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Chronic dissection

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https://www.readbyqxmd.com/read/29160090/two-consecutive-cases-of-persistent-stapedial-artery-managed-with-a-carbon-dioxide-laser
#1
Shawn M Stevens, Zoe A Walters, Kareem Tawfik, Ravi N Samy
OBJECTIVE: (1) Discuss the presentation and management of persistent stapedial artery (PSA) discovered incidentally during cholesteatoma surgery. (2) Review use of carbon dioxide (CO2) laser for treatment of PSA in the setting of chronic ear disease. PATIENTS: Two consecutive patients with PSA and primary acquired cholesteatoma. INTERVENTION(S): Tympanomastoidectomy using a canal wall reconstruction technique. MAIN OUTCOME MEASURE(S): Surgical healing, collateral damage to surrounding anatomy, and postoperative hearing...
November 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29157682/outcomes-of-thoracic-endovascular-aortic-repair-for-chronic-aortic-dissections
#2
Allan M Conway, Khalil Qato, Laurie R Mondry, Guillaume J Stoffels, Gary Giangola, Alfio Carroccio
BACKGROUND: Open surgical repair remains the "gold standard" treatment for chronic type B aortic dissection (cTBD) with aneurysm. Thoracic endovascular aortic repair (TEVAR) has gained popularity in recent years for the treatment of thoracic aortic diseases, including cTBD. We assessed the effectiveness of TEVAR in the treatment of cTBD using the Vascular Quality Initiative (VQI) database. METHODS: The VQI registry identified 4713 patients treated with TEVAR from July 2010 to November 2015, including 125 repairs for cTBD...
November 17, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29155940/stented-balloon-fenestration-before-entry-repair-using-the-frozen-elephant-trunk-technique-for-chronic-aortic-dissection
#3
Naomichi Uchida, Yoshitaka Yamane, Tomokuni Furukawa
Endovascular fenestration on the abdominal aorta is effective for preventing visceral malperfusion in aortic dissection. We report a case of stented balloon fenestration before residual entry repair using the frozen elephant trunk technique for chronic aneurysmal dissection after ascending aortic replacement for DeBakey I aortic dissection. We recognized poor communication between the true lumen and false lumen in the abdominal aorta, and visceral perfusion depended almost entirely on the proximal large entry...
October 9, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29153807/thoracic-endovascular-aortic-repair-using-vascular-plug-for-chronic-type-iiib-aortic-dissection
#4
Up Huh, Seunghwan Song, Eunji Kim, Chang Won Kim
A 72-year-old man previously treated for an abdominal aortic aneurysm (AAA) was diagnosed with the 70-mm-sized type IIIb aortic dissection. Endovascular repair was considered, but there was no stent graft passing through the 8-mm iliac graft that was used for open repair of the AAA. We sealed the 5-mm-sized intimal tear site, using an Amplatzer Vascular Plug, which successfully repaired. The patient was discharged and had no complications. Serial follow-up computerized tomography scans showed that the vascular plug was positioned without migration, and the size of the aorta decreased...
December 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29153441/complex-endovascular-repair-of-postdissection-arch-and-thoracoabdominal-aneurysms
#5
Rafaëlle Spear, Adrien Hertault, Katrien Van Calster, Nicla Settembre, Matthieu Delloye, Richard Azzaoui, Jonathan Sobocinski, Dominique Fabre, Mark Tyrrell, Stéphan Haulon
OBJECTIVE: We report our experience of the treatment of postdissection arch aneurysms and thoracoabdominal aortic aneurysms (TAAAs) by endovascular repair using fenestrated and branched endografts. METHODS: This study includes all patients presenting with chronic postdissection aneurysms >55 mm in diameter deemed unfit for open surgery and treated by complex endografting between October 2011 and April 2017. Where appropriate, staged management strategies including left subclavian artery revascularization, thoracic endografting, dissection flap fenestration, and tear enlargement were performed before the complex endovascular repair...
November 15, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29151155/intraurethral-injection-with-lps-an-effective-experimental-model-of-prostatic-inflammation
#6
Fabiana Oliveira Dos Santos Gomes, Amanda Costa Oliveira, Edlene Lima Ribeiro, Bruna Santos da Silva, Laise Aline Martins Dos Santos, Ingrid Tavares de Lima, Amanda Karolina Soares E Silva, Shyrlene Meiry da Rocha Araújo, Terezinha Gonçalves, Mario Ribeiro de Melo-Junior, Christina Alves Peixoto
OBJECTIVE: Chronic inflammation has been recognized as having a prominent role pathogenesis of benign prostatic hyperplasia (BPH) and cancer. It is believed that chronic inflammation induces prostatic fibromuscular growth. This correlation has been clearly illustrated by both in vivo and in vitro studies; however, current experimental models of BPH require complex surgery or hormonal treatment. Therefore, the aim of the present study was to propose a new murine model of BPH/prostatitis induced by intraurethral injection of LPS...
November 18, 2017: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/29147485/the-effects-of-anti-fas-ribozyme-on-t-lymphocyte-apoptosis-in-mice-model-with-chronic-obstructive-pulmonary-disease
#7
Song-Ming Zhuo, Si-Cong Li, Yong-Qun Lin, Hai-Bin Yu, Na Li
Objectives: In this study, we aimed to investigate the effects of anti-Fas ribozyme on the apoptosis of T lymphocytes (T cells) in mice model with chronic obstructive pulmonary disease (COPD). Materials and Methods: Male 6-week-old C57BL/6 mice were used to establish the COPD model by exposure to cigarette smoke. The COPD mice were sacrificed for spleen dissection and T cell isolation. T cells were randomly divided into four groups (n=10 per group). Group A was used as the control...
October 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29147475/an-extensive-chronic-aortic-dissection-presenting-with-acute-embolic-stroke
#8
Sijan Basnet, Naba Raj Mainali, Biswaraj Tharu, Rashmi Dhital, Dilli Ram Poudel
Herein, we present a rare case of extensive chronic aortic dissection with extension to bilateral subclavian arteries, bilateral common carotid arteries, right internal carotid artery, bilateral proximal external iliac arteries and simultaneous presentation of acute embolic stroke and seizure. The rarity of this case presentation and the presence of neurological features necessitated a high index of clinical suspicion to reach the definitive diagnosis. This study also demonstrates a unique situation requiring correlation between chronic aortic dissection and multi-organ system dysfunction from chronic ischemia...
2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29141219/preventive-inhibition-of-liver-tumorigenesis-by-systemic-activation-of-innate-immune-functions
#9
Jin Lee, Rui Liao, Gaowei Wang, Bi-Huei Yang, Xiaolin Luo, Nissi M Varki, Shuang-Jian Qiu, Bing Ren, Wenxian Fu, Gen-Sheng Feng
Liver cancer has become the second most deadly malignant disease, with no efficient targeted or immune therapeutic agents available yet. While dissecting the roles of cytoplasmic signaling molecules in hepatocarcinogenesis using an inducible mouse gene targeting system, Mx1-cre, we identified a potent liver tumor-inhibitory effect of synthetic double-stranded RNA (dsRNA), polyinosinic-polycytidylic acid (pIC), an inducer of the Mx1-cre system. Injection of pIC at the pre-cancer stage robustly suppressed liver tumorigenesis either induced by chemical carcinogens or by Pten loss and associated hepatosteatosis...
November 14, 2017: Cell Reports
https://www.readbyqxmd.com/read/29140572/dissecting-human-ilc-heterogeneity-more-than-just-three-subsets
#10
REVIEW
Yannick Simoni, Evan W Newell
Innate lymphoid cells (ILCs) have been divided into three distinct groups based on functional capacities, cytokine profiles and transcription factor expression. Studies done mostly in mice have demonstrated the importance of ILCs in chronic inflammation, infection, allergy and cancer. In this review, we discuss the heterogeneity of human ILC and focus primarily on the taxonomy of human ILC cell subsets and their phenotypic and functional diversity. We summarize recent findings about the diversity of ILCs between and within the major subsets (NK, ILC1, ieILC1, ILC2, ILC3, LTi, ILCP), as well as the abundance of each in human tissues...
November 15, 2017: Immunology
https://www.readbyqxmd.com/read/29138365/one-year-clinical-outcomes-of-the-hybrid-cto-revascularization-strategy-after-hospital-discharge-a-subanalysis-of-the-multicenter-recharge-registry
#11
Joren Maeremans, Alexandre Avran, Simon Walsh, Paul Knaapen, Colm G Hanratty, Benjamin Faurie, Pierfrancesco Agostoni, Erwan Bressollette, Peter Kayaert, Dave Smith, Alexander Chase, Margaret B Mcentegart, William H T Smith, Alun Harcombe, John Irving, Andrew Ladwiniec, James C Spratt, Jo Dens
OBJECTIVES: Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) has historically been associated with higher event rates during follow-up. The hybrid algorithm and contemporary wiring and dissection re-entry (DR) techniques can potentially improve long-term outcomes after CTO-PCI. This study assessed the long-term clinical outcomes of the hybrid CTO practice, when applied by operators with varying experience levels. METHODS: We examined the 1-year clinical events after hospital discharge of the RECHARGE population, according to technical outcome and final technique...
November 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29137226/the-neglected-avian-hepatotropic-virus-induces-acute-and-chronic-hepatitis-in-ducks-an-alternative-model-for-hepatology
#12
Xumin Ou, Sai Mao, Jingyu Cao, Yunchao Ma, Guangpeng Ma, Anchun Cheng, Mingshu Wang, Dekang Zhu, Shun Chen, Renyong Jia, Mafeng Liu, Kunfeng Sun, Qiao Yang, Ying Wu, Xiaoyue Chen
Duck Hepatitis A Virus (DHAV) belongs to the Avihepatovirus, which is also classified into Picornaviridae with Hepatovirus, Hepatitis A Virus (HAV). In humans, the pathogenesis of HAV is not well understood because of limited work with animal models. Here, we investigated the progress of duck viral hepatitis caused by DHAV and their potential for dissecting the pathogenesis of HAV. During the course of infection, the duck model had undergone hepatocellular lesions (vacuolation, acidophilic degeneration and steatosis), lymphocytes recruitment (neutrophil granulocytes, heterophilic granulocytes and T cells or plasm cells) and repair (activation of hepatic stellate cells, fibrosis and regeneration)...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29129854/update-on-the-therapeutic-strategy-of-type-b-aortic-dissection
#13
Shuichiro Kaji
Stanford type B aortic dissection (TBAD) is a life-threatening disease. Current therapeutic guidelines recommend medical therapy with aggressive blood pressure lowering for patients with acute TBAD unless they have fatal complications. Although patients with uncomplicated TBAD have relatively low early mortality, aorta-related adverse events during the chronic phase worsen the long-term clinical outcome. Recent advances in thoracic endovascular aortic repair (TEVAR) can improve clinical outcomes in patients with both complicated and uncomplicated TBAD...
November 10, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29129420/surgical-strategy-for-the-treatment-of-aortoesophageal-fistula
#14
Takahiro Yamazato, Tetsu Nakamura, Noriyuki Abe, Koki Yokawa, Yuki Ikeno, Yojiro Koda, Soichiro Henmi, Hidekazu Nakai, Yasuko Gotake, Takashi Matsueda, Takeshi Inoue, Hiroshi Tanaka, Yoshihiro Kakeji, Yutaka Okita
OBJECTIVE: To present a surgical strategy for aortoesophageal fistula (AEF). METHODS: From October 1999 to May 2017, 27 patients with AEF were treated at Kobe University Hospital. After 9 patients with malignancies or fish bone penetration were excluded, 18 patients who had AEF secondary to aortic lesions were investigated. The mean age was 67.2 ± 10.4 years, and the male/female ratio was 16:2. Twelve patients had a nondissection thoracic aneurysm, and 6 patients had a chronic aortic dissection...
September 20, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29124663/residual-flow-in-false-lumen-of-chronic-descending-aortic-dissection
#15
M Boulaksil, S S Liem, M Akarkach, J Timmermans
No abstract text is available yet for this article.
November 9, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29122129/a-new-algorithm-for-crossing-chronic-total-occlusions-from-the-asia-pacific-chronic-total-occlusion-club
#16
REVIEW
Scott A Harding, Eugene B Wu, Sidney Lo, Soo Teik Lim, Lei Ge, Ji-Yan Chen, Jie Quan, Seung-Whan Lee, Hsien-Li Kao, Etsuo Tsuchikane
Although the hybrid chronic total occlusion (CTO) algorithm had many excellent recommendations, there has been infrequent adoption in the Asia Pacific region. The Asia Pacific CTO club propose an algorithm for case selection based on the Japan-CTO score and a new CTO algorithm, which is applicable globally. This algorithm allows for differing skill sets and equipment availability and contains practical teaching for CTO percutaneous coronary intervention. Similar to the hybrid algorithm there are 3 main questions that determine whether the primary approach is antegrade or retrograde: 1) is there proximal cap ambiguity; 2) is the distal vessel of poor quality; and 3) are there interventional collaterals present...
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29120031/histopathological-immunohistochemical-and-stereological-analysis-of-the-effect-of-gingko-biloba-egb761-on-the-hippocampus-of-rats-exposed-to-long-term-cellphone-radiation
#17
Fikret Gevrek
Cellular phones are major sources of electromagnetic radiation (EMR) that can penetrate the human body and pose serious health hazards. The increasingly widespread use of mobile communication systems has raised concerns about the effects of cellphone radiofrequency (RF) on the hippocampus because of its close proximity to radiation during cellphone use. The effects of cellphone EMR exposure on the hippocampus of rats and the possible counteractive effects of ginkgo biloba (Egb761) were aimed to investigate...
November 9, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/29118517/dissecting-cellulitis-of-the-scalp-early-diagnosed-by-color-doppler-ultrasound
#18
Karina Cataldo-Cerda, Ximena Wortsman
Dissecting cellulitis of the scalp (DC) is a chronic inflammatory condition of the scalp that ultimately leads to scarring alopecia. A healthy 19-year-old male presented with a solitary, soft, alopecic nodule that had appeared 1 year before. A color Doppler ultrasound examination showed a hypodermal anechoic fluid collection in the left parietotemporal region of the scalp, connected to the base of widened hair follicles, and presented inner echoes suggestive of debris, as well as several fragments of hair tracts...
October 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/29115411/transcriptome-sequencing-revealed-candidate-genes-relevant-to-mesenchymal-stem-cells-role-in-aortic-dissection-patients
#19
Junlin Yang, Sili Zou, Mingfang Liao, Lefeng Qu
Aortic dissection (AD) results from the imbalance between synthesis and degradation of extracellular matrices in aortic wall, which is characterized by chronic inflammation. Mesenchymal stem cells (MSCs) are known for anti‑inflammatory and repairing effects and have therefore been studied for treatment for numerous diseases, including AD. However, it is unclear which genes or signaling pathways contribute to MSCs' role in AD. In the present study, RNA sequencing (RNA‑seq) was conducted between MSCs from patients with AS (AD‑MSCs) and those from age‑matched healthy donors (HD‑MSCs)...
October 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29110635/a-modified-endoscopic-submucosal-dissection-for-a-superficial-hypopharyngeal-cancer-a-case-report-and-technical-discussion
#20
Lianjun Di, Kuang-I Fu, Rui Xie, Xinglong Wu, Youfeng Li, Huichao Wu, Biguang Tuo
BACKGROUND: Adequate working space and a clear view for the dissected lesion are crucial for endoscopic submucosal dissection (ESD). Pharyngeal ESD requires that an otorhinolaryngologist creates working space by lifting the larynx with a curved laryngoscope. However, many countries do not have this kind of curved laryngoscope, and the devices could interfere with endoscope because of the narrow space of the pharynx. To overcome these issues, we used a transparent hood (Elastic Touch, slit and hole type, M (long), Top company, Tokyo Japan) instead of the curved laryngoscope to create adequate working space by pushing the larynx, and pharyngeal ESD could be done by gastroenterologists...
November 6, 2017: BMC Cancer
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