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https://www.readbyqxmd.com/read/29232307/outcome-measure-scores-predict-discharge-destination-in-patients-with-acute-and-subacute-stroke-a-systematic-review-and-series-of-meta-analyses
#1
Emily R Thorpe, Katie B Garrett, Ashley M Smith, Jennifer C Reneker, Robert S Phillips
BACKGROUND AND PURPOSE: To identify the association between outcome measure score and discharge destination in adults following acute or subacute stroke in the United States. METHODS: A systematic literature search was performed in 3 databases using the PRISMA guidelines. Cohort studies were selected that included patients with acute or subacute stroke, which explored the relationship between scores on outcome measures and discharge destination. Four meta-analyses were performed...
January 2018: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29231792/patient-selection-for-mechanical-thrombectomy-in-posterior-circulation-emergent-large-vessel-occlusion
#2
Scott Raymond, Natalia Sana Rost, Pamela Whitney Schaefer, Thabele Leslie-Mazwi, Joshua A Hirsch, Ramon Gilberto Gonzalez, James Rabinov
Triage of posterior circulation stroke from emergent large-vessel occlusion (pc-ELVO) is challenging owing to the stuttering clinical course and potential for rapid decline. Growing clinical data support the use of mechanical thrombectomy in pc-ELVO, but there are limited data addressing the clinical and imaging criteria for patient selection. We present our triage algorithm used to select patients for endovascular therapy (EVT) in the setting of pc-ELVOS. We use a consecutive retrospective database from 2004 to 2016 to describe the practice patterns and prognostic factors for pc-ELVO patients treated using both medical and EVT...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29227292/association-of-hyperglycemia-systolic-and-diastolic-hypertension-and-hyperthermia-relative-to-baseline-in-the-acute-phase-of-stroke-with-poor-outcome-after-intravenous-thrombolysis
#3
Stefano Forlivesi, Nicola Micheletti, Giampaolo Tomelleri, Paolo Bovi, Manuel Cappellari
: In the acute phase of ischemic stroke, the trend of some physiological variables, such as blood glucose (BG), blood pressure, and body temperature (BT), might influence outcome. We aimed to assess the association of hyperglycemia, systolic and diastolic hypertension, and hyperthermia relative to baseline BG, systolic blood pressure, diastolic blood pressure and BT, respectively, in the first 12 h with poor outcome after intravenous thrombolysis (IVT). We conducted a retrospective analysis of data prospectively collected from 200 consecutive anterior ischemic stroke patients treated with IVT...
December 8, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29226637/the-value-of-mean-platelet-volume-for-prognosis-of-patients-with-acute-cerebral-infarction
#4
Jiao-Long Wan, Zhi-Wei Ma
BACKGROUND: The purpose of this study was to investigate the value of mean platelet volume (MPV) for prognosis of patients with acute cerebral infarction (ACI). METHODS: One hundred ACI patients and 80 healthy volunteers acting as healthy controls (HCs) were consecutively included in this study. Their baseline clinical and laboratory characteristics were extracted from an electroniccase system. ACI patients were followed for 90 days to collect the main study endpoints including poor prognosis, death due to cardiovascular causes, and the recurrence of stroke...
November 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29222905/premorbid-dietary-intake-of-protein-is-associated-with-early-outcomes-but-not-with-severity-of-ischemic-stroke
#5
Minhui Dai, Ling Tian, Wenjie Zi, Biyang Cai, Lulu Xiao, Keting Liu, Shuyu Zhou, Zhizhong Zhang, Wusheng Zhu, Fang Yang, Xinfeng Liu, Gelin Xu
BACKGROUND AND OBJECTIVES: Dietary protein intake has been associated with reduced risk of stroke. This study aimed to examine the relationship between premorbid dietary intake of protein and both stroke severity and neurological outcomes in patients with acute ischemic stroke. METHODS AND STUDY DESIGN: Consecutive patients with first-ever ischemic stroke in Jinling Hospital were screened for eligibility of participation. A validated foodfrequency questionnaire (FFQ) was performed to collect necessary data for calculating pre-stroke dietary intakes...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29222394/equivalent-favorable-outcomes-possible-after-thrombectomy-for-posterior-circulation-large-vessel-occlusion-compared-with-the-anterior-circulation-the-musc-experience
#6
Ali Alawieh, Jan Vargas, Raymond D Turner, Aquilla S Turk, M Imran Chaudry, Jonathan Lena, Alejandro Spiotta
INTRODUCTION: In acute ischemic stroke (AIS), posterior circulation large vessel occlusions (LVOs) have been associated with poorer outcomes compared with anterior circulation LVOs. The outcomes of anterior versus posterior circulation thrombectomy for LVOs were compared at a high volume center employing a direct aspiration first pass technique (ADAPT). METHODS: We retrospectively studied a database of AIS cases that underwent ADAPT thrombectomy for LVOs. Cases were grouped by anatomical location of thrombectomy (posterior vs anterior circulation), and analysis was performed on both entire sample size...
December 8, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29221777/prevalence-of-sleep-apnea-at-the-acute-phase-of-ischemic-stroke-with%C3%A2-or-without-thrombolysis
#7
Jaana K Huhtakangas, Juha Huhtakangas, Risto Bloigu, Tarja Saaresranta
OBJECTIVE: The aim of the study was to compare the prevalence, type, and severity of sleep apnea during the acute phase of ischemic stroke among patients either receiving or not receiving thrombolysis. METHODS: We recruited 246 consecutive adult ischemic stroke patients. Patients underwent cardiorespiratory sleep study with portable three-channel device during the first 48 h after the symptom onset of ischemic stroke. RESULTS: We enrolled 110 (65...
December 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29218699/clinical-outcome-of-cardioembolic-stroke-treated-by-intravenous-thrombolysis
#8
D Vaclavik, A Vilionskis, D Jatuzis, M A Karlinski, Z Gdovinova, J Kõrv, G Tsivgoulis, R Mikulik
INTRODUCTION: Cardioembolic stroke (CS) in patients without thrombolytic treatment is associated with a worse clinical outcome and higher mortality compared to other types of stroke. The aim of this study was to determine the clinical outcome of CS in patients treated by intravenous thrombolysis (IVT). MATERIAL AND METHODOLOGY: Data of patients from the SITS-EAST register (Safe Implementation of Treatments in Stroke) were analyzed in patients who received IVT treatment from 2000 to April 2014...
December 8, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29217365/alberta-stroke-program-early-ct-score-time-score-predicts-outcome-after-endovascular-therapy-in-patients-with-acute-ischemic-stroke-a-retrospective-single-center-study
#9
Kenichi Todo, Nobuyuki Sakai, Tomoyuki Kono, Taku Hoshi, Hirotoshi Imamura, Hidemitsu Adachi, Hiroshi Yamagami, Nobuo Kohara
BACKGROUND: Clinical outcomes after successful endovascular therapy in patients with acute ischemic stroke are associated with several factors including onset-to-reperfusion time (ORT), the National Institute of Health Stroke Scale (NIHSS) score, and the Alberta Stroke Program Early CT Score (ASPECTS). The NIHSS-time score, calculated as follows: [NIHSS score] × [onset-to-treatment time (h)] or [NIHSS score] × [ORT (h)], has been reported to predict clinical outcomes after intravenous recombinant tissue plasminogen activator therapy and endovascular therapy for acute stroke...
December 4, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29217362/rethinking-prehospital-stroke-notification-assessing-utility-of-emergency-medical-services-impression-and-cincinnati-prehospital-stroke-scale
#10
Stephen W English, Alejandro A Rabinstein, Jay Mandrekar, James P Klaas
BACKGROUND AND PURPOSE: Although prehospital stroke notification has improved stroke treatment, incorporation of these systems into existing infrastructure has resulted in new challenges. The goal of our study was to design an effective prehospital notification system that allows for early and accurate identification of patients presenting with acute stroke. METHODS: We conducted a retrospective single-center cohort study of patients presenting with suspicion of acute stroke from 2014 to 2015...
December 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29217361/major-adipokines-and-the-420c-g-resistin-gene-polymorphism-as-predictors-of-acute-ischemic-stroke-severity-and-in-hospital-outcome
#11
Styliani D Bouziana, Konstantinos Tziomalos, Antonios Goulas, Timoleon-Achilleas Vyzantiadis, Athanasia Panderi, Apostolos Ι Ηatzitolios
BACKGROUND: The role of adiponectin, leptin, and resistin and the -420C>G polymorphism of the resistin gene promoter in the pathogenesis of ischemic stroke are controversial. We aimed to evaluate whether serum levels of these adipokines and the -420C>G polymorphism are associated with ischemic stroke severity and in-hospital outcome. METHODS: We prospectively studied 93 patients who were consecutively hospitalized for acute ischemic stroke (39.8% males, age 79...
December 4, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29216828/factors-necessary-for-independent-walking-in-patients-with-thalamic-hemorrhage
#12
Shigenori Hiraoka, Shinichiro Maeshima, Hideto Okazaki, Hirokazu Hori, Shinichiro Tanaka, Sayaka Okamoto, Reisuke Funahashi, Kei Yagihashi, Ikuko Fuse, Naoki Asano, Shigeru Sonoda
BACKGROUND: Thalamic hemorrhages cause motor paralysis, sensory impairment, and cognitive dysfunctions, all of which may significantly affect walking independence. We examined the factors related to independent walking in patients with thalamic hemorrhage who were admitted to a rehabilitation hospital. METHODS: We evaluated 128 patients with thalamic hemorrhage (75 men and 53 women; age range, 40-93 years) who were admitted to our rehabilitation hospital. The mean duration from symptom onset to rehabilitation hospital admission was 27...
December 8, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29216218/stroke-subtype-classification-by-geometrical-descriptors-of-lesion-shape
#13
Bastian Cheng, Christian Knaack, Nils Daniel Forkert, Renate Schnabel, Christian Gerloff, Götz Thomalla
BACKGROUND AND PURPOSE: Inference of etiology from lesion pattern in acute magnetic resonance imaging is valuable for management and prognosis of acute stroke patients. This study aims to assess the value of three-dimensional geometrical lesion-shape descriptors for stroke-subtype classification, specifically regarding stroke of cardioembolic origin. METHODS: Stroke Etiology was classified according to ASCOD in retrospectively selected patients with acute stroke...
2017: PloS One
https://www.readbyqxmd.com/read/29212188/baseline-platelet-parameters-for-predicting-early-platelet-response-and-clinical-outcomes-in-patients-with-non-cardioembolic-ischemic-stroke-treated-with-clopidogrel
#14
Wenxian Li, Xiaomei Xie, Di Wei, Shijun Zhang, Yuanling Wu, Xuejun Fu, Zhen Jing, Weibiao Lu, Xinqiang Lai, Li'an Huang
Purpose: The present study investigated whether routine baseline platelet parameters(BPPs) detected before clopidogrel therapy in acute non-cardioembolic ischemic stroke(NCIS) could predict early platelet response and future clinical outcomes. Results: The CYP2C19 polymorphisms constituted independent risk factors for LCR. The number of female patients, the incidence of diabetes mellitus (DM), the level of low-density lipoprotein(LDL) cholesterol, and the neutrophil-to-lymphocyte ratio(NLR) were significantly high in the clinical clopidogrel resistance (CCR) group...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29208850/carotid-artery-stenosis-contralateral-to-acute-tandem-occlusion-an-independent-predictor-of-poor-clinical-outcome-after-mechanical-thrombectomy-with-concomitant-carotid-artery-stenting
#15
Volker Maus, Daniel Behme, Jan Borggrefe, Christoph Kabbasch, Fatih Seker, Cicek Hüseyin, Utako Birgit Barnikol, Leonard Leong Litt Yeo, Patrick Brouwer, Michael Söderman, Markus Möhlenbruch, Marios Nikos Psychogios, Thomas Liebig, Christian Dohmen, Gereon Rudolf Fink, Anastasios Mpotsaris
BACKGROUND AND PURPOSE: Cerebral ischemic strokes due to extra-/intracranial tandem occlusions (TO) of the anterior circulation are responsible for causing mechanical thrombectomy (MT). The impact of concomitant contralateral carotid stenosis (CCS) upon outcome remains unclear in this stroke subtype. METHODS: Retrospective analysis of prospectively collected data of 4 international stroke centers between 2011 and 2017. One hundred ninety-seven consecutive patients with anterior TO were treated with MT and acute carotid artery stenting (CAS)...
November 24, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29202730/selection-bias-in-clinical-stroke-trials-depending-on-ability-to-consent
#16
Benjamin Hotter, Lena Ulm, Sarah Hoffmann, Mira Katan, Joan Montaner, Alejandro Bustamante, Andreas Meisel
BACKGROUND: Clinical trials are the hallmark of evidence-based medicine, but recruitment is often challenging, especially in stroke trials investigating patients not being able to give informed consent. In some nations, ethics committees will not approve of inclusion in a clinical study via consent of a legal representative. The ethical dilemma of including or excluding those patients has not been properly addressed, as there is little data on the effect of stroke characteristics on the ability to give informed consent...
December 4, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29202727/atrial-fibrillation-is-not-uncommon-among-patients-with-ischemic-stroke-and-transient-ischemic-stroke-in-china
#17
Xiaomeng Yang, Shuya Li, Xingquan Zhao, Liping Liu, Yong Jiang, Zixiao Li, Yilong Wang, Yongjun Wang
BACKGROUND: Atrial fibrillation (AF) is reported to be a less frequent cause of ischemic stroke in China than in Europe and North America, but it is not clear whether this is due to underestimation. Our aim was to define the true frequency of AF-associated stroke, to determine the yield of 6-day Holter ECG to detect AF in Chinese stroke patients, and to elucidate predictors of newly detected AF. METHODS: Patients with acute ischemic stroke or transient ischemic attack (TIA) were enrolled in a prospective, multicenter cohort study of 6-day Holter monitoring within 7 days after stroke onset at 20 sites in China between 2013 and 2015...
December 4, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29201550/dehydration-is-a-strong-predictor-of-long-term-prognosis-of-thrombolysed-patients-with-acute-ischemic-stroke
#18
Sha-Sha Li, Ming-Ming Yin, Zhong-He Zhou, Hui-Sheng Chen
Background and Purpose: Dehydration was found to be involved in the poor prognosis of patients with acute ischemic stroke. It is unclear whether dehydration status before onset is related with prognosis of thrombolysed patients with acute ischemic stroke. If it is the case, quickly hydrating may improve the prognosis. The present study was designed to explore the issue. Methods: Eligible 294 patients with acute ischemic stroke after thrombolysis were enrolled in the present study according to inclusion/exclusion criteria...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29198948/multivariate-prognostic-model-of-acute-stroke-combining-admission-infarct-location-and-symptom-severity-a-proof-of-concept-study
#19
Seyedmehdi Payabvash, John C Benson, Andrew E Tyan, Shayandokht Taleb, Alexander M McKinney
BACKGROUND: The information on topographic distribution of acute ischemic infarct can contribute to prediction of functional outcome. We aimed to develop a multivariate model for stroke prognostication, combining admission clinical and imaging variables, including the infarct topology. METHODS: Acute ischemic stroke patients without baseline functional disability who had magnetic resonance imaging within 24 hours of onset or last-seen-well were included. The admission stroke severity was determined using the National Institutes of Health Stroke Scale (NIHSS) score...
November 29, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29198297/sleep-apnea-in-patients-hospitalized-with-acute-ischemic-stroke-underrecognition-and-associated-clinical-outcomes
#20
Nura Festic, David Alejos, Vikas Bansal, Lesia Mooney, Paul A Fredrickson, Pablo R Castillo, Emir Festic
STUDY OBJECTIVES: To evaluate clinical recognition of sleep apnea and related outcomes in patients hospitalized with acute ischemic stroke. METHODS: A retrospective study of all patients hospitalized with acute ischemic stroke from April 2008 to December 2014. The primary predictor and outcome variables were sleep apnea and hospital mortality, respectively. Secondary outcomes were mechanical ventilation, hospital length of stay, and the survivor's functional level by the modified Rankin scale...
November 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
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