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Liming Li

Om P Kurmi, Kourtney J Davis, Kin Bong Hubert Lam, Yu Guo, Julien Vaucher, Derrick Bennett, Jenny Wang, Zheng Bian, Huaidong Du, Liming Li, Robert Clarke, Zhengming Chen
Introduction: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, with COPD deaths in China accounting for one-third of all such deaths. However, there is limited available evidence on the management of COPD in China. Methods: A random sample of 25 011 participants in the China Kadoorie Biobank, aged 38-87 years, from 10 regions in China was surveyed in 2013-2014. Data were collected using interviewer-administered questionnaires on the diagnosis ('doctor-diagnosed' or 'symptoms-based') and management of COPD (including use of medication and other healthcare resources), awareness of diagnosis and severity of symptoms in COPD cases...
2018: BMJ Open Respiratory Research
Yiping Chen, Christiana Kartsonaki, Robert Clarke, Yu Guo, Canqing Yu, Zheng Bian, Qilian Jiang, Shanpeng Li, Junshi Chen, Liming Li, Zhengming Chen
BACKGROUND: Inadequate sleep duration and insomnia can affect both physical and mental health. There is limited evidence, however, on characteristics and correlates of sleep patterns and insomnia in urban and rural China. METHODS: This cross-sectional study, involving 512,891 adults aged 30-79 years from ten (five urban and five rural) diverse areas in China, recorded detailed information, using interviewer-administered laptop-based questionnaires, on sleep patterns (duration, daytime napping and snoring) and insomnia symptoms...
April 2018: Sleep Medicine
Bing Li, Junsheng Zheng, Hongyou Zhang, Liming Jin, Daijun Yang, Hong Lv, Chao Shen, Annadanesh Shellikeri, Yiran Zheng, Ruiqi Gong, Jim P Zheng, Cunman Zhang
Among the various energy-storage systems, lithium-ion capacitors (LICs) are receiving intensive attention due to their high energy density, high power density, long lifetime, and good stability. As a hybrid of lithium-ion batteries and supercapacitors, LICs are composed of a battery-type electrode and a capacitor-type electrode and can potentially combine the advantages of the high energy density of batteries and the large power density of capacitors. Here, the working principle of LICs is discussed, and the recent advances in LIC electrode materials, particularly activated carbon and lithium titanate, as well as in electrolyte development are reviewed...
March 12, 2018: Advanced Materials
Pengcheng Sun, Heng Li, Zhuofan Lu, Xiaofan Su, Zengguang Ma, Jianpin Chen, Liming Li, Chuanqing Zhou, Yao Chen, Xinyu Chai
BACKGROUND: Electrical stimulation has been widely used in many ophthalmic diseases to modulate neuronal activities or restore partial visual function. Due to the different processing pathways and mechanisms, responses to visual and electrical stimulation in the primary visual cortex and higher visual areas might be different. This differences would shed some light on the properties of cortical responses evoked by electrical stimulation. OBJECTIVE: This study's goal was to directly compare the cortical responses evoked by visual and electrical stimulation and investigate the cortical processing of visual information and extrinsic electrical signal...
February 21, 2018: Brain Stimulation
Linghui Luo, Yong Gao, Cao Yang, Zengwu Shao, Xinghuo Wu, Shuai Li, Liming Xiong, Chao Chen
Most low back pain is caused by intervertebral discs (IVD) degeneration, a disease that prevalence is increasing with age. Halofuginone, an analog of ferbrifugine isolated from plant Dichroa febrifuga, has drawn much attention in recent years for the wide range of bioactivities in malaria, cancer, fibrotic and autoimmune diseases. In this study, we evaluated the benefit effects of halofuginone in IVD degeneration treatment in a validated rabbit puncture model. Halofuginone treatment could attenuate disc degeneration by suppressing the decrease of discs height and nucleus pulposus signal strength...
March 7, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Jianqin Tang, Huige Zhou, Xiaoyang Hou, Liming Wang, Yaxi Li, Yanyu Pang, Chunying Chen, Guan Jiang, Yanqun Liu
Chemotherapy is an important treatment for malignant tumors; however, its efficacy and clinical application are limited by its side effects and drug resistance properties. Chemotherapy and phototherapy exhibit synergistic anti-tumor effects. In the present study, a carboxylated poly(amido-amine) (PAMAM) with low cytotoxicity was synthesized as a delivery nanocarrier for loading chemotherapeutic drugs, temozolomide (TMZ), and fluorescent dye indocyanine green (ICG). Hyaluronic acid (HA), which targets the CD44-overexpressing cancer cells, was modified on the nanocarrier surface to enhance the selective killing of melanoma cells...
March 7, 2018: Cancer Letters
Ruiwei Meng, Na Liu, Canqing Yu, Xiongfei Pan, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Zhengming Chen, An Pan, Liming Li
OBJECTIVE: We aimed to prospectively evaluate the association between major depressive episode (MDE) and risk of type 2 diabetes in a Chinese population. METHODS: We used data from the China Kadoorie Biobank study, in which 461,213 participants free of diabetes, coronary heart disease, stroke, and cancer were followed from baseline (2004-2008) to December 31, 2013. A modified Chinese version of Composite International Diagnostic Interview Short-Form (CIDI-SF) was used to assess past year MDE...
February 17, 2018: Journal of Affective Disorders
Guangyuan Ren, Liangliang Gao, Chao Teng, Yunan Li, Hequn Yang, Jianglan Shui, Xianyong Lu, Ying Zhu, Liming Dai
The method of fabricating non-precious-metal electrocatalysts with high activity and durability through a facile and eco-friendly procedure is of great significance to the development of low cost fuel cells and metal-air batteries. Herein, we present that an ancient chemical reaction of "Pharaoh's snakes" can be a fast and convenient technique to prepare Fe/N-doped carbon nanosheets/nanotubes (Fe/N-C) electrocatalysts with sugar, soda, melamine and iron nitrate as precursors. The resultant Fe/N-C catalyst has a hierarchically porous structure, large surface area and uniformly distributed active sites...
March 9, 2018: ACS Applied Materials & Interfaces
Feijie Wang, Liang Sun, Qi Sun, Liming Liang, Xianfu Gao, Rongxia Li, An Pan, Huaixing Li, Yueyi Deng, Frank B Hu, Jiarui Wu, Rong Zeng, Xu Lin
BACKGROUND AND OBJECTIVES: Metabolomics is instrumental in identifying novel biomarkers of kidney function to aid in the prevention and management of CKD. However, data linking the metabolome to incident eGFR are sparse, particularly in Asian populations with different genetic backgrounds and environmental exposures. Therefore, we aimed to investigate the associations of amino acid and acylcarnitine profiles with change in eGFR in a Chinese cohort. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This study included 1765 community-living Chinese adults aged 50-70 years with baseline eGFR≥60 ml/min per 1...
March 8, 2018: Clinical Journal of the American Society of Nephrology: CJASN
Tingting Zhang, Wensong Wei, Bin Zhao, Ranran Wang, Mingliu Li, Liming Yang, Jianhua Wang, Qun Sun
This study investigated the possibility of using visible and near-infrared (VIS/NIR) hyperspectral imaging techniques to discriminate viable and non-viable wheat seeds. Both sides of individual seeds were subjected to hyperspectral imaging (400-1000 nm) to acquire reflectance spectral data. Four spectral datasets, including the ventral groove side, reverse side, mean (the mean of two sides' spectra of every seed), and mixture datasets (two sides' spectra of every seed), were used to construct the models. Classification models, partial least squares discriminant analysis (PLS-DA), and support vector machines (SVM), coupled with some pre-processing methods and successive projections algorithm (SPA), were built for the identification of viable and non-viable seeds...
March 8, 2018: Sensors
Liming Dong, Yanpei Li, Dongwei Xue, Yili Liu
The role of protein l-isoaspartate (d-aspartate) O-methyltransferase (PCMT1) in human cancer was generally cognized. The clinical significance and biological function of PCMT1 in bladder cancer is still unknown. PCMT1 mRNA and protein expression levels in bladder cancer tissues and cell lines were detected by qRT-PCR, immunohistochemistry, or western blot. The correlation between PCMT1 expression and clinicopathological factors was analyzed through immunohistochemistry in 108 bladder cancer patients. Loss-of-function and gain-of-function studies were conducted to explore the biological function of PCMT1 in bladder cancer cell lines in regulating cell proliferation, migration, and invasion...
March 8, 2018: IUBMB Life
Xilin Sun, Zunyu Xiao, Gongyan Chen, Zhaoguo Han, Yang Liu, Chongqing Zhang, Yingying Sun, Yan Song, Kai Wang, Fang Fang, Xiance Wang, Yanhong Lin, Lili Xu, Liming Shao, Jin Li, Zhen Cheng, Sanjiv Sam Gambhir, Baozhong Shen
Tumor heterogeneity and changes in epidermal growth factor receptor (EGFR) mutation status over time challenge the design of effective EGFR tyrosine kinase inhibitor (TKI) treatment strategies for non-small cell lung cancer (NSCLC). Therefore, there is an urgent need to develop techniques for comprehensive tumor EGFR profiling in real time, particularly in lung cancer precision medicine trials. We report a positron emission tomography (PET) tracer, N -(3-chloro-4-fluorophenyl)-7-(2-(2-(2-(2-18 F-fluoroethoxy) ethoxy) ethoxy) ethoxy)-6-methoxyquinazolin-4-amine (18 F-MPG), with high specificity to activating EGFR mutant kinase...
March 7, 2018: Science Translational Medicine
Bin Huang, Zhongwu Li, Dingqiang Li, Zaijian Yuan, Xiaodong Nie, Jinquan Huang, Yaoyu Zhou
Immobilization method using amendments is a very effective way of remediating heavy metal polluted soil. Passivator types and ambient conditions, such as moisture regimes, are the main factors affecting the immobilization efficiency. In this study, the immobilization of cadmium (Cd) was evaluated in red paddy soil amended with four different passivators (biochar, lime (CaO), calcium dihydrogen phosphate (Ca(H2 PO4 )2 ) and zeolite (modified with NaOH)) for three moisture regimes (70% water-holding capacity (WHC), continuous flooding (CF) and wetting-drying cycle (WDC))...
March 7, 2018: Environmental Technology
Yunpeng Zhao, Ying Feng, Jianqi Li, Yongzhao Guo, Liming Chen, Sitong Liu
Anammox aggregates have been extensively observed in high-efficiency nitrogen-removal reactors, yet the variation and inherent cause of its aggregation capacity related to reactor operation are still unknown. Here, we used microbial detection, metabolomics, extended DLVO theory and multivariate statistical analysis to address this issue. The aggregation capacity of anammox consortia varied periodically during reactor operation, which was determined by the hydrophobic force and the ratio of extracellular protein (PN) to extracellular polysaccharides (PS)...
March 5, 2018: Environmental Science & Technology
Xiaoxing Qi, Raymond Yu Wang, Jianchun Li, Tao Zhang, Liming Liu, Yanling He
Rapid population growth and environmental deterioration make ensuring food security with lower environmental costs fundamental to realizing sustainable development in China and other developing countries. The conceptual framework used in this paper integrates the major consequences of intensive agricultural land use and the diverse objectives of policymakers and farmers. It also offers an operational approach, based on farmers' diverse performance in grain production and farmland productivity, to assess food production and environmental impacts under foci-differentiated scenarios...
March 1, 2018: Journal of Environmental Management
Danli Sheng, Tianzhi Liu, Liming Deng, Liang Zhang, Xuelin Li, Jie Xu, Lan Hao, Pan Li, Haitao Ran, Hangrong Chen, Zhigang Wang
As a highly biocompatible NIR dye, indocyanine green (ICG) has been widely explored for cancer treatment due to its various energy level transition pathways upon NIR light excitation simultaneously, which leads to different theranostic effects (eg. Photoacoustic (PA) and fluorescence imaging (FL), photodynamic and photothermal therapy (PDT&PTT)). However, the theranostic efficiency of ICG is restricted intrinsically, owing to the competitive relationship of its co-existing imaging and therapeutic effect...
February 24, 2018: Biomaterials
Liming Miao, Yanxia Lv, Lijun Kong, Qizhen Chen, Chaoquan Chen, Jia Li, Fanhuan Zeng, Shenyun Wang, Jianbin Li, Li Huang, Jiashu Cao, Xiaolin Yu
BACKGROUND: Members of the MtN3/saliva/SWEET gene family are present in various organisms and are highly conserved. Their precise biochemical functions remain unclear, especially in Chinese cabbage. Based on the whole genome sequence, this study aims to identify the MtN3/saliva/SWEETs family members in Chinese cabbage and to analyze their classification, gene structure, chromosome distribution, phylogenetic relationship, expression pattern, and biological functions. RESULTS: We identified 34 SWEET genes in Chinese cabbage and analyzed their localization on chromosomes and transmembrane regions of their corresponding proteins...
March 2, 2018: BMC Genomics
Liming Tan, Guoai He, Feng Liu, Yunping Li, Liang Jiang
The microstructure with homogeneously distributed grains and less prior particle boundary (PPB) precipitates is always desired for powder metallurgy superalloys after hot isostatic pressing (HIPping). In this work, we studied the effects of HIPping parameters, temperature and pressure on the grain structure in PM superalloy FGH96, by means of scanning electron microscope (SEM), electron backscatter diffraction (EBSD), transmission electron microscope (TEM) and Time-of-flight secondary ion spectrometry (ToF-SIMS)...
February 24, 2018: Materials
Haihua Cao, Wei Liu, Jingcheng Xu, Jia Liu, Juwen Huang, Xiangfeng Huang, Guangming Li
Co-processing lime-dried sludge (LDS) in cement kilns is an appropriate technique to solve the problem of LDS disposal and promote the sustainable development for cement industry. However, there were limited studies that investigated the effects of feeding points on product quality and cement kiln emissions. In this study, simulated experiments were conducted by dividing the feeding points into high-temperature zones (HTZs) and raw mill (RM). Cement quality and major cement kiln emission characteristics were comprehensively investigated...
February 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
Subo Wang, Zhenhua Zhao, Hongjie Hu, Jianfeng Yang, Li Zhao, Liming Yang, Cheng Wang
OBJECTIVE: To assess the application of the dynamic-contrast enhanced magnetic resonance imaging(DCE-MRI)pharmacokinetics models in differential diagnosis of cellular uterine leiomyoma. METHODS: Sixty four patients with uterine leiomyoma confirmed by surgery and pathology were enrolled in the study between September 2015 and September 2016, including 30 cases of classical leiomyoma, 13 cases of cellular leiomyoma and 21 cases of degenerative leiomyoma. All patients underwent DCE-MRI before surgery...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
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