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Cervical disk degeneration

Nam-Su Chung, Chang-Hoon Jeon, Yu-Sang Lee, Jang-Ho Park, Han-Dong Lee
STUDY DESIGN: This is a retrospective control study. OBJECTIVE: We aimed to determine whether preexisting cervical disk degeneration is a prognostic factor in Whiplash-associated disorder (WAD). SUMMARY OF BACKGROUND DATA: WAD is a common injury of traffic accident and has a broad range of prognoses. Although numerous studies have investigated prognostic factors in WAD, few have evaluated the effect of preexisting disk degeneration. MATERIALS AND METHODS: This study involved 45 consecutive patients with grade I or II WAD having advanced disk degeneration (at least 1 disk of Miyazaki grade≥III on magnetic resonance imaging) and a control cohort of 52 patients with no or mild disk degeneration (all disks having Miyazaki grades≤II)...
November 30, 2016: Clinical Spine Surgery
Yu Ding, Di-Ke Ruan, Qing He, Li Sheng Hou, Jian Ning Lin, Hong Peng Cui
STUDY DESIGN: The clinical and radiologic data of total disk allografting (TDA) cases were collected and analyzed to explore the correlation between neurological function improvements and imaging changes. OBJECTIVE: The aim of the study was to assess the medium-term and long-term outcome and radiographic character after TDA, and, furthermore, to explore the significance of the changes of imaging signs after the transplantation. SUMMARY OF BACKGROUND DATA: Spinal fusion may result in the adjacent segment degeneration...
November 2016: Clinical Spine Surgery
Lei Kuang, Yuqiao Chen, Bing Wang, Lei Li, Guohua Lü
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To assess the safety and efficacy of cervical disk arthroplasty (CDA) compared with anterior cervical decompression and fusion (ACDF) for the treatment of 2-level cervical spondylopathy. SUMMARY OF BACKGROUND DATA: CDA has emerged as a potential alternative to ACDF in patients with cervical disk degeneration. But there are no published systematic reviews and meta-analyses comparing CDA with ACDF for the treatment of 2-level cervical spondylopathy...
June 10, 2016: Clinical Spine Surgery
Kris Siemionow, Piotr Janusz, Frank M Phillips, Jim A Youssef, Robert Isaacs, Marcin Tyrakowski, Bruce McCormack
Background Indirect posterior cervical nerve root decompression and fusion performed by placing bilateral posterior cervical cages in the facet joints from a posterior approach has been proposed as an option to treat select patients with cervical radiculopathy. The purpose of this study was to report 2-year clinical and radiologic results of this treatment method. Methods Patients who failed nonsurgical management for single-level cervical radiculopathy were recruited. Surgical treatment involved a posterior approach with decortication of the lateral mass and facet joint at the treated level followed by placement of the DTRAX Expandable Cage (Providence Medical Technology, Lafayette, California, United States) into both facet joints...
November 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
Jianfeng Zhang, Fanxin Meng, Yan Ding, Jie Li, Jian Han, Xintao Zhang, Wei Dong
To investigate the outcomes and reliability of hybrid surgery (HS) versus anterior cervical discectomy and fusion (ACDF) for the treatment of multilevel cervical spondylosis and disc diseases.Hybrid surgery, combining cervical disc arthroplasty (CDA) with fusion, is a novel treatment to multilevel cervical degenerated disc disease in recent years. However, the effect and reliability of HS are still unclear compared with ACDF.To investigate the studies of HS versus ACDF in patients with multilevel cervical disease, electronic databases (Medline, Embase, Pubmed, Cochrane library, and Cochrane Central Register of Controlled Trials) were searched...
May 2016: Medicine (Baltimore)
Martin Dostal, Denis Laurent Kaech
Background Anterior cervical diskectomy (ACD) is an established therapy for degenerative cervical radiculopathy and myelopathy. Controversy remains regarding the dynamic or rigid stabilization of the segment. Methods We studied our first 31 patients treated with ACD plus the Dynamic Cervical Implant (DCI) as an alternative to fusion or to arthroplasty, treated between February 2009 and 2011. Radiologic data were collected before and 12 months after surgery. Clinical results were documented 12 months after surgery...
November 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
Yijie Liu, Heng Wang, Xuefeng Li, Jie Chen, Han Sun, Genlin Wang, Huilin Yang, Weimin Jiang
PURPOSE: We aimed to analyze the clinical and radiographic efficacy of a new zero-profile anchored spacer called the ROI-C in anterior discectomy and fusion (ACDF) for multilevel cervical spondylotic myelopathy (MCSM). METHOD: We retrospectively reviewed the clinical, radiological outcomes and complications of multilevel ACDF with the ROI-C or with the polyetheretherketone (PEEK) cages with an anterior plate. From April 2011 to April 2014, 60 patients with MCSM were operated on using ACDF, with the ROI-C in 28 patients and PEEK cages with an anterior plate in 32 patients...
June 2016: European Spine Journal
Cheng Zeng, Jian Xiong, Jeffrey C Wang, Hirokazu Inoue, Yanlin Tan, Haijun Tian, Bayan Aghdasi
Study Design Retrospective cohort study. Objective The objective was to measure the change of flavum ligament diameter during positional changes of the cervical spine using kinetic magnetic resonance imaging (MRI) and to examine the correlational diameter changes of the flavum ligament, disk bulging, and the spinal canal from extension to flexion positions. Methods One hundred eight-nine patients underwent kinetic MRI in neutral, extension, and flexion positions. The diameters of cervical ligamentum flavum, disk bulging, and cervical spinal canal and the disk degeneration grade and Cobb angles were measured from C2-C3 to C7-T1...
March 2016: Global Spine Journal
Sun Qizhi, Sun Lei, Li Peijia, Zhao Hanping, Hu Hongwei, Chen Junsheng, Li Jianmin
STUDY DESIGN: A prospective randomized and controlled study of 30 patients with 2 noncontiguous levels of cervical spondylosis. OBJECTIVE: To compare the clinical outcome between zero-profile devices and artificial cervical disks for noncontiguous cervical spondylosis. SUMMARY OF BACKGROUND DATA: Noncontiguous cervical spondylosis is an especial degenerative disease of the cervical spine. Some controversy exists over the choice of surgical procedure and fusion levels for it because of the viewpoint that the stress at levels adjacent to a fusion mass will increase...
March 2016: Clinical Spine Surgery
Hironobu Sakaura, Toshitada Miwa, Yusuke Kuroda, Tetsuo Ohwada
Study Design Retrospective study. Objective We previously reported that the long-term neurologic outcomes of C3-C6 laminoplasty for cervical spondylotic myelopathy (CSM) are satisfactory, with reduced frequencies of postoperative axial neck pain and kyphotic deformity. However, only 20 patients were included, which is a limitation in that study. The present study investigated the incidence of late neurologic deterioration (LND) of myelopathic symptoms after C3-C6 laminoplasty for CSM and attempted to identify significant risk factors for LND in a larger patient population...
February 2016: Global Spine Journal
Wenjie Wu, Jingtong Lyu, Hao Liu, Xin Rong, Beiyu Wang, Ying Hong, Quan Gong, Tao Li, Limin Liu, Yueming Song, Yong Cai, Wenli Xu
Surgical treatment is one of the effective methods of treatment in cervical spondylosis. The traditional method of operation is decompression fusion; however, this surgery results in restricted movement of cervical vertebra and adjacent segment degeneration. Due to the deficiency of traditional surgery, scholars have widely carried out artificial cervical disk replacement surgery and have achieved good clinical effects. Comparing to the characteristics of the common artificial cervical disk which is used frequently, we developed a new artificial cervical intervertebral disk prosthesis...
September 2015: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Mohammad Ibrahim, Akinobu Suzuki, Kentaro Yamada, Shinji Takahashi, Hiroyuki Yasuda, Sho Dohzono, Tatsuya Koike, Hiroaki Nakamura
STUDY DESIGN: A cross-sectional imaging study. OBJECTIVE: To investigate the relationship between cervical and lumbar spine lesions in patients with rheumatoid arthritis (RA), and to analyze associated factors in those with concurrent cervical and lumbar endplate erosion (EE). SUMMARY OF BACKGROUND DATA: Both the lumbar and cervical spines are often involved in RA, but little is known about the relationship between cervical and lumbar lesions...
April 2015: Journal of Spinal Disorders & Techniques
Haisong Yang, Xuhua Lu, Hailong He, Wen Yuan, Xinwei Wang, Xinyuan Liao, Deyu Chen
STUDY DESIGN: Retrospective case-control study. OBJECTIVE: To clarify the association between plate-to-disc distance (PDD) and adjacent-level ossification development (ALOD) and adjacent segment degeneration (ASD). SUMMARY OF BACKGROUND DATA: Anterior cervical discectomy and fusion with plating provides higher fusion rate and improved alignment but has been reported to result in ALOD and ASD. METHODS: We retrospectively reviewed 218 patients with solid fusion after anterior cervical arthrodesis with plating at our institution between January 2004 and December 2010...
April 1, 2015: Spine
Zhenxiang Zhang, Lei Jiao, Wei Zhu, Yaqing Du, Wenjie Zhang
PURPOSE: The purpose of this retrospective trial was to compare the role of the Bryan with ProDisc-C total disk replacement (TDR). MATERIALS AND METHODS: Data were collected before surgery and 1, 3, 6, 12, and 24 months after surgery. Disability and pain were assessed using the Neck Disability Index (NDI) and the Visual Analog Scale of the neck and of the arm pain. SF-36 outcome measures were obtained including the physical component score as well as the mental component score...
March 2015: Archives of Orthopaedic and Trauma Surgery
Michael S Hisey, Hyun W Bae, Reginald J Davis, Steven Gaede, Greg Hoffman, Kee D Kim, Pierce D Nunley, Daniel Peterson, Ralph F Rashbaum, John Stokes, Donna D Ohnmeiss
STUDY DESIGN: This was a prospective, randomized, controlled multicenter trial. OBJECTIVE: The purpose of this study was to compare clinical outcomes at 4-year follow-up of patients receiving cervical total disk replacement (TDR) with those receiving anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA: ACDF has been the traditional treatment for symptomatic disk degeneration. Several studies found single-level TDR to be as safe and effective as ACDF at ≥2 years follow-up...
May 2015: Journal of Spinal Disorders & Techniques
Paula Martin-Vaquero, Ronaldo C da Costa
OBJECTIVE: To characterize and compare the MRI morphological features of the cervical vertebral column of Great Danes with and without clinical signs of cervical spondylomyelopathy (CSM). DESIGN: Prospective cohort study. ANIMALS: 30 Great Danes (15 clinically normal and 15 CSM-affected). PROCEDURES: All dogs underwent MRI of the cervical vertebral column (C2-3 through T1-2). Features evaluated included sites of subarachnoid space compression, spinal cord compression, or both; degree, cause, and direction of compression; MRI signal changes of the spinal cord; articular process (facet) joint characteristics; internal vertebral venous plexus visibility; and presence of extradural synovial cysts as well as presence and degree of intervertebral disk degeneration and foraminal stenosis...
August 15, 2014: Journal of the American Veterinary Medical Association
Haisong Yang, Xuhua Lu, Wen Yuan, Xinwei Wang, Deyu Chen, Dinglin Zhao
STUDY DESIGN: Retrospective case series study. OBJECTIVE: To clarify the results of a long-term (30 yr) follow-up study of artificial disk replacement (ADR) for the treatment of cervical disk disease. SUMMARY OF BACKGROUND DATA: The use of the ADR procedure has become widespread during the past 10 years. Its purpose is to preserve motion of the functional spinal unit. However, the long-term results are unknown. METHODS: Thirty-seven patients underwent ADR between 1980 and 1985 in the Department of Orthopedic Surgery, Changzheng Hospital...
September 1, 2014: Spine
Aikeremujiang Muheremu, Xiaohui Niu, Zhongyan Wu, Yilixiati Muhanmode, Wei Tian
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) has been used as a gold standard for the treatment of cervical spondylosis, but it may cause complications such as pseudarthrosis and junctional degeneration. Cervical disk arthroplasty (CDA) may help overcome such problems, but there are inconsistencies among the published literature on its effectiveness comparing with ACDF. METHODOLOGY: We searched "PubMed" (2000.1-2013.10), "Medline" (2000.1-2013.10), "Elsevier" (2000...
July 2015: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
D J Wu, K Chen, X Z Wei, H J Ni, S Z Yu, X D Zhu, M Li
Intervertebral disk disease is a common clinical disorder manifested by pain, ataxia, paresis, motor paralysis, and sensorimotor paralysis. The clinical features, diagnosis, and treatment of cervical and thoracolumbar disk disease have been unclear until now. In this study, some differentially expressed genes were identified, and a network was constructed based on these genes. Through the statistical analysis of nodes and the contrast of 2 more connectivity nodes, it was found that the nodes in the network are in an important position and play key roles...
2014: Genetics and Molecular Research: GMR
Rui Shi, Juan Li, Hao Liu, Chen Ding, Tao Hu, Tao Li, Quan Gong
The safety and effectiveness of 2 implantation systems for single-segment cervical disk replacement-the Bryan Cervical Disc System (Medtronic Inc, Minneapolis, Minnesota) and the ACCEL system (Medtronic Inc)-have not been clinically compared. A prospective, nonrandomized controlled study in consecutive patients with a minimum 2-year follow-up was performed. Fifty patients with single-level cervical disk degeneration who responded poorly to conservative treatment and underwent Bryan Cervical Disc replacement were involved...
February 2014: Orthopedics
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