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Möbius surgery

J Cen, X L Kang, J Yu, L Y Dong, Y Wei, K X Zhao
Objective: To investigate clinical features and the long-term surgery results of Möbius syndrome patients. Methods: This investigation presents a retrospective study of Möbius syndrome in 7 children we found since 2009. All 7 patients had MRI scan, ocular alignment in primary position, the limitation of versions and ductions and forced duction under general anesthesia. Early surgery is done to the 7 esotropia children. The pre-operative and post-operative outcomes, including the ocular alignment, deviation measurements and ocular rotations, were evaluated and compared...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
A Cardenas-Mejia, D Palafox
INTRODUCTION: Möbius syndrome is defined as a combined congenital bilateral facial and abducens nerve palsies. The main goal of treatment is to provide facial reanimation by means of a dynamic surgical procedure. The microneurovascular transfer of a free muscle transplant is the procedure of choice for facial animation in a child with facial paralysis. OBSERVATION: Between January 2008 and January 2017, 124 patients with the syndrome have been approached at our institution...
November 15, 2017: Annales de Chirurgie Plastique et Esthétique
Stefan Schleifenbaum, Michael Schmidt, Robert Möbius, Thomas Wolfskämpf, Christian Schröder, Ronny Grunert, Niels Hammer, Torsten Prietzel
BACKGROUND: To ensure adequate function after orthopedic tumor reconstruction, it is important to reattach the remaining soft tissue to the implant. This study aimed at obtaining mechanical properties of textile muscle-implant and muscle-bone connections in a preliminary test. METHODS: Two groups of soft-tissue attachment were mechanically tested and compared: Native bone-muscle samples obtained from human femora and muscles attached to a prosthetic implant by means of Trevira® attachment tubes...
April 6, 2016: BMC Musculoskeletal Disorders
Raimund H M Preidl, Patrick Möbius, Manuel Weber, Kerstin Amann, Friedrich W Neukam, Andreas Schlegel, Falk Wehrhan
AIM: Microvascular free tissue transfer is a standard method in head and neck reconstructive surgery. However, previous radiotherapy of the operative region is associated with an increased incidence in postoperative flap-related complications and complete flap loss. As transforming growth factor beta (TGF-β) 1 and galectin-3 are well known markers in the context of fibrosis and lectin-like oxidized low-density lipoprotein 1 (LOX-1) supports vascular atherosclerosis, the aim of this study was to evaluate the expression of TGF-β1 and related markers as well as LOX-1 in irradiated vessels...
June 2015: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Mariana Morales-Chávez, María A Ortiz-Rincones, Fabiola Suárez-Gorrin
Möbius syndrome is a congenital condition, the etiology when is not associated with misoprostol is not well defined. Signs and symptoms include difficulty swallowing, speech problems, drooling, strabismus, limitation of eye movement and more importantly, the facial blankness that these individuals have, result of the facial paralysis, due to atrophy of the cranial nerves that are involved in this condition. The ability to express emotions is affected and are considered "children without a smile." There is currently no treatment to solvent the birth defects, the treatment options for reduce these alterations is the surgical option that has as main objective to restore muscle function through various techniques, used as required, the possibilities of applying them, is taking into consideration the outcome of the procedure to execute...
October 1, 2013: Journal of Clinical and Experimental Dentistry
David Chwei-Chin Chuang, Johnny Chuieng-Yi Lu, Katerina Anesti
BACKGROUND: For the treatment of facial paralysis, functioning free muscle transplantation has become accepted standard treatment. Choice of donor nerve and number of surgery stages, however, are still matters of great debate. METHODS: Between 2000 and 2011, 36 patients (out of 329; 11 percent) with 42 functioning free muscle transplantations were treated using spinal accessory nerve (XI)-innervated muscle for facial reanimation as a one-stage procedure. Indications included bilateral or unilateral Möbius syndrome, severe postparetic facial synkinesis, and patient preference...
July 2013: Plastic and Reconstructive Surgery
Axel Linke, Felix Woitek, Marc W Merx, Conrad Schiefer, Sven Möbius-Winkler, David Holzhey, Ardawan Rastan, Jörg Ender, Thomas Walther, Malte Kelm, Friedrich W Mohr, Gerhard Schuler
BACKGROUND: Transcatheter aortic valve implantation (TAVI) using the Medtronic CoreValve (MCV) system might represent an alternative to conventional redo surgery in older high-risk patients with a failing aortic valve bioprosthesis. METHODS AND RESULTS: Symptomatic patients with failing aortic valve bioprosthesis, aged ≥65 years with a logistic EuroSCORE ≥10 % were considered for treatment. Local anesthesia was used to retrogradely implant the MCV system into the failing bioprosthetic valve...
October 2012: Circulation. Cardiovascular Interventions
B Bianchi, A Ferri, B Brevi, A Di Blasio, C Copelli, C Di Blasio, A Barbot, T Ferri, E Sesenna
Moebius syndrome is a rare disorder found in approximately 1/100,000 neonates and the treatment of facial palsy is now well established worldwide and consists of free-muscle transplants reinnervated with motor nerves. Dentofacial deformities are often detected in Moebius patients, and different degrees of micrognathia are often present, particularly in patients with complete expressions of Moebius syndrome. However only two published reports have described the surgical treatment of such anomalies in these patients; in both cases, the suggested approach consisted of orthognathic surgery followed by soft-tissue management...
January 2013: Journal of Cranio-maxillo-facial Surgery
Ming Cai, Guofang Shen, Bing Fang, Min Zhu, Li-xia Mao
PURPOSE: To investigate the treatment of severe skeletal open bite deformities in Möbius syndrome patients. MATERIALS AND METHODS: Three patients aged 17 to 24 years (2 male patients and 1 female patient) with Möbius syndrome were evaluated and treated with preoperative orthodontics, orthognathic surgery, and postoperative orthodontic management. One patient was treated by bilateral V osteotomies of the mandibular body and one patient with bilateral V osteotomies of the mandibular body plus a Le Fort I osteotomy...
June 2012: Journal of Oral and Maxillofacial Surgery
Heather Bemmels, Barbara Biesecker, Johanna L Schmidt, Alyson Krokosky, Rick Guidotti, Erica J Sutton
Objective : Reconstructive surgery to improve psychological well-being is commonly offered to children with craniofacial conditions. Few studies have explored the challenges of reconstructive surgery beyond the physical risks: poor treatment outcomes, infection, brain damage, and death. This qualitative study aims to understand the psychological and social implications such interventions can have for individuals with craniofacial conditions. Design : A total of 38 individuals between the ages of 12 and 61 with such craniofacial conditions as Sturge-Weber syndrome, Treacher Collins syndrome, Möbius syndrome, cleft lip and palate, Noonan syndrome, Crouzon syndrome, and amniotic band syndrome participated in semistructured video-recorded interviews...
March 2013: Cleft Palate-craniofacial Journal
Lisa L Sun, Glen A Gole
Möbius syndrome is a rare congenital disorder characterized by bilateral facial nerve palsy and abducens nerve palsy. It is associated with a wide spectrum of systemic and ocular manifestations; esotropia is commonly the reason for ophthalmic referral. There are few published studies in the literature on strabismus surgery in Möbius syndrome. An augmented vertical rectus muscle transposition in which lateral fixation sutures are used on the transposed vertical rectus muscles (Foster augmentation) has been used to correct esotropia caused by severe sixth nerve palsy and type 1 Duane syndrome...
December 2011: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Adriano Magli, Paola Bonavolontà, Raimondo Forte, Patrizia Vassallo
BACKGROUND: Patients with Möbius and Poland-Möbius syndromes may experience paralytic lagophthalmos. METHODS: This is a retrospective interventional case series. We report 1 case of Möbius syndrome and 2 cases of Poland-Möbius syndrome, wherein patients underwent lower blepharoplasty for lagophthalmos with 2 different surgical techniques. RESULTS: Two patients with Poland-Möbius syndrome presenting with bilateral lower eyelid entropion and paralytic lagophthalmos underwent lower eyelid elongation using right auricular cartilage via a transcutaneous approach...
November 2011: Journal of Craniofacial Surgery
S Dützmann, G Marquardt, V Seifert, K G Krishnan
BACKGROUND: The aim of the study was to retrospectively analyze the functional outcomes of microneurovascular facial reanimation using the masseteric innervation. PATIENTS AND METHODS: Seventeen patients with irreparable facial paralyses resulting from benign lesions involving the facial nuclei (n=14) or Möbius syndrome (n=3) were treated with free muscle flaps for oral commissural reanimation using ipsilateral masseteric innervation and using temporalis muscle transfer for eyelid reanimation...
October 2011: Der Nervenarzt
Raquel Guijarro-Martínez, Federico Hernández-Alfaro
BACKGROUND: Möbius sequence implies significant maxillofacial hard and soft tissue anomalies which nevertheless have not been addressed thoroughly in the scientific literature. OBJECTIVES: To report a case of complete Möbius sequence and discuss the management of maxillofacial hard and soft tissue anomalies. PATIENTS AND METHODS: A 15-year-old girl with complete Möbius underwent bimaxillary orthognathic surgery, horizontal sliding genioplasty and mentalis muscles reinsertion...
January 2012: Journal of Cranio-maxillo-facial Surgery
Anna Maria Buccoliero, Antonio Messineo, Francesca Castiglione, Duccio Rossi Degl'Innocenti, Raffaella Santi, Alessandra Martin, Gian Luigi Taddei
We present an exceptional association of splenogonadal fusion, Moebius syndrome, and intestinal intussusception. At the age of 1 year, the patient presented with vomiting, bloody stools, and abdominal distension. He underwent a laparotomy that revealed an ileo-ileal intussusception. Three days later, he underwent a new surgery for the reduction of a suspected inguinal hernia. A dark-red tubular structure consisting of splenic tissue was seen passing down through the processus vaginalis and attaching onto the left testicle...
2011: Fetal and Pediatric Pathology
Kartik G Krishnan, Gabriele Schackert, Volker Seifert
BACKGROUND: The functions of the human face are not only of esthetic significance but also extend into metaphoric nuances of psychology. The loss of function of one or both facial nerves has a remarkable impact on patients' lives. OBJECTIVE: To retrospectively analyze the functional outcomes of microneurovascular facial reanimation using masseteric innervation. METHODS: Seventeen patients with irreparable facial paralysis resulting from benign lesions involving the facial nuclei (n = 14) or Möbius syndrome (n = 3) were treated with free muscle flaps for oral commissural reanimation using ipsilateral masseteric innervation and using temporalis muscle transfer for eyelid reanimation...
September 2010: Neurosurgery
V Sturm, R Michels, M N Menke, K Landau
This article reviews the spectrum of possible motility disorders and ocular misalignment in patients with Möbius sequence. The various options for strabismus surgery are discussed and a stepwise algorithm is presented.
August 2010: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
A Momeni, S Eisenhardt, G B Stark, H Bannasch
One of the most demanding areas in plastic surgery is reconstruction of the smile in the setting of facial palsy. A multitude of surgical techniques and approaches have been proposed with variable success rates. The most frequently applied treatment algorithm is a two-stage approach with placement of a cross-facial nerve graft (CFNG) initially and subsequent free functional muscle transfer. As this approach has several limitations, the authors have performed single-stage reconstructions utilising the motor nerve to the masseter as the donor nerve...
April 2010: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
Erh-Kang Chou, David Chwei-Chin Cheung, Ellen Wen-Ching Ko, Yu-Ray Chen, Sophia Chia-Ning Chang
No abstract text is available yet for this article.
February 2010: Plastic and Reconstructive Surgery
Bernardo Bianchi, Chiara Copelli, Silvano Ferrari, Andrea Ferri, Enrico Sesenna
BACKGROUND: Moebius syndrome, a rare congenital disorder of varying severity, involves multiple cranial nerves and is characterized predominantly by bilateral or unilateral paralysis of the facial and abducens nerves. The paralysis of the VI and VII cranial nerves leads to a lack of function in the muscles they supply. Facial paralysis often causes bilabial incompetence with speech difficulties, oral incompetence, problems with eating and drinking, including pocketing of food in the cheek and dribbling, as well as severe drooling...
November 2009: Journal of Pediatric Surgery
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