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atlas of renal pathology

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https://www.readbyqxmd.com/read/29212269/low-neighbor-of-brca1-gene-expression-predicts-poor-clinical-outcome-and-resistance-of-sunitinib-in-clear-cell-renal-cell-carcinoma
#1
Wen Xiao, Zhiyong Xiong, Changfei Yuan, Lin Bao, Di Liu, Xiong Yang, Wencheng Li, Junwei Tong, Yan Qu, Lei Liu, Haibing Xiao, Hongmei Yang, Xiaoping Zhang, Ke Chen
Objective: To study the expression of Neighbor of Brca1 gene (NBR1) in clear cell renal cell carcinoma (ccRCC), renal cancer cells and the chemoresistance cells and to elucidate its clinical prognostic and chemoresistance value. Materials and Methods: We screened the NBR1 mRNA in ccRCC from The Cancer Genome Atlas (TCGA) database and examined expression levels of NBR1 mRNA in 48 cases of ccRCC tissues, renal cancer cell lines and chemoresistance cells by qRT-PCR...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29208006/identification-and-validation-of-a-44-gene-expression-signature-for-the-classification-of-renal-cell-carcinomas
#2
Qifeng Wang, Hualei Gan, Chengshu Chen, Yifeng Sun, Jinying Chen, Midie Xu, Weiwei Weng, Liyu Cao, Qinghua Xu, Jian Wang
BACKGROUND: Renal cancers account for more than 3% of all adult malignancies and cause more than 23,400 deaths per year in China alone. The four most common types of kidney tumours include clear cell, papillary, chromophobe and benign oncocytoma. These histological subtypes vary in their clinical course and prognosis, and different clinical strategies have been developed for their management. Some kidney tumours can be very difficult to distinguish based on the pathological assessment of morphology and immunohistochemistry...
December 6, 2017: Journal of Experimental & Clinical Cancer Research: CR
https://www.readbyqxmd.com/read/29169518/ajkd-atlas-of-renal-pathology-cystinosis
#3
Mark A Lusco, Behzad Najafian, Charles E Alpers, Agnes B Fogo
No abstract text is available yet for this article.
December 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29136101/identification-of-topological-features-in-renal-tumor-microenvironment-associated-with-patient-survival
#4
Jun Cheng, Xiaokui Mo, Xusheng Wang, Anil Parwani, Qianjin Feng, Kun Huang
Motivation: As a highly heterogeneous disease, the progression of tumor is not only achieved by unlimited growth of the tumor cells, but also supported, stimulated, and nurtured by the microenvironment around it. However traditional qualitative and/or semi-quantitative parameters obtained by pathologist's visual examination have very limited capability to capture this interaction between tumor and its microenvironment. With the advent of digital pathology, computerized image analysis may provide a better tumor characterization and give new insights into this problem...
November 9, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29113256/nudt-expression-is-predictive-of-prognosis-in-patients-with-clear-cell-renal-cell-carcinoma
#5
Yue Wang, Fangning Wan, Kun Chang, Xiaolin Lu, Bo Dai, Dingwei Ye
The nudix hydroxylase (NUDT) family of genes may have notable roles in cancer growth and metastasis. The present study aimed to determine the prognostic ability of NUDT genes in clear cell renal cell carcinoma (ccRCC). Data from 509 patients with ccRCC was obtained from The Cancer Genome Atlas (TCGA) database and 192 patient samples from Fudan University Shanghai Cancer Center (FUSCC) were analyzed in the present study. The expression profile of NUDT gene family members in the TCGA cohort was obtained from the TCGA RNA sequencing database...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29080693/s100a12-in-renal-and-cardiovascular-diseases
#6
REVIEW
Alireza Nazari, Hossein Khorramdelazad, Gholamhossein Hassanshahi, Andrew S Day, Atlas Mashayekhi Sardoo, Elnaz Tahmooresi Fard, Mehdi Abedinzadeh, Ali Esmaeili Nadimi
Expression of S100A12, a small calcium-binding protein, by neutrophils and monocytes/macrophages induces proinflammatory responses via ligation with the receptor for advanced glycation end-products (RAGE) and subsequent activation of intracellular signal transduction pathways such as the nuclear factor (NF)-κB pathway. Although S100A12 has been demonstrated to be a useful biomarker during inflammatory conditions, its precise role in the pathogenesis of renal and cardiovascular diseases has not been fully understood...
October 30, 2017: Life Sciences
https://www.readbyqxmd.com/read/29055354/ajkd-atlas-of-renal-pathology-fibronectin-glomerulopathy
#7
Mark A Lusco, Yi-Pu Chen, Hong Cheng, Hong-Rui Dong, Behzad Najafian, Charles E Alpers, Agnes B Fogo
No abstract text is available yet for this article.
November 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28941488/ajkd-atlas-of-renal-pathology-nail-patella-syndrome-associated-nephropathy
#8
Behzad Najafian, Kelly Smith, Mark A Lusco, Charles E Alpers, Agnes B Fogo
No abstract text is available yet for this article.
October 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28842062/ajkd-atlas-of-renal-pathology-ckd-of-unknown-cause-ckdu-%C3%A2-mesoamerican-nephropathy
#9
Mark A Lusco, Agnes B Fogo, Annika Östman Wernerson, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
September 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28834287/partial-nephrectomy-margin-imaging-using-structured-illumination-microscopy
#10
Mei Wang, David B Tulman, Andrew B Sholl, Sree H Mandava, Michael M Maddox, Benjamin R Lee, J Quincy Brown
Partial nephrectomy (PN) is the recommended procedure over radical nephrectomy (RN) for patients with renal masses < 4 cm in diameter (Stage T1a). Patients with > 4 cm renal masses can also be treated with PN, but have a higher risk for positive surgical margins. Positive surgical margins (PSM), when present, are indicative of poor clinical outcomes. The current gold-standard histopathology method is not well-suited for the identification of PSM intra-operatively due to processing time and destructive nature...
August 21, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28760334/erratum-regarding-ajkd-atlas-of-renal-pathology-kidney%C3%A2-disease-in-primary-sj%C3%A3-gren-syndrome-am%C3%A2-j%C3%A2-kidney%C3%A2-dis-%C3%A2-2017-69-6-e29-e30
#11
(no author information available yet)
No abstract text is available yet for this article.
October 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28753846/the-landscape-of-whole-genome-alterations-and-pathologic-features-in-genitourinary-malignancies-an-analysis-of-the-cancer-genome-atlas
#12
Mark W Ball, Michael A Gorin, Charles G Drake, Hans J Hammers, Mohamad E Allaf
BACKGROUND: The accumulation of somatic genetic alterations drives carcinogenesis. Little is known, however, about how the level of genetic alteration across an entire cancer genome affects tumor grade, stage or survival. OBJECTIVE: To investigate the influence of somatic mutation count (MC) and copy number variation (CNV) on pathologic and oncologic outcomes in patients with genitourinary malignancies in The Cancer Genome Atlas (TCGA). DESIGN, SETTING, AND PARTICIPANTS: TCGA data sets for adrenocortical carcinoma (ACC), bladder urothelial carcinoma (BLCA), chromophobe renal cell carcinoma (RCC; KICH), clear cell RCC (KIRC), papillary RCC (KIRP), pheochromocytoma and paraganglioma (PCPG), prostate adenocarcinoma (PRAD), and testis germ cell tumor (TGCT) were accessed via cBioportal...
February 8, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28739130/ajkd-atlas-of-renal-pathology-focal-and-diffuse-lupus-nephritis-isn-rps-class-iii-and-iv
#13
Agnes B Fogo, Mark A Lusco, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
August 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28739129/ajkd-atlas-of-renal-pathology-minimal-mesangial-and-mesangial-proliferative-lupus-nephritis-isn-rps-class-i-and-ii
#14
Agnes B Fogo, Mark A Lusco, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
August 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28739128/ajkd-atlas-of-renal-pathology-membranous-lupus-nephritis-isn-rps-class-v
#15
Mark A Lusco, Agnes B Fogo, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
August 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28731045/renal-cell-tumors-with-clear-cell-histology-and-intact-vhl-and-chromosome-3p-a-histological-review-of-tumors-from-the-cancer-genome-atlas-database
#16
Laura Favazza, Dhananjay A Chitale, Ravi Barod, Craig G Rogers, Shanker Kalyana-Sundaram, Nallasivam Palanisamy, Nilesh S Gupta, Sean R Williamson
Clear cell renal cell carcinoma is by far the most common form of kidney cancer; however, a number of histologically similar tumors are now recognized and considered distinct entities. The Cancer Genome Atlas published data set was queried (http://cbioportal.org) for clear cell renal cell carcinoma tumors lacking VHL gene mutation and chromosome 3p loss, for which whole-slide images were reviewed. Of the 418 tumors in the published Cancer Genome Atlas clear cell renal cell carcinoma database, 387 had VHL mutation, copy number loss for chromosome 3p, or both (93%)...
November 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28646986/ajkd-atlas-of-renal-pathology-lecithin-cholesterol-acyltransferase-lcat-deficiency
#17
Behzad Najafian, Mark A Lusco, Laura S Finn, Charles E Alpers, Agnes B Fogo
No abstract text is available yet for this article.
July 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28646985/ajkd-atlas-of-renal-pathology-anti-tubular-basement-membrane-antibody-disease
#18
Mark A Lusco, Agnes B Fogo, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
July 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28646984/ajkd-atlas-of-renal-pathology-chronic-interstitial-nephritis
#19
Agnes B Fogo, Mark A Lusco, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
July 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28532640/ajkd-atlas-of-renal-pathology-kidney-disease-in-primary-sj%C3%A3-gren-syndrome
#20
Agnes B Fogo, Mark A Lusco, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
June 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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