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Yangfeng Wu

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https://www.readbyqxmd.com/read/27772744/obesity-is-associated-with-better-survival-and-functional-outcome-after-acute-intracerebral-hemorrhage
#1
Weiping Sun, Ying Xian, Yining Huang, Wei Sun, Ran Liu, Fan Li, Jade W Wei, Ji-Guang Wang, Ming Liu, Yangfeng Wu, Lawrence K S Wong, Craig S Anderson
OBJECTIVE: To evaluate the association of obesity measured by body mass index (BMI) with mortality and functional outcome in patients with acute intracerebral hemorrhage (ICH). METHODS: Data were from 1571 patients with ICH enrolled in a national, multi-centre, prospective, hospital-based register: the ChinaQUEST (Quality Evaluation of Stroke Care and Treatment) study. The outcomes included all-cause mortality at 12months, and death or high dependency at 3 and 12months...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27753916/os-03-08-efficacy-of-telmisartan-40%C3%A2-mg-t40-and-hydrochlorothiazide-25%C3%A2-mg-h25-monotherapy-in-high-sodium-intake-patients-with-mild-to-moderate-hypertension-that-study-a-multicenter-randomized-double-blinded-parallel-controlled-trial
#2
Puhong Zhang, Ningling Sun, Hongyi Wang, Lei Sun, Jing Zhang, Yang Xi, Yangfeng Wu, Lijing Yan
OBJECTIVE: To compare the BP lowering effect of ARBs and thiazide diuretics in high sodium intake patients with mild to moderate hypertension. DESIGN AND METHOD: This research was a multicenter randomized double-blinded parallel controlled trial. Eligible participants were randomly divided into T40 and H25 groups, with 3 follow-ups, scheduled on the 15th, 30th and 60th day to compare the difference of average BP decrease, blood pressure control rates, FBG (fast blood glucose), hypokalemia and other adverse events between two groups after intervention...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753913/os-03-05-effect-of-salt-reduction-on-iodine-status-assessed-by-24%C3%A2-h-urinary-iodine-excretion-in-children-and-their-families-in-northern-china-a-cluster-randomised-controlled-trial
#3
Feng He, Yuan Ma, Xiangxian Feng, Wanqi Zhang, Laixiang Lin, Xiaohui Guo, Jing Zhang, Wenyi Niu, Yangfeng Wu, Graham MacGregor
OBJECTIVE: To study the effect of salt reduction on iodine status and to determine whether iodine consumption was still adequate after salt intake was reduced by ≈25% in northern China where universal salt iodisation is mandatory. DESIGN AND METHOD: We measured 24 h urinary iodine in individuals who participated in School-EduSalt (School-based Education Programme to Reduce Salt), a cluster randomised controlled trial in 28 primary schools (279 children, age 10...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753912/os-03-04-influence-of-family-and-peer-networks-on-salt-reduction-in-children-in-the-school-edusalt-school-based-education-programme-to-reduce-salt-trial
#4
Yuan Ma, Xiangxian Feng, Jing Zhang, Haijun Wang, Jianhui Yuan, Zhifang Li, Yanbo Han, Jianbin Zhang, Feng J He, Graham MacGregor, Yangfeng Wu
OBJECTIVE: To identify the social determinants shaping children's behaviour on salt reduction from a network perspective. DESIGN AND METHOD: School-EduSalt is a cluster-randomized controlled trial carried out in 28 primary schools in northern China involving 279 families (279 children aged 10.1 ± 0.5yrs and 553 adults). A 3.5-month education on salt reduction was delivered to the 14 schools (classes) in the intervention group, of which children and their families achieved a significant reduction in salt intake as measured by 24-hour urine sodium...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27670515/effect-of-salt-reduction-on-iodine-status-assessed-by-24%C3%A2-hour-urinary-iodine-excretion-in-children-and-their-families-in-northern-china-a-substudy-of-a-cluster-randomised-controlled-trial
#5
Feng J He, Yuan Ma, Xiangxian Feng, Wanqi Zhang, Laixiang Lin, Xiaohui Guo, Jing Zhang, Wenyi Niu, Yangfeng Wu, Graham A MacGregor
OBJECTIVE: To study the effect of salt reduction on iodine status and to determine whether iodine consumption was still adequate after salt reduction in a population where universal salt iodisation is mandatory. DESIGN: A substudy of a cluster randomised controlled trial, with schools randomly assigned to either the intervention or the control group. SETTING: 28 primary schools in Changzhi, northern China. PARTICIPANTS: 279 children in grade 5 of primary school (mean age: 10...
September 26, 2016: BMJ Open
https://www.readbyqxmd.com/read/27643280/os-03-08-efficacy-of-telmisartan-40%C3%A2-mg-t40-and-hydrochlorothiazide-25%C3%A2-mg-h25-monotherapy-in-high-sodium-intake-patients-with-mild-to-moderate-hypertension-that-study-a-multicenter-randomized-double-blinded-parallel-controlled-trial
#6
Puhong Zhang, Ningling Sun, Hongyi Wang, Lei Sun, Jing Zhang, Yang Xi, Yangfeng Wu, Lijing Yan
OBJECTIVE: To compare the BP lowering effect of ARBs and thiazide diuretics in high sodium intake patients with mild to moderate hypertension. DESIGN AND METHOD: This research was a multicenter randomized double-blinded parallel controlled trial. Eligible participants were randomly divided into T40 and H25 groups, with 3 follow-ups, scheduled on the 15th, 30th and 60th day to compare the difference of average BP decrease, blood pressure control rates, FBG (fast blood glucose), hypokalemia and other adverse events between two groups after intervention...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643261/os-03-05-effect-of-salt-reduction-on-iodine-status-assessed-by-24%C3%A2-h-urinary-iodine-excretion-in-children-and-their-families-in-northern-china-a-cluster-randomised-controlled-trial
#7
Feng He, Yuan Ma, Xiangxian Feng, Wanqi Zhang, Laixiang Lin, Xiaohui Guo, Jing Zhang, Wenyi Niu, Yangfeng Wu, Graham MacGregor
OBJECTIVE: To study the effect of salt reduction on iodine status and to determine whether iodine consumption was still adequate after salt intake was reduced by ≈25% in northern China where universal salt iodisation is mandatory. DESIGN AND METHOD: We measured 24 h urinary iodine in individuals who participated in School-EduSalt (School-based Education Programme to Reduce Salt), a cluster randomised controlled trial in 28 primary schools (279 children, age 10...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643260/os-03-04-influence-of-family-and-peer-networks-on-salt-reduction-in-children-in-the-school-edusalt-school-based-education-programme-to-reduce-salt-trial
#8
Yuan Ma, Xiangxian Feng, Jing Zhang, Haijun Wang, Jianhui Yuan, Zhifang Li, Yanbo Han, Jianbin Zhang, Feng J He, Graham MacGregor, Yangfeng Wu
OBJECTIVE: To identify the social determinants shaping children's behaviour on salt reduction from a network perspective. DESIGN AND METHOD: School-EduSalt is a cluster-randomized controlled trial carried out in 28 primary schools in northern China involving 279 families (279 children aged 10.1 ± 0.5yrs and 553 adults). A 3.5-month education on salt reduction was delivered to the 14 schools (classes) in the intervention group, of which children and their families achieved a significant reduction in salt intake as measured by 24-hour urine sodium...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27626640/impact-of-prior-use-of-four-preventive-medications-on-outcomes-in-patients-hospitalized-for-acute-coronary-syndrome-results-from-cpacs-2-study
#9
Min Li, Yubei Huang, Xin Du, Shenshen Li, Jiachao Ji, Anushka Patel, Runlin Gao, Yangfeng Wu
BACKGROUND: It is widely reported that long-term use of four preventive medications (antiplatelet agents, angiotensin converting enzyme inhibitor / angiotensin receptor blocker, statin and beta-blockers) reduce the risk of subsequent acute coronary syndromes (ACS). It is unclear whether these four medications benefit patients who develop ACS despite its use. METHODS AND RESULTS: Logistic regression and propensity-score was applied among 14790 ACS patients to assess the association between prior use of four preventive medications and in-hospital outcomes including severity of disease at presentation (type of ACS, systolic blood pressure <90 mmHg, and heart rate> = 100 beats/min), complicating arrhythmia and major adverse cardiovascular events (MACEs, including all deaths, non-fatal myocardial infarction or re-infarction, and non-fatal stroke)...
2016: PloS One
https://www.readbyqxmd.com/read/27515930/does-education-level-affect-the-efficacy-of-a-community-based-salt-reduction-program-a-post-hoc-analysis-of-the-china-rural-health-initiative-sodium-reduction-study-crhi-srs
#10
Xin Wang, Xian Li, Ilonca Vaartjes, Bruce Neal, Michiel L Bots, Arno W Hoes, Yangfeng Wu
BACKGROUND: Whether educational level influences the effects of health education is not clearly defined. This study examined whether the impact of a community-based dietary salt reduction program was affected by the level of education of participants. METHODS: The China Rural Health Initiative Sodium Reduction Study (CRHI-SRS) was a cluster-randomized controlled trial conducted in 120 villages from five Northern Chinese provinces. The intervention comprised a village-wide health education program and availability of salt substitute at village shops...
August 11, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27495056/salt-intake-belief-knowledge-and-behavior-a-cross-sectional-study-of-older-rural-chinese-adults
#11
Jing Zhang, Tao Wu, Hongling Chu, Xiangxian Feng, Jingpu Shi, Ruijuan Zhang, Yuhong Zhang, Jianxin Zhang, Nicole Li, Lijing Yan, Wenyi Niu, Yangfeng Wu
Excess sodium consumption is a major cause of high blood pressure and subsequent vascular disease. However, the factors driving people's salt intake behavior remains largely unknown. This study aims to assess the relationship of salt intake behaviors with knowledge and belief on salt and health among older adults in rural China.A cross-sectional survey was conducted among 4693 older participants (men ≥50 and women ≥60 years old) randomly selected from 120 rural villages in 5 northern provinces in China...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27462096/a-randomized-controlled-trial-on-rehabilitation-through-caregiver-delivered-nurse-organized-service-programs-for-disabled-stroke-patients-in-rural-china-the-recover-trial-design-and-rationale
#12
Lijing L Yan, Shu Chen, Bo Zhou, Jing Zhang, Bin Xie, Rong Luo, Ninghua Wang, Richard Lindley, Yuhong Zhang, Yi Zhao, Xian Li, Xiao Liu, Nicholas Peoples, Janet Prvu Bettger, Craig Anderson, Sarah E Lamb, Yangfeng Wu, Jingpu Shi
RATIONALE: Stroke is the leading cause of death and disability in rural China. For stroke patients residing in resource-limited rural areas, secondary prevention and rehabilitation are largely unavailable, and where present, are far below evidence-based standards. AIM: This study aims to develop and implement a simplified stroke rehabilitation program that utilizes nurses and family caregivers for service delivery, and evaluate its feasibility and effectiveness in rural China...
October 2016: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/27357058/relations-of-body-weight-status-in-early-adulthood-and-weight-changes-until-middle-age-with-hypertension-in-the-chinese-population
#13
Long Zhou, Ying Li, Min Guo, Yangfeng Wu, Liancheng Zhao
We conducted a retrospective cohort study of adult participants from the China Multicenter Collaborative Study of Cardiovascular Epidemiology to explore the relationship between early adulthood weight status, body weight change from age 25 to middle age and hypertension in the Chinese population. Self-reported weight was used to calculate the body mass index (BMI) at age 25. The association between BMI at age 25, subsequent weight change and hypertension was examined using a logistic regression model. Of the 14 635 study participants sampled in 1998, 3525 were diagnosed with hypertension...
June 30, 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/27297347/prevention-and-control-of-cardiovascular-disease-in-the-rapidly-changing-economy-of-china
#14
Yangfeng Wu, Emelia J Benjamin, Stephen MacMahon
With one-fifth of the world's total population, China's prevention and control of cardiovascular disease (CVD) may affect the success of worldwide efforts to achieve sustainable CVD reduction. Understanding China's current cardiovascular epidemic requires awareness of the economic development in the past decades. The rapid economic transformations (industrialization, marketization, urbanization, globalization, and informationalization) contributed to the aging demography, unhealthy lifestyles, and environmental changes...
June 14, 2016: Circulation
https://www.readbyqxmd.com/read/27102024/obesity-and-its-relation-with-diabetes-and-hypertension-a-cross-sectional-study-across-4-geographical-regions
#15
Shivani A Patel, Mohammed K Ali, Dewan Alam, Lijing L Yan, Naomi S Levitt, Antonio Bernabe-Ortiz, William Checkley, Yangfeng Wu, Vilma Irazola, Laura Gutierrez, Adolfo Rubinstein, Roopa Shivashankar, Xian Li, J Jaime Miranda, Muhammad Ashique Haider Chowdhury, Ali Tanweer Siddiquee, Thomas A Gaziano, M Masood Kadir, Dorairaj Prabhakaran
BACKGROUND: The implications of rising obesity for cardiovascular health in middle-income countries has generated interest, in part because associations between obesity and cardiovascular health seem to vary across ethnic groups. OBJECTIVE: We assessed general and central obesity in Africa, East Asia, South America, and South Asia. We further investigated whether body mass index (BMI) and waist circumference differentially relate to cardiovascular health; and associations between obesity metrics and adverse cardiovascular health vary by region...
March 2016: Global Heart
https://www.readbyqxmd.com/read/27102022/hypertension-prevalence-awareness-treatment-and-control-in-selected-lmic-communities-results-from-the-nhlbi-uhg-network-of-centers-of-excellence-for-chronic-diseases
#16
Vilma E Irazola, Laura Gutierrez, Gerald Bloomfield, Rodrigo M Carrillo-Larco, Prabhakaran Dorairaj, Thomas Gaziano, Naomi S Levitt, J Jaime Miranda, Antonio Bernabe Ortiz, Krisela Steyn, Yangfeng Wu, Denis Xavier, Lijing L Yan, Jiang He, Adolfo Rubinstein
BACKGROUND: Hypertension is the leading cause of cardiovascular disease and premature death worldwide. The prevalence of this public health problem is increasing in low- and middle-income countries (LMICs) in both urban and rural communities. OBJECTIVE: The aim of this study was to examine hypertension prevalence, awareness, treatment, and control in adults 35 to 74 years of age from urban and rural communities in LMICs in Africa, Asia, and South America. METHODS: The authors analyzed data from 7 population-based cross-sectional studies in selected communities in 9 LMICs that were conducted between 2008 and 2013...
March 2016: Global Heart
https://www.readbyqxmd.com/read/27102020/prevalence-of-pragmatically-defined-high-cv-risk-and-its-correlates-in-lmic-a-report-from-10-lmic-areas-in-africa-asia-and-south-america
#17
Rodrigo M Carrillo-Larco, J Jaime Miranda, Xian Li, Chendi Cui, Xiaolin Xu, Mohammed Ali, Dewan S Alam, Thomas A Gaziano, Rajeev Gupta, Vilma Irazola, Naomi S Levitt, Dorairaj Prabhakaran, Adolfo Rubinstein, Krisela Steyn, Nikhil Tandon, Denis Xavier, Yangfeng Wu, Lijing L Yan
BACKGROUND: Currently available tools for assessing high cardiovascular risk (HCR) often require measurements not available in resource-limited settings in low- and middle-income countries (LMIC). There is a need to assess HCR using a pragmatic evidence-based approach. OBJECTIVES: This study sought to report the prevalence of HCR in 10 LMIC areas in Africa, Asia, and South America and to investigate the profiles and correlates of HCR. METHODS: Cross-sectional analysis using data from the National Heart, Lung, and Blood Institute-UnitedHealth Group Centers of Excellence...
March 2016: Global Heart
https://www.readbyqxmd.com/read/27102019/training-and-capacity-building-in-lmic-for-research-in-heart-and-lung-diseases-the-nhlbi-unitedhealth-global-health-centers-of-excellence-program
#18
REVIEW
Gerald S Bloomfield, Denis Xavier, Deshirée Belis, Dewan Alam, Patricia Davis, Prabhakaran Dorairaj, Hassen Ghannem, Robert H Gilman, Deepak Kamath, Sylvester Kimaiyo, Naomi Levitt, Homero Martinez, Gabriela Mejicano, J Jaime Miranda, Tracey Perez Koehlmoos, Cristina Rabadán-Diehl, Manuel Ramirez-Zea, Adolfo Rubinstein, Katherine A Sacksteder, Krisela Steyn, Nikhil Tandon, Rajesh Vedanthan, Tracy Wolbach, Yangfeng Wu, Lijing L Yan
Stemming the tide of noncommunicable diseases (NCDs) worldwide requires a multipronged approach. Although much attention has been paid to disease control measures, there is relatively little consideration of the importance of training the next generation of health-related researchers to play their important role in this global epidemic. The lack of support for early stage investigators in low- and middle-income countries interested in the global NCD field has resulted in inadequate funding opportunities for research, insufficient training in advanced research methodology and data analysis, lack of mentorship in manuscript and grant writing, and meager institutional support for developing, submitting, and administering research applications and awards...
March 2016: Global Heart
https://www.readbyqxmd.com/read/26690388/exome-wide-association-analysis-reveals-novel-coding-sequence-variants-associated-with-lipid-traits-in-chinese
#19
Clara S Tang, He Zhang, Chloe Y Y Cheung, Ming Xu, Jenny C Y Ho, Wei Zhou, Stacey S Cherny, Yan Zhang, Oddgeir Holmen, Ka-Wing Au, Haiyi Yu, Lin Xu, Jia Jia, Robert M Porsch, Lijie Sun, Weixian Xu, Huiping Zheng, Lai-Yung Wong, Yiming Mu, Jingtao Dou, Carol H Y Fong, Shuyu Wang, Xueyu Hong, Liguang Dong, Yanhua Liao, Jiansong Wang, Levina S M Lam, Xi Su, Hua Yan, Min-Lee Yang, Jin Chen, Chung-Wah Siu, Gaoqiang Xie, Yu-Cho Woo, Yangfeng Wu, Kathryn C B Tan, Kristian Hveem, Bernard M Y Cheung, Sebastian Zöllner, Aimin Xu, Y Eugene Chen, Chao Qiang Jiang, Youyi Zhang, Tai-Hing Lam, Santhi K Ganesh, Yong Huo, Pak C Sham, Karen S L Lam, Cristen J Willer, Hung-Fat Tse, Wei Gao
Blood lipids are important risk factors for coronary artery disease (CAD). Here we perform an exome-wide association study by genotyping 12,685 Chinese, using a custom Illumina HumanExome BeadChip, to identify additional loci influencing lipid levels. Single-variant association analysis on 65,671 single nucleotide polymorphisms reveals 19 loci associated with lipids at exome-wide significance (P<2.69 × 10(-7)), including three Asian-specific coding variants in known genes (CETP p.Asp459Gly, PCSK9 p.Arg93Cys and LDLR p...
December 22, 2015: Nature Communications
https://www.readbyqxmd.com/read/26657005/salt-sales-survey-a-simplified-cost-effective-method-to-evaluate-population-salt-reduction-programs-a-cluster-randomized-trial
#20
Yuan Ma, Feng J He, Nicole Li, Jesse Hao, Jing Zhang, Lijing L Yan, Yangfeng Wu
Twenty-four-hour urine collection, as a gold standard method of measuring salt intake, is costly and resource consuming, which limits its use in monitoring population salt reduction programs. Our study aimed to determine whether a salt sales survey could serve as an alternative method. This was a substudy of China Rural Health Initiative-Sodium Reduction Study (CRHI-SRS), in which 120 villages were randomly allocated (1:1:2) into a price subsidy+health education (PS+HE) group, a HE-only group or a control group...
April 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
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