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With Non-ST-Elevation Acute Coronary Syndromes

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https://www.readbyqxmd.com/read/27920547/predictive-value-of-nt-probnp-for-30-day-mortality-in-patients-with-non-st-elevation-acute-coronary-syndromes-a-comparison-with-the-grace-and-timi-risk-scores
#1
Dirk Aam Schellings, Ahmet Adiyaman, Jan-Henk E Dambrink, At Marcel Gosselink, Elvin Kedhi, Vincent Roolvink, Jan Paul Ottervanger, Arnoud Wj Van't Hof
BACKGROUND: The biomarker N-terminal pro-brain natriuretic peptide (NT-proBNP) predicts outcome in patients with non-ST-elevation acute coronary syndromes (NSTE-ACS). Whether NT-proBNP has incremental prognostic value beyond established risk strategies is still questionable. PURPOSE: To evaluate the predictive value of NT-proBNP for 30-day mortality over and beyond the Global Registry of Acute Coronary Events (GRACE) and Thrombolysis In Myocardial Infarction (TIMI) risk scores in patients with NSTE-ACS...
2016: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/27912733/the-effect-of-percutaneous-coronary-intervention-on-habitual-physical-activity-in-older-patients
#2
Sarah J Charman, Vincent T van Hees, Louise Quinn, Joseph R Dunford, Bilal Bawamia, Murugapathy Veerasamy, Michael I Trenell, Djordje G Jakovljevic, Vijay Kunadian
BACKGROUND: Given the ongoing burden of cardiovascular disease and an ageing population, physical activity in patients with coronary artery disease needs to be emphasized. This study assessed whether sedentary behaviour and physical activity levels differed among older patients (≥75 years) following percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) consisting of ST-segment elevation myocardial infarction (STEMI) and non STEMI (NSTEMI) versus an elective admission control group of stable angina patients...
December 3, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27899940/staged-versus-one-time-multivessel-intervention-in-elderly-patients-with-non-st-elevation-acute-coronary-syndrome
#3
Xiao-Fan Yu, Yi Li, Qian-Cheng Wang, Xiao-Zeng Wang, Ming Liang, Xin Zhao, Kai Xu, Ya-Ling Han
OBJECTIVE: To evaluate the clinical outcomes of "one-time" versus staged multivessel stenting in elderly (≥ 60 years) patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) and multivessel disease (MVD). METHODS: We analyzed data of consecutive NSTE-ACS patients with multivessel percutaneous coronary intervention (PCI) who were enrolled in General Hospital of Shenyang Military Region between 2008 and 2012. A total of 1090 eligible patients aged ≥ 60 were further categorized into "one-time" group (n = 623) and staged PCI group (n = 467) according to intervention strategy...
September 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27899069/gastric-dilatation-and-intestinal-obstruction-mimicking-acute-coronary-syndrome-with-dynamic-electrocardiographic-changes
#4
H M M T B Herath, Anne Thushara Matthias, B S D P Keragala, W A E Udeshika, Aruna Kulatunga
BACKGROUND: ST elevation myocardial infarction is a medical emergency and the electrocardiogram is a part of the mainstay in the initial diagnosis. A variety of non-cardiac conditions have been known to mimic the electrocardiographic changes seen in acute coronary syndrome. We present a patient presenting with acute partial intestinal obstruction causing gastric distension and intestinal dilatation who also had dynamic electrocardiographic changes, mimicking anterior ST elevation myocardial infarction...
November 29, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27895696/efficacy-of-danlou-tablet-in-patients-with-non-st-elevation-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention-results-from-a-multicentre-placebo-controlled-randomized-trial
#5
Lei Wang, Xujie Zhao, Shuai Mao, Shaonan Liu, Xinfeng Guo, Liheng Guo, Tinghai Du, Haiyu Yang, Fuhai Zhao, Keng Wu, Hongliang Cong, Yang Wu, Phillip C Yang, Keji Chen, Minzhou Zhang
This study seeks to investigate potential cardioprotection of Danlou Tablets in patients undergoing PCI with non-ST elevation acute coronary syndrome (NSTE-ACS). 219 patients with NSTE-ACS were randomised to Danlou Tablet pretreatment (n = 109) or placebo (n = 110). No patients received statins prior to PCI and all patients were given atorvastatin (10 mg/day) after procedure. The main endpoint was the composite incidence of major adverse cardiac events (MACEs) within 30 days after PCI. The proportion of patients with elevated levels of cTn I>5 × 99% of upper reference limit was significantly lower in the Danlou Tablet group at 8 h (22...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27894787/safety-and-efficacy-of-liraglutide-treatment-in-japanese-type-2-diabetes-patients-after-acute-myocardial-infarction-a-non-randomized-interventional-pilot-trial
#6
Masataka Kajiwara, Atsushi Tanaka, Tomohiro Kawasaki, Koichi Nakao, Tomohiro Sakamoto, Shigeru Toyoda, Teruo Inoue, Nobuhiko Koga, Koichi Node
BACKGROUND: Glucagon-like peptide 1 analogs are expected to exert a cardio-protective action due to their effective glucose-lowering action and favorable potency on multifactorial metabolic pathways. However, the safety and tolerability of liraglutide treatment after a recent acute coronary syndrome (ACS) in Japanese patients with type 2 diabetes mellitus (T2DM) have yet to be fully established. METHODS: A total of eight T2DM patients were recruited within 2 weeks after the onset of a ST-elevation myocardial infarction (STEMI) followed by successful percutaneous coronary intervention (PCI)...
November 25, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27893054/outcomes-and-temporal-trends-of-inpatient-percutaneous-coronary-intervention-at-centers-with-and-without-on-site-cardiac-surgery-in-the-united-states
#7
Kashish Goel, Tanush Gupta, Dhaval Kolte, Sahil Khera, Gregg C Fonarow, Deepak L Bhatt, Mandeep Singh, Charanjit S Rihal
Importance: There are concerns whether percutaneous coronary intervention (PCI) at centers without on-site cardiac surgery is safe outside of a tightly regulated research environment. Objective: To analyze the outcomes and temporal trends of inpatient PCI at centers without on-site cardiac surgery in an unselected and nationally representative population of the United States. Design, Setting, and Participants: A national inpatient sample (N = 6 912 232) was used to identify patients who underwent inpatient PCI in the United States from January 1, 2003, to December 31, 2012...
November 23, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27889328/multiple-spontaneous-coronary-artery-dissections-an-uncommon-cause-of-acute-coronary-syndrome-in-a-syrian-refugee
#8
Tina Zhu, Peggy DeJong, Amer M Johri
Spontaneous coronary artery dissection is an uncommon nonatherosclerotic cause of acute coronary syndrome. It usually occurs in young women and is often associated with fibromuscular dysplasia, connective tissue diseases, and pregnancy or postpartum states. We present a case of a Syrian woman with a history of grand multiparity and recent miscarriage who presented with non-ST-elevation myocardial infarction and was found to have multivessel spontaneous coronary artery dissection and severe left ventricular dysfunction...
August 24, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27884352/timing-of-coronary-invasive-strategy-in%C3%A2-non-st-segment-elevation-acute-coronary-syndromes-and-clinical-outcomes-an-updated-meta-analysis
#9
Laurent Bonello, Marc Laine, Etienne Puymirat, Gilles Lemesle, Franck Thuny, Franck Paganelli, Pierre Michelet, Antoine Roch, François Kerbaul, Laurent Boyer
OBJECTIVES: The aim of this study was to compare an early versus a delayed invasive strategy in non-ST-segment elevation acute coronary syndromes by performing a meta-analysis of all available randomized controlled clinical trials. BACKGROUND: An invasive approach is recommended to prevent death and myocardial infarction in non-ST-segment elevation acute coronary syndromes. However, the timing of angiography and the subsequent intervention, when required, remains controversial...
November 28, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27869899/-patients-with-non-st-elevation-acute-coronary-syndrome-managed-without-coronary-revascularization-an-undertreated-population
#10
Alberto Menozzi, Leonardo De Luca, Zoran Olivari, Roberta Rossini, Marco Ferlini, Daniela Lina, Maurizio Giuseppe Abrignani, Piera Capranzano, Nazario Carrabba, Marcello Galvani, Alfredo Marchese, Gianfranco Mazzotta, Luciano Moretti, Nicola Signore, Massimo Uguccioni, Stefano De Servi
Non-ST-elevation acute coronary syndromes (NSTE-ACS) represent one of the most common clinical presentations of ischemic heart disease. Patients with NSTE-ACS are a heterogeneous population, with different clinical features and prognosis. A significant proportion of this population is medically managed, without any revascularization. In the Italian EYESHOT and French FAST-MI registries, patients managed with a conservative strategy were 40% and 35%, respectively. NSTE-ACS patients not undergoing coronary revascularization are at higher risk of adverse cardiovascular events and have a worse prognosis, including short- and long-term mortality, compared with those receiving revascularization...
October 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/27861369/the-relationship-between-heart-rate-and-mortality-of-patients-with-acute-coronary-syndromes-in-the-coronary-intervention-era-meta-analysis
#11
Tan Xu, Youqin Zhan, Jianping Xiong, Nan Lu, Zhuoqiao He, Xi Su, Xuerui Tan
BACKGROUND: Most of acute coronary syndromes (ACS) were receiving intervention treatment a high overall rate of coronary angiography in the modern medical practice.Consequently, we conduct a review to determine the heart rate (HR) on the prognosis of ACS in the coronary intervention era. METHODS: PubMed, EMBASE, MEDLINE, and the Cochrane Library was systematically searched up to May 2016 using the search terms "heart rate," "acute coronary syndrome," "acute myocardial infarction," "ST elevation myocardial infarction," "non-ST-segment elevation...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27852588/relationship-between-%C3%AE-blocker-therapy-at-discharge-and-clinical-outcomes-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#12
Chenze Li, Yang Sun, Xiaoqing Shen, Ting Yu, Qing Li, Guoran Ruan, Lina Zhang, Qiang Huang, Hang Zhuang, Jingqiu Huang, Li Ni, Luyun Wang, Jiangang Jiang, Yan Wang, Dao Wen Wang
BACKGROUND: The evidence supporting the use of β-blockers in patients with acute coronary syndrome after successful percutaneous coronary intervention has been inconsistent and scarce. METHODS AND RESULTS: Between March 1, 2009, and December 30, 2014, a total of 3180 eligible patients with acute coronary syndrome undergoing percutaneous coronary intervention were consecutively enrolled. The primary end point was all-cause death and the secondary end point was a composite of all-cause death, nonfatal myocardial infarction, heart failure readmission, and cardiogenic hospitalization...
November 16, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27849262/time-to-treatment-of-acute-coronary-syndrome-and-unit-of-first-contact-in-the-erico-study
#13
Rafael Caire de Oliveira Dos Santos, Alessandra Carvalho Goulart, Alan Loureiro Xavier Kisukuri, Rodrigo Martins Brandão, Debora Sitnik, Henrique Lane Staniak, Marcio Sommer Bittencourt, Paulo Andrade Lotufo, Isabela Martins Bensenor, Itamar de Souza Santos
BACKGROUND: To the best of our knowledge, there are no studies evaluating the influence of the unit of the first contact on the frequency and time of pharmacological treatment during an acute coronary syndrome (ACS) event. OBJECTIVES: The main objective was to investigate if the unit of first contact influenced the frequency and time of aspirin treatment in the Strategy of Registry of Acute Coronary Syndrome (ERICO) study. METHODS: We analyzed the pharmacological treatment time in 830 ERICO participants - 700 individuals for whom the hospital was the unit of first contact and 130 who initially sought primary care units...
October 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27847338/a-chinese-patent-medicine-shexiang-baoxin-pill-for-non-st-elevation-acute-coronary-syndromes-a-systematic-review
#14
Zhou Zhou, Weixing Shen, Lili Yu, Cong Xu, Qibiao Wu
ETHNOPHARMACOLOGICAL RELEVANCE: Shexiang Baoxin Pill (SXBXP) is a well-known Chinese patent medicine, widely used for Non-ST-elevation acute coronary syndromes (NSTE-ACS). It is composed of seven materia medicas or extracts (Moschus, Radix Ginseng, Calculus Bovis, Cortex Cinnamomi, Styrax, Venenum Bufonis and Borneolum Syntheticum). AIM OF THE STUDY: This study is aimed to systematically review the relevant randomised controlled trials (RCTs) to determine the efficacy and safety of SXBXP for long-term management of NSTE-ACS...
November 12, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27846735/perioperative-management-of-dual-anti-platelet-therapy
#15
Tyler D Webster, Prashant Vaishnava, Kim A Eagle
Dual anti-platelet therapy denotes a regimen of aspirin plus a P2Y12 receptor inhibitor, clopidogrel, prasugrel, or ticagrelor. Such therapy is a cornerstone of medical management following acute coronary syndromes and is imperative following percutaneous coronary interventions. While there is uncertainty about the optimal duration of dual antiplatelet therapy following percutaneous coronary intervention, the new 2016 American College of Cardiology/American Heart Association Guidelines suggest that for patients with stable ischemic heart disease at least six months of such therapy following a drug eluting stent and one month following a bare metal stent should be implemented...
December 4, 2016: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/27836168/the-olson-method-for-detection-of-acute-myocardial-ischemia-in-patients-with-coronary-occlusion
#16
Thomas Lindow, Charles W Olson, Cees A Swenne, Sumche Man, Olle Pahlm
: An automated ECG-based method may provide diagnostic support in the management of patients with acute coronary syndrome. The Olson method has previously proved to accurately identify the culprit artery in patients with acute coronary occlusion. METHODS: The Olson method was applied to 360 patients without acute myocardial ischemia and 52 patients with acute coronary occlusion. RESULTS: This study establishes the normal variation of the Olson wall scores in patients without acute myocardial ischemia, which provides the basis for implementation of the Olson method for triage of patients with acute coronary syndrome...
October 19, 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27832202/helicobacter-pylori-seropositivity-in-patients-with-interleukin-1-polymorphisms-is-significantly-associated-with-st-segment-elevation-myocardial-infarction
#17
Noriaki Tabata, Daisuke Sueta, Tomonori Akasaka, Yuichiro Arima, Kenji Sakamoto, Eiichiro Yamamoto, Yasuhiro Izumiya, Megumi Yamamuro, Kenichi Tsujita, Sunao Kojima, Koichi Kaikita, Kazunori Morita, Kentaro Oniki, Junji Saruwatari, Kazuko Nakagawa, Seiji Hokimoto
BACKGROUND: Helicobacter pylori infection and interleukin-1 polymorphisms are associated with an increased risk of gastric cancer. We examined the prevalence of Helicobacter pylori seropositivity and interleukin-1 polymorphisms between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome patients. METHODS: We recruited consecutive acute coronary syndrome patients, and 101 non-ST-segment elevation acute coronary syndrome patients and 103 ST-segment elevation myocardial infarction patients were enrolled...
2016: PloS One
https://www.readbyqxmd.com/read/27831644/study-on-the-levels-of-uric-acid-and-high-sensitivity-c-reactive-protein-in-acs-patients-and-their-relationships-with-the-extent-of-the-coronary-artery-lesion
#18
Q-Q Ma, X-J Yang, N-Q Yang, L Liu, X-D Li, K Zhu, Q Fu, P Wei
OBJECTIVE: We evaluated uric acid (UA) and high-sensitivity C-reactive protein (hs-CRP) levels in different clinical types of acute coronary syndromes (ACS) and in relationship with the severity of coronary artery lesions. Furthermore, we explored its clinical significance. PATIENTS AND METHODS: From June 2013 to January 2015, we studied patients in their first onset of symptoms and hospitalization for coronary angiography. According to coronary angiography results, we divided patients into two groups: 93 patients with ACS and 30 patients with normal coronary arteries as the control group...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27826657/st-segment-category-at-acute-presentation-is-associated-with-the-time-course-of-coronary-artery-disease-progression-in-patients-with-acute-coronary-syndromes
#19
Tatsuya Nakachi, Masami Kosuge, Naoki Iinuma, Hidekuni Kirigaya, Shingo Kato, Kazuki Fukui, Kazuo Kimura
BACKGROUND: Several studies have shown higher early mortality for ST-segment elevation acute coronary syndrome (STEACS), but late mortality remains consistently higher for non-ST-segment elevation acute coronary syndrome (NSTEACS). We hypothesized that ST-segment category at acute presentation is associated with the time course of coronary artery disease progression (CP) of nonculprit lesions in patients with acute coronary syndrome (ACS). METHODS: A total of 226 patients (182 men, age 65 ± 10 years) with STEACS (n = 95) or NSTEACS (n = 131) who underwent percutaneous coronary intervention (PCI) during initial hospitalization were studied...
November 8, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27826335/-one-time-versus-staged-multivessel-intervention-in-intermediate-to-very-high-risk-patients-with-non-st-segment-elevation-acute-coronary-syndromes
#20
Xiaofan Yu, Yi Li, Qiancheng Wang, Ming Liang, Kai Xu, Yaling Han
BACKGROUND AND OBJECTIVES: To compare clinical outcomes of staged versus "one-time" percutaneous coronary intervention (PCI) in intermediate to very high-risk patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) and multivessel coronary disease (MVD). SUBJECTS AND METHODS: 1531 NSTE-ACS patients with multivessel PCI and meeting the criteria of intermediate to very high risk were screened from a prospectively registered database obtained from General Hospital of Shenyang Military Region between 2008 and 2012...
November 2016: Korean Circulation Journal
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