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judy hung

Christos G Mihos, Romain Capoulade, Evin Yucel, Serguei Melnitchouk, Judy Hung
BACKGROUND: There is a 30-60% incidence of recurrent mitral regurgitation (MR) after mitral valve annuloplasty (Ring) for secondary MR. A concomitant papillary muscle sling (Ring+Sling) may improve valve repair by providing a more physiologic geometry of the mitral apparatus. METHODS: We retrospectively identified 58 consecutive patients with moderate-to-severe secondary MR who underwent a Ring+Sling repair, between March 2008 and May 2015. A Ring+Sling consisted of combined annuloplasty and papillary muscle approximation, utilizing a 4-mm polytetrafluoroethylene graft placed around the base of each muscle...
September 12, 2016: Journal of Cardiac Surgery
Judy Hung, Robert A Levine
No abstract text is available yet for this article.
September 8, 2016: Heart: Official Journal of the British Cardiac Society
Wuyang Yang, Jose L Porras, Alice L Hung, Syed Khalid, Tomas Garzon-Muvdi, Justin M Caplan, Maria Braileanu, Joanna Y Wang, Geoffrey P Colby, Alexander L Coon, Rafael J Tamargo, Judy Huang
Treatment selection for patients 60years of age and older with intracranial arteriovenous malformations (AVMs), requires careful consideration of the natural history and post-treatment hemorrhagic risk. We aimed to directly compare the natural history of AVMs with post-treatment hemorrhagic risk in this population. We retrospectively reviewed our AVM database of 683 patients. Patients ⩾60years at diagnosis were included. Treatment modality was divided into four groups: surgery±embolization (SE), radiosurgery±embolization (RE), embolization only (Emb), and observation (Obs)...
August 17, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Inez J Wijdh-den Hamer, Wobbe Bouma, Eric K Lai, Melissa M Levack, Eric K Shang, Alison M Pouch, Thomas J Eperjesi, Theodore J Plappert, Paul A Yushkevich, Judy Hung, Massimo A Mariani, Kamal R Khabbaz, Thomas G Gleason, Feroze Mahmood, Michael A Acker, Y Joseph Woo, Albert T Cheung, Matthew J Gillespie, Benjamin M Jackson, Joseph H Gorman, Robert C Gorman
OBJECTIVES: Repair for ischemic mitral regurgitation with undersized annuloplasty is characterized by high recurrence rates. We sought to determine the value of pre-repair 3-dimensional echocardiography over 2-dimensional echocardiography in predicting recurrence at 6 months. METHODS: Intraoperative transesophageal 2-dimensional echocardiography and 3-dimensional echocardiography were performed in 50 patients undergoing undersized annuloplasty for ischemic mitral regurgitation...
September 2016: Journal of Thoracic and Cardiovascular Surgery
James S Gammie, Peter Wilson, Krzysztof Bartus, Andrzej Gackowski, Judy Hung, Michael N D'Ambra, Piotr Kolsut, Gregory J Bittle, Piotr Szymanski, Jerzy Sadowski, Boguslaw Kapelak, Agata Bilewska, Mariusz Kusmierczyk, Mehrdad Ghoreishi
BACKGROUND: Degenerative mitral valve (MV) disease is a common cause of severe mitral regurgitation (MR) and accounts for the majority of MV operations. Conventional MV surgery requires cardiopulmonary bypass, aortic cross-clamping, cardioplegia, and a thoracotomy or sternotomy and, therefore, is associated with significant disability, risks, and unpredictable rates of MV repair. Transesophageal echocardiography-guided beating-heart MV repair with expanded polytetrafluoroethylene cordal insertion has the potential to significantly reduce surgical morbidity...
July 19, 2016: Circulation
Siew C Ng, Wai Keung Leung, Hai Yun Shi, Michael K K Li, Chi Man Leung, Carmen K M Ng, Fu Hang Lo, Yee Tak Hui, Steven W C Tsang, Yiu Kay Chan, Ching Kong Loo, Kam Hon Chan, Aric J Hui, Wai Hung Chow, Marcus Harbord, Jessica Y L Ching, Mandy Lee, Victor Chan, Whitney Tang, Ivan F N Hung, Judy Ho, Wai Cheung Lao, Marc T L Wong, Shun Fung Sze, Edwin H S Shan, Belsy C Y Lam, Raymond W H Tong, Lai Yee Mak, Sai Ho Wong, Justin C Y Wu, Francis K L Chan, Joseph J Y Sung
BACKGROUND: Incidence of inflammatory bowel disease (IBD) is increasing in Asia, but population-based prevalence data are limited. This study examined IBD incidence and prevalence based on results of a territory-wide IBD registry in Hong Kong. METHODS: We collected data on 2575 patients with IBD (1541 ulcerative colitis [UC], 983 Crohn's disease [CD], 51 IBD unclassified) from 1981 to 2014 using hospital and territory-wide administrative coding system. Prevalence and incidence, disease phenotype, surgery, and mortality were analyzed...
August 2016: Inflammatory Bowel Diseases
Timothy C Tan, Xin Zeng, Yuan Jiao, Lin Wang, Qifeng Wei, Karl Thiele, Ivan Salgo, Vipin Mehta, Michael Andrawes, Michael H Picard, Judy Hung
BACKGROUND: Assessment of mitral regurgitation (MR) severity by echocardiography is important for clinical decision making, but MR severity can be challenging to quantitate accurately and reproducibly. The accuracy of effective regurgitant orifice area (EROA) and regurgitant volume (RVol) calculated using two-dimensional (2D) proximal isovelocity surface area is limited by the geometric assumptions of proximal isovelocity surface area shape, and both variables demonstrate interobserver variability...
October 2016: Journal of the American Society of Echocardiography
Wuyang Yang, Jose L Porras, Tomas Garzon-Muvdi, Risheng Xu, Justin M Caplan, Alice L Hung, Maria Braileanu, Xiaoming Rong, Geoffrey P Colby, Alexander L Coon, Rafael J Tamargo, Judy Huang
INTRODUCTION: Management decisions for brainstem arteriovenous malformations(AVMs) are complicated by balancing the risks of treatment and natural progression to hemorrhage. The present study seeks to compare radiosurgery and conservative management outcomes in brainstem AVMs. METHODS: We performed a retrospective review of brainstem AVM patients seen at our institution from 1990-2013. Patients missing baseline information or those lost to follow-up were excluded...
June 28, 2016: World Neurosurgery
Eric L Pierce, Jean Pierre M Rabbah, Karl Thiele, Qifeng Wei, Brani Vidakovic, Morten O Jensen, Judy Hung, Ajit P Yoganathan
BACKGROUND: Accurate diagnosis of mitral regurgitation (MR) severity is central to proper treatment. Although numerous approaches exist, an accurate, gold-standard clinical technique remains elusive. The authors previously reported on the initial development and demonstration of the automated three-dimensional (3D) field optimization method (FOM) algorithm, which exploits 3D color Doppler ultrasound imaging and builds on existing MR quantification techniques. The aim of the present study was to extensively validate 3D FOM in terms of accuracy, ease of use, and repeatability...
June 25, 2016: Journal of the American Society of Echocardiography
Wuyang Yang, Heather Anderson-Keightly, Erick M Westbroek, Justin M Caplan, Xiaoming Rong, Alice L Hung, Geoffrey P Colby, Alexander L Coon, Rafael J Tamargo, Judy Huang, Edward S Ahn
OBJECTIVE Compared with the general population, the specific natural history of arteriovenous malformations (AVMs) in pediatric patients is less well understood. Furthermore, few pediatric studies have compared posttreatment hemorrhagic risk and functional outcome across different treatment modalities. The objective of this study was to elucidate these points. METHODS The authors retrospectively reviewed all pediatric patients with AVMs evaluated at their institution between 1990 and 2013. The AVM natural history was represented by hemorrhagic risk during the observation period...
September 2016: Journal of Neurosurgery. Pediatrics
Judy W S Hung, Michael W Y Leung, Clarence S W Liu, Dickson H S Fung, W L Poon, Felix S D Yam, Yvonne C L Leung, Kenneth Lap Yan Chung, Paula M Y Tang, Nicholas S Y Chao, Kelvin K W Liu
Aim Localized intravascular coagulopathy (LIC) has been described in adults with venous malformation (VM) but rarely reported in children. This study aims to determine the prevalence of LIC in children with VM and associated risk factors. Methods Patients younger than 18 years with VM from 2010 to 2014 were reviewed. Diagnosis was confirmed by Doppler ultrasound and/or magnetic resonance imaging. Demographics data and VM characteristics including volume, site, extension, painful symptoms, and palpable phleboliths were studied...
April 18, 2016: European Journal of Pediatric Surgery
Robert E Michler, Peter K Smith, Michael K Parides, Gorav Ailawadi, Vinod Thourani, Alan J Moskowitz, Michael A Acker, Judy W Hung, Helena L Chang, Louis P Perrault, A Marc Gillinov, Michael Argenziano, Emilia Bagiella, Jessica R Overbey, Ellen G Moquete, Lopa N Gupta, Marissa A Miller, Wendy C Taddei-Peters, Neal Jeffries, Richard D Weisel, Eric A Rose, James S Gammie, Joseph J DeRose, John D Puskas, François Dagenais, Sandra G Burks, Ismail El-Hamamsy, Carmelo A Milano, Pavan Atluri, Pierre Voisine, Patrick T O'Gara, Annetine C Gelijns
BACKGROUND: In a trial comparing coronary-artery bypass grafting (CABG) alone with CABG plus mitral-valve repair in patients with moderate ischemic mitral regurgitation, we found no significant difference in the left ventricular end-systolic volume index (LVESVI) or survival after 1 year. Concomitant mitral-valve repair was associated with a reduced prevalence of moderate or severe mitral regurgitation, but patients had more adverse events. We now report 2-year outcomes. METHODS: We randomly assigned 301 patients to undergo either CABG alone or the combined procedure...
May 19, 2016: New England Journal of Medicine
Irving L Kron, Michael A Acker, David H Adams, Gorav Ailawadi, Steven F Bolling, Judy W Hung, D Scott Lim, Damien J LaPar, Michael J Mack, Patrick T O'Gara, Michael K Parides, John D Puskas
No abstract text is available yet for this article.
April 2016: Journal of Thoracic and Cardiovascular Surgery
Peter M Scarbrough, Rachel Palmieri Weber, Edwin S Iversen, Yonathan Brhane, Christopher I Amos, Peter Kraft, Rayjean J Hung, Thomas A Sellers, John S Witte, Paul Pharoah, Brian E Henderson, Stephen B Gruber, David J Hunter, Judy E Garber, Amit D Joshi, Kevin McDonnell, Doug F Easton, Ros Eeles, Zsofia Kote-Jarai, Kenneth Muir, Jennifer A Doherty, Joellen M Schildkraut
BACKGROUND: DNA damage is an established mediator of carcinogenesis, although genome-wide association studies (GWAS) have identified few significant loci. This cross-cancer site, pooled analysis was performed to increase the power to detect common variants of DNA repair genes associated with cancer susceptibility. METHODS: We conducted a cross-cancer analysis of 60,297 single nucleotide polymorphisms, at 229 DNA repair gene regions, using data from the NCI Genetic Associations and Mechanisms in Oncology (GAME-ON) Network...
January 2016: Cancer Epidemiology, Biomarkers & Prevention
Daniel Goldstein, Alan J Moskowitz, Annetine C Gelijns, Gorav Ailawadi, Michael K Parides, Louis P Perrault, Judy W Hung, Pierre Voisine, Francois Dagenais, A Marc Gillinov, Vinod Thourani, Michael Argenziano, James S Gammie, Michael Mack, Philippe Demers, Pavan Atluri, Eric A Rose, Karen O'Sullivan, Deborah L Williams, Emilia Bagiella, Robert E Michler, Richard D Weisel, Marissa A Miller, Nancy L Geller, Wendy C Taddei-Peters, Peter K Smith, Ellen Moquete, Jessica R Overbey, Irving L Kron, Patrick T O'Gara, Michael A Acker
BACKGROUND: In a randomized trial comparing mitral-valve repair with mitral-valve replacement in patients with severe ischemic mitral regurgitation, we found no significant difference in the left ventricular end-systolic volume index (LVESVI), survival, or adverse events at 1 year after surgery. However, patients in the repair group had significantly more recurrences of moderate or severe mitral regurgitation. We now report the 2-year outcomes of this trial. METHODS: We randomly assigned 251 patients to mitral-valve repair or replacement...
January 28, 2016: New England Journal of Medicine
Wuyang Yang, Ann Liu, Alice L Hung, Maria Braileanu, Joanna Y Wang, Justin M Caplan, Geoffrey P Colby, Alexander L Coon, Rafael J Tamargo, Edward S Ahn, Judy Huang
BACKGROUND: Patients diagnosed with hereditary hemorrhagic telangiectasia (HHT) are at risk of developing intracranial arteriovenous malformations (AVM). However, the clinical manifestations and natural history of HHT-related AVMs remain unclear due to the rarity of these lesions. OBJECTIVE: To clarify the clinical characteristics and hemorrhagic risk in HHT-related AVMs. METHODS: We performed a retrospective review of all patients diagnosed with both HHT and intracranial AVMs who were evaluated at our institution from 1990 to 2013...
May 2016: Neurosurgery
Timothy C Tan, Judy W Hung
The mitral valve is the most commonly diseased heart valve and the prevalence of mitral valve disease increases proportionally with age. Echocardiography is the primary diagnostic imaging modality used in the assessment of patients with mitral valve disease. It is a noninvasive method which provides accurate anatomic and functional information regarding the mitral valve and can identify the mechanism of mitral valve pathology. This is especially useful as it may guide surgical repair. This is increasingly relevant given the growing trend of patients undergoing mitral valve repair...
September 2015: Annals of Cardiothoracic Surgery
Vincent Wai-Sun Wong, Grace Lai-Hung Wong, Judy Ching-Lam Yeung, Chloe Yuk-Kiu Fung, Jasmine Ka-Lei Chan, Zoe Hoi-Yi Chang, Chelsia Tsz-Yan Kwan, Hiu-Wan Lam, Jenny Limquiaco, Angel Mei-Ling Chim, Cheuk-Man Yu, Henry Lik-Yuen Chan
UNLABELLED: There is ongoing debate on whether screening for nonalcoholic fatty liver disease (NAFLD) is worthwhile in high-risk groups. Because of shared risk factors, NAFLD is highly prevalent in patients with coronary artery disease. We aimed to test the hypothesis that NAFLD screening in patients requiring coronary angiogram would identify high-risk patients and predict long-term clinical outcomes. This was a prospective cohort study. NAFLD screening was performed by abdominal ultrasonography before coronary angiogram in 612 consecutive patients...
March 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
Rosanna Beraldi, Chun-Hung Chan, Christopher S Rogers, Attila D Kovács, David K Meyerholz, Constantin Trantzas, Allyn M Lambertz, Benjamin W Darbro, Krystal L Weber, Katherine A M White, Richard V Rheeden, Michael C Kruer, Brian A Dacken, Xiao-Jun Wang, Bryan T Davis, Judy A Rohret, Jason T Struzynski, Frank A Rohret, Jill M Weimer, David A Pearce
Ataxia telangiectasia (AT) is a progressive multisystem disorder caused by mutations in the AT-mutated (ATM) gene. AT is a neurodegenerative disease primarily characterized by cerebellar degeneration in children leading to motor impairment. The disease progresses with other clinical manifestations including oculocutaneous telangiectasia, immune disorders, increased susceptibly to cancer and respiratory infections. Although genetic investigations and physiological models have established the linkage of ATM with AT onset, the mechanisms linking ATM to neurodegeneration remain undetermined, hindering therapeutic development...
November 15, 2015: Human Molecular Genetics
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