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https://www.readbyqxmd.com/read/29167864/hybrid-cartilage-modifying-otoplasty-technique-and-outcomes
#1
Jeffrey Markey, Jess Mace, Yvette Anderson, Tom D Wang
Importance: Otoplasty is performed to correct prominauris, one of the most common head and neck congenital deformities. Advances in combination hybrid approaches enable surgeons to achieve greater precision and accuracy. Objective: To describe a hybrid cartilage-modifying approach and evaluate the procedure's effectiveness and safety. Design, Setting, and Participants: Medical record review including patients undergoing otoplasty by the present technique from January 2006 to December 2016 as performed by the senior author at a tertiary academic referral center...
November 22, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29167620/obstructive-sleep-apnea-independently-increases-the-incidence-of-heart-failure-and-major-adverse-cardiac-events-a-retrospective-population-based-follow-up-study
#2
Yu-Sheng Lin, Pi-Hua Liu, Pao-Hsien Chu
Background: Obstructive sleep apnea (OSA) is common in heart failure (HF) patients and exacerbates the outcome of this chronic disease. However, the frequency of HF arising from OSA is varied, with little supporting literature. Here, we aimed to clarify the incidence risk of HF and major adverse cardiac events (MACEs) in OSA patients from the Taiwan large database. Methods and Results: From 2000-2010, a total of 2699 newly diagnosed OSA patients after polysomnographic study and 13,490 non-OSA patients utilizing 1:5 matching was enrolled and followed to 2011...
November 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29167614/thirty-day-and-one-year-clinical-outcomes-of-bioresorbable-vascular-scaffold-implantation-a-single-center-experience
#3
Wei-Chieh Lee, Chiung-Jen Wu, Chien-Jen Chen, Cheng-Hsu Yang, Shu-Kai Hsueh, Hon-Kan Yip, Chi-Ling Hang, Chih-Yuan Fang, Hsiu-Yu Fang
Background: Available data on the use of the Bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, CA) in real-world patients is limited, particularly in Asian populations. The aim of this study was to assess clinical outcomes of patients treated with a BVS in real-world practice in Taiwan. Methods: This study focused on 156 patients with coronary artery disease and a total of 249 lesions who received BVS implantation from October 2012 to October 2015...
November 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29166699/comparison-of-clinical-outcomes-of-coronary-artery-stent-implantation-in-patients-with-end-stage-chronic-kidney-disease-including-hemodialysis-for-three-everolimus-eluting-ees-stent-designs-bioresorbable-polymer-ees-platinum-chromium-ees-and-cobalt-chrome-ees
#4
Takao Sato, Katsuharu Hatada, Syohei Kishi, Koichi Fuse, Satoshi Fujita, Yoshio Ikeda, Minoru Takahashi, Taku Matsubara, Masaaki Okabe, Yoshifusa Aizawa
BACKGROUNDS: New-generation bioresorbable polymer-everolimus eluting stents (BP-EES) are available. This study aimed to compare the clinical outcomes for BP-EES compared to more established stent designs, namely the platinum chromium-EES (PtCr-EES) and cobalt chrome-EES(CoCr-EES) in patients with the end-stage chronic kidney disease (CKD) including hemodialysis (HD). METHODS: One-hundred-forty-one consecutive stents (BP-EES [n = 44], PtCr-EES [n = 45], and CoCr-EES [n = 52]) were implanted in 104 patients with CKD...
November 22, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29166205/pregnant-women-with-heart-disease-placental-characteristics-and-their-association-with-fetal-adverse-events
#5
Fabio V Lima, Paraskevi Koutrolou-Sotiropoulou, Puja B Parikh, Cecilia Avila, Javed Butler, Kathleen Stergiopoulos
BACKGROUND: Pregnant women with heart disease (HD) have higher rates of adverse fetal outcomes. We describe placental pathologic characteristics and their association with fetal events. METHODS: In pregnant women, known HD were categorized into: (1) cardiomyopathy (CM) or (2) other HD (congenital, coronary, arrhythmia, or valvular). Outcomes were maternal major adverse cardiac events (MACE), fetal adverse clinical events (FACE), a composite of infant death, prematurity, underweight status, intracranial hemorrhage, and respiratory distress...
November 22, 2017: Acute Cardiac Care
https://www.readbyqxmd.com/read/29165621/treatment-of-tuberculosis-in-complex-emergencies-in-developing-countries-a-scoping-review
#6
Geraldine Munn-Mace, Divya Parmar
Almost 172 million people live in complex emergencies globally resulting from political and/or economic instability. The provision and continuity of health care in complex emergencies remain a significant challenge. Health agencies are often hesitant to implement tuberculosis programmes in particular because its treatment requires a longer commitment than most acute diseases. However, not treating tuberculosis promptly increases mortality and untreated tuberculosis further increases the incidence of tuberculosis...
November 20, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29164770/clinical-outcomes-of-patients-with-coronary-artery-aneurysm-after-the-first-generation-drug-eluting-stent-implantation
#7
Hyung Joon Joo, Cheol Woong Yu, RakKyeong Choi, Jinsik Park, Hyun Jong Lee, Je Sang Kim, Young Jin Choi, Jae Hyoung Park, Soon Jun Hong, Do Sun Lim
OBJECTIVES: We sought to investigate the long-term clinical outcomes of patients with coronary artery aneurysm (CAA) after drug-eluting stent (DES) implantation, compared with patients without CAA. BACKGROUND: CAA developed after DES implantation is a rare but associated with poor clinical outcome. METHODS: We retrospectively compared 78 patients with CAA after DES implantation with 269 patients without CAA who underwent DES implantation for complex lesions (controls)...
November 22, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29164408/long-term-clinical-outcome-of-early-generation-versus-new-generation-drug-eluting-stents-in-481-patients-undergoing-rotational-atherectomy-a-retrospective-analysis
#8
Abdelhakim Allali, Erik W Holy, Dmitry S Sulimov, Ralph Toelg, Gert Richardt, Mohamed Abdel-Wahab
INTRODUCTION: New-generation drug-eluting stents (NG-DES) are superior to early generation DES (EG-DES) in the majority of lesion and patient subsets, but comparative data in patients with severely calcified coronary lesions are lacking. This study aims to compare clinical outcomes of EG-DES and NG-DES in patients undergoing rotational atherectomy (RA) in calcified lesions. METHODS: Data of 268 patients (288 lesions) treated with EG-DES and 213 patients (225 lesions) receiving NG-DES after RA were retrospectively analyzed from a single-center registry...
November 21, 2017: Cardiology and Therapy
https://www.readbyqxmd.com/read/29158058/regional-cerebral-oxygen-saturation-level-predicts-30-day-mortality-rate-after-left-ventricular-assist-device-surgery
#9
Soutik Ghosal, Jaimin Trivedi, James Chen, Michael P Rogers, Allen Cheng, Mark S Slaughter, Maiying Kong, Jiapeng Huang
OBJECTIVE: Left ventricular assist device (LVAD) surgery is complex, high risk, and expensive. The authors' hypothesis is baseline regional cerebral oxygen saturation (rSO2) might be a predictor of postoperative clinical outcomes. DESIGN: Retrospective review of 210 consecutive continuous flow LVAD patients between 2008 and 2014. The primary measure is 30-day mortality rate and secondary measures include modified major adverse cardiocerebral events (MACE), length of stay (LOS), and intensive care unit (ICU) stay...
August 19, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29155386/one-year-clinical-outcome-of-early-administration-of-intravenous-beta-blockers-in-patients-with-st-segment-elevation-myocardial-infarction-before-primary-percutaneous-coronary-reperfusion-one-year-results-from-the-early-bami-trial
#10
Vincent Roolvink, Jan Paul Ottervanger, Borja Ibáñez, Jan Henk Dambrink, Marcel Gosselink, Elvin Kedhi, Niels van Royen, Erik Lipsic, Wouter Remkes, Jan Piek, Valentin Fuster, Arnoud van 't Hof
AIMS: The EARLY-BAMI (Early intravenous beta-blockers in patients with ST-segment elevation myocardial infarction before PPCI) trial included 684 STEMI patients to iv metoprolol (2 x 5 mg bolus) or matched placebo before PPCI. One year clinical outcome was defined by major cardiac adverse event (MACE) rate, defined as cardiac death, nonfatal reinfarction, or target vessel revascularization. METHODS AND RESULTS: One year follow up was obtained in 629 patients (92%)...
November 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29155368/urinary-11-dehydro-thromboxane-b2-levels-are-associated-with-vascular-inflammation-and-prognosis-in-atherosclerotic-cardiovascular-disease
#11
Nan Wang, Kimberly C Vendrov, Brian P Simmons, Robert N Schuck, George A Stouffer, Craig R Lee
Cyclooxygenase-derived thromboxane (TxA2) and prostacyclin (PGI2) regulate atherogenesis in preclinical models. However, the relationship between TxA2 and PGI2 biosynthesis, vascular inflammation, and atherosclerotic cardiovascular disease (ASCVD) progression in humans remains unclear. The association between stable urine metabolites of thromboxane (TxA2-M) and prostacyclin (PGI2-M), circulating levels of cellular adhesion molecules (CAMs: E-selectin, P-selectin), chemokines and C-reactive protein, and the incidence of major adverse cardiovascular events (MACE) were evaluated in 120 patients with stable ASCVD on aspirin therapy...
November 16, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/29154496/research-highlights
#12
(no author information available yet)
In this issue, we highlight a study by Eng-King Tan and colleagues highlighting a role for ROS in mitophagy after Parkin translocation, a paper by Fawcett and colleagues linking the small GTPase ARF6 to integrin trafficking and axon regeneration, and a report by Lee and Mace describing the migratory behaviour of differentiating hematopoietic stem cells at single-cell resolution.
November 2017: FEBS Journal
https://www.readbyqxmd.com/read/29153919/patient-and-health-care-provider-responses-from-a-prospective-double-blind-randomized-controlled-trial-comparing-vapocoolant-spray-versus-placebo-spray-in-adults-undergoing-venipuncture-in-the-emergency-department
#13
Tracy Barbour, Sharon O'Keefe, Sharon E Mace
Painful medical procedures are common. Topical anesthetics are easily applied, rapid onset, inexpensive, and avoid injection pain and needlestick injury. The aims of this study, using patient and health care provider questionnaires, were to answer the following questions: (1) Does vapocoolant spray decrease venipuncture pain? (2) Would patients be satisfied with and use a vapocoolant spray in the future? (3) Would providers be satisfied with and use a vapocoolant spray in the future? Adults (18-80 years) in a hospital emergency department (ED) were randomly assigned to sterile water placebo spray (S) (N = 50) or vapocoolant spray (V) (N = 50) before venipuncture...
November 16, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29153576/coronary-artery-calcium-and-long-term%C3%A2-risk-of-death-myocardial%C3%A2-infarction-and-stroke-the-walter-reed-cohort-study
#14
Joshua D Mitchell, Robert Paisley, Patrick Moon, Eric Novak, Todd C Villines
OBJECTIVES: This study aimed to assess the long-term risk of death and atherosclerotic cardiovascular disease (ASCVD) outcomes, including stroke, in a real-world cohort that underwent coronary artery calcium (CAC) scoring. BACKGROUND: Large-scale, long-term studies assessing the independent relationship of CAC for prediction of ASCVD events, to include stroke, in young, low-risk patients are uncommon outside of the clinical trial setting. METHODS: A total of 23,637 consecutive subjects without ASCVD who underwent CAC scoring from 1997 to 2009 were studied...
November 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29152447/nanostructured-porous-graphene-and-its-composites-for-energy-storage-applications
#15
REVIEW
Pablo Ramos Ferrer, Annsley Mace, Samantha N Thomas, Ju-Won Jeon
Graphene, 2D atomic-layer of sp(2) carbon, has attracted a great deal of interest for use in solar cells, LEDs, electronic skin, touchscreens, energy storage devices, and microelectronics. This is due to excellent properties of graphene, such as a high theoretical surface area, electrical conductivity, and mechanical strength. The fundamental structure of graphene is also manipulatable, allowing for the formation of an even more extraordinary material, porous graphene. Porous graphene structures can be categorized as microporous, mesoporous, or macroporous depending on the pore size, all with their own unique advantages...
2017: Nano Convergence
https://www.readbyqxmd.com/read/29151360/balancing-the-playing-field-collaborative-gaming-for-physical-training
#16
Michael Mace, Nawal Kinany, Paul Rinne, Anthony Rayner, Paul Bentley, Etienne Burdet
BACKGROUND: Multiplayer video games promoting exercise-based rehabilitation may facilitate motor learning, by increasing motivation through social interaction. However, a major design challenge is to enable meaningful inter-subject interaction, whilst allowing for significant skill differences between players. We present a novel motor-training paradigm that allows real-time collaboration and performance enhancement, across a wide range of inter-subject skill mismatches, including disabled vs...
November 20, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29151138/optical-coherence-tomography-guided-percutaneous-coronary-intervention-compared-with-other-imaging-guidance-a-meta-analysis
#17
Kayode O Kuku, Emmanuel Ekanem, Viana Azizi, Gebremedhin Melaku, Anh Bui, Yael F Meirovich, Aaphtaab Dheendsa, Solomon Beyene, Alexandre Hideo-Kajita, Michael J Lipinski, Ron Waksman, Hector M Garcia-Garcia
The use of optical coherence tomography (OCT) in PCI guidance is limited perhaps by the lack of adequately powered studies which compare its efficacy and outcomes to the other more popular imaging modalities. We therefore performed a meta-analysis to compare clinical outcomes following OCT-guided PCI with the other imaging modalities in two separate comparisons. We abstracted data from randomized control trials and observational comparative studies focusing on OCT versus either angiography- or IVUS-guided PCI outcomes identified following a systematic search (April 2006 and May 2017)...
November 18, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29151032/elevated-baseline-serum-fibrinogen-effect-on-2-year-major-adverse-cardiovascular-events-following-percutaneous-coronary-intervention
#18
Lawrence Ang, Omid Behnamfar, Samhita Palakodeti, Felice Lin, Ali Pourdjabbar, Mitul P Patel, Ryan R Reeves, Ehtisham Mahmud
BACKGROUND: Elevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown. METHODS AND RESULTS: Baseline demographics and 2-year MACE were recorded among subjects undergoing nonemergent percutaneous coronary intervention. A total of 332 subjects (66.6±19.5 years, 69.9% male, 25.3% acute coronary syndrome) were enrolled. Two-year MACE (periprocedural myocardial infarction 9...
November 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29150476/predictive-value-of-apelin-12-in-patients-with-st-elevation-myocardial-infarction-with-different-renal-function-a-prospective-observational-study
#19
Lingchang Yang, Ting Zheng, Haopeng Wu, Wenwei Xin, Xiongneng Mou, Hui Lin, Yide Chen, Xiaoyu Wu
OBJECTIVES: To investigate factors predicting the onset of major adverse cardiovascular events (MACEs) after primary percutaneous coronary intervention (pPCI) for patients with ST-segment elevation myocardial infarction (STEMI) . BACKGROUND: Apelin-12 plays an essential role in cardiovascular homoeostasis. However, current knowledge of its predictive prognostic value is limited. METHODS: 464 patients with STEMI (63.0±11.9 years, 355 men) who underwent successful pPCI were enrolled and followed for 2...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29150426/long-term-outcomes-in-patients-with-type-2-myocardial-infarction-and-myocardial-injury
#20
Andrew R Chapman, Anoop S V Shah, Kuan Ken Lee, Atul Anand, Oliver Francis, Philip Adamson, David A McAllister, Fiona Strachan, David E Newby, Nicholas L Mills
Background -Type 2 myocardial infarction and myocardial injury are common in clinical practice, but long-term consequences are uncertain. We aimed to define long-term outcomes and explore risk stratification in patients with type 2 myocardial infarction and myocardial injury. Methods -We identified consecutive patients (n=2,122) with elevated cardiac troponin I concentrations (≥0.05 μg/L) at a tertiary cardiac center. All diagnoses were adjudicated as per the Universal Definition of Myocardial Infarction...
November 17, 2017: Circulation
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