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hydrogen peroxide decontamination

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https://www.readbyqxmd.com/read/28893449/successful-control-of-2-simultaneous-outbreaks-of-oxa-48-carbapenemase-producing-enterobacteriaceae-and-multidrug-resistant-acinetobacter-baumannii-in-an-intensive-care-unit
#1
A Robustillo-Rodela, V Pérez-Blanco, M A Espinel Ruiz, G Ruiz Carrascoso, J C Figueira Iglesias, D Abad Martín
BACKGROUND: This report describes a double outbreak of OXA-48-producing Enterobacteriaceae (OXA-48-PE) and multidrug-resistant Acinetobacter baumannii (MRAB) in an intensive care unit (ICU) and the effectiveness of measures implemented, including decontamination with vaporized hydrogen peroxide (VHP). METHODS: Affected patients were isolated in a confined area and cared for by dedicated personnel. Four percent chlorhexidine soap was used for patient daily hygiene...
September 8, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28872735/in-vitro-efficacy-of-disinfectants-utilised-for-skin-decolonization-and-environmental-decontamination-during-a-hospital-outbreak-with-candida-auris
#2
A Abdolrasouli, D Armstrong-James, L Ryan, S Schelenz
Candida auris has caused nosocomial infections and transmissions within hospital settings. As little is known about the efficacy of skin and environmental decontamination products to kill C. auris this study investigated the in vitro activity of chlorine, chlorhexidine, iodine povidone and vaporized hydrogen peroxide products against C. auris. H2 O2 vapour showed 96.6-100% effective killing of C. auris. All isolates were inhibited by chlorhexidine gluconate concentrations at 0.125 to 1.5% and for iodinated povidone at 0...
September 5, 2017: Mycoses
https://www.readbyqxmd.com/read/28754034/effect-of-cultivation-ph-on-the-surface-hydrophobicity-of-bacillus-subtilis-spores
#3
Elisabeth Eschlbeck, Simon A W Bauer, Ulrich Kulozik
Bacillus subtilis spores are often used as biological indicators (BI) to monitor decontamination processes with gaseous hydrogen peroxide. Results in practical inactivation validation tests, however, vary considerably with no available explanation so far. This study reports on the effect of cultivation pH on spore surface hydrophobicity. Surface hydrophobicity is suspected to have an impact on the decontamination of technical surfaces such as packaging material when gaseous, condensing hydrogen peroxide is applied...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28736948/evaluating-the-efficacy-of-hydrogen-peroxide-vapour-against-foot-and-mouth-disease-virus-within-a-bsl4-biosafety-facility
#4
B M Petit, F C Almeida, T R Uchiyama, F O C Lopes, K H Tino, J Chewins
An evaluation was made of the efficacy of 35% hydrogen peroxide vapour (HPV) against foot-and-mouth disease virus (FMDV) in a biosafety facility. Biological indicators (BIs) were produced using three serotypes of FMDV, all with a titre of ≥10(6) TCID50 per ml. Fifteen BIs of each serotype were distributed across five locations, throughout a 30-m(3) airlock chamber, producing a total of 45 BIs. Thirty-five percent HPV was generated and applied using a Bioquell vaporization module located in the centre of the chamber...
October 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28672227/pyrimethanil-degradation-by-photo-fenton-process-influence-of-iron-and-irradiance-level-on-treatment-cost
#5
A Cabrera Reina, S Miralles-Cuevas, J L Casas López, J A Sánchez Pérez
This study evaluates the combined effect of photo-catalyst concentration and irradiance level on photo-Fenton efficiency when this treatment is applied to industrial wastewater decontamination. Three levels of irradiance (18, 32 and 46W/m(2)) and three iron concentrations (8, 20 and 32mg/L) were selected and their influence over the process studied using a raceway pond reactor placed inside a solar box. For 8mg/L, it was found that there was a lack of catalyst to make use of all the available photons. For 20mg/L, the treatment always improved with irradiance indicating that the process was photo-limited...
December 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28651076/application-of-water-assisted-ultraviolet-light-in-combination-of-chlorine-and-hydrogen-peroxide-to-inactivate-salmonella-on-fresh-produce
#6
Shuanghuan Guo, Runze Huang, Haiqiang Chen
With the demand for fresh produce increases in recent decades, concerns for microbiological safety of fresh produce are also raised. To identify effective ultraviolet (UV) light treatment for fresh produce decontamination, we first determined the effect of three forms of UV treatment, dry UV (samples were treated by UV directly), wet UV (samples were dipped in water briefly and then exposed to UV), and water-assisted UV (samples were treated by UV while being immersed in agitated water) on inactivation of Salmonella inoculated on tomatoes and fresh-cut lettuce...
June 19, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28642746/virucidal-activity-of-fogged-chlorine-dioxide-and-hydrogen-peroxide-based-disinfectants-against-human-norovirus-and-its-surrogate-feline-calicivirus-on-hard-to-reach-surfaces
#7
Naim Montazeri, Clyde Manuel, Eric Moorman, Janak R Khatiwada, Leonard L Williams, Lee-Ann Jaykus
Human norovirus (NoV) is the leading cause of foodborne illnesses in the United States. Norovirus is shed in high numbers in the feces and vomitous of infected individuals. Contact surfaces contaminated with bodily fluids harboring infectious virus particles serve as vehicles for pathogen transmission. Environmental stability of NoV and its resistance to many conventional disinfectants necessitate effective inactivation strategies to control the spread of virus. We investigated the efficacy of two commercial disinfectants, hydrogen peroxide (7...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28610932/automatic-environmental-disinfection-with-hydrogen-peroxide-and-silver-ions-versus-manual-environmental-disinfection-with-sodium-hypochlorite-a-multicentre-randomized-before-and-after-trial
#8
D Mosci, G W Marmo, L Sciolino, C Zaccaro, R Antonellini, L Accogli, T Lazzarotto, M Mongardi, M P Landini
BACKGROUND: New technologies for automated disinfection have been developed, including the use of hydrogen peroxide atomized by specific equipment, with associated silver compounds. AIMS: To compare the effectiveness of an automated disinfection system with hydrogen peroxide <8% and silver ion versus a manual method with 0.5% sodium hypochlorite solution when evaluating the reduction of microbial mesophilic contamination and Clostridium difficile presence; and to evaluate the time required for both of these processes...
June 10, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28524724/antibacterial-effect-of-hydrogen-peroxide-titanium-dioxide-suspensions-in-the-decontamination-of-rough-titanium-surfaces
#9
David Wiedmer, Fernanda Cristina Petersen, Jessica Lönn-Stensrud, Hanna Tiainen
The chemical decontamination of infected dental implants is essential for the successful treatment of peri-implantitis. The aim of this study was to assess the antibacterial effect of a hydrogen peroxide-titanium dioxide (H2O2-TiO2) suspension against Staphylococcus epidermidis biofilms. Titanium (Ti) coins were inoculated with a bioluminescent S. epidermidis strain for 8 h and subsequently exposed to H2O2 with and without TiO2 nanoparticles or chlorhexidine (CHX). Bacterial regrowth, bacterial load and viability after decontamination were analyzed by continuous luminescence monitoring, live/dead staining and scanning electron microscopy...
May 19, 2017: Biofouling
https://www.readbyqxmd.com/read/28512177/evaluation-of-novel-process-indicators-for-rapid-monitoring-of-hydrogen-peroxide-decontamination-processes
#10
Neil P McLeod, Melanie Clifford, J Mark Sutton
Geobacillus stearothermophilus spores on stainless steel discs are routinely used as Biological Indicators (BIs) for the validation of hydrogen peroxide bio-decontamination processes. Given ongoing concerns about the reliability and response time of BIs, we explored the potential for an enzyme-based approach decontamination process evaluation. Thermostable adenylate kinase (tAK) enzyme was coated onto a solid support and exposed to hydrogen peroxide vapour, in parallel with standard commercial 6-log BIs, during a series of vapour-phase hydrogen peroxide (VPHP) cycles in a flexible film isolator...
May 15, 2017: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/28500989/pharmaceuticals-benzene-toluene-and-chlorobenzene-removal-from-contaminated-groundwater-by-combined-uv-h2o2-photo-oxidation-and-aeration
#11
Ondřej Lhotský, Eva Krákorová, Pavel Mašín, Radim Žebrák, Lucie Linhartová, Zdena Křesinová, Josef Kašlík, Jana Steinová, Torgeir Rødsand, Alena Filipová, Klára Petrů, Kristýna Kroupová, Tomáš Cajthaml
This study was performed to test the feasibility of several decontamination methods for remediating heavily contaminated groundwater in a real contaminated locality in the Czech Republic, where a pharmaceuticals plant has been in operation for more than 80 years. The site is polluted mainly by recalcitrant psychopharmaceuticals and monoaromatic hydrocarbons, such as benzene, toluene and chlorobenzene. For this purpose, an advanced oxidation technique employing UV radiation with hydrogen peroxide dosing was employed, in combination with simple aeration pretreatment...
April 30, 2017: Water Research
https://www.readbyqxmd.com/read/28482224/use-of-photo-fenton-s-reaction-by-400-nm-led-light-for-endodontic-disinfection-a-preliminary-in-vitro-study-on-enterococcus-faecalis
#12
Giuseppe Lagori, Carlo Fornaini, Jean-Paul Rocca, Elisabetta Merigo
One of the biggest challenges in endodontics is the complete disinfection of root canals. In addition to mechanical preparation, the technique traditionally also involves channel disinfection with other agents such as sodium hypochlorite, hydrogen peroxide, chlorhexidine, or a combination of these. Some bacterial species are particularly resistant to eradication. Using Enterococcus faecalis in this preliminary study, we tested the bactericidal effectiveness of the Fenton reaction and the photo-Fenton reaction using an LED light with a 400-nm wavelength...
June 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28212822/cryptosporidium-contaminated-water-disinfection-by-a-novel-fenton-process
#13
Sina Matavos-Aramyan, Mohsen Moussavi, Hedieh Matavos-Aramyan, Sara Roozkhosh
Three novel modified advanced oxidation process systems including ascorbic acid-, pro-oxidants- and ascorbic acid-pro-oxidants-modified Fenton system were utilized to study the disinfection efficiency on Cryptosporidium-contaminated drinking water samples. Different concentrations of divalent and trivalent iron ions, hydrogen peroxide, ascorbic acid and pro-oxidants at different exposure times were investigated. These novel systems were also compared to the classic Fenton system and to the control system which comprised of only hydrogen peroxide...
February 16, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28196152/human-histologic-evidence-of-reosseointegration-around-an-implant-affected-with-peri-implantitis-following-decontamination-with-sterile-saline-and-antiseptics-a-case-history-report
#14
Paul Fletcher, Daniel Deluiz, Eduardo Mb Tinoco, John L Ricci, Dennis P Tarnow, Justine Monnerat Tinoco
The treatment of peri-implant disease is one of the most controversial topics in implant dentistry. The multifactorial etiology and the myriad proposed techniques for managing the problem make successful decontamination of an implant surface affected by peri-implantitis one of the more unpredictable challenges dental practitioners have to face. This article presents the first known published case report demonstrating human histologic evidence of reosseointegration using a plastic curette for mechanical debridement and dilute sodium hypochlorite, hydrogen peroxide, and sterile saline for chemical detoxification...
February 14, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28155914/evolutionary-clade-affects-resistance-of-clostridium-difficile-spores-to-cold-atmospheric-plasma
#15
Mairéad Connor, Padrig B Flynn, Derek J Fairley, Nikki Marks, Panagiotis Manesiotis, William G Graham, Brendan F Gilmore, John W McGrath
Clostridium difficile is a spore forming bacterium and the leading cause of colitis and antibiotic associated diarrhoea in the developed world. Spores produced by C. difficile are robust and can remain viable for months, leading to prolonged healthcare-associated outbreaks with high mortality. Exposure of C. difficile spores to a novel, non-thermal atmospheric pressure gas plasma was assessed. Factors affecting sporicidal efficacy, including percentage of oxygen in the helium carrier gas admixture, and the effect on spores from different strains representing the five evolutionary C...
February 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/27934804/use-of-hydrogen-peroxide-vapour-plasma-irradiation-in-combination-for-quick-decontamination-of-closed-chambers
#16
Devendra T Mourya, Hamish C Shahani, Pragya D Yadav, Pradip V Barde
BACKGROUND & OBJECTIVES: Various conventional methods such as gaseous, vapour and misting systems, fogging, manual spray and wipe techniques employing a number of chemical agents are used for decontamination of enclosed spaces. Among all these methods, use of aerosolized formaldehyde is the most preferred method due to cost-effectiveness and practical aspects. However, being extremely corrosive in nature generating very irritating fumes and difficulty in maintaining a high level of gas concentration, many laboratories prefer the vaporization of hydrogen peroxide (H 2 O 2 ) as an alternative...
August 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27866755/evaluation-of-an-automated-room-decontamination-device-using-aerosolized-peracetic-acid
#17
Thriveen S C Mana, Brett Sitzlar, Jennifer L Cadnum, Annette L Jencson, Sreelatha Koganti, Curtis J Donskey
Because manual cleaning is often suboptimal, there is increasing interest in use of automated devices for room decontamination. We demonstrated that an ultrasonic room fogging system that generates submicron droplets of peracetic acid and hydrogen peroxide eliminated Clostridium difficile spores and vegetative pathogens from exposed carriers in hospital rooms and adjacent bathrooms.
November 18, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27833595/chemical-and-stress-resistances-of-clostridium-difficile-spores-and-vegetative-cells
#18
Adrianne N Edwards, Samiha T Karim, Ricardo A Pascual, Lina M Jowhar, Sarah E Anderson, Shonna M McBride
Clostridium difficile is a Gram-positive, sporogenic and anaerobic bacterium that causes a potentially fatal colitis. C. difficile enters the body as dormant spores that germinate in the colon to form vegetative cells that secrete toxins and cause the symptoms of infection. During transit through the intestine, some vegetative cells transform into spores, which are more resistant to killing by environmental insults than the vegetative cells. Understanding the inherent resistance properties of the vegetative and spore forms of C...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27777756/first-hospital-outbreak-of-the-globally-emerging-candida-auris-in-a-european-hospital
#19
Silke Schelenz, Ferry Hagen, Johanna L Rhodes, Alireza Abdolrasouli, Anuradha Chowdhary, Anne Hall, Lisa Ryan, Joanne Shackleton, Richard Trimlett, Jacques F Meis, Darius Armstrong-James, Matthew C Fisher
BACKGROUND: Candida auris is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of C. auris in a London cardio-thoracic center between April 2015 and July 2016. This is the first report of C. auris in Europe and the largest outbreak so far. We describe the identification, investigation and implementation of control measures. METHODS: Data on C. auris case demographics, environmental screening, implementation of infection prevention/control measures, and antifungal susceptibility of patient isolates were prospectively recorded then analysed retrospectively...
2016: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/27746394/counting-the-cost-of-an-outbreak-of-carbapenemase-producing-enterobacteriaceae-an-economic-evaluation-from-a-hospital-perspective
#20
J A Otter, P Burgess, F Davies, S Mookerjee, J Singleton, M Gilchrist, D Parsons, E T Brannigan, J Robotham, A H Holmes
OBJECTIVE: To perform an economic evaluation on the cost associated with an outbreak of carbapenemase-producing Enterobacteriaceae (CPE). METHODS: We performed an observational economic evaluation of an outbreak of CPE (NDM-producing Klebsiella pneumoniae) affecting 40 patients in a group of five hospitals across three sites in West London. Costs were split into actual expenditure (including anti-infective costs, enhanced CPE screening, contact precautions, temporary ward-based monitors of hand and environmental practice, and environmental decontamination), and 'opportunity cost' (staff time, bed closures and elective surgical missed revenue)...
March 2017: Clinical Microbiology and Infection
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