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https://www.readbyqxmd.com/read/27894713/abdominal-aortic-aneurysm-in-marfan-syndrome
#1
Tracy Hagerty, Patrick Geraghty, Alan C Braverman
OBJECTIVE: Marfan syndrome (MFS) leads to aortic root aneurysm, while descending thoracic aortic aneurysm (TAA) occurs less commonly. Abdominal aortic aneurysm (AAA) is rarely reported in MFS. Risk factors for AAA are poorly understood and there are no guidelines for AAA screening in MFS. We sought to characterize AAA among Marfan patients in our center. METHODS: The records of 12 adults with MFS and AAA disease were reviewed. Clinical features, imaging, operative reports, and outcomes were analyzed...
November 25, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27890849/hybrid-treatment-of-a-suprarenal-aortic-aneurysm-with-an-infrarenal-aorto-bifemoral-surgical-graft-and-a-fenestrated-stent-graft
#2
Sebastian Nagel, Athanasios Katsargyris, Kyriakos Oikonomou, Eric L G Verhoeven
PURPOSE: To report a hybrid technique for the treatment of a suprarenal aortic aneurysm (SAA) in a patient with iliac occlusive disease. Initially an infrarenal aorto-bifemoral surgical graft was implanted, followed by deployment of a fenestrated bifurcated stent-graft at the suprarenal part of the aorta. CASE REPORT: A 69-year old man presented with a 51-mm saccular SAA and iliac occlusive disease with intermittent claudication. Both common iliac arteries had been previously treated with kissing stents...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27890835/acute-kidney-injury-after-open-repair-of-intact-abdominal-aortic-aneurysms
#3
REVIEW
Charles Dariane, Raphaël Coscas, Celia Boulitrop, Isabelle Javerliat, Eve Vilaine, Olivier Goeau-Brissonniere, Marc Coggia, Ziad A Massy
BACKGROUND: These last years, considerable attention has been given to renal issues following endovascular aortic repair (EVAR) but acute kidney injury (AKI) also remains one of the most frequent complications following open repair (OR). OBJECTIVES: Since AKI definition has evolved, our aim was to review the aetiology, incidence, classifications and consequences of AKI after OR for intact abdominal aortic aneurysm (AAA). METHODS: A review of the English language literature published between 2004 and 2016 was conducted according to the PRISMA criteria...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27890833/pulse-wave-analysis-after-treatment-of-abdominal-aortic-aneurysms-with-the-ovation-device
#4
Efstratios Georgakarakos, Christos Argyriou, George S Georgiadis, Miltos K Lazarides
BACKGROUND: Ovation Aortic Stent-Graft System is a new device for the endovascular treatment of Abdominal Aortic Aneurysms achieving fixation via a 35-mm long, rigid ancored suprarenal stent and sealing stent at the infrarenal level by a means of a polymer-filling pair of inflatable O-rings which cause narrowing of flow lumen and regional stenosis. Thus, concerns have been raised regarding hemodynamic consequences associated with this new desing . Our preliminary report showed no significant increase of aortic pulse wave velocity (aPWV) immediately after implantation of the Ovation in 3 patients...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27866882/commentary-on-the-endovascular-sealing-device-in-combination-with-parallel-grafts-for-treatment-of-juxta-suprarenal-abdominal-aortic-aneurysms-short-term-results-of-a-novel-alternative
#5
M Knowles, C Timaran
No abstract text is available yet for this article.
November 17, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27769755/noninvasive-regional-aortic-stiffness-for-monitoring-the-early-stage-of-abdominal-aortic-aneurysm-in-mice
#6
Qiulun Lu, Xiuxin Jiang, Cheng Zhang, Wei Zhang, Wencheng Zhang
BACKGROUND: Abdominal aortic aneurysm (AAA) affects more than 5% of the population in developed countries. To study the formation and progression of AAA, we developed a non-invasive method to analyse regional aortic stiffness to monitor the formation and progression of AAA. METHODS: Saline or Angiotensin II (AngII) was subcutaneously infused in apolipoprotein E knockout (ApoE(-/-)) mice for 28 days; a high-resolution imaging system was used to identify changes in arterial stiffness measured by pulse-wave velocity (PWV) and aortic lumen diameter in the suprarenal aorta...
August 17, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27767064/angiopoietin-2-attenuates-angiotensin-ii-induced-aortic-aneurysm-and-atherosclerosis-in-apolipoprotein-e-deficient-mice
#7
Hongyou Yu, Corey S Moran, Alexandra F Trollope, Lynn Woodward, Robert Kinobe, Catherine M Rush, Jonathan Golledge
Angiogenesis and inflammation are implicated in aortic aneurysm and atherosclerosis and regulated by angiopoietin-2 (Angpt2). The effect of Angpt2 administration on experimental aortic aneurysm and atherosclerosis was examined. Six-month-old male apolipoprotein E deficient (ApoE(-/-)) mice were infused with angiotensin II (AngII) and administered subcutaneous human Fc-protein (control) or recombinant Angpt2 (rAngpt2) over 14 days. Administration of rAngpt2 significantly inhibited AngII-induced aortic dilatation and rupture of the suprarenal aorta (SRA), and development of atherosclerosis within the aortic arch...
October 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27720319/a-multicenter-experience-with-infected-abdominal-aortic%C3%A2-endograft-explantation
#8
Xavier Chaufour, Julien Gaudric, Yann Goueffic, Réda Hassen Khodja, Patrick Feugier, Sergei Malikov, Guillaume Beraud, Jean-Baptiste Ricco
OBJECTIVE: Endovascular aneurysm repair (EVAR) is widely used with excellent results, but its infectious complications can be devastating. In this paper, we report a multicenter experience with infected EVAR, symptoms, and options for explantation and their outcome. METHODS: We have reviewed all consecutive endograft explants for infection at 11 French university centers following EVAR, defined as index EVAR, from 1998 to 2015. Diagnosis of infected aortic endograft was made on the basis of clinical findings, cultures, imaging studies, and intraoperative findings...
October 5, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27650558/age-associated-sirtuin-1-reduction-in-vascular-smooth-muscle-links-vascular-senescence-and-inflammation-to-abdominal-aortic-aneurysm
#9
Hou-Zao Chen, Fang Wang, Peng Gao, Jian-Fei Pei, Yue Liu, Ting-Ting Xu, Xiaoqiang Tang, Wen-Yan Fu, Jie Lu, Yun-Fei Yan, Xiao-Man Wang, Lei Han, Zhu-Qin Zhang, Ran Zhang, Ming-Hui Zou, De-Pei Liu
RATIONALE: Uncontrolled growth of abdominal aortic aneurysms (AAAs) is a life-threatening vascular disease without an effective pharmaceutical treatment. AAA incidence dramatically increases with advancing age in men. However, the molecular mechanisms by which aging predisposes individuals to AAAs remain unknown. OBJECTIVE: In this study, we investigated the role of SIRT1 (Sirtuin 1), a class III histone deacetylase, in AAA formation and the underlying mechanisms linking vascular senescence and inflammation...
October 28, 2016: Circulation Research
https://www.readbyqxmd.com/read/27603002/combined-epidural-general-anesthesia-vs-general-anesthesia-alone-for-elective-abdominal-aortic-aneurysm-repair
#10
Amit Bardia, Akshay Sood, Feroze Mahmood, Vwaire Orhurhu, Ariel Mueller, Mario Montealegre-Gallegos, Marc R Shnider, Klaas H J Ultee, Marc L Schermerhorn, Robina Matyal
Importance: Epidural analgesia (EA) is used as an adjunct procedure for postoperative pain control during elective abdominal aortic aneurysm (AAA) surgery. In addition to analgesia, modulatory effects of EA on spinal sympathetic outflow result in improved organ perfusion with reduced complications. Reductions in postoperative complications lead to shorter convalescence and possibly improved 30-day survival. However, the effect of EA on long-term survival when used as an adjunct to general anesthesia (GA) during elective AAA surgery is unknown...
September 7, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27575811/repeated-contrast-medium-application-after-endovascular-aneurysm-repair-and-not-the-type-of-endograft-fixation-seems-to-have-deleterious-effect-on-the-renal-function
#11
Daphne Elisabeth Gray, Markus Eisenack, Michael Gawenda, Giovanni Torsello, Payman Majd, Jan Brunkwall, Nani Osada, Konstantinos P Donas
OBJECTIVE: The influence of endovascular aneurysm repair (EVAR) on renal function is of high concern. The question whether stent graft fixation type plays a significant role in renal outcome after EVAR is still debated. However, other factors, such as repeated contrast medium exposure, should also be considered. METHODS: We performed a two-center, stratified-cohort case control study to evaluate the influence of last-generation abdominal endografts with suprarenal (SR) vs infrarenal (IR) fixation on renal function...
August 26, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27573021/operative-and-midterm-outcomes-of-the-fenestrated-anaconda-stent-graft-in-the-endovascular-treatment-of-juxtarenal-suprarenal-and-type-iv-thoracoabdominal-aortic-aneurysms
#12
Drosos Kotelis, Karina Schleimer, Houman Jalaie, Jochen Grommes, Michael J Jacobs, Johannes Kalder
PURPOSE: To report operative and midterm outcomes of fenestrated endovascular aneurysm repair (FEVAR) with the Anaconda device. METHODS: A retrospective analysis was conducted of 39 consecutive patients (median age 74 years; 36 men) treated with the fenestrated Anaconda stent-graft between July 2011 and December 2015 at a single center. Indications for FEVAR were abdominal aortic aneurysms (AAAs) with neck anatomy unsuitable for a standard stent-graft. Median infrarenal neck length was 4 mm (range 0-9)...
August 29, 2016: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/27545668/sonographic-changes-in-optic-nerve-sheath-diameter-associated-with-supra-versus-infrarenal-aortic-aneurysm-repair
#13
Michael Ertl, Wilma Schierling, Piotr M Kasprzak, Reinhard Kopp, Corinna Brückl, Felix Schlachetzki, Karin Pfister
BACKGROUND AND PURPOSE: Quantification of changes in optic nerve sheath diameter (ONSD) using ocular sonography (OS) constitutes an elegant technique for estimating intracranial and intraspinal pressure. Aortic aneurysm repair (AAR) is associated with a reasonable risk of increased spinal fluid pressure, which is largely dependent on the extent of aneurysm repair (supra- vs. infrarenal). The aim of this study was to compare ONSD measurements in patients with suprarenal AAR (sAAR) or infrarenal AAR (iAAR)...
August 22, 2016: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/27527570/the-endovascular-sealing-device-in-combination-with-parallel-grafts-for-treatment-of-juxta-suprarenal-abdominal-aortic-aneurysms-short-term-results-of-a-novel-alternative
#14
J L De Bruin, J R Brownrigg, B O Patterson, A Karthikesalingam, P J Holt, R J Hinchliffe, I M Loftus, M M Thompson
BACKGROUND: The chimney technique using parallel grafts offers an alternative to fenestrated or branched endovascular solutions for juxtarenal and suprarenal aneurysms. Endograft deployment proximal to the renal or visceral ostia is combined with parallel stents to the aortic side branches. Application of the chimney technique using the Nellix device (Ch-EVAS) may offer some potential advantages with respect to the seal between the endograft and the parallel grafts. This study aimed to investigate the feasibility and efficacy of the Nellix endovascular aneurysm sealing (EVAS) system in conjunction with parallel grafts for the treatment of juxtarenal and suprarenal aneurysms...
October 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27444361/surgical-treatment-of-abdominal-aortic-aneurysms-in-infancy-and-early-childhood
#15
Jonathan L Eliason, Dawn M Coleman, Enrique Criado, James C Stanley
OBJECTIVE: Pediatric abdominal aortic aneurysms (AAAs) are rare. The intent of this report was to review the presentation and surgical management of AAAs in infancy and early childhood. METHODS: The clinical courses of young children undergoing AAA surgery were subjected to a retrospective review and analysis. RESULTS: Eleven children, nine boys and two girls, ranging in age from 2 weeks to 6 years, underwent surgical treatment of AAA at the University of Michigan from 2002 to 2014...
July 18, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27438562/outcomes-of-surgery-for-patients-with-behcet-s-disease-causing-aortic-pseudoaneurysm-a-shift-from-open-surgery-to-endovascular-repair
#16
Chenyang Shen, Weihao Li, Yongbao Zhang, Qingle Li, Yang Jiao, Tao Zhang, Xiaoming Zhang
OBJECTIVES: Behcet's disease is a form of systematic vasculitis that affects vessels of various sizes. Aortic pseudoaneurysm is one of the most important causes of death among patients with Behcet's disease due to its high risk of rupture and associated mortality. Our study aimed to investigate the outcomes of Behcet's disease patients with aortic pseudoaneurysms undergoing open surgery and endovascular aortic repair. METHODS: From January 2003 to September 2014, ten consecutive patients undergoing surgery for aortic pseudoaneurysm met the diagnostic criteria for Behcet's disease...
July 2016: Clinics
https://www.readbyqxmd.com/read/27283745/vitamin-d-receptor-activation-reduces-angiotensin-ii-induced-dissecting-abdominal-aortic-aneurysm-in-apolipoprotein-e-knockout-mice
#17
Sara Martorell, Luisa Hueso, Herminia Gonzalez-Navarro, Aida Collado, Maria-Jesus Sanz, Laura Piqueras
OBJECTIVE: Abdominal aortic aneurysm (AAA) is a vascular disorder characterized by chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with AAA development; however, the potential direct effect of vitamin D3 on AAA remains unknown. This study evaluates the effect of oral treatment with the vitamin D3 receptor (VDR) ligand, calcitriol, on dissecting AAA induced by angiotensin-II (Ang-II) infusion in apoE(-/-) mice. APPROACH AND RESULTS: Oral treatment with calcitriol reduced Ang-II-induced dissecting AAA formation in apoE(-/-) mice, which was unrelated to systolic blood pressure or plasma cholesterol concentrations...
August 2016: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/27263819/an-uncommon-case-of-type-iii-endoleak-treated-with-a-custom-made-thoracic-stent-graft
#18
Mafalda Massara, David Barillà, Gaetana Franco, Alberto Volpe, Raffaele Serra, Giovanni De Caridi, Antonino Alberti, Pietro Volpe
Endovascular aortic repair (EVAR) has been shown to be a valid and minimally invasive alternative to open abdominal aortic aneurysm repair. A major shortcoming for EVAR is the need to submit patients to regular follow-up to detect potential complications such as endoleak, limb occlusion, aneurysm expansion, aneurysm rupture, infection, structural failure, and migration. In this case report, we describe an uncommon case of late type III endoleak due to complete detachment of the stent-graft main body segment from its suprarenal uncovered fixation stent...
August 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27210500/novel-methodology-for-characterizing-regional-variations-in-the-material-properties-of-murine-aortas
#19
Matthew R Bersi, Chiara Bellini, Paolo Di Achille, Jay D Humphrey, Katia Genovese, Stéphane Avril
Many vascular disorders, including aortic aneurysms and dissections, are characterized by localized changes in wall composition and structure. Notwithstanding the importance of histopathologic changes that occur at the microstructural level, macroscopic manifestations ultimately dictate the mechanical functionality and structural integrity of the aortic wall. Understanding structure-function relationships locally is thus critical for gaining increased insight into conditions that render a vessel susceptible to disease or failure...
July 1, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27183854/results-of-standard-suprarenal-fixation-endografts-for-abdominal-aortic-aneurysms-with-neck-length-%C3%A2-10%C3%A2-mm-in-high-risk-patients-unfit-for-open-repair-and-fenestrated-endograft
#20
Enrico Gallitto, Mauro Gargiulo, Antonio Freyrie, Claudio Bianchini Massoni, Rodolfo Pini, Chiara Mascoli, Gianluca Faggioli, Andrea Stella
OBJECTIVE: The aim of this study was to evaluate long-term outcomes of endovascular aneurysm repair (EVAR) using a standard suprarenal fixation endograft in abdominal aortic aneurysms (AAAs) with infrarenal neck length ≤10 mm (short-neck AAA [SN-AAA]). METHODS: From 2005 to 2010, data of high-risk patients with SN-AAA, unfit for open repair (OR) and fenestrated EVAR, were prospectively collected. Follow-up was performed by duplex ultrasound and contrast-enhanced ultrasound or computed tomography angiography at 1 month, 6 months, and 12 months and yearly thereafter...
September 2016: Journal of Vascular Surgery
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