that to date have been constructed using amino acid substitutions. We describe ΔFlucs: consecutive single amino acid deletion mutants within 6 loop structures of the bright and thermostable x11 Fluc. Deletion mutations are a promising avenue to explore new sequence and functional space and isolate novel mutant phenotypes...
September 16, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28920911/efficient-online-learning-algorithms-based-on-lstm-neural-networks
#3
Tolga Ergen, Suleyman Serdar Kozat
We investigate online nonlinear regression and introduce novel regression structures based on the long short term memory (LSTM) networks. For the introduced structures, we also provide highly efficient and effective online training methods. To train these novel LSTM-based structures, we put the underlying architecture in a state space form and introduce highly efficient and effective particle filtering (PF)-based updates. We also provide stochastic gradient descent and extended Kalman filter-based updates. Our PF-based training method guarantees convergence to the optimal parameter estimation in the mean square error sense provided that we have a sufficient number of particles and satisfy certain technical conditions...
September 13, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28920443/four-fallacies-and-an-oversight-searching-for-martian-life
#4
J D Rummel, C A Conley
While it is anticipated that future human missions to Mars will increase the amount of biological and organic contamination that might be distributed on that planet, robotic missions continue to grow in capability and complexity, requiring precautions to be taken now to protect Mars, and particularly areas of Mars that might be Special Regions. Such precautionary cleanliness requirements for spacecraft have evolved over the course of the space age, as we have learned more about planetary environments, and are the subject of regular deliberations and decisions sponsored by the Committee on Space Research (COSPAR)...
September 16, 2017: Astrobiology
https://www.readbyqxmd.com/read/28918701/supporting-family-involvement-in-long-term-residential-care-promising-practices-for-relational-care
#5
Rachel Barken, Ruth Lowndes
Family members and friends provide significant support for older relatives in long-term residential care (LTRC). Yet, they occupy ambiguous positions in these settings, and their relationships with LTRC staff can involve conflicts and challenges. Based on an ethnographic project carried out in North America and Europe, this article identifies practices that promote meaningful family participation in care home life. We consider instances of rewarding family involvement upon admission to LTRC, throughout the time a relative is living in a care home, and during the final stages of life...
September 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28916960/a-novel-approach-using-the-enhanced-view-totally-extraperitoneal-etep-technique-for-laparoscopic-retromuscular-hernia-repair
#6
Igor Belyansky, Jorge Daes, Victor Gheorghe Radu, Ramana Balasubramanian, H Reza Zahiri, Adam S Weltz, Udai S Sibia, Adrian Park, Yuri Novitsky
BACKGROUND: The enhanced-view totally extraperitoneal (eTEP) technique has been previously described for Laparoscopic Inguinal Hernia Repair. We present a novel application of the eTEP access technique for the repair of ventral and incisional hernias. METHODS: Retrospective review of consecutive laparoscopic retromuscular hernia repair cases utilizing the eTEP access approach from five hernia centers between August 2015 and October 2016 was conducted. Patient demographics, hernia characteristics, operative details, perioperative complications, and quality of life outcomes utilizing the Carolina's Comfort Scale (CCS) were included in our data analysis...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28913289/communicating-hydrocephalus-onset-following-a-traumatic-tension-pneumocephalus
#7
Jin-Sung Lee, Sora Ahn, Ki Seong Eom
The entrapment of intracranial air from the check valve system results in a tension pneumocephalus. It should be distinguished from simple pneumocephalus because they are intracranial space-occupying masses that can threaten life. Communicating hydrocephalus is a serious and frequent complication of post-traumatic head injury. Head injury is one of the most common causes in etiopathogenesis of communicating hydrocephalus. Here, we describe a case of a 65-year-old man who developed communicating hydrocephalus after a post-traumatic tension pneumocephalus...
December 2016: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28912618/moral-theological-analysis-of-direct-versus-indirect-abortion
#8
John M Haas
Cases of a vital conflict, where the lives of both the mother and child are at risk during pregnancy, have been the subject of recent vigorous debate. The basic principles put forth in the Ethical and Religious Directives are reviewed, as is the principle of double effect. An illustrative case of severe cardiomyopathy in a pregnant woman is described and it is noted that the principle of double effect would not apply. Counter arguments are noted, focusing on Martin Rhonheimer who posits that in the case of vital conflicts, such as performing a craniotomy on a baby stuck in the birth canal, taking the baby's life does not constitute a direct abortion because moral norms do not apply in the extreme conflict situation where both mother and child will die...
August 2017: Linacre Quarterly
https://www.readbyqxmd.com/read/28911272/exploring-health-navigating-design-momentary-contentment-in-a-cancer-context
#9
Ulrika Sandén, Lars Harrysson, Hans Thulesius, Fredrik Nilsson
PURPOSE: The technocratic and medicalized model of healthcare is rarely optimal for patients. By connecting two different studies we explore the possibilities of increasing quality of life in cancer care. METHODS: The first study captures survival strategies in a historically isolated Arctic village in Norway resulting in Momentary contentment theory, which emerged from analysing four years of participant observation and interview data. The second study conceptualizes everyday life of cancer patients based on in-depth interviews with 19 cancer patients; this was conceptualized as Navigating a new life situation...
2017: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/28910777/haptic-collision-detection-on-disjoint-objects-with-overlapping-and-inclusive-bounding-volumes
#10
Lei Wei, Hailing Zhou, Saeid Nahavandi
This paper presents a method to alleviate performance degradation issues of Haptic Collision Detection when the Bounding Volumes or Bounding Volume Hierarchies of multiple disjoint objects are overlapping or inclusive and force the Haptic Collision Detection methods into narrow phase collision detection with all involved objects. The proposed method aims to generate tighter, mutually exclusive Bounding Volumes at the pre-processing stage, and to quickly cull irrelevant nearby objects at the broad phase to ensure that the Haptic Collision Detection methods will not be overloaded with unnecessary narrow phase collision detection...
September 8, 2017: IEEE Transactions on Haptics
https://www.readbyqxmd.com/read/28910473/optimization-of-simulation-and-moulage-in-military-related-medical-training
#11
Christopher Petersen, Stephen C Rush, Isabelle Gallo, Bryan Dalere, Brian Staak, Litt Moore, Win Kerr, Matthew Chandler, Will Smith
Preparation of Special Operations Forces (SOF) Medics as first responders for the battle space and austere environments is critical to optimize survival and quality of life for our Operators who may sustain serious and complex wounding patterns and illnesses. In the absence of constant clinical exposure for these medics, it is necessary to maximize all available training opportunities. The incorporation of scenario-based training helps weave together teamwork and the ability to practice treatment protocols in a tactical, controlled training environment to reproduce, to some degree, the environment in and stressors under which care will need to be delivered...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28904122/evolution-of-polymer-formation-within-the-actin-superfamily
#12
Patrick R Stoddard, Tom A Williams, Ethan Garner, Buzz Baum
While many are familiar with actin as a well-conserved component of the eukaryotic cytoskeleton, it is less often appreciated that actin is a member of a large superfamily of structurally related protein families found throughout the tree of life. Actin-related proteins include chaperones, carbohydrate kinases, and other enzymes, as well as a staggeringly diverse set of proteins that use the energy from ATP hydrolysis to form dynamic, linear polymers. Despite differing widely from one another in filament structure and dynamics, these polymers play important roles in ordering cell space in bacteria, archaea, and eukaryotes...
September 15, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28903311/development-of-hepatoma-derived-bidirectional-oval-like-cells-as-a-model-to-study-host-interactions-with-hepatitis-c-virus-during-differentiation
#13
Masahiko Ito, Suofeng Sun, Takasuke Fukuhara, Ryosuke Suzuki, Miho Tamai, Toyohiko Yamauchi, Kenji Nakashima, Yoh-Ichi Tagawa, Shigetoshi Okazaki, Yoshiharu Matsuura, Takaji Wakita, Tetsuro Suzuki
Directed differentiation of human stem cells including induced pluripotent stem cells into hepatic cells potentially leads to acquired susceptibility to hepatitis C virus (HCV) infection. However, cellular determinants that change their expression during cell reprogramming or hepatic differentiation and are pivotal for supporting the HCV life cycle remain unclear. In this study, by introducing a set of reprogramming factors, we established HuH-7-derived oval-like cell lines, Hdo-17 and -23, which possess features of bipotential liver precursors...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28901873/homeopathy-for-mexicans-medical-popularisation-commercial-endeavours-and-patients-choice-in-the-mexican-medical-marketplace-1853-1872
#14
Jethro Hernández Berrones
This paper focuses on homeopaths' strategies to popularise homeopathy from 1850 to 1870. I argue that homeopaths created a space for homeopathy in Mexico City in the mid-nineteenth century by facilitating patients' access to medical knowledge, consultation and practice. In this period, when national and international armed conflicts limited the diffusion and regulation of academic medicine, homeopaths popularised homeopathy by framing it as a life-enhancing therapy with tools that responded to patients' needs...
October 2017: Medical History
https://www.readbyqxmd.com/read/28900400/fractional-stability-of-trunk-acceleration-dynamics-of-daily-life-walking-toward-a-unified-concept-of-gait-stability
#15
Espen A F Ihlen, Kimberley S van Schooten, Sjoerd M Bruijn, Mirjam Pijnappels, Jaap H van Dieën
Over the last decades, various measures have been introduced to assess stability during walking. All of these measures assume that gait stability may be equated with exponential stability, where dynamic stability is quantified by a Floquet multiplier or Lyapunov exponent. These specific constructs of dynamic stability assume that the gait dynamics are time independent and without phase transitions. In this case the temporal change in distance, d(t), between neighboring trajectories in state space is assumed to be an exponential function of time...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28899547/linear-dimensions-of-normal-upper-airway-structure-by-magnetic-resonance-imaging-in-chinese-han-infants-and-preschool-children
#16
Xiaoli Yi, Linyin Yao, Xinyu Yuan, Yongxiang Wei, Zhenchang Wang
OBJECTIVES: To establish normative data of upper airway structure in Chinese Han infants and preschool children. METHODS: Magnetic resonance imaging (MRI) scans of 521 Chinese Han infants and preschool children (225 girls, 296 boys) aged from 1 day to 72 months were selected from the children who underwent head MRI at the Capital Institute of Pediatrics Affiliated Children Hospital, Beijing, China. No subjects had sleep-disordered breathing or associated conditions that may have affected the upper airway anatomy...
September 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28895124/ecological-opportunity-alters-the-timing-and-shape-of-adaptive-radiation
#17
Edward D Burress, Milton Tan
The uneven distribution of diversity is a conspicuous phenomenon across the tree of life. Ecological opportunity is a prominent catalyst of adaptive radiation and therefore may alter patterns of diversification. We evaluated the distribution of shifts in diversification rates across the cichlid phylogeny and the distribution of major clades across phylogenetic space. We also tested if ecological opportunity influenced these patterns. Colonization-associated ecological opportunity altered the tempo and mode of diversification during the adaptive radiation of cichlid fishes...
September 12, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28892662/livestock-drivers-knowledge-about-dairy-cow-fitness-for-transport-a-danish-questionnaire-survey
#18
M S Herskin, A Hels, I Anneberg, P T Thomsen
Dairy cows are transported by road to slaughter after their productive life. Cull cows are vulnerable to transport stress, and can only be transported when fit for the intended journey. However, the decision, as to whether a cow is fit is rather subjective and relies on the farmer and the livestock driver. Using a questionnaire survey, we aimed to describe knowledge about, and experiences with, dairy cow fitness for transport among Danish livestock drivers. During nine days of data collection at the three largest Danish cattle slaughterhouses, 66 drivers (55% of the national population of cattle drivers) answered a questionnaire (response rate: 97%)...
September 5, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28892489/funneled-potential-and-flux-landscapes-dictate-the-stabilities-of-both-the-states-and-the-flow-fission-yeast-cell-cycle
#19
Xiaosheng Luo, Liufang Xu, Bo Han, Jin Wang
Using fission yeast cell cycle as an example, we uncovered that the non-equilibrium network dynamics and global properties are determined by two essential features: the potential landscape and the flux landscape. These two landscapes can be quantified through the decomposition of the dynamics into the detailed balance preserving part and detailed balance breaking non-equilibrium part. While the funneled potential landscape is often crucial for the stability of the single attractor networks, we have uncovered that the funneled flux landscape is crucial for the emergence and maintenance of the stable limit cycle oscillation flow...
September 11, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28890663/cold-homes-fuel-poverty-and-energy-efficiency-improvements-a-longitudinal-focus-group-approach
#20
Charlotte N B Grey, Tina Schmieder-Gaite, Shiyu Jiang, Christina Nascimento, Wouter Poortinga
Cold homes and fuel poverty have been identified as factors in health and social inequalities that could be alleviated through energy efficiency interventions. Research on fuel poverty and the health impacts of affordable warmth initiatives have to date primarily been conducted using quantitative and statistical methods, limiting the way how fuel poverty is understood. This study took a longitudinal focus group approach that allowed exploration of lived experiences of fuel poverty before and after an energy efficiency intervention...
August 2017: Indoor + Built Environment: the Journal of the International Society of the Built Environment
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