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electrocardiography sleep apnea

Carmen Pizarro, Fabian van Essen, Fabian Linnhoff, Robert Schueler, Christoph Hammerstingl, Georg Nickenig, Dirk Skowasch, Marcel Weber
BACKGROUND: COPD and congestive heart failure represent two disease entities of growing global burden that share common etiological features. Therefore, we aimed to identify the degree of left ventricular (LV) dysfunction in COPD as a function of COPD severity stages and concurrently placed particular emphasis on the presence of overlapping obstructive sleep apnea (OSA). METHODS: A total of 85 COPD outpatients (64.1±10.4 years, 54.1% males) and 20 controls, matched for age, sex, and smoking habits, underwent speckle tracking echocardiography for LV longitudinal strain imaging...
2016: International Journal of Chronic Obstructive Pulmonary Disease
Tsogyal Daniela Latshang, Barbara Kaufmann, Yvonne Nussbaumer-Ochsner, Silvia Ulrich, Michael Furian, Malcolm Kohler, Robert Thurnheer, Ardan Muammer Saguner, Firat Duru, Konrad Ernst Bloch
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) promotes myocardial electrical instability and may predispose to nocturnal sudden cardiac death. We evaluated whether hypobaric hypoxia during altitude travel further impairs cardiac repolarization in patients with OSA, and whether this is prevented by acetazolamide, a drug known to improve oxygenation and central sleep apnea at altitude. METHODS: Thirty-nine OSA patients living < 600 m, discontinued continuous positive airway pressure therapy during studies at 490 m and during two sojourns of 3 days at altitude (2 days at 1860 m, 1 day at 2590 m)...
2016: Sleep
Xuehao Gong, Leidan Huang, Xin Liu, Chunyue Li, Xuhua Mao, Weizong Liu, Xian Huang, Haiting Chu, Yumei Wang, Wanqing Wu, Jun Lu
Heart rate variability (HRV) can reflect the changes in the autonomic nervous system (ANS) that are affected by apnea or hypopnea events among patients with obstructive sleep apnea hypopnea syndrome (OSAHS). To evaluate the possibility of using HRV to screen for OSAHS, we investigated the relationship between HRV and polysomnography (PSG) diagnostic indices using electrocardiography (ECG) and PSG data from 25 patients with OSAHS and 27 healthy participants. We evaluated the relationship between various PSG diagnostic indices (including the apnea hypopnea index [AHI], micro-arousal index [MI], oxygen desaturation index [ODI]) and heart rate variability (HRV) parameters using Spearman's correlation analysis...
2016: PloS One
Flávia B Nerbass, Vera M C Salemi, Rodrigo P Pedrosa, Natanael de P Portilho, Julio C A Ferreira-Filho, Henrique T Moriya, Murillo O Antunes, Edmundo Arteaga-Fernández, Luciano F Drager, Geraldo Lorenzi-Filho
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a common genetic disease that may cause left ventricular outflow tract (LVOT) obstruction, heart failure, and sudden death. Recent studies have shown a high prevalence of obstructive sleep apnea among patients with HCM. Because the hemodynamics of patients with LVOT obstruction are unstable and depend on load conditions to the heart, we evaluated the acute effects of CPAP on hemodynamics and cardiac performance in patients with HCM. METHODS: We studied 26 stable patients with HCM divided into nonobstructive-HCM (n=12) and obstructive-HCM (n=14) groups (LVOT gradient pressure lower or higher than 30 mm Hg, respectively)...
May 7, 2016: Chest
Thomas Gaisl, Annette M Wons, Valentina Rossi, Daniel J Bratton, Christian Schlatzer, Esther I Schwarz, Giovanni Camen, Malcolm Kohler
BACKGROUND: A high P-wave duration and dispersion (Pd) have been reported to be a prognostic factor for the occurrence of paroxysmal atrial fibrillation (PAF), a condition linked to obstructive sleep apnea (OSA). We tested the hypothesis of whether a short-term increase of P-wave duration and Pd can be induced by respiratory manoeuvres simulating OSA in healthy subjects and in patients with PAF. METHODS: 12-lead-electrocardiography (ECG) was recorded continuously in 24 healthy subjects and 33 patients with PAF, while simulating obstructive apnea (Mueller manoeuvre, MM), obstructive hypopnea (inspiration through a threshold load, ITH), central apnea (AP), and during normal breathing (BL) in randomized order...
2016: PloS One
Ren-Jing Huang, Ching-Hsiang Lai, Shin-Da Lee, Wei-Che Wang, Ling-Hui Tseng, Yu-Pin Chen, Shen-Wen Chang, Ai-Hui Chung, Hua Ting
PURPOSE: To assess the physiological meanings of the detrended fluctuation analysis (DFA) slope α and its relationship to spectral measures in heart rate variability, this study investigated changes of α and its corresponding spectral measures over various night-sleep stages. METHODS: The overall DFA α and natural-logarithm-transformed power values of the spectral parameters ln[high-frequency (HF)], ln[low-frequency (LF)], and ln[very-low-frequency (VLF)], and their relationship from one 5-min proper electrocardiography segment in each of pre-sleep-wakefulness (AWK), non-rapid eye movement stage 2 (N2), slow-wave (N3), the first and the latest rapid-eye movement sleep (REM1, and REM2), were computed in 93 otherwise healthy males (44...
September 2016: Sleep & Breathing, Schlaf & Atmung
Younghoon Kwon, Katherine Picel, Selcuk Adabag, Tien Vo, Brent C Taylor, Susan Redline, Katie Stone, Reena Mehra, Sonia Ancoli-Israel, Kristine E Ensrud
PURPOSE: Nocturnal cardiac conduction abnormalities are commonly observed in patients with sleep-disordered breathing (SDB). However, few population-based studies have examined the association between SDB and daytime cardiac conduction abnormalities. METHODS: We examined a random sample of 471 community-dwelling men, aged ≥67 years, enrolled in the multi-center Outcomes of Sleep Disorders in Older Men (MrOS Sleep) study. SDB severity was categorized using percent of total sleep time with oxygen saturation <90 % (%TST < 90) and apnea hypopnea index (AHI)...
March 12, 2016: Sleep & Breathing, Schlaf & Atmung
Muntecep Asker, Selvi Asker
BACKGROUND AND AIM OF THE STUDY: It was hypothesized that sleep disorders might be present due to functional heart failure in patients with mitral stenosis (MS), and might be accompanied by obstructive-type sleep disorders. To examine this hypothesis, non-smoker and non-obese patients with rheumatic MS and without concomitant diseases were investigated for sleep disorders. METHODS: Patients admitted to the cardiology outpatient clinic at the authors' institution for rheumatic MS during a one-year period were included in the study...
May 2015: Journal of Heart Valve Disease
Shicheng Su, Ning Ding, Xianji Zhu, Xilong Zhang, Rongbin Yu
OBJECTIVE: To evaluate the occurrence and clinical characteristics of sleep apnea syndrome (SAS) in heart failure (HF) patients with atrial fibrillation (AF). METHODS: From HF patients hospitalized in the First Affiliated Hospital of Nanjing Medical University during June 2012 and June 2014, subjects were recruited based on electrocardiography examination, including 110 patients with AF (coexisting AF group) and 105 parallel control patients without AF but with matched age, gender and body mass index (simple HF group)...
October 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Ruth Sanchez-Ortiga, Vicente Climent, Laura Sanchez-Tejada, Alfredo Candela, Antonio Pico
OBJECTIVE: To assess whether sleep apnea-hypopnea syndrome (SAHS) is a risk factor for development of acromegalic cardiomyopathy. METHODS: A descriptive, cross-sectional study of 32 patients with acromegaly (15 categorized as non-controlled-NCA and 17 as controlled-CA) compared to 20 matched controls (by sex, age, and BMI) referred to the pulmonology department for suspected SAHS. Polysomnography, echocardiography (M-mode, 2-dimensional, and Doppler), and 12-lead electrocardiography were performed in all participants...
October 2015: Endocrinología y Nutrición: órgano de la Sociedad Española de Endocrinología y Nutrición
Abu S Shamsuzzaman, Virend K Somers, Timothy K Knilans, Michael J Ackerman, Yu Wang, Raouf S Amin
BACKGROUND: Congenital long QT syndrome (LQTS) is a familial arrhythmogenic cardiac channelopathy characterized by prolonged ventricular repolarization and increased risk of torsades de pointes-mediated syncope, seizures, and sudden cardiac death (SCD). QT prolongation corrected for heart rate (QTc) is an important diagnostic and prognostic feature in LQTS. Obstructive sleep apnea (OSA) has been increasingly implicated in the pathogenesis of cardiovascular disease, including arrhythmias and SCD...
2015: Sleep
Adem Adar, Abdulkadir Kırış, Yılmaz Bülbül, Hüseyin Bektaş, Murat Acat, Hasan Casim, Orhan Onalan
OBJECTIVE: We aimed to investigate whether fragmented QRS (fQRS) is associated with subclinical left ventricular (LV) dysfunction in patients with obstructive sleep apnea (OSA). SUBJECTS AND METHODS: A total of 141 patients with OSA who had normal LV ejection fraction (LVEF) were included in the study. The fQRS was defined as the presence of an additional R wave, notching of R or S wave or the presence of fragmentation in 2 contiguous electrocardiography (ECG) leads...
2015: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
Haitham Ezzat, Amr Mohab
Sleep disorders are common among the patients undergoing dialysis in end stage renal disease (ESRD). Although variable, their prevalence has been reported to be higher when compared to the general population. The most frequently reported complaints are insomnia, restless leg syndrome (RLS), sleep-disordered breathing and excessive daytime sleepiness (EDS). The aim of this study was to assess the prevalence of sleep disorders in end stage renal disease patients on regular hemodialysis (group I with 30 patients) and CKD patients (group II with 30 patients) in comparison to 30 normal population (control group)...
July 2015: Renal Failure
Eduardo Luiz Pereira da Silva, Rafael Pereira, Luciano Neves Reis, Valter Luis Pereira, Luciana Aparecida Campos, Niels Wessel, Ovidiu Constantin Baltatu
In the present study, we aimed at investigating a heart rate variability (HRV) biomarker that could be associated with the severity of the apnea-hypopnea index (AHI), which could be used for an early diagnosis of obstructive sleep apnea (OSA). This was a cross-sectional observational study on 47 patients (age 36 ± 9.2 standard deviation) diagnosed with mild (23.4%), moderate (34%), or severe (42.6%) OSA. HRV was studied by linear measures of fast Fourier transform, nonlinear Poincaré analysis, and detrended fluctuation analysis (DFA)—DFA α1 characterizes short-term fluctuations, DFA α2 characterizes long-term fluctuations...
January 2015: Medicine (Baltimore)
Aleksandra Grdinić, Zoran Stajić, Aleksandar G Grdinić, Zarko Vucinić, Violeta Randjelović Krstić, Dragan Drobnjak, Predrag Bogdanović, Predrag Djurić, Angelina Stevanović, Milanko Rakonjac, Stanko Petrović, Ognjen Gudelj, Radomir Matunović
BACKGROUND/AIM: A possible cause of malignant heart rhythm disorders is the syndrome of sleep apnea (periodic cessation of breathing during sleep longer than 10 seconds). Recent 24 h ECG software systems have the option of determination ECG apnea index (AI) based on the change in voltage of QRS complexes. The aim of the study was to determine the significance of AI evaluation in routine 24-hour Holter ECG on a group of 12 patients. METHODS: We presented a total of 12 consecutive patients with previously documented arrhythmias and the history of breathing disorders during night...
November 2014: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
Dmitry M Yaranov, Athanasios Smyrlis, Natalia Usatii, Amber Butler, Joann R Petrini, Jose Mendez, Mark K Warshofsky
Obstructive sleep apnea (OSA) is an independent risk factor for ischemic stroke that is not included in the usual cardioembolic risk assessments for patients with atrial fibrillation (AF). The aim of this study was to investigate the impact of OSA on stroke rate in patients with AF. Patients with AF and new diagnoses of OSA were identified from retrospective chart review. Those with histories of stroke at the time of the sleep study were excluded. The primary outcome was the incidence of stroke, determined by a physician investigator blinded to the results of polysomnography...
February 15, 2015: American Journal of Cardiology
Davran Cicek, Akif Serhat Balcioğlu, Hüseyin Lakadamyali, Haldun Müderrisoğlu
The objective of the study was to determine the effects of nasal continuous positive airway pressure (nCPAP) therapy on left ventricular (LV) function and electrocardiographic parameters in newly diagnosed moderate/severe obstructive sleep apnea (OSA) patients without cardiovascular comorbidities and medical treatments. We examined 44 patients who underwent overnight polysomnography together with 24-hour Holter electrocardiography, cardiopulmonary exercise testing including heart rate recovery at 1 minute (HRR-1), echocardiography, surface electrocardiography, and those who were diagnosed with moderate/severe OSA apnea--hypopnea index ≥ 15...
2015: International Heart Journal
A Brzecka, M Pawelec-Winiarz, A Teplicki, P Piesiak, R Jankowska
Heart rate variation (HRV) reflects the activity of the autonomic nervous system. The aim of the study was to analyze HRV in obstructive sleep apnea (OSA) and obesity hypoventilation (OH) patients to answer the question of whether chronic alveolar hypoventilation influences autonomic heart rate regulation. In 41 patients, diagnosed with either 'pure' OSA (n=23, apnea/hypopnea index--AHI: 43.8±18.0 PaCO2≤45 mmHg) or OH syndrome (n=18, AHI 58.7±38.0 PaCO2>46 mmHg), the HRV was analyzed, based on an 8 h ECG recording during sleep...
2015: Advances in Experimental Medicine and Biology
Vega Pradana Rachim, Gang Li, Wan-Young Chung
Sleep apnea is often diagnosed using an overnight sleep test called a polysomnography (PSG). Unfortunately, though it is the gold standard of sleep disorder diagnosis, a PSG is time consuming, inconvenient, and expensive. Many researchers have tried to ameliorate this problem by developing other reliable methods, such as using electrocardiography (ECG) as an observed signal source. Respiratory rate interval, ECG-derived respiration, and heart rate variability analysis have been studied recently as a means of detecting apnea events using ECG during normal sleep, but these methods have performance weaknesses...
2014: Bio-medical Materials and Engineering
Giovanna Sannino, Ivanoe De Falco, Giuseppe De Pietro
Detection and real time monitoring of obstructive sleep apnea (OSA) episodes are very important tasks in healthcare. To suitably face them, this paper proposes an easy-to-use, cheap mobile-based approach relying on three steps. First, single-channel ECG data from a patient are collected by a wearable sensor and are recorded on a mobile device. Second, the automatic extraction of knowledge about that patient takes place offline, and a set of IF…THEN rules containing heart-rate variability (HRV) parameters is achieved...
September 2014: IEEE Journal of Biomedical and Health Informatics
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