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https://www.readbyqxmd.com/read/29331842/predicting-1-year-disability-and-mortality-of-injured-older-adults
#1
Alvin D Jeffery, Mary S Dietrich, Cathy A Maxwell
PURPOSE: The growing incidence of elderly patients injured from falls, combined with a growing understanding of the contribution of cognition and frailty to mortality, prompted this work. Our objective was to develop a clinical risk prediction model for prognosticating disability and mortality among injured older adults 1 year after hospitalization. METHODS: Secondary analysis of prospective longitudinal data from an urban Level 1 trauma center. A proportional odds regression model was used to model mortality and functional status as ordinal outcomes...
January 6, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29330073/the-association-of-clinic-based-mobility-tasks-and-measures-of-community-performance-and-risk
#2
M L Callisaya, J Verghese
INTRODUCTION: Gait speed is recognized as an important predictor of adverse outcomes in older people. However, it is unknown if other more complex mobility tasks are better predictors of such outcomes. OBJECTIVE: To examine a range of clinic-based mobility tests and determine which were most strongly associated with measures of community performance and risk (CP&R). DESIGN: Cross-sectional study SETTING: Central Control Mobility and Aging Study, Westchester County, New York PARTICIPANTS: Aged ≥ 65 years (n=424) METHODS: Clinic-based mobility measures included gait speed measured during normal and dual-task conditions, the Floor Maze Immediate and Delay tasks, and stair ascending and descending...
January 9, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29327266/social-targets-improve-body-based-and-environment-based-strategies-during-spatial-navigation
#3
Esther Kuehn, Xiaoli Chen, Pia Geise, Jan Oltmer, Thomas Wolbers
Encoding the position of another person in space is vital for everyday life. Nevertheless, little is known about the specific navigational strategies associated with encoding the position of another person in the wider spatial environment. We asked two groups of participants to learn the location of a target (person or object) during active navigation, while optic flow information, a landmark, or both optic flow information and a landmark were available in a virtual environment. Whereas optic flow information is used for body-based encoding, such as the simulation of motor movements, landmarks are used to form an abstract, disembodied representation of the environment...
January 11, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29325559/pangenome-analyses-of-the-wheat-pathogen-zymoseptoria-tritici-reveal-the-structural-basis-of-a-highly-plastic-eukaryotic-genome
#4
Clémence Plissonneau, Fanny E Hartmann, Daniel Croll
BACKGROUND: Structural variation contributes substantially to polymorphism within species. Chromosomal rearrangements that impact genes can lead to functional variation among individuals and influence the expression of phenotypic traits. Genomes of fungal pathogens show substantial chromosomal polymorphism that can drive virulence evolution on host plants. Assessing the adaptive significance of structural variation is challenging, because most studies rely on inferences based on a single reference genome sequence...
January 11, 2018: BMC Biology
https://www.readbyqxmd.com/read/29325537/factors-associated-with-the-prevalence-of-back-pain-and-work-absence-in-shipyard-workers
#5
Seiji Watanabe, Toshiaki Takahashi, Jun Takeba, Hiromasa Miura
BACKGROUND: We conducted a questionnaire survey of shipyard workers to identify difficulties experienced due to orthopedic or musculoskeletal disorders. METHODS: The subjects were 375 workers (male, 361; female, 14) who worked for a single shipbuilding company. Questionnaire items covered the working environment, including work environment, working posture, and the weight of objects that the subject dealt with, as well as physical and lifestyle characteristics, namely smoking habits, drinking habits, sleeping hours, medications, exercise habits, and any weight gain of 20 kg or more since the age of 20...
January 11, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29321888/a-general-modeling-framework-for-describing-spatially-structured-population-dynamics
#6
Christine Sample, John M Fryxell, Joanna A Bieri, Paula Federico, Julia E Earl, Ruscena Wiederholt, Brady J Mattsson, D T Tyler Flockhart, Sam Nicol, Jay E Diffendorfer, Wayne E Thogmartin, Richard A Erickson, D Ryan Norris
Variation in movement across time and space fundamentally shapes the abundance and distribution of populations. Although a variety of approaches model structured population dynamics, they are limited to specific types of spatially structured populations and lack a unifying framework. Here, we propose a unified network-based framework sufficiently novel in its flexibility to capture a wide variety of spatiotemporal processes including metapopulations and a range of migratory patterns. It can accommodate different kinds of age structures, forms of population growth, dispersal, nomadism and migration, and alternative life-history strategies...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29320788/-competence-based-training-in-the-protected-environment-from-sheltered-space-to-real-life
#7
Christina Quandt, Lars Friedrich
The idea of "learning in a protected environment" is frequently used within the framework of postgradual education in anaesthesiology. However it remains unclear and its exact meaning lies in the eye of the beholder. This paper aims to highlight the definition of the term "protected environment" and its relevance in anaesthesiology. This includes teaching and learning strategies like competence based training and simulation based training in all its variations. We conclude with an attempt to classify the wide variety of Simulators and teaching methods in use including their individual problems transferred into real life situations...
January 2018: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/29318024/congenital-cranial-ventral-abdominal-hernia-peritoneopericardial-diaphragmatic-hernia-and-sternal-cleft-in-a-4-year-old-multiparous-pregnant-queen
#8
Camille Bismuth, Claire Deroy
Case summary: Cranial ventral midline hernias, most often congenital, can be associated with other congenital abnormalities, such as sternal, diaphragmatic or cardiac malformations. A 4-year-old multiparous queen with a substernal hernia was admitted for evaluation of a mammary mass. During CT examination, a bifid sternum, the abdominal hernia containing the intestines, spleen, omentum, three fetuses, a mammary mass and an incidental peritoneopericardial diaphragmatic hernia were identified...
July 2017: JFMS Open Reports
https://www.readbyqxmd.com/read/29316968/improving-the-interoperability-of-biomedical-ontologies-with-compound-alignments
#9
Daniela Oliveira, Catia Pesquita
BACKGROUND: Ontologies are commonly used to annotate and help process life sciences data. Although their original goal is to facilitate integration and interoperability among heterogeneous data sources, when these sources are annotated with distinct ontologies, bridging this gap can be challenging. In the last decade, ontology matching systems have been evolving and are now capable of producing high-quality mappings for life sciences ontologies, usually limited to the equivalence between two ontologies...
January 9, 2018: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/29316334/geriatric-assessment-of-physical-and-cognitive-functioning-in-a-diverse-cohort-of-systemic-lupus-erythematosus-patients-a-pilot-study
#10
Laura Plantinga, Benjamin D Tift, Charmayne Dunlop-Thomas, S Sam Lim, C Barrett Bowling, Cristina Drenkard
OBJECTIVE: To use multi-domain functional assessment, commonly performed in geriatric patients but novel among SLE patients, to better understand functional impairment in SLE. METHODS: We recruited 60 adult participants [aged 20-39 (26.7%), 40-59 (50.0%), and ≥60 (23.3%); 80.0% black; 90.0% female] from an existing cohort of SLE patients. During in-person visits (10/16-4/17), we evaluated physical performance (range 0-4; higher scores = better performance); cognitive performance (five fluid cognition domains; adjusted t-scores); and self-reported measures including physical functioning (t-scores), activities of daily living (ADLs), falls, and life-space mobility...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29315843/ultrahigh-rate-and-long-life-sodium-ion-batteries-enabled-by-engineered-surface-and-near-surface-reactions
#11
Changtai Zhao, Chang Yu, Bo Qiu, Si Zhou, Mengdi Zhang, Huawei Huang, Biqiong Wang, Jijun Zhao, Xueliang Sun, Jieshan Qiu
To achieve the high-power sodium-ion batteries, the solid-state ion diffusion in the electrode materials is a highly concerned issue and needs to be solved. In this study, a simple and effective strategy is reported to weaken and degrade this process by engineering the intensified surface and near-surface reactions, which is realized by making use of a sandwich-type nanoarchitecture composed of graphene as electron channels and few-layered MoS2 with expanded interlayer spacing. The unique 2D sheet-shaped hierarchical structure is capable of shortening the ion diffusion length, while the few-layered MoS2 with expanded interlayer spacing has more accessible surface area and the decreased ion diffusion resistance, evidenced by the smaller energy barriers revealed by the density functional theory calculations...
January 8, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29313679/a-pair-natural-orbitals-restricted-open-shell-configuration-interaction-pno-rocis-approach-for-calculating-x-ray-absorption-spectra-of-large-chemical-systems
#12
Dimitrios Maganas, Serena DeBeer, Frank Neese
In this work, the efficiency of first principles calculations of X-ray absorption spectra of large chemical systems is drastically improved. The approach is based on the previously developed restricted open shell configuration interaction singles (ROCIS) method and its parameterized version, based on a density functional theory (DFT) ground state determinant ROCIS/DFT. The combination of the ROCIS or DFT/ROCIS methods with the well-known machinery of the pair natural orbitals (PNOs) leads to the new PNO-ROCIS and PNO-ROCIS/DFT variants...
January 9, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29311020/is-the-routine-practice-of-antibiotic-prescription-and-microbial-culture-and-antibiotic-sensitivity-testing-justified-in-primary-maxillofacial-space-infection-patients-a-prospective-randomized-clinical-study
#13
Saroj Kumari, Sujata Mohanty, Pankaj Sharma, Jitender Dabas, Sanchaita Kohli, Cathrine Diana
PURPOSE: The purpose of this prospective, randomized, comparative clinical study was to compare treatment outcome of removal of foci and incision and drainage, with or without oral antibiotic therapy, in the management of single primary maxillofacial space infection with a known focus. MATERIALS AND METHODS: A total of 40 patients with single primary maxillofacial space infection with a known infectious focus were divided into two groups, one treated with incision and drainage only, and the other with incision and drainage along with oral antibiotics...
December 20, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29310685/what-are-the-main-inefficiencies-in-trial-conduct-a-survey-of-ukcrc-registered-clinical-trials-units-in-the-uk
#14
Lelia Duley, Alexa Gillman, Marian Duggan, Stephanie Belson, Jill Knox, Alison McDonald, Charlotte Rawcliffe, Joanne Simon, Tim Sprosen, Jude Watson, Wendy Wood
BACKGROUND: The UK Clinical Research Collaboration (UKCRC) registered Clinical Trials Units (CTUs) Network aims to support high-quality, efficient and sustainable clinical trials research in the UK. To better understand the challenges in efficient trial conduct, and to help prioritise tackling these challenges, we surveyed CTU staff. The aim was to identify important inefficiencies during two key stages of the trial conduct life cycle: (i) from grant award to first participant, (ii) from first participant to reporting of final results...
January 8, 2018: Trials
https://www.readbyqxmd.com/read/29310629/the-canadian-urban-environmental-health-research-consortium-a-protocol-for-building-a-national-environmental-exposure-data-platform-for-integrated-analyses-of-urban-form-and-health
#15
Jeffrey R Brook, Eleanor M Setton, Evan Seed, Mahdi Shooshtari, Dany Doiron
BACKGROUND: Multiple external environmental exposures related to residential location and urban form including, air pollutants, noise, greenness, and walkability have been linked to health impacts or benefits. The Canadian Urban Environmental Health Research Consortium (CANUE) was established to facilitate the linkage of extensive geospatial exposure data to existing Canadian cohorts and administrative health data holdings. We hypothesize that this linkage will enable investigators to test a variety of their own hypotheses related to the interdependent associations of built environment features with diverse health outcomes encompassed by the cohorts and administrative data...
January 8, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29307102/sustainability-evaluation-of-mornos-lake-reservoir-greece
#16
Grigoris Rousakis, Ioannis P Panagiotopoulos, Paraskevi Drakopoulou, Panos Georgiou, Dimitrios Nikolopoulos, Nikolaos Mporompokas, Vasilios Kapsimalis, Isidoros Livanos, Ioannis A Morfis, Christos Anagnostou, Maria Koutra
The modern climate trend and population growth have dramatically increased the need for maximization of the net benefit from the existing storage space in freshwater reservoirs. However, sedimentation in reservoirs through physical deposition and/or slope failures is a major threat to their productivity and life expectancy. In this context, the sedimentation impact on the sustainability of Mornos Lake/Reservoir, which is exceptionally vital for the ~ 3.1 million inhabitants of Athens, had to be evaluated...
January 6, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29306539/random-ensemble-learning-for-eeg-classification
#17
Mohammad-Parsa Hosseini, Dario Pompili, Kost Elisevich, Hamid Soltanian-Zadeh
Real-time detection of seizure activity in epilepsy patients is critical in averting seizure activity and improving patients' quality of life. Accurate evaluation, presurgical assessment, seizure prevention, and emergency alerts all depend on the rapid detection of seizure onset. A new method of feature selection and classification for rapid and precise seizure detection is discussed wherein informative components of electroencephalogram (EEG)-derived data are extracted and an automatic method is presented using infinite independent component analysis (I-ICA) to select independent features...
January 3, 2018: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/29301382/hydrogen-bonds-and-life-in-the-universe
#18
Giovanni Vladilo, Ali Hassanali
The scientific community is allocating more and more resources to space missions and astronomical observations dedicated to the search for life beyond Earth. This experimental endeavor needs to be backed by a theoretical framework aimed at defining universal criteria for the existence of life. With this aim in mind, we have explored which chemical and physical properties should be expected for life possibly different from the terrestrial one, but similarly sustained by genetic and catalytic molecules. We show that functional molecules performing genetic and catalytic tasks must feature a hierarchy of chemical interactions operating in distinct energy bands...
January 3, 2018: Life
https://www.readbyqxmd.com/read/29301139/space-and-time-in-the-obsessive-compulsive-phenomenon
#19
Otto Doerr-Zegers
Following the tradition of researchers of the phenomenological-anthropological school such as Straus, von Gebsattel, Tellenbach, and Blankenburg, the author attempts to approach the obsessive-compulsive disorder from a phenomenological perspective. This means setting aside any previous ideas about the phenomenon in question, including genetic, neurobiological, and clinical-statistical considerations. He takes as his starting point a clinically typical case he studied and treated with psychoanalytically oriented psychotherapy for many years...
January 5, 2018: Psychopathology
https://www.readbyqxmd.com/read/29299627/3d-vascular-anatomy-of-the-presacral-space-impact-of-age-and-adiposity
#20
Alexander A Berger, Steven Abramowitch, Pamela A Moalli
INTRODUCTION AND HYPOTHESIS: Defining patient characteristics that alter vascular anatomy at the sacrum is critical for avoiding life-threatening bleeding at the time of sacrocolpopexy. We tested the hypothesis that in thinner/older women, the bifurcations of the aorta and inferior vena cava (IVC) are lower relative to S1 resulting in less space accessible for suture/mesh placement, placing this group at increased risk of major vascular injury. METHODS: In a retrospective cross-sectional study, CT scans were used to make 2D measurements and a 3D model of the aorta/IVC, intervertebral disc space, and bony anatomy using segmentation and modeling software...
January 3, 2018: International Urogynecology Journal
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