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Burn edema

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https://www.readbyqxmd.com/read/28070608/xuebijing-injection-treatment-inhibits-vasopermeability-and-reduces-fluid-requirements-in-a-canine-burn-model
#1
F-B Tang, Y-L Dai, S Hu, L-Q Ma, J-Y Li, H-P Zhang, W-H Zhang, Y-G Li, H-B Wang, H-Y Lin, Q Hu, L Li
OBJECTIVE: High vasopermeability and excessive inflammation following severe burns may result in tissue edema, organ dysfunction and the loss of circulatory plasma volume, which can influence the doctor to do the prognosis to the patients. The study aims to examine whether Xuebijing injection (XBJ), an extracts of a traditional Chinese medicine used to treat sepsis in clinic, can reduces fluid requirements by inhibiting vasopermeability and tissue edema in a canine model after burn injury...
January 9, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28040362/role-of-the-nlrp3-inflammasome-in-a-model-of-acute-burn-induced-pain
#2
Jennifer R Deuis, Kathleen Yin, Matthew A Cooper, Kate Schroder, Irina Vetter
The NLRP3 inflammasome is a multi-protein complex that assembles in response to tissue damage or infection, triggering activation of caspase-1, an enzyme that converts interleukin (IL)-1β into its active form. A role for the NLRP3 inflammasome is emerging in inflammatory pain, but its influence in other pain types is largely unexamined. Therefore the aim of this study was to assess the role of the NLRP3 inflammasome and its downstream product caspase-1 in a model of acute burn-induced pain in male mice. A superficial burn was induced on the plantar surface of the left hind paw using a hot plate set at 52...
December 28, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27990665/clinical-assessment-of-a-new-755%C3%A2-nm-diode-laser-for-hair-removal-efficacy-safety-and-practicality-in-56-patients
#3
Josefina Royo, Javier Moreno-Moraga, Mario A Trelles
BACKGROUND AND OBJECTIVE: Recently, the first diode laser with a wavelength of 755 nm for in-motion hair removal came on the market. The objective of this study was to check its efficacy, safety, and practicality under different options for its use. METHODS: A prospective study in a heterogeneous group of 56 patients who had hair removed from various areas of their bodies using three different treatment methods. Four sessions were scheduled in all cases, with a gap of 3 months between each session...
December 19, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27926754/cone-photoreceptor-irregularity-on-adaptive-optics-scanning-laser-ophthalmoscopy-correlates-with-severity-of-diabetic-retinopathy-and-macular-edema
#4
Jan Lammer, Sonja G Prager, Michael C Cheney, Amel Ahmed, Salma H Radwan, Stephen A Burns, Paolo S Silva, Jennifer K Sun
Purpose: To determine whether cone density, spacing, or regularity in eyes with and without diabetes (DM) as assessed by high-resolution adaptive optics scanning laser ophthalmoscopy (AOSLO) correlates with presence of diabetes, diabetic retinopathy (DR) severity, or presence of diabetic macular edema (DME). Methods: Participants with type 1 or 2 DM and healthy controls underwent AOSLO imaging of four macular regions. Cone assessment was performed by independent graders for cone density, packing factor (PF), nearest neighbor distance (NND), and Voronoi tile area (VTA)...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27884557/laryngeal-trauma-following-an-inhalation-injury-a-review-and-case-report
#5
REVIEW
Gemma Hogg, Jay Goswamy, Sadie Khwaja, Nadeem Khwaja
The primary concern when managing a patient with inhalation injury is security of the airway. Airflow may be impeded by both edema of the upper airway and reduction of oxygen delivery to the lower respiratory tract. Although there has been much discussion regarding management of the latter, the focus of this article is the management of the former. This review aimed to determine the optimum management in burn victims with upper airway inhalation injury as an attempt to prevent laryngeal trauma leading to long-term voice disorders and upper airway dyspnea...
November 21, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27876335/globularia-alypum-methanolic-extract-improves-burn-wound-healing-process-and-inflammation-in-rats-and-possesses-antibacterial-and-antioxidant-activities
#6
Zohra Ghlissi, Rim Kallel, Assaad Sila, Bahira Harrabi, Rim Atheymen, Khaled Zeghal, Ali Bougatef, Zouheir Sahnoun
Burns are known as one of the most common and destructive forms of injury with a vast spectrum of consequences. Despite the discovery of various antibacterial and antiseptic agents, burn wound healing still has remained a challenge to modern medicine. Plants have been considered as potential agents for prevention and treatment of disorders in recent years. Globularia alypum L. (GA) is widely used in folk medicine against skin diseases and abscesses, however there is no scientific evidence justifying its use...
December 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27795221/-acute-generalized-exanthematous-pustulosis-induced-by-piroxicam
#7
Ingrid Bissinger, Gustavo Matute-Turizo, María Natalia Mejía-Barreneche
BACKGROUND: Between 62 and 90% of cases of acute generalized exanthematous pustulosis are caused by drugs. Its onset is rapid with generalized pustules, fever, and blood neutrophil count over 7000; pustules resolve spontaneously in less than 15 days. A case associated with piroxicam described. CASE REPORT: A 36-year-old with initial erythema of the thorax and abdomen, accompanied by burning, without fever, which later spread to his forearms, upper arms, and thighs, with face edema...
October 2016: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/27785082/tolerability-and-camouflaging-effect-of-corrective-makeup-for-acne-results-of-a-clinical-study-of-a-novel-face-compact-cream
#8
Giuseppe Monfrecola, Sara Cacciapuoti, Claudia Capasso, Mario Delfino, Gabriella Fabbrocini
BACKGROUND: A novel face compact cream (FCC) containing a new patented formulation was recently developed to provide acne patients with cosmetic camouflage for their lesions and to have beneficial effects on the multifactorial components of the disease. This pilot investigation aimed to evaluate the real-life tolerability, potential for comedogenicity and covering effect provided by this FCC. METHODS: This single-center study evaluated the FCC applied once daily for 28 days in 20 females with facial acne...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27784308/anti-inflammatory-and-antioxidative-effects-of-six-pentacyclic-triterpenes-isolated-from-the-mexican-copal-resin-of-bursera-copallifera
#9
Antonio Romero-Estrada, Amalia Maldonado-Magaña, Judith González-Christen, Silvia Marquina Bahena, María Luisa Garduño-Ramírez, Verónica Rodríguez-López, Laura Alvarez
BACKGROUND: Bursera copallifera (Burseraceae) releases a resin known as "copal ancho" which has been used, since pre-Colombian times, as ceremonially burned incense and to treat tooth ache, tumors, arthritis, cold, cough, and various inflammatory conditions; however, its anti-inflammatory potential is poorly studied. The aim of the present study was to isolate, quantify, and to investigate the anti-inflammatory activity of triterpene compounds isolated from the copal resin of B. copallifera...
October 26, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27775975/the-scourge-of-the-spurge-family-an-imitator-of-rhus-dermatitis
#10
Kimberly A Huerth, Jason E Hawkes, Laurence J Meyer, Douglas L Powell
The Euphorbiaceae family (commonly known as "spurge") is a large, diverse, and widely distributed family of plants that encompass around 300 genera and more than 8000 species. Their attractiveness and hearty nature have made them popular for both indoor ornamentation and outdoor landscaping. Despite their ubiquity, the potential to cause irritant contact dermatitis (ICD) is often overlooked in favor of more notorious causes of phytodermatitis, namely, Toxicodendron species and nettles. We examined case reports spanning 40 years and discovered that spurge-induced ICD tends to befall children and middle-aged adults who unwittingly encounter the plant through play or horticulture, respectively...
November 2016: Dermatitis
https://www.readbyqxmd.com/read/27759589/influences-of-macrohemodynamic-conditions-on-systemic-microhemodynamic-changes-in-burns
#11
Jochen-Frederick Hernekamp, Florian Neubrech, Tomke Cordts, Volker J Schmidt, Ulrich Kneser, Thomas Kremer
PURPOSE: The clinical course after major burns is characterized by microcirculatory changes and consecutive capillary leakage. However, current clinical monitoring does not properly assess microcirculation, whereas macrohemodynamic changes are continuously evaluated. Here, we assess if macrohemodynamic and microhemodynamic parameters after burn trauma are correlated in a rat model. METHODS: Burn plasma harvested from donor rats 4 hours after thermal injury (30% total body surface area, 100 °C water, 12 seconds) was administered intravenously to healthy animals during 2 hours of intravital microscopy (burn group [BG])...
October 17, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27741014/effect-of-1-and-6-hour-delayed-corneal-collagen-cross-linking-on-corneal-healing-in-a-rabbit-alkali-burn-model-clinical-and-histological-observations
#12
Omer Karti, Mehmet Ozgur Zengin, Esat Cinar, Merve Tutuncu, Eyyup Karahan, Asl Celik, Cem Kucukerdonmez
PURPOSE: To study the effect of 1- and 6-hour-delayed corneal collagen cross-linking (CXL) on wound-healing of experimental alkali burns of the cornea. METHODS: Twenty-four albino rabbits were used. Alkali burns were created using 1 M NaOH. The animals were divided randomly into 2 groups: group 1 (control group, n = 6) and group 2 (experimental group, n = 18). The experimental group was further divided into 3 subgroups as follows: group 2A, untreated (non-CXL) subgroup; group 2B, 1-hour-delayed CXL treatment subgroup; and group 2C, 6-hour-delayed CXL treatment subgroup...
October 12, 2016: Cornea
https://www.readbyqxmd.com/read/27669307/photodynamic-therapy-in-gynecologic-malignancies-a-review-of-the-roswell-park-cancer-institute-experience
#13
REVIEW
Paul C Mayor, Shashikant Lele
Photodynamic therapy (PDT) is a treatment modality used in the management of solid tumor malignancies that employs the use of a photosensitizing agent, a light source and oxygen in order to illicit a direct cytotoxic effect. Its use in gynecologic malignancies is somewhat novel and has been used for palliative and curative intent. At the Roswell Park Cancer Institute, the use of PDT in the management of gynecologic cancers began in the mid 1980s and since that time 35 patients have received PDT as a treatment for recurrent or metastatic cutaneous and vulvar, vaginal, anal, and cervical recurrences...
September 23, 2016: Cancers
https://www.readbyqxmd.com/read/27664086/respiratory-morbidity-after-childhood-burns-a-10-year-follow-up-study
#14
Janine M Duke, Sean M Randall, Mark W Fear, James H Boyd, Suzanne Rea, Fiona M Wood
BACKGROUND AND OBJECTIVE: The systemic responses triggered by burns and resuscitative measures may cause pulmonary damage and edema in the acute phase. These effects may occur in the absence of inhalation injury. Currently, there is a paucity of data on the recovery of the respiratory system postburn. This study aimed to examine 10-year hospital service use for respiratory morbidity in children with cutaneous burns and no smoke inhalation injury. METHODS: A population-based longitudinal study with 10-year follow-up using linked hospital and death from Western Australia for children <5 years when hospitalized for a first burn injury (n = 5290) between 1980 and 2012 and a frequency matched noninjury comparison cohort, randomly selected from Western Australia's birth registrations (n = 27 061)...
October 2016: Pediatrics
https://www.readbyqxmd.com/read/27648048/therapeutic-effects-of-topical-5-aminolevulinic-acid-photodynamic-therapy
#15
Yin-E Hu, Shu-Fang Dai, Bin Wang, Wei Qu, Jun-Ling Gao
OBJECTIVE: To evaluate the therapeutic effects of combined 5-aminolevulinic acid (ALA) and photodynamic therapy (PDT) on genital warts and the safety. METHODS: One hundred ten patients with genital warts who were treated in our hospital from June 2013 to October 2014 were selected. The warts and affected parts were disinfected with benzalkonium bromide solution, and the warts were covered with absorbent cotton that had already been added freshly prepared 20% ALA solution, packaged and fixed...
July 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27621783/intravitreal-phacoemulsification-using-torsional-handpiece-for-retained-lens-fragments
#16
Vinod Kumar, Brijesh Takkar
PURPOSE: To evaluate the results of intravitreal phacoemulsification with torsional hand piece in eyes with posteriorly dislocated lens fragments. METHODS: In this prospective, interventional case series, 15 eyes with retained lens fragments following phacoemulsification were included. All patients underwent standard three-port pars plana vitrectomy and intravitreal phacoemulsification using sleeveless, torsional hand piece (OZiL™, Alcon's Infiniti Vision System)...
July 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27600130/fluid-creep-and-over-resuscitation
#17
REVIEW
Jeffrey R Saffle
Fluid creep is the term applied to a burn resuscitation, which requires more fluid than predicted by standard formulas. Fluid creep is common today and is linked to several serious edema-related complications. Increased fluid requirements may accompany the appropriate resuscitation of massive injuries but dangerous fluid creep is also caused by overly permissive fluid infusion and the lack of colloid supplementation. Several strategies for recognizing and treating fluid creep are presented.
October 2016: Critical Care Clinics
https://www.readbyqxmd.com/read/27600124/monitoring-end-points-of-burn-resuscitation
#18
REVIEW
Daniel M Caruso, Marc R Matthews
This article discusses commonly used methods of monitoring and determining the end points of resuscitation. Each end point of resuscitation is examined as it relates to use in critically ill burn patients. Published medical literature, clinical trials, consensus trials, and expert opinion regarding end points of resuscitation were gathered and reviewed. Specific goals were a detailed examination of each method in the critical care population and how this methodology can be used in the burn patient. Although burn resuscitation is monitored and administered using the methodology as seen in medical/surgical intensive care settings, special consideration for excessive edema formation, metabolic derangements, and frequent operative interventions must be considered...
October 2016: Critical Care Clinics
https://www.readbyqxmd.com/read/27600123/colloids-in-acute-burn-resuscitation
#19
REVIEW
Robert Cartotto, David Greenhalgh
Colloids have been used in varying capacities throughout the history of formula-based burn resuscitation. There is sound experimental evidence that demonstrates colloids' ability to improve intravascular colloid osmotic pressure, expand intravascular volume, reduce resuscitation requirements, and limit edema in unburned tissue following a major burn. Fresh frozen plasma appears to be a useful and effective immediate burn resuscitation fluid but its benefits must be weighed against its costs, and risks of viral transmission and acute lung injury...
October 2016: Critical Care Clinics
https://www.readbyqxmd.com/read/27567703/involvement-of-mast-cells-and-histamine-in-edema-induced-in-mice-by-scolopendra-viridicornis-centipede-venom
#20
Bianca C L F Távora, Louise F Kimura, Marta M Antoniazzi, Thiago M Chiariello, Eliana L Faquim-Mauro, Katia C Barbaro
Bites caused by Scolopendra viridicornis centipede are mainly characterized by burning pain, paresthesia and edema. On this regard, the aim of this work was to study the involvement of mast cells and histamine in edema induced by Scolopendra viridicornis (Sv) centipede venom. The edema was analyzed on mice paws. The mice were pretreated with cromolyn (mast cell degranulation inhibitor) and antagonists of histamine receptors, such as promethazine (H1R), cimetidine (H2R) and thioperamide (H3/H4R). The analyses were carried out at different times after the injection of Sv venom (15 μg) or PBS in the footpad of mice...
October 2016: Toxicon: Official Journal of the International Society on Toxinology
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