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hydrogen peroxide decontamination

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https://www.readbyqxmd.com/read/29143704/identification-of-clostridium-difficile-reservoirs-in-the-patient-environment-and-efficacy-of-aerial-hydrogen-peroxide-decontamination
#1
Samuel Yui, Shanom Ali, Monika Muzslay, Annette Jeanes, A Peter R Wilson
OBJECTIVE To identify, using a novel enhanced method of recovery, environmental sites where spores of Clostridium difficile persist despite cleaning and hydrogen peroxide aerial decontamination. DESIGN Cohort study. SETTING Tertiary referral center teaching hospital. METHODS In total, 16 sites representing high-frequency contact or difficult-to-clean surfaces in a single-isolation room or bed area in patient bed bays were sampled before and after terminal or hydrogen peroxide disinfection using a sponge swab...
November 16, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29102134/inactivation-of-cronobacter-malonaticus-cells-and-inhibition-of-its-biofilm-formation-exposed-to-hydrogen-peroxide-stress
#2
Yingwang Ye, Maofeng Zhang, Rui Jiao, Na Ling, Xiyan Zhang, Liaowang Tong, Haiyang Zeng, Jumei Zhang, Qingping Wu
Presence of Cronobacter malonaticus in powdered infant formula (PIF) poses a high risk to infant and public health. Cronobacter malonaticus has been widely distributed in food and food processing environments, and the true origin of C. malonaticus in PIF is poorly understood. Control and prevention of C. malonaticus is necessary for achieving microbial safety of PIF. However, little information about decontamination of C. malonaticus is available. In this study, effects of hydrogen peroxide on inactivation and morphological changes of C...
October 25, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29032094/bicarbonate-activated-hydrogen-peroxide-and-efficient-decontamination-of-toxic-sulfur-mustard-and-nerve-gas-simulants
#3
Sanping Zhao, Hailing Xi, Yanjun Zuo, Qi Wang, Zhicheng Wang, Zengyuan Yan
(13)C NMR spectra showed that peroxymonocarbonate (HCO4(-)) was generated in the NaHCO3-activated H2O2 solution and pH was a key factor in its production. A cycle for the bicarbonate anion was proposed as HCO3(-)→HCO3 → (CO2)2*→CO2(aq)→HCO4(-) (H2CO4)→HCO3(-) (HCO3) basing on the results of NMR, electron paramagnetic resonance, chemiluminescence analysis. In this cycle, (CO2)2* was the key intermediate and (CO2)2*→2CO2+hv was the rate controlling step. Thioanisole and paraoxon, the simulants of sulfur mustard gas and nerve gas, respectively, were efficiently decontaminated by the NaHCO3-activated H2O2 solution...
October 2, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29020663/characterization-and-application-of-azo-dye-e-n-phenyl-4-thiazole-2-yldiazenyl-aniline-pda-for-biomedical-sterilization
#4
Ozge Surucu, Serdar Abaci
Sterilization is the certain and absolute decontamination of microorganisms totally from all manner of alive and active species. Sterilization devices used in the sterilization processes are between laboratory and external patient application devices of biomedical device technology, and they are designed to remove equipments from germs. The application potential of hetarilazo indole based azo dyes in the biomedical sterilization are known and azo dyes come into prominence in this class because of simplicity of their synthesis and procurement of low-cost raw materials...
September 27, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28984881/polyoxometalate-based-gelating-networks-for-entrapment-and-catalytic-decontamination
#5
Kevin P Sullivan, Wade A Neiwert, Huadong Zeng, Anil K Mehta, Qiushi Yin, Daniel A Hillesheim, Skanda Vivek, Panchao Yin, Daniel L Collins-Wildman, Eric R Weeks, Tianbo Liu, Craig L Hill
We report the synthesis and characterization of a new class of organic/inorganic hybrid polymers composed of covalently-bound 1,3,5-benzenetricarboxamide linkers and anionic polyoxovanadate clusters with varying counter-cations. These materials form gels within seconds upon contact with polar aprotic organic liquids and catalyze the degradation of odorants and toxic molecules under mild conditions including aerobic oxidation of thiols, hydrogen peroxide-catalyzed oxidation of sulfides, and hydrolysis of organophosphate chemical warfare agent analogues...
October 6, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28952000/the-efficacy-and-sterilisation-of-human-decellularised-dermal-allografts-with-combinations-of-cupric-ions-and-hydrogen-peroxide
#6
S F Leow-Dyke, P Rooney, J N Kearney
Decellularised tissue allografts have been used in reconstructive surgical applications and transplantation for many years. Some of the current methods of sterilisation have a detrimental effect on the tissue graft structure and function. The anti-microbial activity of cupric ions and hydrogen peroxide (H2O2) are well known however their combined application is not currently utilised as a decontamination agent in the tissue banking world sector. The aim of this study was to determine the combined concentrations of copper chloride (CuCl2) and H2O2 that have the optimal bactericidal and sporicidal activity on decellularised (dCELL) human dermis...
September 26, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28939316/controlling-a-possible-outbreak-of-candida-auris-infection-lessons-learnt-from-multiple-interventions
#7
M Biswal, S M Rudramurthy, N Jain, A S Shamanth, D Sharma, K Jain, L N Yaddanapudi, A Chakrabarti
BACKGROUND: Multidrug-resistant Candida auris infection has been reported from five continents in recent years. The prevalence of C. auris invasive infection has been estimated at 5.3% for intensive-care-acquired candidaemia in India. The transmission of the organism between the patients and from environment to patients is rapid. AIM: To understand the intra-hospital dynamics of C. auris transmission and to determine the possible interventions to prevent its spread...
September 19, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28893449/successful-control-of-2-simultaneous-outbreaks-of-oxa-48-carbapenemase-producing-enterobacteriaceae-and-multidrug-resistant-acinetobacter-baumannii-in-an-intensive-care-unit
#8
A Robustillo-Rodela, V Pérez-Blanco, M A Espinel Ruiz, G Ruiz Carrascoso, J C Figueira Iglesias, D Abad Martín
BACKGROUND: This report describes a double outbreak of OXA-48-producing Enterobacteriaceae (OXA-48-PE) and multidrug-resistant Acinetobacter baumannii (MRAB) in an intensive care unit (ICU) and the effectiveness of measures implemented, including decontamination with vaporized hydrogen peroxide (VHP). METHODS: Affected patients were isolated in a confined area and cared for by dedicated personnel. Four percent chlorhexidine soap was used for patient daily hygiene...
September 8, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28872735/in-vitro-efficacy-of-disinfectants-utilised-for-skin-decolonisation-and-environmental-decontamination-during-a-hospital-outbreak-with-candida-auris
#9
Alireza Abdolrasouli, Darius Armstrong-James, Lisa Ryan, Silke Schelenz
Candida auris has caused nosocomial infections and transmissions within hospital settings. As little is known about the efficacy of skin and environmental decontamination products to kill C. auris, this study investigated the in vitro activity of chlorine, chlorhexidine, iodine povidone and vaporised hydrogen peroxide products against C. auris. H2 O2 vapour showed 96.6%-100% effective killing of C. auris. All isolates were inhibited by chlorhexidine gluconate concentrations at 0.125%-1.5% and for iodinated povidone at 0...
September 5, 2017: Mycoses
https://www.readbyqxmd.com/read/28754034/effect-of-cultivation-ph-on-the-surface-hydrophobicity-of-bacillus-subtilis-spores
#10
Elisabeth Eschlbeck, Simon A W Bauer, Ulrich Kulozik
Bacillus subtilis spores are often used as biological indicators (BI) to monitor decontamination processes with gaseous hydrogen peroxide. Results in practical inactivation validation tests, however, vary considerably with no available explanation so far. This study reports on the effect of cultivation pH on spore surface hydrophobicity. Surface hydrophobicity is suspected to have an impact on the decontamination of technical surfaces such as packaging material when gaseous, condensing hydrogen peroxide is applied...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28736948/evaluating-the-efficacy-of-hydrogen-peroxide-vapour-against-foot-and-mouth-disease-virus-within-a-bsl4-biosafety-facility
#11
B M Petit, F C Almeida, T R Uchiyama, F O C Lopes, K H Tino, J Chewins
An evaluation was made of the efficacy of 35% hydrogen peroxide vapour (HPV) against foot-and-mouth disease virus (FMDV) in a biosafety facility. Biological indicators (BIs) were produced using three serotypes of FMDV, all with a titre of ≥10(6) TCID50 per ml. Fifteen BIs of each serotype were distributed across five locations, throughout a 30-m(3) airlock chamber, producing a total of 45 BIs. Thirty-five percent HPV was generated and applied using a Bioquell vaporization module located in the centre of the chamber...
October 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28672227/pyrimethanil-degradation-by-photo-fenton-process-influence-of-iron-and-irradiance-level-on-treatment-cost
#12
A Cabrera Reina, S Miralles-Cuevas, J L Casas López, J A Sánchez Pérez
This study evaluates the combined effect of photo-catalyst concentration and irradiance level on photo-Fenton efficiency when this treatment is applied to industrial wastewater decontamination. Three levels of irradiance (18, 32 and 46W/m(2)) and three iron concentrations (8, 20 and 32mg/L) were selected and their influence over the process studied using a raceway pond reactor placed inside a solar box. For 8mg/L, it was found that there was a lack of catalyst to make use of all the available photons. For 20mg/L, the treatment always improved with irradiance indicating that the process was photo-limited...
December 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28651076/application-of-water-assisted-ultraviolet-light-in-combination-of-chlorine-and-hydrogen-peroxide-to-inactivate-salmonella-on-fresh-produce
#13
Shuanghuan Guo, Runze Huang, Haiqiang Chen
With the demand for fresh produce increases in recent decades, concerns for microbiological safety of fresh produce are also raised. To identify effective ultraviolet (UV) light treatment for fresh produce decontamination, we first determined the effect of three forms of UV treatment, dry UV (samples were treated by UV directly), wet UV (samples were dipped in water briefly and then exposed to UV), and water-assisted UV (samples were treated by UV while being immersed in agitated water) on inactivation of Salmonella inoculated on tomatoes and fresh-cut lettuce...
June 19, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28642746/virucidal-activity-of-fogged-chlorine-dioxide-and-hydrogen-peroxide-based-disinfectants-against-human-norovirus-and-its-surrogate-feline-calicivirus-on-hard-to-reach-surfaces
#14
Naim Montazeri, Clyde Manuel, Eric Moorman, Janak R Khatiwada, Leonard L Williams, Lee-Ann Jaykus
Human norovirus (NoV) is the leading cause of foodborne illnesses in the United States. Norovirus is shed in high numbers in the feces and vomitous of infected individuals. Contact surfaces contaminated with bodily fluids harboring infectious virus particles serve as vehicles for pathogen transmission. Environmental stability of NoV and its resistance to many conventional disinfectants necessitate effective inactivation strategies to control the spread of virus. We investigated the efficacy of two commercial disinfectants, hydrogen peroxide (7...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28610932/automatic-environmental-disinfection-with-hydrogen-peroxide-and-silver-ions-versus-manual-environmental-disinfection-with-sodium-hypochlorite-a-multicentre-randomized-before-and-after-trial
#15
D Mosci, G W Marmo, L Sciolino, C Zaccaro, R Antonellini, L Accogli, T Lazzarotto, M Mongardi, M P Landini
BACKGROUND: New technologies for automated disinfection have been developed, including the use of hydrogen peroxide atomized by specific equipment, with associated silver compounds. AIMS: To compare the effectiveness of an automated disinfection system with hydrogen peroxide <8% and silver ion versus a manual method with 0.5% sodium hypochlorite solution when evaluating the reduction of microbial mesophilic contamination and Clostridium difficile presence; and to evaluate the time required for both of these processes...
June 10, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28524724/antibacterial-effect-of-hydrogen-peroxide-titanium-dioxide-suspensions-in-the-decontamination-of-rough-titanium-surfaces
#16
David Wiedmer, Fernanda Cristina Petersen, Jessica Lönn-Stensrud, Hanna Tiainen
The chemical decontamination of infected dental implants is essential for the successful treatment of peri-implantitis. The aim of this study was to assess the antibacterial effect of a hydrogen peroxide-titanium dioxide (H2O2-TiO2) suspension against Staphylococcus epidermidis biofilms. Titanium (Ti) coins were inoculated with a bioluminescent S. epidermidis strain for 8 h and subsequently exposed to H2O2 with and without TiO2 nanoparticles or chlorhexidine (CHX). Bacterial regrowth, bacterial load and viability after decontamination were analyzed by continuous luminescence monitoring, live/dead staining and scanning electron microscopy...
July 2017: Biofouling
https://www.readbyqxmd.com/read/28512177/evaluation-of-novel-process-indicators-for-rapid-monitoring-of-hydrogen-peroxide-decontamination-processes
#17
N P McLeod, M Clifford, J M Sutton
Geobacillus stearothermophilus spores on stainless steel discs are routinely used as biological indicators for the validation of hydrogen peroxide bio-decontamination processes. Given ongoing concerns about the reliability and response time of biological indicators, we explored the potential for an enzyme-based approach to decontamination process evaluation. Thermostable adenylate kinase enzyme was coated onto a solid support and exposed to hydrogen peroxide vapour, in parallel with standard commercial 6-log biological indicators, during a series of vapour-phase hydrogen peroxide cycles in a flexible film isolator...
September 2017: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/28500989/pharmaceuticals-benzene-toluene-and-chlorobenzene-removal-from-contaminated-groundwater-by-combined-uv-h2o2-photo-oxidation-and-aeration
#18
Ondřej Lhotský, Eva Krákorová, Pavel Mašín, Radim Žebrák, Lucie Linhartová, Zdena Křesinová, Josef Kašlík, Jana Steinová, Torgeir Rødsand, Alena Filipová, Klára Petrů, Kristýna Kroupová, Tomáš Cajthaml
This study was performed to test the feasibility of several decontamination methods for remediating heavily contaminated groundwater in a real contaminated locality in the Czech Republic, where a pharmaceuticals plant has been in operation for more than 80 years. The site is polluted mainly by recalcitrant psychopharmaceuticals and monoaromatic hydrocarbons, such as benzene, toluene and chlorobenzene. For this purpose, an advanced oxidation technique employing UV radiation with hydrogen peroxide dosing was employed, in combination with simple aeration pretreatment...
September 1, 2017: Water Research
https://www.readbyqxmd.com/read/28482224/use-of-photo-fenton-s-reaction-by-400-nm-led-light-for-endodontic-disinfection-a-preliminary-in-vitro-study-on-enterococcus-faecalis
#19
Giuseppe Lagori, Carlo Fornaini, Jean-Paul Rocca, Elisabetta Merigo
One of the biggest challenges in endodontics is the complete disinfection of root canals. In addition to mechanical preparation, the technique traditionally also involves channel disinfection with other agents such as sodium hypochlorite, hydrogen peroxide, chlorhexidine, or a combination of these. Some bacterial species are particularly resistant to eradication. Using Enterococcus faecalis in this preliminary study, we tested the bactericidal effectiveness of the Fenton reaction and the photo-Fenton reaction using an LED light with a 400-nm wavelength...
June 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28212822/cryptosporidium-contaminated-water-disinfection-by-a-novel-fenton-process
#20
Sina Matavos-Aramyan, Mohsen Moussavi, Hedieh Matavos-Aramyan, Sara Roozkhosh
Three novel modified advanced oxidation process systems including ascorbic acid-, pro-oxidants- and ascorbic acid-pro-oxidants-modified Fenton system were utilized to study the disinfection efficiency on Cryptosporidium-contaminated drinking water samples. Different concentrations of divalent and trivalent iron ions, hydrogen peroxide, ascorbic acid and pro-oxidants at different exposure times were investigated. These novel systems were also compared to the classic Fenton system and to the control system which comprised of only hydrogen peroxide...
February 16, 2017: Free Radical Biology & Medicine
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