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https://www.readbyqxmd.com/read/29336125/association-of-chronic-subjective-tinnitus-with-neuro-cognitive-performance
#1
Sunita Gudwani, Sanjay K Munjal, Naresh K Panda, Adarsh Kohli
INTRODUCTION: Chronic subjective tinnitus is associated with cognitive disruptions affecting perception, thinking, language, reasoning, problem solving, memory, visual tasks (reading) and attention. OBJECTIVE: To evaluate existence of any association between tinnitus parameters and neuropsychological performance to explain cognitive processing. MATERIALS AND METHODS: Study design was prospective, consisting 25 patients with idiopathic chronic subjective tinnitus and gave informed consent before planning their treatment...
December 1, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/29314412/coping-thought-suppression-and-perceived-stress-in-currently-depressed-previously-depressed-and-never-depressed-individuals
#2
Jens C Thimm, Catharina E A Wang, Knut Waterloo, Martin Eisemann, Marianne Halvorsen
BACKGROUND: Previous research shows that depression is associated with an increase in stressful life events and perceived stress as well as dysfunctional ways of coping with stress. However, knowledge about coping in previously depressed individuals is scant. METHODS: This study compared perceived stress, coping, and thought suppression in a sample of 30 currently depressed, 63 previously depressed, and 42 never depressed individuals. RESULTS: Analysis of variance revealed that previously depressed individuals showed less wishful thinking and thought suppression than the currently depressed individuals, but scored significantly higher on these strategies than the never depressed individuals...
January 4, 2018: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/29312526/amyotrophic-lateral-sclerosis-as-a-protein-level-non-genomic-disease-therapy-with-s2rm-exosome-released-molecules
#3
REVIEW
Greg Maguire
Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease that leads to death. No effective treatments are currently available. Based on data from epidemiological, etiological, laboratory, and clinical studies, I offer a new way of thinking about ALS and its treatment. This paper describes a host of extrinsic factors, including the exposome, that disrupt the extracellular matrix and protein function such that a spreading, prion-like disease leads to neurodegeneration in the motor tracts...
November 26, 2017: World Journal of Stem Cells
https://www.readbyqxmd.com/read/29231139/catechol-o-methyltransferase-cognition-and-alzheimer-s-disease
#4
Matea Nikolac Perkovic, Dubravka Svob Strac, Lucija Tudor, Marcela Konjevod, Gordana Nedic Erjavec, Nela Pivac
OBJECTIVE: Cognition is a complex trait representing a set of all mental abilities and processes related to knowledge. Although diverse brain regions are involved, most cognitive processes appear to engage cortical regions. The activity of dopaminergic neurons in prefrontal cortex represents a biological substrate underlying cognitive functions. Alzheimer's disease (AD) is the most frequent dementia associated with cognitive impairments. Cognitive impairment in AD starts slow with discrete deterioration in memory, language, thinking and reasoning, but it progresses into more severe and debilitating cognitive dysfunction...
December 11, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/29227799/cognitive-function-after-status-epilepticus-versus-after-multiple-generalized-tonic-clonic-seizures
#5
Kjersti N Power, Arne Gramstad, Nils Erik Gilhus, Karl Ove Hufthammer, Bernt A Engelsen
OBJECTIVES: Status epilepticus (SE) is considered a risk for cognitive impairment. Studies have indicated that SE cause more cognitive decline than multiple lifetime generalized tonic clonic (GTC) seizures. The aim of the study was to investigate whether patients suffering from SE or from multiple lifetime GTC seizures have cognitive dysfunction, and if the disabilities differ between these groups. MATERIALS AND METHODS: Patients suffering from SE were evaluated shortly after the clinical post-ictal phase and again after one year...
November 28, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29201378/time-to-re-think-the-use-of-dobutamine-in-sepsis
#6
Ryota Sato, Michitaka Nasu
Dobutamine is commonly used worldwide and included in the protocol for early goal-directed therapy (EGDT). Since the use of dobutamine in EGDT was reported, it has been considered to be an important component, especially in the treatment of septic patients with myocardial dysfunction. However, it is questionable whether dobutamine improves the mortality of sepsis and septic shock. In three recent randomized controlled trials (ProCESS, ProMISe, and ARISE trials), the frequency of dobutamine use was significantly higher in the EGDT group than in the standard care group, but there were no significant differences in the mortality between the groups...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/29181153/efficacy-of-alogliptin-combined-with-motor-imagery-under-hyperbaric-oxygen-in-diabetic-nephropathy-with-silent-cerebral-infarction
#7
Danyan Chen, Xiaolong Huang, Hua Gan, Xiaogang Du, Song Lu, Rongxi Huang, Ke Liu, Binghan Zhang
In the present study, we evaluated the curative effect of dipeptidyl peptidase-IV (DPP-IV) inhibitor alogliptin combined with motor imagery under hyperbaric oxygen in diabetic nephropathy (DN) with silent cerebral infarction (SCI). Two-hundred newly diagnosed DN patients with and without SCI were included. The SCI patients were divided into two treatment groups: Alogliptin (A group, n=50) and alogliptin combined with motor imagery under hyperbaric oxygen (B group, n=50). The degrees of neurocognitive dysfunction were evaluated at baseline and after 6 months of treatment...
November 2017: Biomedical Reports
https://www.readbyqxmd.com/read/29180795/hypertension-and-obesity-comorbidities-increases-coronary-risk-affects-domains-of-sexual-function-and-sexual-quality-of-life
#8
H Alidu, W K B A Owiredu, N Amidu, C K Gyasi-Sarpong, P P M Dapare, A T Bawah, C Obirikorang, A T Luuse
About 25% of the world's adult population suffers from arterial hypertension with about 1.5 billion estimated to develop hypertension by 2025. Hypertensive patients have been reported to have a higher risk of developing diabetes and sexual dysfunction. Hypertension have been linked with lubricative and orgasmic difficulties in females, as wel as ED and vascular disease in men. Obesity has also been linked to ED in diabetic males as well as several aspects of female sexuality. Hypertension and obesity are closely related, each occurring in greater frequency with the other, it is only logical to think that comorbidities of obesity and hypertension could increase the risk of cardiovascular disease and SD...
November 27, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29175518/social-cognitive-dysfunction-as-a-clinical-marker-a-systematic-review-of-meta-analyses-across-30-clinical-conditions
#9
REVIEW
Jack Cotter, Kiri Granger, Rosa Backx, Matthew Hobbs, Chung Yen Looi, Jennifer H Barnett
Social cognition includes a range of cognitive processes that help individuals to understand how others think and feel. There is emerging evidence that social cognitive deficits may represent a transdiagnostic issue, potentially serving as a marker of neurological abnormality. We performed an electronic database search in order to identify published, peer-reviewed meta-analyses that compared facial emotion recognition or theory of mind task performance between individuals meeting clinical criteria for a psychiatric, neurological or developmental condition against healthy controls...
January 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29122592/new-perspectives-on-the-brain-lesion-approach-implications-for-theoretical-models-of-human-memory
#10
Muireann Irish, Marlieke T R van Kesteren
Human lesion studies represent the cornerstone of modern day neuropsychology and provide an important adjunct to functional neuroimaging methods. The study of human lesion groups with damage to distinct regions of the brain permits the identification of underlying mechanisms and structures not only associated with, but essential for, complex cognitive processes. Here, we consider a recent review by McCormick et al. in which the power of the lesion model approach is elegantly presented with respect to a host of sophisticated cognitive endeavors, including autobiographical memory, future thinking, spatial navigation, and decision-making...
November 6, 2017: Neuroscience
https://www.readbyqxmd.com/read/29117509/heart-rate-variability-mediates-the-link-between-rumination-and-depressive-symptoms-a-longitudinal-study
#11
Luca Carnevali, Julian F Thayer, Jos F Brosschot, Cristina Ottaviani
Ruminative thinking about negative feelings has been prospectively associated with increases in depressive symptoms and heightened risk for new onsets of major depression. One putative pathophysiological mechanism underlying this link might be represented by autonomic nervous system dysfunction. The objective of this longitudinal study was to evaluate the interplay between rumination, autonomic function (as revealed by heart rate variability (HRV) analysis), and depressive symptoms in healthy young subjects, over a three-year period...
November 5, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29110306/coping-strategies-and-perceived-social-support-in-fibromyalgia-syndrome-relationship-with-alexithymia
#12
Marialaura Di Tella, Valentina Tesio, Ada Ghiggia, Annunziata Romeo, Fabrizio Colonna, Enrico Fusaro, Giuliano Carlo Geminiani, Maria Bruzzone, Riccardo Torta, Lorys Castelli
Fibromyalgia (FM) is a chronic pain syndrome characterized by high levels of psychological distress and alexithymia, a personality disposition affecting emotional self-awareness. The main aim of the present study was to investigate for the first time the relationship between alexithymia and coping strategies on the one hand, and alexithymia and perceived social support on the other, in a sample of FM patients. To reach this aim, 153 FM patients completed a battery of tests assessing coping strategies, perceived social support, alexithymia, psychological distress and pain intensity...
November 7, 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/29097867/dysphagia-thinking-outside-the-box
#13
REVIEW
Hamish Philpott, Mayur Garg, Dunya Tomic, Smrithya Balasubramanian, Rami Sweis
Dysphagia is a common symptom that is important to recognise and appropriately manage, given that causes include life threatening oesophageal neoplasia, oropharyngeal dysfunction, the risk of aspiration, as well as chronic disabling gastroesophageal reflux (GORD). The predominant causes of dysphagia varies between cohorts depending on the interplay between genetic predisposition and environmental risk factors, and is changing with time. Currently in white Caucasian societies adopting a western lifestyle, obesity is common and thus associated gastroesophageal reflux disease is increasingly diagnosed...
October 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29090640/listening-into-2030-workshop-an-experiment-in-envisioning-the-future-of-hearing-and-communication-science
#14
Simon Carlile, Gregory Ciccarelli, Jane Cockburn, Anna C Diedesch, Megan K Finnegan, Ervin Hafter, Simon Henin, Sridhar Kalluri, Alexander J E Kell, Erol J Ozmeral, Casey L Roark, Jessica E Sagers
Here we report the methods and output of a workshop examining possible futures of speech and hearing science out to 2030. Using a design thinking approach, a range of human-centered problems in communication were identified that could provide the motivation for a wide range of research. Nine main research programs were distilled and are summarized: (a) measuring brain and other physiological parameters, (b) auditory and multimodal displays of information, (c) auditory scene analysis, (d) enabling and understanding shared auditory virtual spaces, (e) holistic approaches to health management and hearing impairment, (f) universal access to evolving and individualized technologies, (g) biological intervention for hearing dysfunction, (h) understanding the psychosocial interactions with technology and other humans as mediated by technology, and (i) the impact of changing models of security and privacy...
January 2017: Trends in Hearing
https://www.readbyqxmd.com/read/29080248/insidious-the-relationship-patients-have-with-their-eating-disorders-and-its-impact-on-symptoms-duration-of-illness-and-self-image
#15
Emma Forsén Mantilla, David Clinton, Andreas Birgegård
OBJECTIVES: In published clinical and autobiographical accounts of eating disorders, patients often describe their disorder in personified ways, that is, relating to the disorder as if it were an entity, and treatment often involves techniques of externalization. By encouraging patients to think about their eating disorder as a relationship, this study aimed to examine how young female patients experience their eating disorder as acting towards them, how they react in response, and whether these interactions are associated with symptoms, illness duration, and self-image...
October 28, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29071701/-the-hypothalamus-in-huntington-s-disease
#16
REVIEW
E Bellosta-Diago, A Viloria-Alebesque, S Santos-Lasaosa, L J Lopez Del Val
INTRODUCTION: Disorders affecting sleep and the circadian rhythm, autonomic clinical signs and symptoms, and neuroendocrine alterations are frequent characteristics in Huntington's disease, some of which present in early stages of the disease. It is reasonable to think that some of these features could result from a hypothalamic dysfunction affecting the centre regulating sleep, metabolism and the autonomic nervous system. AIM: The study presents the evidence available to date that suggests the involvement of a hypothalamic disorder in Huntington's disease...
November 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/29068571/location-of-the-ischemic-focus-in-rehabilitated-stroke-patients-with-impairment-of-executive-functions
#17
Agnieszka M Jankowska, Robert Klimkiewicz, Anna Kubsik, Paulina Klimkiewicz, Janusz Śmigielski, Marta Woldańska-Okońska
BACKGROUND: Executive dysfunctions are part of the clinical symptoms of a stroke and can inhibit the process of rehabilitation. Patients with impaired executive functions may manifest aggression, impulsiveness, impaired thinking and planning. OBJECTIVES: The aim of this study was to assess the effect of the ischemic focus location on the effectiveness of physiotherapy in improving the executive functions in patients after stroke. MATERIAL AND METHODS: Ninety patients after unilateral ischemic cerebral stroke were studied...
August 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29050193/-the-vessel-and-primary-glaucoma
#18
R S Li, Y Z Pan
Glaucoma, as the first leading cause of irreversible blindness in the world, is a chronic progressive optic neuropathy. The pathogenesis of glaucoma is still not fully understood till now. A lot of studies about vascular diameter, tortuosity, location, disc perfusion, vascular regulation and systemic vascular factors had been conducted to investigate the relationship between the vascular states and glaucoma since vascular hypothesis proposed. However, direct and convincing evidence for primary mechanisms of glaucoma is still lacking...
October 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29040091/preoperative-cognitive-dysfunction-it-s-more-common-than-you-think
#19
Jonathan P Wanderer, James P Rathmell
No abstract text is available yet for this article.
November 2017: Anesthesiology
https://www.readbyqxmd.com/read/29033974/cognitive-deficits-in-chronic-stroke-patients-neuropsychological-assessment-depression-and-self-reports
#20
Arne E Nakling, Dag Aarsland, Halvor Næss, Daniel Wollschlaeger, Tormod Fladby, Håkon Hofstad, Eike Wehling
BACKGROUND: Following stroke, clinicians are challenged to detect and untangle symptoms of cognitive dysfunction and mood disorders. Additionally, they need to evaluate the informative value of self-reports to identify patients in need of further attendance. AIMS: To examine the association between neuropsychological measures, symptoms of depression, and self-reported cognitive function. METHODS: One-hundred and five chronic stroke patients underwent assessment covering 6 cognitive domains and answered the Hospital Anxiety and Depression Scale and the Memory and Thinking Scale from the Stroke Impact Scale 1 year after stroke...
May 2017: Dementia and Geriatric Cognitive Disorders Extra
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