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Jun Lv

Maryam Sardar, Chen Jun, Zaka Ullah, Aasma Tabassum, Mohsan Jelani, Ju Cheng, Yuxiang Sun, Xueming Lv, Lu Jian
We irradiate the single crystal boron-doped silicon (Si) at various laser fluences with 100 laser shots in ambient air at room temperature using an Nd:YAG laser and investigate its surface morphology and optical properties. The optical microscopy gives evidence of the formation of a crater and reveals that the heat-affected zone and melted area are increased with increase in laser fluence from 1.1 to 15.4  J/cm2 . The micrographs obtained by scanning electron microscopy (SEM) show that the micro- and nano-structures such as microcracks, bubbles, nucleation sites, clusters, redeposited layered material, nanoparticles, and alike water droplet structures are formed on a laser-exposed Si surface...
February 20, 2018: Applied Optics
Dang Hui, Jin Jia-Ning, Xu Jing, Li Shi-Zhu, Zhou Xiao-Nong, Sun Jun-Ling, Li Zhong-Jie, Lv Shan
OBJECTIVE: To analyze the investigation data of the national schistosomiasis surveillance sites in 2015, so as to provide scientific evidences for schistosomiasis control, elimination and surveillance. METHODS: According to National Schistosomiasis Surveillance Programme (version 2014), 457 surveillance sites were selected, and the investigation data in residents, floating population, domestic animals and Oncomelania hupensis snails were collected and analyzed from four types of endemic counties...
June 12, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
Hu Fei, Lv Shang-Biao, Li Yi-Feng, Li Zhao-Jun, Ge Jun, Yuan Min, Chen Zhe, Liu Yue-Ming, Lin Dan-Dan
OBJECTIVE: To grasp the distribution status of Oncomelania hupensis snails in Poyang Lake area, so as to provide the evidence for formulating and adjusting the schistosomiasis prevention and control strategy in lake areas. METHODS: The vector grid was created and sampled randomly by 200 m × 200 m in the spatial database of grassland, and the distribution of snails was investigated in the selected grid by using the method of mechanical sampling by 50 m × 50 m. At the same time, the elevation of investigation points was extracted based on the topographic map of Poyang Lake...
August 29, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
Cong Lu, Jingwei Lv, Liming Dong, Ning Jiang, Yan Wang, Qiong Wang, Yinghui Li, Shanguang Chen, Bei Fan, Fengzhong Wang, Xinmin Liu
20(S)-protopanaxatriol (PPT), one of the ginsenosides from Panax ginseng, has been reported to have neuroprotective effects and to improve memory. The present study was designed to investigate the protective effect of PPT on scopolamine-induced cognitive deficits in mice. Male Institute of Cancer Research mice were pretreated with 2 different doses of PPT (20 and 40 μmol/kg) for 27 days by intraperitoneal injection, and scopolamine (0.75 mg/kg) was injected intraperitoneally for 9 days to induce memory impairment...
February 22, 2018: Phytotherapy Research: PTR
Ye Tian, Haihua Feng, Lu Han, Lin Wu, Hongming Lv, Bingyu Shen, Zheng Li, Qiaoling Zhang, Guowen Liu
Magnolol (MG) is a kind of lignin isolated from Magnolia officinalis , which serves several different biological functions, such as antifungal, anticancer, antioxidant, and hepatoprotective functions. This study aimed to evaluate the protective effect of MG against oleic acid (OA)-induced hepatic steatosis and inflammatory damage in HepG2 cells and in a tyloxapol (Ty)-induced hyperlipidemia mouse model. Our findings indicated that MG can effectively inhibit OA-stimulated tumor necrosis factor α (TNF-α) secretion, reactive oxygen species generation, and triglyceride (TG) accumulation...
2018: Frontiers in Immunology
Fang Yuan, Fang Yang, Changhu Xue, Kangjun Wang, Qiuwu Liu, Jun Zhou, Feng Fu, Xiaocheng Wang, Wei Zhang, Yi Liu, Kang Huo, Hua Lv, Wen Jiang
BACKGROUND: No ideal blood pressure (BP) range has been scientifically determined for acute stroke, and no studies on BP management have been carried out for patients with severe stroke. This trial aims to investigate whether individualized lowering of elevated BP would improve the outcome in patients with severe stroke. METHODS/DESIGN: The CHASE trial is a multicenter, randomized, controlled study. A total of 500 adult patients with acute severe stroke will be enrolled in 18 study sites in China and randomized to individualized BP lowering (10-15% reduction from admission level) or guideline-recommended BP lowering...
February 21, 2018: Trials
Byung Joo Sun, Jae-Hyeong Park, Su-Jin Yoo, Yunseon Park, Yeon Ju Kim, In Suk Lee, Jinhyun Kim, In Seol Yoo, Seung Cheol Shim, Seong Wook Kang, Jun-Hyung Kim, Jae-Hwan Lee, Si Wan Choi, Jin-Ok Jeong, In-Whan Seong
PURPOSE: Although cardiac manifestation of Behçet disease (BD) has been described in sporadic reports, its timely diagnosis remains difficult. The objective of this study was to describe early cardiac manifestations of BD. We also performed a comprehensive classification of systemic BD activity and compared their cardiac manifestations. METHODS: A prospective screening using speckle tracking echocardiography was performed in 85 patients with BD who had no history of heart disease...
February 16, 2018: Echocardiography
Ruidong Zhu, Danhui Weng, Shichun Lu, Dongdong Lin, Menglong Wang, Dongdong Chen, Jun Lv, Hongjun Li, Fudong Lv, Ling Xi, Jianfeng Zhou, Ding Ma, Ning Li
The present clinical trial assessed the effect of double-dose administration of replication-deficient adenovirus-thymidine kinase and ganciclovir (ADV-TK/GCV) in patients with advanced hepatocellular carcinoma (HCC) who underwent liver transplantation (LT). Eighty-six patients with single tumor diameters >5 cm or multiple tumors with diameters >3 cm each, regardless of vascular invasion, were examined over a follow-up period of 61 months. All patients underwent orthotopic LT; 43 received LT only, and 43 received LT plus double-dose ADV-TK/GCV gene therapy (LT + ADV-TK/GCV)...
February 2018: Human Gene Therapy
Xiao-Yi Lv, Jun-Wei Hou, Zhi-Xian Gao, Hong-Fei Liu
CdS nanowires arrays were successfully synthesized by a simple solvothermal process using AAO as templates. The phase structures, morphologies, and optical properties of the products were investigated by X-ray diffraction, scanning electron microscopy, high-resolution transmission electron microscopy, Raman spectroscopy, and photoluminescence spectroscopy. It was found that the nanowires were composed of hexagonal structure CdS nanoparticles and the average diameters is about 60-70 nm. A strong green emission with a maximum around 505 nm was observed from the synthesized CdS nanowires at room temperature, which was attributed to near-band-edge emission...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Haowen Zhong, Ya Liu, Zhenjian Xu, Peifeng Liang, Hui Yang, Xiao Zhang, Jun Zhao, Junzhen Chen, Sha Fu, Ying Tang, Jun Lv, Julie Wang, Nancy Olsen, Anping Xu, Song Guo Zheng
Lupus nephritis is one of most severe complications of systemic erythematosus lupus and current approaches are not curative for lupus nephritis. Although CD4+Foxp3+regulatory T cells (Treg) are crucial for prevention of autoimmunity, the therapeutic effect of these cells on lupus nephritis is not satisfactory. We previously reported that CD8+CD103+Treg induced ex vivo with TGF-β1 and IL-2 (CD8+CD103+iTreg), regardless of Foxp3 expression, displayed potent immunosuppressive effect on Th cell response and had therapeutic effect on Th cell-mediated colitis...
2018: Frontiers in Immunology
Jun Hyung Kim, Ki-Woon Kang, Jung Yeon Chin, Tae-Seok Kim, Jae-Hyeong Park, Yu Jeong Choi
OBJECTIVES: The predictors of pacing-induced cardiomyopathy (PICM) for complete atrioventricular block (CAVB) have not yet been defined. The aim of this study was to investigate the major determinant of the occurrence of PICM. SETTING: This is a multicentre, retrospective analysis of CAVB from tertiary referral centres in Daejeon, South Korea. PARTICIPANTS: A cohort of 900 consecutive patients with an implanted pacemaker was collected from December 2001 to August 2015...
February 8, 2018: BMJ Open
Xiaolong Zhao, Jun Ma, Xiangheng Xiao, Qi Liu, Lin Shao, Di Chen, Sen Liu, Jiebin Niu, Xumeng Zhang, Yan Wang, Rongrong Cao, Wei Wang, Zengfeng Di, Hangbing Lv, Shibing Long, Ming Liu
Cation-based resistive switching (RS) devices, dominated by conductive filaments (CF) formation/dissolution, are widely considered for the ultrahigh density nonvolatile memory application. However, the current-retention dilemma that the CF stability deteriorates greatly with decreasing compliance current makes it hard to decrease operating current for memory application and increase driving current for selector application. By centralizing/decentralizing the CF distribution, this current-retention dilemma of cation-based RS devices is broken for the first time...
February 13, 2018: Advanced Materials
Yun-Dai Chen, Wei-Yi Fang, Ji-Yan Chen, Zhan-Ming Fan, Chuan-Yu Gao, Jun-Bo Ge, Zuo-Xiang He, Yong Huo, Lang Li, Si-Jin Li, Xi-Lie Lu, Bin Lv, Ju-Ying Qian, Ya-Jun Shi, Zhu-Jun Shen, Jing Wang, Yi-Ning Wang, Lei Xu, Li Yang, Bo Yu, Mei Zhang, Jun-Jie Yang, Shu-Yang Zhang, Xiao-Li Zhang, Shi-Hua Zhao, Yang Zheng, Yu-Chi Han, Guang Zhi
No abstract text is available yet for this article.
January 2018: Journal of Geriatric Cardiology: JGC
Yuying Liu, Jiadi Lv, Jinyan Liu, Xiaoyu Liang, Xun Jin, Jing Xie, Le Zhang, Degao Chen, Roland Fiskesund, Ke Tang, Jingwei Ma, Huafeng Zhang, Wenqian Dong, Siqi Mo, Tianzhen Zhang, Feiran Cheng, Yabo Zhou, Qingzhu Jia, Bo Zhu, Yan Kong, Jun Guo, Haizeng Zhang, Zhuo-Wei Hu, Xuetao Cao, F Xiao-Feng Qin, Bo Huang
Dynamic interaction with the immune system profoundly regulates tumor cell dormancy. However, it is unclear how immunological cues trigger cancer cell-intrinsic signaling pathways for entering into dormancy. Here, we show that IFN-β treatment induced tumor-repopulating cells (TRC) to enter dormancy through an indolamine 2,3-dioxygenase/kynurenine/aryl hydrocarbon receptor/p27-dependent (IDO/Kyn/AhR/p27-dependent) pathway. Strategies to block this metabolic circuitry did not relieve dormancy, but led to apoptosis of dormant TRCs in murine and human melanoma models...
February 12, 2018: Journal of Clinical Investigation
Lei Yao, Duanyang Xie, Li Geng, Dan Shi, Jian Huang, Yufei Wu, Fei Lv, Dandan Liang, Li Li, Yi Liu, Jun Li, Yi-Han Chen
BACKGROUND: Heart failure is a complex syndrome characterized by cardiac contractile impairment with high mortality. Defective intracellular Ca2+ homeostasis is the central cause under this scenario and tightly links to ultrastructural rearrangements of sarcolemmal transverse tubules and the sarcoplasmic reticulum (SR); however, the modulators of the SR architecture remain unknown. The SR has been thought to be a specialized endoplasmic reticulum membrane system. Receptor accessory proteins (REEPs)/DP1/Yop1p are responsible for shaping high-curvature endoplasmic reticulum tubules...
February 3, 2018: Journal of the American Heart Association
Xiaoguang Chen, Qiongxia Lv, Jun Ma, Yumei Liu
OBJECTIVES: The PLCG2 (PLCγ2) gene is a member of PLC gene family encoding transmembrane signalling enzymes involved in various biological processes including cell proliferation and apoptosis. Our earlier study indicated that PLCγ2 may be involved in the termination of regeneration of the liver which is mainly composed of hepatocytes, but its exact biological function and molecular mechanism in liver regeneration termination remains unclear. This study aims to examine the role of PLCγ2 in the growth of hepatocytes...
February 11, 2018: Cell Proliferation
Tsubasa Tomoto, Tomoko Imai, Shigehiko Ogoh, Seiji Maeda, Jun Sugawara
Aorta effectively buffers cardiac pulsatile fluctuation generated from the left ventricular (LV) which could be a mechanical force to high blood flow and low-resistance end-organs such as the brain. A dynamic orthostatic challenge may evoke substantial cardiac pulsatile fluctuation via the transient increases in venous return and stroke volume (SV). Particularly, this response may be greater in endurance-trained athletes (ET) who exhibit LV eccentric remodeling. The aim of this study was to determine the contribution of aortic compliance to the response of cerebral blood flow fluctuation to dynamic orthostatic challenge in ET and age-matched sedentary (SED) young healthy men...
2018: Frontiers in Physiology
Jing Lv, Jijun Liu, Lei Guo, Jun Zhang, Yan Cheng, Chu Chen, Heping Zhao, Jihan Wang
Barrett's esophagus (BE) is defined as a metaplasia condition in the distal esophagus, in which the native squamous epithelium lining is replaced by a columnar epithelium with or without intestinal metaplasia. It is commonly accepted that BE is a precancerous lesion for esophageal adenocarcinoma. The aim of this study was to investigate the aberrant microRNAs (miRNAs) and differentially expressed genes (DEGs) associated with BE based on online microarray datasets. One miRNA and five gene expression profiling datasets were retrieved from the Gene Expression Omnibus Database...
February 8, 2018: Cell Cycle
Xiao-Ping Huang, Xiao Wang, Xiao-Lan Xie, Gao-Ping Zhang, Feng-Jiao Lv, Wen-Ting Weng, Fei Qiu, Zhao-Fa Li, Jun-Sheng Lin, Yong Diao
Kallistatin is a unique serine proteinase inhibitor and heparin-binding protein. A previous study conducted by our group indicated that kallistatin has antiangiogenic and antitumoral activities. In the present study, we report that kallistatin specifically binds to membrane surface-expressed nucleolin with high affinity. Antibody-mediated neutralization or siRNA-induced nucleolin knockdown results in loss of kallistatin suppression of endothelial cell proliferation and migration in vitro and tumor angiogenesis and growth in vivo...
January 5, 2018: Oncotarget
Xiao-Yan Zhu, Zhi-Suo Lv, Jiu-Ju Feng, Pei-Xin Yuan, Lu Zhang, Jian-Rong Chen, Ai-Jun Wang
To realize the efficient and complete removal of organic pollutants in waste water, it is highly urgent for scalable synthesis of either self-supported bimetallic nanocatalysts or anchored on carbon-based materials. In this study, a simple one-pot coreduction method was developed for preparing well-dispersed AgPd alloyed nanoclusters uniformly dispersed on reduced graphene oxide (AgPd NCs/rGO) at room temperature by utilizing 5-azacytosine as the capping agent. The nanocomposites were characterized by a set of physical characterizations...
January 16, 2018: Journal of Colloid and Interface Science
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