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Jun Lv

Weirui Zhao, Huanru Ding, Sheng Hu, Jun Huang, Changjiang Lv, Jiaqi Mei, Zhihua Jin, Shanjing Yao, Lehe Mei
In the original publication of the article, the affiliations of authors Jun Huang, Changjiang Lv and Jiaqi Mei were misplaced. The correct information for author affiliations is provided in this correction.
June 21, 2018: Biotechnology Letters
Yonghuai Wang, Guangyuan Li, Chunyan Ma, Zhengyu Guan, Xuanyi Jin, Yang Li, Shuang Liu, Jun Yang
BACKGROUND: Septal leftward motion followed by a counter motion during early systole is known as septal flash (SF) in patients with isolated complete left bundle-branch block (cLBBB). This study aimed to determine the predictive value of SF for reduction of left ventricular (LV) global systolic function using 2D speckle-tracking echocardiography (2D STE) in cLBBB patients.Methods and Results:The study group of 41 patients with isolated cLBBB and preserved LV ejection fraction and 41 age- and sex-matched control subjects were studied...
June 21, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Jiahui Si, Canqing Yu, Yu Guo, Zheng Bian, Chenxi Qin, Ling Yang, Yiping Chen, Li Yin, Hui Li, Jian Lan, Junshi Chen, Zhengming Chen, Jun Lv, Liming Li
BACKGROUND: Existing evidence remains inconclusive as to the association between chronic hepatitis B virus (HBV) infection and the risk of chronic kidney disease (CKD). We prospectively examined the association between chronic HBV infection and CKD risk, and the joint associations of HBV infection with established risk factors of several lifestyle factors and prevalent diseases on CKD risk. METHODS: Participants from the China Kadoorie Biobank were enrolled during 2004-2008 and followed up until 31 December 2015...
June 18, 2018: BMC Medicine
Zhi-Ming Dai, Jian-Rui Lv, Kang Liu, Xiao-Ming Lei, Wei Li, Gang Wu, Xing-Han Liu, Yu-Xiao Zhu, Qian Hao, Zhi-Jun Dai
The role of rs4919510 polymorphism in microRNA-608 (miR-608) and cancer susceptibility and prognosis remain controversial and debatable. We conducted a meta-analysis of twenty-four eligible publications on the association of rs4919510 polymorphism with cancer risk and/or prognosis. Odds ratios, hazard ratios, and 95% confidence interval were used to investigate the association between this polymorphism and susceptibility, overall survival, and recurrence-free survival of cancer. Overall, eighteen case-control studies and nine cohort studies evaluated the susceptibility and prognostic value of rs4919510 polymorphism in cancer, respectively...
June 16, 2018: Aging
Xingyue Song, Jing Wu, Canqing Yu, Wenhong Dong, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Zhengming Chen, An Pan, Liming Li
BACKGROUND: Understanding the correlates of self-rated health (SRH) can help public health professionals prioritize health-promotion and disease-prevention interventions. This study aimed to investigate the association between multiple comorbidities and global SRH and age-comparative SRH. METHODS: A total of 512,891 participants aged 30-79 years old were recruited into the China Kadoorie Biobank study from ten regions between 2004 and 2008. Multivariate logistic regression models were used to estimate the odds ratios (ORs) for the associations between comorbidities (including diabetes, hypertension, coronary heart disease, rheumatic heart disease, stroke, tuberculosis, emphysema/bronchitis, asthma, cirrhosis/chronic hepatitis, peptic ulcer, gallbladder disease, kidney disease, fracture, rheumatic arthritis, psychiatric disorders, depressive symptoms, neurasthenia, head injury and cancer) and SRH...
June 15, 2018: BMC Public Health
Kejun Cheng, Xi Liu, Lu Chen, Jian-Min Lv, Fa-Jun Qu, Xiu-Wu Pan, Lin Li, Xin-Gang Cui, Yi Gao, Dan-Feng Xu
Prostate cancer (PCa) is one of the most commonly diagnosed urological malignancies. However, there are limited therapies for PCa patients who develop biochemical recurrence after androgen deprivation therapy (ADT). In the present study, we investigated the therapeutic efficacy and mechanism of α-Viniferin (KCV), an oligostilbene of trimeric resveratrol, against human PCa cells and found that it markedly inhibited the proliferation of LNCaP, DU145, and PC-3 cancer cells in a time- and dose-dependent manner, and had a strong cytotoxicity in non-androgen-dependent PCa cells...
June 15, 2018: Medical Oncology
Jun Zhang, Jing Lv, Shuang Pang, Xiaohong Bai, Fang Yuan, Yubin Wu, Hong Jiang, Guanqi Yang, Shaoqing Zhang
INTRODUCTION: Henoch-Schönlein purpura nephritis (HSPN) involves the renal impairment of Henoch-Schönlein purpura and can easily relapse into life-threatening late nephropathy in severe cases. Although there is a lack of validated evidence for its effectiveness, Chinese herbal medicine (CHM) is one of the most commonly used methods in China to treat HSPN. It is thus need to report the protocol of a prospective cohort trial using CHM to investigate the effectiveness, safety and advantages for children with HSPN...
June 2018: Medicine (Baltimore)
Juke Ma, Zhenghua Lv, Xiuxiu Liu, Xianfang Liu, Wei Xu
Multidrug resistance (MDR) is a major impediment to cancer therapy. MG‑132 has been identified to be effective against MDR in several types of cancer. However, the mechanism of MG‑132 in head and neck squamous cell carcinomas remains unknown. Based on our previous study, the present detected P‑gp and P‑gp expression in hypopharyngeal carcinoma FaDu cells, revealing that their expression was lower than that observed in the MDR cell line FaDu/T. To reverse the MDR of FaDu/T cells, the present study introduced MG‑132 and demonstrated that the high expression of P‑gp/P‑gp in FaDu/T cells was attenuated in a time‑dependent manner...
June 6, 2018: Molecular Medicine Reports
Le Gui, Xin Guo, Zhe Zhang, Hui Xu, Ya-Wei Ji, Ren-Jun Wang, Jiang-Hua Zhu, Qing-Hui Chen
Activation of the Ca2+ /calmodulin-dependent protein kinase II isoform δA (CaMKIIδA) disturbs intracellular Ca2+ homeostasis in cardiomyocytes during chronic heart failure (CHF). We hypothesized that upregulation of CaMKIIδA in cardiomyocytes might enhance Ca2+ leak from the sarcoplasmic reticulum (SR) via activation of phosphorylated ryanodine receptor type 2 (P-RyR2) and decrease Ca2+ uptake by inhibition of SR calcium ATPase 2a (SERCA2a). In this study, CHF was induced in rats by ligation of the left anterior descending coronary artery...
June 14, 2018: Acta Pharmacologica Sinica
Shengfeng Liu, Haiying Wang, Ming Song, Luxian Lv, Yue Cui, Yong Liu, Lingzhong Fan, Nianming Zuo, Kaibin Xu, Yuhui Du, Qingbao Yu, Na Luo, Shile Qi, Jian Yang, Sangma Xie, Jian Li, Jun Chen, Yunchun Chen, Huaning Wang, Hua Guo, Ping Wan, Yongfeng Yang, Peng Li, Lin Lu, Hao Yan, Jun Yan, Huiling Wang, Hongxing Zhang, Dai Zhang, Vince D Calhoun, Tianzi Jiang, Jing Sui
Multimodal fusion has been regarded as a promising tool to discover covarying patterns of multiple imaging types impaired in brain diseases, such as schizophrenia (SZ). In this article, we aim to investigate the covarying abnormalities underlying SZ in a large Chinese Han population (307 SZs, 298 healthy controls [HCs]). Four types of magnetic resonance imaging (MRI) features, including regional homogeneity (ReHo) from resting-state functional MRI, gray matter volume (GM) from structural MRI, fractional anisotropy (FA) from diffusion MRI, and functional network connectivity (FNC) resulted from group independent component analysis, were jointly analyzed by a data-driven multivariate fusion method...
April 20, 2018: Schizophrenia Bulletin
Xiong-Bai Zhu, Wen-Jun Lin, Chen Lv, Lu Wang, Zheng-Xiang Huang, Sheng-Wu Yang, Xin Chen
This study aims to explore the effects of miR-539 on osteoblast proliferation and differentiation and osteoclast apoptosis in a rat model of osteoporosis, and its mechanism involving the regulation of the AXIN1-mediated wingless-Int (Wnt) signaling pathway. A rat model of osteoporosis was successfully established by ovariectomy. With osteoblasts and osteoclasts of rats not receiving ovariectomy in the sham group as control, those of osteoporotic rats were treated with miR-539 inhibitor, miR-539 mimic, and AXIN1 shRNA...
June 12, 2018: Journal of Cellular Biochemistry
Xinyu Zheng, Shen Chen, Meiqin Zheng, Jun Peng, Xiaosan He, Yongming Han, Jingjing Zhu, Qingtie Xiao, Rixin Lv, Ruiyu Lin
A rapid, accurate and simple method was developed for the simultaneous determination of glutathione (GSH) and phytochelatins (PCs) by high-performance liquid chromatography (HPLC) with an evaporative light-scattering detector. GSH, phytochelatin 2 (PC2 ), PC3 , PC4 , PC5 and PC6 can be separated with baseline separation within 9 min using a Venusil AA column (250 mm × 4.6 mm i.d., 5 µm particle sizes). Acetonitrile and water containing 0.1% trifluoroacetic acid (0.1%) were employed as the mobile phase for the gradient elution...
May 2018: Royal Society Open Science
Ming-Rui Huo, Ya-Jing Xu, Shu-Zhen Zhai, Meng Lv, Yu Wang, Le-Qing Cao, Lan-Ping Xu, Xiao-Hui Zhang, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Wei Han, Yu-Qian Sun, Chen-Hua Yan, Fei-Fei Tang, Xiao-Dong Mo, Ming-Feng Zhao, Kai-Yan Liu, Xiao-Jun Huang, Ying-Jun Chang
We investigated the prevalence of and risk factors for antibodies to HLA in 1,663 haploidentical transplant candidates. Among these cases, 349 (21.0%) showed positive panel-reactive antibody (PRA) either for class I or class II HLA. Multivariate analysis showed the following: i) risk factors associated with the prevalence of PRA either for class I or class II HLA were female gender (P=0.018), prior transfusions (P<0.001) or pregnancy (P<0.001), and cases with MDS (P=0.018); compared to other patients, subjects with ALL had a lower prevalence of class I antibodies (P=0...
June 8, 2018: Human Immunology
Wenhong Dong, Xiong-Fei Pan, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Tangchun Wu, Zhengming Chen, An Pan, Liming Li
BACKGROUND AND PURPOSE: Self-rated health (SRH) is a consistent and strong predictor of all-cause and cardiovascular mortality in various populations. However, the associations between SRH measures and risk of first-ever or recurrent stroke were rarely explored. We thus aim to prospectively investigate the associations between SRH measures and risk of total and subtypes of stroke in Chinese population. METHODS: A total of 494,113 participants from the China Kadoorie Biobank without prior heart diseases or cancer (486,541 without stroke and 7,572 with stroke) were followed from baseline (2004 to 2008) until December 31, 2013...
May 2018: Journal of Stroke
Guo-Hao Huang, Lei Du, Ningning Li, Ying Zhang, Yan Xiang, Jun-Hai Tang, Shuli Xia, Eric Erquan Zhang, Sheng-Qing Lv
Gliomas with isocitrate dehydrogenases genes mutation (IDHMT ) were found to be less aggressive than their wildtype (IDHWT ) counterparts. However, the mechanism remains unclear. The current study aims to investigate the role of silenced oncogenic microRNAs in IDHMT gliomas, which were largely ignored and may contribute to the less aggressive behavior of IDHMT gliomas. Microarrays, bioinformatics analysis of the data from TCGA and qPCR analysis of samples from our experimental cohort (LGG: IDHWT =10, IDHMT =31; GBM: IDHWT =34, IDHMT =9) were performed...
June 6, 2018: Cancer Letters
Sheng-Li Shi, Jun-Ping Lv, Qi Liu, Fang-Ru Nan, Xiao-Yan Jiao, Jia Feng, Shu-Lian Xie
The ability of the agricultural residue of Phragmites australis to serve as an absorbent material used to remove phenol from aqueous solutions in batch and continuous fixed-bed columns was investigated. Prepared adsorbents were characterized by SEM, FTIR, and pHpzc methods. The equilibrium adsorption (qe) of phenol was increased from 9.61 to 29.40 mg/g when the initial phenol concentrations increased from 50 to 150 mg/L. The max adsorption capacity of Phragmites australis was found to be 29.60 mg/g at 30 °C...
June 7, 2018: Environmental Science and Pollution Research International
Hyun Oh Park, Joung Hun Byun, Seong Ho Moon, Jong Woo Kim, Sung Hwan Kim, Ki Nyun Kim, Jae Jun Jung, Dong Hoon Kang, Jun Young Choi, Jun Ho Yang, In Seok Jang, Chung Eun Lee
BACKGROUND: The pseudoaneurysms of sinus of Valsalva is an uncommon and serious complication of an infection, trauma, or after cardiac surgery or procedure. Pseudoaneurysms of sinus of Valsalva from left is rare. We describe a case of pseudoaneurysm of the left coronary sinus of Valsalva invaded into the left ventricle (LV) diagnosed by transthoracic echocardiography (TTE), transesophageal ecoccardiography (TEE), and multiple detector computed tomography (MDCT). CASE PRESENTATION: A 44-year-old male patient had New York Heart Association (NYHA) class II / III dyspnea during 4 months...
June 7, 2018: Journal of Cardiothoracic Surgery
Yanfei Zhu, Hui Wang, Kaiwei Wan, Jun Guo, Chunting He, Yue Yu, Luyang Zhao, Yin Zhang, Jiawei Lv, Lin Shi, Renxi Jin, Xinxiang Zhang, Xinhua Shi, Zhiyong Tang
Au20(PP3)4Cl4 (PP3 = tris(2-(diphenylphosphino)ethyl) phosphine), abbreviated as Au20, is the only Au nanocluster of intrinsic core chirality without chiral environment (chiral ligands or Au-thiolate staples) by far, making it a unique object to understand chiral evolution and develop innovative application. Unfortunately, the synthesized Au20 is racemic, and its enantiomer remains not isolated yet. Here, we report a supramolecular assembly strategy with α-cyclodextrin (α-CD) to afford enantiopure Au20 in massive production, and the enantiomer excess (ee) value of as-separated Au20 reaches 97%...
June 6, 2018: Angewandte Chemie
Zhi Jiang, Huan Zhang, Chunliang Liu, Jun Yin, Shan Tong, Junxing Lv, Shaohua Wei, Shiliang Wu
β1,3-N-acetylglucosaminyltransferase (β3GnT8) and β3GnT2 are key enzymes that catalyzes the formation of polylactosamine glycan structures by transferring GlcNAc to tetra-antennary β1-6-branched N -glycan and it also has an important effect on the progression of various types of human cancer. They have been reported to participate in tumor invasion and metastasis by regulating the expression of matrix metalloproteinases (MMPs), CD147, and polylactosamine. However, whether β3GnT8 and β3GnT2 play a role in colorectal cancer and, if so, the underlying mechanisms remain unclear...
2018: Frontiers in Physiology
Ya-Ying Wang, Yu-Qiu Li, Hong-Yan Wu, Bo Hu, Jia-Jia Zheng, Hong Zhai, Shi-Xiang Lv, Xin-Lei Liu, Xin Chen, Hong-Mei Qiu, Jiayin Yang, Chun-Mei Zong, De-Zhi Han, Zi-Xiang Wen, De-Chun Wang, Zheng-Jun Xia
Soybean was domesticated about 5,000 to 6,000 years ago in China. Although genotyping technologies such as genotyping by sequencing (GBS) and high-density array are available, it is convenient and economical to genotype cultivars or populations using medium-density SNP array in genetic study as well as in molecular breeding. In this study, 235 cultivars, collected from China, Japan, USA, Canada and some other countries, were genotyped using SoySNP8k iSelect BeadChip with 7,189 single nucleotide polymorphisms (SNPs)...
2018: Frontiers in Plant Science
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